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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78714450
log Bayes Factor = 5.15716
Chromosome 15   position 86,788,684  (GRCh37) Explore rs78714450 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
C15-C26 Malignant neoplasms of digestive organs
0.999 0.001 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.999 0.001 0.000
C18 Malignant neoplasm of colon
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
D70 Agranulocytosis
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.996 0.004 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.992 0.008 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.989 0.011 0.000
Chapter VIII Diseases of the ear and mastoid process
0.988 0.012 0.000
Chapter I Certain infectious and parasitic diseases
0.988 0.012 0.000
C18.4 Transverse colon
0.985 0.015 0.000
C64-C68 Malignant neoplasms of urinary tract
0.984 0.016 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.981 0.019 0.000
C67 Malignant neoplasm of bladder
0.978 0.022 0.000
H90-H95 Other disorders of ear
0.973 0.027 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.967 0.033 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.964 0.036 0.000
Y43 Primarily systemic agents
0.953 0.047 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.948 0.052 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.940 0.060 0.000
Y43.3 Other antineoplastic drugs
0.937 0.063 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.937 0.063 0.000
W20-W49 Exposure to inanimate mechanical forces
0.934 0.066 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.934 0.066 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.932 0.068 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.929 0.071 0.000
H91 Other hearing loss
0.929 0.071 0.000
H65-H75 Diseases of middle ear and mastoid
0.929 0.071 0.000
C67.9 Bladder, unspecified
0.926 0.074 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.926 0.074 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.922 0.078 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.915 0.085 0.000
Chapter XXII Codes for special purposes
0.908 0.092 0.000
H91.9 Hearing loss, unspecified
0.903 0.097 0.000
C79 Secondary malignant neoplasm of other sites
0.903 0.097 0.000
C16 Malignant neoplasm of stomach
0.902 0.098 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.901 0.099 0.000
C67.6 Ureteric orifice
0.900 0.100 0.000
C18.9 Colon, unspecified
0.899 0.101 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.897 0.103 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.892 0.108 0.000
D73 Diseases of spleen
0.891 0.109 0.000
C77.9 Lymph node, unspecified
0.891 0.109 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.889 0.111 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.887 0.113 0.000
H90 Conductive and sensorineural hearing loss
0.884 0.116 0.000
T86 Failure and rejection of transplanted organs and tissues
0.878 0.122 0.000
C18.3 Hepatic flexure
0.873 0.127 0.000
C18.5 Splenic flexure
0.872 0.128 0.000
D55-D59 Haemolytic anaemias
0.868 0.132 0.000
C91 Lymphoid leukaemia
0.865 0.135 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.859 0.141 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.859 0.141 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.857 0.143 0.000
Y43.0 Antiallergic and antiemetic drugs
0.856 0.144 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.854 0.146 0.000
C83.3 Large cell (diffuse)
0.854 0.146 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.850 0.150 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.848 0.152 0.000
W22 Striking against or struck by other objects
0.847 0.153 0.000
T85.2 Mechanical complication of intraocular lens
0.846 0.154 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.846 0.154 0.000
C81 Hodgkin's disease
0.843 0.157 0.000
D68 Other coagulation defects
0.841 0.159 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.840 0.160 0.000
B02 Zoster [herpes zoster]
0.833 0.167 0.000
C18.6 Descending colon
0.832 0.168 0.000
B07 Viral warts
0.832 0.168 0.000
X60-X84 Intentional self-harm
0.832 0.168 0.000
C60-C63 Malignant neoplasms of male genital organs
0.827 0.173 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.825 0.174 0.000
B25-B34 Other viral diseases
0.824 0.176 0.000
B95-B98 Bacterial, viral and other infectious agents
0.822 0.178 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.821 0.179 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.821 0.179 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.819 0.181 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.815 0.185 0.000
C77.2 Intra-abdominal lymph nodes
0.815 0.185 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.813 0.187 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.812 0.188 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.811 0.189 0.000
