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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78554755
log Bayes Factor = 16.3804
Chromosome 10   position 45,343,576  (GRCh37) Explore rs78554755 on Ensembl!
Variant rs78554755 is part of Cluster X0145

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
K29 Gastritis and duodenitis
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
N30-N39 Other diseases of urinary system
0.994 0.006 0.000
I30-I52 Other forms of heart disease
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.990 0.010 0.000
N60-N64 Disorders of breast
0.983 0.017 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.983 0.017 0.000
N39 Other disorders of urinary system
0.982 0.018 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.980 0.020 0.000
I10-I15 Hypertensive diseases
0.980 0.020 0.000
M20-M25 Other joint disorders
0.978 0.022 0.000
K29.7 Gastritis, unspecified
0.977 0.023 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.976 0.024 0.000
K21 Gastro-oesophageal reflux disease
0.972 0.028 0.000
N39.0 Urinary tract infection, site not specified
0.964 0.036 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.959 0.041 0.000
N39.4 Other specified urinary incontinence
0.958 0.042 0.000
I10 Essential (primary) hypertension
0.956 0.044 0.000
K29.8 Duodenitis
0.952 0.048 0.000
K31 Other diseases of stomach and duodenum
0.950 0.050 0.000
K86 Other diseases of pancreas
0.949 0.051 0.000
S60-S69 Injuries to the wrist and hand
0.948 0.052 0.000
N62 Hypertrophy of breast
0.945 0.055 0.000
M20 Acquired deformities of fingers and toes
0.939 0.061 0.000
I84 Haemorrhoids
0.938 0.062 0.000
K81 Cholecystitis
0.929 0.071 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.928 0.072 0.000
K29.5 Chronic gastritis, unspecified
0.926 0.074 0.000
N10-N16 Renal tubulo-interstitial diseases
0.924 0.076 0.000
N17-N19 Renal failure
0.924 0.076 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.922 0.078 0.000
K22 Other diseases of oesophagus
0.922 0.078 0.000
Chapter XXII Codes for special purposes
0.920 0.080 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.919 0.081 0.000
I84.8 Unspecified haemorrhoids with other complications
0.919 0.081 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.918 0.082 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.913 0.087 0.000
K31.8 Other specified diseases of stomach and duodenum
0.910 0.090 0.000
Chapter V Mental and behavioural disorders
0.907 0.093 0.000
I45 Other conduction disorders
0.907 0.093 0.000
M70-M79 Other soft tissue disorders
0.892 0.108 0.000
N25-N29 Other disorders of kidney and ureter
0.890 0.110 0.000
I60-I69 Cerebrovascular diseases
0.890 0.110 0.000
Chapter II Neoplasms
0.890 0.110 0.000
K81.1 Chronic cholecystitis
0.885 0.115 0.000
I44 Atrioventricular and left bundle-branch block
0.884 0.116 0.000
Chapter VIII Diseases of the ear and mastoid process
0.884 0.116 0.000
M20.2 Hallux rigidus
0.883 0.117 0.000
F30-F39 Mood [affective] disorders
0.882 0.118 0.000
I51 Complications and ill-defined descriptions of heart disease
0.881 0.119 0.000
N17 Acute renal failure
0.876 0.124 0.000
K35-K38 Diseases of appendix
0.874 0.126 0.000
K29.4 Chronic atrophic gastritis
0.874 0.126 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.871 0.129 0.000
I47 Paroxysmal tachycardia
0.867 0.133 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.866 0.134 0.000
Chapter I Certain infectious and parasitic diseases
0.864 0.136 0.000
K86.1 Other chronic pancreatitis
0.863 0.137 0.000
I95 Hypotension
0.863 0.137 0.000
N13 Obstructive and reflux uropathy
0.863 0.137 0.000
N64 Other disorders of breast
0.863 0.137 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.862 0.138 0.000
I84.9 Unspecified haemorrhoids without complication
0.859 0.141 0.000
N63 Unspecified lump in breast
0.858 0.142 0.000
I50 Heart failure
0.855 0.145 0.000
N30 Cystitis
0.855 0.145 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.853 0.147 0.000
I42 Cardiomyopathy
0.853 0.147 0.000
