TreeWAS – Variant ID: rs77840280

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
Chapter II Neoplasms	1.000	0.000	0.000
C79 Secondary malignant neoplasm of other sites	1.000	0.000	0.000
Chapter I Certain infectious and parasitic diseases	0.999	0.001	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.999	0.001	0.000
A30-A49 Other bacterial diseases	0.998	0.002	0.000
Chapter XX External causes of morbidity and mortality	0.998	0.002	0.000
Chapter X Diseases of the respiratory system	0.998	0.002	0.000
J40-J47 Chronic lower respiratory diseases	0.997	0.003	0.000
A41 Other septicaemia	0.997	0.003	0.000
Chapter VI Diseases of the nervous system	0.997	0.003	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.996	0.004	0.000
A41.9 Septicaemia, unspecified	0.996	0.004	0.000
J44 Other chronic obstructive pulmonary disease	0.996	0.004	0.000
G90-G99 Other disorders of the nervous system	0.992	0.008	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.989	0.011	0.000
C78.0 Secondary malignant neoplasm of lung	0.987	0.013	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.976	0.024	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.972	0.028	0.000
G93 Other disorders of brain	0.970	0.030	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.966	0.034	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.960	0.040	0.000
Y95 Nosocomial condition	0.958	0.042	0.000
J43 Emphysema	0.949	0.051	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.948	0.052	0.000
Chapter VIII Diseases of the ear and mastoid process	0.939	0.061	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.937	0.063	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.934	0.066	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.934	0.066	0.000
C78.2 Secondary malignant neoplasm of pleura	0.930	0.070	0.000
C45 Mesothelioma	0.928	0.072	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.923	0.077	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.922	0.078	0.000
J43.9 Emphysema, unspecified	0.914	0.086	0.000
A41.5 Septicaemia due to other Gram-negative organisms	0.907	0.093	0.000
G93.3 Postviral fatigue syndrome	0.895	0.105	0.000
S80-S89 Injuries to the knee and lower leg	0.895	0.105	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.894	0.106	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.889	0.111	0.000
J42 Unspecified chronic bronchitis	0.884	0.116	0.000
H90-H95 Other disorders of ear	0.883	0.117	0.000
Q60-Q64 Congenital malformations of the urinary system	0.882	0.118	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.880	0.120	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.872	0.128	0.000
G40-G47 Episodic and paroxysmal disorders	0.872	0.128	0.000
C64-C68 Malignant neoplasms of urinary tract	0.872	0.128	0.000
C45.0 Mesothelioma of pleura	0.868	0.132	0.000
C71 Malignant neoplasm of brain	0.866	0.134	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.866	0.134	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.858	0.142	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.858	0.142	0.000
A46 Erysipelas	0.851	0.149	0.000
Chapter IX Diseases of the circulatory system	0.850	0.150	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.850	0.150	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.845	0.155	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.842	0.158	0.000
B35-B49 Mycoses	0.842	0.158	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.841	0.159	0.000
S60-S69 Injuries to the wrist and hand	0.838	0.162	0.000
Q00-Q07 Congenital malformations of the nervous system	0.834	0.166	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.833	0.167	0.000
S10-S19 Injuries to the neck	0.831	0.169	0.000
D70 Agranulocytosis	0.831	0.169	0.000
Chapter V Mental and behavioural disorders	0.831	0.169	0.000
H91 Other hearing loss	0.830	0.170	0.000
C79.2 Secondary malignant neoplasm of skin	0.828	0.172	0.000
X60-X84 Intentional self-harm	0.828	0.172	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.827	0.173	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.826	0.174	0.000
