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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77499291
log Bayes Factor = 13.2457
Chromosome 10   position 121,191,404  (GRCh37) Explore rs77499291 on Ensembl!
Variant rs77499291 is part of Cluster X0032

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
M45-M49 Spondylopathies
0.999 0.001 0.000
M47 Spondylosis
0.998 0.002 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.997 0.003 0.000
M50-M54 Other dorsopathies
0.997 0.003 0.000
C79 Secondary malignant neoplasm of other sites
0.996 0.004 0.000
Chapter V Mental and behavioural disorders
0.995 0.005 0.000
M47.8 Other spondylosis
0.994 0.006 0.000
I30-I52 Other forms of heart disease
0.992 0.008 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.992 0.008 0.000
I25 Chronic ischaemic heart disease
0.991 0.009 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.990 0.010 0.000
I21 Acute myocardial infarction
0.985 0.015 0.000
M54 Dorsalgia
0.984 0.016 0.000
M47.82 Other spondylosis (Cervical region)
0.982 0.018 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.981 0.019 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.979 0.021 0.000
N17-N19 Renal failure
0.975 0.025 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.975 0.025 0.000
Chapter XIV Diseases of the genitourinary system
0.974 0.026 0.000
N18 Chronic renal failure
0.974 0.026 0.000
M51 Other intervertebral disk disorders
0.961 0.039 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.959 0.041 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.956 0.044 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.956 0.044 0.000
N18.9 Chronic renal failure, unspecified
0.955 0.045 0.000
I35 Nonrheumatic aortic valve disorders
0.954 0.046 0.000
M15-M19 Arthrosis
0.954 0.046 0.000
M54.5 Low back pain
0.954 0.046 0.000
N18.3 Chronic kidney disease, stage 3
0.949 0.051 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.944 0.056 0.000
F10.1 Harmful use
0.938 0.062 0.000
M51.2 Other specified intervertebral disk displacement
0.937 0.063 0.000
I74 Arterial embolism and thrombosis
0.929 0.071 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.928 0.072 0.000
C64-C68 Malignant neoplasms of urinary tract
0.925 0.075 0.000
I44 Atrioventricular and left bundle-branch block
0.921 0.079 0.000
I42 Cardiomyopathy
0.920 0.080 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.918 0.082 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.916 0.084 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.913 0.087 0.000
M47.9 Spondylosis, unspecified
0.904 0.096 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.902 0.098 0.000
D68 Other coagulation defects
0.899 0.101 0.000
M54.59 Low back pain (Site unspecified)
0.897 0.103 0.000
I35.0 Aortic (valve) stenosis
0.893 0.107 0.000
I71 Aortic aneurysm and dissection
0.893 0.107 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.890 0.110 0.000
D69 Purpura and other haemorrhagic conditions
0.889 0.111 0.000
M19 Other arthrosis
0.888 0.112 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.887 0.113 0.000
M80-M85 Disorders of bone density and structure
0.880 0.120 0.000
F10.0 Acute intoxication
0.879 0.121 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.876 0.124 0.000
D10-D36 Benign neoplasms
0.875 0.125 0.000
F17.1 Harmful use
0.875 0.125 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.875 0.125 0.000
M40-M43 Deforming dorsopathies
0.870 0.129 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.868 0.132 0.000
I25.1 Atherosclerotic heart disease
0.868 0.132 0.000
F10.3 Withdrawal state
0.866 0.134 0.000
I47 Paroxysmal tachycardia
0.860 0.140 0.000
M18 Arthrosis of first carpometacarpal joint
0.858 0.142 0.000
N19 Unspecified renal failure
0.858 0.142 0.000
C34 Malignant neoplasm of bronchus and lung
0.856 0.144 0.000
M54.2 Cervicalgia
0.853 0.147 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.847 0.153 0.000
M47.86 Other spondylosis (Lumbar region)
0.847 0.153 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.846 0.154 0.000
M47.2 Other spondylosis with radiculopathy
0.842 0.157 0.000
M54.57 Low back pain (Lumbosacral region)
0.842 0.158 0.000
L60-L75 Disorders of skin appendages
0.841 0.159 0.000
N00-N08 Glomerular diseases
0.841 0.159 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.837 0.163 0.000
I42.9 Cardiomyopathy, unspecified
0.834 0.166 0.000
M46 Other inflammatory spondylopathies
0.833 0.167 0.000
M86-M90 Other osteopathies
0.831 0.168 0.000
M16 Coxarthrosis [arthrosis of hip]
0.827 0.173 0.000
I77 Other disorders of arteries and arterioles
0.824 0.176 0.000
I44.7 Left bundle-branch block, unspecified
0.822 0.178 0.000
N17 Acute renal failure
