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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs77955971
log Bayes Factor = 21.554
Chromosome 6   position 5,128,348  (GRCh37) Explore rs77955971 on Ensembl!
Variant rs77955971 is part of Cluster X0290

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I10-I15 Hypertensive diseases
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
I10 Essential (primary) hypertension
1.000 0.000 0.000
Z86 Personal history of certain other diseases
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Z86.4 Personal history of psychoactive substance abuse
0.999 0.001 0.000
N40-N51 Diseases of male genital organs
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
Chapter II Neoplasms
0.996 0.004 0.000
I25 Chronic ischaemic heart disease
0.995 0.005 0.000
N20-N23 Urolithiasis
0.994 0.006 0.000
M80-M85 Disorders of bone density and structure
0.992 0.008 0.000
Z87 Personal history of other diseases and conditions
0.989 0.011 0.000
N20 Calculus of kidney and ureter
0.989 0.011 0.000
N40 Hyperplasia of prostate
0.989 0.011 0.000
D10-D36 Benign neoplasms
0.987 0.013 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.987 0.013 0.000
I60-I69 Cerebrovascular diseases
0.982 0.018 0.000
N20.1 Calculus of ureter
0.982 0.018 0.000
I24 Other acute ischaemic heart diseases
0.979 0.021 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.976 0.024 0.000
C60-C63 Malignant neoplasms of male genital organs
0.972 0.028 0.000
Chapter XX External causes of morbidity and mortality
0.968 0.032 0.000
M20-M25 Other joint disorders
0.967 0.033 0.000
Chapter VIII Diseases of the ear and mastoid process
0.967 0.033 0.000
I25.2 Old myocardial infarction
0.967 0.033 0.000
D12.2 Ascending colon
0.966 0.034 0.000
M81 Osteoporosis without pathological fracture
0.959 0.041 0.000
Chapter VI Diseases of the nervous system
0.957 0.043 0.000
C61 Malignant neoplasm of prostate
0.957 0.043 0.000
E70-E90 Metabolic disorders
0.955 0.045 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.953 0.047 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.952 0.048 0.000
I24.8 Other forms of acute ischaemic heart disease
0.951 0.049 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.945 0.055 0.000
Chapter X Diseases of the respiratory system
0.944 0.056 0.000
G40-G47 Episodic and paroxysmal disorders
0.942 0.058 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.941 0.059 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.937 0.063 0.000
I21 Acute myocardial infarction
0.927 0.073 0.000
M81.9 Osteoporosis, unspecified
0.926 0.074 0.000
H65-H75 Diseases of middle ear and mastoid
0.924 0.076 0.000
D12.0 Caecum
0.921 0.079 0.000
M23 Internal derangement of knee
0.921 0.079 0.000
J20-J22 Other acute lower respiratory infections
0.921 0.079 0.000
Z98 Other postsurgical states
0.919 0.081 0.000
D12.5 Sigmoid colon
0.916 0.084 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.914 0.086 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.914 0.086 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.913 0.087 0.000
M05-M14 Inflammatory polyarthropathies
0.909 0.091 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.905 0.095 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.905 0.095 0.000
J22 Unspecified acute lower respiratory infection
0.905 0.095 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.903 0.097 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.902 0.098 0.000
M80 Osteoporosis with pathological fracture
0.899 0.101 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.896 0.104 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.895 0.105 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.895 0.105 0.000
Z92 Personal history of medical treatment
0.892 0.108 0.000
Z85 Personal history of malignant neoplasm
0.890 0.110 0.000
S60-S69 Injuries to the wrist and hand
0.890 0.110 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.888 0.112 0.000
G43 Migraine
0.886 0.114 0.000
N00-N08 Glomerular diseases
0.882 0.118 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.881 0.119 0.000
I74 Arterial embolism and thrombosis
0.879 0.121 0.000
Chapter VII Diseases of the eye and adnexa
0.879 0.121 0.000
N10-N16 Renal tubulo-interstitial diseases
0.876 0.124 0.000
J40-J47 Chronic lower respiratory diseases
0.876 0.124 0.000
T92 Sequelae of injuries of upper limb
0.875 0.125 0.000
M06 Other rheumatoid arthritis
0.868 0.132 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.867 0.133 0.000
Z98.0 Intestinal bypass and anastomosis status
0.866 0.134 0.000
Z97 Presence of other devices
0.866 0.134 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.866 0.134 0.000
N23 Unspecified renal colic
0.864 0.136 0.000
