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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78530398
log Bayes Factor = 15.7707
Chromosome 13   position 32,365,235  (GRCh37) Explore rs78530398 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
Chapter VIII Diseases of the ear and mastoid process
0.997 0.003 0.000
K70-K77 Diseases of liver
0.997 0.003 0.000
Chapter XI Diseases of the digestive system
0.995 0.005 0.000
I10-I15 Hypertensive diseases
0.995 0.005 0.000
Chapter VII Diseases of the eye and adnexa
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.994 0.006 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.993 0.007 0.000
K76 Other diseases of liver
0.991 0.009 0.000
I10 Essential (primary) hypertension
0.991 0.009 0.000
Chapter XIV Diseases of the genitourinary system
0.990 0.010 0.000
N17-N19 Renal failure
0.989 0.011 0.000
M05-M14 Inflammatory polyarthropathies
0.981 0.019 0.000
M06 Other rheumatoid arthritis
0.979 0.021 0.000
E70-E90 Metabolic disorders
0.978 0.022 0.000
M06.9 Rheumatoid arthritis, unspecified
0.976 0.024 0.000
Chapter VI Diseases of the nervous system
0.972 0.028 0.000
M50-M54 Other dorsopathies
0.969 0.031 0.000
I21 Acute myocardial infarction
0.968 0.032 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.968 0.032 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.967 0.033 0.000
K50-K52 Noninfective enteritis and colitis
0.967 0.033 0.000
K51 Ulcerative colitis
0.962 0.038 0.000
K74 Fibrosis and cirrhosis of liver
0.960 0.040 0.000
N19 Unspecified renal failure
0.959 0.041 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.956 0.044 0.000
H90-H95 Other disorders of ear
0.953 0.047 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.952 0.048 0.000
N17 Acute renal failure
0.952 0.048 0.000
S20-S29 Injuries to the thorax
0.946 0.054 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.946 0.054 0.000
G90-G99 Other disorders of the nervous system
0.942 0.058 0.000
I25 Chronic ischaemic heart disease
0.942 0.058 0.000
M51 Other intervertebral disk disorders
0.940 0.060 0.000
H60-H62 Diseases of external ear
0.940 0.060 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.937 0.063 0.000
T66-T78 Other and unspecified effects of external causes
0.936 0.064 0.000
I21.9 Acute myocardial infarction, unspecified
0.935 0.065 0.000
K75 Other inflammatory liver diseases
0.929 0.071 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.928 0.072 0.000
N17.9 Acute renal failure, unspecified
0.925 0.075 0.000
M45-M49 Spondylopathies
0.924 0.076 0.000
I20 Angina pectoris
0.924 0.076 0.000
S00-S09 Injuries to the head
0.922 0.078 0.000
M51.2 Other specified intervertebral disk displacement
0.922 0.078 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.921 0.079 0.000
N10-N16 Renal tubulo-interstitial diseases
0.919 0.081 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.917 0.083 0.000
N18 Chronic renal failure
0.914 0.086 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.909 0.091 0.000
Chapter I Certain infectious and parasitic diseases
0.909 0.091 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.906 0.094 0.000
K51.2 Ulcerative (chronic) proctitis
0.906 0.094 0.000
I25.2 Old myocardial infarction
0.906 0.094 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.906 0.094 0.000
Chapter XXI Factors influencing health status and contact with health services
0.905 0.095 0.000
H65-H75 Diseases of middle ear and mastoid
0.905 0.095 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.905 0.095 0.000
G62 Other polyneuropathies
0.902 0.098 0.000
M46 Other inflammatory spondylopathies
0.902 0.098 0.000
N13 Obstructive and reflux uropathy
0.900 0.100 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.900 0.100 0.000
D60-D64 Aplastic and other anaemias
0.899 0.101 0.000
Z72 Problems related to lifestyle
0.896 0.104 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.895 0.105 0.000
H43-H45 Disorders of vitreous body and globe
0.895 0.105 0.000
S90-S99 Injuries to the ankle and foot