0.818 0.182 0.000
C67 Malignant neoplasm of bladder
0.817 0.183 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.817 0.183 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.815 0.185 0.000
I24 Other acute ischaemic heart diseases
0.814 0.186 0.000
M48 Other spondylopathies
0.812 0.188 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.812 0.188 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.810 0.190 0.000
D68.2 Hereditary deficiency of other clotting factors
0.810 0.190 0.000
Chapter XI Diseases of the digestive system
0.808 0.192 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.805 0.195 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.802 0.197 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.802 0.198 0.000
M54.6 Pain in thoracic spine
0.801 0.199 0.000
C34.9 Bronchus or lung, unspecified
0.800 0.200 0.000
N10-N16 Renal tubulo-interstitial diseases
0.797 0.203 0.000
M41 Scoliosis
0.796 0.204 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.795 0.205 0.000
C51-C58 Malignant neoplasms of female genital organs
0.792 0.208 0.000
M19.9 Arthrosis, unspecified
0.792 0.208 0.000
I35.1 Aortic (valve) insufficiency
0.792 0.208 0.000
Chapter XXII Codes for special purposes
0.792 0.208 0.000
I45 Other conduction disorders
0.790 0.210 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.790 0.210 0.000
D22 Melanocytic naevi
0.790 0.210 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.789 0.211 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.787 0.213 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.785 0.215 0.000
D75 Other diseases of blood and blood-forming organs
0.781 0.219 0.000
K86 Other diseases of pancreas
0.781 0.219 0.000
L72.1 Trichilemmal cyst
0.781 0.219 0.000
M16.1 Other primary coxarthrosis
0.780 0.220 0.000
M84 Disorders of continuity of bone
0.780 0.220 0.000
D68.5 Primary Thrombophilia
0.777 0.223 0.000
C79.2 Secondary malignant neoplasm of skin
0.776 0.223 0.000
L20-L30 Dermatitis and eczema
0.776 0.224 0.000
M54.9 Dorsalgia, unspecified
0.775 0.225 0.000
M19.94 Arthrosis, unspecified (Hand)
0.775 0.225 0.000
I25.5 Ischaemic cardiomyopathy
0.772 0.228 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.771 0.229 0.000
I22 Subsequent myocardial infarction
0.770 0.230 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.768 0.232 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.767 0.233 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.766 0.234 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.765 0.235 0.000
K85 Acute pancreatitis
0.764 0.236 0.000
M19.0 Primary arthrosis of other joints
0.764 0.236 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.764 0.236 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.764 0.236 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.763 0.237 0.000
N99-N99 Other disorders of the genitourinary system
0.763 0.237 0.000
I42.0 Dilated cardiomyopathy
0.761 0.239 0.000
L03 Cellulitis
0.760 0.240 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.759 0.241 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.757 0.243 0.000
I35.8 Other aortic valve disorders
0.756 0.244 0.000
D45 Polycythaemia vera
0.755 0.245 0.000
D70 Agranulocytosis
0.754 0.246 0.000
S70-S79 Injuries to the hip and thigh
0.753 0.247 0.000
I74.5 Embolism and thrombosis of iliac artery
0.753 0.247 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.751 0.249 0.000
Chapter VIII Diseases of the ear and mastoid process
0.751 0.249 0.000
F10.4 Withdrawal state with delirium
0.749 0.251 0.000
K82 Other diseases of gallbladder
0.748 0.252 0.000
D17 Benign lipomatous neoplasm
0.748 0.252 0.000
M54.29 Cervicalgia-Site unspe
0.747 0.253 0.000
I30 Acute pericarditis
0.747 0.253 0.000
I26 Pulmonary embolism
0.746 0.254 0.000
M41.9 Scoliosis, unspecified
0.743 0.257 0.000
I44.2 Atrioventricular block, complete
0.742 0.257 0.000
M54.50 Low back pain (Multiple sites in spine)
0.741 0.258 0.000
S80-S89 Injuries to the knee and lower leg
0.740 0.260 0.000
M54.4 Lumbago with sciatica
0.739 0.261 0.000
I51 Complications and ill-defined descriptions of heart disease
0.738 0.262 0.000
N18.4 Chronic kidney disease, stage 4
0.737 0.263 0.000
C67.9 Bladder, unspecified
0.735 0.265 0.000
N18.0 End-stage renal disease
0.734 0.266 0.000
D26 Other benign neoplasms of uterus
0.732 0.268 0.000
N03 Chronic nephritic syndrome
0.731 0.269 0.000
C80 Malignant neoplasm without specification of site
0.731 0.269 0.000
L03.1 Cellulitis of other parts of limb
0.729 0.271 0.000
S00-S09 Injuries to the head
0.725 0.275 0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)
0.720 0.280 0.000
I44.0 Atrioventricular block, first degree
0.720 0.280 0.000
D69.6 Thrombocytopenia, unspecified
0.720 0.280 0.000
K85.9 Acute pancreatitis, unspecified
0.720 0.280 0.000
M51.9 Intervertebral disk disorder, unspecified
0.720 0.280 0.000
K86.3 Pseudocyst of pancreas
0.719 0.281 0.000
I05-I09 Chronic rheumatic heart diseases
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.283 0.000
M49 Spondylopathies in diseases classified elsewhere
0.716 0.283 0.000
M47.1 Other spondylosis with myelopathy
0.716 0.284 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.716 0.284 0.000
I47.2 Ventricular tachycardia
0.715 0.285 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.715 0.285 0.000
M53 Other dorsopathies, not elsewhere classified
0.715 0.285 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.714 0.285 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.714 0.286 0.000
C79.6 Secondary malignant neoplasm of ovary
0.714 0.286 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.714 0.286 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.714 0.286 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.713 0.287 0.000
F80-F89 Disorders of psychological development
0.713 0.287 0.000
F70-F79 Mental retardation
0.713 0.287 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.713 0.287 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.713 0.287 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.713 0.287 0.000
M47.84 Other spondylosis (Thoracic region)
0.713 0.287 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.713 0.287 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.713 0.287 0.000
I52 Other heart disorders in diseases classified elsewhere
0.712 0.288 0.000
I48 Atrial fibrillation and flutter
0.712 0.288 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.712 0.288 0.000
I41 Myocarditis in diseases classified elsewhere
0.712 0.288 0.000
I40 Acute myocarditis
0.712 0.288 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.712 0.288 0.000
I37 Pulmonary valve disorders
0.712 0.288 0.000
I36 Nonrheumatic tricuspid valve disorders
0.712 0.288 0.000
I32 Pericarditis in diseases classified elsewhere
0.712 0.288 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.711 0.289 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.711 0.289 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.711 0.289 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.711 0.289 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.711 0.289 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.711 0.289 0.000
F11 Mental and behavioural disorders due to use of opioids
0.711 0.289 0.000
D27 Benign neoplasm of ovary
0.711 0.289 0.000
I25.6 Silent myocardial ischaemia
0.710 0.290 0.000
I25.4 Coronary artery aneurysm
0.710 0.290 0.000
I25.3 Aneurysm of heart
0.710 0.290 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.710 0.290 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.710 0.290 0.000
K83 Other diseases of biliary tract
0.710 0.290 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.710 0.290 0.000
F60-F69 Disorders of adult personality and behaviour
0.710 0.290 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.709 0.291 0.000
M47.89 Other spondylosis (Site unspecified)
0.709 0.291 0.000
D22.5 Melanocytic naevi of trunk
0.707 0.293 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.706 0.294 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.706 0.294 0.000
I71.0 Dissection of aorta [any part]
0.706 0.294 0.000
M54.8 Other dorsalgia
0.706 0.294 0.000
M54.0 Panniculitis affecting regions of neck and back
0.706 0.294 0.000
N17.9 Acute renal failure, unspecified
0.705 0.295 0.000
F10.9 Unspecified mental and behavioural disorder
0.703 0.296 0.000
F10.8 Other mental and behavioural disorders
0.703 0.296 0.000
F10.7 Residual and late-onset psychotic disorder
0.703 0.296 0.000
F10.6 Amnesic syndrome
0.703 0.296 0.000
F10.5 Psychotic disorder
0.703 0.296 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.703 0.297 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.702 0.298 0.000
I77.1 Stricture of artery
0.702 0.298 0.000
D32 Benign neoplasm of meninges
0.702 0.298 0.000
I46 Cardiac arrest
0.700 0.300 0.000
I31 Other diseases of pericardium
0.699 0.301 0.000
D55-D59 Haemolytic anaemias
0.699 0.301 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.699 0.301 0.000
N18.8 Other chronic renal failure
0.698 0.302 0.000
N18.2 Chronic kidney disease, stage 2
0.698 0.302 0.000
N18.1 Chronic kidney disease, stage 1
0.698 0.302 0.000
Chapter VI Diseases of the nervous system
0.698 0.302 0.000
I95 Hypotension
0.697 0.303 0.000
M54.56 Low back pain (Lumbar region)
0.697 0.303 0.000
F99-F99 Unspecified mental disorder
0.696 0.304 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.696 0.304 0.000
I33 Acute and subacute endocarditis
0.696 0.304 0.000
D10 Benign neoplasm of mouth and pharynx
0.695 0.305 0.000
M45 Ankylosing spondylitis
0.694 0.306 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.693 0.306 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.693 0.307 0.000
M85 Other disorders of bone density and structure
0.693 0.307 0.000
D68.0 Von Willebrand's disease
0.692 0.308 0.000
I38 Endocarditis, valve unspecified
0.692 0.308 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.691 0.309 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.690 0.310 0.000
M51.3 Other specified intervertebral disk degeneration
0.689 0.311 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.689 0.311 0.000
M51.4 Schmorl's nodes
0.689 0.311 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.688 0.312 0.000
I70 Atherosclerosis
0.687 0.312 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.685 0.314 0.000
D67 Hereditary factor IX deficiency
0.685 0.315 0.000
D66 Hereditary factor VIII deficiency
0.685 0.315 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.685 0.315 0.000
M51.8 Other specified intervertebral disk disorders
0.685 0.315 0.000
M15 Polyarthrosis
0.684 0.316 0.000
M54.55 Low back pain (Thoracolumbar region)
0.684 0.316 0.000
M54.54 Low back pain-Thoracic
0.684 0.316 0.000
M54.53 Low back pain-Cervicothoracic
0.684 0.316 0.000
M54.52 Low back pain-Cervical
0.684 0.316 0.000
M54.51 Low back pain-Occipit-atl-axl
0.684 0.316 0.000
I72 Other aneurysm
0.682 0.318 0.000
D68.8 Other specified coagulation defects
0.680 0.320 0.000
I27 Other pulmonary heart diseases
0.680 0.320 0.000
C85.1 B-cell lymphoma, unspecified
0.679 0.321 0.000
D75.2 Essential thrombocytosis
0.678 0.322 0.000
M05-M14 Inflammatory polyarthropathies
0.678 0.322 0.000
C34.3 Lower lobe, bronchus or lung
0.677 0.323 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.676 0.324 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.676 0.324 0.000
N18.5 Chronic kidney disease, stage 5
0.673 0.327 0.000
C32 Malignant neoplasm of larynx
0.673 0.327 0.000
I35.9 Aortic valve disorder, unspecified
0.672 0.328 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.671 0.329 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.671 0.329 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.670 0.330 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.670 0.330 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.669 0.331 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.669 0.331 0.000
I24.8 Other forms of acute ischaemic heart disease
0.669 0.331 0.000
K86.8 Other specified diseases of pancreas
0.668 0.332 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.667 0.333 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.666 0.333 0.000
I74.8 Embolism and thrombosis of other arteries
0.666 0.333 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.666 0.333 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.666 0.333 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.666 0.333 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.666 0.333 0.000
N25-N29 Other disorders of kidney and ureter
0.666 0.334 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.665 0.334 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.665 0.334 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.665 0.334 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.665 0.334 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.665 0.334 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.665 0.334 0.000
I42.2 Other hypertrophic cardiomyopathy
0.665 0.335 0.000
D30 Benign neoplasm of urinary organs
0.665 0.335 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.663 0.337 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.663 0.337 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.663 0.337 0.000
C66 Malignant neoplasm of ureter
0.663 0.337 0.000
C65 Malignant neoplasm of renal pelvis
0.663 0.337 0.000
I44.1 Atrioventricular block, second degree
0.663 0.337 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.663 0.337 0.000
L40-L45 Papulosquamous disorders
0.663 0.337 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.661 0.339 0.000
K82.4 Cholesterolosis of gallbladder
0.661 0.339 0.000
I44.6 Other and unspecified fascicular block
0.660 0.340 0.000
I44.5 Left posterior fascicular block
0.660 0.340 0.000
I44.4 Left anterior fascicular block
0.660 0.340 0.000
I44.3 Other and unspecified atrioventricular block
0.660 0.340 0.000
I42.8 Other cardiomyopathies
0.660 0.340 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.660 0.340 0.000
I42.6 Alcoholic cardiomyopathy
0.660 0.340 0.000
I42.5 Other restrictive cardiomyopathy
0.660 0.340 0.000
I42.4 Endocardial fibroelastosis
0.660 0.340 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.660 0.340 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.660 0.340 0.000
M84.0 Malunion of fracture
0.659 0.341 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.658 0.342 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.658 0.342 0.000
C31 Malignant neoplasm of accessory sinuses
0.658 0.342 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.658 0.342 0.000
C37 Malignant neoplasm of thymus
0.658 0.342 0.000
C33 Malignant neoplasm of trachea
0.658 0.342 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.658 0.342 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.658 0.342 0.000
D41.4 Bladder
0.658 0.342 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.658 0.342 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.657 0.343 0.000
F17.9 Unspecified mental and behavioural disorder
0.657 0.343 0.000
F17.8 Other mental and behavioural disorders
0.657 0.343 0.000
F17.7 Residual and late-onset psychotic disorder
0.657 0.343 0.000
F17.6 Amnesic syndrome
0.657 0.343 0.000
F17.5 Psychotic disorder
0.657 0.343 0.000
F17.4 Withdrawal state with delirium
0.657 0.343 0.000
F17.3 Withdrawal state
0.657 0.343 0.000
F17.0 Acute intoxication
0.657 0.343 0.000
I73 Other peripheral vascular diseases
0.656 0.344 0.000
Chapter XX External causes of morbidity and mortality
0.655 0.345 0.000
D11 Benign neoplasm of major salivary glands
0.655 0.345 0.000
L10-L14 Bullous disorders
0.655 0.345 0.000
M48.0 Spinal stenosis
0.654 0.346 0.000
I45.9 Conduction disorder, unspecified
0.654 0.346 0.000
D22.4 Melanocytic naevi of scalp and neck
0.653 0.347 0.000
M54.1 Radiculopathy
0.653 0.347 0.000
N03.9 Unspecified
0.653 0.347 0.000
C01 Malignant neoplasm of base of tongue
0.653 0.347 0.000
N88 Other noninflammatory disorders of cervix uteri
0.651 0.349 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.650 0.350 0.000
M80 Osteoporosis with pathological fracture
0.650 0.350 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.648 0.352 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.648 0.352 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.648 0.352 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.648 0.352 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.648 0.352 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.648 0.352 0.000
M89 Other disorders of bone
0.647 0.352 0.000
M54.3 Sciatica
0.647 0.353 0.000
S70 Superficial injury of hip and thigh
0.647 0.353 0.000
D46 Myelodysplastic syndromes
0.645 0.355 0.000
D68.6 Other Thrombophilia
0.645 0.355 0.000
D68.4 Acquired coagulation factor deficiency
0.645 0.355 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.645 0.355 0.000
D68.1 Hereditary factor XI deficiency
0.645 0.355 0.000
H90-H95 Other disorders of ear
0.644 0.356 0.000
M20-M25 Other joint disorders
0.644 0.356 0.000
S10-S19 Injuries to the neck
0.644 0.356 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.643 0.357 0.000
S81 Open wound of lower leg
0.641 0.359 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.641 0.359 0.000
M16.3 Other dysplastic coxarthrosis
0.641 0.359 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.640 0.360 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.640 0.360 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.640 0.360 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.640 0.360 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.640 0.360 0.000
C71 Malignant neoplasm of brain
0.640 0.360 0.000
D73 Diseases of spleen
0.640 0.360 0.000
M54.22 Cervicalgia (Cervical region)
0.639 0.361 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.638 0.362 0.000
D74 Methaemoglobinaemia
0.638 0.362 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.638 0.362 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.638 0.362 0.000
L50-L54 Urticaria and erythema
0.637 0.363 0.000
D69.9 Haemorrhagic condition, unspecified
0.637 0.363 0.000
D69.8 Other specified haemorrhagic conditions
0.637 0.363 0.000
D69.5 Secondary thrombocytopenia
0.637 0.363 0.000
D69.4 Other primary thrombocytopenia
0.637 0.363 0.000
D69.2 Other nonthrombocytopenic purpura
0.637 0.363 0.000
D69.1 Qualitative platelet defects
0.637 0.363 0.000
D69.0 Allergic purpura
0.637 0.363 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.637 0.363 0.000
K82.8 Other specified diseases of gallbladder
0.637 0.363 0.000
L08 Other local infections of skin and subcutaneous tissue
0.637 0.363 0.000
M19.8 Other specified arthrosis
0.637 0.363 0.000
M19.2 Other secondary arthrosis
0.637 0.363 0.000
F12.1 Harmful use
0.637 0.363 0.000
M90 Osteopathies in diseases classified elsewhere
0.636 0.364 0.000
M87 Osteonecrosis
0.636 0.364 0.000
N85.2 Hypertrophy of uterus
0.636 0.364 0.000
M19.1 Posttraumatic arthrosis of other joints
0.636 0.364 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.635 0.365 0.000
M50 Cervical disk disorders
0.633 0.366 0.000
K70-K77 Diseases of liver
0.631 0.369 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.631 0.369 0.000
M83 Adult osteomalacia
0.631 0.369 0.000
M82 Osteoporosis in diseases classified elsewhere
0.631 0.369 0.000
D18 Haemangioma and lymphangioma, any site
0.630 0.370 0.000
I47.1 Supraventricular tachycardia
0.630 0.370 0.000
D22.9 Melanocytic naevi, unspecified
0.629 0.370 0.000
N85.0 Endometrial glandular hyperplasia
0.628 0.372 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.628 0.372 0.000
D31 Benign neoplasm of eye and adnexa
0.628 0.372 0.000
D29 Benign neoplasm of male genital organs
0.628 0.372 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.628 0.372 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.628 0.372 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.628 0.372 0.000
D19 Benign neoplasm of mesothelial tissue
0.628 0.372 0.000
D16 Benign neoplasm of bone and articular cartilage
0.628 0.372 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.628 0.372 0.000
I21.9 Acute myocardial infarction, unspecified
0.626 0.374 0.000
C15-C26 Malignant neoplasms of digestive organs
0.626 0.374 0.000
I78 Diseases of capillaries
0.625 0.374 0.000
C78.2 Secondary malignant neoplasm of pleura
0.625 0.375 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.625 0.375 0.000
M42 Spinal osteochondrosis
0.624 0.376 0.000
M40 Kyphosis and lordosis
0.624 0.376 0.000
N05 Unspecified nephritic syndrome
0.624 0.376 0.000
L60 Nail disorders
0.623 0.377 0.000
D72 Other disorders of white blood cells
0.623 0.377 0.000
I28 Other diseases of pulmonary vessels
0.623 0.377 0.000
D80-D89 Certain disorders involving the immune mechanism
0.622 0.378 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.621 0.379 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.621 0.379 0.000
I51.9 Heart disease, unspecified
0.620 0.380 0.000
D26.9 Uterus, unspecified
0.620 0.380 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.620 0.380 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.620 0.380 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.620 0.380 0.000
K83.8 Other specified diseases of biliary tract
0.619 0.381 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.618 0.382 0.000
L30 Other dermatitis
0.617 0.383 0.000
I47.0 Reentry ventricular arrhythmia
0.616 0.383 0.000
C91 Lymphoid leukaemia
0.616 0.384 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.616 0.384 0.000
D75.1 Secondary polycythaemia
0.616 0.384 0.000
N88.8 Other specified noninflammatory disorders of cervix uteri
0.615 0.385 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.615 0.385 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.615 0.385 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.615 0.385 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.615 0.385 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.614 0.386 0.000
C34.8 Overlapping lesion of bronchus and lung
0.614 0.386 0.000
C34.2 Middle lobe, bronchus or lung
0.614 0.386 0.000
C34.0 Main bronchus
0.614 0.386 0.000
S02 Fracture of skull and facial bones
0.614 0.386 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.613 0.387 0.000
M19.98 Arthrosis, unspecified (Other)
0.613 0.387 0.000
N02 Recurrent and persistent haematuria
0.613 0.387 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.612 0.388 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.612 0.388 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.612 0.388 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.612 0.388 0.000
M54.27 Cervicalgia-Lumbosacral
0.612 0.388 0.000
M54.26 Cervicalgia-Lumbar
0.612 0.388 0.000
M54.25 Cervicalgia-Thoracolumbar
0.612 0.388 0.000
M54.24 Cervicalgia-Thoracic
0.612 0.388 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.612 0.388 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.612 0.388 0.000
M54.20 Cervicalgia-Mult site
0.612 0.388 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.611 0.389 0.000
L27 Dermatitis due to substances taken internally
0.611 0.389 0.000
D22.0 Melanocytic naevi of lip
0.611 0.389 0.000
Q60-Q64 Congenital malformations of the urinary system
0.608 0.392 0.000
T33-T35 Frostbite
0.607 0.392 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.607 0.392 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.607 0.392 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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