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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78446584
log Bayes Factor = 7.86467
Chromosome 2   position 130,663,894  (GRCh37) Explore rs78446584 on Ensembl!
Variant rs78446584 is part of Cluster X0084

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M75 Shoulder lesions
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M75.4 Impingement syndrome of shoulder
0.998 0.002 0.000
M50-M54 Other dorsopathies
0.997 0.003 0.000
M75.1 Rotator cuff syndrome
0.995 0.005 0.000
Chapter V Mental and behavioural disorders
0.993 0.007 0.000
M54 Dorsalgia
0.993 0.007 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.988 0.012 0.000
M54.2 Cervicalgia
0.988 0.012 0.000
M54.22 Cervicalgia (Cervical region)
0.982 0.018 0.000
Chapter VII Diseases of the eye and adnexa
0.972 0.028 0.000
M75.3 Calcific tendinitis of shoulder
0.963 0.037 0.000
Chapter X Diseases of the respiratory system
0.962 0.038 0.000
H40-H42 Glaucoma
0.956 0.044 0.000
J09-J18 Influenza and pneumonia
0.949 0.051 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.947 0.053 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.947 0.053 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.945 0.055 0.000
H40 Glaucoma
0.945 0.055 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.934 0.066 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.928 0.072 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.924 0.076 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.916 0.084 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.910 0.090 0.000
J18 Pneumonia, organism unspecified
0.908 0.092 0.000
Chapter XIV Diseases of the genitourinary system
0.907 0.093 0.000
F10.0 Acute intoxication
0.905 0.095 0.000
N20-N23 Urolithiasis
0.904 0.096 0.000
N20 Calculus of kidney and ureter
0.902 0.098 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.900 0.100 0.000
S90-S99 Injuries to the ankle and foot
0.893 0.107 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.891 0.109 0.000
M70.4 Prepatellar bursitis
0.890 0.110 0.000
W00-W19 Falls
0.890 0.110 0.000
S80-S89 Injuries to the knee and lower leg
0.883 0.117 0.000
N20.1 Calculus of ureter
0.882 0.118 0.000
Y86 Sequelae of other accidents
0.880 0.120 0.000
Chapter I Certain infectious and parasitic diseases
0.876 0.124 0.000
M86-M90 Other osteopathies
0.876 0.124 0.000
M65-M68 Disorders of synovium and tendon
0.874 0.126 0.000
H40.1 Primary open-angle glaucoma
0.869 0.131 0.000
H40.0 Glaucoma suspect
0.864 0.136 0.000
M05-M14 Inflammatory polyarthropathies
0.863 0.137 0.000
M50 Cervical disk disorders
0.853 0.147 0.000
F99-F99 Unspecified mental disorder
0.853 0.147 0.000
M70.46 Prepatellar bursitis-Lower Leg
0.849 0.151 0.000
T90 Sequelae of injuries of head
0.847 0.153 0.000
S80 Superficial injury of lower leg
0.845 0.155 0.000
T79-T79 Certain early complications of trauma
0.843 0.157 0.000
M54.9 Dorsalgia, unspecified
0.842 0.158 0.000
J95-J99 Other diseases of the respiratory system
0.841 0.159 0.000
Y52 Agents primarily affecting the cardiovascular system
0.840 0.160 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.839 0.161 0.000
N25-N29 Other disorders of kidney and ureter
0.838 0.162 0.000
S70-S79 Injuries to the hip and thigh
0.835 0.165 0.000
H55-H59 Other disorders of eye and adnexa
0.834 0.166 0.000
J17 Pneumonia in diseases classified elsewhere
0.832 0.168 0.000
M20-M25 Other joint disorders
0.829 0.171 0.000
F30-F39 Mood [affective] disorders
0.828 0.172 0.000
M54.3 Sciatica
0.827 0.173 0.000
J40-J47 Chronic lower respiratory diseases
0.824 0.176 0.000
M54.29 Cervicalgia-Site unspe
0.821 0.179 0.000
N20.0 Calculus of kidney
0.821 0.179 0.000
B35-B49 Mycoses
0.821 0.179 0.000
J18.9 Pneumonia, unspecified
0.820 0.180 0.000
F41 Other anxiety disorders
0.818 0.182 0.000
N30-N39 Other diseases of urinary system
0.807 0.193 0.000
M80-M85 Disorders of bone density and structure
0.806 0.194 0.000
S32 Fracture of lumbar spine and pelvis
0.806 0.194 0.000
H53-H54 Visual disturbances and blindness
0.804 0.196 0.000
M65 Synovitis and tenosynovitis