Y60.0 During surgical operation
0.811 0.189 0.000
T00-T07 Injuries involving multiple body regions
0.809 0.191 0.000
C90.0 Multiple myeloma
0.809 0.191 0.000
H74 Other disorders of middle ear and mastoid
0.808 0.192 0.000
V40-V49 Car occupant injured in transport accident
0.806 0.194 0.000
C67.5 Bladder neck
0.806 0.194 0.000
C18.0 Caecum
0.803 0.197 0.000
Y44 Agents primarily affecting blood constituents
0.803 0.197 0.000
H93 Other disorders of ear, not elsewhere classified
0.801 0.199 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.801 0.199 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.800 0.200 0.000
D80-D89 Certain disorders involving the immune mechanism
0.799 0.201 0.000
W44 Foreign body entering into or through eye or natural orifice
0.795 0.205 0.000
C77.3 Axillary and upper limb lymph nodes
0.795 0.205 0.000
H90.2 Conductive hearing loss, unspecified
0.794 0.206 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.793 0.207 0.000
C67.2 Lateral wall of bladder
0.789 0.211 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.787 0.213 0.000
C17 Malignant neoplasm of small intestine
0.786 0.214 0.000
C21 Malignant neoplasm of anus and anal canal
0.786 0.214 0.000
D75 Other diseases of blood and blood-forming organs
0.785 0.215 0.000
C62 Malignant neoplasm of testis
0.782 0.218 0.000
C77.5 Intrapelvic lymph nodes
0.781 0.219 0.000
B35-B49 Mycoses
0.779 0.221 0.000
S10-S19 Injuries to the neck
0.779 0.221 0.000
B00 Herpesviral [herpes simplex] infections
0.778 0.222 0.000
C67.4 Posterior wall of bladder
0.778 0.222 0.000
C16.9 Stomach, unspecified
0.777 0.223 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.776 0.224 0.000
T25 Burn and corrosion of ankle and foot
0.775 0.225 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.774 0.226 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.773 0.227 0.000
D50-D53 Nutritional anaemias
0.772 0.228 0.000
W22.9 Unspecified place
0.771 0.229 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.765 0.235 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.764 0.236 0.000
D69 Purpura and other haemorrhagic conditions
0.763 0.237 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.762 0.238 0.000
D72 Other disorders of white blood cells
0.761 0.239 0.000
A80-A89 Viral infections of the central nervous system
0.760 0.240 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.760 0.240 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.759 0.240 0.000
Y00-Y09 Assault
0.757 0.243 0.000
X20-X29 Contact with venomous animals and plants
0.755 0.245 0.000
W75-W84 Other accidental threats to breathing
0.754 0.245 0.000
C77.4 Inguinal and lower limb lymph nodes
0.754 0.246 0.000
H65 Nonsuppurative otitis media
0.753 0.247 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.752 0.247 0.000
C95 Leukaemia of unspecified cell type
0.752 0.248 0.000
C16.6 Greater curvature of stomach, unspecified
0.752 0.248 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.752 0.248 0.000
X10-X19 Contact with heat and hot substances
0.751 0.249 0.000
H71 Cholesteatoma of middle ear
0.751 0.249 0.000
T81 Complications of procedures, not elsewhere classified
0.750 0.250 0.000
H90.0 Conductive hearing loss, bilateral
0.749 0.251 0.000
U80 Agent resistant to penicillin and related antibiotics
0.749 0.251 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.749 0.251 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.748 0.252 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.746 0.254 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.746 0.254 0.000
C67.1 Dome of bladder
0.745 0.255 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.744 0.255 0.000
C92 Myeloid leukaemia
0.743 0.257 0.000
C81.9 Hodgkin's disease, unspecified
0.743 0.257 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.743 0.257 0.000
C67.0 Trigone of bladder
0.740 0.259 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.738 0.262 0.000
D73.0 Hyposplenism
0.736 0.264 0.000
H66 Suppurative and unspecified otitis media
0.736 0.264 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.735 0.265 0.000
C66 Malignant neoplasm of ureter
0.733 0.266 0.000
B50-B64 Protozoal diseases
0.733 0.267 0.000
C18.1 Appendix
0.732 0.268 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.731 0.269 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.731 0.269 0.000
D59 Acquired haemolytic anaemia
0.730 0.269 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.728 0.272 0.000
H72 Perforation of tympanic membrane
0.726 0.274 0.000
C62.9 Testis, unspecified
0.726 0.274 0.000
C65 Malignant neoplasm of renal pelvis
0.725 0.275 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.724 0.276 0.000
V20-V29 Motorcycle rider injured in transport accident
