TreeWAS – Variant ID: rs7776258

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
O70 Perineal laceration during delivery	0.027	0.973
O70.2 Third degree perineal laceration during delivery	0.026	0.974
O60-O75 Complications of labour and delivery	0.025	0.975
O70.0 First degree perineal laceration during delivery	0.024	0.976
E10.9 Without complications	0.021	0.979
Chapter XV Pregnancy, childbirth and the puerperium	0.021	0.979
O70.9 Perineal laceration during delivery, unspecified	0.021	0.979
E10 Insulin-dependent diabetes mellitus	0.021	0.979
E10-E14 Diabetes mellitus	0.021	0.979
O68 Labour and delivery complicated by foetal stress [distress]	0.021	0.979
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.021	0.979
E14.9 Without complications	0.021	0.979
O69 Labour and delivery complicated by umbilical cord complications	0.021	0.979
E14 Unspecified diabetes mellitus	0.020	0.980
O70.1 Second degree perineal laceration during delivery	0.020	0.980
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.020	0.980
O70.3 Fourth degree perineal laceration during delivery	0.019	0.981
O36 Maternal care for other known or suspected foetal problems	0.019	0.981
O63 Long labour	0.018	0.982
O73 Retained placenta and membranes, without haemorrhage	0.018	0.982
O75 Other complications of labour and delivery, not elsewhere classified	0.018	0.982
O74 Complications of anaesthesia during labour and delivery	0.018	0.982
O71 Other obstetric trauma	0.018	0.982
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.018	0.982
O65 Obstructed labour due to maternal pelvic abnormality	0.018	0.982
O62 Abnormalities of forces of labour	0.018	0.982
O61 Failed induction of labour	0.018	0.982
O60 Preterm delivery	0.018	0.982
O47 False labour	0.018	0.982
O66 Other obstructed labour	0.018	0.982
O72 Postpartum haemorrhage	0.018	0.982
O64 Obstructed labour due to malposition and malpresentation of foetus	0.018	0.982
E10.3 With ophthalmic complications	0.017	0.983
E11 Non-insulin-dependent diabetes mellitus	0.017	0.983
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.017	0.983
O69.8 Labour and delivery complicated by other cord complications	0.017	0.983
O41 Other disorders of amniotic fluid and membranes	0.017	0.983
O48 Prolonged pregnancy	0.017	0.983
O69.2 Labour and delivery complicated by other cord entanglement	0.016	0.983
O36.8 Maternal care for other specified foetal problems	0.016	0.984
O30 Multiple gestation	0.016	0.984
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.016	0.984
O36.5 Maternal care for poor foetal growth	0.016	0.984
O47.0 False labour before 37 completed weeks of gestation	0.016	0.984
Chapter IV Endocrine, nutritional and metabolic diseases	0.016	0.984
O85-O92 Complications predominantly related to the puerperium	0.015	0.984
O20-O29 Other maternal disorders predominantly related to pregnancy	0.016	0.984
E10.8 With unspecified complications	0.015	0.984
E10.7 With multiple complications	0.015	0.984
E10.6 With other specified complications	0.015	0.984
E10.5 With peripheral circulatory complications	0.015	0.984
E10.4 With neurological complications	0.015	0.984
E10.2 With renal complications	0.015	0.984
E10.1 With ketoacidosis	0.015	0.984
E10.0 With coma	0.015	0.984
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.015	0.985
E13 Other specified diabetes mellitus	0.015	0.985
E12 Malnutrition-related diabetes mellitus	0.015	0.985
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.015	0.985
Chapter XX External causes of morbidity and mortality	0.015	0.985
E11.2 With renal complications	0.015	0.985
D70 Agranulocytosis	0.015	0.985
O00-O08 Pregnancy with abortive outcome	0.015	0.985
O45 Premature separation of placenta [abruptio placentae]	0.015	0.985
O44 Placenta praevia	0.015	0.985
O43 Placental disorders	0.015	0.985
O35 Maternal care for known or suspected foetal abnormality and damage	0.015	0.985
O33 Maternal care for known or suspected disproportion	0.015	0.985
O31 Complications specific to multiple gestation	0.015	0.985
O40 Polyhydramnios	0.015	0.985
