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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77308085
log Bayes Factor = 20.0947
Chromosome 7   position 116,216,661  (GRCh37) Explore rs77308085 on Ensembl!
Variant rs77308085 is part of Cluster X0274

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N30-N39 Other diseases of urinary system
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
N40-N51 Diseases of male genital organs
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
J09-J18 Influenza and pneumonia
0.998 0.002 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.997 0.003 0.000
J18 Pneumonia, organism unspecified
0.995 0.005 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.993 0.007 0.000
N40 Hyperplasia of prostate
0.992 0.008 0.000
J18.9 Pneumonia, unspecified
0.992 0.008 0.000
M05-M14 Inflammatory polyarthropathies
0.989 0.011 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.988 0.012 0.000
J90-J94 Other diseases of pleura
0.987 0.013 0.000
I60-I69 Cerebrovascular diseases
0.987 0.013 0.000
N32 Other disorders of bladder
0.985 0.015 0.000
M06 Other rheumatoid arthritis
0.984 0.016 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.983 0.017 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.982 0.018 0.000
M06.9 Rheumatoid arthritis, unspecified
0.981 0.019 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.981 0.019 0.000
N30 Cystitis
0.981 0.019 0.000
N36 Other disorders of urethra
0.978 0.022 0.000
Chapter VI Diseases of the nervous system
0.976 0.024 0.000
J90 Pleural effusion, not elsewhere classified
0.976 0.024 0.000
Chapter VIII Diseases of the ear and mastoid process
0.973 0.027 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.969 0.031 0.000
N48 Other disorders of penis
0.968 0.032 0.000
Chapter XX External causes of morbidity and mortality
0.967 0.033 0.000
R79 Other abnormal findings of blood chemistry
0.964 0.036 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.964 0.036 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.963 0.037 0.000
H30-H36 Disorders of choroid and retina
0.962 0.038 0.000
Chapter II Neoplasms
0.959 0.041 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.959 0.041 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.957 0.043 0.000
N32.8 Other specified disorders of bladder
0.956 0.044 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.955 0.045 0.000
N10-N16 Renal tubulo-interstitial diseases
0.949 0.051 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.949 0.051 0.000
G90-G99 Other disorders of the nervous system
0.948 0.052 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.947 0.053 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.944 0.056 0.000
C79 Secondary malignant neoplasm of other sites
0.944 0.056 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.942 0.058 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.939 0.061 0.000
N36.8 Other specified disorders of urethra
0.939 0.061 0.000
M20-M25 Other joint disorders
0.938 0.062 0.000
N30.9 Cystitis, unspecified
0.937 0.063 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.935 0.065 0.000
H04 Disorders of lachrymal system
0.929 0.071 0.000
H90-H95 Other disorders of ear
0.928 0.072 0.000
E00-E07 Disorders of thyroid gland
0.920 0.080 0.000
I67 Other cerebrovascular diseases
0.912 0.088 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.904 0.096 0.000
R94 Abnormal results of function studies
0.899 0.101 0.000
I30-I52 Other forms of heart disease
0.898 0.102 0.000
H33 Retinal detachments and breaks
0.896 0.104 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.896 0.104 0.000
H90 Conductive and sensorineural hearing loss
0.896 0.104 0.000
I71 Aortic aneurysm and dissection
0.895 0.105 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.895 0.105 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.893 0.107 0.000
I63 Cerebral infarction
0.893 0.107 0.000
D50-D53 Nutritional anaemias
0.892 0.108 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.892 0.108 0.000
J81 Pulmonary oedema
