TreeWAS – Variant ID: rs77436432

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter X Diseases of the respiratory system	1.000	0.000
# Top node	1.000	0.000
I10 Essential (primary) hypertension	1.000	0.000
J40-J47 Chronic lower respiratory diseases	1.000	0.000
I10-I15 Hypertensive diseases	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
J44 Other chronic obstructive pulmonary disease	0.998	0.002
J44.9 Chronic obstructive pulmonary disease, unspecified	0.996	0.004
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.993	0.007
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.992	0.008
R03 Abnormal blood-pressure reading, without diagnosis	0.989	0.011
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.989	0.011
R06 Abnormalities of breathing	0.979	0.021
Chapter VI Diseases of the nervous system	0.978	0.022
R06.0 Dyspnoea	0.977	0.023
Chapter XX External causes of morbidity and mortality	0.972	0.028
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.971	0.029
J00-J06 Acute upper respiratory infections	0.967	0.033
Chapter IV Endocrine, nutritional and metabolic diseases	0.966	0.034
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.963	0.037
E78.0 Pure hypercholesterolaemia	0.962	0.038
E70-E90 Metabolic disorders	0.962	0.038
J30-J39 Other diseases of upper respiratory tract	0.955	0.045
Chapter I Certain infectious and parasitic diseases	0.949	0.051
J02 Acute pharyngitis	0.945	0.055
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.939	0.061
J47 Bronchiectasis	0.937	0.063
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.929	0.071
J02.9 Acute pharyngitis, unspecified	0.929	0.071
J09-J18 Influenza and pneumonia	0.928	0.072
J45 Asthma	0.916	0.084
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.912	0.088
I80 Phlebitis and thrombophlebitis	0.905	0.095
G30-G32 Other degenerative diseases of the nervous system	0.901	0.099
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.898	0.102
Chapter VIII Diseases of the ear and mastoid process	0.897	0.103
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.886	0.114
J45.9 Asthma, unspecified	0.885	0.115
R23 Other skin changes	0.878	0.122
I12 Hypertensive renal disease	0.878	0.122
S90-S99 Injuries to the ankle and foot	0.862	0.138
J34 Other disorders of nose and nasal sinuses	0.859	0.141
B95-B98 Bacterial, viral and other infectious agents	0.858	0.142
I05-I09 Chronic rheumatic heart diseases	0.857	0.143
R20 Disturbances of skin sensation	0.853	0.147
J46 Status asthmaticus	0.852	0.148
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.847	0.153
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.843	0.157
I70-I79 Diseases of arteries, arterioles and capillaries	0.837	0.163
G90-G99 Other disorders of the nervous system	0.835	0.165
R05 Cough	0.835	0.165
E78.2 Mixed hyperlipidaemia	0.833	0.167
Chapter XV Pregnancy, childbirth and the puerperium	0.833	0.167
G80-G83 Cerebral palsy and other paralytic syndromes	0.829	0.171
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.827	0.173
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.818	0.182
H60-H62 Diseases of external ear	0.816	0.184
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.816	0.184
R01 Cardiac murmurs and other cardiac sounds	0.815	0.185
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.814	0.186
E78.5 Hyperlipidaemia, unspecified	0.814	0.186
E88 Other metabolic disorders	0.808	0.192
G50-G59 Nerve, nerve root and plexus disorders	0.808	0.192
R06.2 Wheezing	0.807	0.193
G70-G73 Diseases of myoneural junction and muscle	0.803	0.197
R20.2 Paraesthesia of skin	0.800	0.200
G30 Alzheimer's disease	0.800	0.200
I12.0 Hypertensive renal disease with renal failure	0.796	0.204
I71 Aortic aneurysm and dissection	0.796	0.204
I08 Multiple valve diseases	0.793	0.207
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.793	0.207
T79-T79 Certain early complications of trauma	0.791	0.209