0.803 0.197 0.000
M35 Other systemic involvement of connective tissue
0.801 0.199 0.000
F10.1 Harmful use
0.798 0.202 0.000
X20-X29 Contact with venomous animals and plants
0.794 0.206 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.793 0.207 0.000
Chapter XXII Codes for special purposes
0.793 0.207 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.790 0.210 0.000
Y88 Sequelae of surgical and medical care as external cause
0.785 0.215 0.000
M70.7 Other bursitis of hip
0.784 0.216 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.783 0.217 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.783 0.217 0.000
Y48 Anaesthetics and therapeutic gases
0.781 0.219 0.000
T93 Sequelae of injuries of lower limb
0.779 0.221 0.000
S00-S09 Injuries to the head
0.779 0.221 0.000
J98 Other respiratory disorders
0.778 0.222 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.777 0.222 0.000
S91 Open wound of ankle and foot
0.776 0.224 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.776 0.224 0.000
H40.2 Primary angle-closure glaucoma
0.774 0.226 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.772 0.228 0.000
M35.3 Polymyalgia rheumatica
0.772 0.228 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.770 0.230 0.000
X60-X84 Intentional self-harm
0.769 0.231 0.000
J18.1 Lobar pneumonia, unspecified
0.769 0.231 0.000
M65.3 Trigger finger
0.768 0.232 0.000
N23 Unspecified renal colic
0.767 0.233 0.000
N30 Cystitis
0.766 0.234 0.000
H40.5 Glaucoma secondary to other eye disorders
0.764 0.236 0.000
M89 Other disorders of bone
0.764 0.236 0.000
M00-M03 Infectious arthropathies
0.764 0.236 0.000
J44 Other chronic obstructive pulmonary disease
0.763 0.237 0.000
M53 Other dorsopathies, not elsewhere classified
0.763 0.237 0.000
B37 Candidiasis
0.761 0.239 0.000
T21 Burn and corrosion of trunk
0.761 0.239 0.000
W10 Fall on and from stairs and steps
0.760 0.240 0.000
M71 Other bursopathies
0.758 0.242 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.757 0.243 0.000
M50.1 Cervical disk disorder with radiculopathy
0.755 0.245 0.000
H40.8 Other glaucoma
0.755 0.245 0.000
F99 Mental disorder, not otherwise specified
0.752 0.248 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.751 0.249 0.000
H57 Other disorders of eye and adnexa
0.751 0.249 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.751 0.249 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.749 0.250 0.000
J18.0 Bronchopneumonia, unspecified
0.749 0.251 0.000
M91-M94 Chondropathies
0.747 0.253 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.747 0.253 0.000
S40-S49 Injuries to the shoulder and upper arm
0.746 0.254 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.746 0.254 0.000
T90.9 Sequelae of unspecified injury of head
0.743 0.257 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.743 0.257 0.000
M54.1 Radiculopathy
0.743 0.257 0.000
M65.34 Trigger finger-Hand
0.743 0.257 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.741 0.259 0.000
M75.2 Bicipital tendinitis
0.740 0.260 0.000
T66-T78 Other and unspecified effects of external causes
0.740 0.260 0.000
M22 Disorders of patella
0.739 0.261 0.000
M90 Osteopathies in diseases classified elsewhere
0.739 0.261 0.000
Q80-Q89 Other congenital malformations
0.738 0.262 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.738 0.262 0.000
M60-M63 Disorders of muscles
0.738 0.262 0.000
M50.3 Other cervical disk degeneration
0.738 0.262 0.000
T98 Sequelae of other and unspecified effects of external causes
0.737 0.263 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.736 0.264 0.000
N20.9 Urinary calculus, unspecified
0.736 0.264 0.000
N20.2 Calculus of kidney with calculus of ureter
0.736 0.264 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.735 0.265 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.734 0.266 0.000
A00-A09 Intestinal infectious diseases
0.732 0.268 0.000
S10-S19 Injuries to the neck
0.731 0.269 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.730 0.270 0.000
H50 Other strabismus
0.729 0.271 0.000
F60-F69 Disorders of adult personality and behaviour