K30 Dyspepsia
0.852 0.148 0.000
M20.1 Hallux valgus (acquired)
0.850 0.150 0.000
I87 Other disorders of veins
0.848 0.152 0.000
K22.2 Oesophageal obstruction
0.848 0.152 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.848 0.152 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.847 0.153 0.000
M22 Disorders of patella
0.846 0.154 0.000
W20-W49 Exposure to inanimate mechanical forces
0.845 0.155 0.000
M23 Internal derangement of knee
0.843 0.157 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.842 0.158 0.000
W00-W19 Falls
0.841 0.159 0.000
S00-S09 Injuries to the head
0.839 0.161 0.000
N35 Urethral stricture
0.839 0.161 0.000
F32 Depressive episode
0.838 0.162 0.000
Chapter VI Diseases of the nervous system
0.835 0.165 0.000
L60-L75 Disorders of skin appendages
0.835 0.165 0.000
K55-K64 Other diseases of intestines
0.834 0.166 0.000
S90-S99 Injuries to the ankle and foot
0.829 0.171 0.000
Y52 Agents primarily affecting the cardiovascular system
0.828 0.172 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.827 0.173 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.827 0.173 0.000
T39.1 4-Aminophenol derivatives
0.826 0.174 0.000
N17.9 Acute renal failure, unspecified
0.822 0.178 0.000
K29.3 Chronic superficial gastritis
0.820 0.180 0.000
R50-R69 General symptoms and signs
0.818 0.182 0.000
I15 Secondary hypertension
0.815 0.184 0.000
I05-I09 Chronic rheumatic heart diseases
0.815 0.185 0.000
S20-S29 Injuries to the thorax
0.814 0.186 0.000
I95.9 Hypotension, unspecified
0.814 0.186 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.811 0.189 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.811 0.189 0.000
I51.7 Cardiomegaly
0.811 0.189 0.000
R63 Symptoms and signs concerning food and fluid intake
0.810 0.190 0.000
K35 Acute appendicitis
0.810 0.190 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.810 0.190 0.000
K26 Duodenal ulcer
0.809 0.191 0.000
M20.3 Other deformity of hallux (acquired)
0.809 0.191 0.000
S60 Superficial injury of wrist and hand
0.807 0.193 0.000
F31 Bipolar affective disorder
0.806 0.194 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.806 0.194 0.000
M86-M90 Other osteopathies
0.801 0.199 0.000
N36 Other disorders of urethra
0.799 0.201 0.000
K63 Other diseases of intestine
0.799 0.201 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.798 0.202 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.796 0.204 0.000
X60-X84 Intentional self-harm
0.795 0.205 0.000
F32.9 Depressive episode, unspecified
0.794 0.206 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.793 0.207 0.000
M80-M85 Disorders of bone density and structure
0.793 0.207 0.000
M79.8 Other specified soft tissue disorders
0.792 0.208 0.000
K29.1 Other acute gastritis
0.791 0.208 0.000
M24 Other specific joint derangements
0.791 0.209 0.000
R63.4 Abnormal weight loss
0.790 0.210 0.000
I45.9 Conduction disorder, unspecified
0.789 0.211 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.787 0.213 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.787 0.213 0.000
S67 Crushing injury of wrist and hand
0.787 0.213 0.000
H90-H95 Other disorders of ear
0.785 0.215 0.000
B95-B98 Bacterial, viral and other infectious agents
0.785 0.215 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.785 0.215 0.000
K63.5 Polyp of colon
0.782 0.218 0.000
K86.2 Cyst of pancreas
0.781 0.219 0.000
I31 Other diseases of pericardium
0.776 0.224 0.000
N00-N08 Glomerular diseases
0.775 0.224 0.000
M79.0 Rheumatism, unspecified
0.775 0.225 0.000
I50.1 Left ventricular failure
0.774 0.226 0.000
K60 Fissure and fistula of anal and rectal regions
0.773 0.227 0.000
I45.1 Other and unspecified right bundle-branch block
0.773 0.227 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.773 0.227 0.000
M21 Other acquired deformities of limbs
0.771 0.229 0.000
I44.7 Left bundle-branch block, unspecified
0.768 0.232 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.767 0.233 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.764 0.236 0.000
K22.4 Dyskinesia of oesophagus
0.763 0.237 0.000
K35.9 Acute appendicitis, unspecified
0.762 0.238 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.760 0.240 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.760 0.240 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.758 0.242 0.000
K86.8 Other specified diseases of pancreas
0.755 0.244 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.755 0.245 0.000
I26 Pulmonary embolism
0.755 0.245 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.754 0.246 0.000
I82 Other venous embolism and thrombosis
0.753 0.247 0.000
M25 Other joint disorders, not elsewhere classified
0.752 0.248 0.000
Y57 Other and unspecified drugs and medicaments
0.752 0.248 0.000
M22.4 Chondromalacia patellae
0.751 0.248 0.000
T66-T78 Other and unspecified effects of external causes
0.751 0.249 0.000
I47.1 Supraventricular tachycardia
0.748 0.252 0.000
M31 Other necrotising vasculopathies
0.747 0.253 0.000
I87.1 Compression of vein
0.747 0.253 0.000
L50-L54 Urticaria and erythema
0.744 0.256 0.000
M91-M94 Chondropathies
0.743 0.256 0.000
M23.3 Other meniscus derangements
0.743 0.257 0.000
K82 Other diseases of gallbladder
0.743 0.257 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.742 0.258 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.742 0.258 0.000
N28.8 Other specified disorders of kidney and ureter
0.741 0.259 0.000
V80-V89 Other land transport accidents
0.740 0.260 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.739 0.261 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.739 0.261 0.000
I61 Intracerebral haemorrhage
0.737 0.263 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.737 0.263 0.000
M34 Systemic sclerosis
0.737 0.263 0.000
S00 Superficial injury of head
0.736 0.264 0.000
M23.8 Other internal derangements of knee
0.735 0.265 0.000
K86.9 Disease of pancreas, unspecified
0.734 0.266 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.734 0.266 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.734 0.266 0.000
I86 Varicose veins of other sites
0.733 0.267 0.000
Y40 Systemic antibiotics
0.730 0.270 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.730 0.270 0.000
S68 Traumatic amputation of wrist and hand
0.730 0.270 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.730 0.270 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.728 0.272 0.000
N18 Chronic renal failure
0.728 0.272 0.000
L90 Atrophic disorders of skin
0.728 0.272 0.000
K22.7 Barrett's oesophagus
0.728 0.272 0.000
T39.0 Salicylates
0.727 0.273 0.000
N35.9 Urethral stricture, unspecified
0.727 0.273 0.000
N64.9 Disorder of breast, unspecified
0.727 0.273 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.726 0.274 0.000
H65-H75 Diseases of middle ear and mastoid
0.726 0.274 0.000
H90 Conductive and sensorineural hearing loss
0.724 0.276 0.000
L82 Seborrhoeic keratosis
0.724 0.276 0.000
I33 Acute and subacute endocarditis
0.723 0.277 0.000
I42.9 Cardiomyopathy, unspecified
0.722 0.278 0.000
I50.9 Heart failure, unspecified
0.722 0.278 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.721 0.279 0.000
N17.0 Acute renal failure with tubular necrosis
0.721 0.279 0.000
N99-N99 Other disorders of the genitourinary system
0.720 0.280 0.000
S62 Fracture at wrist and hand level
0.719 0.280 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.719 0.281 0.000
R63.0 Anorexia
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
K28 Gastrojejunal ulcer
0.717 0.283 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
L20-L30 Dermatitis and eczema
0.717 0.283 0.000
K29.9 Gastroduodenitis, unspecified
0.716 0.284 0.000
K29.2 Alcoholic gastritis
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.715 0.285 0.000
I45.5 Other specified heart block
0.714 0.286 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.714 0.286 0.000
I63 Cerebral infarction
0.714 0.286 0.000
W07 Fall involving chair
0.713 0.287 0.000
N37 Urethral disorders in diseases classified elsewhere
0.712 0.287 0.000
N34 Urethritis and urethral syndrome
0.712 0.287 0.000
N33 Bladder disorders in diseases classified elsewhere
0.712 0.287 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.712 0.288 0.000
I52 Other heart disorders in diseases classified elsewhere
0.712 0.288 0.000
I48 Atrial fibrillation and flutter
0.712 0.288 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.712 0.288 0.000
I41 Myocarditis in diseases classified elsewhere
0.712 0.288 0.000
I40 Acute myocarditis
0.712 0.288 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.712 0.288 0.000
I37 Pulmonary valve disorders
0.712 0.288 0.000
I36 Nonrheumatic tricuspid valve disorders
0.712 0.288 0.000
I32 Pericarditis in diseases classified elsewhere
0.712 0.288 0.000
L81 Other disorders of pigmentation
0.712 0.288 0.000
S61 Open wound of wrist and hand
0.712 0.288 0.000
I46 Cardiac arrest
0.711 0.288 0.000
I11 Hypertensive heart disease
0.711 0.289 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.711 0.289 0.000
N30.9 Cystitis, unspecified
0.711 0.289 0.000
K85 Acute pancreatitis
0.710 0.289 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.710 0.290 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.709 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.290 0.000
Y10-Y34 Event of undetermined intent
0.709 0.290 0.000
Y00-Y09 Assault
0.709 0.290 0.000
X85-X99 Assault
0.709 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.290 0.000
X50-X57 Overexertion, travel and privation
0.709 0.290 0.000
X30-X39 Exposure to forces of nature
0.709 0.290 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.290 0.000
X10-X19 Contact with heat and hot substances
0.709 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.290 0.000
W75-W84 Other accidental threats to breathing
0.709 0.290 0.000
W65-W74 Accidental drowning and submersion
0.709 0.290 0.000
W50-W64 Exposure to animate mechanical forces
0.709 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.290 0.000
V95-V97 Air and space transport accidents
0.709 0.290 0.000
V90-V94 Water transport accidents
0.709 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.290 0.000
V40-V49 Car occupant injured in transport accident
0.709 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.290 0.000
V20-V29 Motorcycle rider injured in transport accident
0.709 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.290 0.000
I30 Acute pericarditis
0.708 0.292 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.707 0.293 0.000
M20.0 Deformity of finger(s)
0.707 0.293 0.000
I38 Endocarditis, valve unspecified
0.707 0.293 0.000
I67 Other cerebrovascular diseases
0.706 0.294 0.000
T79-T79 Certain early complications of trauma
0.705 0.295 0.000
R47-R49 Symptoms and signs involving speech and voice
0.705 0.295 0.000
M60-M63 Disorders of muscles
0.705 0.295 0.000
M00-M03 Infectious arthropathies
0.705 0.295 0.000
N39.2 Orthostatic proteinuria, unspecified
0.704 0.296 0.000
N39.1 Persistent proteinuria, unspecified
0.704 0.296 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.704 0.296 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.703 0.297 0.000
N61 Inflammatory disorders of breast
0.703 0.297 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.703 0.297 0.000
I13 Hypertensive heart and renal disease
0.702 0.297 0.000
N30.2 Other chronic cystitis
0.702 0.298 0.000
G20-G26 Extrapyramidal and movement disorders
0.702 0.298 0.000
U80 Agent resistant to penicillin and related antibiotics
0.701 0.298 0.000
O60-O75 Complications of labour and delivery
0.701 0.299 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.701 0.299 0.000
M33 Dermatopolymyositis
0.701 0.299 0.000
M32 Systemic lupus erythematosus
0.701 0.299 0.000
M30 Polyarteritis nodosa and related conditions
0.701 0.299 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.701 0.299 0.000
C15-C26 Malignant neoplasms of digestive organs
0.700 0.300 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.700 0.300 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.700 0.300 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.700 0.300 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.700 0.300 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.700 0.300 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.700 0.300 0.000
T36 Poisoning by systemic antibiotics
0.700 0.300 0.000
I44.2 Atrioventricular block, complete
0.699 0.301 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.699 0.301 0.000
N30.3 Trigonitis
0.699 0.301 0.000
K22.8 Other specified diseases of oesophagus
0.699 0.301 0.000
N20-N23 Urolithiasis
0.699 0.301 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.699 0.301 0.000
S06 Intracranial injury
0.698 0.302 0.000
I15.1 Hypertension secondary to other renal disorders
0.698 0.302 0.000
K81.9 Cholecystitis, unspecified
0.696 0.303 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.696 0.304 0.000
I62 Other nontraumatic intracranial haemorrhage
0.696 0.304 0.000
I95.2 Hypotension due to drugs
0.694 0.305 0.000
K22.0 Achalasia of cardia
0.694 0.305 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.694 0.306 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.694 0.306 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.694 0.306 0.000
I84.6 Residual haemorrhoidal skin tags
0.694 0.306 0.000
T42.4 Benzodiazepines
0.694 0.306 0.000
R59 Enlarged lymph nodes
0.693 0.307 0.000
K63.1 Perforation of intestine (nontraumatic)
0.692 0.308 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.690 0.310 0.000
S64 Injury of nerves at wrist and hand level
0.690 0.310 0.000
W44 Foreign body entering into or through eye or natural orifice
0.690 0.310 0.000
V10-V19 Pedal cyclist injured in transport accident
0.690 0.310 0.000
S70-S79 Injuries to the hip and thigh
0.689 0.311 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.689 0.311 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.689 0.311 0.000
N13.4 Hydroureter
0.689 0.311 0.000
I88 Nonspecific lymphadenitis
0.687 0.313 0.000
B15-B19 Viral hepatitis
0.687 0.313 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.687 0.313 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.687 0.313 0.000
I51.8 Other ill-defined heart diseases
0.687 0.313 0.000
W25 Contact with sharp glass
0.686 0.313 0.000
I12 Hypertensive renal disease
0.686 0.314 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.686 0.314 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.685 0.315 0.000
K81.0 Acute cholecystitis
0.684 0.316 0.000
G40-G47 Episodic and paroxysmal disorders
0.684 0.316 0.000
T46.1 Calcium-channel blockers
0.684 0.316 0.000
K36 Other appendicitis
0.683 0.317 0.000
K57 Diverticular disease of intestine
0.683 0.317 0.000
I47.2 Ventricular tachycardia
0.682 0.318 0.000
L60 Nail disorders
0.682 0.318 0.000
L73 Other follicular disorders
0.682 0.318 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.681 0.319 0.000
K31.6 Fistula of stomach and duodenum
0.681 0.319 0.000
K31.5 Obstruction of duodenum
0.681 0.319 0.000
K31.4 Gastric diverticulum
0.681 0.319 0.000
K31.3 Pylorospasm, not elsewhere classified
0.681 0.319 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.681 0.319 0.000
K31.0 Acute dilatation of stomach
0.681 0.319 0.000
K83 Other diseases of biliary tract
0.680 0.320 0.000
S69 Other and unspecified injuries of wrist and hand
0.680 0.320 0.000
S65 Injury of blood vessels at wrist and hand level
0.680 0.320 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.680 0.320 0.000
S50-S59 Injuries to the elbow and forearm
0.678 0.322 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.678 0.322 0.000
K86.3 Pseudocyst of pancreas
0.677 0.323 0.000
Q60-Q64 Congenital malformations of the urinary system
0.677 0.323 0.000
S20 Superficial injury of thorax
0.677 0.323 0.000
I07 Rheumatic tricuspid valve diseases
0.676 0.324 0.000
I81 Portal vein thrombosis
0.675 0.325 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.675 0.325 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.674 0.326 0.000
K60.2 Anal fissure, unspecified
0.673 0.327 0.000
N64.5 Other signs and symptoms in breast
0.672 0.328 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.672 0.328 0.000
I84.0 Internal thrombosed haemorrhoids
0.672 0.328 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.672 0.328 0.000
S67.0 Crushing injury of thumb and other finger(s)
0.671 0.329 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.669 0.331 0.000
C80 Malignant neoplasm without specification of site
0.668 0.331 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.668 0.332 0.000
K60.3 Anal fistula
0.668 0.332 0.000
M88 Paget's disease of bone [osteitis deformans]
0.668 0.332 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.667 0.333 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.667 0.333 0.000
K81.8 Other cholecystitis
0.666 0.334 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.666 0.334 0.000
L10-L14 Bullous disorders
0.665 0.334 0.000
M72 Fibroblastic disorders
0.663 0.336 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.663 0.337 0.000
N15 Other renal tubulo-interstitial diseases
0.663 0.337 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.663 0.337 0.000
N11 Chronic tubulo-interstitial nephritis
0.663 0.337 0.000
N10 Acute tubulo-interstitial nephritis
0.663 0.337 0.000
W13 Fall from, out of or through building or structure
0.661 0.338 0.000
Y59 Other and unspecified vaccines and biological substances
0.661 0.339 0.000
Y58 Bacterial vaccines
0.661 0.339 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.661 0.339 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.661 0.339 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.661 0.339 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.661 0.339 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.661 0.339 0.000
Y48 Anaesthetics and therapeutic gases
0.661 0.339 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.661 0.339 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.661 0.339 0.000
Y44 Agents primarily affecting blood constituents
0.661 0.339 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.661 0.339 0.000
K22.5 Diverticulum of oesophagus, acquired
0.661 0.339 0.000
K22.3 Perforation of oesophagus
0.661 0.339 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.661 0.339 0.000
I87.2 Venous insufficiency (chronic) (peripheral)
0.661 0.339 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.660 0.340 0.000
I84.2 Internal haemorrhoids without complication
0.660 0.340 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.660 0.340 0.000
T63 Toxic effect of contact with venomous animals
0.659 0.341 0.000
M40-M43 Deforming dorsopathies
0.659 0.341 0.000
Y43 Primarily systemic agents
0.659 0.341 0.000
R56 Convulsions, not elsewhere classified
0.659 0.341 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.659 0.341 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.658 0.342 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.658 0.342 0.000
T39.4 Antirheumatics, not elsewhere classified
0.658 0.342 0.000
T39.2 Pyrazolone derivatives
0.658 0.342 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.657 0.343 0.000
N13.8 Other obstructive and reflux uropathy
0.656 0.344 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.656 0.344 0.000
D10-D36 Benign neoplasms
0.656 0.344 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.656 0.344 0.000
S99 Other and unspecified injuries of ankle and foot
0.655 0.345 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.655 0.345 0.000
I99 Other and unspecified disorders of circulatory system
0.655 0.345 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.653 0.347 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.653 0.347 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.652 0.348 0.000
W29 Contact with other powered hand tools and household machinery
0.651 0.349 0.000
N30.0 Acute cystitis
0.651 0.349 0.000
I60 Subarachnoid haemorrhage
0.651 0.349 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.651 0.349 0.000
H60-H62 Diseases of external ear
0.651 0.349 0.000
F99-F99 Unspecified mental disorder
0.650 0.349 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.650 0.349 0.000
F70-F79 Mental retardation
0.650 0.349 0.000
F60-F69 Disorders of adult personality and behaviour
0.650 0.349 0.000
I45.8 Other specified conduction disorders
0.650 0.350 0.000
I45.4 Nonspecific intraventricular block
0.650 0.350 0.000
I45.3 Trifascicular block
0.650 0.350 0.000
I45.2 Bifascicular block
0.650 0.350 0.000
I45.0 Right fascicular block
0.650 0.350 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.649 0.351 0.000
K35.1 Acute appendicitis with peritoneal abscess
0.649 0.351 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.649 0.351 0.000
T17 Foreign body in respiratory tract
0.649 0.351 0.000
I44.0 Atrioventricular block, first degree
0.647 0.353 0.000
L50 Urticaria
0.647 0.353 0.000
C60-C63 Malignant neoplasms of male genital organs
0.647 0.353 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.645 0.355 0.000
F80-F89 Disorders of psychological development
0.645 0.355 0.000
I69 Sequelae of cerebrovascular disease
0.645 0.355 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.644 0.356 0.000
K29.0 Acute haemorrhagic gastritis
0.644 0.356 0.000
N64.8 Other specified disorders of breast
0.644 0.356 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.644 0.356 0.000
Y83.6 Removal of other organ (partial) (total)
0.643 0.357 0.000
I44.1 Atrioventricular block, second degree
0.643 0.357 0.000
M21.0 Valgus deformity, not elsewhere classified
0.643 0.357 0.000
U51 Admission status on psychiatric patients
0.642 0.358 0.000
N36.3 Prolapsed urethral mucosa
0.642 0.358 0.000
N64.1 Fat necrosis of breast
0.642 0.358 0.000
S60.8 Other superficial injuries of wrist and hand
0.641 0.359 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.641 0.359 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.640 0.359 0.000
M84 Disorders of continuity of bone
0.640 0.360 0.000
N02 Recurrent and persistent haematuria
0.639 0.360 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.639 0.361 0.000
L90.0 Lichen sclerosus et atrophicus
0.639 0.361 0.000
U89 Agent resistant to other and unspecified antibiotics
0.639 0.361 0.000
M76 Enthesopathies of lower limb, excluding foot
0.639 0.361 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.639 0.361 0.000
M71 Other bursopathies
0.639 0.361 0.000
S29 Other and unspecified injuries of thorax
0.639 0.361 0.000
I82.2 Embolism and thrombosis of vena cava
0.639 0.361 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.638 0.361 0.000
M80 Osteoporosis with pathological fracture
0.638 0.362 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.638 0.362 0.000
N27 Small kidney of unknown cause
0.638 0.362 0.000
N25 Disorders resulting from impaired renal tubular function
0.638 0.362 0.000
N26 Unspecified contracted kidney
0.638 0.362 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.638 0.362 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.638 0.362 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.638 0.362 0.000
S00.8 Superficial injury of other parts of head
0.638 0.362 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.638 0.362 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.638 0.362 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.638 0.362 0.000
S02 Fracture of skull and facial bones
0.638 0.362 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.638 0.362 0.000
N28.1 Cyst of kidney, acquired
0.638 0.362 0.000
I84.3 External thrombosed haemorrhoids
0.637 0.363 0.000
U88 Agent resistant to multiple antibiotics
0.636 0.363 0.000
I27 Other pulmonary heart diseases
0.636 0.364 0.000
N21 Calculus of lower urinary tract
0.635 0.365 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.635 0.365 0.000
N36.8 Other specified disorders of urethra
0.635 0.365 0.000
Q50-Q56 Congenital malformations of genital organs
0.635 0.365 0.000
H91 Other hearing loss
0.635 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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