0.890 0.110 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.888 0.112 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.885 0.115 0.000
N48.8 Other specified disorders of penis
0.885 0.115 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.881 0.119 0.000
N30.1 Interstitial cystitis (chronic)
0.881 0.119 0.000
S00-S09 Injuries to the head
0.880 0.120 0.000
N30.8 Other cystitis
0.879 0.121 0.000
E70-E90 Metabolic disorders
0.878 0.122 0.000
H43-H45 Disorders of vitreous body and globe
0.874 0.126 0.000
H35 Other retinal disorders
0.872 0.128 0.000
S40-S49 Injuries to the shoulder and upper arm
0.869 0.131 0.000
I67.8 Other specified cerebrovascular diseases
0.869 0.131 0.000
R29.6 Tendency to fall, not elsewhere classified
0.868 0.132 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.868 0.132 0.000
D51 Vitamin B12 deficiency anaemia
0.866 0.134 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.865 0.135 0.000
D80-D89 Certain disorders involving the immune mechanism
0.864 0.136 0.000
J40-J47 Chronic lower respiratory diseases
0.860 0.140 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.858 0.142 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.858 0.142 0.000
W00-W19 Falls
0.858 0.142 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.857 0.143 0.000
G93 Other disorders of brain
0.856 0.144 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.855 0.145 0.000
H02 Other disorders of eyelid
0.853 0.147 0.000
N13 Obstructive and reflux uropathy
0.852 0.148 0.000
M60-M63 Disorders of muscles
0.851 0.149 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.851 0.149 0.000
J92 Pleural plaque
0.849 0.151 0.000
H80-H83 Diseases of inner ear
0.847 0.153 0.000
C78.7 Secondary malignant neoplasm of liver
0.845 0.155 0.000
J95-J99 Other diseases of the respiratory system
0.845 0.155 0.000
M34 Systemic sclerosis
0.842 0.158 0.000
J18.1 Lobar pneumonia, unspecified
0.841 0.159 0.000
C78.0 Secondary malignant neoplasm of lung
0.841 0.159 0.000
N32.9 Bladder disorder, unspecified
0.841 0.159 0.000
M35 Other systemic involvement of connective tissue
0.838 0.162 0.000
N42 Other disorders of prostate
0.836 0.164 0.000
E86 Volume depletion
0.834 0.166 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.833 0.167 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.832 0.168 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.830 0.170 0.000
H90.5 Sensorineural hearing loss, unspecified
0.829 0.171 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.829 0.171 0.000
M07 Psoriatic and enteropathic arthropathies
0.829 0.171 0.000
H33.0 Retinal detachment with retinal break
0.827 0.173 0.000
I60 Subarachnoid haemorrhage
0.827 0.173 0.000
J60-J70 Lung diseases due to external agents
0.825 0.175 0.000
M91-M94 Chondropathies
0.822 0.178 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.820 0.180 0.000
H02.8 Other specified disorders of eyelid
0.818 0.182 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.816 0.184 0.000
S02 Fracture of skull and facial bones
0.814 0.186 0.000
N32.0 Bladder-neck obstruction
0.814 0.186 0.000
M50-M54 Other dorsopathies
0.814 0.186 0.000
R20 Disturbances of skin sensation
0.814 0.186 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.813 0.187 0.000
I27 Other pulmonary heart diseases
0.813 0.187 0.000
N36.2 Urethral caruncle
0.813 0.187 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.812 0.188 0.000
D45 Polycythaemia vera
0.812 0.188 0.000
D75 Other diseases of blood and blood-forming organs
0.810 0.190 0.000
N48.1 Balanoposthitis
0.809 0.191 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.809 0.191 0.000
S70-S79 Injuries to the hip and thigh
0.808 0.192 0.000
N48.0 Leukoplakia of penis
0.807 0.193 0.000
I49 Other cardiac arrhythmias
0.806 0.194 0.000
Chapter I Certain infectious and parasitic diseases
0.805 0.195 0.000
H92 Otalgia and effusion of ear
0.803 0.197 0.000
G40-G47 Episodic and paroxysmal disorders
0.802 0.198 0.000
S90-S99 Injuries to the ankle and foot
0.798 0.202 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.798 0.202 0.000
N36.0 Urethral fistula
