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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78346601
log Bayes Factor = 13.2849
Chromosome 18   position 54,574,972  (GRCh37) Explore rs78346601 on Ensembl!
Variant rs78346601 is part of Cluster X0020

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
C79 Secondary malignant neoplasm of other sites
0.998 0.002 0.000
I50 Heart failure
0.997 0.003 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.992 0.008 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.986 0.014 0.000
M05-M14 Inflammatory polyarthropathies
0.985 0.015 0.000
I50.0 Congestive heart failure
0.982 0.018 0.000
Chapter I Certain infectious and parasitic diseases
0.981 0.019 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.981 0.019 0.000
M06 Other rheumatoid arthritis
0.978 0.022 0.000
I20-I25 Ischaemic heart diseases
0.977 0.023 0.000
M06.9 Rheumatoid arthritis, unspecified
0.973 0.027 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.972 0.028 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.969 0.031 0.000
C34 Malignant neoplasm of bronchus and lung
0.967 0.033 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.960 0.040 0.000
I20 Angina pectoris
0.958 0.042 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.956 0.044 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.954 0.046 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.948 0.052 0.000
I20.0 Unstable angina
0.947 0.053 0.000
L82 Seborrhoeic keratosis
0.946 0.054 0.000
I73 Other peripheral vascular diseases
0.941 0.059 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.940 0.060 0.000
C34.9 Bronchus or lung, unspecified
0.938 0.062 0.000
Chapter XX External causes of morbidity and mortality
0.937 0.063 0.000
C64-C68 Malignant neoplasms of urinary tract
0.936 0.064 0.000
I34 Nonrheumatic mitral valve disorders
0.931 0.069 0.000
Chapter X Diseases of the respiratory system
0.931 0.069 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.930 0.070 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.928 0.072 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.924 0.076 0.000
C67 Malignant neoplasm of bladder
0.914 0.086 0.000
S00-S09 Injuries to the head
0.905 0.095 0.000
B95-B98 Bacterial, viral and other infectious agents
0.903 0.097 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.902 0.098 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.900 0.100 0.000
I80 Phlebitis and thrombophlebitis
0.900 0.100 0.000
O60-O75 Complications of labour and delivery
0.900 0.100 0.000
M10 Gout
0.899 0.101 0.000
I49 Other cardiac arrhythmias
0.899 0.101 0.000
I42 Cardiomyopathy
0.898 0.102 0.000
T81 Complications of procedures, not elsewhere classified
0.897 0.103 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.894 0.106 0.000
I50.9 Heart failure, unspecified
0.891 0.109 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.889 0.111 0.000
I24 Other acute ischaemic heart diseases
0.889 0.111 0.000
I73.9 Peripheral vascular disease, unspecified
0.887 0.113 0.000
I50.1 Left ventricular failure
0.884 0.116 0.000
C79.2 Secondary malignant neoplasm of skin
0.876 0.124 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.872 0.128 0.000
A30-A49 Other bacterial diseases
0.865 0.135 0.000
I77 Other disorders of arteries and arterioles
0.864 0.136 0.000
S02 Fracture of skull and facial bones
0.860 0.140 0.000
C34.3 Lower lobe, bronchus or lung
0.860 0.140 0.000
C67.9 Bladder, unspecified
0.859 0.141 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.859 0.141 0.000
M13 Other arthritis
0.859 0.141 0.000
C78.0 Secondary malignant neoplasm of lung
0.859 0.141 0.000
C50-C50 Malignant neoplasm of breast
0.856 0.144 0.000
Chapter XXII Codes for special purposes
0.853 0.147 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.849 0.151 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.848 0.152 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.844 0.156 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.843 0.157 0.000
I60-I69 Cerebrovascular diseases
0.839 0.161 0.000
M10.9 Gout, unspecified
0.837 0.163 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.836 0.164 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.834 0.166 0.000
J40-J47 Chronic lower respiratory diseases
0.834 0.166 0.000
I34.0 Mitral (valve) insufficiency
0.831 0.169 0.000
I73.0 Raynaud's syndrome
0.831 0.169 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.830 0.170 0.000
B35-B49 Mycoses
0.828 0.172 0.000
J09-J18 Influenza and pneumonia
0.827 0.173 0.000
L50-L54 Urticaria and erythema
0.826 0.174 0.000
M86-M90 Other osteopathies
0.818 0.181 0.000
T93 Sequelae of injuries of lower limb
0.816 0.184 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.813 0.187 0.000
S80-S89 Injuries to the knee and lower leg
0.810 0.190 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.808 0.192 0.000
T17 Foreign body in respiratory tract
0.807 0.193 0.000
M07 Psoriatic and enteropathic arthropathies
0.807 0.193 0.000
T79-T79 Certain early complications of trauma
0.807 0.193 0.000
M10.99 Gout, unspecified (Site unspecified)
0.806 0.194 0.000
I20.8 Other forms of angina pectoris
0.805 0.195 0.000
I51 Complications and ill-defined descriptions of heart disease
0.805 0.195 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.804 0.196 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.803 0.197 0.000
I34.1 Mitral (valve) prolapse
0.803 0.197 0.000
S10-S19 Injuries to the neck
0.802 0.198 0.000
L40-L45 Papulosquamous disorders
0.800 0.200 0.000
C77.5 Intrapelvic lymph nodes
0.799 0.201 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.797 0.203 0.000
S40-S49 Injuries to the shoulder and upper arm
0.795 0.205 0.000
I42.0 Dilated cardiomyopathy
0.795 0.205 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.795 0.205 0.000
J44 Other chronic obstructive pulmonary disease
0.794 0.206 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.793 0.207 0.000
Chapter VIII Diseases of the ear and mastoid process
0.792 0.208 0.000
A41 Other septicaemia
0.787 0.213 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.785 0.215 0.000
I70 Atherosclerosis
0.783 0.217 0.000
S50-S59 Injuries to the elbow and forearm
0.782 0.218 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.782 0.218 0.000
C79.6 Secondary malignant neoplasm of ovary
0.780 0.220 0.000
M13.9 Arthritis, unspecified
0.779 0.221 0.000
J90-J94 Other diseases of pleura
0.779 0.221 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.779 0.221 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.778 0.222 0.000
I27 Other pulmonary heart diseases
0.775 0.225 0.000
I49.9 Cardiac arrhythmia, unspecified
0.775 0.225 0.000
A00-A09 Intestinal infectious diseases
0.774 0.226 0.000
B25-B34 Other viral diseases
0.773 0.227 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.772 0.228 0.000
I30 Acute pericarditis
0.772 0.228 0.000
T92 Sequelae of injuries of upper limb
0.771 0.229 0.000
C78.7 Secondary malignant neoplasm of liver
0.768 0.232 0.000
I89.0 Lymphoedema, not elsewhere classified
0.764 0.236 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.762 0.238 0.000
S02.4 Fracture of malar and maxillary bones
0.761 0.239 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.761 0.239 0.000
Y95 Nosocomial condition
0.760 0.240 0.000
I87 Other disorders of veins
0.759 0.241 0.000
V40-V49 Car occupant injured in transport accident
0.757 0.243 0.000
I26 Pulmonary embolism
0.754 0.246 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.754 0.246 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.754 0.246 0.000
C50 Malignant neoplasm of breast
0.754 0.246 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.753 0.247 0.000
I38 Endocarditis, valve unspecified
0.753 0.247 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.752 0.248 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.751 0.249 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.751 0.249 0.000
I47 Paroxysmal tachycardia
0.751 0.249 0.000
D46 Myelodysplastic syndromes
0.748 0.252 0.000
X60-X84 Intentional self-harm
0.747 0.253 0.000
Chapter XXI Factors influencing health status and contact with health services
0.746 0.254 0.000
B15-B19 Viral hepatitis
0.746 0.254 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.743 0.257 0.000
W00-W19 Falls
0.742 0.258 0.000
L91 Hypertrophic disorders of skin
0.742 0.258 0.000
C67.2 Lateral wall of bladder
0.742 0.258 0.000
M91-M94 Chondropathies
0.740 0.260 0.000
M60-M63 Disorders of muscles
0.739 0.261 0.000
I49.4 Other and unspecified premature depolarisation
0.739 0.261 0.000
I05-I09 Chronic rheumatic heart diseases
0.739 0.261 0.000
M65-M68 Disorders of synovium and tendon
0.738 0.262 0.000
C34.0 Main bronchus
0.738 0.262 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.737 0.263 0.000
D48.1 Connective and other soft tissue
0.736 0.264 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.736 0.264 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.736 0.264 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.735 0.265 0.000
S60-S69 Injuries to the wrist and hand
0.735 0.265 0.000
B99-B99 Other infectious diseases
0.734 0.266 0.000
I49.5 Sick sinus syndrome
0.733 0.267 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.733 0.267 0.000
I69 Sequelae of cerebrovascular disease
0.733 0.267 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.732 0.268 0.000
I60 Subarachnoid haemorrhage
0.731 0.269 0.000
B37 Candidiasis
0.731 0.269 0.000
Z72 Problems related to lifestyle
0.728 0.272 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.728 0.272 0.000
A41.9 Septicaemia, unspecified
0.727 0.273 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.727 0.273 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.727 0.273 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.726 0.274 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.725 0.274 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.725 0.275 0.000
C50.4 Upper-outer quadrant of breast
0.725 0.275 0.000
T17.2 Foreign body in pharynx
0.724 0.276 0.000
I45 Other conduction disorders
0.724 0.276 0.000
O62 Abnormalities of forces of labour
0.724 0.276 0.000
J42 Unspecified chronic bronchitis
0.723 0.277 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.721 0.279 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.721 0.279 0.000
V80-V89 Other land transport accidents
0.719 0.281 0.000
M20-M25 Other joint disorders
0.719 0.281 0.000
H80-H83 Diseases of inner ear
0.719 0.281 0.000
S80 Superficial injury of lower leg
0.718 0.282 0.000
C77.1 Intrathoracic lymph nodes
0.718 0.282 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.717 0.282 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.717 0.283 0.000
C67.4 Posterior wall of bladder
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
S90-S99 Injuries to the ankle and foot
0.717 0.283 0.000
T18 Foreign body in alimentary tract
0.717 0.283 0.000
S02.2 Fracture of nasal bones
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
O80-O84 Delivery
0.716 0.284 0.000
I77.1 Stricture of artery
0.716 0.284 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.716 0.284 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.716 0.284 0.000
L40 Psoriasis
0.715 0.285 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.715 0.285 0.000
M00-M03 Infectious arthropathies
0.714 0.285 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.714 0.286 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.714 0.286 0.000
J11 Influenza, virus not identified
0.713 0.287 0.000
I22 Subsequent myocardial infarction
0.712 0.288 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.711 0.289 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.710 0.290 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.710 0.290 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.710 0.290 0.000
I72 Other aneurysm
0.709 0.291 0.000
M14 Arthropathies in other diseases classified elsewhere
0.706 0.293 0.000
M12 Other specific arthropathies
0.706 0.293 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.706 0.293 0.000
M08 Juvenile arthritis
0.706 0.293 0.000
W20-W49 Exposure to inanimate mechanical forces
0.706 0.293 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.706 0.294 0.000
C67.5 Bladder neck
0.705 0.295 0.000
O75.8 Other specified complications of labour and delivery
0.705 0.295 0.000
C67.1 Dome of bladder
0.705 0.295 0.000
M06.0 Seronegative rheumatoid arthritis
0.704 0.296 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.704 0.296 0.000
Z72.1 Alcohol use
0.704 0.296 0.000
L53 Other erythematous conditions
0.704 0.296 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.703 0.296 0.000
B65-B83 Helminthiases
0.703 0.296 0.000
B50-B64 Protozoal diseases
0.703 0.296 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.703 0.296 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.703 0.296 0.000
A75-A79 Rickettsioses
0.703 0.296 0.000
A70-A74 Other diseases caused by chlamydiae
0.703 0.296 0.000
A65-A69 Other spirochaetal diseases
0.703 0.296 0.000
A20-A28 Certain zoonotic bacterial diseases
0.703 0.296 0.000
A15-A19 Tuberculosis
0.703 0.296 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.703 0.297 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.703 0.297 0.000
C32 Malignant neoplasm of larynx
0.703 0.297 0.000
C31 Malignant neoplasm of accessory sinuses
0.703 0.297 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.703 0.297 0.000
C37 Malignant neoplasm of thymus
0.703 0.297 0.000
C33 Malignant neoplasm of trachea
0.703 0.297 0.000
A80-A89 Viral infections of the central nervous system
0.702 0.297 0.000
I42.8 Other cardiomyopathies
0.702 0.298 0.000
M06.8 Other specified rheumatoid arthritis
0.701 0.299 0.000
M06.4 Inflammatory polyarthropathy
0.701 0.299 0.000
M06.3 Rheumatoid nodule
0.701 0.299 0.000
M06.2 Rheumatoid bursitis
0.701 0.299 0.000
M06.1 Adult-onset Still's disease
0.701 0.299 0.000
I23 Certain current complications following acute myocardial infarction
0.701 0.299 0.000
M11 Other crystal arthropathies
0.700 0.300 0.000
J60-J70 Lung diseases due to external agents
0.700 0.300 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.698 0.302 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.698 0.302 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.698 0.302 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.698 0.302 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.698 0.302 0.000
J00-J06 Acute upper respiratory infections
0.698 0.302 0.000
S02.3 Fracture of orbital floor
0.697 0.303 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.697 0.303 0.000
S06 Intracranial injury
0.697 0.303 0.000
C77.8 Lymph nodes of multiple regions
0.696 0.304 0.000
I77.8 Other specified disorders of arteries and arterioles
0.695 0.305 0.000
M23 Internal derangement of knee
0.694 0.306 0.000
C34.8 Overlapping lesion of bronchus and lung
0.694 0.306 0.000
C34.2 Middle lobe, bronchus or lung
0.694 0.306 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.693 0.307 0.000
V10-V19 Pedal cyclist injured in transport accident
0.693 0.307 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.693 0.307 0.000
C34.1 Upper lobe, bronchus or lung
0.691 0.309 0.000
T91 Sequelae of injuries of neck and trunk
0.690 0.310 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.690 0.310 0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.690 0.310 0.000
I95 Hypotension
0.689 0.311 0.000
L10-L14 Bullous disorders
0.688 0.312 0.000
C67.6 Ureteric orifice
0.688 0.312 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.687 0.313 0.000
M05 Seropositive rheumatoid arthritis
0.686 0.314 0.000
I49.1 Atrial premature depolarisation
0.686 0.314 0.000
O85-O92 Complications predominantly related to the puerperium
0.685 0.315 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.685 0.315 0.000
T87 Complications peculiar to reattachment and amputation
0.684 0.316 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.684 0.316 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.684 0.316 0.000
M40-M43 Deforming dorsopathies
0.683 0.317 0.000
I51.9 Heart disease, unspecified
0.681 0.319 0.000
T86 Failure and rejection of transplanted organs and tissues
0.680 0.319 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.681 0.319 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.680 0.320 0.000
S00 Superficial injury of head
0.680 0.320 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.680 0.320 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.680 0.320 0.000
L94 Other localised connective tissue disorders
0.680 0.320 0.000
L93 Lupus erythematosus
0.680 0.320 0.000
L87 Transepidermal elimination disorders
0.680 0.320 0.000
L88 Pyoderma gangrenosum
0.680 0.320 0.000
L86 Keratoderma in diseases classified elsewhere
0.680 0.320 0.000
L83 Acanthosis nigricans
0.680 0.320 0.000
L80 Vitiligo
0.680 0.320 0.000
M07.3 Other psoriatic arthropathies
0.679 0.321 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.679 0.321 0.000
I74 Arterial embolism and thrombosis
0.678 0.322 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.677 0.323 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.677 0.323 0.000
L89 Decubitus ulcer
0.677 0.323 0.000
I27.0 Primary pulmonary hypertension
0.677 0.323 0.000
T90 Sequelae of injuries of head
0.676 0.324 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.676 0.324 0.000
Z72.0 Tobacco use
0.676 0.324 0.000
I73.8 Other specified peripheral vascular diseases
0.674 0.325 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.674 0.325 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.674 0.326 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.674 0.326 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.674 0.326 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.674 0.326 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.674 0.326 0.000
D48.7 Other specified sites
0.674 0.326 0.000
O66 Other obstructed labour
0.673 0.327 0.000
M45-M49 Spondylopathies
0.673 0.327 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.673 0.327 0.000
I24.8 Other forms of acute ischaemic heart disease
0.672 0.328 0.000
I51.0 Cardiac septal defect, acquired
0.672 0.328 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.672 0.328 0.000
Y35-Y36 Legal intervention and operations of war
0.672 0.328 0.000
Y10-Y34 Event of undetermined intent
0.672 0.328 0.000
Y00-Y09 Assault
0.672 0.328 0.000
X85-X99 Assault
0.672 0.328 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.672 0.328 0.000
X50-X57 Overexertion, travel and privation
0.672 0.328 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.672 0.328 0.000
X30-X39 Exposure to forces of nature
0.672 0.328 0.000
X20-X29 Contact with venomous animals and plants
0.672 0.328 0.000
X10-X19 Contact with heat and hot substances
0.672 0.328 0.000
X00-X09 Exposure to smoke, fire and flames
0.672 0.328 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.672 0.328 0.000
W75-W84 Other accidental threats to breathing
0.672 0.328 0.000
W65-W74 Accidental drowning and submersion
0.672 0.328 0.000
W50-W64 Exposure to animate mechanical forces
0.672 0.328 0.000
V98-V99 Other and unspecified transport accidents
0.672 0.328 0.000
V95-V97 Air and space transport accidents
0.672 0.328 0.000
V90-V94 Water transport accidents
0.672 0.328 0.000
V70-V79 Bus occupant injured in transport accident
0.672 0.328 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.672 0.328 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.672 0.328 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.672 0.328 0.000
V01-V09 Pedestrian injured in transport accident
0.672 0.328 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.671 0.328 0.000
C77.3 Axillary and upper limb lymph nodes
0.671 0.329 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.671 0.329 0.000
I33 Acute and subacute endocarditis
0.671 0.329 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.671 0.329 0.000
C66 Malignant neoplasm of ureter
0.671 0.329 0.000
C65 Malignant neoplasm of renal pelvis
0.671 0.329 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.671 0.329 0.000
J14 Pneumonia due to Haemophilus influenzae
0.670 0.330 0.000
D45 Polycythaemia vera
0.669 0.331 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.669 0.331 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.668 0.332 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.668 0.332 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.668 0.332 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.668 0.332 0.000
C80 Malignant neoplasm without specification of site
0.667 0.332 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.667 0.333 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.667 0.333 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.667 0.333 0.000
I42.9 Cardiomyopathy, unspecified
0.666 0.333 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.666 0.334 0.000
I88 Nonspecific lymphadenitis
0.666 0.334 0.000
I81 Portal vein thrombosis
0.666 0.334 0.000
S02.8 Fractures of other skull and facial bones
0.663 0.337 0.000
T98 Sequelae of other and unspecified effects of external causes
0.663 0.337 0.000
T95 Sequelae of burns, corrosions and frostbite
0.663 0.337 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.663 0.337 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.663 0.337 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.663 0.337 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.660 0.340 0.000
J92 Pleural plaque
0.660 0.340 0.000
C50.5 Lower-outer quadrant of breast
0.659 0.341 0.000
S02.0 Fracture of vault of skull
0.657 0.343 0.000
M80-M85 Disorders of bone density and structure
0.657 0.343 0.000
I46 Cardiac arrest
0.657 0.343 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.656 0.344 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.656 0.344 0.000
C67.8 Overlapping lesion of bladder
0.655 0.345 0.000
C67.7 Urachus
0.655 0.345 0.000
C67.3 Anterior wall of bladder
0.655 0.345 0.000
C67.0 Trigone of bladder
0.655 0.345 0.000
O36 Maternal care for other known or suspected foetal problems
0.654 0.346 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.653 0.347 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.652 0.348 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.650 0.350 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.650 0.350 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.650 0.350 0.000
V20-V29 Motorcycle rider injured in transport accident
0.649 0.351 0.000
S08 Traumatic amputation of part of head
0.649 0.351 0.000
S07 Crushing injury of head
0.649 0.351 0.000
S05 Injury of eye and orbit
0.649 0.351 0.000
S04 Injury of cranial nerves
0.649 0.351 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.649 0.351 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.648 0.352 0.000
I20.1 Angina pectoris with documented spasm
0.647 0.353 0.000
S86 Injury of muscle and tendon at lower leg level
0.647 0.353 0.000
T19 Foreign body in genito-urinary tract
0.647 0.353 0.000
T15 Foreign body on external eye
0.647 0.353 0.000
T16 Foreign body in ear
0.647 0.353 0.000
S09 Other and unspecified injuries of head
0.647 0.353 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.646 0.353 0.000
M87 Osteonecrosis
0.646 0.354 0.000
T14 Injury of unspecified body region
0.646 0.354 0.000
J84 Other interstitial pulmonary diseases
0.646 0.354 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.646 0.354 0.000
S40 Superficial injury of shoulder and upper arm
0.646 0.354 0.000
I28 Other diseases of pulmonary vessels
0.645 0.355 0.000
O74 Complications of anaesthesia during labour and delivery
0.645 0.355 0.000
O71 Other obstetric trauma
0.645 0.355 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.645 0.355 0.000
O61 Failed induction of labour
0.645 0.355 0.000
O60 Preterm delivery
0.645 0.355 0.000
M10.4 Other secondary gout
0.644 0.355 0.000
M10.3 Gout due to impairment of renal function
0.644 0.355 0.000
M10.2 Drug-induced gout
0.644 0.355 0.000
M10.1 Lead-induced gout
0.644 0.355 0.000
M10.0 Idiopathic gout
0.644 0.355 0.000
I49.2 Junctional premature depolarisation
0.644 0.356 0.000
I49.8 Other specified cardiac arrhythmias
0.644 0.356 0.000
T93.2 Sequelae of other fractures of lower limb
0.644 0.356 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.644 0.356 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.644 0.356 0.000
I42.6 Alcoholic cardiomyopathy
0.644 0.356 0.000
I42.5 Other restrictive cardiomyopathy
0.644 0.356 0.000
I42.4 Endocardial fibroelastosis
0.644 0.356 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.644 0.356 0.000
L50 Urticaria
0.644 0.356 0.000
S89 Other and unspecified injuries of lower leg
0.644 0.356 0.000
T81.9 Unspecified complication of procedure
0.643 0.357 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.643 0.357 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.643 0.357 0.000
J10 Influenza due to identified influenza virus
0.643 0.357 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.643 0.357 0.000
D47.2 Monoclonal gammopathy
0.643 0.357 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.642 0.358 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.642 0.358 0.000
C77.9 Lymph node, unspecified
0.641 0.359 0.000
I49.0 Ventricular fibrillation and flutter
0.641 0.359 0.000
I47.2 Ventricular tachycardia
0.640 0.360 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.640 0.360 0.000
S20-S29 Injuries to the thorax
0.640 0.360 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.639 0.361 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.638 0.362 0.000
M90 Osteopathies in diseases classified elsewhere
0.638 0.362 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.637 0.362 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.637 0.362 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.637 0.362 0.000
I24.1 Dressler's syndrome
0.637 0.363 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.637 0.363 0.000
I31 Other diseases of pericardium
0.636 0.363 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.636 0.364 0.000
D48.5 Skin
0.635 0.365 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.635 0.365 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.634 0.366 0.000
L85 Other epidermal thickening
0.633 0.366 0.000
I82 Other venous embolism and thrombosis
0.633 0.367 0.000
I83 Varicose veins of lower extremities
0.632 0.367 0.000
S80.8 Other superficial injuries of lower leg
0.632 0.368 0.000
L91.8 Other hypertrophic disorders of skin
0.632 0.368 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.632 0.368 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.631 0.369 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.631 0.369 0.000
Chapter XIV Diseases of the genitourinary system
0.629 0.371 0.000
D48.6 Breast
0.629 0.371 0.000
Z75 Problems related to medical facilities and other health care
0.628 0.372 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.628 0.372 0.000
I77.6 Arteritis, unspecified
0.628 0.372 0.000
B37.9 Candidiasis, unspecified
0.628 0.372 0.000
U80 Agent resistant to penicillin and related antibiotics
0.628 0.372 0.000
V48 Car occupant injured in noncollision transport accident
0.627 0.373 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.627 0.373 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.626 0.374 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.625 0.375 0.000
T66-T78 Other and unspecified effects of external causes
0.624 0.375 0.000
S51 Open wound of forearm
0.625 0.375 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.624 0.376 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.624 0.376 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.624 0.376 0.000
B34 Viral infection of unspecified site
0.623 0.377 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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