E87.2 Acidosis
0.863 0.137 0.000
E00-E07 Disorders of thyroid gland
0.863 0.137 0.000
S62 Fracture at wrist and hand level
0.857 0.143 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.855 0.145 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.854 0.146 0.000
E89.0 Postprocedural hypothyroidism
0.853 0.147 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.850 0.150 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.847 0.153 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.846 0.154 0.000
M06.9 Rheumatoid arthritis, unspecified
0.841 0.159 0.000
M70-M79 Other soft tissue disorders
0.841 0.159 0.000
D12.4 Descending colon
0.840 0.160 0.000
G40 Epilepsy
0.840 0.160 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.840 0.160 0.000
C43 Malignant melanoma of skin
0.839 0.161 0.000
I69 Sequelae of cerebrovascular disease
0.836 0.164 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.831 0.169 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.831 0.169 0.000
N20.0 Calculus of kidney
0.830 0.170 0.000
G43.9 Migraine, unspecified
0.830 0.170 0.000
N41 Inflammatory diseases of prostate
0.829 0.171 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.826 0.174 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.826 0.174 0.000
T93 Sequelae of injuries of lower limb
0.825 0.175 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.824 0.176 0.000
I73 Other peripheral vascular diseases
0.822 0.178 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.822 0.178 0.000
M85 Other disorders of bone density and structure
0.822 0.178 0.000
E87.0 Hyperosmolality and hypernatraemia
0.820 0.180 0.000
M86-M90 Other osteopathies
0.820 0.180 0.000
Z86.7 Personal history of diseases of the circulatory system
0.819 0.181 0.000
I25.4 Coronary artery aneurysm
0.819 0.181 0.000
N17-N19 Renal failure
0.819 0.181 0.000
D12.9 Anus and anal canal
0.818 0.182 0.000
N45 Orchitis and epididymitis
0.818 0.182 0.000
I62 Other nontraumatic intracranial haemorrhage
0.818 0.182 0.000
Z90.2 Acquired absence of lung [part of]
0.817 0.183 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.816 0.184 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.816 0.184 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.815 0.185 0.000
G90-G99 Other disorders of the nervous system
0.815 0.185 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.814 0.186 0.000
S10-S19 Injuries to the neck
0.814 0.186 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.812 0.188 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.811 0.189 0.000
H80-H83 Diseases of inner ear
0.811 0.189 0.000
Z89 Acquired absence of limb
0.811 0.189 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.810 0.190 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.810 0.190 0.000
S62.6 Fracture of other finger
0.809 0.191 0.000
T66-T78 Other and unspecified effects of external causes
0.808 0.192 0.000
H60-H62 Diseases of external ear
0.808 0.192 0.000
I61 Intracerebral haemorrhage
0.807 0.193 0.000
N03 Chronic nephritic syndrome
0.807 0.193 0.000
E78.8 Other disorders of lipoprotein metabolism
0.806 0.194 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.806 0.194 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.804 0.196 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.804 0.196 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.804 0.196 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.803 0.197 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.799 0.201 0.000
N42 Other disorders of prostate
0.799 0.201 0.000
Z90.5 Acquired absence of kidney
0.797 0.203 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.797 0.203 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.797 0.203 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.796 0.204 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.793 0.207 0.000
Z87.8 Personal history of other specified conditions
0.793 0.207 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.793 0.207 0.000
D12.3 Transverse colon
0.792 0.208 0.000
H04 Disorders of lachrymal system
0.791 0.209 0.000
M21 Other acquired deformities of limbs
0.791 0.209 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.790 0.210 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.789 0.211 0.000
D24 Benign neoplasm of breast
0.789 0.211 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.788 0.212 0.000
H71 Cholesteatoma of middle ear
0.788 0.212 0.000
Chapter XXII Codes for special purposes
0.786 0.214 0.000
D29 Benign neoplasm of male genital organs
0.784 0.216 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.783 0.217 0.000
D23 Other benign neoplasms of skin
0.782 0.218 0.000
Z46 Fitting and adjustment of other devices
0.781 0.219 0.000
M23.4 Loose body in knee
0.779 0.221 0.000
M84 Disorders of continuity of bone
0.779 0.221 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.778 0.222 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.778 0.222 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.777 0.223 0.000
H65 Nonsuppurative otitis media
0.776 0.224 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.774 0.226 0.000
S62.60 Fracture of other finger (closed)
0.771 0.229 0.000
G47 Sleep disorders
0.770 0.230 0.000
M23.8 Other internal derangements of knee
0.770 0.230 0.000
M24 Other specific joint derangements
0.769 0.231 0.000
M81.4 Drug-induced osteoporosis
0.769 0.231 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.768 0.231 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.768 0.232 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.768 0.232 0.000
E20-E35 Disorders of other endocrine glands
0.768 0.232 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.768 0.232 0.000
D16 Benign neoplasm of bone and articular cartilage
0.768 0.232 0.000
I60 Subarachnoid haemorrhage
0.767 0.233 0.000
Z46.6 Fitting and adjustment of urinary device
0.767 0.233 0.000
V10-V19 Pedal cyclist injured in transport accident
0.766 0.234 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.764 0.236 0.000
V40-V49 Car occupant injured in transport accident
0.764 0.236 0.000
N13 Obstructive and reflux uropathy
0.763 0.237 0.000
J47 Bronchiectasis
0.757 0.243 0.000
Z90.3 Acquired absence of part of stomach
0.756 0.244 0.000
E40-E46 Malnutrition
0.756 0.244 0.000
S90-S99 Injuries to the ankle and foot
0.755 0.245 0.000
Z83 Family history of other specific disorders
0.755 0.245 0.000
D11 Benign neoplasm of major salivary glands
0.754 0.246 0.000
N03.9 Unspecified
0.753 0.247 0.000
H02 Other disorders of eyelid
0.753 0.247 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.753 0.247 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.753 0.247 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.752 0.248 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.752 0.248 0.000
I11 Hypertensive heart disease
0.752 0.248 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.751 0.249 0.000
M05 Seropositive rheumatoid arthritis
0.751 0.249 0.000
D36 Benign neoplasm of other and unspecified sites
0.751 0.249 0.000
M20 Acquired deformities of fingers and toes
0.747 0.253 0.000
E87.5 Hyperkalaemia
0.746 0.254 0.000
E07 Other disorders of thyroid
0.745 0.255 0.000
N99-N99 Other disorders of the genitourinary system
0.745 0.255 0.000
M79.6 Pain in limb
0.745 0.255 0.000
N50 Other disorders of male genital organs
0.744 0.256 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.744 0.256 0.000
W00-W19 Falls
0.744 0.256 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.743 0.257 0.000
N41.0 Acute prostatitis
0.743 0.257 0.000
H73 Other disorders of tympanic membrane
0.743 0.257 0.000
D12.6 Colon, unspecified
0.740 0.260 0.000
H10-H13 Disorders of conjunctiva
0.740 0.260 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.740 0.260 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.739 0.261 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.738 0.262 0.000
M35 Other systemic involvement of connective tissue
0.737 0.263 0.000
D32 Benign neoplasm of meninges
0.736 0.264 0.000
H04.2 Epiphora
0.734 0.266 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.734 0.266 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.734 0.266 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.733 0.267 0.000
D12.7 Rectosigmoid junction
0.730 0.270 0.000
M91-M94 Chondropathies
0.728 0.272 0.000
G44 Other headache syndromes
0.726 0.274 0.000
Z98.1 Arthrodesis status
0.726 0.274 0.000
N18 Chronic renal failure
0.725 0.275 0.000
S50-S59 Injuries to the elbow and forearm
0.725 0.275 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.724 0.276 0.000
H66 Suppurative and unspecified otitis media
0.724 0.276 0.000
Z87.0 Personal history of diseases of the respiratory system
0.724 0.276 0.000
J42 Unspecified chronic bronchitis
0.723 0.277 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.722 0.278 0.000
N48 Other disorders of penis
0.721 0.279 0.000
Z97.4 Presence of external hearing-aid
0.720 0.280 0.000
I69.3 Sequelae of cerebral infarction
0.720 0.280 0.000
Z94 Transplanted organ and tissue status
0.718 0.282 0.000
T79-T79 Certain early complications of trauma
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I15 Secondary hypertension
0.717 0.283 0.000
I13 Hypertensive heart and renal disease
0.717 0.283 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.717 0.283 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
C64-C68 Malignant neoplasms of urinary tract
0.716 0.284 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.716 0.284 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.716 0.284 0.000
N46 Male infertility
0.716 0.284 0.000
N44 Torsion of testis
0.716 0.284 0.000
T33-T35 Frostbite
0.714 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.714 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.285 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.286 0.000
D34 Benign neoplasm of thyroid gland
0.714 0.286 0.000
T90 Sequelae of injuries of head
0.713 0.287 0.000
I25.6 Silent myocardial ischaemia
0.713 0.287 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.713 0.287 0.000
I72 Other aneurysm
0.713 0.287 0.000
E87.6 Hypokalaemia
0.712 0.288 0.000
M83 Adult osteomalacia
0.711 0.289 0.000
M82 Osteoporosis in diseases classified elsewhere
0.711 0.289 0.000
J44 Other chronic obstructive pulmonary disease
0.711 0.289 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.710 0.290 0.000
H69 Other disorders of Eustachian tube
0.709 0.290 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.709 0.291 0.000
N20.9 Urinary calculus, unspecified
0.709 0.291 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.709 0.291 0.000
L10-L14 Bullous disorders
0.708 0.292 0.000
W20-W49 Exposure to inanimate mechanical forces
0.708 0.292 0.000
H83 Other diseases of inner ear
0.708 0.292 0.000
D31 Benign neoplasm of eye and adnexa
0.708 0.292 0.000
D30 Benign neoplasm of urinary organs
0.708 0.292 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.708 0.292 0.000
D19 Benign neoplasm of mesothelial tissue
0.708 0.292 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.708 0.292 0.000
D12.1 Appendix
0.708 0.292 0.000
Z03.8 Observation for other suspected diseases and conditions
0.707 0.293 0.000
Z80 Family history of malignant neoplasm
0.707 0.293 0.000
G43.1 Migraine with aura [classical migraine]
0.706 0.294 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.706 0.294 0.000
I73.9 Peripheral vascular disease, unspecified
0.705 0.295 0.000
Z91.5 Personal history of self-harm
0.705 0.295 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.704 0.296 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.704 0.296 0.000
E88 Other metabolic disorders
0.704 0.296 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.704 0.296 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.703 0.297 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.703 0.297 0.000
I05-I09 Chronic rheumatic heart diseases
0.702 0.298 0.000
J46 Status asthmaticus
0.702 0.298 0.000
I24.1 Dressler's syndrome
0.702 0.298 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.702 0.298 0.000
G95 Other diseases of spinal cord
0.701 0.299 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.701 0.299 0.000
D26 Other benign neoplasms of uterus
0.701 0.299 0.000
E06 Thyroiditis
0.701 0.299 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.700 0.300 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.700 0.300 0.000
M85.8 Other specified disorders of bone density and structure
0.699 0.301 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.699 0.301 0.000
M07 Psoriatic and enteropathic arthropathies
0.699 0.301 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.698 0.302 0.000
I25.3 Aneurysm of heart
0.698 0.302 0.000
M31 Other necrotising vasculopathies
0.698 0.302 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.697 0.303 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.697 0.303 0.000
C60 Malignant neoplasm of penis
0.697 0.303 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.697 0.303 0.000
T91 Sequelae of injuries of neck and trunk
0.696 0.304 0.000
I78 Diseases of capillaries
0.696 0.304 0.000
V80-V89 Other land transport accidents
0.695 0.304 0.000
Y35-Y36 Legal intervention and operations of war
0.694 0.306 0.000
Y10-Y34 Event of undetermined intent
0.694 0.306 0.000
Y00-Y09 Assault
0.694 0.306 0.000
X85-X99 Assault
0.694 0.306 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.694 0.306 0.000
X50-X57 Overexertion, travel and privation
0.694 0.306 0.000
X30-X39 Exposure to forces of nature
0.694 0.306 0.000
X20-X29 Contact with venomous animals and plants
0.694 0.306 0.000
X10-X19 Contact with heat and hot substances
0.694 0.306 0.000
X00-X09 Exposure to smoke, fire and flames
0.694 0.306 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.694 0.306 0.000
W75-W84 Other accidental threats to breathing
0.694 0.306 0.000
W65-W74 Accidental drowning and submersion
0.694 0.306 0.000
W50-W64 Exposure to animate mechanical forces
0.694 0.306 0.000
V98-V99 Other and unspecified transport accidents
0.694 0.306 0.000
V95-V97 Air and space transport accidents
0.694 0.306 0.000
V90-V94 Water transport accidents
