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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77837545
log Bayes Factor = 13.4569
Chromosome 5   position 35,622,892  (GRCh37) Explore rs77837545 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
M23 Internal derangement of knee
0.993 0.007 0.000
H30-H36 Disorders of choroid and retina
0.992 0.008 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.990 0.010 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.989 0.011 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.986 0.014 0.000
E10-E14 Diabetes mellitus
0.983 0.017 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.983 0.017 0.000
A30-A49 Other bacterial diseases
0.983 0.017 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.983 0.017 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.975 0.025 0.000
H36 Retinal disorders in diseases classified elsewhere
0.969 0.031 0.000
E20-E35 Disorders of other endocrine glands
0.967 0.033 0.000
M25 Other joint disorders, not elsewhere classified
0.967 0.033 0.000
T81 Complications of procedures, not elsewhere classified
0.967 0.033 0.000
Chapter IX Diseases of the circulatory system
0.967 0.033 0.000
A41 Other septicaemia
0.966 0.034 0.000
I30-I52 Other forms of heart disease
0.963 0.037 0.000
B95-B98 Bacterial, viral and other infectious agents
0.963 0.037 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.962 0.038 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.961 0.039 0.000
E11 Non-insulin-dependent diabetes mellitus
0.961 0.039 0.000
R50-R69 General symptoms and signs
0.959 0.041 0.000
O80-O84 Delivery
0.955 0.045 0.000
H36.0 Diabetic retinopathy
0.954 0.046 0.000
I50 Heart failure
0.954 0.046 0.000
R55 Syncope and collapse
0.953 0.047 0.000
E11.3 With ophthalmic complications
0.949 0.051 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.948 0.052 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.947 0.053 0.000
R20 Disturbances of skin sensation
0.947 0.053 0.000
E10 Insulin-dependent diabetes mellitus
0.946 0.054 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.936 0.064 0.000
Chapter VI Diseases of the nervous system
0.936 0.064 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.936 0.064 0.000
O42 Premature rupture of membranes
0.932 0.068 0.000
H35 Other retinal disorders
0.930 0.070 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.928 0.072 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.924 0.076 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.923 0.077 0.000
M50-M54 Other dorsopathies
0.921 0.079 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.920 0.080 0.000
I51 Complications and ill-defined descriptions of heart disease
0.918 0.082 0.000
O80 Single spontaneous delivery
0.918 0.082 0.000
M23.3 Other meniscus derangements
0.916 0.084 0.000
I50.1 Left ventricular failure
0.914 0.086 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.907 0.093 0.000
M25.4 Effusion of joint
0.906 0.094 0.000
E10.9 Without complications
0.905 0.095 0.000
G90-G99 Other disorders of the nervous system
0.904 0.096 0.000
I50.9 Heart failure, unspecified
0.896 0.104 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.896 0.104 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.894 0.106 0.000
O80.0 Spontaneous vertex delivery
0.890 0.110 0.000
M24 Other specific joint derangements
0.890 0.110 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.890 0.110 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.889 0.111 0.000
I42 Cardiomyopathy
0.888 0.112 0.000
A41.9 Septicaemia, unspecified
0.886 0.114 0.000
R30-R39 Symptoms and signs involving the urinary system
0.885 0.115 0.000
O47 False labour
0.885 0.115 0.000
H50 Other strabismus
0.881 0.119 0.000
O26.8 Other specified pregnancy-related conditions
0.879 0.121 0.000
H35.8 Other specified retinal disorders
0.879 0.121 0.000
A00-A09 Intestinal infectious diseases
0.875 0.125 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.875 0.125 0.000
A41.8 Other specified septicaemia
0.873 0.127 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.867 0.133 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.866 0.134 0.000
R54 Senility
0.865 0.135 0.000
I51.7 Cardiomegaly
0.859 0.141 0.000
M25.46 Effusion of joint (Lower leg)
0.859 0.141 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.859 0.141 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.858 0.142 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.856 0.144 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.854 0.146 0.000
M34 Systemic sclerosis
0.853 0.147 0.000
M65-M68 Disorders of synovium and tendon
