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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78378222
log Bayes Factor = 67.1003
Chromosome 17   position 7,571,752  (GRCh37) Explore rs78378222 on Ensembl!
Variant rs78378222 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
D25.9 Leiomyoma of uterus, unspecified
1.000 0.000 0.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
D25 Leiomyoma of uterus
1.000 0.000 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
1.000 0.000 0.000
D10-D36 Benign neoplasms
1.000 0.000 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
1.000 0.000 0.000
N80-N98 Noninflammatory disorders of female genital tract
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
C44.1 Skin of eyelid, including canthus
1.000 0.000 0.000
N92 Excessive, frequent and irregular menstruation
1.000 0.000 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.999 0.001 0.000
D23 Other benign neoplasms of skin
0.999 0.001 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.999 0.001 0.000
L82 Seborrhoeic keratosis
0.998 0.002 0.000
Chapter XI Diseases of the digestive system
0.998 0.002 0.000
D12.5 Sigmoid colon
0.997 0.003 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.997 0.003 0.000
K55-K64 Other diseases of intestines
0.997 0.003 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.997 0.003 0.000
D25.2 Subserosal leiomyoma of uterus
0.996 0.004 0.000
D12.8 Rectum
0.996 0.004 0.000
D22 Melanocytic naevi
0.995 0.005 0.000
K62 Other diseases of anus and rectum
0.995 0.005 0.000
D25.0 Submucous leiomyoma of uterus
0.992 0.008 0.000
K63 Other diseases of intestine
0.992 0.008 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.989 0.011 0.000
Chapter VI Diseases of the nervous system
0.988 0.012 0.000
D12.2 Ascending colon
0.986 0.014 0.000
K62.1 Rectal polyp
0.986 0.014 0.000
C44.4 Skin of scalp and neck
0.985 0.015 0.000
K63.5 Polyp of colon
0.983 0.017 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.983 0.017 0.000
C44.6 Skin of upper limb, including shoulder
0.980 0.020 0.000
L90 Atrophic disorders of skin
0.980 0.020 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.979 0.021 0.000
D27 Benign neoplasm of ovary
0.978 0.022 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.973 0.027 0.000
K62.0 Anal polyp
0.972 0.028 0.000
C71 Malignant neoplasm of brain
0.971 0.029 0.000
D12.3 Transverse colon
0.969 0.031 0.000
L90.5 Scar conditions and fibrosis of skin
0.967 0.033 0.000
C44.5 Skin of trunk
0.967 0.033 0.000
D12.6 Colon, unspecified
0.966 0.034 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.963 0.037 0.000
D25.1 Intramural leiomyoma of uterus
0.962 0.038 0.000
D12.4 Descending colon
0.957 0.043 0.000
C43 Malignant melanoma of skin
0.952 0.048 0.000
N87 Dysplasia of cervix uteri
0.951 0.049 0.000
C79 Secondary malignant neoplasm of other sites
0.951 0.049 0.000
D12.0 Caecum
0.951 0.049 0.000
G90-G99 Other disorders of the nervous system
0.951 0.049 0.000
Chapter VII Diseases of the eye and adnexa
0.940 0.060 0.000
D24 Benign neoplasm of breast
0.940 0.060 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.937 0.063 0.000
N84 Polyp of female genital tract
0.936 0.064 0.000
D36 Benign neoplasm of other and unspecified sites
0.934 0.066 0.000
G40-G47 Episodic and paroxysmal disorders
0.933 0.067 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.931 0.069 0.000
K70-K77 Diseases of liver
0.930 0.070 0.000
D23.6 Skin of upper limb, including shoulder
0.928 0.072 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.927 0.073 0.000
N80 Endometriosis
0.923 0.077 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.923 0.077 0.000
G93 Other disorders of brain
0.915 0.085 0.000
C44.2 Skin of ear and external auricular canal
0.909 0.091 0.000
D22.5 Melanocytic naevi of trunk
0.907 0.093 0.000
D23.7 Skin of lower limb, including hip
0.907 0.093 0.000
N60-N64 Disorders of breast
0.906 0.094 0.000
D17 Benign lipomatous neoplasm
