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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77282735
log Bayes Factor = 12.7192
Chromosome 7   position 45,090,949  (GRCh37) Explore rs77282735 on Ensembl!
Variant rs77282735 is part of Cluster X0032

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M45-M49 Spondylopathies
0.999 0.001 0.000
M50-M54 Other dorsopathies
0.999 0.001 0.000
M47 Spondylosis
0.999 0.001 0.000
Chapter II Neoplasms
0.998 0.002 0.000
M54 Dorsalgia
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
M47.9 Spondylosis, unspecified
0.996 0.004 0.000
D10-D36 Benign neoplasms
0.992 0.008 0.000
Chapter VIII Diseases of the ear and mastoid process
0.985 0.015 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.978 0.022 0.000
E65-E68 Obesity and other hyperalimentation
0.975 0.025 0.000
M47.8 Other spondylosis
0.966 0.034 0.000
E66 Obesity
0.959 0.041 0.000
H90-H95 Other disorders of ear
0.957 0.043 0.000
M54.3 Sciatica
0.957 0.043 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.953 0.047 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.936 0.064 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.934 0.066 0.000
Chapter V Mental and behavioural disorders
0.933 0.067 0.000
E66.9 Obesity, unspecified
0.932 0.068 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.931 0.069 0.000
C15-C26 Malignant neoplasms of digestive organs
0.929 0.071 0.000
E20-E35 Disorders of other endocrine glands
0.929 0.071 0.000
K70-K77 Diseases of liver
0.928 0.072 0.000
Chapter XX External causes of morbidity and mortality
0.923 0.077 0.000
E10-E14 Diabetes mellitus
0.922 0.078 0.000
M47.86 Other spondylosis (Lumbar region)
0.920 0.080 0.000
Chapter VI Diseases of the nervous system
0.912 0.088 0.000
D22 Melanocytic naevi
0.910 0.090 0.000
T81 Complications of procedures, not elsewhere classified
0.909 0.091 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.906 0.094 0.000
E00-E07 Disorders of thyroid gland
0.903 0.097 0.000
K40-K46 Hernia
0.899 0.101 0.000
M54.1 Radiculopathy
0.899 0.101 0.000
D25 Leiomyoma of uterus
0.897 0.103 0.000
M54.4 Lumbago with sciatica
0.896 0.104 0.000
K50-K52 Noninfective enteritis and colitis
0.894 0.106 0.000
M20-M25 Other joint disorders
0.892 0.108 0.000
S50-S59 Injuries to the elbow and forearm
0.891 0.109 0.000
M54.2 Cervicalgia
0.889 0.111 0.000
C20 Malignant neoplasm of rectum
0.889 0.111 0.000
Chapter I Certain infectious and parasitic diseases
0.887 0.113 0.000
K90-K93 Other diseases of the digestive system
0.886 0.114 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.880 0.120 0.000
S40-S49 Injuries to the shoulder and upper arm
0.879 0.121 0.000
M54.36 Sciatica (Lumbar region)
0.875 0.125 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.871 0.129 0.000
H93 Other disorders of ear, not elsewhere classified
0.871 0.129 0.000
D25.0 Submucous leiomyoma of uterus
0.866 0.134 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.865 0.135 0.000
M54.5 Low back pain
0.861 0.139 0.000
K52 Other non-infective gastro-enteritis and colitis
0.859 0.141 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.859 0.141 0.000
D24 Benign neoplasm of breast
0.859 0.141 0.000
Chapter XXII Codes for special purposes
0.856 0.144 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.854 0.146 0.000
K74 Fibrosis and cirrhosis of liver
0.853 0.147 0.000
D22.5 Melanocytic naevi of trunk
0.849 0.151 0.000
M23 Internal derangement of knee
0.849 0.151 0.000
D00-D09 In situ neoplasms
0.847 0.153 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.847 0.153 0.000
M05-M14 Inflammatory polyarthropathies
0.845 0.155 0.000
D17 Benign lipomatous neoplasm
0.844 0.156 0.000
M47.82 Other spondylosis (Cervical region)
0.844 0.156 0.000
H80-H83 Diseases of inner ear
0.841 0.159 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.841 0.159 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.841 0.159 0.000
E66.8 Other obesity
0.840 0.160 0.000
M51 Other intervertebral disk disorders
0.840 0.160 0.000
M80-M85 Disorders of bone density and structure
0.839 0.161 0.000
D10 Benign neoplasm of mouth and pharynx
0.838 0.162 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.837 0.163 0.000
E03 Other hypothyroidism
0.836 0.164 0.000
S60-S69 Injuries to the wrist and hand
0.836 0.164 0.000
F30-F39 Mood [affective] disorders
0.836 0.164 0.000
H91 Other hearing loss
0.835 0.165 0.000
E10 Insulin-dependent diabetes mellitus
0.830 0.170 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.829 0.171 0.000
E23 Hypofunction and other disorders of pituitary gland
0.826 0.174 0.000
M86-M90 Other osteopathies
0.824 0.176 0.000
M54.39 Sciatica (Site unspecified)