0.729 0.271 0.000
Y40 Systemic antibiotics
0.729 0.271 0.000
S80.9 Superficial injury of lower leg, unspecified
0.727 0.273 0.000
F33 Recurrent depressive disorder
0.727 0.273 0.000
S70 Superficial injury of hip and thigh
0.725 0.275 0.000
S80.0 Contusion of knee
0.725 0.275 0.000
X50-X57 Overexertion, travel and privation
0.724 0.276 0.000
J98.1 Pulmonary collapse
0.724 0.276 0.000
J17.1 Pneumonia in viral diseases classified elsewhere
0.724 0.276 0.000
V20-V29 Motorcycle rider injured in transport accident
0.723 0.277 0.000
N35 Urethral stricture
0.722 0.278 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.721 0.279 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.720 0.280 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.718 0.282 0.000
M75.8 Other shoulder lesions
0.717 0.283 0.000
M75.9 Shoulder lesion, unspecified
0.717 0.283 0.000
M76 Enthesopathies of lower limb, excluding foot
0.717 0.283 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
Y00-Y09 Assault
0.715 0.284 0.000
B37.0 Candidal stomatitis
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.288 0.000
F70-F79 Mental retardation
0.712 0.288 0.000
M54.8 Other dorsalgia
0.712 0.288 0.000
M54.0 Panniculitis affecting regions of neck and back
0.712 0.288 0.000
T33-T35 Frostbite
0.712 0.288 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.712 0.288 0.000
T00-T07 Injuries involving multiple body regions
0.712 0.288 0.000
S92 Fracture of foot, except ankle
0.710 0.290 0.000
J14 Pneumonia due to Haemophilus influenzae
0.709 0.291 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.709 0.291 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.709 0.291 0.000
M54.37 Sciatica (Lumbosacral region)
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.291 0.000
Y10-Y34 Event of undetermined intent
0.708 0.291 0.000
X85-X99 Assault
0.708 0.291 0.000
X30-X39 Exposure to forces of nature
0.708 0.291 0.000
X10-X19 Contact with heat and hot substances
0.708 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.708 0.291 0.000
W75-W84 Other accidental threats to breathing
0.708 0.291 0.000
W65-W74 Accidental drowning and submersion
0.708 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.708 0.291 0.000
V95-V97 Air and space transport accidents
0.708 0.291 0.000
V90-V94 Water transport accidents
0.708 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.708 0.291 0.000
W50-W64 Exposure to animate mechanical forces
0.708 0.291 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.708 0.292 0.000
M54.27 Cervicalgia-Lumbosacral
0.708 0.292 0.000
M54.26 Cervicalgia-Lumbar
0.708 0.292 0.000
M54.25 Cervicalgia-Thoracolumbar
0.708 0.292 0.000
M54.24 Cervicalgia-Thoracic
0.708 0.292 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.708 0.292 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.708 0.292 0.000
M54.20 Cervicalgia-Mult site
0.708 0.292 0.000
Y85 Sequelae of transport accidents
0.708 0.292 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.707 0.293 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.706 0.294 0.000
M54.6 Pain in thoracic spine
0.703 0.297 0.000
M80 Osteoporosis with pathological fracture
0.701 0.299 0.000
M13 Other arthritis
0.701 0.299 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.700 0.299 0.000
F43 Reaction to severe stress, and adjustment disorders
0.700 0.300 0.000
S32.0 Fracture of lumbar vertebra
0.700 0.300 0.000
F10.4 Withdrawal state with delirium
0.697 0.303 0.000
F41.1 Generalised anxiety disorder
0.697 0.303 0.000
N30.8 Other cystitis
0.695 0.305 0.000
F10.3 Withdrawal state
0.695 0.305 0.000
S91.3 Open wound of other parts of foot
0.692 0.308 0.000
T20 Burn and corrosion of head and neck
0.692 0.308 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.692 0.308 0.000
Y42.7 Androgens and anabolic congeners
0.692 0.308 0.000
Y57 Other and unspecified drugs and medicaments
0.691 0.309 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.690 0.310 0.000
V80-V89 Other land transport accidents
0.688 0.312 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.687 0.313 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.687 0.313 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.687 0.313 0.000
F10.9 Unspecified mental and behavioural disorder
0.686 0.314 0.000
H42 Glaucoma in diseases classified elsewhere
0.685 0.314 0.000
S36 Injury of intra-abdominal organs
0.684 0.316 0.000
T23 Burn and corrosion of wrist and hand
0.684 0.316 0.000
J10 Influenza due to identified influenza virus
0.683 0.316 0.000
J15.1 Pneumonia due to Pseudomonas
0.682 0.318 0.000
M54.4 Lumbago with sciatica
0.681 0.319 0.000
W06 Fall involving bed
0.681 0.319 0.000
N27 Small kidney of unknown cause
0.681 0.319 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.680 0.320 0.000
J12 Viral pneumonia, not elsewhere classified
0.680 0.320 0.000
J09 Influenza due to certain identified influenza virus
0.680 0.320 0.000
J46 Status asthmaticus
0.680 0.320 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.679 0.321 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.679 0.321 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.679 0.321 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.679 0.321 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.679 0.321 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.679 0.321 0.000
F11 Mental and behavioural disorders due to use of opioids
0.679 0.321 0.000
S90 Superficial injury of ankle and foot
0.679 0.321 0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.679 0.321 0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.679 0.321 0.000
M70.5 Other bursitis of knee
0.679 0.321 0.000
M70.3 Other bursitis of elbow
0.679 0.321 0.000
M70.1 Bursitis of hand
0.679 0.321 0.000
M70.0 Chronic crepitant synovitis of hand and wrist
0.679 0.321 0.000
V40-V49 Car occupant injured in transport accident
0.679 0.321 0.000
M11 Other crystal arthropathies
0.679 0.321 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.678 0.322 0.000
Y89 Sequelae of other external causes
0.678 0.322 0.000
H40.6 Glaucoma secondary to drugs
0.678 0.322 0.000
H40.4 Glaucoma secondary to eye inflammation
0.678 0.322 0.000
H40.3 Glaucoma secondary to eye trauma
0.678 0.322 0.000
M70.2 Olecranon bursitis
0.677 0.323 0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances
0.676 0.324 0.000
W08 Fall involving other furniture
0.676 0.324 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.676 0.324 0.000
W17 Other fall from one level to another
0.675 0.325 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.674 0.326 0.000
A04 Other bacterial intestinal infections
0.674 0.326 0.000
Q00-Q07 Congenital malformations of the nervous system
0.674 0.326 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.673 0.327 0.000
H50.9 Strabismus, unspecified
0.673 0.327 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.673 0.327 0.000
J11 Influenza, virus not identified
0.672 0.327 0.000
V10-V19 Pedal cyclist injured in transport accident
0.672 0.328 0.000
Q50-Q56 Congenital malformations of genital organs
0.671 0.329 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.671 0.329 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.671 0.329 0.000
W07 Fall involving chair
0.671 0.329 0.000
T95 Sequelae of burns, corrosions and frostbite
0.670 0.330 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.670 0.330 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.670 0.330 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.670 0.330 0.000
T91 Sequelae of injuries of neck and trunk
0.668 0.332 0.000
F42 Obsessive-compulsive disorder
0.668 0.332 0.000
F33.1 Recurrent depressive disorder, current episode moderate
0.668 0.332 0.000
M77 Other enthesopathies
0.667 0.333 0.000
M70.75 Other bursitis of hip-Pelvic/Thigh
0.667 0.333 0.000
F10.8 Other mental and behavioural disorders
0.666 0.334 0.000
F10.7 Residual and late-onset psychotic disorder
0.666 0.334 0.000
F10.6 Amnesic syndrome
0.666 0.334 0.000
F10.5 Psychotic disorder
0.666 0.334 0.000
S89 Other and unspecified injuries of lower leg
0.666 0.334 0.000
M07 Psoriatic and enteropathic arthropathies
0.664 0.336 0.000
T25 Burn and corrosion of ankle and foot
0.663 0.337 0.000
B49 Unspecified mycosis
0.660 0.340 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.659 0.340 0.000
N30.1 Interstitial cystitis (chronic)
0.659 0.341 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.659 0.341 0.000
H54 Blindness and low vision
0.659 0.341 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.658 0.342 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.657 0.343 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.656 0.343 0.000
S37 Injury of urinary and pelvic organs
0.656 0.343 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.656 0.343 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.656 0.343 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.656 0.343 0.000
S31 Open wound of abdomen, lower back and pelvis
0.656 0.343 0.000
M70.6 Trochanteric bursitis
0.656 0.344 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.656 0.344 0.000
W19 Unspecified fall
0.656 0.344 0.000
N36 Other disorders of urethra
0.656 0.344 0.000
F30 Manic episode
0.656 0.344 0.000
X23 Contact with hornets, wasps and bees
0.655 0.345 0.000
T90.8 Sequelae of other specified injuries of head
0.654 0.345 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.653 0.347 0.000
Y59 Other and unspecified vaccines and biological substances
0.652 0.347 0.000
Y58 Bacterial vaccines
0.652 0.347 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.652 0.347 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.652 0.347 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.652 0.347 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.652 0.347 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.652 0.347 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.652 0.347 0.000
J18.8 Other pneumonia, organism unspecified
0.651 0.349 0.000
J18.2 Hypostatic pneumonia, unspecified
0.651 0.349 0.000
J17.2 Pneumonia in mycoses
0.651 0.349 0.000
T90.5 Sequelae of intracranial injury
0.650 0.350 0.000
N75 Diseases of Bartholin's gland
0.650 0.350 0.000
Y48.3 Local anaesthetics
0.650 0.350 0.000
H10-H13 Disorders of conjunctiva
0.650 0.350 0.000
M22.2 Patellofemoral disorders
0.650 0.350 0.000
N30.3 Trigonitis
0.649 0.351 0.000
N28.8 Other specified disorders of kidney and ureter
0.649 0.351 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.648 0.352 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.647 0.353 0.000
W18 Other fall on same level
0.647 0.353 0.000
B44 Aspergillosis
0.647 0.353 0.000
M06 Other rheumatoid arthritis
0.647 0.353 0.000
H40.9 Glaucoma, unspecified
0.647 0.353 0.000
M35.0 Sicca syndrome [Sjogren]
0.646 0.354 0.000
F48 Other neurotic disorders
0.646 0.354 0.000
F44 Dissociative [conversion] disorders
0.646 0.354 0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand
0.645 0.355 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.645 0.355 0.000
M66 Spontaneous rupture of synovium and tendon
0.644 0.355 0.000
J00-J06 Acute upper respiratory infections
0.644 0.356 0.000
T92 Sequelae of injuries of upper limb
0.644 0.356 0.000
M14 Arthropathies in other diseases classified elsewhere
0.644 0.356 0.000
T21.3 Burn of third degree of trunk
0.644 0.356 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.644 0.356 0.000
N99-N99 Other disorders of the genitourinary system
0.643 0.357 0.000
N35.9 Urethral stricture, unspecified
0.643 0.357 0.000
J47 Bronchiectasis
0.643 0.357 0.000
M85 Other disorders of bone density and structure
0.643 0.357 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.642 0.358 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.641 0.358 0.000
F80-F89 Disorders of psychological development
0.641 0.359 0.000
M90.7 Fracture of bone in neoplastic disease
0.641 0.359 0.000
S99 Other and unspecified injuries of ankle and foot
0.640 0.359 0.000
S98 Traumatic amputation of ankle and foot
0.640 0.359 0.000
S97 Crushing injury of ankle and foot
0.640 0.359 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.640 0.359 0.000
S95 Injury of blood vessels at ankle and foot level
0.640 0.359 0.000
S94 Injury of nerves at ankle and foot level
0.640 0.359 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.640 0.359 0.000
M24 Other specific joint derangements
0.640 0.360 0.000
N30.9 Cystitis, unspecified
0.640 0.360 0.000
M89.8 Other specified disorders of bone
0.640 0.360 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.639 0.361 0.000
Q35-Q37 Cleft lip and cleft palate
0.639 0.361 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.639 0.361 0.000
S32.4 Fracture of acetabulum
0.639 0.361 0.000
M70.49 Prepatellar bursitis-Site unspec
0.638 0.362 0.000
M70.48 Prepatellar bursitis-Other
0.638 0.362 0.000
M70.47 Prepatellar bursitis-Ankle/Foot
0.638 0.362 0.000
M70.45 Prepatellar bursitis-Pelvic/Thigh
0.638 0.362 0.000
M70.44 Prepatellar bursitis-Hand
0.638 0.362 0.000
M70.43 Prepatellar bursitis-Forearm
0.638 0.362 0.000
M70.42 Prepatellar bursitis-Upper arm
0.638 0.362 0.000
M70.41 Prepatellar bursitis-Shldr region
0.638 0.362 0.000
M70.40 Prepatellar bursitis-Mult sites
0.638 0.362 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.638 0.362 0.000
W15 Fall from cliff
0.638 0.362 0.000
W14 Fall from tree
0.638 0.362 0.000
W12 Fall on and from scaffolding
0.638 0.362 0.000
W11 Fall on and from ladder
0.638 0.362 0.000
W09 Fall involving playground equipment
0.638 0.362 0.000
W05 Fall involving wheelchair
0.638 0.362 0.000
W04 Fall while being carried or supported by other persons
0.638 0.362 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.638 0.362 0.000
W00 Fall on same level involving ice and snow
0.638 0.362 0.000
W10.8 Other specified place
0.637 0.362 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.637 0.363 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.636 0.363 0.000
M87 Osteonecrosis
0.636 0.363 0.000
F45 Somatoform disorders
0.636 0.363 0.000
X59 Exposure to unspecified factor
0.636 0.364 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.635 0.365 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.634 0.366 0.000
M54.36 Sciatica (Lumbar region)
0.634 0.366 0.000
S88 Traumatic amputation of lower leg
0.633 0.367 0.000
S87 Crushing injury of lower leg
0.633 0.367 0.000
S85 Injury of blood vessels at lower leg level
0.633 0.367 0.000
S84 Injury of nerves at lower leg level
0.633 0.367 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.631 0.369 0.000
N28.1 Cyst of kidney, acquired
0.631 0.369 0.000
N71 Inflammatory disease of uterus, except cervix
0.630 0.370 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.630 0.370 0.000
S30.2 Contusion of external genital organs
0.630 0.370 0.000
F39 Unspecified mood [affective] disorder
0.629 0.371 0.000
H43-H45 Disorders of vitreous body and globe
0.629 0.371 0.000
S79 Other and unspecified injuries of hip and thigh
0.629 0.371 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.628 0.372 0.000
B50-B64 Protozoal diseases
0.628 0.372 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.628 0.372 0.000
A75-A79 Rickettsioses
0.628 0.372 0.000
A70-A74 Other diseases caused by chlamydiae
0.628 0.372 0.000
A65-A69 Other spirochaetal diseases
0.628 0.372 0.000
A20-A28 Certain zoonotic bacterial diseases
0.628 0.372 0.000
A15-A19 Tuberculosis
0.628 0.372 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.628 0.372 0.000
B02 Zoster [herpes zoster]
0.627 0.373 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.627 0.373 0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot
0.627 0.373 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.627 0.373 0.000
B65-B83 Helminthiases
0.625 0.375 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.624 0.376 0.000
F40 Phobic anxiety disorders
0.623 0.376 0.000
Y48.4 Anaesthetic, unspecified
0.623 0.377 0.000
S02 Fracture of skull and facial bones
0.623 0.377 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.622 0.378 0.000
M72 Fibroblastic disorders
0.622 0.378 0.000
Q60-Q64 Congenital malformations of the urinary system
0.621 0.379 0.000
B37.9 Candidiasis, unspecified
0.620 0.380 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.619 0.381 0.000
M12 Other specific arthropathies
0.619 0.381 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.619 0.381 0.000
M08 Juvenile arthritis
0.619 0.381 0.000
H55 Nystagmus and other irregular eye movements
0.617 0.382 0.000
A04.8 Other specified bacterial intestinal infections
0.617 0.383 0.000
R79 Other abnormal findings of blood chemistry
0.616 0.384 0.000
H53 Visual disturbances
0.616 0.384 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.616 0.384 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.616 0.384 0.000
M31 Other necrotising vasculopathies
0.615 0.385 0.000
S20-S29 Injuries to the thorax
0.613 0.387 0.000
M50.9 Cervical disk disorder, unspecified
0.612 0.388 0.000
M50.8 Other cervical disk disorders
0.612 0.388 0.000
M05 Seropositive rheumatoid arthritis
0.611 0.389 0.000
M30 Polyarteritis nodosa and related conditions
0.611 0.389 0.000
S86 Injury of muscle and tendon at lower leg level
0.609 0.391 0.000
M54.5 Low back pain
0.607 0.393 0.000
T90.3 Sequelae of injury of cranial nerves
0.607 0.393 0.000
T90.1 Sequelae of open wound of head
0.607 0.393 0.000
T90.0 Sequelae of superficial injury of head
0.607 0.393 0.000
R50-R69 General symptoms and signs
0.607 0.393 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.606 0.394 0.000
S80.7 Multiple superficial injuries of lower leg
0.606 0.394 0.000
R04 Haemorrhage from respiratory passages
0.605 0.395 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.605 0.395 0.000
M89.0 Algoneurodystrophy
0.604 0.396 0.000
M54.12 Radiculopathy (Cervical region)
0.604 0.396 0.000
J98.6 Disorders of diaphragm
0.603 0.396 0.000
M82 Osteoporosis in diseases classified elsewhere
0.603 0.397 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.603 0.397 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.603 0.397 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.603 0.397 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.603 0.397 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.603 0.397 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.603 0.397 0.000
T93.0 Sequelae of open wound of lower limb
0.603 0.397 0.000
B99 Other and unspecified infectious diseases
0.603 0.397 0.000
J96 Respiratory failure, not elsewhere classified
0.603 0.397 0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand
0.603 0.397 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.602 0.398 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.602 0.398 0.000
Y52.7 Peripheral vasodilators
0.602 0.398 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.602 0.398 0.000
Y52.1 Calcium-channel blockers
0.602 0.398 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.602 0.398 0.000
X48 Accidental poisoning by and exposure to pesticides
0.601 0.398 0.000
X46 Accidental poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.601 0.398 0.000
X45 Accidental poisoning by and exposure to alcohol
0.601 0.398 0.000
X44 Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.601 0.398 0.000
X43 Accidental poisoning by and exposure to other drugs acting on the autonomic nervous system
0.601 0.398 0.000
X42 Accidental poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.601 0.398 0.000
X40 Accidental poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.601 0.398 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.601 0.399 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.601 0.399 0.000
N25 Disorders resulting from impaired renal tubular function
0.601 0.399 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.600 0.400 0.000
A80-A89 Viral infections of the central nervous system
0.599 0.401 0.000
R51 Headache
0.599 0.401 0.000
S78 Traumatic amputation of hip and thigh
0.598 0.401 0.000
S77 Crushing injury of hip and thigh
0.598 0.401 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.598 0.401 0.000
S75 Injury of blood vessels at hip and thigh level
0.598 0.401 0.000
S74 Injury of nerves at hip and thigh level
0.598 0.401 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.598 0.401 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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