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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78536404
log Bayes Factor = 15.3069
Chromosome 3   position 29,168,440  (GRCh37) Explore rs78536404 on Ensembl!
Variant rs78536404 is part of Cluster X0047

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.996 0.004 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.995 0.005 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.995 0.005 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.993 0.007 0.000
N30-N39 Other diseases of urinary system
0.992 0.008 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.991 0.009 0.000
Chapter XI Diseases of the digestive system
0.980 0.020 0.000
S00-S09 Injuries to the head
0.976 0.024 0.000
Z95.0 Presence of cardiac pacemaker
0.976 0.024 0.000
N39 Other disorders of urinary system
0.972 0.028 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.968 0.032 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.965 0.035 0.000
T81 Complications of procedures, not elsewhere classified
0.964 0.036 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.959 0.041 0.000
Chapter XX External causes of morbidity and mortality
0.958 0.042 0.000
Chapter I Certain infectious and parasitic diseases
0.956 0.044 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.955 0.045 0.000
I45 Other conduction disorders
0.951 0.049 0.000
Chapter X Diseases of the respiratory system
0.949 0.051 0.000
Z95.2 Presence of prosthetic heart valve
0.948 0.052 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.948 0.052 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.944 0.056 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.943 0.057 0.000
D50-D53 Nutritional anaemias
0.938 0.062 0.000
J95-J99 Other diseases of the respiratory system
0.937 0.063 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.935 0.065 0.000
K50-K52 Noninfective enteritis and colitis
0.935 0.065 0.000
N39.3 Stress incontinence
0.933 0.067 0.000
J98 Other respiratory disorders
0.929 0.071 0.000
S01 Open wound of head
0.928 0.072 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.928 0.072 0.000
Z95.4 Presence of other heart-valve replacement
0.922 0.078 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.922 0.078 0.000
D50 Iron deficiency anaemia
0.920 0.080 0.000
N20-N23 Urolithiasis
0.918 0.082 0.000
K08 Other disorders of teeth and supporting structures
0.917 0.083 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.916 0.084 0.000
J98.1 Pulmonary collapse
0.907 0.093 0.000
S20-S29 Injuries to the thorax
0.906 0.094 0.000
I45.1 Other and unspecified right bundle-branch block
0.904 0.096 0.000
A00-A09 Intestinal infectious diseases
0.903 0.097 0.000
D50.8 Other iron deficiency anaemias
0.899 0.101 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.892 0.108 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.889 0.111 0.000
K50 Crohn's disease [regional enteritis]
0.887 0.113 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.884 0.116 0.000
K70-K77 Diseases of liver
0.882 0.118 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.880 0.120 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.877 0.123 0.000
T39.1 4-Aminophenol derivatives
0.877 0.123 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.877 0.123 0.000
R26 Abnormalities of gait and mobility
0.876 0.124 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.874 0.126 0.000
I31 Other diseases of pericardium
0.874 0.126 0.000
I35 Nonrheumatic aortic valve disorders
0.871 0.128 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.871 0.129 0.000
R21 Rash and other nonspecific skin eruption
0.869 0.131 0.000
N39.0 Urinary tract infection, site not specified
0.868 0.132 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.866 0.134 0.000
S32 Fracture of lumbar spine and pelvis
0.864 0.136 0.000
N25-N29 Other disorders of kidney and ureter
0.862 0.138 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.858 0.142 0.000
Chapter V Mental and behavioural disorders
0.856 0.144 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.853 0.147 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.853 0.147 0.000
S02 Fracture of skull and facial bones
0.852 0.148 0.000
I05-I09 Chronic rheumatic heart diseases
0.851 0.149 0.000
S01.8 Open wound of other parts of head
0.851 0.149 0.000
Z93 Artificial opening status
0.850 0.150 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.850 0.150 0.000
N92 Excessive, frequent and irregular menstruation
0.848 0.152 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.848 0.152 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.846 0.154 0.000
J98.4 Other disorders of lung
0.845 0.155 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.838 0.162 0.000
N60-N64 Disorders of breast
0.838 0.162 0.000
N17-N19 Renal failure
0.837 0.163 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.837 0.163 0.000
K50.9 Crohn's disease, unspecified
0.837 0.163 0.000
Z95.3 Presence of xenogenic heart valve
0.837 0.163 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.836 0.164 0.000
K12 Stomatitis and related lesions
0.835 0.165 0.000
N89 Other noninflammatory disorders of vagina
0.833 0.167 0.000
N20 Calculus of kidney and ureter
0.830 0.170 0.000
R47-R49 Symptoms and signs involving speech and voice
0.830 0.170 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.830 0.170 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.829 0.171 0.000
N30 Cystitis
0.821 0.179 0.000
I46 Cardiac arrest
0.820 0.180 0.000
K51 Ulcerative colitis
0.820 0.180 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.819 0.181 0.000
K02 Dental caries
0.819 0.181 0.000
I33 Acute and subacute endocarditis
0.819 0.181 0.000
Chapter XXII Codes for special purposes
0.818 0.181 0.000
W00-W19 Falls
0.818 0.182 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.816 0.184 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.815 0.185 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.815 0.185 0.000
I38 Endocarditis, valve unspecified
0.812 0.188 0.000
Z94 Transplanted organ and tissue status
0.812 0.188 0.000
Z87 Personal history of other diseases and conditions
0.810 0.190 0.000
I34 Nonrheumatic mitral valve disorders
0.810 0.190 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.809 0.191 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.806 0.194 0.000
A30-A49 Other bacterial diseases
0.806 0.194 0.000
I31.3 Pericardial effusion (noninflammatory)
0.805 0.195 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.804 0.196 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.801 0.199 0.000
N93 Other abnormal uterine and vaginal bleeding
0.800 0.200 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.797 0.203 0.000
S32.0 Fracture of lumbar vertebra
0.797 0.203 0.000
T86 Failure and rejection of transplanted organs and tissues
0.796 0.204 0.000
Z95.1 Presence of aortocoronary bypass graft
0.794 0.206 0.000
N23 Unspecified renal colic
0.793 0.207 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.793 0.207 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.793 0.207 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.792 0.208 0.000
I37 Pulmonary valve disorders
0.791 0.209 0.000
K05 Gingivitis and periodontal diseases
0.791 0.209 0.000
K65-K67 Diseases of peritoneum
0.787 0.213 0.000
K14 Diseases of tongue
0.785 0.215 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.784 0.216 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.783 0.217 0.000
S90-S99 Injuries to the ankle and foot
0.782 0.217 0.000
T79-T79 Certain early complications of trauma
0.782 0.218 0.000
S27 Injury of other and unspecified intrathoracic organs
0.782 0.218 0.000
I60-I69 Cerebrovascular diseases
0.782 0.218 0.000
S70-S79 Injuries to the hip and thigh
0.782 0.218 0.000
K08.3 Retained dental root
0.781 0.219 0.000
N35 Urethral stricture
0.780 0.220 0.000
J90-J94 Other diseases of pleura
0.779 0.221 0.000
I36 Nonrheumatic tricuspid valve disorders
0.778 0.221 0.000
S00 Superficial injury of head
0.774 0.226 0.000
N88 Other noninflammatory disorders of cervix uteri
0.774 0.226 0.000
S01.1 Open wound of eyelid and periocular area
0.772 0.228 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.769 0.231 0.000
S06 Intracranial injury
0.769 0.231 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.768 0.232 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.768 0.232 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.767 0.233 0.000
J00-J06 Acute upper respiratory infections
0.767 0.233 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.766 0.234 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.763 0.237 0.000
K35-K38 Diseases of appendix
0.762 0.238 0.000
K70 Alcoholic liver disease
0.760 0.240 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.759 0.241 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.754 0.246 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.753 0.247 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.752 0.248 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.752 0.248 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.750 0.250 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.750 0.250 0.000
I47 Paroxysmal tachycardia
0.750 0.250 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.750 0.250 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.749 0.251 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.749 0.251 0.000
N84 Polyp of female genital tract
0.746 0.254 0.000
S80-S89 Injuries to the knee and lower leg
0.746 0.254 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.746 0.254 0.000
I27 Other pulmonary heart diseases
0.745 0.255 0.000
I35.9 Aortic valve disorder, unspecified
0.745 0.255 0.000
N87 Dysplasia of cervix uteri
0.744 0.256 0.000
N17 Acute renal failure
0.744 0.256 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.743 0.257 0.000
R26.3 Immobility
0.741 0.259 0.000
N20.1 Calculus of ureter
0.740 0.260 0.000
I45.5 Other specified heart block
0.739 0.261 0.000
I08 Multiple valve diseases
0.739 0.261 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.738 0.262 0.000
T66-T78 Other and unspecified effects of external causes
0.738 0.262 0.000
N00-N08 Glomerular diseases
0.737 0.263 0.000
N64 Other disorders of breast
0.737 0.263 0.000
N92.1 Excessive and frequent menstruation with irregular cycle
0.736 0.264 0.000
Z87.0 Personal history of diseases of the respiratory system
0.735 0.265 0.000
D50.9 Iron deficiency anaemia, unspecified
0.734 0.266 0.000
I44 Atrioventricular and left bundle-branch block
0.732 0.268 0.000
R20 Disturbances of skin sensation
0.731 0.269 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.731 0.269 0.000
Z85 Personal history of malignant neoplasm
0.731 0.269 0.000
R23 Other skin changes
0.729 0.270 0.000
S01.0 Open wound of scalp
0.729 0.271 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.728 0.272 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.728 0.272 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.728 0.272 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.728 0.272 0.000
R27 Other lack of coordination
0.726 0.274 0.000
T43.2 Other and unspecified antidepressants
0.725 0.275 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.723 0.277 0.000
I49 Other cardiac arrhythmias
0.723 0.277 0.000
Z98 Other postsurgical states
0.723 0.277 0.000
R45 Symptoms and signs involving emotional state
0.722 0.278 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.722 0.278 0.000
Z93.3 Colostomy status
0.720 0.280 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.717 0.283 0.000
T87 Complications peculiar to reattachment and amputation
0.716 0.284 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.716 0.284 0.000
S01.3 Open wound of ear
0.715 0.285 0.000
S01.2 Open wound of nose
0.714 0.286 0.000
I52 Other heart disorders in diseases classified elsewhere
0.714 0.286 0.000
I48 Atrial fibrillation and flutter
0.714 0.286 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.714 0.286 0.000
I41 Myocarditis in diseases classified elsewhere
0.714 0.286 0.000
I40 Acute myocarditis
0.714 0.286 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.714 0.286 0.000
I32 Pericarditis in diseases classified elsewhere
0.714 0.286 0.000
I30 Acute pericarditis
0.714 0.286 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.714 0.286 0.000
I45.9 Conduction disorder, unspecified
0.714 0.286 0.000
D80-D89 Certain disorders involving the immune mechanism
0.714 0.286 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.713 0.286 0.000
N39.4 Other specified urinary incontinence
0.713 0.287 0.000
Y95 Nosocomial condition
0.713 0.287 0.000
K02.9 Dental caries, unspecified
0.713 0.287 0.000
S50-S59 Injuries to the elbow and forearm
0.712 0.288 0.000
Z89 Acquired absence of limb
0.712 0.288 0.000
Z84 Family history of other conditions
0.712 0.288 0.000
Z81 Family history of mental and behavioural disorders
0.712 0.288 0.000
N37 Urethral disorders in diseases classified elsewhere
0.711 0.289 0.000
N34 Urethritis and urethral syndrome
0.711 0.289 0.000
N33 Bladder disorders in diseases classified elsewhere
0.711 0.289 0.000
K74 Fibrosis and cirrhosis of liver
0.711 0.289 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.711 0.289 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.711 0.289 0.000
J93 Pneumothorax
0.711 0.289 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.710 0.290 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.710 0.290 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.710 0.290 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.710 0.290 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.710 0.290 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.710 0.290 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.710 0.290 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.710 0.290 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.710 0.290 0.000
T36 Poisoning by systemic antibiotics
0.710 0.290 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.710 0.290 0.000
R94 Abnormal results of function studies
0.709 0.291 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.709 0.291 0.000
R47 Speech disturbances, not elsewhere classified
0.707 0.293 0.000
Y83.8 Other surgical procedures
0.707 0.293 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.707 0.293 0.000
I35.1 Aortic (valve) insufficiency
0.706 0.294 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.704 0.296 0.000
K12.1 Other forms of stomatitis
0.703 0.297 0.000
Z74 Problems related to care-provider dependency
0.703 0.297 0.000
Z97 Presence of other devices
0.702 0.298 0.000
N99-N99 Other disorders of the genitourinary system
0.702 0.298 0.000
K04 Diseases of pulp and periapical tissues
0.702 0.298 0.000
T82.1 Mechanical complication of cardiac electronic device
0.701 0.299 0.000
S08 Traumatic amputation of part of head
0.700 0.300 0.000
S07 Crushing injury of head
0.700 0.300 0.000
S05 Injury of eye and orbit
0.700 0.300 0.000
S04 Injury of cranial nerves
0.700 0.300 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.700 0.300 0.000
N39.8 Other specified disorders of urinary system
0.699 0.301 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.698 0.302 0.000
R25 Abnormal involuntary movements
0.698 0.302 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.698 0.302 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.698 0.302 0.000
N39.2 Orthostatic proteinuria, unspecified
0.697 0.303 0.000
N39.1 Persistent proteinuria, unspecified
0.697 0.303 0.000
R30-R39 Symptoms and signs involving the urinary system
0.697 0.303 0.000
R79 Other abnormal findings of blood chemistry
0.697 0.303 0.000
B15-B19 Viral hepatitis
0.696 0.304 0.000
N80 Endometriosis
0.696 0.304 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.695 0.305 0.000
I42 Cardiomyopathy
0.694 0.305 0.000
N36 Other disorders of urethra
0.694 0.306 0.000
K10 Other diseases of jaws
0.694 0.306 0.000
K09 Cysts of oral region, not elsewhere classified
0.694 0.306 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.694 0.306 0.000
K03 Other diseases of hard tissues of teeth
0.694 0.306 0.000
K00 Disorders of tooth development and eruption
0.694 0.306 0.000
K72 Hepatic failure, not elsewhere classified
0.693 0.306 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.693 0.307 0.000
D55-D59 Haemolytic anaemias
0.692 0.308 0.000
I33.0 Acute and subacute infective endocarditis
0.691 0.309 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.691 0.309 0.000
T81.9 Unspecified complication of procedure
0.691 0.309 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.691 0.309 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.691 0.309 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.691 0.309 0.000
N39.9 Disorder of urinary system, unspecified
0.690 0.310 0.000
K50.1 Crohn's disease of large intestine
0.689 0.311 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.689 0.311 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.687 0.313 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.687 0.313 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.687 0.313 0.000
Y35-Y36 Legal intervention and operations of war
0.687 0.313 0.000
Y10-Y34 Event of undetermined intent
0.687 0.313 0.000
Y00-Y09 Assault
0.687 0.313 0.000
X85-X99 Assault
0.687 0.313 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.687 0.313 0.000
X50-X57 Overexertion, travel and privation
0.687 0.313 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.687 0.313 0.000
X30-X39 Exposure to forces of nature
0.687 0.313 0.000
X20-X29 Contact with venomous animals and plants
0.687 0.313 0.000
X10-X19 Contact with heat and hot substances
0.687 0.313 0.000
X00-X09 Exposure to smoke, fire and flames
0.687 0.313 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.687 0.313 0.000
W75-W84 Other accidental threats to breathing
0.687 0.313 0.000
W65-W74 Accidental drowning and submersion
0.687 0.313 0.000
W50-W64 Exposure to animate mechanical forces
0.687 0.313 0.000
V98-V99 Other and unspecified transport accidents
0.687 0.313 0.000
V95-V97 Air and space transport accidents
0.687 0.313 0.000
V90-V94 Water transport accidents
0.687 0.313 0.000
V80-V89 Other land transport accidents
0.687 0.313 0.000
V70-V79 Bus occupant injured in transport accident
0.687 0.313 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.687 0.313 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.687 0.313 0.000
V40-V49 Car occupant injured in transport accident
0.687 0.313 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.687 0.313 0.000
V01-V09 Pedestrian injured in transport accident
0.687 0.313 0.000
B99-B99 Other infectious diseases
0.685 0.315 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.685 0.315 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.685 0.315 0.000
B65-B83 Helminthiases
0.685 0.315 0.000
B50-B64 Protozoal diseases
0.685 0.315 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.685 0.315 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.685 0.315 0.000
A80-A89 Viral infections of the central nervous system
0.685 0.315 0.000
A75-A79 Rickettsioses
0.685 0.315 0.000
A70-A74 Other diseases caused by chlamydiae
0.685 0.315 0.000
A65-A69 Other spirochaetal diseases
0.685 0.315 0.000
A20-A28 Certain zoonotic bacterial diseases
0.685 0.315 0.000
A15-A19 Tuberculosis
0.685 0.315 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.685 0.315 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.685 0.315 0.000
N98 Complications associated with artificial fertilisation
0.685 0.315 0.000
N91 Absent, scanty and rare menstruation
0.685 0.315 0.000
N82 Fistulae involving female genital tract
0.685 0.315 0.000
N96 Habitual aborter
0.685 0.315 0.000
R22.2 Localised swelling, mass and lump, trunk
0.684 0.316 0.000
K07 Dentofacial anomalies [including malocclusion]
0.683 0.316 0.000
V20-V29 Motorcycle rider injured in transport accident
0.683 0.317 0.000
S02.4 Fracture of malar and maxillary bones
0.683 0.317 0.000
S32.5 Fracture of pubis
0.683 0.317 0.000
Q50-Q56 Congenital malformations of genital organs
0.682 0.318 0.000
I45.8 Other specified conduction disorders
0.682 0.318 0.000
I45.6 Preexcitation syndrome
0.682 0.318 0.000
I45.4 Nonspecific intraventricular block
0.682 0.318 0.000
I45.3 Trifascicular block
0.682 0.318 0.000
I45.2 Bifascicular block
0.682 0.318 0.000
I45.0 Right fascicular block
0.682 0.318 0.000
D60-D64 Aplastic and other anaemias
0.682 0.318 0.000
Q60-Q64 Congenital malformations of the urinary system
0.682 0.318 0.000
I34.1 Mitral (valve) prolapse
0.681 0.319 0.000
K11 Diseases of salivary glands
0.680 0.320 0.000
T85.2 Mechanical complication of intraocular lens
0.680 0.320 0.000
B25-B34 Other viral diseases
0.680 0.320 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.680 0.320 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.680 0.320 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.680 0.320 0.000
T82.3 Mechanical complication of other vascular grafts
0.680 0.320 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.680 0.320 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.680 0.320 0.000
X60-X84 Intentional self-harm
0.679 0.321 0.000
W10 Fall on and from stairs and steps
0.679 0.321 0.000
F17.1 Harmful use
0.679 0.321 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.678 0.322 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.678 0.322 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.677 0.323 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.677 0.323 0.000
N17.9 Acute renal failure, unspecified
0.677 0.323 0.000
S02.3 Fracture of orbital floor
0.677 0.323 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.677 0.323 0.000
I10-I15 Hypertensive diseases
0.677 0.323 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.676 0.324 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.676 0.324 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.676 0.324 0.000
T39.4 Antirheumatics, not elsewhere classified
0.676 0.324 0.000
T39.2 Pyrazolone derivatives
0.676 0.324 0.000
T39.0 Salicylates
0.676 0.324 0.000
Z45 Adjustment and management of implanted device
0.676 0.324 0.000
R32 Unspecified urinary incontinence
0.674 0.326 0.000
I46.0 Cardiac arrest with successful resuscitation
0.674 0.326 0.000
D53 Other nutritional anaemias
0.672 0.327 0.000
D52 Folate deficiency anaemia
0.672 0.327 0.000
W20-W49 Exposure to inanimate mechanical forces
0.672 0.328 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.672 0.328 0.000
J96 Respiratory failure, not elsewhere classified
0.672 0.328 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.672 0.328 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.672 0.328 0.000
J40-J47 Chronic lower respiratory diseases
0.671 0.329 0.000
S40-S49 Injuries to the shoulder and upper arm
0.670 0.330 0.000
S02.2 Fracture of nasal bones
0.670 0.330 0.000
V10-V19 Pedal cyclist injured in transport accident
0.670 0.330 0.000
Z75 Problems related to medical facilities and other health care
0.669 0.331 0.000
K50.0 Crohn's disease of small intestine
0.668 0.332 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.668 0.332 0.000
N30.2 Other chronic cystitis
0.668 0.332 0.000
N10-N16 Renal tubulo-interstitial diseases
0.666 0.334 0.000
N89.5 Stricture and atresia of vagina
0.666 0.334 0.000
K75 Other inflammatory liver diseases
0.666 0.334 0.000
J98.9 Respiratory disorder, unspecified
0.666 0.334 0.000
J98.8 Other specified respiratory disorders
0.666 0.334 0.000
J98.6 Disorders of diaphragm
0.666 0.334 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.666 0.334 0.000
J98.3 Compensatory emphysema
0.666 0.334 0.000
J98.2 Interstitial emphysema
0.666 0.334 0.000
N94.1 Dyspareunia
0.666 0.334 0.000
S01.7 Multiple open wounds of head
0.665 0.335 0.000
S01.4 Open wound of cheek and temporomandibular area
0.665 0.335 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.665 0.335 0.000
S37 Injury of urinary and pelvic organs
0.665 0.335 0.000
S36 Injury of intra-abdominal organs
0.665 0.335 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.665 0.335 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.665 0.335 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.665 0.335 0.000
S31 Open wound of abdomen, lower back and pelvis
0.665 0.335 0.000
N97 Female infertility
0.664 0.336 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.664 0.336 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.664 0.336 0.000
A49 Bacterial infection of unspecified site
0.663 0.337 0.000
D70 Agranulocytosis
0.663 0.337 0.000
R76 Other abnormal immunological findings in serum
0.661 0.339 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.661 0.339 0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.661 0.339 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.660 0.339 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.660 0.340 0.000
K01 Embedded and impacted teeth
0.660 0.340 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.660 0.340 0.000
D50.1 Sideropenic dysphagia
0.659 0.340 0.000
S27.0 Traumatic pneumothorax
0.659 0.341 0.000
N30.0 Acute cystitis
0.658 0.342 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.658 0.342 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.658 0.342 0.000
Z93.2 Ileostomy status
0.658 0.342 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.657 0.343 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.657 0.343 0.000
K08.0 Exfoliation of teeth due to systemic causes
0.657 0.343 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.657 0.343 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.657 0.343 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.657 0.343 0.000
R03.1 Nonspecific low blood-pressure reading
0.656 0.344 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.656 0.344 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.655 0.345 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.655 0.345 0.000
R73 Elevated blood glucose level
0.655 0.345 0.000
Z99.8 Dependence on other enabling machines and devices
0.654 0.346 0.000
Z60 Problems related to social environment
0.653 0.347 0.000
Z94.4 Liver transplant status
0.653 0.347 0.000
D51 Vitamin B12 deficiency anaemia
0.653 0.347 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.651 0.349 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.651 0.349 0.000
Chapter II Neoplasms
0.651 0.349 0.000
R22.0 Localised swelling, mass and lump, head
0.651 0.349 0.000
R00 Abnormalities of heart beat
0.651 0.349 0.000
T86.0 Bone-marrow transplant rejection
0.650 0.349 0.000
W19 Unspecified fall
0.650 0.350 0.000
S29 Other and unspecified injuries of thorax
0.650 0.350 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.650 0.350 0.000
S26 Injury of heart
0.650 0.350 0.000
S25 Injury of blood vessels of thorax
0.650 0.350 0.000
S24 Injury of nerves and spinal cord at thorax level
0.650 0.350 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.650 0.350 0.000
S21 Open wound of thorax
0.650 0.350 0.000
S20 Superficial injury of thorax
0.650 0.350 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.649 0.351 0.000
Z94.8 Other transplanted organ and tissue status
0.649 0.351 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.647 0.353 0.000
A07 Other protozoal intestinal diseases
0.647 0.353 0.000
A06 Amoebiasis
0.647 0.353 0.000
A05 Other bacterial foodborne intoxications
0.647 0.353 0.000
A03 Shigellosis
0.647 0.353 0.000
A02 Other Salmonella infections
0.647 0.353 0.000
A01 Typhoid and paratyphoid fevers
0.647 0.353 0.000
A00 Cholera
0.647 0.353 0.000
I27.0 Primary pulmonary hypertension
0.647 0.353 0.000
I69 Sequelae of cerebrovascular disease
0.646 0.354 0.000
N88.8 Other specified noninflammatory disorders of cervix uteri
0.645 0.355 0.000
I37.1 Pulmonary valve insufficiency
0.644 0.356 0.000
N84.0 Polyp of corpus uteri
0.644 0.356 0.000
J60-J70 Lung diseases due to external agents
0.643 0.357 0.000
K05.1 Chronic gingivitis
0.642 0.358 0.000
I05 Rheumatic mitral valve diseases
0.641 0.358 0.000
B35-B49 Mycoses
0.641 0.359 0.000
N20.0 Calculus of kidney
0.640 0.360 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.639 0.361 0.000
S22.3 Fracture of rib
0.639 0.361 0.000
N90.7 Vulvar cyst
0.639 0.361 0.000
J09-J18 Influenza and pneumonia
0.638 0.362 0.000
K65 Peritonitis
0.638 0.362 0.000
R47.0 Dysphasia and aphasia
0.637 0.363 0.000
T50.8 Diagnostic agents
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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