0.694 0.306 0.000
V70-V79 Bus occupant injured in transport accident
0.694 0.306 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.694 0.306 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.694 0.306 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.694 0.306 0.000
V01-V09 Pedestrian injured in transport accident
0.694 0.306 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.694 0.306 0.000
M34 Systemic sclerosis
0.694 0.306 0.000
M33 Dermatopolymyositis
0.694 0.306 0.000
M32 Systemic lupus erythematosus
0.694 0.306 0.000
M30 Polyarteritis nodosa and related conditions
0.694 0.306 0.000
M45-M49 Spondylopathies
0.693 0.307 0.000
M65-M68 Disorders of synovium and tendon
0.693 0.307 0.000
H72 Perforation of tympanic membrane
0.692 0.308 0.000
J60-J70 Lung diseases due to external agents
0.691 0.309 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.691 0.309 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.691 0.309 0.000
Q50-Q56 Congenital malformations of genital organs
0.689 0.310 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.689 0.311 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.689 0.311 0.000
Chapter V Mental and behavioural disorders
0.689 0.311 0.000
T93.2 Sequelae of other fractures of lower limb
0.688 0.312 0.000
M81.8 Other osteoporosis
0.688 0.312 0.000
M81.6 Localised osteoporosis [Lequesne]
0.688 0.312 0.000
M81.5 Idiopathic osteoporosis
0.688 0.312 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.688 0.312 0.000
M81.2 Osteoporosis of disuse
0.688 0.312 0.000
M81.1 Postoophorectomy osteoporosis
0.688 0.312 0.000
M81.0 Postmenopausal osteoporosis
0.688 0.312 0.000
J90-J94 Other diseases of pleura
0.688 0.312 0.000
G41 Status epilepticus
0.688 0.312 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.687 0.313 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.687 0.313 0.000
G70-G73 Diseases of myoneural junction and muscle
0.686 0.313 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.686 0.314 0.000
I95 Hypotension
0.686 0.314 0.000
Y95 Nosocomial condition
0.686 0.314 0.000
H05 Disorders of orbit
0.685 0.315 0.000
I74.5 Embolism and thrombosis of iliac artery
0.685 0.315 0.000
E85 Amyloidosis
0.684 0.315 0.000
E84 Cystic fibrosis
0.684 0.315 0.000
E79 Disorders of purine and pyrimidine metabolism
0.684 0.315 0.000
E77 Disorders of glycoprotein metabolism
0.684 0.315 0.000
E76 Disorders of glycosaminoglycan metabolism
0.684 0.315 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.684 0.315 0.000
E74 Other disorders of carbohydrate metabolism
0.684 0.315 0.000
E73 Lactose intolerance
0.684 0.315 0.000
E72 Other disorders of amino-acid metabolism
0.684 0.315 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.684 0.315 0.000
E70 Disorders of aromatic amino-acid metabolism
0.684 0.315 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.684 0.315 0.000
S69 Other and unspecified injuries of wrist and hand
0.684 0.315 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.684 0.316 0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.684 0.316 0.000
T98 Sequelae of other and unspecified effects of external causes
0.683 0.317 0.000
T95 Sequelae of burns, corrosions and frostbite
0.683 0.317 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.683 0.317 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.683 0.317 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.683 0.317 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.683 0.317 0.000
M22 Disorders of patella
0.683 0.317 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.681 0.319 0.000
L08 Other local infections of skin and subcutaneous tissue
0.681 0.319 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.680 0.320 0.000
S62.4 Multiple fractures of metacarpal bones
0.680 0.320 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.679 0.321 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.678 0.321 0.000
I21.9 Acute myocardial infarction, unspecified
0.678 0.322 0.000
C45 Mesothelioma
0.678 0.322 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.678 0.322 0.000
E78.4 Other hyperlipidaemia
0.678 0.322 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.677 0.323 0.000
M23.49 Loose body in knee-Unspec lig/men
0.677 0.323 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.677 0.323 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.676 0.323 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.676 0.324 0.000
H65.3 Chronic mucoid otitis media
0.675 0.325 0.000
Q60-Q64 Congenital malformations of the urinary system
0.675 0.325 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.674 0.325 0.000
S80-S89 Injuries to the knee and lower leg
0.674 0.326 0.000
Z46.8 Fitting and adjustment of other specified devices