0.906 0.094 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.899 0.101 0.000
S60-S69 Injuries to the wrist and hand
0.896 0.104 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.895 0.105 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.892 0.108 0.000
N83.2 Other and unspecified ovarian cysts
0.891 0.109 0.000
Chapter XXI Factors influencing health status and contact with health services
0.890 0.110 0.000
D23.5 Skin of trunk
0.890 0.110 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.889 0.111 0.000
D23.1 Skin of eyelid, including canthus
0.887 0.113 0.000
D36.1 Peripheral nerves and autonomic nervous system
0.886 0.114 0.000
C71.1 Frontal lobe
0.886 0.114 0.000
S80-S89 Injuries to the knee and lower leg
0.881 0.119 0.000
H30-H36 Disorders of choroid and retina
0.879 0.121 0.000
D23.3 Skin of other and unspecified parts of face
0.878 0.122 0.000
N83.1 Corpus luteum cyst
0.878 0.122 0.000
C44.7 Skin of lower limb, including hip
0.877 0.123 0.000
L60-L75 Disorders of skin appendages
0.876 0.124 0.000
C71.9 Brain, unspecified
0.873 0.127 0.000
K63.1 Perforation of intestine (nontraumatic)
0.873 0.127 0.000
K40-K46 Hernia
0.871 0.129 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.870 0.130 0.000
N60 Benign mammary dysplasia
0.869 0.131 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.866 0.134 0.000
K65-K67 Diseases of peritoneum
0.866 0.134 0.000
Z86 Personal history of certain other diseases
0.864 0.136 0.000
N83.0 Follicular cyst of ovary
0.863 0.137 0.000
N87.1 Moderate cervical dysplasia
0.862 0.138 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.862 0.138 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.861 0.139 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.861 0.139 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.859 0.141 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.858 0.142 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.857 0.142 0.000
Z85 Personal history of malignant neoplasm
0.855 0.145 0.000
Z86.0 Personal history of other neoplasms
0.854 0.146 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.854 0.146 0.000
C78.2 Secondary malignant neoplasm of pleura
0.852 0.148 0.000
N84.1 Polyp of cervix uteri
0.847 0.153 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.845 0.155 0.000
G43 Migraine
0.843 0.157 0.000
D18 Haemangioma and lymphangioma, any site
0.841 0.159 0.000
L20-L30 Dermatitis and eczema
0.841 0.159 0.000
Z86.4 Personal history of psychoactive substance abuse
0.841 0.159 0.000
G40 Epilepsy
0.840 0.160 0.000
N76 Other inflammation of vagina and vulva
0.840 0.160 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.839 0.161 0.000
N87.0 Mild cervical dysplasia
0.839 0.161 0.000
K62.5 Haemorrhage of anus and rectum
0.837 0.163 0.000
Chapter I Certain infectious and parasitic diseases
0.833 0.167 0.000
H35 Other retinal disorders
0.832 0.168 0.000
D32 Benign neoplasm of meninges
0.831 0.169 0.000
N73 Other female pelvic inflammatory diseases
0.830 0.170 0.000
C71.2 Temporal lobe
0.829 0.171 0.000
C92 Myeloid leukaemia
0.828 0.172 0.000
C78.0 Secondary malignant neoplasm of lung
0.827 0.173 0.000
G93.9 Disorder of brain, unspecified
0.825 0.175 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.819 0.181 0.000
K76 Other diseases of liver
0.817 0.183 0.000
C71.8 Overlapping lesion of brain
0.817 0.183 0.000
C43.5 Malignant melanoma of trunk
0.817 0.183 0.000
C44.0 Skin of lip
0.817 0.183 0.000
D22.4 Melanocytic naevi of scalp and neck
0.816 0.184 0.000
D23.9 Skin, unspecified
0.813 0.187 0.000
L91 Hypertrophic disorders of skin
0.811 0.189 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.811 0.189 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.811 0.189 0.000
H10-H13 Disorders of conjunctiva
0.808 0.192 0.000
N40-N51 Diseases of male genital organs
0.808 0.192 0.000
N25-N29 Other disorders of kidney and ureter
0.807 0.193 0.000
N86 Erosion and ectropion of cervix uteri
0.807 0.193 0.000
L89 Decubitus ulcer
0.805 0.195 0.000
N92.3 Ovulation bleeding
0.805 0.195 0.000
C64-C68 Malignant neoplasms of urinary tract
0.804 0.196 0.000
H53-H54 Visual disturbances and blindness
0.804 0.196 0.000
K42 Umbilical hernia
0.802 0.198 0.000
D12.9 Anus and anal canal
0.801 0.199 0.000
R47-R49 Symptoms and signs involving speech and voice
0.800 0.200 0.000
N84.0 Polyp of corpus uteri
0.800 0.200 0.000
K55 Vascular disorders of intestine
0.797 0.203 0.000
N93 Other abnormal uterine and vaginal bleeding
0.796 0.204 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.792 0.208 0.000
M20-M25 Other joint disorders
0.791 0.209 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.790 0.210 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.787 0.213 0.000
D23.2 Skin of ear and external auricular canal
0.785 0.214 0.000
N80.1 Endometriosis of ovary
0.785 0.215 0.000
C80 Malignant neoplasm without specification of site
0.784 0.216 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.784 0.216 0.000
K75 Other inflammatory liver diseases
0.782 0.218 0.000
G91 Hydrocephalus
0.782 0.218 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.780 0.220 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.779 0.221 0.000
Chapter XXII Codes for special purposes
0.779 0.221 0.000
L85 Other epidermal thickening
0.777 0.223 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.776 0.224 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.775 0.225 0.000
G93.8 Other specified disorders of brain
0.774 0.226 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.772 0.228 0.000
D33.3 Cranial nerves
0.770 0.230 0.000
T66-T78 Other and unspecified effects of external causes
0.769 0.231 0.000
K63.9 Disease of intestine, unspecified
0.767 0.233 0.000
N70 Salpingitis and oophoritis
0.766 0.234 0.000
R47 Speech disturbances, not elsewhere classified
0.765 0.235 0.000
N99-N99 Other disorders of the genitourinary system
0.765 0.235 0.000
K74 Fibrosis and cirrhosis of liver
0.763 0.237 0.000
G40.9 Epilepsy, unspecified
0.763 0.237 0.000
C91 Lymphoid leukaemia
0.761 0.239 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.760 0.240 0.000
D11 Benign neoplasm of major salivary glands
0.760 0.240 0.000
Chapter VIII Diseases of the ear and mastoid process
0.760 0.240 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.759 0.241 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.757 0.243 0.000
G47 Sleep disorders
0.756 0.244 0.000
N92.4 Excessive bleeding in the premenopausal period
0.756 0.244 0.000
N80.0 Endometriosis of uterus
0.755 0.245 0.000
K62.4 Stenosis of anus and rectum
0.755 0.245 0.000
K43 Ventral hernia
0.754 0.246 0.000
D10 Benign neoplasm of mouth and pharynx
0.754 0.246 0.000
N60.8 Other benign mammary dysplasias
0.753 0.247 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.752 0.248 0.000
G70-G73 Diseases of myoneural junction and muscle
0.752 0.248 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.752 0.248 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.752 0.248 0.000
S62 Fracture at wrist and hand level
0.750 0.250 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.749 0.251 0.000
H35.3 Degeneration of macula and posterior pole
0.749 0.251 0.000
L40-L45 Papulosquamous disorders
0.749 0.251 0.000
K76.8 Other specified diseases of liver
0.749 0.251 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.748 0.252 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.748 0.252 0.000
K63.2 Fistula of intestine
0.748 0.252 0.000
N60.3 Fibrosclerosis of breast
0.747 0.253 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.746 0.254 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.745 0.255 0.000
K66 Other disorders of peritoneum
0.744 0.256 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.744 0.256 0.000
N20-N23 Urolithiasis
0.742 0.258 0.000
S81 Open wound of lower leg
0.742 0.258 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.741 0.258 0.000
N80.2 Endometriosis of Fallopian tube
0.741 0.259 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.741 0.259 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.740 0.260 0.000
D35.1 Parathyroid gland
0.739 0.261 0.000
C92.0 Acute myeloid leukaemia
0.739 0.261 0.000
N72 Inflammatory disease of cervix uteri
0.737 0.263 0.000
N76.2 Acute vulvitis
0.736 0.264 0.000
S68 Traumatic amputation of wrist and hand
0.734 0.266 0.000
G93.6 Cerebral oedema
0.734 0.266 0.000
G81 Hemiplegia
0.734 0.266 0.000
N73.6 Female pelvic peritoneal adhesions
0.734 0.266 0.000
L98.0 Pyogenic granuloma
0.734 0.266 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.734 0.266 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.733 0.267 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.733 0.267 0.000
C79.2 Secondary malignant neoplasm of skin
0.732 0.268 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.731 0.269 0.000
G43.9 Migraine, unspecified
0.731 0.269 0.000
N63 Unspecified lump in breast
0.730 0.270 0.000
K60 Fissure and fistula of anal and rectal regions
0.730 0.270 0.000
L29 Pruritus
0.729 0.271 0.000
D18.0 Haemangioma, any site
0.728 0.272 0.000
L03 Cellulitis
0.727 0.273 0.000
L72.0 Epidermal cyst
0.727 0.273 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.724 0.276 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.723 0.277 0.000
L50-L54 Urticaria and erythema
0.723 0.277 0.000
D12.7 Rectosigmoid junction
0.722 0.278 0.000
G93.3 Postviral fatigue syndrome
0.722 0.278 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.719 0.281 0.000
D45 Polycythaemia vera
0.717 0.283 0.000
Chapter V Mental and behavioural disorders
0.717 0.283 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.717 0.283 0.000
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
D12.1 Appendix
0.717 0.283 0.000
D31 Benign neoplasm of eye and adnexa
0.717 0.283 0.000
D30 Benign neoplasm of urinary organs
0.717 0.283 0.000
D29 Benign neoplasm of male genital organs
0.717 0.283 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.717 0.283 0.000
D26 Other benign neoplasms of uterus
0.717 0.283 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.717 0.283 0.000
D19 Benign neoplasm of mesothelial tissue
0.717 0.283 0.000
D16 Benign neoplasm of bone and articular cartilage
0.717 0.283 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.717 0.283 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.717 0.283 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.717 0.283 0.000
L94 Other localised connective tissue disorders
0.717 0.283 0.000
L93 Lupus erythematosus
0.717 0.283 0.000
L87 Transepidermal elimination disorders
0.717 0.283 0.000
L88 Pyoderma gangrenosum
0.717 0.283 0.000
L86 Keratoderma in diseases classified elsewhere
0.717 0.283 0.000
L84 Corns and callosities
0.717 0.283 0.000
L83 Acanthosis nigricans
0.717 0.283 0.000
L80 Vitiligo
0.717 0.283 0.000
N98 Complications associated with artificial fertilisation
0.717 0.283 0.000
N91 Absent, scanty and rare menstruation
0.717 0.283 0.000
N82 Fistulae involving female genital tract
0.717 0.283 0.000
N96 Habitual aborter
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
L10-L14 Bullous disorders
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
N92.5 Other specified irregular menstruation
0.717 0.283 0.000
N92.2 Excessive menstruation at puberty
0.717 0.283 0.000
D23.4 Skin of scalp and neck
0.716 0.284 0.000
D23.0 Skin of lip
0.716 0.284 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.716 0.284 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.716 0.284 0.000
L98.5 Mucinosis of skin
0.716 0.284 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.716 0.284 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.716 0.284 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.716 0.284 0.000
L98.1 Factitial dermatitis
0.716 0.284 0.000
D00-D09 In situ neoplasms
0.716 0.284 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.716 0.284 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.715 0.285 0.000
N83.7 Haematoma of broad ligament
0.715 0.285 0.000
N83.6 Haematosalpinx
0.715 0.285 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.715 0.285 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.715 0.285 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.715 0.285 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.715 0.285 0.000
H53 Visual disturbances
0.715 0.285 0.000
K90-K93 Other diseases of the digestive system
0.715 0.285 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.714 0.286 0.000
D22.9 Melanocytic naevi, unspecified
0.713 0.287 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.713 0.287 0.000
D22.0 Melanocytic naevi of lip
0.713 0.287 0.000
K62.7 Radiation proctitis
0.713 0.287 0.000
K62.2 Anal prolapse
0.713 0.287 0.000
H11 Other disorders of conjunctiva
0.713 0.287 0.000
K63.4 Enteroptosis
0.711 0.289 0.000
K63.0 Abscess of intestine
0.711 0.289 0.000
B95-B98 Bacterial, viral and other infectious agents
0.711 0.289 0.000
L72.1 Trichilemmal cyst
0.711 0.289 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.709 0.290 0.000
Z90.7 Acquired absence of genital organ(s)
0.709 0.291 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.709 0.291 0.000
R21 Rash and other nonspecific skin eruption
0.708 0.292 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.708 0.292 0.000
D50-D53 Nutritional anaemias
0.708 0.292 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.706 0.294 0.000
S20-S29 Injuries to the thorax
0.706 0.294 0.000
H43-H45 Disorders of vitreous body and globe
0.705 0.295 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.705 0.295 0.000
C70 Malignant neoplasm of meninges
0.705 0.295 0.000
C69 Malignant neoplasm of eye and adnexa
0.705 0.295 0.000
K61 Abscess of anal and rectal regions
0.704 0.295 0.000
S90-S99 Injuries to the ankle and foot
0.704 0.296 0.000
N60.0 Solitary cyst of breast
0.703 0.297 0.000
L90.9 Atrophic disorder of skin, unspecified
0.703 0.297 0.000
L90.8 Other atrophic disorders of skin
0.703 0.297 0.000
L90.6 Striae atrophicae
0.703 0.297 0.000
L90.4 Acrodermatitis chronica atrophicans
0.703 0.297 0.000
L90.3 Atrophoderma of Pasini and Pierini
0.703 0.297 0.000
L90.2 Anetoderma of Jadassohn-Pellizzari
0.703 0.297 0.000
L90.1 Anetoderma of Schweninger-Buzzi
0.703 0.297 0.000
T79-T79 Certain early complications of trauma
0.702 0.298 0.000
S70-S79 Injuries to the hip and thigh
0.702 0.298 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.702 0.298 0.000
T33-T35 Frostbite
0.702 0.298 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.702 0.298 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.702 0.298 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.702 0.298 0.000
T00-T07 Injuries involving multiple body regions
0.702 0.298 0.000
S10-S19 Injuries to the neck
0.702 0.298 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.700 0.300 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.698 0.301 0.000
G43.8 Other migraine
0.698 0.301 0.000
N43 Hydrocele and spermatocele
0.698 0.302 0.000
M23 Internal derangement of knee
0.698 0.302 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.697 0.303 0.000
L81 Other disorders of pigmentation
0.696 0.304 0.000
C71.7 Brain stem
0.696 0.304 0.000
C71.6 Cerebellum
0.696 0.304 0.000
C71.5 Cerebral ventricle
0.696 0.304 0.000
C71.4 Occipital lobe
0.696 0.304 0.000
C71.3 Parietal lobe
0.696 0.304 0.000
C71.0 Cerebrum, except lobes and ventricles
0.696 0.304 0.000
H55-H59 Other disorders of eye and adnexa
0.696 0.304 0.000
N75 Diseases of Bartholin's gland
0.696 0.304 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.695 0.305 0.000
Z86.7 Personal history of diseases of the circulatory system
0.694 0.306 0.000
M80-M85 Disorders of bone density and structure
0.693 0.306 0.000
N60.1 Diffuse cystic mastopathy
0.693 0.307 0.000
H33 Retinal detachments and breaks
0.691 0.308 0.000
C60-C63 Malignant neoplasms of male genital organs
0.691 0.309 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.691 0.309 0.000
K63.3 Ulcer of intestine
0.691 0.309 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.690 0.309 0.000
N71 Inflammatory disease of uterus, except cervix
0.690 0.309 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.690 0.310 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.688 0.311 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.688 0.312 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.688 0.312 0.000
C81 Hodgkin's disease
0.687 0.312 0.000
H34 Retinal vascular occlusions
0.687 0.313 0.000
L05 Pilonidal cyst
0.687 0.313 0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck
0.687 0.313 0.000
G20-G26 Extrapyramidal and movement disorders
0.685 0.315 0.000
N80.9 Endometriosis, unspecified
0.685 0.315 0.000
S89 Other and unspecified injuries of lower leg
0.684 0.315 0.000
N80.8 Other endometriosis
0.684 0.316 0.000
C50-C50 Malignant neoplasm of breast
0.683 0.316 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.683 0.317 0.000
Chapter XX External causes of morbidity and mortality
0.683 0.317 0.000
R47.0 Dysphasia and aphasia
0.683 0.317 0.000
M50-M54 Other dorsopathies
0.682 0.318 0.000
C43.9 Malignant melanoma of skin, unspecified
0.682 0.318 0.000
C43.8 Overlapping malignant melanoma of skin
0.682 0.318 0.000
C43.4 Malignant melanoma of scalp and neck
0.682 0.318 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.682 0.318 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.682 0.318 0.000
C43.0 Malignant melanoma of lip
0.682 0.318 0.000
N87.2 Severe cervical dysplasia, not elsewhere classified
0.682 0.318 0.000
C79.6 Secondary malignant neoplasm of ovary
0.682 0.318 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.682 0.318 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.682 0.318 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.682 0.318 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.682 0.318 0.000
G96 Other disorders of central nervous system
0.682 0.318 0.000
G95 Other diseases of spinal cord
0.682 0.318 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.682 0.318 0.000
G90 Disorders of autonomic nervous system
0.682 0.318 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.682 0.318 0.000
G92 Toxic encephalopathy
0.682 0.318 0.000
S60 Superficial injury of wrist and hand
0.682 0.318 0.000
M05-M14 Inflammatory polyarthropathies
0.681 0.319 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.680 0.320 0.000
D34 Benign neoplasm of thyroid gland
0.680 0.320 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.680 0.320 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.680 0.320 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.679 0.320 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.678 0.322 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.678 0.322 0.000
Z93 Artificial opening status
0.678 0.322 0.000
H35.9 Retinal disorder, unspecified
0.677 0.323 0.000
R30-R39 Symptoms and signs involving the urinary system
0.676 0.324 0.000
K65 Peritonitis
0.676 0.324 0.000
D32.9 Meninges, unspecified
0.675 0.325 0.000
S32 Fracture of lumbar spine and pelvis
0.675 0.325 0.000
D13.1 Stomach
0.675 0.325 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.674 0.326 0.000
H35.0 Background retinopathy and retinal vascular changes
0.673 0.327 0.000
L91.0 Keloid scar
0.673 0.327 0.000
G82 Paraplegia and tetraplegia
0.673 0.327 0.000
R47.8 Other and unspecified speech disturbances
0.673 0.327 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.672 0.328 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.672 0.328 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.672 0.328 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.672 0.328 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.672 0.328 0.000
N84.9 Polyp of female genital tract, unspecified
0.671 0.329 0.000
N84.8 Polyp of other parts of female genital tract
0.671 0.329 0.000
N84.3 Polyp of vulva
0.671 0.329 0.000
N84.2 Polyp of vagina
0.671 0.329 0.000
Z90.5 Acquired absence of kidney
0.670 0.330 0.000
D36.9 Benign neoplasm of unspecified site
0.669 0.331 0.000
D36.7 Other specified sites
0.669 0.331 0.000
D36.0 Lymph nodes
0.669 0.331 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.669 0.331 0.000
G41 Status epilepticus
0.669 0.331 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.669 0.331 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.669 0.331 0.000
K46 Unspecified abdominal hernia
0.668 0.332 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.667 0.333 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.667 0.333 0.000
C95 Leukaemia of unspecified cell type
0.667 0.333 0.000
C94 Other leukaemias of specified cell type
0.667 0.333 0.000
C93 Monocytic leukaemia
0.667 0.333 0.000
C88 Malignant immunoproliferative diseases
0.667 0.333 0.000
C86 Other specified types of T/NK-cell lymphoma
0.667 0.333 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.667 0.333 0.000
K77 Liver disorders in diseases classified elsewhere
0.667 0.333 0.000
K73 Chronic hepatitis, not elsewhere classified
0.667 0.333 0.000
K71 Toxic liver disease
0.667 0.333 0.000
L89.1 Stage II decubitus ulcer
0.666 0.334 0.000
G30-G32 Other degenerative diseases of the nervous system
0.666 0.334 0.000
K50-K52 Noninfective enteritis and colitis
0.665 0.334 0.000
S64 Injury of nerves at wrist and hand level
0.665 0.335 0.000
B25-B34 Other viral diseases
0.665 0.335 0.000
L90.0 Lichen sclerosus et atrophicus
0.664 0.335 0.000
S50-S59 Injuries to the elbow and forearm
0.663 0.337 0.000
C67 Malignant neoplasm of bladder
0.663 0.337 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.663 0.337 0.000
N80.6 Endometriosis in cutaneous scar
0.662 0.338 0.000
N80.5 Endometriosis of intestine
0.662 0.338 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.662 0.338 0.000
L04 Acute lymphadenitis
0.662 0.338 0.000
L01 Impetigo
0.662 0.338 0.000
L00 Staphylococcal scalded skin syndrome
0.662 0.338 0.000
K35-K38 Diseases of appendix
0.662 0.338 0.000
G91.9 Hydrocephalus, unspecified
0.661 0.339 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.658 0.342 0.000
N94.6 Dysmenorrhoea, unspecified
0.658 0.342 0.000
K72 Hepatic failure, not elsewhere classified
0.658 0.342 0.000
N41 Inflammatory diseases of prostate
0.657 0.343 0.000
G44 Other headache syndromes
0.657 0.343 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.657 0.343 0.000
K66.0 Peritoneal adhesions
0.657 0.343 0.000
G93.7 Reye's syndrome
0.656 0.344 0.000
G93.5 Compression of brain
0.656 0.344 0.000
G93.4 Encephalopathy, unspecified
0.656 0.344 0.000
G93.2 Benign intracranial hypertension
0.656 0.344 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.656 0.344 0.000
G93.0 Cerebral cysts
0.656 0.344 0.000
M86-M90 Other osteopathies
0.654 0.346 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.653 0.347 0.000
T90 Sequelae of injuries of head
0.652 0.348 0.000
N89 Other noninflammatory disorders of vagina
0.651 0.349 0.000
L30 Other dermatitis
0.650 0.350 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.650 0.350 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.650 0.350 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.650 0.350 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.648 0.352 0.000
N80.3 Endometriosis of pelvic peritoneum
0.647 0.353 0.000
D32.0 Cerebral meninges
0.647 0.353 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.647 0.353 0.000
H53.8 Other visual disturbances
0.646 0.354 0.000
M65-M68 Disorders of synovium and tendon
0.646 0.354 0.000
G81.9 Hemiplegia, unspecified
0.645 0.355 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.645 0.355 0.000
M22 Disorders of patella
0.645 0.355 0.000
D80-D89 Certain disorders involving the immune mechanism
0.643 0.357 0.000
Z85.6 Personal history of leukaemia
0.643 0.357 0.000
S69 Other and unspecified injuries of wrist and hand
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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