0.850 0.150 0.000
I34 Nonrheumatic mitral valve disorders
0.848 0.152 0.000
G20-G26 Extrapyramidal and movement disorders
0.844 0.156 0.000
H53-H54 Visual disturbances and blindness
0.842 0.158 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.842 0.158 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.840 0.160 0.000
D70 Agranulocytosis
0.838 0.162 0.000
O36 Maternal care for other known or suspected foetal problems
0.837 0.163 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.835 0.165 0.000
H50.1 Divergent concomitant strabismus
0.835 0.165 0.000
R25 Abnormal involuntary movements
0.832 0.168 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.831 0.169 0.000
G96 Other disorders of central nervous system
0.830 0.170 0.000
R30 Pain associated with micturition
0.828 0.172 0.000
M25.9 Joint disorder, unspecified
0.828 0.172 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.826 0.174 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.823 0.177 0.000
O48 Prolonged pregnancy
0.821 0.179 0.000
Chapter II Neoplasms
0.818 0.182 0.000
R50 Fever of unknown origin
0.816 0.184 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.816 0.184 0.000
M50 Cervical disk disorders
0.816 0.184 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.815 0.185 0.000
E11.6 With other specified complications
0.814 0.186 0.000
I27 Other pulmonary heart diseases
0.813 0.187 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.812 0.188 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.812 0.188 0.000
S00-S09 Injuries to the head
0.810 0.190 0.000
E21.0 Primary hyperparathyroidism
0.810 0.190 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.809 0.191 0.000
G93 Other disorders of brain
0.809 0.191 0.000
O42.9 Premature rupture of membranes, unspecified
0.808 0.192 0.000
R35 Polyuria
0.808 0.192 0.000
R57 Shock, not elsewhere classified
0.807 0.193 0.000
S20-S29 Injuries to the thorax
0.807 0.193 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.806 0.194 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.804 0.196 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.803 0.197 0.000
M24.1 Other articular cartilage disorders
0.802 0.197 0.000
Q80-Q89 Other congenital malformations
0.800 0.200 0.000
R69 Unknown and unspecified causes of morbidity
0.800 0.200 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.798 0.202 0.000
R20.2 Paraesthesia of skin
0.797 0.203 0.000
E10.3 With ophthalmic complications
0.796 0.204 0.000
R26 Abnormalities of gait and mobility
0.795 0.205 0.000
H10-H13 Disorders of conjunctiva
0.792 0.208 0.000
E23 Hypofunction and other disorders of pituitary gland
0.792 0.208 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.791 0.209 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.791 0.209 0.000
E34 Other endocrine disorders
0.789 0.211 0.000
A49 Bacterial infection of unspecified site
0.789 0.211 0.000
Chapter V Mental and behavioural disorders
0.787 0.213 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.785 0.215 0.000
Q50-Q56 Congenital malformations of genital organs
0.785 0.215 0.000
R30.0 Dysuria
0.785 0.215 0.000
S09 Other and unspecified injuries of head
0.782 0.218 0.000
Q18 Other congenital malformations of face and neck
0.782 0.218 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.782 0.218 0.000
H55-H59 Other disorders of eye and adnexa
0.781 0.218 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.781 0.219 0.000
B25-B34 Other viral diseases
0.781 0.219 0.000
I27.0 Primary pulmonary hypertension
0.778 0.222 0.000
I36 Nonrheumatic tricuspid valve disorders
0.777 0.223 0.000
B15-B19 Viral hepatitis
0.774 0.226 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.773 0.227 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.773 0.227 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.772 0.228 0.000
M50.2 Other cervical disk displacement
0.769 0.231 0.000
O44 Placenta praevia
0.767 0.233 0.000
R32 Unspecified urinary incontinence
0.767 0.233 0.000
H33 Retinal detachments and breaks
0.766 0.234 0.000
M65 Synovitis and tenosynovitis
0.765 0.235 0.000
O00-O08 Pregnancy with abortive outcome
0.765 0.235 0.000
S90-S99 Injuries to the ankle and foot
0.764 0.236 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.764 0.236 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.764 0.236 0.000
I34.0 Mitral (valve) insufficiency
0.763 0.237 0.000
S09.9 Unspecified injury of head
0.763 0.237 0.000
O47.9 False labour, unspecified
0.763 0.237 0.000
M25.8 Other specified joint disorders
0.762 0.238 0.000
M00-M03 Infectious arthropathies
0.762 0.238 0.000
Chapter XXII Codes for special purposes