0.674 0.326 0.000
N20.2 Calculus of kidney with calculus of ureter
0.674 0.326 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.673 0.327 0.000
S70-S79 Injuries to the hip and thigh
0.673 0.327 0.000
Q23 Congenital malformations of aortic and mitral valves
0.673 0.327 0.000
G90 Disorders of autonomic nervous system
0.672 0.328 0.000
Q80-Q89 Other congenital malformations
0.672 0.328 0.000
T17 Foreign body in respiratory tract
0.672 0.328 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.671 0.329 0.000
T92.0 Sequelae of open wound of upper limb
0.671 0.329 0.000
N18.9 Chronic renal failure, unspecified
0.670 0.330 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.670 0.330 0.000
L60-L75 Disorders of skin appendages
0.670 0.330 0.000
H61 Other disorders of external ear
0.669 0.331 0.000
M20.0 Deformity of finger(s)
0.669 0.331 0.000
S62.5 Fracture of thumb
0.668 0.332 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.668 0.332 0.000
Z92.8 Personal history of other medical treatment
0.668 0.332 0.000
Z97.8 Presence of other specified devices
0.668 0.332 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.667 0.333 0.000
Q00-Q07 Congenital malformations of the nervous system
0.667 0.333 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.666 0.334 0.000
Z93 Artificial opening status
0.666 0.334 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.665 0.335 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.665 0.335 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.665 0.335 0.000
S20-S29 Injuries to the thorax
0.664 0.336 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.664 0.336 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.664 0.336 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.664 0.336 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.664 0.336 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.664 0.336 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.664 0.336 0.000
D23.7 Skin of lower limb, including hip
0.664 0.336 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.664 0.336 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.663 0.336 0.000
I70 Atherosclerosis
0.663 0.337 0.000
M20.4 Other hammer toe(s) (acquired)
0.663 0.337 0.000
C62 Malignant neoplasm of testis
0.663 0.337 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.662 0.338 0.000
H70 Mastoiditis and related conditions
0.662 0.338 0.000
H68 Eustachian salpingitis and obstruction
0.662 0.338 0.000
H67 Otitis media in diseases classified elsewhere
0.662 0.338 0.000
T68 Hypothermia
0.662 0.338 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.662 0.338 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.661 0.338 0.000
Z47 Other orthopaedic follow-up care
0.661 0.339 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.661 0.339 0.000
M23.5 Chronic instability of knee
0.661 0.339 0.000
D00-D09 In situ neoplasms
0.661 0.339 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.661 0.339 0.000
E07.9 Disorder of thyroid, unspecified
0.661 0.339 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.661 0.339 0.000
M23.9 Internal derangement of knee, unspecified
0.660 0.340 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.660 0.340 0.000
M23.1 Discoid meniscus (congenital)
0.660 0.340 0.000
M23.0 Cystic meniscus
0.660 0.340 0.000
J21 Acute bronchiolitis
0.660 0.340 0.000
J20 Acute bronchitis
0.660 0.340 0.000
M81.98 Osteoporosis, unspecified (Other)
0.659 0.341 0.000
M79.5 Residual foreign body in soft tissue
0.658 0.342 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.656 0.344 0.000
J45 Asthma
0.656 0.344 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.655 0.345 0.000
E87.4 Mixed disorder of acid-base balance
0.655 0.345 0.000
E87.3 Alkalosis
0.655 0.345 0.000
H02.8 Other specified disorders of eyelid
0.655 0.345 0.000
D21.0 Connective and other soft tissue of head, face and neck
0.655 0.345 0.000
M79.60 Pain in limb (Multiple sites)
0.655 0.345 0.000
G20-G26 Extrapyramidal and movement disorders
0.655 0.345 0.000
S12 Fracture of neck
0.654 0.346 0.000
I12 Hypertensive renal disease
0.654 0.346 0.000
H00 Hordeolum and chalazion
0.654 0.346 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.654 0.346 0.000
I73.0 Raynaud's syndrome
0.653 0.347 0.000
E78.2 Mixed hyperlipidaemia
0.652 0.348 0.000
N48.8 Other specified disorders of penis
0.652 0.348 0.000
M14 Arthropathies in other diseases classified elsewhere
0.652 0.348 0.000
M12 Other specific arthropathies
0.652 0.348 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.652 0.348 0.000
M08 Juvenile arthritis
0.652 0.348 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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