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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77609157
log Bayes Factor = 17.2746
Chromosome 6   position 150,672,660  (GRCh37) Explore rs77609157 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
N80-N98 Noninflammatory disorders of female genital tract
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
N17-N19 Renal failure
0.996 0.004 0.000
N10-N16 Renal tubulo-interstitial diseases
0.994 0.006 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.993 0.007 0.000
I60-I69 Cerebrovascular diseases
0.992 0.008 0.000
Chapter IX Diseases of the circulatory system
0.992 0.008 0.000
B95-B98 Bacterial, viral and other infectious agents
0.990 0.010 0.000
I63 Cerebral infarction
0.989 0.011 0.000
N30-N39 Other diseases of urinary system
0.988 0.012 0.000
I63.9 Cerebral infarction, unspecified
0.986 0.014 0.000
Chapter XI Diseases of the digestive system
0.983 0.017 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.983 0.017 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.979 0.021 0.000
N30 Cystitis
0.976 0.024 0.000
N18 Chronic renal failure
0.975 0.025 0.000
M20-M25 Other joint disorders
0.975 0.025 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.971 0.029 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.968 0.032 0.000
N19 Unspecified renal failure
0.963 0.037 0.000
K50-K52 Noninfective enteritis and colitis
0.962 0.038 0.000
K55-K64 Other diseases of intestines
0.962 0.038 0.000
R42 Dizziness and giddiness
0.958 0.042 0.000
K52 Other non-infective gastro-enteritis and colitis
0.958 0.042 0.000
M23 Internal derangement of knee
0.956 0.044 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.953 0.047 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.952 0.048 0.000
Chapter VI Diseases of the nervous system
0.947 0.053 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.944 0.056 0.000
N72 Inflammatory disease of cervix uteri
0.942 0.058 0.000
N92 Excessive, frequent and irregular menstruation
0.940 0.060 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.939 0.061 0.000
K63 Other diseases of intestine
0.935 0.065 0.000
Chapter XX External causes of morbidity and mortality
0.933 0.067 0.000
I67 Other cerebrovascular diseases
0.927 0.073 0.000
K60 Fissure and fistula of anal and rectal regions
0.927 0.073 0.000
N93 Other abnormal uterine and vaginal bleeding
0.926 0.074 0.000
M23.3 Other meniscus derangements
0.925 0.075 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.924 0.076 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.923 0.077 0.000
A00-A09 Intestinal infectious diseases
0.922 0.078 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.916 0.084 0.000
N30.9 Cystitis, unspecified
0.916 0.084 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.909 0.091 0.000
R26 Abnormalities of gait and mobility
0.908 0.092 0.000
K60.1 Chronic anal fissure
0.906 0.094 0.000
M23.8 Other internal derangements of knee
0.903 0.097 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.902 0.098 0.000
N13 Obstructive and reflux uropathy
0.898 0.102 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.896 0.104 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.889 0.111 0.000
M24 Other specific joint derangements
0.888 0.112 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.882 0.118 0.000
K35-K38 Diseases of appendix
0.882 0.118 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.882 0.118 0.000
N39 Other disorders of urinary system
0.881 0.119 0.000
I69 Sequelae of cerebrovascular disease
0.878 0.122 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.877 0.123 0.000
R29.6 Tendency to fall, not elsewhere classified
0.872 0.128 0.000
K63.9 Disease of intestine, unspecified
0.872 0.128 0.000
N95 Menopausal and other perimenopausal disorders
0.870 0.130 0.000
Chapter VIII Diseases of the ear and mastoid process
0.869 0.131 0.000
K63.8 Other specified diseases of intestine
0.868 0.132 0.000
N18.0 End-stage renal disease
0.866 0.134 0.000
N92.6 Irregular menstruation, unspecified
0.865 0.135 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.865 0.135 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.864 0.136 0.000
I67.8 Other specified cerebrovascular diseases
0.864 0.136 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.860 0.140 0.000
N81 Female genital prolapse
0.860 0.140 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.859 0.141 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.857 0.143 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.857 0.143 0.000
N00-N08 Glomerular diseases
0.857 0.143 0.000
M40-M43 Deforming dorsopathies
0.855 0.145 0.000
N18.9 Chronic renal failure, unspecified
0.851 0.149 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.848 0.152 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.846 0.154 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.846 0.154 0.000
M50-M54 Other dorsopathies
0.846 0.154 0.000
S20-S29 Injuries to the thorax
0.844 0.156 0.000
S70-S79 Injuries to the hip and thigh
0.840 0.160 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.840 0.160 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.839 0.161 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.839 0.161 0.000
M45-M49 Spondylopathies
0.838 0.162 0.000
N39.0 Urinary tract infection, site not specified
0.835 0.165 0.000
T92 Sequelae of injuries of upper limb
0.834 0.166 0.000
G62 Other polyneuropathies
0.833 0.167 0.000
N30.8 Other cystitis
0.833 0.167 0.000
G90-G99 Other disorders of the nervous system
0.831 0.169 0.000
N30.3 Trigonitis
0.830 0.170 0.000
N18.5 Chronic kidney disease, stage 5
0.828 0.172 0.000
N10 Acute tubulo-interstitial nephritis
0.827 0.173 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.827 0.173 0.000
N18.4 Chronic kidney disease, stage 4
0.826 0.174 0.000
A04 Other bacterial intestinal infections
0.825 0.175 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.825 0.175 0.000
R30-R39 Symptoms and signs involving the urinary system
0.825 0.175 0.000
M05-M14 Inflammatory polyarthropathies
0.819 0.181 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.818 0.182 0.000
M70-M79 Other soft tissue disorders
0.817 0.183 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.817 0.183 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.815 0.185 0.000
I67.9 Cerebrovascular disease, unspecified
0.813 0.187 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.807 0.193 0.000
N88 Other noninflammatory disorders of cervix uteri
0.806 0.194 0.000
M24.1 Other articular cartilage disorders
0.805 0.195 0.000
B07 Viral warts
0.804 0.196 0.000
N30.2 Other chronic cystitis
0.803 0.197 0.000
K52.1 Toxic gastro-enteritis and colitis
0.801 0.199 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.799 0.201 0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum
0.798 0.202 0.000
G62.9 Polyneuropathy, unspecified
0.797 0.203 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.793 0.207 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.793 0.207 0.000
A08 Viral and other specified intestinal infections
0.792 0.208 0.000
W00-W19 Falls
0.791 0.208 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.791 0.209 0.000
M80-M85 Disorders of bone density and structure
0.791 0.209 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.790 0.210 0.000
B25-B34 Other viral diseases
0.789 0.211 0.000
N81.4 Uterovaginal prolapse, unspecified
0.788 0.212 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.787 0.212 0.000
N80 Endometriosis
0.786 0.214 0.000
K63.3 Ulcer of intestine
0.785 0.215 0.000
L20-L30 Dermatitis and eczema
0.785 0.215 0.000
N85.1 Endometrial adenomatous hyperplasia
0.785 0.215 0.000
K65-K67 Diseases of peritoneum
0.783 0.217 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.783 0.217 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.782 0.217 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.782 0.218 0.000
M60-M63 Disorders of muscles
0.781 0.219 0.000
I20-I25 Ischaemic heart diseases
0.781 0.219 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.781 0.219 0.000
N35 Urethral stricture
0.779 0.221 0.000
K59 Other functional intestinal disorders
0.779 0.221 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.778 0.222 0.000
Chapter V Mental and behavioural disorders
0.776 0.224 0.000
M65-M68 Disorders of synovium and tendon
0.775 0.225 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.775 0.225 0.000
K60.2 Anal fissure, unspecified
0.774 0.226 0.000
K40-K46 Hernia
0.769 0.231 0.000
I63.8 Other cerebral infarction
0.769 0.231 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.767 0.233 0.000
R45 Symptoms and signs involving emotional state
0.767 0.233 0.000
N39.9 Disorder of urinary system, unspecified
0.765 0.235 0.000
H65-H75 Diseases of middle ear and mastoid
0.765 0.235 0.000
M91-M94 Chondropathies
0.764 0.236 0.000
N83.0 Follicular cyst of ovary
0.762 0.238 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.762 0.238 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.762 0.238 0.000
R35 Polyuria
0.754 0.246 0.000
I05-I09 Chronic rheumatic heart diseases
0.754 0.246 0.000
K56.6 Other and unspecified intestinal obstruction