0.762 0.238 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.761 0.239 0.000
R60 Oedema, not elsewhere classified
0.760 0.240 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.758 0.242 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.757 0.243 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.757 0.243 0.000
M51 Other intervertebral disk disorders
0.756 0.244 0.000
R21 Rash and other nonspecific skin eruption
0.755 0.245 0.000
E22 Hyperfunction of pituitary gland
0.753 0.247 0.000
I42.2 Other hypertrophic cardiomyopathy
0.751 0.249 0.000
M91-M94 Chondropathies
0.751 0.249 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.750 0.250 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.750 0.250 0.000
S50-S59 Injuries to the elbow and forearm
0.749 0.251 0.000
G96.0 Cerebrospinal fluid leak
0.747 0.253 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.747 0.253 0.000
E11.2 With renal complications
0.747 0.253 0.000
E24 Cushing's syndrome
0.746 0.253 0.000
I42.9 Cardiomyopathy, unspecified
0.746 0.254 0.000
H53 Visual disturbances
0.746 0.254 0.000
E21.3 Hyperparathyroidism, unspecified
0.745 0.255 0.000
M21 Other acquired deformities of limbs
0.744 0.256 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.744 0.256 0.000
I51.6 Cardiovascular disease, unspecified
0.743 0.257 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.743 0.257 0.000
M25.0 Haemarthrosis
0.743 0.257 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.741 0.258 0.000
S10-S19 Injuries to the neck
0.740 0.260 0.000
E11.5 With peripheral circulatory complications
0.739 0.261 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.739 0.261 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.739 0.261 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.738 0.261 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.737 0.263 0.000
R50.0 Fever with chills
0.737 0.263 0.000
G25 Other extrapyramidal and movement disorders
0.737 0.263 0.000
T79-T79 Certain early complications of trauma
0.734 0.265 0.000
M23.8 Other internal derangements of knee
0.734 0.266 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.734 0.266 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.733 0.267 0.000
H35.6 Retinal haemorrhage
0.732 0.268 0.000
M23.5 Chronic instability of knee
0.731 0.269 0.000
M05-M14 Inflammatory polyarthropathies
0.731 0.269 0.000
D72 Other disorders of white blood cells
0.730 0.270 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.728 0.272 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.728 0.272 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.728 0.272 0.000
M25.96 Joint disorder, unspecified (Lower leg)
0.728 0.272 0.000
G70-G73 Diseases of myoneural junction and muscle
0.727 0.273 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.727 0.273 0.000
D80-D89 Certain disorders involving the immune mechanism
0.726 0.274 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.725 0.275 0.000
H50.9 Strabismus, unspecified
0.724 0.276 0.000
I30 Acute pericarditis
0.724 0.276 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.723 0.277 0.000
I50.0 Congestive heart failure
0.722 0.278 0.000
M15-M19 Arthrosis
0.722 0.278 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.720 0.280 0.000
E10.5 With peripheral circulatory complications
0.719 0.281 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.718 0.282 0.000
Q60-Q64 Congenital malformations of the urinary system
0.717 0.283 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.717 0.283 0.000
E28 Ovarian dysfunction
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.716 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.283 0.000
B65-B83 Helminthiases
0.716 0.283 0.000
B50-B64 Protozoal diseases
0.716 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.283 0.000
A75-A79 Rickettsioses
0.716 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.283 0.000
A65-A69 Other spirochaetal diseases
0.716 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.283 0.000
A15-A19 Tuberculosis
0.716 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
M32 Systemic lupus erythematosus
0.716 0.284 0.000
M30 Polyarteritis nodosa and related conditions
0.716 0.284 0.000
T87 Complications peculiar to reattachment and amputation
0.716 0.284 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.715 0.285 0.000
M25.3 Other instability of joint
0.715 0.285 0.000
M23.4 Loose body in knee
0.715 0.285 0.000
R23 Other skin changes
0.714 0.286 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.713 0.287 0.000
M23.9 Internal derangement of knee, unspecified
0.712 0.288 0.000