R23.2 Flushing	0.789	0.211
A50-A64 Infections with a predominantly sexual mode of transmission	0.788	0.212
R06.6 Hiccough	0.787	0.213
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.784	0.216
B20-B24 Human immunodeficiency virus [HIV] disease	0.784	0.216
J32 Chronic sinusitis	0.782	0.218
W50-W64 Exposure to animate mechanical forces	0.782	0.218
I80.8 Phlebitis and thrombophlebitis of other sites	0.781	0.219
B35-B49 Mycoses	0.779	0.221
Y53 Agents primarily affecting the gastro-intestinal system	0.779	0.221
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.778	0.222
J95-J99 Other diseases of the respiratory system	0.777	0.223
Y46 Antiepileptics and anti-Parkinsonism drugs	0.774	0.226
Y52 Agents primarily affecting the cardiovascular system	0.772	0.228
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.771	0.229
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.767	0.233
J00 Acute nasopharyngitis [common cold]	0.766	0.234
T81 Complications of procedures, not elsewhere classified	0.765	0.235
S00-S09 Injuries to the head	0.765	0.235
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.764	0.236
Chapter VII Diseases of the eye and adnexa	0.764	0.236
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.763	0.237
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.762	0.238
J40 Bronchitis, not specified as acute or chronic	0.760	0.240
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.760	0.240
X60-X84 Intentional self-harm	0.759	0.241
I82 Other venous embolism and thrombosis	0.759	0.241
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.758	0.242
R23.8 Other and unspecified skin changes	0.758	0.242
J34.2 Deviated nasal septum	0.757	0.243
J39 Other diseases of upper respiratory tract	0.755	0.245
S50-S59 Injuries to the elbow and forearm	0.754	0.246
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.753	0.247
B25-B34 Other viral diseases	0.753	0.247
G90 Disorders of autonomic nervous system	0.752	0.248
J18 Pneumonia, organism unspecified	0.752	0.248
J37 Chronic laryngitis and laryngotracheitis	0.751	0.249
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.748	0.252
O16 Unspecified maternal hypertension	0.748	0.252
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.747	0.253
Y49 Psychotropic drugs, not elsewhere classified	0.746	0.254
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.745	0.255
T93 Sequelae of injuries of lower limb	0.744	0.256
T85 Complications of other internal prosthetic devices, implants and grafts	0.742	0.258
J15 Bacterial pneumonia, not elsewhere classified	0.739	0.261
V20-V29 Motorcycle rider injured in transport accident	0.739	0.261
S91 Open wound of ankle and foot	0.737	0.263
J42 Unspecified chronic bronchitis	0.736	0.263
S20-S29 Injuries to the thorax	0.735	0.265
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.735	0.265
E78.4 Other hyperlipidaemia	0.735	0.265
E50-E64 Other nutritional deficiencies	0.733	0.267
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.733	0.267
T15-T19 Effects of foreign body entering through natural orifice	0.731	0.269
E86 Volume depletion	0.730	0.270
I08.0 Disorders of both mitral and aortic valves	0.730	0.270
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.729	0.271
J13 Pneumonia due to Streptococcus pneumoniae	0.728	0.272
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.728	0.272
J34.8 Other specified disorders of nose and nasal sinuses	0.727	0.273
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.725	0.275
Y51 Drugs primarily affecting the autonomic nervous system	0.724	0.276
J44.8 Other specified chronic obstructive pulmonary disease	0.723	0.276
G00-G09 Inflammatory diseases of the central nervous system	0.723	0.277
S01 Open wound of head	0.723	0.277
G55.2 Nerve root and plexus compressions in spondylosis	0.723	0.277
E78.1 Pure hyperglyceridaemia	0.723	0.277
J04 Acute laryngitis and tracheitis	0.722	0.278
R06.1 Stridor	0.720	0.279
J17 Pneumonia in diseases classified elsewhere	0.719	0.281
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.719	0.281
Y57 Other and unspecified drugs and medicaments	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
J41 Simple and mucopurulent chronic bronchitis	0.717	0.283
I15 Secondary hypertension	0.717	0.283
I13 Hypertensive heart and renal disease	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
S60-S69 Injuries to the wrist and hand	0.717	0.283
V80-V89 Other land transport accidents	0.716	0.284
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.715	0.285
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.715	0.285
I87 Other disorders of veins	0.715	0.285
W00-W19 Falls	0.715	0.285
Y00-Y09 Assault	0.714	0.285
J31.0 Chronic rhinitis	0.714	0.286
H80-H83 Diseases of inner ear	0.714	0.286
Y43 Primarily systemic agents	0.713	0.287
R95-R99 Ill-defined and unknown causes of mortality	0.712	0.288
V40-V49 Car occupant injured in transport accident	0.711	0.289
J11 Influenza, virus not identified	0.710	0.290
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.710	0.290
H60 Otitis externa	0.709	0.291
T66-T78 Other and unspecified effects of external causes	0.707	0.293
G99 Other disorders of nervous system in diseases classified elsewhere	0.704	0.296
R06.7 Sneezing	0.702	0.298
R06.3 Periodic breathing	0.702	0.298
S10-S19 Injuries to the neck	0.702	0.298
V10-V19 Pedal cyclist injured in transport accident	0.701	0.298
S40-S49 Injuries to the shoulder and upper arm	0.701	0.299
B15-B19 Viral hepatitis	0.701	0.299
J10 Influenza due to identified influenza virus	0.700	0.300
B99-B99 Other infectious diseases	0.699	0.301
G82 Paraplegia and tetraplegia	0.698	0.302
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.697	0.303
B65-B83 Helminthiases	0.697	0.303
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.697	0.303
Y35-Y36 Legal intervention and operations of war	0.697	0.303
Y10-Y34 Event of undetermined intent	0.697	0.303
X85-X99 Assault	0.697	0.303
X58-X59 Accidental exposure to other and unspecified factors	0.697	0.303
X30-X39 Exposure to forces of nature	0.697	0.303
X20-X29 Contact with venomous animals and plants	0.697	0.303
X10-X19 Contact with heat and hot substances	0.697	0.303
X00-X09 Exposure to smoke, fire and flames	0.697	0.303
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.697	0.303
W75-W84 Other accidental threats to breathing	0.697	0.303
W65-W74 Accidental drowning and submersion	0.697	0.303
V98-V99 Other and unspecified transport accidents	0.697	0.303
V95-V97 Air and space transport accidents	0.697	0.303
V90-V94 Water transport accidents	0.697	0.303
V70-V79 Bus occupant injured in transport accident	0.697	0.303
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.697	0.303
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.697	0.303
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.697	0.303
V01-V09 Pedestrian injured in transport accident	0.697	0.303
S70-S79 Injuries to the hip and thigh	0.696	0.304
T33-T35 Frostbite	0.696	0.304
T26-T28 Burns and corrosions confined to eye and internal organs	0.696	0.304
T20-T25 Burns and corrosions of external body surface, specified by site	0.696	0.304
T00-T07 Injuries involving multiple body regions	0.696	0.304
X40-X49 Accidental poisoning by and exposure to noxious substances	0.696	0.304
J03 Acute tonsillitis	0.695	0.305
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.693	0.307
E78.8 Other disorders of lipoprotein metabolism	0.691	0.309
E78.6 Lipoprotein deficiency	0.691	0.309
E78.3 Hyperchylomicronaemia	0.691	0.309
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.690	0.310
J35 Chronic diseases of tonsils and adenoids	0.690	0.310
H61 Other disorders of external ear	0.690	0.310
I60-I69 Cerebrovascular diseases	0.690	0.310
E85 Amyloidosis	0.690	0.310
E84 Cystic fibrosis	0.690	0.310
E79 Disorders of purine and pyrimidine metabolism	0.690	0.310
E77 Disorders of glycoprotein metabolism	0.690	0.310
E76 Disorders of glycosaminoglycan metabolism	0.690	0.310
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.690	0.310
E74 Other disorders of carbohydrate metabolism	0.690	0.310
E73 Lactose intolerance	0.690	0.310
E72 Other disorders of amino-acid metabolism	0.690	0.310
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.690	0.310
E70 Disorders of aromatic amino-acid metabolism	0.690	0.310
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.690	0.310
R23.3 Spontaneous ecchymoses	0.689	0.311
G62 Other polyneuropathies	0.688	0.312
X50-X57 Overexertion, travel and privation	0.686	0.314
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.686	0.314
O00-O08 Pregnancy with abortive outcome	0.685	0.315
E80 Disorders of porphyrin and bilirubin metabolism	0.685	0.315
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.685	0.315
H43-H45 Disorders of vitreous body and globe	0.685	0.315
J32.2 Chronic ethmoidal sinusitis	0.684	0.316
R00 Abnormalities of heart beat	0.683	0.317
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.683	0.317
J01 Acute sinusitis	0.682	0.317
G30.9 Alzheimer's disease, unspecified	0.682	0.318
B85-B89 Pediculosis, acariasis and other infestations	0.680	0.320
B50-B64 Protozoal diseases	0.680	0.320
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.680	0.320
A75-A79 Rickettsioses	0.680	0.320
A70-A74 Other diseases caused by chlamydiae	0.680	0.320
A65-A69 Other spirochaetal diseases	0.680	0.320
A20-A28 Certain zoonotic bacterial diseases	0.680	0.320
A15-A19 Tuberculosis	0.680	0.320
I78 Diseases of capillaries	0.679	0.321
J02.8 Acute pharyngitis due to other specified organisms	0.677	0.322
J02.0 Streptococcal pharyngitis	0.677	0.322
J14 Pneumonia due to Haemophilus influenzae	0.677	0.323
R01.1 Cardiac murmur, unspecified	0.676	0.324
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.675	0.325
A30-A49 Other bacterial diseases	0.673	0.326
Y59 Other and unspecified vaccines and biological substances	0.673	0.327
Y58 Bacterial vaccines	0.673	0.327
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.673	0.327
Y50 Central nervous system stimulants, not elsewhere classified	0.673	0.327
Y48 Anaesthetics and therapeutic gases	0.673	0.327
Y47 Sedatives, hypnotics and antianxiety drugs	0.673	0.327
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.672	0.327
R80 Isolated proteinuria	0.672	0.328
J38.0 Paralysis of vocal cords and larynx	0.671	0.329
Y60-Y69 Misadventures to patients during surgical and medical care	0.671	0.329
J18.1 Lobar pneumonia, unspecified	0.670	0.330
R91 Abnormal findings on diagnostic imaging of lung	0.670	0.330
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.669	0.331
B24 Unspecified human immunodeficiency virus [HIV] disease	0.666	0.334
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.665	0.335
J12 Viral pneumonia, not elsewhere classified	0.665	0.335
J09 Influenza due to certain identified influenza virus	0.665	0.335
B97 Viral agents as the cause of diseases classified to other chapters	0.664	0.335
Y53.1 Other antacids and anti-gastric-secretion drugs	0.664	0.336
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.664	0.336
J34.3 Hypertrophy of nasal turbinates	0.663	0.337
T79 Certain early complications of trauma, not elsewhere classified	0.662	0.338
T90 Sequelae of injuries of head	0.662	0.338
G30.0 Alzheimer's disease with early onset	0.661	0.339
S01.1 Open wound of eyelid and periocular area	0.661	0.339
G90.2 Horner's syndrome	0.660	0.340
Y41 Other systemic anti-infectives and antiparasitics	0.660	0.340
Y40 Systemic antibiotics	0.659	0.341
R27 Other lack of coordination	0.659	0.341
R06.4 Hyperventilation	0.659	0.341
J32.9 Chronic sinusitis, unspecified	0.658	0.342
R81 Glycosuria	0.658	0.342
R77 Other abnormalities of plasma proteins	0.658	0.342
J45.8 Mixed asthma	0.657	0.343
J45.1 Nonallergic asthma	0.657	0.343