0.751 0.249 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.751 0.249 0.000
N94.1 Dyspareunia
0.751 0.249 0.000
M22 Disorders of patella
0.750 0.250 0.000
K37 Unspecified appendicitis
0.749 0.251 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.749 0.251 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.749 0.251 0.000
N93.0 Postcoital and contact bleeding
0.748 0.252 0.000
W50-W64 Exposure to animate mechanical forces
0.748 0.252 0.000
N99-N99 Other disorders of the genitourinary system
0.748 0.252 0.000
M31 Other necrotising vasculopathies
0.748 0.252 0.000
K63.1 Perforation of intestine (nontraumatic)
0.745 0.255 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.744 0.256 0.000
G70-G73 Diseases of myoneural junction and muscle
0.744 0.256 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.742 0.257 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.742 0.258 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.742 0.258 0.000
L03 Cellulitis
0.740 0.260 0.000
N76 Other inflammation of vagina and vulva
0.738 0.262 0.000
M21 Other acquired deformities of limbs
0.736 0.264 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.735 0.265 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.735 0.265 0.000
N30.0 Acute cystitis
0.735 0.265 0.000
M47 Spondylosis
0.734 0.266 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.732 0.268 0.000
M54 Dorsalgia
0.732 0.268 0.000
R13 Dysphagia
0.731 0.269 0.000
W20-W49 Exposure to inanimate mechanical forces
0.730 0.269 0.000
R15 Faecal incontinence
0.730 0.270 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.727 0.273 0.000
N90.5 Atrophy of vulva
0.727 0.273 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.726 0.274 0.000
G40-G47 Episodic and paroxysmal disorders
0.726 0.274 0.000
I62 Other nontraumatic intracranial haemorrhage
0.724 0.276 0.000
S90-S99 Injuries to the ankle and foot
0.724 0.276 0.000
T90 Sequelae of injuries of head
0.724 0.276 0.000
I20 Angina pectoris
0.724 0.276 0.000
S10-S19 Injuries to the neck
0.723 0.277 0.000
Q50-Q56 Congenital malformations of genital organs
0.722 0.278 0.000
N81.6 Rectocele
0.722 0.278 0.000
R12 Heartburn
0.722 0.278 0.000
S72 Fracture of femur
0.721 0.278 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.719 0.281 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.719 0.281 0.000
R25 Abnormal involuntary movements
0.719 0.281 0.000
T79-T79 Certain early complications of trauma
0.718 0.282 0.000
K41 Femoral hernia
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N98 Complications associated with artificial fertilisation
0.717 0.283 0.000
N91 Absent, scanty and rare menstruation
0.717 0.283 0.000
N82 Fistulae involving female genital tract
0.717 0.283 0.000
N96 Habitual aborter
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
B15-B19 Viral hepatitis
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A80-A89 Viral infections of the central nervous system
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.716 0.284 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.715 0.285 0.000
N13.3 Other and unspecified hydronephrosis
0.715 0.285 0.000
N80.3 Endometriosis of pelvic peritoneum
0.715 0.285 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.713 0.287 0.000
R30 Pain associated with micturition
0.713 0.287 0.000
E20-E35 Disorders of other endocrine glands
0.713 0.287 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.712 0.288 0.000
N15 Other renal tubulo-interstitial diseases
0.712 0.288 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.712 0.288 0.000
N11 Chronic tubulo-interstitial nephritis
0.712 0.288 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.711 0.289 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.711 0.289 0.000
I00-I02 Acute rheumatic fever
0.711 0.289 0.000
N97 Female infertility
0.709 0.291 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.709 0.291 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.709 0.291 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.709 0.291 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.709 0.291 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.709 0.291 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.709 0.291 0.000
N37 Urethral disorders in diseases classified elsewhere
0.708 0.292 0.000
N34 Urethritis and urethral syndrome
0.708 0.292 0.000
N33 Bladder disorders in diseases classified elsewhere
0.708 0.292 0.000
T93 Sequelae of injuries of lower limb
0.708 0.292 0.000
I77 Other disorders of arteries and arterioles
0.707 0.293 0.000
K35 Acute appendicitis
0.707 0.293 0.000