0.823 0.177 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.823 0.177 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.821 0.179 0.000
K81 Cholecystitis
0.821 0.179 0.000
K86 Other diseases of pancreas
0.821 0.179 0.000
K42 Umbilical hernia
0.819 0.181 0.000
D32 Benign neoplasm of meninges
0.815 0.185 0.000
M54.22 Cervicalgia (Cervical region)
0.811 0.189 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.810 0.190 0.000
H93.1 Tinnitus
0.809 0.191 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.808 0.192 0.000
K83 Other diseases of biliary tract
0.805 0.195 0.000
M47.89 Other spondylosis (Site unspecified)
0.802 0.198 0.000
W00-W19 Falls
0.802 0.198 0.000
Chapter IX Diseases of the circulatory system
0.802 0.198 0.000
S52 Fracture of forearm
0.800 0.200 0.000
F33 Recurrent depressive disorder
0.798 0.202 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.796 0.204 0.000
K92 Other diseases of digestive system
0.794 0.206 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.793 0.207 0.000
D26 Other benign neoplasms of uterus
0.792 0.208 0.000
M23.3 Other meniscus derangements
0.792 0.208 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.790 0.210 0.000
C17 Malignant neoplasm of small intestine
0.790 0.210 0.000
M46 Other inflammatory spondylopathies
0.789 0.211 0.000
E03.9 Hypothyroidism, unspecified
0.788 0.212 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.787 0.213 0.000
E11 Non-insulin-dependent diabetes mellitus
0.786 0.214 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.786 0.214 0.000
H92 Otalgia and effusion of ear
0.784 0.216 0.000
I30-I52 Other forms of heart disease
0.784 0.216 0.000
M48 Other spondylopathies
0.782 0.218 0.000
K44 Diaphragmatic hernia
0.781 0.219 0.000
H80 Otosclerosis
0.779 0.220 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.775 0.225 0.000
D46 Myelodysplastic syndromes
0.774 0.226 0.000
M54.12 Radiculopathy (Cervical region)
0.774 0.226 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.769 0.230 0.000
S80-S89 Injuries to the knee and lower leg
0.767 0.233 0.000
B35-B49 Mycoses
0.767 0.233 0.000
D45 Polycythaemia vera
0.764 0.236 0.000
D11 Benign neoplasm of major salivary glands
0.763 0.237 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.763 0.237 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.762 0.238 0.000
H65-H75 Diseases of middle ear and mastoid
0.761 0.239 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.761 0.239 0.000
M54.37 Sciatica (Lumbosacral region)
0.758 0.242 0.000
K74.3 Primary biliary cirrhosis
0.758 0.242 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.757 0.242 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.756 0.244 0.000
C51-C58 Malignant neoplasms of female genital organs
0.756 0.244 0.000
M84 Disorders of continuity of bone
0.752 0.248 0.000
D22.4 Melanocytic naevi of scalp and neck
0.751 0.249 0.000
S42 Fracture of shoulder and upper arm
0.750 0.249 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.749 0.251 0.000
D30 Benign neoplasm of urinary organs
0.749 0.251 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.748 0.252 0.000
H91.9 Hearing loss, unspecified
0.747 0.253 0.000
S90-S99 Injuries to the ankle and foot
0.746 0.254 0.000
K08 Other disorders of teeth and supporting structures
0.746 0.254 0.000
M54.56 Low back pain (Lumbar region)
0.745 0.255 0.000
S68 Traumatic amputation of wrist and hand
0.745 0.255 0.000
M23.8 Other internal derangements of knee
0.744 0.256 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.744 0.256 0.000
M65-M68 Disorders of synovium and tendon
0.744 0.256 0.000
M54.6 Pain in thoracic spine
0.743 0.257 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.742 0.258 0.000
E27 Other disorders of adrenal gland
0.741 0.259 0.000
H90 Conductive and sensorineural hearing loss
0.741 0.259 0.000
K76 Other diseases of liver
0.741 0.259 0.000
E50-E64 Other nutritional deficiencies
0.740 0.260 0.000
M54.9 Dorsalgia, unspecified
0.740 0.260 0.000
M21 Other acquired deformities of limbs
0.739 0.261 0.000
M00-M03 Infectious arthropathies
0.739 0.261 0.000
M10 Gout
0.738 0.262 0.000
T79-T79 Certain early complications of trauma
0.737 0.263 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.736 0.264 0.000
M70-M79 Other soft tissue disorders
0.736 0.264 0.000
M40-M43 Deforming dorsopathies
0.736 0.264 0.000
H80.9 Otosclerosis, unspecified
0.736 0.264 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.736 0.264 0.000
H60-H62 Diseases of external ear
0.735 0.265 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.735 0.265 0.000
K46 Unspecified abdominal hernia