Y46.4 Iminostilbenes	0.657	0.343
E65-E68 Obesity and other hyperalimentation	0.656	0.344
G56 Mononeuropathies of upper limb	0.654	0.346
I88 Nonspecific lymphadenitis	0.654	0.346
J30 Vasomotor and allergic rhinitis	0.653	0.347
R07 Pain in throat and chest	0.652	0.348
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.652	0.348
T87 Complications peculiar to reattachment and amputation	0.650	0.350
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.650	0.350
Y95 Nosocomial condition	0.650	0.350
T91 Sequelae of injuries of neck and trunk	0.647	0.353
S01.2 Open wound of nose	0.647	0.353
S91.3 Open wound of other parts of foot	0.647	0.353
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.646	0.354
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.645	0.355
B90-B94 Sequelae of infectious and parasitic diseases	0.643	0.357
H10-H13 Disorders of conjunctiva	0.643	0.357
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.641	0.359
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.641	0.359
G70 Myasthenia gravis and other myoneural disorders	0.641	0.359
S01.5 Open wound of lip and oral cavity	0.641	0.359
J80-J84 Other respiratory diseases principally affecting the interstitium	0.640	0.360
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.640	0.360
G61 Inflammatory polyneuropathy	0.638	0.362
J18.0 Bronchopneumonia, unspecified	0.637	0.363
H50 Other strabismus	0.636	0.364
I67 Other cerebrovascular diseases	0.634	0.366
H61.2 Impacted cerumen	0.634	0.366
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.633	0.367
I82.8 Embolism and thrombosis of other specified veins	0.633	0.367
T98 Sequelae of other and unspecified effects of external causes	0.632	0.368
J38.4 Oedema of larynx	0.632	0.368
I11 Hypertensive heart disease	0.631	0.368
R47-R49 Symptoms and signs involving speech and voice	0.631	0.369
T86 Failure and rejection of transplanted organs and tissues	0.631	0.369
R23.0 Cyanosis	0.630	0.370
B35 Dermatophytosis	0.628	0.372
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.628	0.372
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.627	0.373
G72 Other myopathies	0.627	0.373
S93.1 Dislocation of toe(s)	0.626	0.373
T94 Sequelae of injuries involving multiple and unspecified body regions	0.626	0.374
R23.4 Changes in skin texture	0.625	0.375
G81 Hemiplegia	0.625	0.375
S32 Fracture of lumbar spine and pelvis	0.624	0.376
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.623	0.377
J95 Postprocedural respiratory disorders, not elsewhere classified	0.622	0.378
Y54.5 Other diuretics	0.621	0.379
I87.8 Other specified disorders of veins	0.621	0.379
B34 Viral infection of unspecified site	0.620	0.380
G31.2 Degeneration of nervous system due to alcohol	0.620	0.380
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.620	0.380
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.620	0.380
E16 Other disorders of pancreatic internal secretion	0.620	0.380
R00.2 Palpitations	0.619	0.381
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.618	0.382
S98 Traumatic amputation of ankle and foot	0.618	0.382
S97 Crushing injury of ankle and foot	0.618	0.382
S96 Injury of muscle and tendon at ankle and foot level	0.618	0.382
S95 Injury of blood vessels at ankle and foot level	0.618	0.382
S94 Injury of nerves at ankle and foot level	0.618	0.382
H65-H75 Diseases of middle ear and mastoid	0.617	0.383
R07.0 Pain in throat	0.617	0.383
A80-A89 Viral infections of the central nervous system	0.616	0.384
S92 Fracture of foot, except ankle	0.616	0.384
T88 Other complications of surgical and medical care, not elsewhere classified	0.615	0.385
I09 Other rheumatic heart diseases	0.614	0.385
I06 Rheumatic aortic valve diseases	0.614	0.385
W20-W49 Exposure to inanimate mechanical forces	0.613	0.387
I12.9 Hypertensive renal disease without renal failure	0.613	0.387
I67.9 Cerebrovascular disease, unspecified	0.613	0.387
R20.3 Hyperaesthesia	0.612	0.388