N25-N29 Other disorders of kidney and ureter
0.707 0.293 0.000
N30.1 Interstitial cystitis (chronic)
0.707 0.293 0.000
R40 Somnolence, stupor and coma
0.707 0.293 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.706 0.294 0.000
N73 Other female pelvic inflammatory diseases
0.706 0.294 0.000
R46 Symptoms and signs involving appearance and behaviour
0.704 0.295 0.000
R43 Disturbances of smell and taste
0.704 0.295 0.000
N81.1 Cystocele
0.704 0.295 0.000
T66-T78 Other and unspecified effects of external causes
0.704 0.296 0.000
A30-A49 Other bacterial diseases
0.704 0.296 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.703 0.297 0.000
R47-R49 Symptoms and signs involving speech and voice
0.703 0.297 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.703 0.297 0.000
R29.4 Clicking hip
0.702 0.298 0.000
R29.3 Abnormal posture
0.702 0.298 0.000
R29.2 Abnormal reflex
0.702 0.298 0.000
R29.1 Meningismus
0.702 0.298 0.000
R29.0 Tetany
0.702 0.298 0.000
I69.3 Sequelae of cerebral infarction
0.702 0.298 0.000
N02 Recurrent and persistent haematuria
0.701 0.299 0.000
N36 Other disorders of urethra
0.700 0.300 0.000
I60 Subarachnoid haemorrhage
0.700 0.300 0.000
N30.4 Irradiation cystitis
0.699 0.300 0.000
N18.8 Other chronic renal failure
0.699 0.301 0.000
N18.2 Chronic kidney disease, stage 2
0.699 0.301 0.000
N18.1 Chronic kidney disease, stage 1
0.699 0.301 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.699 0.301 0.000
M34 Systemic sclerosis
0.699 0.301 0.000
M33 Dermatopolymyositis
0.699 0.301 0.000
M32 Systemic lupus erythematosus
0.699 0.301 0.000
M30 Polyarteritis nodosa and related conditions
0.699 0.301 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.699 0.301 0.000
A08.4 Viral intestinal infection, unspecified
0.699 0.301 0.000
M43 Other deforming dorsopathies
0.698 0.301 0.000
R17 Unspecified jaundice
0.699 0.301 0.000
R44.1 Visual hallucinations
0.698 0.302 0.000
M41 Scoliosis
0.697 0.303 0.000
M10 Gout
0.697 0.303 0.000
M86-M90 Other osteopathies
0.696 0.304 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.695 0.304 0.000
N18.3 Chronic kidney disease, stage 3
0.695 0.305 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.694 0.306 0.000
N71 Inflammatory disease of uterus, except cervix
0.694 0.306 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.691 0.309 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.690 0.310 0.000
S50-S59 Injuries to the elbow and forearm
0.690 0.310 0.000
K38 Other diseases of appendix
0.688 0.312 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.688 0.312 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.688 0.312 0.000
I20.8 Other forms of angina pectoris
0.687 0.313 0.000
N87 Dysplasia of cervix uteri
0.687 0.313 0.000
Y85 Sequelae of transport accidents
0.687 0.313 0.000
K52.3 Indeterminate colitis
0.686 0.313 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.686 0.313 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.686 0.313 0.000
M23.9 Internal derangement of knee, unspecified
0.685 0.315 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.685 0.315 0.000
M23.5 Chronic instability of knee
0.685 0.315 0.000
M23.4 Loose body in knee
0.685 0.315 0.000
M23.1 Discoid meniscus (congenital)
0.685 0.315 0.000
M23.0 Cystic meniscus
0.685 0.315 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.685 0.315 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.684 0.316 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.683 0.317 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.683 0.317 0.000
T33-T35 Frostbite
0.683 0.317 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.683 0.317 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.683 0.317 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.683 0.317 0.000
T00-T07 Injuries involving multiple body regions
0.683 0.317 0.000
K44 Diaphragmatic hernia
0.682 0.318 0.000
A04.5 Campylobacter enteritis
0.681 0.319 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.680 0.319 0.000
M24.0 Loose body in joint
0.680 0.320 0.000
S70 Superficial injury of hip and thigh
0.680 0.320 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.679 0.321 0.000
R14 Flatulence and related conditions
0.679 0.321 0.000
N89 Other noninflammatory disorders of vagina
0.678 0.322 0.000
S22.3 Fracture of rib
0.677 0.322 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.677 0.323 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.677 0.323 0.000
G81 Hemiplegia
0.676 0.323 0.000
N88.2 Stricture and stenosis of cervix uteri
0.676 0.324 0.000
Chapter II Neoplasms
0.675 0.325 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.674 0.325 0.000
N92.5 Other specified irregular menstruation
0.674 0.326 0.000
N92.2 Excessive menstruation at puberty
0.674 0.326 0.000
R27 Other lack of coordination
0.673 0.327 0.000
B35-B49 Mycoses
0.673 0.327 0.000
M53 Other dorsopathies, not elsewhere classified
0.671 0.329 0.000
K63.4 Enteroptosis
0.670 0.329 0.000
K63.2 Fistula of intestine
0.670 0.329 0.000
K63.0 Abscess of intestine
0.670 0.329 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.669 0.331 0.000
Y35-Y36 Legal intervention and operations of war
0.669 0.331 0.000
Y10-Y34 Event of undetermined intent
0.669 0.331 0.000
Y00-Y09 Assault
0.669 0.331 0.000
X85-X99 Assault
0.669 0.331 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.669 0.331 0.000
X50-X57 Overexertion, travel and privation
0.669 0.331 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.669 0.331 0.000
X30-X39 Exposure to forces of nature
0.669 0.331 0.000
X20-X29 Contact with venomous animals and plants
0.669 0.331 0.000
X10-X19 Contact with heat and hot substances
0.669 0.331 0.000
X00-X09 Exposure to smoke, fire and flames
0.669 0.331 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.669 0.331 0.000
W75-W84 Other accidental threats to breathing
0.669 0.331 0.000
W65-W74 Accidental drowning and submersion
0.669 0.331 0.000
V98-V99 Other and unspecified transport accidents
0.669 0.331 0.000
V95-V97 Air and space transport accidents
0.669 0.331 0.000
V90-V94 Water transport accidents
0.669 0.331 0.000
V80-V89 Other land transport accidents
0.669 0.331 0.000
V70-V79 Bus occupant injured in transport accident
0.669 0.331 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.669 0.331 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.669 0.331 0.000
V40-V49 Car occupant injured in transport accident
0.669 0.331 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.669 0.331 0.000
V20-V29 Motorcycle rider injured in transport accident
0.669 0.331 0.000
V01-V09 Pedestrian injured in transport accident
0.669 0.331 0.000
R39 Other symptoms and signs involving the urinary system
0.669 0.331 0.000
G95 Other diseases of spinal cord
0.668 0.331 0.000
S80-S89 Injuries to the knee and lower leg
0.668 0.332 0.000
V10-V19 Pedal cyclist injured in transport accident
0.667 0.333 0.000
L03.9 Cellulitis, unspecified
0.665 0.335 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.665 0.335 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.665 0.335 0.000
I67.5 Moyamoya disease
0.665 0.335 0.000
I67.4 Hypertensive encephalopathy
0.665 0.335 0.000
I67.3 Progressive vascular leukoencephalopathy
0.665 0.335 0.000
I67.2 Cerebral atherosclerosis
0.665 0.335 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.665 0.335 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.665 0.335 0.000
K60.5 Anorectal fistula
0.665 0.335 0.000
K60.4 Rectal fistula
0.665 0.335 0.000
K60.0 Acute anal fissure
0.665 0.335 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.664 0.336 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.663 0.337 0.000
M23.37 Other meniscus derangements-Capsular lig
0.663 0.337 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.663 0.337 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.663 0.337 0.000
L28 Lichen simplex chronicus and prurigo
0.663 0.337 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.662 0.338 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.662 0.338 0.000
N85.7 Haematometra
0.662 0.338 0.000
N85.6 Intra-uterine synechiae
0.662 0.338 0.000
N85.5 Inversion of uterus
0.662 0.338 0.000
N85.3 Subinvolution of uterus
0.662 0.338 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.662 0.338 0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.662 0.338 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.662 0.338 0.000
A07 Other protozoal intestinal diseases
0.661 0.339 0.000
A06 Amoebiasis
0.661 0.339 0.000
A05 Other bacterial foodborne intoxications
0.661 0.339 0.000
A03 Shigellosis
0.661 0.339 0.000
A02 Other Salmonella infections
0.661 0.339 0.000
A01 Typhoid and paratyphoid fevers
0.661 0.339 0.000
A00 Cholera
0.661 0.339 0.000
N85.2 Hypertrophy of uterus
0.660 0.340 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.659 0.341 0.000
N95.0 Postmenopausal bleeding
0.659 0.341 0.000
H73 Other disorders of tympanic membrane
0.659 0.341 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.658 0.341 0.000
N75 Diseases of Bartholin's gland
0.658 0.342 0.000
H90-H95 Other disorders of ear
0.658 0.342 0.000
N90.7 Vulvar cyst
0.658 0.342 0.000
R90.0 Intracranial space-occupying lesion
0.657 0.343 0.000
G40 Epilepsy