0.734 0.266 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.734 0.266 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.734 0.266 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.733 0.267 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.733 0.267 0.000
M91-M94 Chondropathies
0.733 0.267 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.730 0.270 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.729 0.270 0.000
D10.3 Other and unspecified parts of mouth
0.726 0.274 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.725 0.275 0.000
E29 Testicular dysfunction
0.725 0.275 0.000
K75 Other inflammatory liver diseases
0.725 0.275 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.725 0.275 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.724 0.275 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.724 0.276 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.723 0.277 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.723 0.277 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.723 0.277 0.000
M54.57 Low back pain (Lumbosacral region)
0.722 0.278 0.000
K11 Diseases of salivary glands
0.722 0.278 0.000
K65-K67 Diseases of peritoneum
0.722 0.278 0.000
E28 Ovarian dysfunction
0.722 0.278 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.722 0.278 0.000
E23.0 Hypopituitarism
0.722 0.278 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.722 0.278 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.721 0.279 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.720 0.280 0.000
M50 Cervical disk disorders
0.720 0.280 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.720 0.280 0.000
K90 Intestinal malabsorption
0.718 0.282 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.718 0.282 0.000
B15-B19 Viral hepatitis
0.718 0.282 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M49 Spondylopathies in diseases classified elsewhere
0.717 0.283 0.000
M53 Other dorsopathies, not elsewhere classified
0.716 0.284 0.000
M47.1 Other spondylosis with myelopathy
0.716 0.284 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.716 0.284 0.000
F10.1 Harmful use
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
M54.8 Other dorsalgia
0.715 0.284 0.000
M54.0 Panniculitis affecting regions of neck and back
0.715 0.284 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.714 0.286 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.714 0.286 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.714 0.286 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.714 0.286 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.714 0.286 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.714 0.286 0.000
Y00-Y09 Assault
0.714 0.286 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.714 0.286 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.712 0.288 0.000
D31 Benign neoplasm of eye and adnexa
0.711 0.289 0.000
D29 Benign neoplasm of male genital organs
0.711 0.289 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.711 0.289 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.711 0.289 0.000
D19 Benign neoplasm of mesothelial tissue
0.711 0.289 0.000
D16 Benign neoplasm of bone and articular cartilage
0.711 0.289 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.711 0.289 0.000
I44 Atrioventricular and left bundle-branch block
0.711 0.289 0.000
F33.9 Recurrent depressive disorder, unspecified
0.710 0.290 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.709 0.291 0.000
S52.0 Fracture of upper end of ulna
0.709 0.291 0.000
K41 Femoral hernia
0.707 0.292 0.000
K74.5 Biliary cirrhosis, unspecified
0.707 0.292 0.000
E40-E46 Malnutrition
0.707 0.293 0.000
K86.8 Other specified diseases of pancreas
0.707 0.293 0.000
E10.9 Without complications
0.706 0.294 0.000
E13 Other specified diabetes mellitus
0.706 0.294 0.000
K83.1 Obstruction of bile duct
0.706 0.294 0.000
G70-G73 Diseases of myoneural junction and muscle
0.703 0.297 0.000
D04 Carcinoma in situ of skin
0.702 0.298 0.000
S41 Open wound of shoulder and upper arm
0.701 0.299 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.701 0.299 0.000
M31 Other necrotising vasculopathies
0.701 0.299 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.701 0.299 0.000
T87 Complications peculiar to reattachment and amputation
0.701 0.299 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.701 0.299 0.000
D03 Melanoma in situ
0.701 0.299 0.000
K81.9 Cholecystitis, unspecified
0.701 0.299 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.699 0.301 0.000
E67 Other hyperalimentation
0.699 0.301 0.000
E68 Sequelae of hyperalimentation
0.699 0.301 0.000
E65 Localised adiposity
0.699 0.301 0.000
M51.2 Other specified intervertebral disk displacement
0.699 0.301 0.000
C25 Malignant neoplasm of pancreas
0.699 0.301 0.000
I44.0 Atrioventricular block, first degree
0.698 0.302 0.000
T66-T78 Other and unspecified effects of external causes
0.698 0.302 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.697 0.303 0.000
K01 Embedded and impacted teeth
0.696 0.304 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.696 0.304 0.000
S52.1 Fracture of upper end of radius
0.695 0.305 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.694 0.306 0.000
S51 Open wound of forearm
0.693 0.307 0.000
K52.1 Toxic gastro-enteritis and colitis
0.693 0.307 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.693 0.307 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.693 0.307 0.000
M47.84 Other spondylosis (Thoracic region)
0.693 0.307 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.693 0.307 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.693 0.307 0.000
D22.0 Melanocytic naevi of lip
0.693 0.307 0.000
O60-O75 Complications of labour and delivery
0.692 0.308 0.000
D25.2 Subserosal leiomyoma of uterus
0.691 0.309 0.000
M54.16 Radiculopathy (Lumbar region)
0.691 0.309 0.000
M47.2 Other spondylosis with radiculopathy
0.689 0.311 0.000
C64-C68 Malignant neoplasms of urinary tract
0.688 0.311 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.688 0.312 0.000
T18 Foreign body in alimentary tract
0.688 0.312 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.687 0.313 0.000
E66.1 Drug-induced obesity
0.687 0.313 0.000
E66.0 Obesity due to excess calories
0.687 0.313 0.000
T86 Failure and rejection of transplanted organs and tissues
0.687 0.313 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.686 0.313 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.686 0.313 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.686 0.314 0.000
M54.35 Sciatica (Thoracolumbar region)
0.686 0.314 0.000
M54.34 Sciatica-Thoracic
0.686 0.314 0.000
M54.33 Sciatica-Cervicothoracic
0.686 0.314 0.000
M54.32 Sciatica-Cervical
0.686 0.314 0.000
M54.31 Sciatica-Occipit-atl-axl
0.686 0.314 0.000
M54.30 Sciatica (Multiple sites in spine)
0.686 0.314 0.000
K12 Stomatitis and related lesions
0.685 0.315 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.684 0.316 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.683 0.317 0.000
I42 Cardiomyopathy
0.683 0.317 0.000
W20-W49 Exposure to inanimate mechanical forces
0.682 0.318 0.000
S70-S79 Injuries to the hip and thigh
0.681 0.319 0.000
B37 Candidiasis
0.681 0.319 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.681 0.319 0.000
I34 Nonrheumatic mitral valve disorders
0.681 0.319 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.680 0.320 0.000
D09 Carcinoma in situ of other and unspecified sites
0.678 0.322 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.677 0.323 0.000
S40 Superficial injury of shoulder and upper arm
0.677 0.323 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.677 0.323 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.676 0.323 0.000
I27 Other pulmonary heart diseases
0.677 0.323 0.000
K92.0 Haematemesis
0.676 0.324 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.676 0.324 0.000
M90 Osteopathies in diseases classified elsewhere
0.676 0.324 0.000
E10.5 With peripheral circulatory complications
0.676 0.324 0.000
D32.0 Cerebral meninges
0.673 0.327 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.673 0.327 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.673 0.327 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.672 0.328 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.672 0.328 0.000
T88.4 Failed or difficult intubation
0.672 0.328 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.672 0.328 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.670 0.330 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.670 0.330 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.670 0.330 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.670 0.330 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.670 0.330 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.670 0.330 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.670 0.330 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.670 0.330 0.000
M05 Seropositive rheumatoid arthritis
0.670 0.330 0.000
T91 Sequelae of injuries of neck and trunk
0.669 0.331 0.000
F99-F99 Unspecified mental disorder
0.669 0.331 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.669 0.331 0.000
F80-F89 Disorders of psychological development
0.669 0.331 0.000
F70-F79 Mental retardation
0.669 0.331 0.000
F60-F69 Disorders of adult personality and behaviour
0.669 0.331 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.669 0.331 0.000
C18 Malignant neoplasm of colon
0.669 0.331 0.000
B95-B98 Bacterial, viral and other infectious agents
0.669 0.331 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.668 0.332 0.000
L03 Cellulitis
0.668 0.332 0.000
E22 Hyperfunction of pituitary gland
0.667 0.333 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.667 0.333 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.667 0.333 0.000
E06 Thyroiditis
0.666 0.334 0.000
T17 Foreign body in respiratory tract
0.666 0.334 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.666 0.334 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.666 0.334 0.000
C21 Malignant neoplasm of anus and anal canal
0.666 0.334 0.000
C23 Malignant neoplasm of gallbladder
0.666 0.334 0.000
D34 Benign neoplasm of thyroid gland
0.666 0.334 0.000
C91 Lymphoid leukaemia
0.666 0.334 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.666 0.334 0.000
E34 Other endocrine disorders
0.666 0.334 0.000
E32 Diseases of thymus
0.666 0.334 0.000
E31 Polyglandular dysfunction
0.666 0.334 0.000
E30 Disorders of puberty, not elsewhere classified
0.666 0.334 0.000
E26 Hyperaldosteronism
0.666 0.334 0.000
E25 Adrenogenital disorders
0.666 0.334 0.000
E24 Cushing's syndrome
0.666 0.334 0.000
E20 Hypoparathyroidism
0.666 0.334 0.000
K77 Liver disorders in diseases classified elsewhere
0.666 0.334 0.000
K73 Chronic hepatitis, not elsewhere classified
0.666 0.334 0.000
K72 Hepatic failure, not elsewhere classified
0.666 0.334 0.000
K71 Toxic liver disease
0.666 0.334 0.000
S62 Fracture at wrist and hand level
0.666 0.334 0.000
H92.0 Otalgia
0.665 0.334 0.000
S20-S29 Injuries to the thorax
0.664 0.335 0.000
M10.9 Gout, unspecified
0.662 0.338 0.000
D36 Benign neoplasm of other and unspecified sites
0.662 0.338 0.000
I05-I09 Chronic rheumatic heart diseases
0.662 0.338 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.662 0.338 0.000
M35 Other systemic involvement of connective tissue
0.662 0.338 0.000
Y35-Y36 Legal intervention and operations of war
0.661 0.338 0.000
Y10-Y34 Event of undetermined intent
0.661 0.338 0.000
X85-X99 Assault
0.661 0.338 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.661 0.338 0.000
X50-X57 Overexertion, travel and privation
0.661 0.338 0.000
X30-X39 Exposure to forces of nature
0.661 0.338 0.000
X20-X29 Contact with venomous animals and plants
0.661 0.338 0.000
X10-X19 Contact with heat and hot substances
0.661 0.338 0.000
X00-X09 Exposure to smoke, fire and flames
0.661 0.338 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.661 0.338 0.000
W75-W84 Other accidental threats to breathing
0.661 0.338 0.000
W65-W74 Accidental drowning and submersion
0.661 0.338 0.000
W50-W64 Exposure to animate mechanical forces
0.661 0.338 0.000
V98-V99 Other and unspecified transport accidents
0.661 0.338 0.000
V95-V97 Air and space transport accidents
0.661 0.338 0.000
V90-V94 Water transport accidents
0.661 0.338 0.000
V80-V89 Other land transport accidents
0.661 0.338 0.000
V70-V79 Bus occupant injured in transport accident
0.661 0.338 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.661 0.338 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.661 0.338 0.000
V40-V49 Car occupant injured in transport accident
0.661 0.338 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.661 0.338 0.000
V01-V09 Pedestrian injured in transport accident
0.661 0.338 0.000
K07 Dentofacial anomalies [including malocclusion]
0.661 0.339 0.000
M45 Ankylosing spondylitis
0.661 0.339 0.000
E12 Malnutrition-related diabetes mellitus
0.661 0.339 0.000
E23.2 Diabetes insipidus
0.661 0.339 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.661 0.339 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.660 0.340 0.000
K86.3 Pseudocyst of pancreas
0.660 0.340 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.660 0.340 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.660 0.340 0.000
X60-X84 Intentional self-harm
0.659 0.340 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.659 0.340 0.000
E11.5 With peripheral circulatory complications
0.659 0.341 0.000
K85 Acute pancreatitis
0.659 0.341 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.659 0.341 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.658 0.342 0.000
T90 Sequelae of injuries of head
0.656 0.343 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.656 0.344 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.654 0.346 0.000
D27 Benign neoplasm of ovary
0.653 0.347 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.653 0.347 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.653 0.347 0.000
M24 Other specific joint derangements
0.652 0.348 0.000
D22.9 Melanocytic naevi, unspecified
0.652 0.348 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.652 0.348 0.000
K08.3 Retained dental root
0.652 0.348 0.000
T81.9 Unspecified complication of procedure
0.652 0.348 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.652 0.348 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.652 0.348 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.652 0.348 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.652 0.348 0.000
I49 Other cardiac arrhythmias
0.652 0.348 0.000
K81.1 Chronic cholecystitis
0.649 0.350 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.649 0.351 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.648 0.352 0.000
U80 Agent resistant to penicillin and related antibiotics
0.648 0.352 0.000
A00-A09 Intestinal infectious diseases
0.648 0.352 0.000
B37.0 Candidal stomatitis
0.648 0.352 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.648 0.352 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.648 0.352 0.000
E00 Congenital iodine-deficiency syndrome
0.648 0.352 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.648 0.352 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.647 0.353 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.647 0.353 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.646 0.354 0.000
D14.0 Middle ear, nasal cavity and accessory sinuses
0.646 0.354 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.645 0.355 0.000
K45 Other abdominal hernia
0.645 0.355 0.000
D23 Other benign neoplasms of skin
0.645 0.355 0.000
M54.19 Radiculopathy (Site unspecified)
0.644 0.355 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.644 0.355 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.644 0.355 0.000
M54.14 Radiculopathy (Thoracic region)
0.644 0.355 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.644 0.355 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.644 0.355 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.644 0.355 0.000
C83.1 Small cleaved cell (diffuse)
0.644 0.356 0.000
D26.0 Cervix uteri
0.644 0.356 0.000
K13 Other diseases of lip and oral mucosa
0.644 0.356 0.000
W19 Unspecified fall
0.644 0.356 0.000
S52.00 Fracture of upper end of ulna (closed)
0.644 0.356 0.000
K83.0 Cholangitis
0.643 0.357 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.642 0.358 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.642 0.358 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.642 0.358 0.000
M54.44 Lumbago with sciatica-Thoracic
0.642 0.358 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.642 0.358 0.000
M54.42 Lumbago with sciatica-Cervical
0.642 0.358 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.642 0.358 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.642 0.358 0.000
C83.0 Small cell (diffuse)
0.642 0.358 0.000
C17.0 Duodenum
0.641 0.359 0.000
E10.4 With neurological complications
0.641 0.359 0.000
M85 Other disorders of bone density and structure
0.641 0.359 0.000
M51.8 Other specified intervertebral disk disorders
0.640 0.360 0.000
C17.9 Small intestine, unspecified
0.640 0.360 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.639 0.361 0.000
M34 Systemic sclerosis
0.639 0.361 0.000
M33 Dermatopolymyositis
0.639 0.361 0.000
M32 Systemic lupus erythematosus
0.639 0.361 0.000
M30 Polyarteritis nodosa and related conditions
0.639 0.361 0.000
K92.8 Other specified diseases of digestive system
0.639 0.361 0.000
S59 Other and unspecified injuries of forearm
0.639 0.361 0.000
S58 Traumatic amputation of forearm
0.639 0.361 0.000
S57 Crushing injury of forearm
0.639 0.361 0.000
S56 Injury of muscle and tendon at forearm level
0.639 0.361 0.000
S55 Injury of blood vessels at forearm level
0.639 0.361 0.000
S54 Injury of nerves at forearm level
0.639 0.361 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.639 0.361 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.638 0.361 0.000
G57 Mononeuropathies of lower limb
0.638 0.362 0.000
V20-V29 Motorcycle rider injured in transport accident
0.638 0.362 0.000
D13.2 Duodenum
0.638 0.362 0.000
M54.29 Cervicalgia-Site unspe
0.637 0.362 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.637 0.362 0.000
M54.27 Cervicalgia-Lumbosacral
0.637 0.362 0.000
M54.26 Cervicalgia-Lumbar
0.637 0.362 0.000
M54.25 Cervicalgia-Thoracolumbar
0.637 0.362 0.000
M54.24 Cervicalgia-Thoracic
0.637 0.362 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.637 0.362 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.637 0.362 0.000
M54.20 Cervicalgia-Mult site
0.637 0.362 0.000
M86 Osteomyelitis
0.637 0.363 0.000
I46 Cardiac arrest
0.637 0.363 0.000
E10.3 With ophthalmic complications
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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