0.724 0.276 0.000
C23 Malignant neoplasm of gallbladder
0.722 0.277 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.721 0.279 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.721 0.279 0.000
T21 Burn and corrosion of trunk
0.721 0.279 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.721 0.279 0.000
Y65 Other misadventures during surgical and medical care
0.720 0.279 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.720 0.280 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.720 0.280 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.718 0.282 0.000
C91.4 Hairy-cell leukaemia
0.718 0.282 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.716 0.284 0.000
D74 Methaemoglobinaemia
0.716 0.284 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.716 0.284 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.716 0.284 0.000
D73.8 Other diseases of spleen
0.716 0.284 0.000
C22.1 Intrahepatic bile duct carcinoma
0.716 0.284 0.000
C18.8 Overlapping lesion of colon
0.716 0.284 0.000
U80.1 Methicillin resistant agent
0.715 0.285 0.000
T33-T35 Frostbite
0.714 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.714 0.286 0.000
Y10-Y34 Event of undetermined intent
0.714 0.286 0.000
X85-X99 Assault
0.714 0.286 0.000
X30-X39 Exposure to forces of nature
0.714 0.286 0.000
X00-X09 Exposure to smoke, fire and flames
0.714 0.286 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.714 0.286 0.000
W65-W74 Accidental drowning and submersion
0.714 0.286 0.000
V98-V99 Other and unspecified transport accidents
0.714 0.286 0.000
V95-V97 Air and space transport accidents
0.714 0.286 0.000
V90-V94 Water transport accidents
0.714 0.286 0.000
V70-V79 Bus occupant injured in transport accident
0.714 0.286 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.714 0.286 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.714 0.286 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.714 0.286 0.000
V01-V09 Pedestrian injured in transport accident
0.714 0.286 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.711 0.289 0.000
C94 Other leukaemias of specified cell type
0.711 0.289 0.000
C93 Monocytic leukaemia
0.711 0.289 0.000
C88 Malignant immunoproliferative diseases
0.711 0.289 0.000
C86 Other specified types of T/NK-cell lymphoma
0.711 0.289 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.711 0.289 0.000
Y57 Other and unspecified drugs and medicaments
0.710 0.290 0.000
D73.5 Infarction of spleen
0.710 0.290 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.709 0.291 0.000
B99-B99 Other infectious diseases
0.709 0.291 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.708 0.292 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.708 0.292 0.000
B65-B83 Helminthiases
0.708 0.292 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.708 0.292 0.000
A75-A79 Rickettsioses
0.708 0.292 0.000
A70-A74 Other diseases caused by chlamydiae
0.708 0.292 0.000
A65-A69 Other spirochaetal diseases
0.708 0.292 0.000
A20-A28 Certain zoonotic bacterial diseases
0.708 0.292 0.000
A15-A19 Tuberculosis
0.708 0.292 0.000
B02.2 Zoster with other nervous system involvement
0.707 0.293 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.706 0.294 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.706 0.294 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.705 0.295 0.000
C18.2 Ascending colon
0.705 0.295 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.704 0.295 0.000
C15 Malignant neoplasm of oesophagus
0.704 0.296 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.704 0.296 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.703 0.297 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.703 0.297 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.703 0.297 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.703 0.297 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.703 0.297 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.702 0.297 0.000
B34 Viral infection of unspecified site
0.702 0.298 0.000
T36 Poisoning by systemic antibiotics
0.702 0.298 0.000
T92 Sequelae of injuries of upper limb
0.702 0.298 0.000
C67.8 Overlapping lesion of bladder
0.701 0.298 0.000
C67.7 Urachus
0.701 0.298 0.000
C91.0 Acute lymphoblastic leukaemia
0.701 0.299 0.000
C22.0 Liver cell carcinoma
0.701 0.299 0.000
D58 Other hereditary haemolytic anaemias
0.699 0.301 0.000
Q50-Q56 Congenital malformations of genital organs
0.699 0.301 0.000
T81.9 Unspecified complication of procedure
0.698 0.302 0.000
S90-S99 Injuries to the ankle and foot
0.698 0.302 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.697 0.302 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.697 0.302 0.000
T86.4 Liver transplant failure and rejection
0.697 0.303 0.000
W44.0 Home
0.696 0.304 0.000
Y59 Other and unspecified vaccines and biological substances
0.693 0.307 0.000
Y58 Bacterial vaccines
0.693 0.307 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.693 0.307 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.693 0.307 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.693 0.307 0.000
D68.9 Coagulation defect, unspecified
0.692 0.308 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.691 0.309 0.000
B02.9 Zoster without complication
0.690 0.310 0.000
T86.0 Bone-marrow transplant rejection
0.689 0.311 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.688 0.312 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.688 0.312 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.687 0.313 0.000
W29 Contact with other powered hand tools and household machinery
0.685 0.315 0.000
B15-B19 Viral hepatitis
0.685 0.315 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.684 0.316 0.000
D00-D09 In situ neoplasms
0.684 0.316 0.000
Y43.9 Primarily systemic agent, unspecified
0.683 0.317 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.683 0.317 0.000
Y43.6 Enzymes, not elsewhere classified
0.683 0.317 0.000
Y43.5 Acidifying and alkalising agents
0.683 0.317 0.000
Y43.2 Antineoplastic natural products
0.683 0.317 0.000
S31 Open wound of abdomen, lower back and pelvis
0.681 0.319 0.000
B06 Rubella [German measles]
0.679 0.320 0.000
B05 Measles
0.679 0.320 0.000
B01 Varicella [chickenpox]
0.679 0.320 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.679 0.320 0.000
B04 Monkeypox
0.679 0.320 0.000
B03 Smallpox
0.679 0.320 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.679 0.321 0.000
X50-X57 Overexertion, travel and privation
0.679 0.321 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.678 0.322 0.000
Q00-Q07 Congenital malformations of the nervous system
0.678 0.322 0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection
0.676 0.323 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.676 0.324 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.676 0.324 0.000
T02 Fractures involving multiple body regions
0.675 0.325 0.000
C90.2 Plasmacytoma, extramedullary
0.675 0.325 0.000
C16.3 Pyloric antrum
0.675 0.325 0.000
C16.5 Lesser curvature of stomach, unspecified
0.674 0.325 0.000
T20 Burn and corrosion of head and neck
0.674 0.326 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.673 0.327 0.000
W50-W64 Exposure to animate mechanical forces
0.673 0.327 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.672 0.328 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.672 0.328 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.672 0.328 0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.672 0.328 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.672 0.328 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.672 0.328 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.672 0.328 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.672 0.328 0.000
T44.0 Anticholinesterase agents
0.672 0.328 0.000
W20 Struck by thrown, projected or falling object
0.671 0.329 0.000
Y48 Anaesthetics and therapeutic gases
0.671 0.329 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.670 0.330 0.000
W46 Contact with hypodermic needle
0.669 0.330 0.000
W45 Foreign body or object entering through skin
0.669 0.330 0.000
W43 Exposure to vibration
0.669 0.330 0.000
W42 Exposure to noise
0.669 0.330 0.000
W41 Exposure to high-pressure jet
0.669 0.330 0.000
W40 Explosion of other materials
0.669 0.330 0.000
W39 Discharge of firework
0.669 0.330 0.000
W38 Explosion and rupture of other specified pressurised devices
0.669 0.330 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.669 0.330 0.000
W36 Explosion and rupture of gas cylinder
0.669 0.330 0.000
W35 Explosion and rupture of boiler
0.669 0.330 0.000
W34 Discharge from other and unspecified firearms
0.669 0.330 0.000
W33 Rifle, shotgun and larger firearm discharge
0.669 0.330 0.000
W32 Handgun discharge
0.669 0.330 0.000
W31 Contact with other and unspecified machinery
0.669 0.330 0.000
W30 Contact with agricultural machinery
0.669 0.330 0.000
W28 Contact with powered lawn mower
0.669 0.330 0.000
W27 Contact with nonpowered hand tool
0.669 0.330 0.000
W26 Contact with knife, sword or dagger
0.669 0.330 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.669 0.330 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.669 0.330 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.669 0.331 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.669 0.331 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.668 0.331 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.668 0.332 0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand
0.667 0.333 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.667 0.333 0.000
H91.3 Deaf mutism, not elsewhere classified
0.666 0.334 0.000
H91.2 Sudden idiopathic hearing loss
0.666 0.334 0.000
H91.1 Presbycusis
0.666 0.334 0.000
H91.0 Ototoxic hearing loss
0.666 0.334 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.666 0.334 0.000
H68 Eustachian salpingitis and obstruction
0.666 0.334 0.000
H67 Otitis media in diseases classified elsewhere
0.666 0.334 0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand
0.666 0.334 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.665 0.335 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.664 0.336 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.664 0.336 0.000
Y54.3 Benzothiadiazine derivatives
0.664 0.336 0.000
D67 Hereditary factor IX deficiency
0.664 0.336 0.000
D66 Hereditary factor VIII deficiency
0.664 0.336 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.664 0.336 0.000
C83.0 Small cell (diffuse)
0.662 0.337 0.000
T25.2 Burn of second degree of ankle and foot
0.662 0.338 0.000
Y64 Contaminated medical or biological substances
0.661 0.339 0.000
Y63 Failure in dosage during surgical and medical care
0.661 0.339 0.000
Y62 Failure of sterile precautions during surgical and medical care
0.661 0.339 0.000
Y61 Foreign object accidentally left in body during surgical and medical care
0.661 0.339 0.000
Y69 Unspecified misadventure during surgical and medical care
0.661 0.339 0.000
Y66 Nonadministration of surgical and medical care
0.661 0.339 0.000
H69 Other disorders of Eustachian tube
0.661 0.339 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.660 0.340 0.000
C21.0 Anus, unspecified
0.660 0.340 0.000
T82.1 Mechanical complication of cardiac electronic device
0.659 0.341 0.000
C91.9 Lymphoid leukaemia, unspecified
0.659 0.341 0.000
C62.1 Descended testis
0.658 0.342 0.000
Y49.2 Other and unspecified antidepressants
0.658 0.342 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.657 0.343 0.000
S60-S69 Injuries to the wrist and hand
0.657 0.343 0.000
C83.7 Burkitt's tumour
0.656 0.344 0.000
C83.6 Undifferentiated (diffuse)
0.656 0.344 0.000
C83.5 Lymphoblastic (diffuse)
0.656 0.344 0.000
C83.4 Immunoblastic (diffuse)
0.656 0.344 0.000
C83.2 Mixed small and large cell (diffuse)
0.656 0.344 0.000
C83.1 Small cleaved cell (diffuse)
0.656 0.344 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.655 0.345 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.654 0.346 0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.654 0.346 0.000
T92.1 Sequelae of fracture of arm
0.654 0.346 0.000
D68.8 Other specified coagulation defects
0.654 0.346 0.000
A00-A09 Intestinal infectious diseases
0.654 0.346 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.653 0.347 0.000
C84.5 Other and unspecified T-cell lymphomas
0.653 0.347 0.000
W22.2 School, other institution and public administrative area
0.653 0.347 0.000
V48 Car occupant injured in noncollision transport accident
0.653 0.347 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.652 0.348 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.652 0.348 0.000
B49 Unspecified mycosis
0.652 0.348 0.000
S30.1 Contusion of abdominal wall
0.651 0.349 0.000
S37 Injury of urinary and pelvic organs
0.651 0.349 0.000
H74.0 Tympanosclerosis
0.650 0.350 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.650 0.350 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.649 0.351 0.000
C67.3 Anterior wall of bladder
0.648 0.351 0.000
Y44.5 Thrombolytic drugs
0.648 0.352 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.648 0.352 0.000
C25 Malignant neoplasm of pancreas
0.647 0.353 0.000
D72.1 Eosinophilia
0.647 0.353 0.000
C16.8 Overlapping lesion of stomach
0.646 0.353 0.000
C16.4 Pylorus
0.646 0.353 0.000
C16.2 Body of stomach
0.646 0.353 0.000
C16.1 Fundus of stomach
0.646 0.353 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.645 0.355 0.000
T87 Complications peculiar to reattachment and amputation
0.645 0.355 0.000
Q80-Q89 Other congenital malformations
0.645 0.355 0.000
Y73 Gastro-enterology and urology devices associated with adverse incidents
0.644 0.356 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.643 0.357 0.000
Q35-Q37 Cleft lip and cleft palate
0.643 0.357 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.643 0.357 0.000
C84.0 Mycosis fungoides
0.643 0.357 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.643 0.357 0.000
H93.1 Tinnitus
0.642 0.358 0.000
Y54.5 Other diuretics
0.641 0.359 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.640 0.360 0.000
C90.3 Solitary plasmacytoma
0.640 0.360 0.000
C90.1 Plasma cell leukaemia
0.640 0.360 0.000
D86 Sarcoidosis
0.640 0.360 0.000
D68.6 Other Thrombophilia
0.639 0.361 0.000
D73.9 Disease of spleen, unspecified
0.639 0.361 0.000
D73.4 Cyst of spleen
0.639 0.361 0.000
D73.3 Abscess of spleen
0.639 0.361 0.000
D73.2 Chronic congestive splenomegaly
0.639 0.361 0.000
D73.1 Hypersplenism
0.639 0.361 0.000
T23 Burn and corrosion of wrist and hand
0.639 0.361 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.638 0.361 0.000
S20-S29 Injuries to the thorax
0.638 0.362 0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection
0.637 0.362 0.000
T80.6 Other serum reactions
0.637 0.362 0.000
T80.5 Anaphylactic shock due to serum
0.637 0.362 0.000
T80.4 Rh incompatibility reaction
0.637 0.362 0.000
T80.3 ABO incompatibility reaction
0.637 0.362 0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection
0.637 0.362 0.000
B35 Dermatophytosis
0.637 0.363 0.000
V80-V89 Other land transport accidents
0.636 0.363 0.000
H92 Otalgia and effusion of ear
0.636 0.364 0.000
B27 Infectious mononucleosis
0.636 0.364 0.000
T50.8 Diagnostic agents
0.636 0.364 0.000
T50.7 Analeptics and opioid receptor antagonists
0.636 0.364 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.636 0.364 0.000
T50.5 Appetite depressants
0.636 0.364 0.000
T50.4 Drugs affecting uric acid metabolism
0.636 0.364 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.636 0.364 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.636 0.364 0.000
T50.1 Loop [high-ceiling] diuretics
0.636 0.364 0.000
T50.0 Mineralocorticoids and their antagonists
0.636 0.364 0.000
Q60-Q64 Congenital malformations of the urinary system
0.635 0.365 0.000
A86 Unspecified viral encephalitis
0.635 0.365 0.000
W21 Striking against or struck by sports equipment
0.634 0.366 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.634 0.366 0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
0.634 0.366 0.000
H70 Mastoiditis and related conditions
0.632 0.367 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.632 0.368 0.000
D37.4 Colon
0.632 0.368 0.000
Y44.2 Anticoagulants
0.631 0.369 0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue
0.630 0.370 0.000
T86.3 Heart-lung transplant failure and rejection
0.630 0.370 0.000
T86.2 Heart transplant failure and rejection
0.630 0.370 0.000
D68.0 Von Willebrand's disease
0.628 0.372 0.000
Q43 Other congenital malformations of intestine
0.628 0.372 0.000
H74.2 Discontinuity and dislocation of ear ossicles
0.628 0.372 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.628 0.372 0.000
H93.8 Other specified disorders of ear
0.627 0.373 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.627 0.373 0.000
T82.3 Mechanical complication of other vascular grafts
0.627 0.373 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.626 0.374 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.625 0.375 0.000
S36 Injury of intra-abdominal organs
0.625 0.375 0.000
D06 Carcinoma in situ of cervix uteri
0.624 0.376 0.000
C92.0 Acute myeloid leukaemia
0.623 0.377 0.000
D51 Vitamin B12 deficiency anaemia
0.623 0.377 0.000
D57 Sickle-cell disorders
0.622 0.378 0.000
D56 Thalassaemia
0.622 0.378 0.000
D55 Anaemia due to enzyme disorders
0.622 0.378 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.622 0.378 0.000
S10 Superficial injury of neck
0.621 0.379 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.620 0.380 0.000
C91.7 Other lymphoid leukaemia
0.620 0.380 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.620 0.380 0.000
C91.5 Adult T-cell leukaemia
0.620 0.380 0.000
C91.3 Prolymphocytic leukaemia
0.620 0.380 0.000
C91.2 Subacute lymphocytic leukaemia
0.620 0.380 0.000
H65.4 Other chronic nonsuppurative otitis media
0.620 0.380 0.000
W25 Contact with sharp glass
0.619 0.381 0.000
D68.2 Hereditary deficiency of other clotting factors
0.619 0.381 0.000
B00.9 Herpesviral infection, unspecified
0.619 0.381 0.000
D83 Common variable immunodeficiency
0.618 0.381 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.618 0.382 0.000
D84 Other immunodeficiencies
0.618 0.382 0.000
C17.2 Ileum
0.617 0.383 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.616 0.384 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.616 0.384 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.616 0.384 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.616 0.384 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.616 0.384 0.000
S30.2 Contusion of external genital organs
0.616 0.384 0.000
C22.7 Other specified carcinomas of liver
0.616 0.384 0.000
C22.4 Other sarcomas of liver
0.616 0.384 0.000
C22.3 Angiosarcoma of liver
0.616 0.384 0.000
C22.2 Hepatoblastoma
0.616 0.384 0.000
C51-C58 Malignant neoplasms of female genital organs
0.615 0.385 0.000
H73 Other disorders of tympanic membrane
0.614 0.385 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.614 0.386 0.000
D75.1 Secondary polycythaemia
0.613 0.387 0.000
Y60.9 During unspecified surgical and medical care
0.613 0.387 0.000
Y60.8 During other surgical and medical care
0.613 0.387 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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