0.797 0.203 0.000
I63.9 Cerebral infarction, unspecified
0.796 0.204 0.000
V80-V89 Other land transport accidents
0.796 0.204 0.000
H53-H54 Visual disturbances and blindness
0.795 0.205 0.000
I44 Atrioventricular and left bundle-branch block
0.794 0.206 0.000
E05.9 Thyrotoxicosis, unspecified
0.793 0.207 0.000
R20.2 Paraesthesia of skin
0.791 0.209 0.000
Chapter XI Diseases of the digestive system
0.789 0.211 0.000
K70-K77 Diseases of liver
0.786 0.214 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.786 0.214 0.000
N00-N08 Glomerular diseases
0.786 0.214 0.000
J80 Adult respiratory distress syndrome
0.785 0.215 0.000
N25-N29 Other disorders of kidney and ureter
0.784 0.216 0.000
N50 Other disorders of male genital organs
0.783 0.217 0.000
J43 Emphysema
0.782 0.218 0.000
R94.5 Abnormal results of liver function studies
0.782 0.218 0.000
M35.3 Polymyalgia rheumatica
0.781 0.219 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.781 0.219 0.000
W20-W49 Exposure to inanimate mechanical forces
0.781 0.219 0.000
H65-H75 Diseases of middle ear and mastoid
0.780 0.220 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.777 0.223 0.000
G30-G32 Other degenerative diseases of the nervous system
0.777 0.223 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.776 0.224 0.000
J84 Other interstitial pulmonary diseases
0.775 0.225 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.774 0.226 0.000
D60-D64 Aplastic and other anaemias
0.773 0.227 0.000
T79-T79 Certain early complications of trauma
0.773 0.227 0.000
J40 Bronchitis, not specified as acute or chronic
0.772 0.228 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.772 0.228 0.000
E04 Other non-toxic goitre
0.771 0.229 0.000
I63.8 Other cerebral infarction
0.770 0.230 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.767 0.233 0.000
H90.3 Sensorineural hearing loss, bilateral
0.766 0.234 0.000
J98 Other respiratory disorders
0.764 0.236 0.000
H52 Disorders of refraction and accommodation
0.763 0.237 0.000
I77 Other disorders of arteries and arterioles
0.762 0.238 0.000
I31 Other diseases of pericardium
0.761 0.239 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.760 0.240 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.758 0.242 0.000
T66-T78 Other and unspecified effects of external causes
0.758 0.242 0.000
R27 Other lack of coordination
0.756 0.244 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.756 0.244 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.756 0.244 0.000
H34 Retinal vascular occlusions
0.756 0.244 0.000
M86-M90 Other osteopathies
0.754 0.246 0.000
G93.3 Postviral fatigue syndrome
0.753 0.247 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.753 0.247 0.000
I36 Nonrheumatic tricuspid valve disorders
0.752 0.248 0.000
N48.9 Disorder of penis, unspecified
0.750 0.250 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.749 0.251 0.000
D75.1 Secondary polycythaemia
0.749 0.251 0.000
H35.8 Other specified retinal disorders
0.749 0.251 0.000
H10-H13 Disorders of conjunctiva
0.749 0.251 0.000
R74 Abnormal serum enzyme levels
0.749 0.251 0.000
N11 Chronic tubulo-interstitial nephritis
0.749 0.251 0.000
E50-E64 Other nutritional deficiencies
0.748 0.252 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.748 0.252 0.000
E20-E35 Disorders of other endocrine glands
0.748 0.252 0.000
B35-B49 Mycoses
0.748 0.252 0.000
H35.3 Degeneration of macula and posterior pole
0.748 0.252 0.000
M31 Other necrotising vasculopathies
0.747 0.253 0.000
M62 Other disorders of muscle
0.746 0.254 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.746 0.254 0.000
R26 Abnormalities of gait and mobility
0.746 0.254 0.000
I34 Nonrheumatic mitral valve disorders
0.745 0.255 0.000
D86 Sarcoidosis
0.745 0.255 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.744 0.256 0.000
S10-S19 Injuries to the neck
0.743 0.257 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.743 0.257 0.000
Y43 Primarily systemic agents
0.741 0.259 0.000
I62 Other nontraumatic intracranial haemorrhage
0.741 0.259 0.000
H55-H59 Other disorders of eye and adnexa