M23.1 Discoid meniscus (congenital)
0.712 0.288 0.000
M23.0 Cystic meniscus
0.712 0.288 0.000
C51-C58 Malignant neoplasms of female genital organs
0.712 0.288 0.000
I51.8 Other ill-defined heart diseases
0.712 0.288 0.000
M54 Dorsalgia
0.712 0.288 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.712 0.288 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.711 0.289 0.000
H31 Other disorders of choroid
0.711 0.289 0.000
H30 Chorioretinal inflammation
0.711 0.289 0.000
O81 Single delivery by forceps and vacuum extractor
0.711 0.289 0.000
E40-E46 Malnutrition
0.710 0.290 0.000
O20 Haemorrhage in early pregnancy
0.710 0.290 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.709 0.290 0.000
I51.4 Myocarditis, unspecified
0.709 0.290 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.709 0.291 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.708 0.292 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.708 0.292 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.708 0.292 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.707 0.293 0.000
O45 Premature separation of placenta [abruptio placentae]
0.707 0.293 0.000
O43 Placental disorders
0.707 0.293 0.000
O33 Maternal care for known or suspected disproportion
0.707 0.293 0.000
O31 Complications specific to multiple gestation
0.707 0.293 0.000
O40 Polyhydramnios
0.707 0.293 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.707 0.293 0.000
E13 Other specified diabetes mellitus
0.705 0.295 0.000
E12 Malnutrition-related diabetes mellitus
0.705 0.295 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.705 0.295 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.705 0.295 0.000
Q35-Q37 Cleft lip and cleft palate
0.705 0.295 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.705 0.295 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.705 0.295 0.000
A48 Other bacterial diseases, not elsewhere classified
0.705 0.295 0.000
A44 Bartonellosis
0.705 0.295 0.000
A43 Nocardiosis
0.705 0.295 0.000
A42 Actinomycosis
0.705 0.295 0.000
A40 Streptococcal septicaemia
0.705 0.295 0.000
A39 Meningococcal infection
0.705 0.295 0.000
A37 Whooping cough
0.705 0.295 0.000
A36 Diphtheria
0.705 0.295 0.000
A32 Listeriosis
0.705 0.295 0.000
A31 Infection due to other mycobacteria
0.705 0.295 0.000
A30 Leprosy [Hansen's disease]
0.705 0.295 0.000
A46 Erysipelas
0.705 0.295 0.000
A38 Scarlet fever
0.705 0.295 0.000
A35 Other tetanus
0.705 0.295 0.000
A34 Obstetrical tetanus
0.705 0.295 0.000
A33 Tetanus neonatorum
0.705 0.295 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.705 0.295 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.705 0.295 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.705 0.295 0.000
Q27 Other congenital malformations of peripheral vascular system
0.704 0.296 0.000
E29 Testicular dysfunction
0.704 0.296 0.000
H35.5 Hereditary retinal dystrophy
0.704 0.296 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.704 0.296 0.000
M86-M90 Other osteopathies
0.701 0.299 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.700 0.300 0.000
D75 Other diseases of blood and blood-forming organs
0.700 0.300 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.699 0.301 0.000
M34.9 Systemic sclerosis, unspecified
0.698 0.302 0.000
R57.2 Septic shock
0.697 0.302 0.000
R26.0 Ataxic gait
0.697 0.303 0.000
O82 Single delivery by Caesarean section
0.695 0.305 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.695 0.305 0.000
Q23 Congenital malformations of aortic and mitral valves
0.695 0.305 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.694 0.306 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.694 0.306 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.693 0.306 0.000
E32 Diseases of thymus
0.693 0.306 0.000
E31 Polyglandular dysfunction
0.693 0.306 0.000
E30 Disorders of puberty, not elsewhere classified
0.693 0.306 0.000
E27 Other disorders of adrenal gland
0.693 0.306 0.000
E26 Hyperaldosteronism
0.693 0.306 0.000
E25 Adrenogenital disorders
0.693 0.306 0.000
E20 Hypoparathyroidism
0.693 0.306 0.000
M25.2 Flail joint
0.693 0.307 0.000
M25.1 Fistula of joint
0.693 0.307 0.000
T81.9 Unspecified complication of procedure
0.693 0.307 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.693 0.307 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.693 0.307 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.693 0.307 0.000
I00-I02 Acute rheumatic fever
0.693 0.307 0.000
A41.4 Septicaemia due to anaerobes
0.692 0.307 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.692 0.307 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.692 0.307 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.692 0.307 0.000
M34.1 CR(E)ST syndrome
0.692 0.308 0.000
H34 Retinal vascular occlusions
0.691 0.309 0.000
I52 Other heart disorders in diseases classified elsewhere
0.691 0.309 0.000
I48 Atrial fibrillation and flutter
0.691 0.309 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.691 0.309 0.000
I41 Myocarditis in diseases classified elsewhere
0.691 0.309 0.000
I40 Acute myocarditis
0.691 0.309 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.691 0.309 0.000
I37 Pulmonary valve disorders
0.691 0.309 0.000
I32 Pericarditis in diseases classified elsewhere
0.691 0.309 0.000
O47.0 False labour before 37 completed weeks of gestation
0.690 0.310 0.000
G93.3 Postviral fatigue syndrome
0.690 0.310 0.000
T88.5 Other complications of anaesthesia
0.690 0.310 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.690 0.310 0.000
E11.8 With unspecified complications
0.689 0.311 0.000
E11.7 With multiple complications
0.689 0.311 0.000
E11.1 With ketoacidosis
0.689 0.311 0.000
E11.0 With coma
0.689 0.311 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.688 0.312 0.000
R62 Lack of expected normal physiological development
0.688 0.312 0.000
R64 Cachexia
0.688 0.312 0.000
R58 Haemorrhage, not elsewhere classified
0.688 0.312 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.688 0.312 0.000
O36.6 Maternal care for excessive foetal growth
0.688 0.312 0.000
O36.9 Maternal care for foetal problem, unspecified
0.688 0.312 0.000
A80-A89 Viral infections of the central nervous system
0.687 0.313 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.687 0.313 0.000
T86 Failure and rejection of transplanted organs and tissues
0.686 0.314 0.000
O41 Other disorders of amniotic fluid and membranes
0.685 0.315 0.000
O84 Multiple delivery
0.684 0.315 0.000
O83 Other assisted single delivery
0.684 0.315 0.000
H43-H45 Disorders of vitreous body and globe
0.683 0.317 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.683 0.317 0.000
Q00-Q07 Congenital malformations of the nervous system
0.682 0.317 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.682 0.318 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.681 0.318 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.680 0.320 0.000
Q18.0 Sinus, fistula and cyst of branchial cleft
0.679 0.321 0.000
O29 Complications of anaesthesia during pregnancy
0.679 0.321 0.000
O28 Abnormal findings on antenatal screening of mother
0.679 0.321 0.000
O23 Infections of genito-urinary tract in pregnancy
0.679 0.321 0.000
O22 Venous complications in pregnancy
0.679 0.321 0.000
O21 Excessive vomiting in pregnancy
0.679 0.321 0.000
O25 Malnutrition in pregnancy
0.679 0.321 0.000
M40-M43 Deforming dorsopathies
0.679 0.321 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.679 0.321 0.000
R20.3 Hyperaesthesia
0.679 0.321 0.000
R20.1 Hypoaesthesia of skin
0.679 0.321 0.000
R20.0 Anaesthesia of skin
0.679 0.321 0.000
E10.8 With unspecified complications
0.678 0.322 0.000
E10.7 With multiple complications
0.678 0.322 0.000
E10.6 With other specified complications
0.678 0.322 0.000
E10.2 With renal complications
0.678 0.322 0.000
E10.0 With coma
0.678 0.322 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.678 0.322 0.000
M31 Other necrotising vasculopathies
0.678 0.322 0.000
I71 Aortic aneurysm and dissection
0.676 0.324 0.000
G20 Parkinson's disease
0.674 0.326 0.000
I05-I09 Chronic rheumatic heart diseases
0.673 0.327 0.000
H35.0 Background retinopathy and retinal vascular changes
0.672 0.328 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.672 0.328 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.671 0.329 0.000
R25.3 Fasciculation
0.671 0.329 0.000
M25.47 Effusion of joint (Ankle and foot)
0.670 0.330 0.000
Q85 Phakomatoses, not elsewhere classified
0.669 0.331 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.668 0.332 0.000
O36.5 Maternal care for poor foetal growth
0.667 0.333 0.000
Q28 Other congenital malformations of circulatory system
0.667 0.333 0.000
H35.9 Retinal disorder, unspecified
0.667 0.333 0.000
H35.7 Separation of retinal layers
0.667 0.333 0.000
H35.2 Other proliferative retinopathy
0.667 0.333 0.000
H35.1 Retinopathy of prematurity
0.667 0.333 0.000
O80.9 Single spontaneous delivery, unspecified
0.667 0.333 0.000
H53.0 Amblyopia ex anopsia
0.667 0.333 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.666 0.334 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.666 0.334 0.000
I33 Acute and subacute endocarditis
0.665 0.335 0.000
D73 Diseases of spleen
0.665 0.335 0.000
Q38.7 Pharyngeal pouch
0.664 0.336 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.664 0.336 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.664 0.336 0.000
S40-S49 Injuries to the shoulder and upper arm
0.662 0.337 0.000
H51 Other disorders of binocular movement
0.662 0.337 0.000
H49 Paralytic strabismus
0.662 0.337 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.662 0.338 0.000
E34.0 Carcinoid syndrome
0.662 0.338 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.661 0.339 0.000
O24 Diabetes mellitus in pregnancy
0.661 0.339 0.000
H35.3 Degeneration of macula and posterior pole
0.660 0.340 0.000
S70-S79 Injuries to the hip and thigh
0.660 0.340 0.000
D55-D59 Haemolytic anaemias
0.659 0.340 0.000
I51.5 Myocardial degeneration
0.658 0.341 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.658 0.341 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.658 0.341 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.658 0.341 0.000
I51.0 Cardiac septal defect, acquired
0.658 0.341 0.000
H53.9 Visual disturbance, unspecified
0.659 0.341 0.000
E10.4 With neurological complications
0.658 0.342 0.000
M16 Coxarthrosis [arthrosis of hip]
0.658 0.342 0.000
O80.8 Other single spontaneous delivery
0.658 0.342 0.000
O80.1 Spontaneous breech delivery
0.658 0.342 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.657 0.343 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.657 0.343 0.000
M23.37 Other meniscus derangements-Capsular lig
0.657 0.343 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.657 0.343 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.657 0.343 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.657 0.343 0.000
I72 Other aneurysm
0.657 0.343 0.000
C80 Malignant neoplasm without specification of site
0.655 0.345 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.654 0.346 0.000
Q18.1 Preauricular sinus and cyst
0.654 0.346 0.000
G93.8 Other specified disorders of brain
0.653 0.346 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.652 0.348 0.000
E11.4 With neurological complications
0.652 0.348 0.000
H33.1 Retinoschisis and retinal cysts
0.652 0.348 0.000
F03 Unspecified dementia
0.652 0.348 0.000
G93.4 Encephalopathy, unspecified
0.652 0.348 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.651 0.349 0.000
I44 Atrioventricular and left bundle-branch block
0.650 0.350 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.650 0.350 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.650 0.350 0.000
O26.5 Maternal hypotension syndrome
0.650 0.350 0.000
O26.4 Herpes gestationis
0.650 0.350 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.650 0.350 0.000
O26.2 Pregnancy care of habitual aborter
0.650 0.350 0.000
O26.1 Low weight gain in pregnancy
0.650 0.350 0.000
O26.0 Excessive weight gain in pregnancy
0.650 0.350 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.650 0.350 0.000
Q21 Congenital malformations of cardiac septa
0.650 0.350 0.000
E23.0 Hypopituitarism
0.650 0.350 0.000
M25.49 Effusion of joint (Site unspecified)
0.650 0.350 0.000
M25.48 Effusion of joint (Other)
0.650 0.350 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.650 0.350 0.000
M25.44 Effusion of joint (Hand)
0.650 0.350 0.000
M25.43 Effusion of joint (Forearm)
0.650 0.350 0.000
M25.42 Effusion of joint (Upper arm)
0.650 0.350 0.000
M25.41 Effusion of joint (Shoulder region)
0.650 0.350 0.000
M25.40 Effusion of joint (Multiple sites)
0.650 0.350 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.649 0.351 0.000
I45 Other conduction disorders
0.649 0.351 0.000
R50.8 Other specified fever
0.648 0.352 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.648 0.352 0.000
G90 Disorders of autonomic nervous system
0.648 0.352 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.648 0.352 0.000
G92 Toxic encephalopathy
0.648 0.352 0.000
O26.9 Pregnancy-related condition, unspecified
0.648 0.352 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.646 0.354 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.646 0.354 0.000
I42.0 Dilated cardiomyopathy
0.645 0.354 0.000
M45-M49 Spondylopathies
0.645 0.355 0.000
H11 Other disorders of conjunctiva
0.644 0.356 0.000
M65.3 Trigger finger
0.644 0.356 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.643 0.356 0.000
M53 Other dorsopathies, not elsewhere classified
0.643 0.357 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.643 0.357 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.642 0.358 0.000
E21.4 Other specified disorders of parathyroid gland
0.642 0.358 0.000
E21.2 Other hyperparathyroidism
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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