0.657 0.343 0.000
L10-L14 Bullous disorders
0.657 0.343 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.656 0.344 0.000
K65 Peritonitis
0.656 0.344 0.000
B02 Zoster [herpes zoster]
0.656 0.344 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.655 0.345 0.000
R87 Abnormal findings in specimens from female genital organs
0.655 0.345 0.000
T87 Complications peculiar to reattachment and amputation
0.654 0.346 0.000
I61 Intracerebral haemorrhage
0.654 0.346 0.000
M80 Osteoporosis with pathological fracture
0.654 0.346 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.653 0.347 0.000
N86 Erosion and ectropion of cervix uteri
0.653 0.347 0.000
M35 Other systemic involvement of connective tissue
0.652 0.347 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.652 0.348 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.652 0.348 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.652 0.348 0.000
M54.9 Dorsalgia, unspecified
0.651 0.349 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.651 0.349 0.000
R26.3 Immobility
0.651 0.349 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.651 0.349 0.000
R26.1 Paralytic gait
0.651 0.349 0.000
R26.0 Ataxic gait
0.651 0.349 0.000
E16 Other disorders of pancreatic internal secretion
0.651 0.349 0.000
M46 Other inflammatory spondylopathies
0.650 0.350 0.000
G93 Other disorders of brain
0.650 0.350 0.000
S27 Injury of other and unspecified intrathoracic organs
0.649 0.351 0.000
N92.4 Excessive bleeding in the premenopausal period
0.649 0.351 0.000
F30-F39 Mood [affective] disorders
0.649 0.351 0.000
N95.1 Menopausal and female climacteric states
0.647 0.353 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.647 0.353 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.647 0.353 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.647 0.353 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.647 0.353 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.647 0.353 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.647 0.353 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.647 0.353 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.647 0.353 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.647 0.353 0.000
T98 Sequelae of other and unspecified effects of external causes
0.647 0.353 0.000
T95 Sequelae of burns, corrosions and frostbite
0.647 0.353 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.647 0.353 0.000
T91 Sequelae of injuries of neck and trunk
0.647 0.353 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.647 0.353 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.647 0.353 0.000
N85.0 Endometrial glandular hyperplasia
0.645 0.355 0.000
L05 Pilonidal cyst
0.644 0.356 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.644 0.356 0.000
N13.6 Pyonephrosis
0.644 0.356 0.000
N13.4 Hydroureter
0.644 0.356 0.000
N04 Nephrotic syndrome
0.643 0.356 0.000
C34 Malignant neoplasm of bronchus and lung
0.643 0.357 0.000
M25 Other joint disorders, not elsewhere classified
0.643 0.357 0.000
M67 Other disorders of synovium and tendon
0.643 0.357 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.642 0.358 0.000
N90.6 Hypertrophy of vulva
0.642 0.358 0.000
N90.3 Dysplasia of vulva, unspecified
0.642 0.358 0.000
N90.2 Severe vulvar dysplasia, not elsewhere classified
0.642 0.358 0.000
N90.1 Moderate vulvar dysplasia
0.642 0.358 0.000
N90.0 Mild vulvar dysplasia
0.642 0.358 0.000
G61 Inflammatory polyneuropathy
0.639 0.361 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.639 0.361 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.638 0.361 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.638 0.362 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.637 0.362 0.000
B06 Rubella [German measles]
0.637 0.362 0.000
B05 Measles
0.637 0.362 0.000
B01 Varicella [chickenpox]
0.637 0.362 0.000
B00 Herpesviral [herpes simplex] infections
0.637 0.362 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.637 0.362 0.000
B04 Monkeypox
0.637 0.362 0.000
B03 Smallpox
0.637 0.362 0.000
M24.9 Joint derangement, unspecified
0.636 0.363 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.636 0.363 0.000
M24.7 Protrusio acetabuli
0.636 0.363 0.000
M24.6 Ankylosis of joint
0.636 0.363 0.000
M24.5 Contracture of joint
0.636 0.363 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.636 0.363 0.000
M24.2 Disorder of ligament
0.636 0.363 0.000
R80 Isolated proteinuria
0.635 0.364 0.000
N13.8 Other obstructive and reflux uropathy
0.634 0.366 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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