0.740 0.260 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.740 0.260 0.000
C51-C58 Malignant neoplasms of female genital organs
0.740 0.260 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.739 0.261 0.000
H04.1 Other disorders of lachrymal gland
0.739 0.261 0.000
H81 Disorders of vestibular function
0.738 0.262 0.000
K74 Fibrosis and cirrhosis of liver
0.737 0.263 0.000
R94.4 Abnormal results of kidney function studies
0.736 0.264 0.000
H33.5 Other retinal detachments
0.736 0.264 0.000
J18.0 Bronchopneumonia, unspecified
0.736 0.264 0.000
H44 Disorders of globe
0.735 0.265 0.000
R73 Elevated blood glucose level
0.735 0.265 0.000
J92.9 Pleural plaque without asbestos
0.735 0.265 0.000
J14 Pneumonia due to Haemophilus influenzae
0.734 0.266 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.734 0.266 0.000
N13.3 Other and unspecified hydronephrosis
0.732 0.268 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.731 0.269 0.000
M21 Other acquired deformities of limbs
0.730 0.270 0.000
E07 Other disorders of thyroid
0.729 0.271 0.000
J69 Pneumonitis due to solids and liquids
0.727 0.273 0.000
C60-C63 Malignant neoplasms of male genital organs
0.727 0.273 0.000
M00-M03 Infectious arthropathies
0.727 0.273 0.000
S02.4 Fracture of malar and maxillary bones
0.727 0.273 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.726 0.274 0.000
M10 Gout
0.726 0.274 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.725 0.275 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.724 0.276 0.000
H04.2 Epiphora
0.723 0.277 0.000
D70 Agranulocytosis
0.723 0.277 0.000
N42.8 Other specified disorders of prostate
0.721 0.279 0.000
H90.2 Conductive hearing loss, unspecified
0.721 0.279 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.720 0.280 0.000
S42 Fracture of shoulder and upper arm
0.720 0.280 0.000
J98.4 Other disorders of lung
0.719 0.281 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.719 0.281 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.718 0.282 0.000
S32 Fracture of lumbar spine and pelvis
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N37 Urethral disorders in diseases classified elsewhere
0.716 0.283 0.000
N34 Urethritis and urethral syndrome
0.716 0.283 0.000
N33 Bladder disorders in diseases classified elsewhere
0.716 0.283 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
I49.3 Ventricular premature depolarisation
0.716 0.284 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.716 0.284 0.000
N46 Male infertility
0.716 0.284 0.000
N44 Torsion of testis
0.716 0.284 0.000
J17 Pneumonia in diseases classified elsewhere
0.715 0.285 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.715 0.285 0.000
J12 Viral pneumonia, not elsewhere classified
0.715 0.285 0.000
J11 Influenza, virus not identified
0.715 0.285 0.000
J10 Influenza due to identified influenza virus
0.715 0.285 0.000
J09 Influenza due to certain identified influenza virus
0.715 0.285 0.000
I61 Intracerebral haemorrhage
0.715 0.285 0.000
H43 Disorders of vitreous body
0.715 0.285 0.000
M07.3 Other psoriatic arthropathies
0.715 0.285 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.714 0.285 0.000
Chapter XXII Codes for special purposes
0.714 0.286 0.000
I72 Other aneurysm
0.714 0.286 0.000
I73 Other peripheral vascular diseases
0.714 0.286 0.000
J18.8 Other pneumonia, organism unspecified
0.713 0.286 0.000
J18.2 Hypostatic pneumonia, unspecified
0.713 0.286 0.000
H53 Visual disturbances
0.714 0.286 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.713 0.287 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.712 0.288 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.712 0.288 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.711 0.289 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.711 0.289 0.000
W13 Fall from, out of or through building or structure
0.710 0.289 0.000
I71.0 Dissection of aorta [any part]
0.710 0.290 0.000
I44.0 Atrioventricular block, first degree
0.710 0.290 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.710 0.290 0.000
M40-M43 Deforming dorsopathies
0.709 0.291 0.000
N48.4 Impotence of organic origin
0.709 0.291 0.000
M14 Arthropathies in other diseases classified elsewhere
0.709 0.291 0.000
M12 Other specific arthropathies
0.709 0.291 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.709 0.291 0.000
M08 Juvenile arthritis
0.709 0.291 0.000
I95 Hypotension
0.709 0.291 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.709 0.291 0.000
D55-D59 Haemolytic anaemias
0.708 0.291 0.000
Y95 Nosocomial condition
0.708 0.292 0.000
J94 Other pleural conditions
0.708 0.292 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.707 0.293 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.707 0.293 0.000
K70 Alcoholic liver disease
0.707 0.293 0.000
J93 Pneumothorax
0.706 0.294 0.000
N32.4 Rupture of bladder, nontraumatic
0.706 0.294 0.000
N32.2 Vesical fistula, not elsewhere classified
0.706 0.294 0.000
N32.1 Vesicointestinal fistula
0.706 0.294 0.000
M06.8 Other specified rheumatoid arthritis
0.706 0.294 0.000
M06.4 Inflammatory polyarthropathy
0.706 0.294 0.000
M06.3 Rheumatoid nodule
0.706 0.294 0.000
M06.2 Rheumatoid bursitis
0.706 0.294 0.000
M06.1 Adult-onset Still's disease
0.706 0.294 0.000
J43.9 Emphysema, unspecified
0.705 0.295 0.000
T33-T35 Frostbite
0.704 0.295 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.704 0.295 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.704 0.295 0.000
T00-T07 Injuries involving multiple body regions
0.704 0.295 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.703 0.296 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.703 0.296 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.703 0.296 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.703 0.296 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.703 0.296 0.000
R77 Other abnormalities of plasma proteins
0.703 0.296 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.703 0.296 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.703 0.296 0.000
R71 Abnormality of red blood cells
0.703 0.296 0.000
N30.4 Irradiation cystitis
0.703 0.296 0.000
N30.0 Acute cystitis
0.703 0.296 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.703 0.297 0.000
I05-I09 Chronic rheumatic heart diseases
0.702 0.297 0.000
G70-G73 Diseases of myoneural junction and muscle
0.701 0.298 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.701 0.299 0.000
N36.9 Urethral disorder, unspecified
0.701 0.299 0.000
N36.3 Prolapsed urethral mucosa
0.701 0.299 0.000
N36.1 Urethral diverticulum
0.701 0.299 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.700 0.300 0.000
N41 Inflammatory diseases of prostate
0.700 0.300 0.000
H05 Disorders of orbit
0.700 0.300 0.000
V10-V19 Pedal cyclist injured in transport accident
0.700 0.300 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.699 0.301 0.000
M80-M85 Disorders of bone density and structure
0.699 0.301 0.000
G93.6 Cerebral oedema
0.699 0.301 0.000
M25 Other joint disorders, not elsewhere classified
0.698 0.302 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.698 0.302 0.000
E03 Other hypothyroidism
0.698 0.302 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.697 0.303 0.000
M06.0 Seronegative rheumatoid arthritis
0.696 0.303 0.000
S60-S69 Injuries to the wrist and hand
0.696 0.304 0.000
I45 Other conduction disorders
0.696 0.304 0.000
G95 Other diseases of spinal cord
0.695 0.305 0.000
N48.5 Ulcer of penis
0.694 0.306 0.000
N48.3 Priapism
0.694 0.306 0.000
N48.2 Other inflammatory disorders of penis
0.694 0.306 0.000
S06 Intracranial injury
0.694 0.306 0.000
Y35-Y36 Legal intervention and operations of war
0.693 0.307 0.000
Y10-Y34 Event of undetermined intent
0.693 0.307 0.000
Y00-Y09 Assault
0.693 0.307 0.000
X85-X99 Assault
0.693 0.307 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.693 0.307 0.000
X50-X57 Overexertion, travel and privation
0.693 0.307 0.000
X30-X39 Exposure to forces of nature
0.693 0.307 0.000
X20-X29 Contact with venomous animals and plants
0.693 0.307 0.000
X10-X19 Contact with heat and hot substances
0.693 0.307 0.000
X00-X09 Exposure to smoke, fire and flames
0.693 0.307 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.693 0.307 0.000
W75-W84 Other accidental threats to breathing
0.693 0.307 0.000
W65-W74 Accidental drowning and submersion
0.693 0.307 0.000
W50-W64 Exposure to animate mechanical forces
0.693 0.307 0.000
V98-V99 Other and unspecified transport accidents
0.693 0.307 0.000
V95-V97 Air and space transport accidents
0.693 0.307 0.000
V90-V94 Water transport accidents
0.693 0.307 0.000
V70-V79 Bus occupant injured in transport accident
0.693 0.307 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.693 0.307 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.693 0.307 0.000
V40-V49 Car occupant injured in transport accident
0.693 0.307 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.693 0.307 0.000
V01-V09 Pedestrian injured in transport accident
0.693 0.307 0.000
E87.6 Hypokalaemia
0.693 0.307 0.000
K76 Other diseases of liver
0.693 0.307 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.692 0.308 0.000
G96 Other disorders of central nervous system
0.691 0.308 0.000
R79.0 Abnormal level of blood mineral
0.691 0.309 0.000
M34.8 Other forms of systemic sclerosis
0.691 0.309 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.691 0.309 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.691 0.309 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.691 0.309 0.000
M24 Other specific joint derangements
0.690 0.310 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.690 0.310 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.690 0.310 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.690 0.310 0.000
I27.0 Primary pulmonary hypertension
0.690 0.310 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.689 0.311 0.000
H31 Other disorders of choroid
0.689 0.311 0.000
H30 Chorioretinal inflammation
0.689 0.311 0.000
N10 Acute tubulo-interstitial nephritis
0.688 0.312 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.688 0.312 0.000
W19 Unspecified fall
0.688 0.312 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.688 0.312 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.688 0.312 0.000
J15.1 Pneumonia due to Pseudomonas
0.688 0.312 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.687 0.312 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.687 0.312 0.000
S09 Other and unspecified injuries of head
0.687 0.313 0.000
M34.1 CR(E)ST syndrome
0.687 0.313 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.687 0.313 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.686 0.313 0.000
N48.6 Balanitis xerotica obliterans
0.686 0.314 0.000
E40-E46 Malnutrition
0.685 0.315 0.000
H33.3 Retinal breaks without detachment
0.685 0.315 0.000
X60-X84 Intentional self-harm
0.684 0.315 0.000
H80 Otosclerosis
0.684 0.316 0.000
M65-M68 Disorders of synovium and tendon
0.684 0.316 0.000
B37 Candidiasis
0.683 0.317 0.000
J46 Status asthmaticus
0.683 0.317 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.682 0.318 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.681 0.319 0.000
N15 Other renal tubulo-interstitial diseases
0.681 0.319 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.681 0.319 0.000
I67.9 Cerebrovascular disease, unspecified
0.680 0.320 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.680 0.320 0.000
G90 Disorders of autonomic nervous system
0.680 0.320 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.680 0.320 0.000
G92 Toxic encephalopathy
0.680 0.320 0.000
C78.2 Secondary malignant neoplasm of pleura
0.680 0.320 0.000
I46 Cardiac arrest
0.679 0.321 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.679 0.321 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.679 0.321 0.000
R29.4 Clicking hip
0.679 0.321 0.000
R29.3 Abnormal posture
0.679 0.321 0.000
R29.2 Abnormal reflex
0.679 0.321 0.000
R29.1 Meningismus
0.679 0.321 0.000
R29.0 Tetany
0.679 0.321 0.000
V20-V29 Motorcycle rider injured in transport accident
0.678 0.321 0.000
M05 Seropositive rheumatoid arthritis
0.678 0.322 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.677 0.323 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.677 0.323 0.000
C79.6 Secondary malignant neoplasm of ovary
0.677 0.323 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.677 0.323 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.677 0.323 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.677 0.323 0.000
I37 Pulmonary valve disorders
0.677 0.323 0.000
I10-I15 Hypertensive diseases
0.677 0.323 0.000
M34.9 Systemic sclerosis, unspecified
0.676 0.323 0.000
I49.0 Ventricular fibrillation and flutter
0.676 0.324 0.000
R23 Other skin changes
0.675 0.325 0.000
E04.9 Non-toxic goitre, unspecified
0.674 0.326 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.674 0.326 0.000
H53.0 Amblyopia ex anopsia
0.673 0.327 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.673 0.327 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.673 0.327 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.672 0.327 0.000
M33 Dermatopolymyositis
0.672 0.327 0.000
M32 Systemic lupus erythematosus
0.672 0.327 0.000
M30 Polyarteritis nodosa and related conditions
0.672 0.327 0.000
J44 Other chronic obstructive pulmonary disease
0.672 0.328 0.000
M62.8 Other specified disorders of muscle
0.671 0.329 0.000
J15.4 Pneumonia due to other streptococci
0.670 0.330 0.000
H52.1 Myopia
0.669 0.331 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.669 0.331 0.000
R94.3 Abnormal results of cardiovascular function studies
0.668 0.332 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.668 0.332 0.000
H92.0 Otalgia
0.668 0.332 0.000
H04.9 Disorder of lachrymal system, unspecified
0.666 0.334 0.000
H04.8 Other disorders of lachrymal system
0.666 0.334 0.000
H04.6 Other changes in lachrymal passages
0.666 0.334 0.000
H04.4 Chronic inflammation of lachrymal passages
0.666 0.334 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.666 0.334 0.000
H04.0 Dacryoadenitis
0.666 0.334 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.666 0.334 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.666 0.334 0.000
H02.5 Other disorders affecting eyelid function
0.665 0.335 0.000
N43 Hydrocele and spermatocele
0.665 0.335 0.000
M11 Other crystal arthropathies
0.665 0.335 0.000
Q80-Q89 Other congenital malformations
0.665 0.335 0.000
I30 Acute pericarditis
0.664 0.336 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.664 0.336 0.000
M92 Other juvenile osteochondrosis
0.664 0.336 0.000
G20-G26 Extrapyramidal and movement disorders
0.663 0.337 0.000
W08 Fall involving other furniture
0.663 0.337 0.000
I27.9 Pulmonary heart disease, unspecified
0.663 0.337 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.661 0.339 0.000
J20-J22 Other acute lower respiratory infections
0.661 0.339 0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae
0.660 0.340 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.660 0.340 0.000
N13.8 Other obstructive and reflux uropathy
0.660 0.340 0.000
N32.3 Diverticulum of bladder
0.659 0.340 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.659 0.340 0.000
E00 Congenital iodine-deficiency syndrome
0.659 0.340 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.659 0.340 0.000
N99-N99 Other disorders of the genitourinary system
0.659 0.341 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.659 0.341 0.000
I70 Atherosclerosis
0.658 0.342 0.000
K72 Hepatic failure, not elsewhere classified
0.658 0.342 0.000
M35.7 Hypermobility syndrome
0.658 0.342 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.657 0.343 0.000
J69.0 Pneumonitis due to food and vomit
0.657 0.343 0.000
H81.0 Meniere's disease
0.656 0.344 0.000
H65 Nonsuppurative otitis media
0.656 0.344 0.000
M54 Dorsalgia
0.655 0.345 0.000
C79.2 Secondary malignant neoplasm of skin
0.655 0.345 0.000
Y52 Agents primarily affecting the cardiovascular system
0.655 0.345 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.655 0.345 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.654 0.346 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.654 0.346 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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