G40 Epilepsy	0.825	0.175	0.000
S82 Fracture of lower leg, including ankle	0.822	0.178	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.821	0.179	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.820	0.180	0.000
W00-W19 Falls	0.816	0.184	0.000
D68 Other coagulation defects	0.814	0.186	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.813	0.187	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.812	0.188	0.000
S80 Superficial injury of lower leg	0.810	0.190	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.804	0.196	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.804	0.196	0.000
Q61 Cystic kidney disease	0.801	0.199	0.000
J95-J99 Other diseases of the respiratory system	0.800	0.200	0.000
Y84.6 Urinary catheterisation	0.799	0.201	0.000
G82 Paraplegia and tetraplegia	0.790	0.210	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.790	0.210	0.000
J09-J18 Influenza and pneumonia	0.788	0.212	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.788	0.212	0.000
D00-D09 In situ neoplasms	0.786	0.214	0.000
G70-G73 Diseases of myoneural junction and muscle	0.785	0.215	0.000
C45.9 Mesothelioma, unspecified	0.785	0.215	0.000
Chapter XXII Codes for special purposes	0.784	0.216	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.778	0.222	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.776	0.224	0.000
H91.9 Hearing loss, unspecified	0.775	0.225	0.000
G93.9 Disorder of brain, unspecified	0.775	0.225	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.774	0.226	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.772	0.228	0.000
X20-X29 Contact with venomous animals and plants	0.770	0.229	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.770	0.230	0.000
Chapter VII Diseases of the eye and adnexa	0.763	0.237	0.000
I71 Aortic aneurysm and dissection	0.761	0.239	0.000
C71.1 Frontal lobe	0.761	0.239	0.000
G90 Disorders of autonomic nervous system	0.760	0.240	0.000
F80-F89 Disorders of psychological development	0.759	0.241	0.000
D55-D59 Haemolytic anaemias	0.759	0.241	0.000
G96 Other disorders of central nervous system	0.758	0.242	0.000
G93.6 Cerebral oedema	0.758	0.242	0.000
G93.4 Encephalopathy, unspecified	0.758	0.242	0.000
C78.7 Secondary malignant neoplasm of liver	0.755	0.245	0.000
I05-I09 Chronic rheumatic heart diseases	0.754	0.246	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.752	0.248	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.751	0.249	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.750	0.250	0.000
G93.8 Other specified disorders of brain	0.749	0.251	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.748	0.252	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.748	0.252	0.000
C45.7 Mesothelioma of other sites	0.744	0.256	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.742	0.258	0.000
J40 Bronchitis, not specified as acute or chronic	0.742	0.258	0.000
G93.0 Cerebral cysts	0.740	0.260	0.000
T91 Sequelae of injuries of neck and trunk	0.740	0.260	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.739	0.261	0.000
Q50-Q56 Congenital malformations of genital organs	0.738	0.262	0.000
S82.1 Fracture of upper end of tibia	0.737	0.263	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.737	0.263	0.000
W20-W49 Exposure to inanimate mechanical forces	0.736	0.264	0.000
Q05 Spina bifida	0.735	0.265	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.735	0.265	0.000
C77.1 Intrathoracic lymph nodes	0.735	0.265	0.000
J84 Other interstitial pulmonary diseases	0.734	0.266	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.733	0.267	0.000
Y83.6 Removal of other organ (partial) (total)	0.733	0.267	0.000
V80-V89 Other land transport accidents	0.731	0.268	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.731	0.269	0.000
H93 Other disorders of ear, not elsewhere classified	0.731	0.269	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.730	0.270	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.730	0.270	0.000
A00-A09 Intestinal infectious diseases	0.728	0.272	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.727	0.273	0.000
I60-I69 Cerebrovascular diseases	0.725	0.275	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.722	0.278	0.000
S80.8 Other superficial injuries of lower leg	0.721	0.279	0.000
C71.9 Brain, unspecified	0.718	0.282	0.000
T90 Sequelae of injuries of head	0.717	0.283	0.000
D68.2 Hereditary deficiency of other clotting factors	0.717	0.283	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283	0.000
C79.6 Secondary malignant neoplasm of ovary	0.717	0.283	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.717	0.283	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.717	0.283	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.717	0.283	0.000
B99-B99 Other infectious diseases	0.716	0.283	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.716	0.283	0.000
B65-B83 Helminthiases	0.716	0.283	0.000
B50-B64 Protozoal diseases	0.716	0.283	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.716	0.283	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.716	0.283	0.000
A75-A79 Rickettsioses	0.716	0.283	0.000
A70-A74 Other diseases caused by chlamydiae	0.716	0.283	0.000
A65-A69 Other spirochaetal diseases	0.716	0.283	0.000
A20-A28 Certain zoonotic bacterial diseases	0.716	0.283	0.000
A15-A19 Tuberculosis	0.716	0.283	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.716	0.284	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.716	0.284	0.000
A48 Other bacterial diseases, not elsewhere classified	0.716	0.284	0.000
A44 Bartonellosis	0.716	0.284	0.000
A43 Nocardiosis	0.716	0.284	0.000
A42 Actinomycosis	0.716	0.284	0.000
A40 Streptococcal septicaemia	0.716	0.284	0.000
A39 Meningococcal infection	0.716	0.284	0.000
A37 Whooping cough	0.716	0.284	0.000
A36 Diphtheria	0.716	0.284	0.000
A32 Listeriosis	0.716	0.284	0.000
A31 Infection due to other mycobacteria	0.716	0.284	0.000
A30 Leprosy [Hansen's disease]	0.716	0.284	0.000
A38 Scarlet fever	0.716	0.284	0.000
A35 Other tetanus	0.716	0.284	0.000
A34 Obstetrical tetanus	0.716	0.284	0.000
A33 Tetanus neonatorum	0.716	0.284	0.000
Y35-Y36 Legal intervention and operations of war	0.716	0.284	0.000
Y10-Y34 Event of undetermined intent	0.716	0.284	0.000
Y00-Y09 Assault	0.716	0.284	0.000
X85-X99 Assault	0.716	0.284	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.716	0.284	0.000
X50-X57 Overexertion, travel and privation	0.716	0.284	0.000
X30-X39 Exposure to forces of nature	0.716	0.284	0.000
X10-X19 Contact with heat and hot substances	0.716	0.284	0.000
X00-X09 Exposure to smoke, fire and flames	0.716	0.284	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.716	0.284	0.000
W75-W84 Other accidental threats to breathing	0.716	0.284	0.000
W65-W74 Accidental drowning and submersion	0.716	0.284	0.000
W50-W64 Exposure to animate mechanical forces	0.716	0.284	0.000
V98-V99 Other and unspecified transport accidents	0.716	0.284	0.000
V95-V97 Air and space transport accidents	0.716	0.284	0.000
V90-V94 Water transport accidents	0.716	0.284	0.000
V70-V79 Bus occupant injured in transport accident	0.716	0.284	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.716	0.284	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.716	0.284	0.000
V40-V49 Car occupant injured in transport accident	0.716	0.284	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.716	0.284	0.000
V01-V09 Pedestrian injured in transport accident	0.716	0.284	0.000
J41 Simple and mucopurulent chronic bronchitis	0.715	0.285	0.000
A41.4 Septicaemia due to anaerobes	0.715	0.285	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.715	0.285	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.715	0.285	0.000
S68 Traumatic amputation of wrist and hand	0.714	0.286	0.000
G41 Status epilepticus	0.714	0.286	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.714	0.286	0.000
Q80-Q89 Other congenital malformations	0.714	0.286	0.000
C71.2 Temporal lobe	0.713	0.287	0.000
C77.5 Intrapelvic lymph nodes	0.712	0.288	0.000
D72 Other disorders of white blood cells	0.712	0.288	0.000
A80-A89 Viral infections of the central nervous system	0.712	0.288	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.711	0.288	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.711	0.288	0.000
G92 Toxic encephalopathy	0.711	0.288	0.000
G30-G32 Other degenerative diseases of the nervous system	0.709	0.291	0.000
F81 Specific developmental disorders of scholastic skills	0.709	0.291	0.000
J80 Adult respiratory distress syndrome	0.709	0.291	0.000
V10-V19 Pedal cyclist injured in transport accident	0.708	0.292	0.000
H80-H83 Diseases of inner ear	0.708	0.292	0.000
H65-H75 Diseases of middle ear and mastoid	0.708	0.292	0.000
G91 Hydrocephalus	0.707	0.293	0.000
G12 Spinal muscular atrophy and related syndromes	0.706	0.294	0.000
J90-J94 Other diseases of pleura	0.703	0.297	0.000
F60-F69 Disorders of adult personality and behaviour	0.703	0.297	0.000
G95 Other diseases of spinal cord	0.701	0.299	0.000
Q61.3 Polycystic kidney, unspecified	0.700	0.300	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.699	0.300	0.000
Y98 Lifestyle-related condition	0.699	0.300	0.000
Y97 Environmental-pollution-related condition	0.699	0.300	0.000
Y96 Work-related condition	0.699	0.300	0.000
I73 Other peripheral vascular diseases	0.698	0.302	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.697	0.303	0.000
Q35-Q37 Cleft lip and cleft palate	0.697	0.303	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.697	0.303	0.000
G93.7 Reye's syndrome	0.696	0.304	0.000
G93.5 Compression of brain	0.696	0.304	0.000
G93.2 Benign intracranial hypertension	0.696	0.304	0.000
C67 Malignant neoplasm of bladder	0.694	0.306	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.693	0.306	0.000
J46 Status asthmaticus	0.693	0.307	0.000
T33-T35 Frostbite	0.692	0.308	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.692	0.308	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.692	0.308	0.000
T00-T07 Injuries involving multiple body regions	0.692	0.308	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.692	0.308	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.692	0.308	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.691	0.309	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.688	0.312	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.688	0.312	0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.688	0.312	0.000
C46 Kaposi's sarcoma	0.688	0.312	0.000
T79-T79 Certain early complications of trauma	0.687	0.313	0.000
Y52 Agents primarily affecting the cardiovascular system	0.686	0.313	0.000
I77 Other disorders of arteries and arterioles	0.686	0.314	0.000
D68.0 Von Willebrand's disease	0.686	0.314	0.000
G40.8 Other epilepsy	0.686	0.314	0.000
S86 Injury of muscle and tendon at lower leg level	0.685	0.315	0.000
A41.8 Other specified septicaemia	0.685	0.315	0.000
G82.5 Tetraplegia, unspecified	0.685	0.315	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.683	0.317	0.000
J47 Bronchiectasis	0.683	0.317	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.682	0.318	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.682	0.318	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.682	0.318	0.000
S70-S79 Injuries to the hip and thigh	0.680	0.319	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.680	0.320	0.000
J43.8 Other emphysema	0.680	0.320	0.000
J43.2 Centrilobular emphysema	0.680	0.320	0.000
J43.1 Panlobular emphysema	0.680	0.320	0.000
J43.0 MacLeod's syndrome	0.680	0.320	0.000
S12 Fracture of neck	0.679	0.321	0.000
Q61.2 Polycystic kidney, adult type	0.677	0.323	0.000
S82.10 Fracture of upper end of tibia (closed)	0.677	0.323	0.000
C77.8 Lymph nodes of multiple regions	0.676	0.324	0.000
G82.2 Paraplegia, unspecified	0.675	0.325	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.674	0.326	0.000
D03 Melanoma in situ	0.674	0.326	0.000
C50-C50 Malignant neoplasm of breast	0.673	0.327	0.000
B02 Zoster [herpes zoster]	0.672	0.328	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.672	0.328	0.000
S20-S29 Injuries to the thorax	0.672	0.328	0.000
W06 Fall involving bed	0.672	0.328	0.000
S82.4 Fracture of fibula alone	0.671	0.328	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.671	0.329	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.670	0.330	0.000
B15-B19 Viral hepatitis	0.668	0.332	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.667	0.333	0.000
D66 Hereditary factor VIII deficiency	0.667	0.333	0.000
C45.2 Mesothelioma of pericardium	0.665	0.335	0.000
C45.1 Mesothelioma of peritoneum	0.665	0.335	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.665	0.335	0.000
Q05.9 Spina bifida, unspecified	0.665	0.335	0.000
H91.8 Other specified hearing loss	0.664	0.336	0.000
W18 Other fall on same level	0.663	0.337	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.662	0.338	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.662	0.338	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.662	0.338	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.661	0.339	0.000
C70 Malignant neoplasm of meninges	0.661	0.339	0.000
C69 Malignant neoplasm of eye and adnexa	0.661	0.339	0.000
A49 Bacterial infection of unspecified site	0.661	0.339	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.660	0.340	0.000
H60-H62 Diseases of external ear	0.659	0.341	0.000
S80.9 Superficial injury of lower leg, unspecified	0.659	0.341	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.658	0.341	0.001
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.657	0.343	0.000
T86 Failure and rejection of transplanted organs and tissues	0.656	0.344	0.000
Q63 Other congenital malformations of kidney	0.655	0.345	0.000
S82.0 Fracture of patella	0.655	0.345	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.654	0.346	0.000
J98 Other respiratory disorders	0.653	0.347	0.000
D73 Diseases of spleen	0.652	0.348	0.000
B49 Unspecified mycosis	0.651	0.349	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.651	0.349	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.651	0.349	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.650	0.350	0.000
G20-G26 Extrapyramidal and movement disorders	0.649	0.350	0.000
V20-V29 Motorcycle rider injured in transport accident	0.649	0.351	0.000
G44 Other headache syndromes	0.649	0.351	0.000
C80 Malignant neoplasm without specification of site	0.648	0.352	0.000
H90 Conductive and sensorineural hearing loss	0.648	0.352	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.647	0.353	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.647	0.353	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.646	0.354	0.000
T87 Complications peculiar to reattachment and amputation	0.646	0.354	0.000
I26 Pulmonary embolism	0.646	0.354	0.000
A63.0 Anogenital (venereal) warts	0.646	0.354	0.000
C66 Malignant neoplasm of ureter	0.645	0.355	0.000
B35 Dermatophytosis	0.644	0.356	0.000
I08 Multiple valve diseases	0.643	0.357	0.000
I73.9 Peripheral vascular disease, unspecified	0.643	0.357	0.000
B37 Candidiasis	0.642	0.358	0.000
G71 Primary disorders of muscles	0.642	0.358	0.000
S88 Traumatic amputation of lower leg	0.642	0.358	0.000
S87 Crushing injury of lower leg	0.642	0.358	0.000
S85 Injury of blood vessels at lower leg level	0.642	0.358	0.000
S84 Injury of nerves at lower leg level	0.642	0.358	0.000
J14 Pneumonia due to Haemophilus influenzae	0.642	0.358	0.000
D68.9 Coagulation defect, unspecified	0.641	0.358	0.000
I07 Rheumatic tricuspid valve diseases	0.641	0.359	0.000
G40.9 Epilepsy, unspecified	0.641	0.359	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.641	0.359	0.000
T93 Sequelae of injuries of lower limb	0.640	0.360	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.640	0.360	0.000
S19 Other and unspecified injuries of neck	0.639	0.361	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.639	0.361	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.639	0.361	0.000
B44 Aspergillosis	0.638	0.362	0.000
T66-T78 Other and unspecified effects of external causes	0.638	0.362	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.638	0.362	0.000
Y83.9 Surgical procedure, unspecified	0.637	0.363	0.000
J60-J70 Lung diseases due to external agents	0.636	0.364	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.636	0.364	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.633	0.367	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.633	0.367	0.000
S10 Superficial injury of neck	0.633	0.367	0.000
J91 Pleural effusion in conditions classified elsewhere	0.632	0.368	0.000
Q64 Other congenital malformations of urinary system	0.632	0.368	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.632	0.368	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.631	0.369	0.000
D68.5 Primary Thrombophilia	0.631	0.369	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.631	0.369	0.000
D74 Methaemoglobinaemia	0.631	0.369	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.631	0.369	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.631	0.369	0.000
I63 Cerebral infarction	0.631	0.369	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.630	0.370	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.629	0.371	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.629	0.371	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.628	0.372	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.628	0.372	0.000
B25-B34 Other viral diseases	0.627	0.372	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.626	0.374	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.625	0.374	0.000
S82.6 Fracture of lateral malleolus	0.625	0.375	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.625	0.375	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.625	0.375	0.000
C65 Malignant neoplasm of renal pelvis	0.625	0.375	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.625	0.375	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.625	0.375	0.000
C51-C58 Malignant neoplasms of female genital organs	0.624	0.376	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.623	0.377	0.000
Y43 Primarily systemic agents	0.622	0.378	0.000
H93.1 Tinnitus	0.622	0.378	0.000
C71.8 Overlapping lesion of brain	0.621	0.379	0.000
C71.7 Brain stem	0.621	0.379	0.000
C71.6 Cerebellum	0.621	0.379	0.000
C71.5 Cerebral ventricle	0.621	0.379	0.000
C71.4 Occipital lobe	0.621	0.379	0.000
C71.3 Parietal lobe	0.621	0.379	0.000
C71.0 Cerebrum, except lobes and ventricles	0.621	0.379	0.000
T98 Sequelae of other and unspecified effects of external causes	0.621	0.379	0.000
T95 Sequelae of burns, corrosions and frostbite	0.621	0.379	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.621	0.379	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.621	0.379	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.621	0.379	0.000
C77.2 Intra-abdominal lymph nodes	0.620	0.380	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.620	0.380	0.000
Y83.4 Other reconstructive surgery	0.620	0.380	0.000
G12.2 Motor neuron disease	0.618	0.382	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.617	0.383	0.000
I78 Diseases of capillaries	0.617	0.383	0.000
J11 Influenza, virus not identified	0.617	0.383	0.000
G80 Infantile cerebral palsy	0.616	0.383	0.000
B95-B98 Bacterial, viral and other infectious agents	0.616	0.384	0.000
D67 Hereditary factor IX deficiency	0.615	0.385	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.615	0.385	0.000
D80-D89 Certain disorders involving the immune mechanism	0.615	0.385	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.615	0.385	0.000
G82.1 Spastic paraplegia	0.615	0.385	0.000
T92 Sequelae of injuries of upper limb	0.615	0.385	0.000
S67 Crushing injury of wrist and hand	0.614	0.386	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.614	0.386	0.000
C60-C63 Malignant neoplasms of male genital organs	0.614	0.386	0.000
W08 Fall involving other furniture	0.614	0.386	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.613	0.387	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.612	0.387	0.000
B91 Sequelae of poliomyelitis	0.612	0.388	0.000
D07.5 Prostate	0.612	0.388	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.611	0.389	0.000
F60 Specific personality disorders	0.611	0.389	0.000
H46 Optic neuritis	0.611	0.389	0.000