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.015	0.985
O69.9 Labour and delivery complicated by cord complication, unspecified	0.015	0.985
O69.5 Labour and delivery complicated by vascular lesion of cord	0.015	0.985
O69.4 Labour and delivery complicated by vasa praevia	0.015	0.985
O69.3 Labour and delivery complicated by short cord	0.015	0.985
O69.0 Labour and delivery complicated by prolapse of cord	0.015	0.985
D70-D77 Other diseases of blood and blood-forming organs	0.015	0.985
E14.8 With unspecified complications	0.015	0.985
E14.7 With multiple complications	0.015	0.985
E14.6 With other specified complications	0.015	0.985
E14.5 With peripheral circulatory complications	0.015	0.985
E14.4 With neurological complications	0.015	0.985
E14.2 Withrenal complications	0.015	0.985
E14.1 With ketoacidosis	0.015	0.985
E14.0 With coma	0.015	0.985
O32 Maternal care for known or suspected malpresentation of foetus	0.015	0.985
O16 Unspecified maternal hypertension	0.015	0.985
O46 Antepartum haemorrhage, not elsewhere classified	0.015	0.985
# Top node	0.015	0.985
E11.3 With ophthalmic complications	0.015	0.985
Chapter V Mental and behavioural disorders	0.015	0.985
O63.9 Long labour, unspecified	0.014	0.986
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.014	0.986
O69.1 Labour and delivery complicated by cord around neck, with compression	0.014	0.986
O42 Premature rupture of membranes	0.014	0.986
E14.3 With ophthalmic complications	0.014	0.986
O47.1 False labour at or after 37 completed weeks of gestation	0.014	0.986
O36.9 Maternal care for foetal problem, unspecified	0.014	0.986
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.014	0.986
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.014	0.986
O36.6 Maternal care for excessive foetal growth	0.014	0.986
O36.4 Maternal care for intra-uterine death	0.014	0.986
O36.3 Maternal care for signs of foetal hypoxia	0.014	0.986
O36.2 Maternal care for hydrops foetalis	0.014	0.986
O36.1 Maternal care for other isoimmunisation	0.014	0.986
O41.0 Oligohydramnios	0.014	0.986
F40-F48 Neurotic, stress-related and somatoform disorders	0.014	0.986
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.014	0.986
O73.0 Retained placenta, without haemorrhage	0.013	0.986
E11.4 With neurological complications	0.013	0.986
O63.2 Delayed delivery of second twin, triplet, etc.	0.013	0.987
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.013	0.987
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.013	0.987
O30.0 Twin pregnancy	0.013	0.987
O60.3 Preterm delivery without spontaneous labour	0.013	0.987
O60.2 Preterm spontaneous labour with term delivery	0.013	0.987
O60.1 Preterm spontaneous labour with preterm delivery	0.013	0.987
O60.0 Preterm labour without delivery	0.013	0.987
O61.9 Failed induction of labour, unspecified	0.013	0.987
O61.8 Other failed induction of labour	0.013	0.987
O61.1 Failed instrumental induction of labour	0.013	0.987
O61.0 Failed medical induction of labour	0.013	0.987
O62.9 Abnormality of forces of labour, unspecified	0.013	0.987
O62.8 Other abnormalities of forces of labour	0.013	0.987
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.013	0.987
O62.3 Precipitate labour	0.013	0.987
O62.2 Other uterine inertia	0.013	0.987
O62.1 Secondary uterine inertia	0.013	0.987
O62.0 Primary inadequate contractions	0.013	0.987
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.013	0.987
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.013	0.987
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.013	0.987
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.013	0.987
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.013	0.987
O65.2 Obstructed labour due to pelvic inlet contraction	0.013	0.987
O65.1 Obstructed labour due to generally contracted pelvis	0.013	0.987
O65.0 Obstructed labour due to deformed pelvis	0.013	0.987
O67.9 Intrapartum haemorrhage, unspecified	0.013	0.987
O67.8 Other intrapartum haemorrhage	0.013	0.987
O67.0 Intrapartum haemorrhage with coagulation defect	0.013	0.987
O71.9 Obstetric trauma, unspecified	0.013	0.987
O71.8 Other specified obstetric trauma	0.013	0.987
O71.7 Obstetric haematoma of pelvis	0.013	0.987
O71.6 Obstetric damage to pelvic joints and ligaments	0.013	0.987
O71.5 Other obstetric injury to pelvic organs	0.013	0.987
O71.4 Obstetric high vaginal laceration alone	0.013	0.987
O71.3 Obstetric laceration of cervix	0.013	0.987
O71.2 Postpartum inversion of uterus	0.013	0.987
O71.1 Rupture of uterus during labour	0.013	0.987
O71.0 Rupture of uterus before onset of labour	0.013	0.987
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.013	0.987
O74.8 Other complications of anaesthesia during labour and delivery	0.013	0.987
O74.7 Failed or difficult intubation during labour and delivery	0.013	0.987
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.013	0.987
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.013	0.987
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.013	0.987
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.013	0.987
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.013	0.987
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.013	0.987
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.013	0.987
O75.9 Complication of labour and delivery, unspecified	0.013	0.987
O75.8 Other specified complications of labour and delivery	0.013	0.987
O75.7 Vaginal delivery following previous Caesarean section	0.013	0.987
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.013	0.987
O75.5 Delayed delivery after artificial rupture of membranes	0.013	0.987
O75.4 Other complications of obstetric surgery and procedures	0.013	0.987
O75.3 Other infection during labour	0.013	0.987
O75.2 Pyrexia during labour, not elsewhere classified	0.013	0.987
O75.1 Shock during or following labour and delivery	0.013	0.987
O75.0 Maternal distress during labour and delivery	0.013	0.987
O66.9 Obstructed labour, unspecified	0.013	0.987
O66.8 Other specified obstructed labour	0.013	0.987
O66.4 Failed trial of labour, unspecified	0.013	0.987
O66.3 Obstructed labour due to other abnormalities of foetus	0.013	0.987
O66.2 Obstructed labour due to unusually large foetus	0.013	0.987
O66.1 Obstructed labour due to locked twins	0.013	0.987
O66.0 Obstructed labour due to shoulder dystocia	0.013	0.987
O72.3 Postpartum coagulation defects	0.013	0.987
O72.2 Delayed and secondary postpartum haemorrhage	0.013	0.987
O72.0 Third-stage haemorrhage	0.013	0.987
O94-O99 Other obstetric conditions, not elsewhere classified	0.013	0.987
W20-W49 Exposure to inanimate mechanical forces	0.013	0.987
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.013	0.987
O64.8 Obstructed labour due to other malposition and malpresentation	0.013	0.987
O64.5 Obstructed labour due to compound presentation	0.013	0.987
O64.4 Obstructed labour due to shoulder presentation	0.013	0.987
O64.3 Obstructed labour due to brow presentation	0.013	0.987
O64.2 Obstructed labour due to face presentation	0.013	0.987
O64.1 Obstructed labour due to breech presentation	0.013	0.987
D68 Other coagulation defects	0.013	0.987
O36.0 Maternal care for rhesus isoimmunisation	0.013	0.987
O63.1 Prolonged second stage (of labour)	0.013	0.987
E11.5 With peripheral circulatory complications	0.013	0.987
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.013	0.987
X50-X57 Overexertion, travel and privation	0.013	0.987
O63.0 Prolonged first stage (of labour)	0.013	0.987
O47.9 False labour, unspecified	0.013	0.987
O72.1 Other immediate postpartum haemorrhage	0.013	0.987
D50-D53 Nutritional anaemias	0.013	0.987
S00-S09 Injuries to the head	0.013	0.987
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.012	0.987
E11.8 With unspecified complications	0.012	0.987
E11.7 With multiple complications	0.012	0.987
E11.6 With other specified complications	0.012	0.987
E11.1 With ketoacidosis	0.012	0.987
E11.0 With coma	0.012	0.987
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.012	0.987
O80-O84 Delivery	0.012	0.987
O15 Eclampsia	0.012	0.988
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.012	0.988
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.012	0.988
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.012	0.988
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.012	0.988
E00-E07 Disorders of thyroid gland	0.012	0.988
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.012	0.988
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.012	0.988
O20 Haemorrhage in early pregnancy	0.012	0.988
O34 Maternal care for known or suspected abnormality of pelvic organs	0.012	0.988
N18.9 Chronic renal failure, unspecified	0.012	0.988
V10-V19 Pedal cyclist injured in transport accident	0.012	0.988
F41 Other anxiety disorders	0.012	0.988
E20-E35 Disorders of other endocrine glands	0.012	0.988
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.012	0.988
O41.8 Other specified disorders of amniotic fluid and membranes	0.012	0.988
O41.1 Infection of amniotic sac and membranes	0.012	0.988
O04 Medical abortion	0.012	0.988
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.012	0.988
O23 Infections of genito-urinary tract in pregnancy	0.012	0.988
O21 Excessive vomiting in pregnancy	0.012	0.988
O30.9 Multiple gestation, unspecified	0.012	0.988
O30.8 Other multiple gestation	0.012	0.988
O30.2 Quadruplet pregnancy	0.012	0.988
O30.1 Triplet pregnancy	0.012	0.988
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.012	0.988
F10.1 Harmful use	0.012	0.988
D72 Other disorders of white blood cells	0.012	0.988
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.012	0.988
O00 Ectopic pregnancy	0.012	0.988
E05 Thyrotoxicosis [hyperthyroidism]	0.012	0.988
N18 Chronic renal failure	0.012	0.988
I80 Phlebitis and thrombophlebitis	0.012	0.988
F10 Mental and behavioural disorders due to use of alcohol	0.012	0.988
F80-F89 Disorders of psychological development	0.012	0.988
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.012	0.988
E05.9 Thyrotoxicosis, unspecified	0.012	0.988
E40-E46 Malnutrition	0.012	0.988
D12.9 Anus and anal canal	0.012	0.988
F40 Phobic anxiety disorders	0.011	0.988
Chapter IX Diseases of the circulatory system	0.012	0.988
O29 Complications of anaesthesia during pregnancy	0.011	0.989
O28 Abnormal findings on antenatal screening of mother	0.011	0.989
O24 Diabetes mellitus in pregnancy	0.011	0.989
O22 Venous complications in pregnancy	0.011	0.989
O25 Malnutrition in pregnancy	0.011	0.989
O92 Other disorders of breast and lactation associated with childbirth	0.011	0.989
O91 Infections of breast associated with childbirth	0.011	0.989
O90 Complications of the puerperium, not elsewhere classified	0.011	0.989
O89 Complications of anaesthesia during the puerperium	0.011	0.989
O88 Obstetric embolism	0.011	0.989
O87 Venous complications in the puerperium	0.011	0.989
O86 Other puerperal infections	0.011	0.989
O85 Puerperal sepsis	0.011	0.989
S01 Open wound of head	0.011	0.989
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.011	0.989
F30-F39 Mood [affective] disorders	0.011	0.989
D51 Vitamin B12 deficiency anaemia	0.011	0.989
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.011	0.989
D12.3 Transverse colon	0.011	0.989
D55-D59 Haemolytic anaemias	0.011	0.989
D68.6 Other Thrombophilia	0.011	0.989
X50 Overexertion and strenuous or repetitive movements	0.011	0.989
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.011	0.989
E12.9 Without complications	0.011	0.989
E12.8 With unspecified complications	0.011	0.989
E12.7 With multiple complications	0.011	0.989
E12.6 With other specified complications	0.011	0.989
E12.5 With peripheral circulatory complications	0.011	0.989
E12.4 With neurological complications	0.011	0.989
E12.3 With ophthalmic complications	0.011	0.989
E12.2 With renal complications	0.011	0.989
E12.1 With ketoacidosis	0.011	0.989
E12.0 With coma	0.011	0.989
E13.9 Without complications	0.011	0.989
E13.8 With unspecified complications	0.011	0.989
E13.7 With multiple complications	0.011	0.989
E13.6 With other specified complications	0.011	0.989
E13.5 With peripheral circulatory complications	0.011	0.989
E13.4 With neurological complications	0.011	0.989
E13.3 With ophthalmic complications	0.011	0.989
E13.2 With renal complications	0.011	0.989
E13.1 With ketoacidosis	0.011	0.989
E13.0 With coma	0.011	0.989
S90-S99 Injuries to the ankle and foot	0.011	0.989
Chapter II Neoplasms	0.011	0.989
D12.4 Descending colon	0.011	0.989
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.011	0.989
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.011	0.989
Y35-Y36 Legal intervention and operations of war	0.011	0.989
Y10-Y34 Event of undetermined intent	0.011	0.989
Y00-Y09 Assault	0.011	0.989
X85-X99 Assault	0.011	0.989
X60-X84 Intentional self-harm	0.011	0.989
X58-X59 Accidental exposure to other and unspecified factors	0.011	0.989
X40-X49 Accidental poisoning by and exposure to noxious substances	0.011	0.989
X30-X39 Exposure to forces of nature	0.011	0.989
X20-X29 Contact with venomous animals and plants	0.011	0.989
X10-X19 Contact with heat and hot substances	0.011	0.989
X00-X09 Exposure to smoke, fire and flames	0.011	0.989
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.011	0.989
W75-W84 Other accidental threats to breathing	0.011	0.989
W65-W74 Accidental drowning and submersion	0.011	0.989
W50-W64 Exposure to animate mechanical forces	0.011	0.989
V98-V99 Other and unspecified transport accidents	0.011	0.989
V95-V97 Air and space transport accidents	0.011	0.989
V90-V94 Water transport accidents	0.011	0.989
V80-V89 Other land transport accidents	0.011	0.989
V70-V79 Bus occupant injured in transport accident	0.011	0.989
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.011	0.989
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.011	0.989
V40-V49 Car occupant injured in transport accident	0.011	0.989
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.011	0.989
V01-V09 Pedestrian injured in transport accident	0.011	0.989
O08 Complications following abortion and ectopic and molar pregnancy	0.011	0.989
O07 Failed attempted abortion	0.011	0.989
O06 Unspecified abortion	0.011	0.989
O05 Other abortion	0.011	0.989
O01 Hydatidiform mole	0.011	0.989
I12.0 Hypertensive renal disease with renal failure	0.011	0.989
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.011	0.989
O31.8 Other complications specific to multiple gestation	0.011	0.989
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.011	0.989
O31.1 Continuing pregnancy after abortion of one foetus or more	0.011	0.989
O31.0 Papyraceous foetus	0.011	0.989
O33.9 Maternal care for disproportion, unspecified	0.011	0.989
O33.8 Maternal care for disproportion of other origin	0.011	0.989
O33.7 Maternal care for disproportion due to other foetal deformities	0.011	0.989
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.011	0.989
O33.5 Maternal care for disproportion due to unusually large foetus	0.011	0.989
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.011	0.989
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.011	0.989
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.011	0.989
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.011	0.989
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.011	0.989
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.011	0.989
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.011	0.989
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.011	0.989
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.011	0.989
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.011	0.989
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.011	0.989
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.011	0.989
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.011	0.989
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.011	0.989
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.011	0.989
O43.9 Placental disorder, unspecified	0.011	0.989
O43.8 Other placental disorders	0.011	0.989
O43.2 Morbidly adherent placenta	0.011	0.989
O43.1 Malformation of placenta	0.011	0.989
O43.0 Placental transfusion syndromes	0.011	0.989
O44.1 Placenta praevia with haemorrhage	0.011	0.989
O44.0 Placenta praevia specified as without haemorrhage	0.011	0.989
O45.9 Premature separation of placenta, unspecified	0.011	0.989
O45.8 Other premature separation of placenta	0.011	0.989
O45.0 Premature separation of placenta with coagulation defect	0.011	0.989
W21 Striking against or struck by sports equipment	0.011	0.989
Y49 Psychotropic drugs, not elsewhere classified	0.011	0.989
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.011	0.989
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.011	0.989
D74 Methaemoglobinaemia	0.011	0.989
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.011	0.989
D71 Functional disorders of polymorphonuclear neutrophils	0.011	0.989
D80-D89 Certain disorders involving the immune mechanism	0.011	0.989
Chapter VIII Diseases of the ear and mastoid process	0.011	0.989
F43 Reaction to severe stress, and adjustment disorders	0.011	0.989
D68.8 Other specified coagulation defects	0.011	0.989
V20-V29 Motorcycle rider injured in transport accident	0.011	0.989
F60-F69 Disorders of adult personality and behaviour	0.011	0.989
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.011	0.989
O32.9 Maternal care for malpresentation of foetus, unspecified	0.011	0.989
O32.8 Maternal care for other malpresentation of foetus	0.011	0.989
O32.6 Maternal care for compound presentation	0.011	0.989
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.011	0.989
O32.4 Maternal care for high head at term	0.011	0.989
O32.3 Maternal care for face, brow and chin presentation	0.011	0.989
O32.2 Maternal care for transverse and oblique lie	0.011	0.989
O32.0 Maternal care for unstable lie	0.011	0.989
O46.8 Other antepartum haemorrhage	0.011	0.989
O46.0 Antepartum haemorrhage with coagulation defect	0.011	0.989
Y40 Systemic antibiotics	0.011	0.989
I70-I79 Diseases of arteries, arterioles and capillaries	0.011	0.989
F99-F99 Unspecified mental disorder	0.011	0.989
Chapter XVI Certain conditions originating in the perinatal period	0.011	0.989
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.011	0.989
O03 Spontaneous abortion	0.011	0.989
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.011	0.989
F70-F79 Mental retardation	0.011	0.989
Chapter XXII Codes for special purposes	0.011	0.989
T79-T79 Certain early complications of trauma	0.011	0.989
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.011	0.989
S70-S79 Injuries to the hip and thigh	0.010	0.989
N18.0 End-stage renal disease	0.011	0.989
O42.2 Premature rupture of membranes, labour delayed by therapy	0.010	0.989
T66-T78 Other and unspecified effects of external causes	0.010	0.989
E70-E90 Metabolic disorders	0.010	0.989
W25 Contact with sharp glass	0.010	0.990
O20.0 Threatened abortion	0.010	0.990
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.010	0.990
S05 Injury of eye and orbit	0.010	0.990
D69 Purpura and other haemorrhagic conditions	0.010	0.990
D10-D36 Benign neoplasms	0.010	0.990
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.010	0.990
S01.8 Open wound of other parts of head	0.010	0.990
O32.1 Maternal care for breech presentation	0.010	0.990
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.010	0.990
Y44 Agents primarily affecting blood constituents	0.010	0.990
V18 Pedal cyclist injured in noncollision transport accident	0.010	0.990
C50-C50 Malignant neoplasm of breast	0.010	0.990
D67 Hereditary factor IX deficiency	0.010	0.990
D66 Hereditary factor VIII deficiency	0.010	0.990
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.010	0.990
I12 Hypertensive renal disease	0.010	0.990
O46.9 Antepartum haemorrhage, unspecified	0.010	0.990
T92 Sequelae of injuries of upper limb	0.010	0.990
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.010	0.990
N18.5 Chronic kidney disease, stage 5	0.010	0.990
X50.4 Street and highway	0.010	0.990
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.010	0.990
D73 Diseases of spleen	0.010	0.990
Y86 Sequelae of other accidents	0.010	0.990
S40-S49 Injuries to the shoulder and upper arm	0.010	0.990
D68.2 Hereditary deficiency of other clotting factors	0.010	0.990
F41.9 Anxiety disorder, unspecified	0.010	0.990
E50-E64 Other nutritional deficiencies	0.010	0.990
Y60-Y69 Misadventures to patients during surgical and medical care	0.010	0.990
D75 Other diseases of blood and blood-forming organs	0.010	0.990
F48 Other neurotic disorders	0.010	0.990
F44 Dissociative [conversion] disorders	0.010	0.990
F42 Obsessive-compulsive disorder	0.010	0.990
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.010	0.990
S09 Other and unspecified injuries of head	0.010	0.990
D60-D64 Aplastic and other anaemias	0.010	0.990
W00-W19 Falls	0.010	0.990
O04.9 Complete or unspecified, without complication	0.010	0.990
T33-T35 Frostbite	0.010	0.990
T26-T28 Burns and corrosions confined to eye and internal organs	0.010	0.990
T20-T25 Burns and corrosions of external body surface, specified by site	0.010	0.990
T00-T07 Injuries involving multiple body regions	0.010	0.990
S10-S19 Injuries to the neck	0.010	0.990
Y51 Drugs primarily affecting the autonomic nervous system	0.010	0.990
I71 Aortic aneurysm and dissection	0.010	0.990
F40.2 Specific (isolated) phobias	0.010	0.990
H93.1 Tinnitus	0.010	0.990
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.010	0.990
F32 Depressive episode	0.010	0.990
S60-S69 Injuries to the wrist and hand	0.010	0.990
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.010	0.990
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.010	0.990
D12.6 Colon, unspecified	0.010	0.990
Y59 Other and unspecified vaccines and biological substances	0.010	0.990
Y58 Bacterial vaccines	0.010	0.990
Y57 Other and unspecified drugs and medicaments	0.010	0.990
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.010	0.990
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.010	0.990
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.010	0.990
Y53 Agents primarily affecting the gastro-intestinal system	0.010	0.990
Y52 Agents primarily affecting the cardiovascular system	0.010	0.990
Y50 Central nervous system stimulants, not elsewhere classified	0.010	0.990
Y48 Anaesthetics and therapeutic gases	0.010	0.990
Y47 Sedatives, hypnotics and antianxiety drugs	0.010	0.990
Y46 Antiepileptics and anti-Parkinsonism drugs	0.010	0.990
Y41 Other systemic anti-infectives and antiparasitics	0.010	0.990
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.010	0.990
C64-C68 Malignant neoplasms of urinary tract	0.010	0.990
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.010	0.990
D72.8 Other specified disorders of white blood cells	0.010	0.990
F10.4 Withdrawal state with delirium	0.010	0.990
T90 Sequelae of injuries of head	0.010	0.990
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.010	0.990
T15-T19 Effects of foreign body entering through natural orifice	0.010	0.990
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.010	0.990
W21.9 Unspecified place	0.010	0.990
F45 Somatoform disorders	0.010	0.990
C50 Malignant neoplasm of breast	0.010	0.990
F80 Specific developmental disorders of speech and language	0.010	0.990
Q50-Q56 Congenital malformations of genital organs	0.010	0.990
S00 Superficial injury of head	0.010	0.990
T14 Injury of unspecified body region	0.010	0.990
S06 Intracranial injury	0.010	0.990
S92 Fracture of foot, except ankle	0.010	0.990
W49 Exposure to other and unspecified inanimate mechanical forces	0.009	0.990
W46 Contact with hypodermic needle	0.009	0.990
W45 Foreign body or object entering through skin	0.009	0.990
W44 Foreign body entering into or through eye or natural orifice	0.009	0.990
W43 Exposure to vibration	0.009	0.990
W42 Exposure to noise	0.009	0.990
W41 Exposure to high-pressure jet	0.009	0.990
W40 Explosion of other materials	0.009	0.990
W39 Discharge of firework	0.009	0.990
W38 Explosion and rupture of other specified pressurised devices	0.009	0.990
W37 Explosion and rupture of pressurised tyre, pipe or hose	0.009	0.990
W36 Explosion and rupture of gas cylinder	0.009	0.990

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations