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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78013963
log Bayes Factor = 20.4998
Chromosome 20   position 35,598,026  (GRCh37) Explore rs78013963 on Ensembl!
Variant rs78013963 is part of Cluster X0290

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
N30-N39 Other diseases of urinary system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.996 0.004 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.994 0.006 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.993 0.007 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.991 0.009 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.990 0.010 0.000
N20-N23 Urolithiasis
0.985 0.015 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.985 0.015 0.000
M20-M25 Other joint disorders
0.982 0.018 0.000
Chapter VII Diseases of the eye and adnexa
0.980 0.020 0.000
I10-I15 Hypertensive diseases
0.979 0.021 0.000
N10-N16 Renal tubulo-interstitial diseases
0.978 0.022 0.000
I77 Other disorders of arteries and arterioles
0.977 0.023 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.975 0.025 0.000
N35 Urethral stricture
0.975 0.025 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.970 0.030 0.000
N95 Menopausal and other perimenopausal disorders
0.969 0.031 0.000
Chapter V Mental and behavioural disorders
0.969 0.031 0.000
Chapter II Neoplasms
0.967 0.033 0.000
I60-I69 Cerebrovascular diseases
0.964 0.036 0.000
N95.0 Postmenopausal bleeding
0.964 0.036 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.963 0.037 0.000
I10 Essential (primary) hypertension
0.963 0.037 0.000
C15-C26 Malignant neoplasms of digestive organs
0.963 0.037 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.962 0.038 0.000
N20 Calculus of kidney and ureter
0.962 0.038 0.000
C18 Malignant neoplasm of colon
0.960 0.040 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.960 0.040 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.957 0.043 0.000
N35.9 Urethral stricture, unspecified
0.957 0.043 0.000
I20-I25 Ischaemic heart diseases
0.956 0.044 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.955 0.045 0.000
Z53.0 Procedure not carried out because of contraindication
0.951 0.049 0.000
N32 Other disorders of bladder
0.949 0.051 0.000
S20-S29 Injuries to the thorax
0.948 0.051 0.000
I73 Other peripheral vascular diseases
0.943 0.057 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.943 0.057 0.000
S00-S09 Injuries to the head
0.943 0.057 0.000
Z51 Other medical care
0.942 0.058 0.000
I77.1 Stricture of artery
0.942 0.058 0.000
N17-N19 Renal failure
0.941 0.059 0.000
R07 Pain in throat and chest
0.939 0.061 0.000
R07.4 Chest pain, unspecified
0.936 0.064 0.000
M35 Other systemic involvement of connective tissue
0.928 0.072 0.000
M23 Internal derangement of knee
0.927 0.073 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.924 0.076 0.000
Z51.5 Palliative care
0.924 0.076 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.919 0.081 0.000
N13 Obstructive and reflux uropathy
0.912 0.088 0.000
N39 Other disorders of urinary system
0.911 0.089 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.910 0.090 0.000
N20.0 Calculus of kidney
0.908 0.092 0.000
C18.7 Sigmoid colon
0.907 0.093 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.907 0.093 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.904 0.096 0.000
H30-H36 Disorders of choroid and retina
0.903 0.097 0.000
N30 Cystitis
0.899 0.101 0.000
N18 Chronic renal failure
0.898 0.102 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.897 0.103 0.000
Z46 Fitting and adjustment of other devices
0.896 0.104 0.000
R25 Abnormal involuntary movements
0.895 0.105 0.000
M15-M19 Arthrosis
0.892 0.108 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.891 0.109 0.000
M35.3 Polymyalgia rheumatica
0.889 0.111 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.887 0.112 0.000
I24 Other acute ischaemic heart diseases
0.887 0.113 0.000
Z51.3 Blood transfusion without reported diagnosis
0.885 0.115 0.000
C18.2 Ascending colon
0.883 0.117 0.000
N23 Unspecified renal colic
0.881 0.119 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.877 0.123 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.875 0.125 0.000
R26 Abnormalities of gait and mobility
0.875 0.125 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.871 0.129 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.871 0.129 0.000
E10-E14 Diabetes mellitus
0.866 0.134 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.866 0.134 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.866 0.134 0.000
I73.9 Peripheral vascular disease, unspecified
0.866 0.134 0.000
I74 Arterial embolism and thrombosis
0.863 0.137 0.000
I77.6 Arteritis, unspecified
0.863 0.137 0.000
N86 Erosion and ectropion of cervix uteri
0.861 0.139 0.000
N18.9 Chronic renal failure, unspecified
0.860 0.140 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.857 0.143 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.855 0.145 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.854 0.146 0.000
M31 Other necrotising vasculopathies
0.854 0.146 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.854 0.146 0.000
Z03.1 Observation for suspected malignant neoplasm
0.849 0.151 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.848 0.152 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.848 0.152 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.844 0.156 0.000
M65-M68 Disorders of synovium and tendon
0.842 0.158 0.000
I24.8 Other forms of acute ischaemic heart disease
0.841 0.159 0.000
N32.0 Bladder-neck obstruction
0.841 0.159 0.000
N20.1 Calculus of ureter
0.838 0.162 0.000
I63 Cerebral infarction
0.836 0.164 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.836 0.164 0.000
Z03.8 Observation for other suspected diseases and conditions
0.835 0.165 0.000
R04 Haemorrhage from respiratory passages
0.834 0.166 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.834 0.166 0.000
I25 Chronic ischaemic heart disease
0.831 0.169 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.829 0.171 0.000
Z46.6 Fitting and adjustment of urinary device
0.828 0.172 0.000
R30-R39 Symptoms and signs involving the urinary system
0.825 0.175 0.000
S27 Injury of other and unspecified intrathoracic organs
0.824 0.176 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.824 0.176 0.000
H52 Disorders of refraction and accommodation
0.823 0.177 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.823 0.177 0.000
R79 Other abnormal findings of blood chemistry
0.822 0.178 0.000
D50-D53 Nutritional anaemias
0.818 0.182 0.000
E10 Insulin-dependent diabetes mellitus
0.818 0.182 0.000
C18.3 Hepatic flexure
0.815 0.185 0.000
N85.0 Endometrial glandular hyperplasia
0.815 0.185 0.000
S06 Intracranial injury
0.812 0.188 0.000
I73.0 Raynaud's syndrome
0.812 0.188 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.812 0.188 0.000
R47-R49 Symptoms and signs involving speech and voice
0.809 0.191 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.807 0.193 0.000
R31 Unspecified haematuria
0.807 0.193 0.000
N32.8 Other specified disorders of bladder
0.806 0.194 0.000
C51-C58 Malignant neoplasms of female genital organs
0.805 0.195 0.000
S02 Fracture of skull and facial bones
0.805 0.195 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.805 0.195 0.000
N32.3 Diverticulum of bladder
0.805 0.195 0.000
I67 Other cerebrovascular diseases
0.802 0.198 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.799 0.201 0.000
C18.9 Colon, unspecified
0.798 0.202 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.798 0.202 0.000
Z75 Problems related to medical facilities and other health care
0.796 0.204 0.000
Chapter XX External causes of morbidity and mortality
0.796 0.204 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.795 0.205 0.000
N39.0 Urinary tract infection, site not specified
0.791 0.209 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.790 0.210 0.000
N39.4 Other specified urinary incontinence
0.789 0.211 0.000
H35 Other retinal disorders
0.788 0.212 0.000
M25 Other joint disorders, not elsewhere classified
0.785 0.215 0.000
Z03.4 Observation for suspected myocardial infarction
0.784 0.216 0.000
R04.0 Epistaxis
0.783 0.217 0.000
N30.8 Other cystitis
0.783 0.217 0.000
R06 Abnormalities of breathing
0.782 0.218 0.000
R00 Abnormalities of heart beat
0.781 0.219 0.000
M45-M49 Spondylopathies
0.780 0.220 0.000
F41 Other anxiety disorders
0.780 0.220 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.779 0.221 0.000
Z71.8 Other specified counselling
0.779 0.221 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.777 0.223 0.000
M23.3 Other meniscus derangements
0.776 0.224 0.000
R25.1 Tremor, unspecified
0.775 0.225 0.000
I60 Subarachnoid haemorrhage
0.775 0.225 0.000
N20.2 Calculus of kidney with calculus of ureter
0.774 0.226 0.000
H25-H28 Disorders of lens
0.774 0.226 0.000
S00 Superficial injury of head
0.773 0.226 0.000
D60-D64 Aplastic and other anaemias
0.772 0.228 0.000
N93 Other abnormal uterine and vaginal bleeding
0.772 0.228 0.000
N19 Unspecified renal failure
0.768 0.232 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.768 0.232 0.000
D80-D89 Certain disorders involving the immune mechanism
0.768 0.232 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.767 0.233 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.767 0.233 0.000
F10.0 Acute intoxication
0.767 0.233 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.767 0.233 0.000
H53-H54 Visual disturbances and blindness
0.765 0.235 0.000
C18.0 Caecum
0.764 0.236 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.764 0.236 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.763 0.237 0.000
N36 Other disorders of urethra
0.762 0.238 0.000
Z72 Problems related to lifestyle
0.762 0.238 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.760 0.240 0.000
D00-D09 In situ neoplasms
0.759 0.241 0.000
S22.3 Fracture of rib
0.758 0.242 0.000
T93 Sequelae of injuries of lower limb
0.758 0.242 0.000
N13.3 Other and unspecified hydronephrosis
0.757 0.243 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.756 0.244 0.000
S09 Other and unspecified injuries of head
0.755 0.245 0.000
C15 Malignant neoplasm of oesophagus
0.754 0.246 0.000
M16 Coxarthrosis [arthrosis of hip]
0.754 0.246 0.000
I63.8 Other cerebral infarction
0.753 0.247 0.000
T66-T78 Other and unspecified effects of external causes
0.752 0.248 0.000
H52.1 Myopia
0.752 0.248 0.000
R02 Gangrene, not elsewhere classified
0.750 0.250 0.000
N99-N99 Other disorders of the genitourinary system
0.750 0.250 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.749 0.251 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.748 0.252 0.000
M17 Gonarthrosis [arthrosis of knee]
0.746 0.254 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.745 0.255 0.000
N85.4 Malposition of uterus
0.745 0.255 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.744 0.256 0.000
H10-H13 Disorders of conjunctiva
0.743 0.256 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.743 0.257 0.000
T90 Sequelae of injuries of head
0.742 0.258 0.000
T91 Sequelae of injuries of neck and trunk
0.742 0.258 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.741 0.259 0.000
I70 Atherosclerosis
0.739 0.261 0.000
M22 Disorders of patella
0.738 0.262 0.000
C18.4 Transverse colon
0.737 0.263 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.737 0.263 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.737 0.263 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.736 0.264 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.736 0.264 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.735 0.265 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.734 0.266 0.000
Z52 Donors of organs and tissues
0.733 0.267 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.733 0.267 0.000
T51 Toxic effect of alcohol
0.733 0.267 0.000
F10.2 Dependence syndrome
0.732 0.268 0.000
R25.3 Fasciculation
0.732 0.268 0.000
Chapter VI Diseases of the nervous system
0.731 0.269 0.000
M31.3 Wegener's granulomatosis
0.730 0.270 0.000
I80 Phlebitis and thrombophlebitis
0.729 0.271 0.000
E10.9 Without complications
0.729 0.271 0.000
H36 Retinal disorders in diseases classified elsewhere
0.728 0.272 0.000
N85.1 Endometrial adenomatous hyperplasia
0.727 0.272 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.727 0.272 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.727 0.273 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.726 0.274 0.000
H34 Retinal vascular occlusions
0.725 0.275 0.000
N80 Endometriosis
0.724 0.276 0.000
F10.1 Harmful use
0.723 0.277 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.723 0.277 0.000
T92 Sequelae of injuries of upper limb
0.721 0.279 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.721 0.279 0.000
D50 Iron deficiency anaemia
0.720 0.280 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.719 0.281 0.000
I20 Angina pectoris
0.718 0.282 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.718 0.282 0.000
C18.6 Descending colon
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N37 Urethral disorders in diseases classified elsewhere
0.717 0.283 0.000
N34 Urethritis and urethral syndrome
0.717 0.283 0.000
N33 Bladder disorders in diseases classified elsewhere
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.715 0.285 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.714 0.286 0.000
I72 Other aneurysm
0.714 0.286 0.000
Z43 Attention to artificial openings
0.714 0.286 0.000
Z73 Problems related to life-management difficulty
0.714 0.286 0.000
H55-H59 Other disorders of eye and adnexa
0.714 0.286 0.000
S80-S89 Injuries to the knee and lower leg
0.713 0.287 0.000
I12 Hypertensive renal disease
0.713 0.287 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.713 0.287 0.000
I67.9 Cerebrovascular disease, unspecified
0.712 0.288 0.000
N39.8 Other specified disorders of urinary system
0.712 0.288 0.000
Z10 Routine general health check-up of defined subpopulation
0.712 0.288 0.000
Z54 Convalescence
0.711 0.289 0.000
Z49 Care involving dialysis
0.711 0.289 0.000
Z44 Fitting and adjustment of external prosthetic device
0.711 0.289 0.000
M91-M94 Chondropathies
0.710 0.290 0.000
M60-M63 Disorders of muscles
0.710 0.290 0.000
M00-M03 Infectious arthropathies
0.710 0.290 0.000
Z42 Follow-up care involving plastic surgery
0.709 0.290 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.709 0.291 0.000
Z71.3 Dietary counselling and surveillance
0.709 0.291 0.000
N18.3 Chronic kidney disease, stage 3
0.708 0.292 0.000
M23.5 Chronic instability of knee
0.708 0.292 0.000
E10.1 With ketoacidosis
0.708 0.292 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.706 0.294 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.706 0.294 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.706 0.294 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.705 0.295 0.000
I87 Other disorders of veins
0.704 0.296 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.704 0.296 0.000
M34 Systemic sclerosis
0.704 0.296 0.000
M33 Dermatopolymyositis
0.704 0.296 0.000
M32 Systemic lupus erythematosus
0.704 0.296 0.000
M30 Polyarteritis nodosa and related conditions
0.704 0.296 0.000
M21 Other acquired deformities of limbs
0.704 0.296 0.000
M40-M43 Deforming dorsopathies
0.703 0.297 0.000
I25.1 Atherosclerotic heart disease
0.703 0.297 0.000
M24 Other specific joint derangements
0.702 0.298 0.000
Z47 Other orthopaedic follow-up care
0.702 0.298 0.000
I15 Secondary hypertension
0.702 0.298 0.000
I13 Hypertensive heart and renal disease
0.702 0.298 0.000
I11 Hypertensive heart disease
0.702 0.298 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.701 0.299 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.701 0.299 0.000
N15 Other renal tubulo-interstitial diseases
0.701 0.299 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.701 0.299 0.000
N11 Chronic tubulo-interstitial nephritis
0.701 0.299 0.000
N10 Acute tubulo-interstitial nephritis
0.701 0.299 0.000
I77.8 Other specified disorders of arteries and arterioles
0.701 0.299 0.000
I77.5 Necrosis of artery
0.701 0.299 0.000
I77.4 Coeliac artery compression syndrome
0.701 0.299 0.000
I77.3 Arterial fibromuscular dysplasia
0.701 0.299 0.000
I77.2 Rupture of artery
0.701 0.299 0.000
I77.0 Arteriovenous fistula, acquired
0.701 0.299 0.000
M18 Arthrosis of first carpometacarpal joint
0.701 0.299 0.000
I62 Other nontraumatic intracranial haemorrhage
0.700 0.300 0.000
N30.3 Trigonitis
0.700 0.300 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.699 0.300 0.000
N98 Complications associated with artificial fertilisation
0.699 0.301 0.000
N91 Absent, scanty and rare menstruation
0.699 0.301 0.000
N82 Fistulae involving female genital tract
0.699 0.301 0.000
N96 Habitual aborter
0.699 0.301 0.000
N35.8 Other urethral stricture
0.699 0.301 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.699 0.301 0.000
N35.0 Posttraumatic urethral stricture
0.699 0.301 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.699 0.301 0.000
S50-S59 Injuries to the elbow and forearm
0.698 0.301 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.698 0.302 0.000
H43-H45 Disorders of vitreous body and globe
0.698 0.302 0.000
N97 Female infertility
0.697 0.303 0.000
I22 Subsequent myocardial infarction
0.696 0.304 0.000
M86-M90 Other osteopathies
0.696 0.304 0.000
N95.9 Menopausal and perimenopausal disorder, unspecified
0.695 0.305 0.000
N95.3 States associated with artificial menopause
0.695 0.305 0.000
N95.1 Menopausal and female climacteric states
0.695 0.305 0.000
F99-F99 Unspecified mental disorder
0.694 0.305 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.694 0.305 0.000
F80-F89 Disorders of psychological development
0.694 0.305 0.000
F70-F79 Mental retardation
0.694 0.305 0.000
F60-F69 Disorders of adult personality and behaviour
0.694 0.305 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.694 0.306 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.694 0.306 0.000
Z63 Other problems related to primary support group, including family circumstances
0.694 0.306 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.693 0.306 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.693 0.306 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.693 0.306 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.693 0.306 0.000
O48 Prolonged pregnancy
0.693 0.306 0.000
Z74 Problems related to care-provider dependency
0.693 0.307 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.693 0.307 0.000
O00-O08 Pregnancy with abortive outcome
0.693 0.307 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.691 0.309 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.691 0.309 0.000
I25.5 Ischaemic cardiomyopathy
0.691 0.309 0.000
C25 Malignant neoplasm of pancreas
0.690 0.309 0.000
R27 Other lack of coordination
0.690 0.310 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.690 0.310 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.690 0.310 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.690 0.310 0.000
C21 Malignant neoplasm of anus and anal canal
0.690 0.310 0.000
C17 Malignant neoplasm of small intestine
0.690 0.310 0.000
C16 Malignant neoplasm of stomach
0.690 0.310 0.000
C23 Malignant neoplasm of gallbladder
0.690 0.310 0.000
R00.0 Tachycardia, unspecified
0.690 0.310 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.690 0.310 0.000
M65 Synovitis and tenosynovitis
0.690 0.310 0.000
N20.9 Urinary calculus, unspecified
0.689 0.311 0.000
S90-S99 Injuries to the ankle and foot
0.689 0.311 0.000
O42 Premature rupture of membranes
0.689 0.311 0.000
C18.8 Overlapping lesion of colon
0.688 0.312 0.000
C18.5 Splenic flexure
0.688 0.312 0.000
C18.1 Appendix
0.688 0.312 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.688 0.312 0.000
S22.0 Fracture of thoracic vertebra
0.688 0.312 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.688 0.312 0.000
Z03.3 Observation for suspected nervous system disorder
0.688 0.312 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.688 0.312 0.000
Z03.0 Observation for suspected tuberculosis
0.688 0.312 0.000
F43 Reaction to severe stress, and adjustment disorders
0.688 0.312 0.000
E11 Non-insulin-dependent diabetes mellitus
0.687 0.313 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.687 0.313 0.000
Z76 Persons encountering health services in other circumstances
0.686 0.313 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.686 0.313 0.000
I23 Certain current complications following acute myocardial infarction
0.685 0.314 0.000
Z01.8 Other specified special examinations
0.684 0.316 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.683 0.317 0.000
N32.4 Rupture of bladder, nontraumatic
0.681 0.319 0.000
N32.2 Vesical fistula, not elsewhere classified
0.681 0.319 0.000
N32.1 Vesicointestinal fistula
0.681 0.319 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.680 0.320 0.000
Z04 Examination and observation for other reasons
0.680 0.320 0.000
I05-I09 Chronic rheumatic heart diseases
0.680 0.320 0.000
S29 Other and unspecified injuries of thorax
0.680 0.320 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.680 0.320 0.000
S26 Injury of heart
0.680 0.320 0.000
S25 Injury of blood vessels of thorax
0.680 0.320 0.000
S24 Injury of nerves and spinal cord at thorax level
0.680 0.320 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.680 0.320 0.000
S21 Open wound of thorax
0.680 0.320 0.000
S20 Superficial injury of thorax
0.680 0.320 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.680 0.320 0.000
N30.9 Cystitis, unspecified
0.680 0.320 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.679 0.321 0.000
M17.1 Other primary gonarthrosis
0.678 0.322 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.678 0.322 0.000
S70-S79 Injuries to the hip and thigh
0.678 0.322 0.000
N88 Other noninflammatory disorders of cervix uteri
0.677 0.323 0.000
S27.1 Traumatic haemothorax
0.677 0.323 0.000
S22.30 Fracture of rib (closed)
0.677 0.323 0.000
M67 Other disorders of synovium and tendon
0.677 0.323 0.000
M31.6 Other giant cell arteritis
0.677 0.323 0.000
I73.8 Other specified peripheral vascular diseases
0.676 0.324 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.676 0.324 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.676 0.324 0.000
D55-D59 Haemolytic anaemias
0.676 0.324 0.000
I30-I52 Other forms of heart disease
0.676 0.324 0.000
S08 Traumatic amputation of part of head
0.676 0.324 0.000
S07 Crushing injury of head
0.676 0.324 0.000
S05 Injury of eye and orbit
0.676 0.324 0.000
S04 Injury of cranial nerves
0.676 0.324 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.676 0.324 0.000
Z01.9 Special examination, unspecified
0.675 0.324 0.000
Z51.9 Medical care, unspecified
0.675 0.324 0.000
Z51.6 Desensitisation to allergens
0.675 0.324 0.000
R06.4 Hyperventilation
0.675 0.325 0.000
H35.8 Other specified retinal disorders
0.674 0.326 0.000
S22.2 Fracture of sternum
0.674 0.326 0.000
R07.1 Chest pain on breathing
0.673 0.326 0.000
I82 Other venous embolism and thrombosis
0.672 0.328 0.000
H25 Senile cataract
0.671 0.329 0.000
I71 Aortic aneurysm and dissection
0.670 0.330 0.000
N89 Other noninflammatory disorders of vagina
0.669 0.331 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.669 0.331 0.000
M35.0 Sicca syndrome [Sjogren]
0.668 0.331 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.668 0.332 0.000
Z45 Adjustment and management of implanted device
0.668 0.332 0.000
S22.4 Multiple fractures of ribs
0.667 0.332 0.000
S40-S49 Injuries to the shoulder and upper arm
0.667 0.333 0.000
H52.0 Hypermetropia
0.666 0.334 0.000
N18.5 Chronic kidney disease, stage 5
0.665 0.335 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.665 0.335 0.000
M35.8 Other specified systemic involvement of connective tissue
0.665 0.335 0.000
M35.7 Hypermobility syndrome
0.665 0.335 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.665 0.335 0.000
M35.5 Multifocal fibrosclerosis
0.665 0.335 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.665 0.335 0.000
M35.2 Behcet's disease
0.665 0.335 0.000
M35.1 Other overlap syndromes
0.665 0.335 0.000
M23.9 Internal derangement of knee, unspecified
0.665 0.335 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.665 0.335 0.000
M23.4 Loose body in knee
0.665 0.335 0.000
M23.1 Discoid meniscus (congenital)
0.665 0.335 0.000
M23.0 Cystic meniscus
0.665 0.335 0.000
E14 Unspecified diabetes mellitus
0.664 0.335 0.000
N25-N29 Other disorders of kidney and ureter
0.664 0.336 0.000
R47 Speech disturbances, not elsewhere classified
0.664 0.336 0.000
O85-O92 Complications predominantly related to the puerperium
0.663 0.337 0.000
N30.2 Other chronic cystitis
0.662 0.338 0.000
M16.0 Primary coxarthrosis, bilateral
0.662 0.338 0.000
C54 Malignant neoplasm of corpus uteri
0.662 0.338 0.000
I69 Sequelae of cerebrovascular disease
0.661 0.339 0.000
Z71.9 Counselling, unspecified
0.660 0.340 0.000
M80-M85 Disorders of bone density and structure
0.660 0.340 0.000
I25.3 Aneurysm of heart
0.660 0.340 0.000
E20-E35 Disorders of other endocrine glands
0.660 0.340 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.660 0.340 0.000
N84 Polyp of female genital tract
0.659 0.341 0.000
T98 Sequelae of other and unspecified effects of external causes
0.659 0.341 0.000
T95 Sequelae of burns, corrosions and frostbite
0.659 0.341 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.659 0.341 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.659 0.341 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.659 0.341 0.000
S27.2 Traumatic heamopneumothorax
0.659 0.341 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.659 0.341 0.000
O36 Maternal care for other known or suspected foetal problems
0.658 0.342 0.000
R25.2 Cramp and spasm
0.657 0.343 0.000
F41.2 Mixed anxiety and depressive disorder
0.657 0.343 0.000
H50 Other strabismus
0.656 0.344 0.000
O47 False labour
0.655 0.345 0.000
E50-E64 Other nutritional deficiencies
0.654 0.346 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.654 0.346 0.000
N13.8 Other obstructive and reflux uropathy
0.654 0.346 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.654 0.346 0.000
N13.6 Pyonephrosis
0.654 0.346 0.000
N13.4 Hydroureter
0.654 0.346 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.654 0.346 0.000
N39.2 Orthostatic proteinuria, unspecified
0.653 0.346 0.000
N39.1 Persistent proteinuria, unspecified
0.653 0.346 0.000
R73 Elevated blood glucose level
0.653 0.346 0.000
E00-E07 Disorders of thyroid gland
0.653 0.347 0.000
T51.0 Ethanol
0.653 0.347 0.000
Z40 Prophylactic surgery
0.653 0.347 0.000
S02.1 Fracture of base of skull
0.651 0.349 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.651 0.349 0.000
C64-C68 Malignant neoplasms of urinary tract
0.651 0.349 0.000
H33 Retinal detachments and breaks
0.651 0.349 0.000
E40-E46 Malnutrition
0.650 0.349 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.650 0.350 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.650 0.350 0.000
Z29 Need for other prophylactic measures
0.650 0.350 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.649 0.351 0.000
N00-N08 Glomerular diseases
0.648 0.351 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.648 0.352 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.648 0.352 0.000
N85.7 Haematometra
0.648 0.352 0.000
N85.6 Intra-uterine synechiae
0.648 0.352 0.000
N85.5 Inversion of uterus
0.648 0.352 0.000
N85.3 Subinvolution of uterus
0.648 0.352 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.648 0.352 0.000
H31 Other disorders of choroid
0.648 0.352 0.000
H30 Chorioretinal inflammation
0.648 0.352 0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified
0.648 0.352 0.000
M25.8 Other specified joint disorders
0.647 0.353 0.000
N21 Calculus of lower urinary tract
0.647 0.353 0.000
H35.9 Retinal disorder, unspecified
0.646 0.354 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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