S64 Injury of nerves at wrist and hand level	0.610	0.390	0.000
I00-I02 Acute rheumatic fever	0.610	0.390	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.609	0.391	0.000
C77.4 Inguinal and lower limb lymph nodes	0.609	0.391	0.000
X23 Contact with hornets, wasps and bees	0.607	0.393	0.000
Y57 Other and unspecified drugs and medicaments	0.607	0.393	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.607	0.393	0.000
D58 Other hereditary haemolytic anaemias	0.606	0.393	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.606	0.394	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.606	0.394	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.606	0.394	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.606	0.394	0.000
T83.2 Mechanical complication of graft of urinary organ	0.606	0.394	0.000
J18 Pneumonia, organism unspecified	0.606	0.394	0.000
S90-S99 Injuries to the ankle and foot	0.605	0.395	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.605	0.395	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.604	0.396	0.000
B48 Other mycoses, not elsewhere classified	0.603	0.396	0.000
B47 Mycetoma	0.603	0.396	0.000
B46 Zygomycosis	0.603	0.396	0.000
B45 Cryptococcosis	0.603	0.396	0.000
B43 Chromomycosis and phaeomycotic abscess	0.603	0.396	0.000
B42 Sporotrichosis	0.603	0.396	0.000
B41 Paracoccidioidomycosis	0.603	0.396	0.000
B40 Blastomycosis	0.603	0.396	0.000
B39 Histoplasmosis	0.603	0.396	0.000
B38 Coccidioidomycosis	0.603	0.396	0.000
B36 Other superficial mycoses	0.603	0.396	0.000
A60 Anogenital herpesviral [herpes simplex] infections	0.603	0.397	0.000
A59 Trichomoniasis	0.603	0.397	0.000
A56 Other sexually transmitted chlamydial diseases	0.603	0.397	0.000
A54 Gonococcal infection	0.603	0.397	0.000
A53 Other and unspecified syphilis	0.603	0.397	0.000
A52 Late syphilis	0.603	0.397	0.000
A51 Early syphilis	0.603	0.397	0.000
A50 Congenital syphilis	0.603	0.397	0.000
A64 Unspecified sexually transmitted disease	0.603	0.397	0.000
A58 Granuloma inguinale	0.603	0.397	0.000
A57 Chancroid	0.603	0.397	0.000
A55 Chlamydial lymphogranuloma (venereum)	0.603	0.397	0.000
S82.2 Fracture of shaft of tibia	0.603	0.397	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.602	0.398	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.602	0.398	0.000
G41.9 Status epilepticus, unspecified	0.601	0.399	0.000
S65 Injury of blood vessels at wrist and hand level	0.600	0.399	0.000
I74 Arterial embolism and thrombosis	0.600	0.399	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.599	0.401	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.599	0.401	0.000
Q07 Other congenital malformations of nervous system	0.598	0.402	0.000
Q06 Other congenital malformations of spinal cord	0.598	0.402	0.000
Q04 Other congenital malformations of brain	0.598	0.402	0.000
Q03 Congenital hydrocephalus	0.598	0.402	0.000
Q01 Encephalocele	0.598	0.402	0.000
Q00 Anencephaly and similar malformations	0.598	0.402	0.000
Q02 Microcephaly	0.598	0.402	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.598	0.402	0.000
D03.5 Melanoma in situ of trunk	0.596	0.404	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.596	0.404	0.000
S17 Crushing injury of neck	0.596	0.404	0.000
S15 Injury of blood vessels at neck level	0.596	0.404	0.000
S14 Injury of nerves and spinal cord at neck level	0.596	0.404	0.000
S11 Open wound of neck	0.596	0.404	0.000
S18 Traumatic amputation at neck level	0.596	0.404	0.000
S16 Injury of muscle and tendon at neck level	0.596	0.404	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.596	0.404	0.000
G47 Sleep disorders	0.596	0.404	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.595	0.404	0.000
F70-F79 Mental retardation	0.595	0.404	0.000
H91.3 Deaf mutism, not elsewhere classified	0.595	0.405	0.000
H91.2 Sudden idiopathic hearing loss	0.595	0.405	0.000
H91.1 Presbycusis	0.595	0.405	0.000
H91.0 Ototoxic hearing loss	0.595	0.405	0.000
X84 Intentional self-harm by unspecified means	0.593	0.406	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations