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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77165959
log Bayes Factor = 20.682
Chromosome 1   position 98,821,573  (GRCh37) Explore rs77165959 on Ensembl!
Variant rs77165959 is part of Cluster X0094

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.998 0.002 0.000
J44 Other chronic obstructive pulmonary disease
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.995 0.005 0.000
Chapter IX Diseases of the circulatory system
0.994 0.006 0.000
Chapter V Mental and behavioural disorders
0.994 0.006 0.000
J47 Bronchiectasis
0.992 0.008 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.990 0.010 0.000
C15-C26 Malignant neoplasms of digestive organs
0.990 0.010 0.000
J09-J18 Influenza and pneumonia
0.989 0.011 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.989 0.011 0.000
Chapter XI Diseases of the digestive system
0.986 0.014 0.000
K70-K77 Diseases of liver
0.983 0.017 0.000
J18 Pneumonia, organism unspecified
0.979 0.021 0.000
M70-M79 Other soft tissue disorders
0.976 0.024 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.975 0.025 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.972 0.028 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.970 0.030 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.969 0.031 0.000
K76 Other diseases of liver
0.967 0.033 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.967 0.033 0.000
J90-J94 Other diseases of pleura
0.964 0.036 0.000
D69 Purpura and other haemorrhagic conditions
0.962 0.038 0.000
S20-S29 Injuries to the thorax
0.960 0.040 0.000
J18.1 Lobar pneumonia, unspecified
0.959 0.041 0.000
Chapter VI Diseases of the nervous system
0.958 0.042 0.000
C18 Malignant neoplasm of colon
0.956 0.044 0.000
E70-E90 Metabolic disorders
0.954 0.046 0.000
M79.8 Other specified soft tissue disorders
0.954 0.046 0.000
I60-I69 Cerebrovascular diseases
0.953 0.047 0.000
S00-S09 Injuries to the head
0.949 0.051 0.000
C51-C58 Malignant neoplasms of female genital organs
0.946 0.054 0.000
J45 Asthma
0.943 0.057 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.942 0.058 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.941 0.059 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.939 0.061 0.000
G90-G99 Other disorders of the nervous system
0.938 0.062 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.937 0.063 0.000
S40-S49 Injuries to the shoulder and upper arm
0.936 0.064 0.000
K80 Cholelithiasis
0.934 0.066 0.000
E86 Volume depletion
0.930 0.070 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.930 0.070 0.000
M80-M85 Disorders of bone density and structure
0.924 0.076 0.000
S20 Superficial injury of thorax
0.924 0.076 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.922 0.078 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.920 0.080 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.918 0.082 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.916 0.084 0.000
D68 Other coagulation defects
0.915 0.085 0.000
J45.9 Asthma, unspecified
0.915 0.085 0.000
Chapter I Certain infectious and parasitic diseases
0.914 0.086 0.000
F10.0 Acute intoxication
0.913 0.087 0.000
C18.9 Colon, unspecified
0.911 0.089 0.000
J60-J70 Lung diseases due to external agents
0.907 0.093 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.904 0.096 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.894 0.106 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.891 0.109 0.000
J18.0 Bronchopneumonia, unspecified
0.891 0.109 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.888 0.112 0.000
J84 Other interstitial pulmonary diseases
0.888 0.112 0.000
K74 Fibrosis and cirrhosis of liver
0.883 0.117 0.000
I20-I25 Ischaemic heart diseases
0.882 0.118 0.000
Chapter VII Diseases of the eye and adnexa
0.882 0.118 0.000
J92 Pleural plaque
0.881 0.119 0.000
M20-M25 Other joint disorders
0.880 0.120 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.879 0.121 0.000
F30-F39 Mood [affective] disorders
0.875 0.125 0.000
S20.2 Contusion of thorax
0.875 0.125 0.000
K81 Cholecystitis
0.874 0.126 0.000
J81 Pulmonary oedema
0.874 0.126 0.000
I05-I09 Chronic rheumatic heart diseases
0.869 0.131 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.869 0.131 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.867 0.133 0.000
G96 Other disorders of central nervous system
0.864 0.136 0.000
S09 Other and unspecified injuries of head
0.862 0.138 0.000
K65-K67 Diseases of peritoneum
0.859 0.141 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.856 0.144 0.000
K76.6 Portal hypertension
0.856 0.144 0.000
C16 Malignant neoplasm of stomach
0.854 0.146 0.000
I10-I15 Hypertensive diseases
0.851 0.149 0.000
S42 Fracture of shoulder and upper arm
0.851 0.149 0.000
H25-H28 Disorders of lens
0.851 0.149 0.000
S32 Fracture of lumbar spine and pelvis
0.850 0.150 0.000
K81.9 Cholecystitis, unspecified
0.850 0.150 0.000
J90 Pleural effusion, not elsewhere classified
0.848 0.152 0.000
C77.2 Intra-abdominal lymph nodes
0.848 0.152 0.000
B95-B98 Bacterial, viral and other infectious agents
0.848 0.152 0.000
I25 Chronic ischaemic heart disease
0.847 0.153 0.000
F03 Unspecified dementia
0.847 0.153 0.000
D80-D89 Certain disorders involving the immune mechanism
0.845 0.155 0.000
E20-E35 Disorders of other endocrine glands
0.844 0.156 0.000
Chapter XXI Factors influencing health status and contact with health services
0.843 0.157 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.839 0.161 0.000
S06 Intracranial injury
0.837 0.163 0.000
I63 Cerebral infarction
0.836 0.164 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.836 0.164 0.000
H25 Senile cataract
0.836 0.164 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.835 0.165 0.000
C54 Malignant neoplasm of corpus uteri
0.834 0.166 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.834 0.166 0.000
J92.0 Pleural plaque with presence of asbestos
0.833 0.167 0.000
J69 Pneumonitis due to solids and liquids
0.831 0.169 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.831 0.169 0.000
Chapter XX External causes of morbidity and mortality
0.831 0.169 0.000
D60-D64 Aplastic and other anaemias
0.829 0.171 0.000
K80.4 Calculus of bile duct with cholecystitis
0.828 0.172 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.827 0.173 0.000
M84 Disorders of continuity of bone
0.822 0.178 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.819 0.181 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.819 0.181 0.000
K76.8 Other specified diseases of liver
0.819 0.181 0.000
C18.7 Sigmoid colon
0.818 0.182 0.000
I30-I52 Other forms of heart disease
0.818 0.182 0.000
I12 Hypertensive renal disease
0.815 0.185 0.000
K72 Hepatic failure, not elsewhere classified
0.812 0.188 0.000
J43 Emphysema
0.812 0.188 0.000
E40-E46 Malnutrition
0.811 0.189 0.000
B35-B49 Mycoses
0.811 0.189 0.000
M50-M54 Other dorsopathies
0.811 0.189 0.000
G96.0 Cerebrospinal fluid leak
0.810 0.190 0.000
M25 Other joint disorders, not elsewhere classified
0.808 0.192 0.000
S50-S59 Injuries to the elbow and forearm
0.807 0.193 0.000
E87.7 Fluid overload
0.807 0.193 0.000
K76.9 Liver disease, unspecified
0.806 0.194 0.000
C79 Secondary malignant neoplasm of other sites
0.804 0.196 0.000
T79-T79 Certain early complications of trauma
0.802 0.198 0.000
J14 Pneumonia due to Haemophilus influenzae
0.802 0.198 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.800 0.200 0.000
J94 Other pleural conditions
0.799 0.201 0.000
I08 Multiple valve diseases
0.799 0.201 0.000
Z60 Problems related to social environment
0.798 0.202 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.798 0.202 0.000
S70-S79 Injuries to the hip and thigh
0.797 0.203 0.000
C18.6 Descending colon
0.796 0.204 0.000
H25.0 Senile incipient cataract
0.794 0.206 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.793 0.207 0.000
M80 Osteoporosis with pathological fracture
0.792 0.208 0.000
T92 Sequelae of injuries of upper limb
0.792 0.208 0.000
G93 Other disorders of brain
0.791 0.209 0.000
D68.8 Other specified coagulation defects
0.790 0.210 0.000
T66-T78 Other and unspecified effects of external causes
0.790 0.210 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.789 0.210 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.789 0.211 0.000
J80 Adult respiratory distress syndrome
0.787 0.212 0.000
E23 Hypofunction and other disorders of pituitary gland
0.787 0.213 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.785 0.215 0.000
Z60.2 Living alone
0.784 0.216 0.000
C56 Malignant neoplasm of ovary
0.782 0.218 0.000
I12.0 Hypertensive renal disease with renal failure
0.782 0.218 0.000
S02 Fracture of skull and facial bones
0.780 0.220 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.780 0.220 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.780 0.220 0.000
S09.9 Unspecified injury of head
0.779 0.221 0.000
D66 Hereditary factor VIII deficiency
0.779 0.221 0.000
F31 Bipolar affective disorder
0.778 0.222 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.778 0.222 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.778 0.222 0.000
E87.3 Alkalosis
0.778 0.222 0.000
J69.0 Pneumonitis due to food and vomit
0.777 0.223 0.000
M71 Other bursopathies
0.776 0.224 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.776 0.224 0.000
E65-E68 Obesity and other hyperalimentation
0.775 0.225 0.000
K82 Other diseases of gallbladder
0.775 0.225 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.775 0.225 0.000
S32.5 Fracture of pubis
0.774 0.226 0.000
K80.8 Other cholelithiasis
0.774 0.226 0.000
I61 Intracerebral haemorrhage
0.772 0.228 0.000
H25.8 Other senile cataract
0.771 0.229 0.000
M79.5 Residual foreign body in soft tissue
0.771 0.229 0.000
K65 Peritonitis
0.770 0.230 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.769 0.231 0.000
K75 Other inflammatory liver diseases
0.769 0.231 0.000
I69 Sequelae of cerebrovascular disease
0.768 0.232 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.767 0.233 0.000
J00-J06 Acute upper respiratory infections
0.766 0.233 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.766 0.234 0.000
D73 Diseases of spleen
0.766 0.234 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.765 0.235 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.765 0.235 0.000
W00-W19 Falls
0.765 0.235 0.000
M79.6 Pain in limb
0.764 0.236 0.000
M24 Other specific joint derangements
0.763 0.237 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.762 0.238 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.762 0.238 0.000
S90-S99 Injuries to the ankle and foot
0.759 0.241 0.000
M79.1 Myalgia
0.759 0.241 0.000
S10-S19 Injuries to the neck
0.759 0.241 0.000
I22 Subsequent myocardial infarction
0.759 0.241 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.756 0.243 0.000
C51 Malignant neoplasm of vulva
0.756 0.244 0.000
H40-H42 Glaucoma
0.755 0.245 0.000
C54.1 Endometrium
0.754 0.246 0.000
I51 Complications and ill-defined descriptions of heart disease
0.754 0.246 0.000
K70 Alcoholic liver disease
0.754 0.246 0.000
M91-M94 Chondropathies
0.754 0.246 0.000
M15-M19 Arthrosis
0.754 0.246 0.000
S42.0 Fracture of clavicle
0.753 0.247 0.000
T90 Sequelae of injuries of head
0.753 0.247 0.000
K83 Other diseases of biliary tract
0.752 0.248 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.752 0.248 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.750 0.250 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.750 0.250 0.000
K85 Acute pancreatitis
0.749 0.251 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.748 0.252 0.000
C20 Malignant neoplasm of rectum
0.748 0.252 0.000
M51 Other intervertebral disk disorders
0.747 0.252 0.000
M79.2 Neuralgia and neuritis, unspecified
0.744 0.256 0.000
I08.0 Disorders of both mitral and aortic valves
0.744 0.256 0.000
C92 Myeloid leukaemia
0.742 0.258 0.000
I42 Cardiomyopathy
0.741 0.259 0.000
I62 Other nontraumatic intracranial haemorrhage
0.740 0.260 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.740 0.260 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.739 0.261 0.000
K74.6 Other and unspecified cirrhosis of liver
0.739 0.261 0.000
B37 Candidiasis
0.738 0.262 0.000
M60-M63 Disorders of muscles
0.737 0.263 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.737 0.263 0.000
G20-G26 Extrapyramidal and movement disorders
0.736 0.264 0.000
I25.4 Coronary artery aneurysm
0.734 0.266 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.733 0.267 0.000
Chapter XIV Diseases of the genitourinary system
0.733 0.267 0.000
D68.9 Coagulation defect, unspecified
0.732 0.268 0.000
G91 Hydrocephalus
0.732 0.268 0.000
D69.6 Thrombocytopenia, unspecified
0.731 0.269 0.000
C16.9 Stomach, unspecified
0.730 0.270 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.730 0.270 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.728 0.271 0.000
C43 Malignant melanoma of skin
0.728 0.272 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.728 0.272 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.728 0.272 0.000
G90 Disorders of autonomic nervous system
0.727 0.273 0.000
M85 Other disorders of bone density and structure
0.726 0.273 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.726 0.273 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.725 0.275 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.724 0.276 0.000
M76 Enthesopathies of lower limb, excluding foot
0.723 0.277 0.000
S40 Superficial injury of shoulder and upper arm
0.721 0.279 0.000
J95-J99 Other diseases of the respiratory system
0.720 0.280 0.000
S32.50 Fracture of pubis (closed)
0.719 0.281 0.000
E50-E64 Other nutritional deficiencies
0.718 0.281 0.000
F99-F99 Unspecified mental disorder
0.718 0.282 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.718 0.282 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.717 0.283 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.716 0.284 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.716 0.284 0.000
D55-D59 Haemolytic anaemias
0.715 0.284 0.000
I51.7 Cardiomegaly
0.716 0.284 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.715 0.285 0.000
J46 Status asthmaticus
0.715 0.285 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.715 0.285 0.000
E23.0 Hypopituitarism
0.714 0.286 0.000
J11 Influenza, virus not identified
0.714 0.286 0.000
M00-M03 Infectious arthropathies
0.713 0.287 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.713 0.287 0.000
I00-I02 Acute rheumatic fever
0.713 0.287 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.287 0.000
F70-F79 Mental retardation
0.712 0.287 0.000
I26 Pulmonary embolism
0.712 0.288 0.000
G95 Other diseases of spinal cord
0.712 0.288 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.710 0.289 0.000
C45 Mesothelioma
0.710 0.290 0.000
C53 Malignant neoplasm of cervix uteri
0.710 0.290 0.000
D67 Hereditary factor IX deficiency
0.710 0.290 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.710 0.290 0.000
C21 Malignant neoplasm of anus and anal canal
0.710 0.290 0.000
C17 Malignant neoplasm of small intestine
0.710 0.290 0.000
C23 Malignant neoplasm of gallbladder
0.710 0.290 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.710 0.290 0.000
J17 Pneumonia in diseases classified elsewhere
0.709 0.291 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.709 0.291 0.000
J12 Viral pneumonia, not elsewhere classified
0.709 0.291 0.000
J09 Influenza due to certain identified influenza virus
0.709 0.291 0.000
D50-D53 Nutritional anaemias
0.709 0.291 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.708 0.292 0.000
F60-F69 Disorders of adult personality and behaviour
0.707 0.292 0.000
J10 Influenza due to identified influenza virus
0.707 0.293 0.000
M34 Systemic sclerosis
0.707 0.293 0.000
H55-H59 Other disorders of eye and adnexa
0.707 0.293 0.000
C18.0 Caecum
0.706 0.294 0.000
H25.9 Senile cataract, unspecified
0.705 0.295 0.000
K77 Liver disorders in diseases classified elsewhere
0.705 0.295 0.000
K73 Chronic hepatitis, not elsewhere classified
0.705 0.295 0.000
K71 Toxic liver disease
0.705 0.295 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.704 0.296 0.000
F32 Depressive episode
0.704 0.296 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.704 0.296 0.000
J18.8 Other pneumonia, organism unspecified
0.702 0.298 0.000
J18.2 Hypostatic pneumonia, unspecified
0.702 0.298 0.000
Chapter XXII Codes for special purposes
0.702 0.298 0.000
C77.9 Lymph node, unspecified
0.702 0.298 0.000
D73.0 Hyposplenism
0.700 0.300 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.700 0.300 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.699 0.301 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.699 0.301 0.000
I60 Subarachnoid haemorrhage
0.698 0.302 0.000
S29 Other and unspecified injuries of thorax
0.698 0.302 0.000
E46 Unspecified protein-energy malnutrition
0.698 0.302 0.000
J04 Acute laryngitis and tracheitis
0.697 0.303 0.000
C77.4 Inguinal and lower limb lymph nodes
0.697 0.303 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.697 0.303 0.000
I50 Heart failure
0.697 0.303 0.000
B25-B34 Other viral diseases
0.697 0.303 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.696 0.303 0.000
D68.0 Von Willebrand's disease
0.696 0.303 0.000
S42.4 Fracture of lower end of humerus
0.696 0.304 0.000
I63.9 Cerebral infarction, unspecified
0.696 0.304 0.000
K74.5 Biliary cirrhosis, unspecified
0.695 0.305 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.694 0.305 0.000
K76.7 Hepatorenal syndrome
0.694 0.306 0.000
K76.5 Hepatic veno-occlusive disease
0.694 0.306 0.000
K76.4 Peliosis hepatis
0.694 0.306 0.000
K76.3 Infarction of liver
0.694 0.306 0.000
K76.2 Central haemorrhagic necrosis of liver
0.694 0.306 0.000
K76.1 Chronic passive congestion of liver
0.694 0.306 0.000
M79.9 Soft tissue disorder, unspecified
0.693 0.306 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.693 0.306 0.000
M79.3 Panniculitis, unspecified
0.693 0.306 0.000
S80-S89 Injuries to the knee and lower leg
0.694 0.306 0.000
G81 Hemiplegia
0.693 0.306 0.000
K74.3 Primary biliary cirrhosis
0.693 0.307 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.693 0.307 0.000
G93.3 Postviral fatigue syndrome
0.693 0.307 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.691 0.309 0.000
D69.9 Haemorrhagic condition, unspecified
0.690 0.310 0.000
D69.8 Other specified haemorrhagic conditions
0.690 0.310 0.000
D69.5 Secondary thrombocytopenia
0.690 0.310 0.000
D69.4 Other primary thrombocytopenia
0.690 0.310 0.000
D69.2 Other nonthrombocytopenic purpura
0.690 0.310 0.000
D69.1 Qualitative platelet defects
0.690 0.310 0.000
D69.0 Allergic purpura
0.690 0.310 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.690 0.310 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.689 0.311 0.000
I46 Cardiac arrest
0.689 0.311 0.000
D80 Immunodeficiency with predominantly antibody defects
0.689 0.311 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.689 0.311 0.000
S26 Injury of heart
0.689 0.311 0.000
S25 Injury of blood vessels of thorax
0.689 0.311 0.000
S24 Injury of nerves and spinal cord at thorax level
0.689 0.311 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.689 0.311 0.000
S21 Open wound of thorax
0.689 0.311 0.000
M86-M90 Other osteopathies
0.688 0.312 0.000
G83 Other paralytic syndromes
0.687 0.313 0.000
C18.8 Overlapping lesion of colon
0.686 0.314 0.000
C18.5 Splenic flexure
0.686 0.314 0.000
C18.1 Appendix
0.686 0.314 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.685 0.315 0.000
E85 Amyloidosis
0.684 0.316 0.000
E84 Cystic fibrosis
0.684 0.316 0.000
E79 Disorders of purine and pyrimidine metabolism
0.684 0.316 0.000
E77 Disorders of glycoprotein metabolism
0.684 0.316 0.000
E76 Disorders of glycosaminoglycan metabolism
0.684 0.316 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.684 0.316 0.000
E74 Other disorders of carbohydrate metabolism
0.684 0.316 0.000
E73 Lactose intolerance
0.684 0.316 0.000
E72 Other disorders of amino-acid metabolism
0.684 0.316 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.684 0.316 0.000
E70 Disorders of aromatic amino-acid metabolism
0.684 0.316 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.684 0.316 0.000
I35 Nonrheumatic aortic valve disorders
0.684 0.316 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.684 0.316 0.000
M79.88 Other specified soft tissue disorders (Other)
0.684 0.316 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.684 0.316 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.684 0.316 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.684 0.316 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.684 0.316 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.684 0.316 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.684 0.316 0.000
C77.1 Intrathoracic lymph nodes
0.684 0.316 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.683 0.317 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.683 0.317 0.000
S42.00 Fracture of clavicle (closed)
0.683 0.317 0.000
S60-S69 Injuries to the wrist and hand
0.683 0.317 0.000
C18.3 Hepatic flexure
0.682 0.317 0.000
M21 Other acquired deformities of limbs
0.682 0.318 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.682 0.318 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.681 0.318 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.681 0.319 0.000
J93 Pneumothorax
0.681 0.319 0.000
S27 Injury of other and unspecified intrathoracic organs
0.681 0.319 0.000
S08 Traumatic amputation of part of head
0.680 0.320 0.000
S07 Crushing injury of head
0.680 0.320 0.000
S05 Injury of eye and orbit
0.680 0.320 0.000
S04 Injury of cranial nerves
0.680 0.320 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.680 0.320 0.000
G70-G73 Diseases of myoneural junction and muscle
0.680 0.320 0.000
I25.2 Old myocardial infarction
0.680 0.320 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.680 0.320 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.679 0.321 0.000
M72 Fibroblastic disorders
0.679 0.321 0.000
E27 Other disorders of adrenal gland
0.679 0.321 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.678 0.322 0.000
C58 Malignant neoplasm of placenta
0.678 0.322 0.000
C52 Malignant neoplasm of vagina
0.678 0.322 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.678 0.322 0.000
I77 Other disorders of arteries and arterioles
0.677 0.323 0.000
S09.8 Other specified injuries of head
0.677 0.323 0.000
J43.9 Emphysema, unspecified
0.677 0.323 0.000
D68.2 Hereditary deficiency of other clotting factors
0.677 0.323 0.000
J45.8 Mixed asthma
0.676 0.324 0.000
J45.1 Nonallergic asthma
0.676 0.324 0.000
F80-F89 Disorders of psychological development
0.676 0.324 0.000
W20-W49 Exposure to inanimate mechanical forces
0.676 0.324 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.676 0.324 0.000
M35 Other systemic involvement of connective tissue
0.673 0.327 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.673 0.327 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.673 0.327 0.000
G92 Toxic encephalopathy
0.673 0.327 0.000
M25.5 Pain in joint
0.672 0.328 0.000
J18.9 Pneumonia, unspecified
0.672 0.328 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.672 0.328 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.672 0.328 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.672 0.328 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.672 0.328 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.672 0.328 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.672 0.328 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.672 0.328 0.000
F11 Mental and behavioural disorders due to use of opioids
0.672 0.328 0.000
K72.9 Hepatic failure, unspecified
0.671 0.329 0.000
S48 Traumatic amputation of shoulder and upper arm
0.671 0.329 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.671 0.329 0.000
S44 Injury of nerves at shoulder and upper arm level
0.671 0.329 0.000
S41 Open wound of shoulder and upper arm
0.671 0.329 0.000
S47 Crushing injury of shoulder and upper arm
0.671 0.329 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.670 0.330 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.670 0.330 0.000
K80.3 Calculus of bile duct with cholangitis
0.669 0.331 0.000
N20-N23 Urolithiasis
0.669 0.331 0.000
M19 Other arthrosis
0.669 0.331 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.667 0.333 0.000
E87.4 Mixed disorder of acid-base balance
0.667 0.333 0.000
K65.8 Other peritonitis
0.667 0.333 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.666 0.334 0.000
S06.8 Other intracranial injuries
0.666 0.334 0.000
F31.9 Bipolar affective disorder, unspecified
0.665 0.335 0.000
C16.0 Cardia
0.665 0.335 0.000
F01 Vascular dementia
0.665 0.335 0.000
H40 Glaucoma
0.664 0.336 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.664 0.336 0.000
M40-M43 Deforming dorsopathies
0.664 0.336 0.000
M25.4 Effusion of joint
0.664 0.336 0.000
K90-K93 Other diseases of the digestive system
0.664 0.336 0.000
I25.3 Aneurysm of heart
0.663 0.337 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.663 0.337 0.000
I72 Other aneurysm
0.663 0.337 0.000
M83 Adult osteomalacia
0.663 0.337 0.000
M82 Osteoporosis in diseases classified elsewhere
0.663 0.337 0.000
S42.1 Fracture of scapula
0.663 0.337 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.663 0.337 0.000
S20.7 Multiple superficial injuries of thorax
0.662 0.337 0.000
S20.4 Other superficial injuries of back wall of thorax
0.662 0.337 0.000
S20.3 Other superficial injuries of front wall of thorax
0.662 0.337 0.000
S20.1 Other and unspecified superficial injuries of breast
0.662 0.337 0.000
S20.0 Contusion of breast
0.662 0.337 0.000
M51.2 Other specified intervertebral disk displacement
0.662 0.338 0.000
K74.0 Hepatic fibrosis
0.661 0.338 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.661 0.339 0.000
S37 Injury of urinary and pelvic organs
0.661 0.339 0.000
S36 Injury of intra-abdominal organs
0.661 0.339 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.661 0.339 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.661 0.339 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.661 0.339 0.000
S31 Open wound of abdomen, lower back and pelvis
0.661 0.339 0.000
E23.6 Other disorders of pituitary gland
0.660 0.339 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.660 0.340 0.000
J94.1 Fibrothorax
0.660 0.340 0.000
G30-G32 Other degenerative diseases of the nervous system
0.660 0.340 0.000
F10.9 Unspecified mental and behavioural disorder
0.660 0.340 0.000
F10.8 Other mental and behavioural disorders
0.660 0.340 0.000
F10.7 Residual and late-onset psychotic disorder
0.660 0.340 0.000
F10.6 Amnesic syndrome
0.660 0.340 0.000
F10.5 Psychotic disorder
0.660 0.340 0.000
F10.4 Withdrawal state with delirium
0.660 0.340 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.659 0.341 0.000
B37.9 Candidiasis, unspecified
0.659 0.341 0.000
H10-H13 Disorders of conjunctiva
0.658 0.342 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.658 0.342 0.000
Z30 Contraceptive management
0.657 0.343 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.656 0.343 0.000
F02 Dementia in other diseases classified elsewhere
0.656 0.343 0.000
F09 Unspecified organic or symptomatic mental disorder
0.656 0.343 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.656 0.343 0.000
D68.6 Other Thrombophilia
0.656 0.344 0.000
D68.5 Primary Thrombophilia
0.656 0.344 0.000
D68.4 Acquired coagulation factor deficiency
0.656 0.344 0.000
D68.1 Hereditary factor XI deficiency
0.656 0.344 0.000
F10.2 Dependence syndrome
0.656 0.344 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.656 0.344 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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