0.895 0.105 0.000
E83 Disorders of mineral metabolism
0.893 0.107 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.893 0.107 0.000
H92 Otalgia and effusion of ear
0.892 0.108 0.000
N30-N39 Other diseases of urinary system
0.892 0.108 0.000
K76.9 Liver disease, unspecified
0.891 0.109 0.000
E86 Volume depletion
0.887 0.113 0.000
N13.3 Other and unspecified hydronephrosis
0.882 0.118 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.882 0.118 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.881 0.119 0.000
K51.8 Other ulcerative colitis
0.881 0.119 0.000
K74.3 Primary biliary cirrhosis
0.881 0.119 0.000
Y43 Primarily systemic agents
0.880 0.120 0.000
N32 Other disorders of bladder
0.878 0.122 0.000
H60 Otitis externa
0.876 0.124 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.875 0.125 0.000
I05-I09 Chronic rheumatic heart diseases
0.875 0.125 0.000
K90-K93 Other diseases of the digestive system
0.874 0.125 0.000
E40-E46 Malnutrition
0.874 0.126 0.000
I11 Hypertensive heart disease
0.871 0.129 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.870 0.130 0.000
D64 Other anaemias
0.869 0.131 0.000
N18.9 Chronic renal failure, unspecified
0.868 0.132 0.000
E89.0 Postprocedural hypothyroidism
0.867 0.133 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.867 0.133 0.000
H71 Cholesteatoma of middle ear
0.866 0.134 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.864 0.136 0.000
K72 Hepatic failure, not elsewhere classified
0.863 0.137 0.000
I60-I69 Cerebrovascular diseases
0.862 0.138 0.000
E83.1 Disorders of iron metabolism
0.861 0.139 0.000
K75.9 Inflammatory liver disease, unspecified
0.861 0.139 0.000
M86-M90 Other osteopathies
0.861 0.139 0.000
M91-M94 Chondropathies
0.861 0.139 0.000
L60-L75 Disorders of skin appendages
0.859 0.141 0.000
K76.8 Other specified diseases of liver
0.859 0.141 0.000
G62.9 Polyneuropathy, unspecified
0.858 0.142 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.857 0.143 0.000
Z72.0 Tobacco use
0.857 0.143 0.000
H92.1 Otorrhoea
0.857 0.143 0.000
T90 Sequelae of injuries of head
0.856 0.144 0.000
Y86 Sequelae of other accidents
0.851 0.149 0.000
G95 Other diseases of spinal cord
0.850 0.150 0.000
H04 Disorders of lachrymal system
0.850 0.150 0.000
K74.0 Hepatic fibrosis
0.850 0.150 0.000
H30-H36 Disorders of choroid and retina
0.849 0.151 0.000
D64.9 Anaemia, unspecified
0.848 0.152 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.848 0.152 0.000
T78 Adverse effects, not elsewhere classified
0.848 0.152 0.000
K92 Other diseases of digestive system
0.847 0.153 0.000
H90 Conductive and sensorineural hearing loss
0.843 0.157 0.000
K73 Chronic hepatitis, not elsewhere classified
0.840 0.160 0.000
W20-W49 Exposure to inanimate mechanical forces
0.840 0.160 0.000
I20.9 Angina pectoris, unspecified
0.835 0.165 0.000
M60-M63 Disorders of muscles
0.835 0.165 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.833 0.167 0.000
D68 Other coagulation defects
0.832 0.167 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.830 0.170 0.000
T51 Toxic effect of alcohol
0.829 0.171 0.000
H18 Other disorders of cornea
0.829 0.171 0.000
Z72.1 Alcohol use
0.826 0.174 0.000
Z75 Problems related to medical facilities and other health care
0.824 0.176 0.000
I25.3 Aneurysm of heart
0.824 0.176 0.000
Y43.3 Other antineoplastic drugs
0.823 0.177 0.000
N32.1 Vesicointestinal fistula
0.822 0.178 0.000
E10-E14 Diabetes mellitus
0.822 0.178 0.000
G95.9 Disease of spinal cord, unspecified
0.820 0.180 0.000
K51.9 Ulcerative colitis, unspecified
0.820 0.180 0.000
L72.0 Epidermal cyst
0.819 0.181 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.817 0.183 0.000
N18.3 Chronic kidney disease, stage 3
0.816 0.184 0.000
N32.8 Other specified disorders of bladder
0.815 0.185 0.000
N20-N23 Urolithiasis
0.815 0.185 0.000
T78.2 Anaphylactic shock, unspecified
0.814 0.186 0.000
E20-E35 Disorders of other endocrine glands
0.813 0.187 0.000
M06.4 Inflammatory polyarthropathy
0.812 0.188 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.811 0.189 0.000
T68 Hypothermia
0.805 0.195 0.000
S09 Other and unspecified injuries of head
0.805 0.195 0.000
Z74 Problems related to care-provider dependency
0.803 0.197 0.000
N13.8 Other obstructive and reflux uropathy
0.803 0.197 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.802 0.198 0.000
M80-M85 Disorders of bone density and structure
0.801 0.199 0.000
I22 Subsequent myocardial infarction
0.800 0.200 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.798 0.202 0.000
V20-V29 Motorcycle rider injured in transport accident
0.798 0.202 0.000
M40-M43 Deforming dorsopathies
0.797 0.203 0.000
H21 Other disorders of iris and ciliary body
0.797 0.203 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.796 0.204 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.795 0.205 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.792 0.208 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.791 0.209 0.000
Y88 Sequelae of surgical and medical care as external cause
0.790 0.210 0.000
E46 Unspecified protein-energy malnutrition
0.789 0.211 0.000
S27 Injury of other and unspecified intrathoracic organs
0.788 0.212 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.787 0.213 0.000
S22.0 Fracture of thoracic vertebra
0.787 0.213 0.000
D68.2 Hereditary deficiency of other clotting factors
0.787 0.213 0.000
H44 Disorders of globe
0.785 0.215 0.000
L71 Rosacea
0.785 0.215 0.000
B35-B49 Mycoses
0.784 0.216 0.000
T51.0 Ethanol
0.784 0.216 0.000
X60-X84 Intentional self-harm
0.783 0.217 0.000
N23 Unspecified renal colic
0.782 0.218 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.782 0.218 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.780 0.220 0.000
K92.0 Haematemesis
0.780 0.220 0.000
K72.9 Hepatic failure, unspecified
0.779 0.221 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.779 0.221 0.000
H60.9 Otitis externa, unspecified
0.779 0.221 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.778 0.222 0.000
Y57 Other and unspecified drugs and medicaments
0.776 0.224 0.000
A15-A19 Tuberculosis
0.775 0.225 0.000
S01 Open wound of head
0.775 0.225 0.000
I61 Intracerebral haemorrhage
0.773 0.227 0.000
H61 Other disorders of external ear
0.773 0.227 0.000
I20.1 Angina pectoris with documented spasm
0.773 0.227 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.773 0.227 0.000
I07 Rheumatic tricuspid valve diseases
0.773 0.227 0.000
I69 Sequelae of cerebrovascular disease
0.771 0.229 0.000
H40-H42 Glaucoma
0.770 0.230 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.768 0.232 0.000
G97.8 Other postprocedural disorders of nervous system
0.768 0.232 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.766 0.234 0.000
I23 Certain current complications following acute myocardial infarction
0.765 0.235 0.000
E11 Non-insulin-dependent diabetes mellitus
0.765 0.235 0.000
M51.8 Other specified intervertebral disk disorders
0.763 0.237 0.000
V01-V09 Pedestrian injured in transport accident
0.763 0.237 0.000
B99-B99 Other infectious diseases
0.762 0.238 0.000
G60 Hereditary and idiopathic neuropathy
0.762 0.238 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.759 0.240 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.758 0.242 0.000
H80-H83 Diseases of inner ear
0.758 0.242 0.000
H60.1 Cellulitis of external ear
0.757 0.243 0.000
N32.0 Bladder-neck obstruction
0.756 0.244 0.000
M86 Osteomyelitis
0.756 0.244 0.000
V80-V89 Other land transport accidents
0.754 0.246 0.000
K75.0 Abscess of liver
0.752 0.248 0.000
Z76 Persons encountering health services in other circumstances
0.751 0.249 0.000
Y52 Agents primarily affecting the cardiovascular system
0.750 0.250 0.000
M50 Cervical disk disorders
0.750 0.250 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.749 0.251 0.000
W21 Striking against or struck by sports equipment
0.749 0.251 0.000
I15 Secondary hypertension
0.748 0.251 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.749 0.251 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.747 0.253 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.747 0.253 0.000
H53-H54 Visual disturbances and blindness
0.746 0.254 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.746 0.254 0.000
E11.9 Without complications
0.745 0.255 0.000
Q80-Q89 Other congenital malformations
0.744 0.256 0.000
N13.4 Hydroureter
0.742 0.258 0.000
K75.8 Other specified inflammatory liver diseases
0.741 0.259 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.741 0.259 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.740 0.260 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.738 0.262 0.000
H50 Other strabismus
0.737 0.263 0.000
D61 Other aplastic anaemias
0.737 0.263 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.737 0.263 0.000
H33 Retinal detachments and breaks
0.736 0.264 0.000
K76.6 Portal hypertension
0.736 0.264 0.000
S02 Fracture of skull and facial bones
0.735 0.265 0.000
Z72.2 Drug use
0.734 0.266 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.732 0.268 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.731 0.269 0.000
D69 Purpura and other haemorrhagic conditions
0.731 0.269 0.000
X20-X29 Contact with venomous animals and plants
0.731 0.269 0.000
M06.3 Rheumatoid nodule
0.730 0.270 0.000
H43 Disorders of vitreous body
0.730 0.270 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.730 0.270 0.000
Q00-Q07 Congenital malformations of the nervous system
0.730 0.270 0.000
L72.1 Trichilemmal cyst
0.729 0.271 0.000
I08 Multiple valve diseases
0.729 0.271 0.000
B15-B19 Viral hepatitis
0.729 0.271 0.000
H05 Disorders of orbit
0.729 0.271 0.000
K73.9 Chronic hepatitis, unspecified
0.728 0.271 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.728 0.272 0.000
S29 Other and unspecified injuries of thorax
0.726 0.274 0.000
S01.8 Open wound of other parts of head
0.724 0.276 0.000
B65-B83 Helminthiases
0.723 0.277 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.722 0.277 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.722 0.278 0.000
E74 Other disorders of carbohydrate metabolism
0.722 0.278 0.000
T92 Sequelae of injuries of upper limb
0.722 0.278 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.721 0.279 0.000
M45 Ankylosing spondylitis
0.720 0.280 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.720 0.280 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.720 0.280 0.000
K74.5 Biliary cirrhosis, unspecified
0.719 0.281 0.000
S05 Injury of eye and orbit
0.718 0.281 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.718 0.282 0.000
M62 Other disorders of muscle
0.718 0.282 0.000
X50-X57 Overexertion, travel and privation
0.717 0.282 0.000
K74.6 Other and unspecified cirrhosis of liver
0.717 0.282 0.000
W22 Striking against or struck by other objects
0.717 0.283 0.000
G93 Other disorders of brain
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
L50-L54 Urticaria and erythema
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
K77 Liver disorders in diseases classified elsewhere
0.715 0.285 0.000
K71 Toxic liver disease
0.715 0.285 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.714 0.285 0.000
H90.3 Sensorineural hearing loss, bilateral
0.714 0.286 0.000
M05 Seropositive rheumatoid arthritis
0.714 0.286 0.000
I13 Hypertensive heart and renal disease
0.713 0.287 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.713 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.287 0.000
Y10-Y34 Event of undetermined intent
0.712 0.287 0.000
Y00-Y09 Assault
0.712 0.287 0.000
X85-X99 Assault
0.712 0.287 0.000
X30-X39 Exposure to forces of nature
0.712 0.287 0.000
X10-X19 Contact with heat and hot substances
0.712 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.287 0.000
W75-W84 Other accidental threats to breathing
0.712 0.287 0.000
W65-W74 Accidental drowning and submersion
0.712 0.287 0.000
W50-W64 Exposure to animate mechanical forces
0.712 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.287 0.000
V95-V97 Air and space transport accidents
0.712 0.287 0.000
V90-V94 Water transport accidents
0.712 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.287 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.712 0.288 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.712 0.288 0.000
K76.7 Hepatorenal syndrome
0.711 0.289 0.000
K76.5 Hepatic veno-occlusive disease
0.711 0.289 0.000
K76.4 Peliosis hepatis
0.711 0.289 0.000
K76.3 Infarction of liver
0.711 0.289 0.000
K76.2 Central haemorrhagic necrosis of liver
0.711 0.289 0.000
K76.1 Chronic passive congestion of liver
0.711 0.289 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.710 0.290 0.000
H16 Keratitis
0.710 0.290 0.000
S90 Superficial injury of ankle and foot
0.709 0.291 0.000
L71.9 Rosacea, unspecified
0.709 0.291 0.000
B50-B64 Protozoal diseases
0.709 0.291 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.709 0.291 0.000
H55-H59 Other disorders of eye and adnexa
0.709 0.291 0.000
M94 Other disorders of cartilage
0.708 0.292 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.708 0.292 0.000
W00-W19 Falls
0.708 0.292 0.000
E65-E68 Obesity and other hyperalimentation
0.707 0.293 0.000
M54 Dorsalgia
0.706 0.294 0.000
E85 Amyloidosis
0.705 0.295 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.704 0.296 0.000
S22.4 Multiple fractures of ribs
0.704 0.296 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.704 0.296 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.704 0.296 0.000
Z75.2 Other waiting period for investigation and treatment
0.704 0.296 0.000
T79-T79 Certain early complications of trauma
0.704 0.296 0.000
M14 Arthropathies in other diseases classified elsewhere
0.704 0.296 0.000
M12 Other specific arthropathies
0.704 0.296 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.704 0.296 0.000
M08 Juvenile arthritis
0.704 0.296 0.000
V10-V19 Pedal cyclist injured in transport accident
0.703 0.296 0.000
S99 Other and unspecified injuries of ankle and foot
0.703 0.297 0.000
S31 Open wound of abdomen, lower back and pelvis
0.702 0.297 0.000
M06.8 Other specified rheumatoid arthritis
0.702 0.298 0.000
M06.2 Rheumatoid bursitis
0.702 0.298 0.000
M06.1 Adult-onset Still's disease
0.702 0.298 0.000
H21.8 Other specified disorders of iris and ciliary body
0.702 0.298 0.000
T90.1 Sequelae of open wound of head
0.701 0.298 0.000
Q50-Q56 Congenital malformations of genital organs
0.701 0.299 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.701 0.299 0.000
E84 Cystic fibrosis
0.701 0.299 0.000
E79 Disorders of purine and pyrimidine metabolism
0.701 0.299 0.000
E77 Disorders of glycoprotein metabolism
0.701 0.299 0.000
E76 Disorders of glycosaminoglycan metabolism
0.701 0.299 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.701 0.299 0.000
E72 Other disorders of amino-acid metabolism
0.701 0.299 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.701 0.299 0.000
E70 Disorders of aromatic amino-acid metabolism
0.701 0.299 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.701 0.299 0.000
H18.9 Disorder of cornea, unspecified
0.701 0.299 0.000
G62.0 Drug-induced polyneuropathy
0.700 0.300 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.700 0.300 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.700 0.300 0.000
I07.1 Tricuspid insufficiency
0.699 0.301 0.000
A65-A69 Other spirochaetal diseases
0.699 0.301 0.000
H17 Corneal scars and opacities
0.698 0.302 0.000
E83.4 Disorders of magnesium metabolism
0.697 0.303 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.697 0.303 0.000
Z74.0 Reduced mobility
0.697 0.303 0.000
H69 Other disorders of Eustachian tube
0.696 0.304 0.000
M53 Other dorsopathies, not elsewhere classified
0.695 0.304 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.695 0.305 0.000
H33.3 Retinal breaks without detachment
0.694 0.306 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.694 0.306 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.694 0.306 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.694 0.306 0.000
Y44 Agents primarily affecting blood constituents
0.693 0.307 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.692 0.308 0.000
I20.0 Unstable angina
0.692 0.308 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.691 0.309 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.691 0.309 0.000
M93 Other osteochondropathies
0.691 0.309 0.000
S20 Superficial injury of thorax
0.691 0.309 0.000
S09.9 Unspecified injury of head
0.691 0.309 0.000
G61 Inflammatory polyneuropathy
0.691 0.309 0.000
H74 Other disorders of middle ear and mastoid
0.691 0.309 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.690 0.310 0.000
G90 Disorders of autonomic nervous system
0.689 0.311 0.000
H66 Suppurative and unspecified otitis media
0.689 0.311 0.000
K74.4 Secondary biliary cirrhosis
0.689 0.311 0.000
K74.2 Hepatic fibrosis with hepatic sclerosis
0.689 0.311 0.000
K74.1 Hepatic sclerosis
0.689 0.311 0.000
T59 Toxic effect of other gases, fumes and vapours
0.688 0.312 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.688 0.312 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.687 0.313 0.000
H70 Mastoiditis and related conditions
0.687 0.313 0.000
N18.8 Other chronic renal failure
0.686 0.314 0.000
V40-V49 Car occupant injured in transport accident
0.685 0.315 0.000
H18.6 Keratoconus
0.684 0.316 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.684 0.316 0.000
W21.9 Unspecified place
0.683 0.317 0.000
Y59 Other and unspecified vaccines and biological substances
0.682 0.317 0.000
Y58 Bacterial vaccines
0.682 0.317 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.682 0.317 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.682 0.317 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.682 0.317 0.000
Y48 Anaesthetics and therapeutic gases
0.682 0.317 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.682 0.317 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.682 0.317 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.682 0.318 0.000
N17.8 Other acute renal failure
0.682 0.318 0.000
N17.2 Acute renal failure with medullary necrosis
0.682 0.318 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.682 0.318 0.000
N17.0 Acute renal failure with tubular necrosis
0.682 0.318 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.682 0.318 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.682 0.318 0.000
M87 Osteonecrosis
0.681 0.319 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.681 0.319 0.000
M00-M03 Infectious arthropathies
0.681 0.319 0.000
D55-D59 Haemolytic anaemias
0.681 0.319 0.000
Y43.4 Immunosuppressive agents
0.681 0.319 0.000
M86.9 Osteomyelitis, unspecified
0.680 0.320 0.000
S06 Intracranial injury
0.680 0.320 0.000
H04.9 Disorder of lachrymal system, unspecified
0.680 0.320 0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically
0.679 0.321 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.678 0.322 0.000
S26 Injury of heart
0.678 0.322 0.000
S25 Injury of blood vessels of thorax
0.678 0.322 0.000
S24 Injury of nerves and spinal cord at thorax level
0.678 0.322 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.678 0.322 0.000
S21 Open wound of thorax
0.678 0.322 0.000
G64 Other disorders of peripheral nervous system
0.678 0.322 0.000
T90.9 Sequelae of unspecified injury of head
0.678 0.322 0.000
M50.0 Cervical disk disorder with myelopathy
0.677 0.323 0.000
G62.8 Other specified polyneuropathies
0.676 0.324 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.676 0.324 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.676 0.324 0.000
G92 Toxic encephalopathy
0.676 0.324 0.000
I25.6 Silent myocardial ischaemia
0.675 0.324 0.000
I25.4 Coronary artery aneurysm
0.675 0.324 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.675 0.324 0.000
Y89 Sequelae of other external causes
0.675 0.325 0.000
M51.3 Other specified intervertebral disk degeneration
0.674 0.326 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.674 0.326 0.000
M51.4 Schmorl's nodes
0.674 0.326 0.000
M06.0 Seronegative rheumatoid arthritis
0.674 0.326 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.674 0.326 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.672 0.328 0.000
H15 Disorders of sclera
0.672 0.328 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.671 0.329 0.000
T75 Effects of other external causes
0.671 0.329 0.000
T74 Maltreatment syndromes
0.671 0.329 0.000
T73 Effects of other deprivation
0.671 0.329 0.000
T70 Effects of air pressure and water pressure
0.671 0.329 0.000
T69 Other effects of reduced temperature
0.671 0.329 0.000
T67 Effects of heat and light
0.671 0.329 0.000
T71 Asphyxiation
0.671 0.329 0.000
T66 Unspecified effects of radiation
0.671 0.329 0.000
I60 Subarachnoid haemorrhage
0.671 0.329 0.000
D66 Hereditary factor VIII deficiency
0.671 0.329 0.000
G35 Multiple sclerosis
0.670 0.330 0.000
S22.3 Fracture of rib
0.669 0.331 0.000
N11 Chronic tubulo-interstitial nephritis
0.669 0.331 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.667 0.333 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.666 0.334 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.666 0.334 0.000
K75.2 Nonspecific reactive hepatitis
0.666 0.334 0.000
K75.1 Phlebitis of portal vein
0.666 0.334 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.665 0.335 0.000
E16 Other disorders of pancreatic internal secretion
0.664 0.336 0.000
H90.5 Sensorineural hearing loss, unspecified
0.664 0.336 0.000
S27.0 Traumatic pneumothorax
0.663 0.337 0.000
E73 Lactose intolerance
0.663 0.337 0.000
M49 Spondylopathies in diseases classified elsewhere
0.662 0.337 0.000
H25-H28 Disorders of lens
0.661 0.339 0.000
M80 Osteoporosis with pathological fracture
0.661 0.339 0.000
S08 Traumatic amputation of part of head
0.661 0.339 0.000
S07 Crushing injury of head
0.661 0.339 0.000
S04 Injury of cranial nerves
0.661 0.339 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.661 0.339 0.000
I08.0 Disorders of both mitral and aortic valves
0.661 0.339 0.000
H44.2 Degenerative myopia
0.661 0.339 0.000
G96 Other disorders of central nervous system
0.660 0.340 0.000
T98 Sequelae of other and unspecified effects of external causes
0.660 0.340 0.000
T95 Sequelae of burns, corrosions and frostbite
0.660 0.340 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.660 0.340 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.660 0.340 0.000
G70-G73 Diseases of myoneural junction and muscle
0.660 0.340 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.660 0.340 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.659 0.341 0.000
N15 Other renal tubulo-interstitial diseases
0.659 0.341 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.659 0.341 0.000
H80 Otosclerosis
0.659 0.341 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.658 0.342 0.000
B99 Other and unspecified infectious diseases
0.657 0.343 0.000
H91 Other hearing loss
0.657 0.343 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.656 0.344 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.656 0.344 0.000
S60-S69 Injuries to the wrist and hand
0.656 0.344 0.000
N18.1 Chronic kidney disease, stage 1
0.655 0.345 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.655 0.345 0.000
K51.5 Mucosal proctocolitis
0.654 0.345 0.000
I25.5 Ischaemic cardiomyopathy
0.652 0.348 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.652 0.348 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.652 0.348 0.000
Q35-Q37 Cleft lip and cleft palate
0.652 0.348 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.652 0.348 0.000
H04.8 Other disorders of lachrymal system
0.652 0.348 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.652 0.348 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.652 0.348 0.000
A75-A79 Rickettsioses
0.652 0.348 0.000
A70-A74 Other diseases caused by chlamydiae
0.652 0.348 0.000
A20-A28 Certain zoonotic bacterial diseases
0.652 0.348 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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