R20.1 Hypoaesthesia of skin	0.612	0.388
R20.0 Anaesthesia of skin	0.612	0.388
S56 Injury of muscle and tendon at forearm level	0.611	0.389
I89.0 Lymphoedema, not elsewhere classified	0.611	0.389
G40-G47 Episodic and paroxysmal disorders	0.611	0.389
O03 Spontaneous abortion	0.610	0.390
G83 Other paralytic syndromes	0.609	0.391
R90 Abnormal findings on diagnostic imaging of central nervous system	0.609	0.391
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.609	0.391
O85-O92 Complications predominantly related to the puerperium	0.609	0.391
S99 Other and unspecified injuries of ankle and foot	0.608	0.392
G54 Nerve root and plexus disorders	0.608	0.392
Y49.2 Other and unspecified antidepressants	0.608	0.392
T95 Sequelae of burns, corrosions and frostbite	0.607	0.392
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.607	0.392
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.607	0.392
I70 Atherosclerosis	0.607	0.393
G60 Hereditary and idiopathic neuropathy	0.607	0.393
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.607	0.393
S01.4 Open wound of cheek and temporomandibular area	0.607	0.393
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.606	0.393
R23.1 Pallor	0.606	0.394
J37.0 Chronic laryngitis	0.606	0.394
S90 Superficial injury of ankle and foot	0.605	0.394
E40-E46 Malnutrition	0.605	0.395
R20.8 Other and unspecified disturbances of skin sensation	0.605	0.395
H60.1 Cellulitis of external ear	0.605	0.395
H90-H95 Other disorders of ear	0.605	0.395
G51 Facial nerve disorders	0.605	0.395
G96 Other disorders of central nervous system	0.604	0.396
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.604	0.396
Y44 Agents primarily affecting blood constituents	0.604	0.396
R01.0 Benign and innocent cardiac murmurs	0.603	0.397
J38.5 Laryngeal spasm	0.603	0.397
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.602	0.398
E20-E35 Disorders of other endocrine glands	0.600	0.399
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.600	0.400
Y52.3 Coronary vasodilators, not elsewhere classified	0.600	0.400
Chapter XXII Codes for special purposes	0.600	0.400
J38.2 Nodules of vocal cords	0.600	0.400
G94 Other disorders of brain in diseases classified elsewhere	0.599	0.401
G98 Other disorders of nervous system, not elsewhere classified	0.599	0.401
G92 Toxic encephalopathy	0.599	0.401
T13 Other injuries of lower limb, level unspecified	0.598	0.402
R27.0 Ataxia, unspecified	0.598	0.402
G31.9 Degenerative disease of nervous system, unspecified	0.598	0.402
Y42.5 Other oestrogens and progestogens	0.598	0.402
S01.9 Open wound of head, part unspecified	0.598	0.402
R77.8 Other specified abnormalities of plasma proteins	0.598	0.402
B37 Candidiasis	0.597	0.403
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.596	0.404
J60-J70 Lung diseases due to external agents	0.595	0.405
G80 Infantile cerebral palsy	0.594	0.405
G55.0 Nerve root and plexus compressions in neoplastic disease	0.593	0.407
H44 Disorders of globe	0.593	0.407
S22 Fracture of rib(s), sternum and thoracic spine	0.593	0.407
G62.9 Polyneuropathy, unspecified	0.591	0.409
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.591	0.409
S27 Injury of other and unspecified intrathoracic organs	0.591	0.409
A63.0 Anogenital (venereal) warts	0.590	0.410
Q50-Q56 Congenital malformations of genital organs	0.589	0.411
J39.2 Other diseases of pharynx	0.589	0.411
S62 Fracture at wrist and hand level	0.589	0.411
I08.1 Disorders of both mitral and tricuspid valves	0.587	0.412
H25-H28 Disorders of lens	0.588	0.412
J36 Peritonsillar abscess	0.587	0.413
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.587	0.413
O15 Eclampsia	0.587	0.413
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.587	0.413
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.586	0.414
W13 Fall from, out of or through building or structure	0.586	0.414
G91 Hydrocephalus	0.586	0.414
H80 Otosclerosis	0.585	0.415
I71.0 Dissection of aorta [any part]	0.585	0.415
H62 Disorders of external ear in diseases classified elsewhere	0.585	0.415
G64 Other disorders of peripheral nervous system	0.585	0.415
R01.2 Other cardiac sounds	0.584	0.416
T11 Other injuries of upper limb, level unspecified	0.584	0.416
J31.2 Chronic pharyngitis	0.584	0.416
J31.1 Chronic nasopharyngitis	0.584	0.416
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.582	0.418
E61 Deficiency of other nutrient elements	0.581	0.419
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.581	0.419
R82 Other abnormal findings in urine	0.581	0.419
I72 Other aneurysm	0.581	0.419
G90.0 Idiopathic peripheral autonomic neuropathy	0.580	0.420
G90.9 Disorder of autonomic nervous system, unspecified	0.580	0.420
H11 Other disorders of conjunctiva	0.580	0.420
W50 Hit, struck, kicked, twisted, bitten or scratched by another person	0.579	0.421
E88.9 Metabolic disorder, unspecified	0.579	0.421
E88.8 Other specified metabolic disorders	0.579	0.421
E88.3 Tumour lysis syndrome	0.579	0.421
E88.2 Lipomatosis, not elsewhere classified	0.579	0.421
E88.1 Lipodystrophy, not elsewhere classified	0.579	0.421
G53 Cranial nerve disorders in diseases classified elsewhere	0.579	0.421
G52 Disorders of other cranial nerves	0.579	0.421
J99 Respiratory disorders in diseases classified elsewhere	0.577	0.422
G35-G37 Demyelinating diseases of the central nervous system	0.577	0.423
S51 Open wound of forearm	0.576	0.424
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.576	0.424
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.576	0.424
G71 Primary disorders of muscles	0.576	0.424
J15.1 Pneumonia due to Pseudomonas	0.576	0.424
H60.3 Other infective otitis externa	0.575	0.425
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.575	0.425
J35.0 Chronic tonsillitis	0.575	0.425
I86 Varicose veins of other sites	0.574	0.426
G30.8 Other Alzheimer's disease	0.573	0.426
G30.1 Alzheimer's disease with late onset	0.573	0.426
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.573	0.427
O12.1 Gestational proteinuria	0.573	0.427
I82.9 Embolism and thrombosis of unspecified vein	0.573	0.427
S64 Injury of nerves at wrist and hand level	0.572	0.428
I08.2 Disorders of both aortic and tricuspid valves	0.572	0.428
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.572	0.428
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.571	0.428
T93.1 Sequelae of fracture of femur	0.571	0.428
T93.8 Sequelae of other specified injuries of lower limb	0.571	0.429
I71.8 Aortic aneurysm of unspecified site, ruptured	0.571	0.429
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.571	0.429
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.571	0.429
I71.3 Abdominal aortic aneurysm, ruptured	0.571	0.429
I71.1 Thoracic aortic aneurysm, ruptured	0.571	0.429
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.570	0.430
G82.2 Paraplegia, unspecified	0.570	0.430
I05 Rheumatic mitral valve diseases	0.570	0.430
J17.2 Pneumonia in mycoses	0.570	0.430
J39.8 Other specified diseases of upper respiratory tract	0.570	0.430
G50 Disorders of trigeminal nerve	0.570	0.430
T79.7 Traumatic subcutaneous emphysema	0.570	0.430
S69 Other and unspecified injuries of wrist and hand	0.569	0.431
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.569	0.431
I08.9 Multiple valve disease, unspecified	0.569	0.431
J38.6 Stenosis of larynx	0.569	0.431
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters	0.569	0.431
T93.9 Sequelae of unspecified injury of lower limb	0.568	0.432
T81.7 Vascular complications following a procedure, not elsewhere classified	0.568	0.432
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.567	0.433
J15.2 Pneumonia due to staphylococcus	0.567	0.433
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.566	0.434
H43 Disorders of vitreous body	0.566	0.434

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations