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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77196615
log Bayes Factor = 18.4565
Chromosome 19   position 45,380,335  (GRCh37) Explore rs77196615 on Ensembl!
Variant rs77196615 is part of Cluster X0148

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.000 0.000 0.000
Z51 Other medical care
1.000 0.000 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.997 0.003 0.000
Z96 Presence of other functional implants
0.997 0.003 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.997 0.003 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.997 0.003 0.000
Z51.1 Chemotherapy session for neoplasm
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
Chapter I Certain infectious and parasitic diseases
0.996 0.004 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.996 0.004 0.000
Z88.6 Personal history of allergy to analgesic agent
0.994 0.006 0.000
C34 Malignant neoplasm of bronchus and lung
0.993 0.007 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.992 0.008 0.000
A30-A49 Other bacterial diseases
0.992 0.008 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.990 0.010 0.000
C34.1 Upper lobe, bronchus or lung
0.988 0.012 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.987 0.013 0.000
A41 Other septicaemia
0.986 0.014 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.986 0.014 0.000
Z96.6 Presence of orthopaedic joint implants
0.986 0.014 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.984 0.016 0.000
A41.9 Septicaemia, unspecified
0.979 0.021 0.000
C50-C50 Malignant neoplasm of breast
0.973 0.027 0.000
Z85 Personal history of malignant neoplasm
0.973 0.027 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.967 0.033 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.967 0.033 0.000
Y84.8 Other medical procedures
0.964 0.036 0.000
Y43 Primarily systemic agents
0.963 0.037 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.960 0.040 0.000
Z51.3 Blood transfusion without reported diagnosis
0.955 0.045 0.000
C50 Malignant neoplasm of breast
0.955 0.045 0.000
Y43.3 Other antineoplastic drugs
0.942 0.058 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.936 0.064 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.936 0.064 0.000
Chapter XIV Diseases of the genitourinary system
0.934 0.066 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.923 0.077 0.000
C50.9 Breast, unspecified
0.918 0.082 0.000
N17-N19 Renal failure
0.916 0.084 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.915 0.085 0.000
Z46 Fitting and adjustment of other devices
0.912 0.088 0.000
W00-W19 Falls
0.911 0.089 0.000
D10-D36 Benign neoplasms
0.911 0.089 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.909 0.091 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.909 0.091 0.000
Chapter X Diseases of the respiratory system
0.908 0.092 0.000
Z40 Prophylactic surgery
0.907 0.093 0.000
Z92 Personal history of medical treatment
0.903 0.097 0.000
E10-E14 Diabetes mellitus
0.903 0.097 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.900 0.100 0.000
Chapter VIII Diseases of the ear and mastoid process
0.897 0.103 0.000
D25 Leiomyoma of uterus
0.894 0.106 0.000
C50.4 Upper-outer quadrant of breast
0.888 0.112 0.000
Z92.3 Personal history of irradiation
0.885 0.115 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.884 0.116 0.000
E70-E90 Metabolic disorders
0.881 0.119 0.000
Y52 Agents primarily affecting the cardiovascular system
0.879 0.121 0.000
D25.9 Leiomyoma of uterus, unspecified
0.871 0.129 0.000
C34.9 Bronchus or lung, unspecified
0.869 0.130 0.000
N17 Acute renal failure
0.869 0.131 0.000
Z47 Other orthopaedic follow-up care
0.865 0.135 0.000
J30-J39 Other diseases of upper respiratory tract
0.863 0.137 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.860 0.140 0.000
Z96.0 Presence of urogenital implants
0.860 0.140 0.000
Y40 Systemic antibiotics
0.860 0.140 0.000
E10 Insulin-dependent diabetes mellitus
0.858 0.142 0.000
Z45 Adjustment and management of implanted device
0.857 0.143 0.000
Z89 Acquired absence of limb
0.856 0.144 0.000
D70 Agranulocytosis
0.851 0.149 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.850 0.150 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.847 0.153 0.000
N19 Unspecified renal failure
0.846 0.154 0.000
Z51.5 Palliative care
0.845 0.155 0.000
D72 Other disorders of white blood cells
0.845 0.155 0.000
Z96.8 Presence of other specified functional implants
0.843 0.157 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.842 0.158 0.000
C91 Lymphoid leukaemia
0.842 0.158 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.841 0.159 0.000
Z88.5 Personal history of allergy to narcotic agent
0.839 0.161 0.000
Z93 Artificial opening status
0.839 0.161 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.837 0.163 0.000
Z46.6 Fitting and adjustment of urinary device
0.836 0.164 0.000
E88 Other metabolic disorders
0.836 0.164 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.836 0.164 0.000
N17.9 Acute renal failure, unspecified
0.835 0.165 0.000
A49 Bacterial infection of unspecified site
0.832 0.168 0.000
N92 Excessive, frequent and irregular menstruation
0.832 0.168 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.831 0.169 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.830 0.170 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.828 0.172 0.000
D00-D09 In situ neoplasms
0.828 0.172 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.826 0.174 0.000
Y84.0 Cardiac catheterisation
0.824 0.176 0.000
E10.9 Without complications
0.820 0.180 0.000
Z50 Care involving use of rehabilitation procedures
0.818 0.182 0.000
B95-B98 Bacterial, viral and other infectious agents
0.818 0.182 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.817 0.183 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.816 0.184 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.815 0.185 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.814 0.186 0.000
Z96.1 Presence of intraocular lens
0.814 0.186 0.000
T66-T78 Other and unspecified effects of external causes
0.813 0.187 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.811 0.189 0.000
D80-D89 Certain disorders involving the immune mechanism
0.811 0.189 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.807 0.193 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.805 0.195 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.804 0.196 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.803 0.197 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.802 0.198 0.000
D25.2 Subserosal leiomyoma of uterus
0.800 0.200 0.000
J20-J22 Other acute lower respiratory infections
0.797 0.203 0.000
Y83.5 Amputation of limb(s)
0.794 0.206 0.000
S00-S09 Injuries to the head
0.794 0.206 0.000
B35-B49 Mycoses
0.792 0.208 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.791 0.209 0.000
E87.5 Hyperkalaemia
0.791 0.209 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.790 0.210 0.000
J32 Chronic sinusitis
0.789 0.211 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.788 0.212 0.000
H65-H75 Diseases of middle ear and mastoid
0.784 0.215 0.000
D75 Other diseases of blood and blood-forming organs
0.784 0.216 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.784 0.216 0.000
C50.2 Upper-inner quadrant of breast
0.780 0.220 0.000
D72.8 Other specified disorders of white blood cells
0.780 0.220 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.779 0.221 0.000
W19 Unspecified fall
0.778 0.222 0.000
Y83.9 Surgical procedure, unspecified
0.772 0.228 0.000
Z98 Other postsurgical states
0.767 0.233 0.000
Z41 Procedures for purposes other than remedying health state
0.766 0.234 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.766 0.234 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.764 0.236 0.000
Y84.2 Radiological procedure and radiotherapy
0.762 0.238 0.000
W20-W49 Exposure to inanimate mechanical forces
0.760 0.240 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.760 0.240 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.760 0.240 0.000
J33 Nasal polyp
0.759 0.241 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.759 0.241 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.757 0.243 0.000
Z52 Donors of organs and tissues
0.756 0.244 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.756 0.244 0.000
T93 Sequelae of injuries of lower limb
0.756 0.244 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.756 0.244 0.000
Chapter XXII Codes for special purposes
0.755 0.245 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.752 0.248 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.752 0.248 0.000
Z45.2 Adjustment and management of vascular access device
0.751 0.249 0.000
J32.9 Chronic sinusitis, unspecified
0.750 0.250 0.000
V20-V29 Motorcycle rider injured in transport accident
0.749 0.251 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.748 0.252 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.748 0.252 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.748 0.252 0.000
C15-C26 Malignant neoplasms of digestive organs
0.747 0.253 0.000
S40-S49 Injuries to the shoulder and upper arm
0.747 0.253 0.000
C34.0 Main bronchus
0.744 0.256 0.000
T86 Failure and rejection of transplanted organs and tissues
0.742 0.257 0.000
N10-N16 Renal tubulo-interstitial diseases
0.742 0.258 0.000
Z47.8 Other specified orthopaedic follow-up care
0.742 0.258 0.000
D22 Melanocytic naevi
0.741 0.259 0.000
Z49 Care involving dialysis
0.740 0.260 0.000
V80-V89 Other land transport accidents
0.740 0.260 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.739 0.261 0.000
D34 Benign neoplasm of thyroid gland
0.739 0.261 0.000
C91.1 Chronic lymphocytic leukaemia
0.738 0.262 0.000
W07 Fall involving chair
0.737 0.263 0.000
N30-N39 Other diseases of urinary system
0.737 0.263 0.000
T79-T79 Certain early complications of trauma
0.735 0.265 0.000
H90-H95 Other disorders of ear
0.732 0.267 0.000
E87.0 Hyperosmolality and hypernatraemia
0.731 0.268 0.000
E20-E35 Disorders of other endocrine glands
0.731 0.269 0.000
W13 Fall from, out of or through building or structure
0.730 0.270 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.730 0.270 0.000
Z89.5 Acquired absence of leg at or below knee
0.729 0.271 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.728 0.272 0.000
D36 Benign neoplasm of other and unspecified sites
0.727 0.273 0.000
Z33 Pregnant state, incidental
0.727 0.273 0.000
X60-X84 Intentional self-harm
0.726 0.274 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.726 0.274 0.000
Z43 Attention to artificial openings
0.726 0.274 0.000
Y42.5 Other oestrogens and progestogens
0.725 0.275 0.000
Z94 Transplanted organ and tissue status
0.724 0.276 0.000
S20-S29 Injuries to the thorax
0.723 0.276 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.723 0.277 0.000
D32 Benign neoplasm of meninges
0.722 0.278 0.000
Z92.8 Personal history of other medical treatment
0.721 0.279 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.721 0.279 0.000
J39 Other diseases of upper respiratory tract
0.720 0.280 0.000
Y44 Agents primarily affecting blood constituents
0.719 0.281 0.000
S80-S89 Injuries to the knee and lower leg
0.718 0.281 0.000
D16 Benign neoplasm of bone and articular cartilage
0.718 0.282 0.000
O00-O08 Pregnancy with abortive outcome
0.718 0.282 0.000
D27 Benign neoplasm of ovary
0.718 0.282 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z54 Convalescence
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
Z51.9 Medical care, unspecified
0.717 0.283 0.000
Z51.6 Desensitisation to allergens
0.717 0.283 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.715 0.284 0.000
Y83.3 Surgical operation with formation of external stoma
0.715 0.285 0.000
Y83.0 Surgical operation with transplant of whole organ
0.715 0.285 0.000
Z96.9 Presence of functional implant, unspecified
0.715 0.285 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.715 0.285 0.000
Z96.4 Presence of endocrine implants
0.715 0.285 0.000
Z96.3 Presence of artificial larynx
0.715 0.285 0.000
Z96.2 Presence of otological and audiological implants
0.715 0.285 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
S10-S19 Injuries to the neck
0.714 0.286 0.000
B99-B99 Other infectious diseases
0.714 0.286 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.714 0.286 0.000
B65-B83 Helminthiases
0.714 0.286 0.000
B50-B64 Protozoal diseases
0.714 0.286 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
B15-B19 Viral hepatitis
0.714 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.714 0.286 0.000
A80-A89 Viral infections of the central nervous system
0.714 0.286 0.000
A75-A79 Rickettsioses
0.714 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.714 0.286 0.000
A65-A69 Other spirochaetal diseases
0.714 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.714 0.286 0.000
A15-A19 Tuberculosis
0.714 0.286 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.714 0.286 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.714 0.286 0.000
C32 Malignant neoplasm of larynx
0.714 0.286 0.000
C31 Malignant neoplasm of accessory sinuses
0.714 0.286 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.714 0.286 0.000
C37 Malignant neoplasm of thymus
0.714 0.286 0.000
C33 Malignant neoplasm of trachea
0.714 0.286 0.000
T98 Sequelae of other and unspecified effects of external causes
0.712 0.288 0.000
C34.8 Overlapping lesion of bronchus and lung
0.712 0.288 0.000
C34.2 Middle lobe, bronchus or lung
0.712 0.288 0.000
Y59 Other and unspecified vaccines and biological substances
0.712 0.288 0.000
Y58 Bacterial vaccines
0.712 0.288 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.712 0.288 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.712 0.288 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.712 0.288 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.712 0.288 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.712 0.288 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.712 0.288 0.000
Y48 Anaesthetics and therapeutic gases
0.712 0.288 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.712 0.288 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.712 0.288 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.712 0.288 0.000
A48 Other bacterial diseases, not elsewhere classified
0.711 0.289 0.000
A44 Bartonellosis
0.711 0.289 0.000
A43 Nocardiosis
0.711 0.289 0.000
A42 Actinomycosis
0.711 0.289 0.000
A40 Streptococcal septicaemia
0.711 0.289 0.000
A39 Meningococcal infection
0.711 0.289 0.000
A37 Whooping cough
0.711 0.289 0.000
A36 Diphtheria
0.711 0.289 0.000
A32 Listeriosis
0.711 0.289 0.000
A31 Infection due to other mycobacteria
0.711 0.289 0.000
A30 Leprosy [Hansen's disease]
0.711 0.289 0.000
A46 Erysipelas
0.711 0.289 0.000
A38 Scarlet fever
0.711 0.289 0.000
A35 Other tetanus
0.711 0.289 0.000
A34 Obstetrical tetanus
0.711 0.289 0.000
A33 Tetanus neonatorum
0.711 0.289 0.000
E00-E07 Disorders of thyroid gland
0.710 0.290 0.000
C92 Myeloid leukaemia
0.710 0.290 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.710 0.290 0.000
T87 Complications peculiar to reattachment and amputation
0.710 0.290 0.000
V10-V19 Pedal cyclist injured in transport accident
0.708 0.292 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.708 0.292 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.708 0.292 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.708 0.292 0.000
A41.4 Septicaemia due to anaerobes
0.707 0.293 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.707 0.293 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.707 0.293 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.707 0.293 0.000
C95 Leukaemia of unspecified cell type
0.707 0.293 0.000
C94 Other leukaemias of specified cell type
0.707 0.293 0.000
C93 Monocytic leukaemia
0.707 0.293 0.000
C88 Malignant immunoproliferative diseases
0.707 0.293 0.000
C86 Other specified types of T/NK-cell lymphoma
0.707 0.293 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.707 0.293 0.000
C81 Hodgkin's disease
0.707 0.293 0.000
Z93.1 Gastrostomy status
0.706 0.293 0.000
Z93.6 Other artificial openings of urinary tract status
0.706 0.294 0.000
E87.2 Acidosis
0.706 0.294 0.000
Y84.9 Medical procedure, unspecified
0.705 0.294 0.000
Y84.7 Blood-sampling
0.705 0.294 0.000
Y84.5 Insertion of gastric or duodenal sound
0.705 0.294 0.000
Y84.4 Aspiration of fluid
0.705 0.294 0.000
Y84.3 Shock therapy
0.705 0.294 0.000
Y84.1 Kidney dialysis
0.705 0.294 0.000
Y40.9 Systemic antibiotic, unspecified
0.705 0.295 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.704 0.296 0.000
Z96.7 Presence of other bone and tendon implants
0.703 0.297 0.000
D50-D53 Nutritional anaemias
0.703 0.297 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.700 0.300 0.000
Z46.8 Fitting and adjustment of other specified devices
0.698 0.302 0.000
Y57 Other and unspecified drugs and medicaments
0.698 0.302 0.000
Z45.1 Adjustment and management of infusion pump
0.698 0.302 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.697 0.302 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.697 0.302 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.697 0.303 0.000
A41.8 Other specified septicaemia
0.697 0.303 0.000
E13 Other specified diabetes mellitus
0.697 0.303 0.000
C85.1 B-cell lymphoma, unspecified
0.696 0.304 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.696 0.304 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.695 0.305 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.695 0.305 0.000
J36 Peritonsillar abscess
0.695 0.305 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.694 0.306 0.000
D55-D59 Haemolytic anaemias
0.693 0.307 0.000
E40-E46 Malnutrition
0.693 0.307 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.693 0.307 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.693 0.307 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.693 0.307 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.693 0.307 0.000
Z50.1 Other physical therapy
0.692 0.308 0.000
N99-N99 Other disorders of the genitourinary system
0.691 0.309 0.000
C64-C68 Malignant neoplasms of urinary tract
0.691 0.309 0.000
Y43.9 Primarily systemic agent, unspecified
0.691 0.309 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.691 0.309 0.000
Y43.6 Enzymes, not elsewhere classified
0.691 0.309 0.000
Y43.5 Acidifying and alkalising agents
0.691 0.309 0.000
Y43.4 Immunosuppressive agents
0.691 0.309 0.000
Y43.2 Antineoplastic natural products
0.691 0.309 0.000
Y43.1 Antineoplastic antimetabolites
0.691 0.309 0.000
Y43.0 Antiallergic and antiemetic drugs
0.691 0.309 0.000
S90-S99 Injuries to the ankle and foot
0.688 0.311 0.000
D26 Other benign neoplasms of uterus
0.686 0.314 0.000
J22 Unspecified acute lower respiratory infection
0.686 0.314 0.000
A49.0 Staphylococcal infection, unspecified
0.685 0.315 0.000
C50.6 Axillary tail of breast
0.684 0.316 0.000
C50.0 Nipple and areola
0.684 0.316 0.000
Z85.6 Personal history of leukaemia
0.684 0.316 0.000
T78 Adverse effects, not elsewhere classified
0.682 0.318 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.681 0.319 0.000
N00-N08 Glomerular diseases
0.679 0.321 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.679 0.321 0.000
Z35 Supervision of high-risk pregnancy
0.678 0.322 0.000
E14 Unspecified diabetes mellitus
0.678 0.322 0.000
D04 Carcinoma in situ of skin
0.677 0.323 0.000
H65 Nonsuppurative otitis media
0.676 0.324 0.000
M20-M25 Other joint disorders
0.676 0.324 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.676 0.324 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.674 0.326 0.000
C50.3 Lower-inner quadrant of breast
0.674 0.326 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.674 0.326 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.673 0.327 0.000
D25.1 Intramural leiomyoma of uterus
0.673 0.327 0.000
Y40.0 Penicillins
0.672 0.328 0.000
C50.8 Overlapping lesion of breast
0.672 0.328 0.000
D75.8 Other specified diseases of blood and blood-forming organs
0.671 0.329 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.671 0.329 0.000
D74 Methaemoglobinaemia
0.671 0.329 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.671 0.329 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.671 0.329 0.000
D24 Benign neoplasm of breast
0.670 0.330 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.668 0.331 0.000
N30 Cystitis
0.668 0.332 0.000
C34.3 Lower lobe, bronchus or lung
0.667 0.332 0.000
J30 Vasomotor and allergic rhinitis
0.667 0.332 0.000
E50-E64 Other nutritional deficiencies
0.667 0.332 0.000
S06 Intracranial injury
0.667 0.333 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.667 0.333 0.000
N92.4 Excessive bleeding in the premenopausal period
0.666 0.334 0.000
Z88.2 Personal history of allergy to sulphonamides
0.665 0.335 0.000
Y40.8 Other systemic antibiotics
0.665 0.335 0.000
A00-A09 Intestinal infectious diseases
0.662 0.337 0.000
J81 Pulmonary oedema
0.662 0.338 0.000
Z93.0 Tracheostomy status
0.662 0.338 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.662 0.338 0.000
N18 Chronic renal failure
0.662 0.338 0.000
Z89.6 Acquired absence of leg above knee
0.661 0.339 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.661 0.339 0.000
Z50.0 Cardiac rehabilitation
0.660 0.340 0.000
C83.0 Small cell (diffuse)
0.660 0.340 0.000
S50-S59 Injuries to the elbow and forearm
0.659 0.341 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.658 0.342 0.000
J33.9 Nasal polyp, unspecified
0.658 0.342 0.000
T90 Sequelae of injuries of head
0.657 0.343 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.657 0.343 0.000
Z50.8 Care involving use of rehabilitation procedures
0.657 0.343 0.000
H91 Other hearing loss
0.657 0.343 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.654 0.345 0.000
N92.3 Ovulation bleeding
0.655 0.345 0.000
S70-S79 Injuries to the hip and thigh
0.654 0.346 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.654 0.346 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.654 0.346 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.654 0.346 0.000
Z46.4 Fitting and adjustment of orthodontic device
0.654 0.346 0.000
Z46.3 Fitting and adjustment of dental prosthetic device
0.654 0.346 0.000
Z46.2 Fitting and adjustment of other devices related to nervous system and special senses
0.654 0.346 0.000
Z46.1 Fitting and adjustment of hearing aid
0.654 0.346 0.000
Z46.0 Fitting and adjustment of spectacles and contact lenses
0.654 0.346 0.000
E10.1 With ketoacidosis
0.654 0.346 0.000
W18 Other fall on same level
0.653 0.346 0.000
W17 Other fall from one level to another
0.653 0.346 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.653 0.346 0.000
W15 Fall from cliff
0.653 0.346 0.000
W14 Fall from tree
0.653 0.346 0.000
W12 Fall on and from scaffolding
0.653 0.346 0.000
W11 Fall on and from ladder
0.653 0.346 0.000
W10 Fall on and from stairs and steps
0.653 0.346 0.000
W09 Fall involving playground equipment
0.653 0.346 0.000
W08 Fall involving other furniture
0.653 0.346 0.000
W06 Fall involving bed
0.653 0.346 0.000
W05 Fall involving wheelchair
0.653 0.346 0.000
W04 Fall while being carried or supported by other persons
0.653 0.346 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.653 0.346 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.653 0.346 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.653 0.346 0.000
W00 Fall on same level involving ice and snow
0.653 0.346 0.000
D31 Benign neoplasm of eye and adnexa
0.653 0.347 0.000
D30 Benign neoplasm of urinary organs
0.653 0.347 0.000
D29 Benign neoplasm of male genital organs
0.653 0.347 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.653 0.347 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.653 0.347 0.000
D19 Benign neoplasm of mesothelial tissue
0.653 0.347 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.653 0.347 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.652 0.348 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.652 0.348 0.000
C85.0 Lymphosarcoma
0.652 0.348 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.652 0.348 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.652 0.348 0.000
N92.5 Other specified irregular menstruation
0.651 0.349 0.000
Z40.9 Prophylactic surgery, unspecified
0.651 0.349 0.000
Z40.8 Other prophylactic surgery
0.651 0.349 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.650 0.350 0.000
Z39 Postpartum care and examination
0.650 0.350 0.000
A49.8 Other bacterial infections of unspecified site
0.649 0.351 0.000
N88 Other noninflammatory disorders of cervix uteri
0.649 0.351 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.648 0.352 0.000
Z92.9 Personal history of medical treatment, unspecified
0.648 0.352 0.000
Z92.5 Personal history of rehabilitation measures
0.648 0.352 0.000
Z92.0 Personal history of contraception
0.648 0.352 0.000
E12 Malnutrition-related diabetes mellitus
0.647 0.353 0.000
D60-D64 Aplastic and other anaemias
0.646 0.354 0.000
Z42 Follow-up care involving plastic surgery
0.645 0.355 0.000
C79 Secondary malignant neoplasm of other sites
0.644 0.356 0.000
Z51.2 Other chemotherapy
0.643 0.357 0.000
H80-H83 Diseases of inner ear
0.642 0.358 0.000
Y42.7 Androgens and anabolic congeners
0.641 0.359 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.641 0.359 0.000
H60-H62 Diseases of external ear
0.640 0.360 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.639 0.361 0.000
C51-C58 Malignant neoplasms of female genital organs
0.639 0.361 0.000
S00 Superficial injury of head
0.638 0.362 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.638 0.362 0.000
M25 Other joint disorders, not elsewhere classified
0.638 0.362 0.000
Z98.0 Intestinal bypass and anastomosis status
0.637 0.363 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.636 0.363 0.000
H72 Perforation of tympanic membrane
0.637 0.363 0.000
J20 Acute bronchitis
0.636 0.364 0.000
B49 Unspecified mycosis
0.634 0.365 0.000
T95 Sequelae of burns, corrosions and frostbite
0.634 0.366 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.634 0.366 0.000
T92 Sequelae of injuries of upper limb
0.634 0.366 0.000
T91 Sequelae of injuries of neck and trunk
0.634 0.366 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.634 0.366 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.634 0.366 0.000
Z50.5 Speech therapy
0.634 0.366 0.000
M70-M79 Other soft tissue disorders
0.633 0.367 0.000
D10 Benign neoplasm of mouth and pharynx
0.632 0.368 0.000
E85 Amyloidosis
0.632 0.368 0.000
E84 Cystic fibrosis
0.632 0.368 0.000
E79 Disorders of purine and pyrimidine metabolism
0.632 0.368 0.000
E77 Disorders of glycoprotein metabolism
0.632 0.368 0.000
E76 Disorders of glycosaminoglycan metabolism
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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