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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs78765259
log Bayes Factor = 18.3432
Chromosome 18   position 42,749,311  (GRCh37) Explore rs78765259 on Ensembl!
Variant rs78765259 is part of Cluster X0256

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E65-E68 Obesity and other hyperalimentation
0.999 0.001 0.000
E66 Obesity
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
E66.9 Obesity, unspecified
0.996 0.004 0.000
Chapter I Certain infectious and parasitic diseases
0.995 0.005 0.000
K40-K46 Hernia
0.995 0.005 0.000
S00-S09 Injuries to the head
0.992 0.008 0.000
J40-J47 Chronic lower respiratory diseases
0.991 0.009 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.990 0.010 0.000
Chapter VII Diseases of the eye and adnexa
0.987 0.013 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.985 0.015 0.000
J45 Asthma
0.983 0.017 0.000
Chapter V Mental and behavioural disorders
0.982 0.018 0.000
H30-H36 Disorders of choroid and retina
0.982 0.018 0.000
J45.9 Asthma, unspecified
0.980 0.020 0.000
E66.8 Other obesity
0.978 0.022 0.000
H35 Other retinal disorders
0.978 0.022 0.000
E10-E14 Diabetes mellitus
0.978 0.022 0.000
K43 Ventral hernia
0.978 0.022 0.000
I71 Aortic aneurysm and dissection
0.977 0.023 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.974 0.026 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.970 0.030 0.000
K90-K93 Other diseases of the digestive system
0.970 0.030 0.000
H35.3 Degeneration of macula and posterior pole
0.962 0.038 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.961 0.039 0.000
K92 Other diseases of digestive system
0.958 0.042 0.000
L40-L45 Papulosquamous disorders
0.950 0.050 0.000
S01 Open wound of head
0.948 0.052 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.948 0.052 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.944 0.056 0.000
Chapter XX External causes of morbidity and mortality
0.944 0.056 0.000
B95-B98 Bacterial, viral and other infectious agents
0.937 0.063 0.000
J44 Other chronic obstructive pulmonary disease
0.936 0.064 0.000
Chapter II Neoplasms
0.933 0.067 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.927 0.073 0.000
K42 Umbilical hernia
0.923 0.077 0.000
C15-C26 Malignant neoplasms of digestive organs
0.921 0.079 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.921 0.079 0.000
K50-K52 Noninfective enteritis and colitis
0.920 0.080 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.919 0.081 0.000
M05-M14 Inflammatory polyarthropathies
0.912 0.088 0.000
L03 Cellulitis
0.911 0.089 0.000
S40-S49 Injuries to the shoulder and upper arm
0.910 0.090 0.000
M06 Other rheumatoid arthritis
0.908 0.092 0.000
B25-B34 Other viral diseases
0.907 0.093 0.000
L40 Psoriasis
0.907 0.093 0.000
F10.1 Harmful use
0.903 0.097 0.000
E11 Non-insulin-dependent diabetes mellitus
0.901 0.099 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.900 0.100 0.000
M06.9 Rheumatoid arthritis, unspecified
0.897 0.103 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.896 0.104 0.000
D50-D53 Nutritional anaemias
0.896 0.104 0.000
F10.2 Dependence syndrome
0.895 0.105 0.000
F10.0 Acute intoxication
0.895 0.105 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.892 0.108 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.888 0.112 0.000
S50-S59 Injuries to the elbow and forearm
0.888 0.112 0.000
I80 Phlebitis and thrombophlebitis
0.883 0.117 0.000
H35.8 Other specified retinal disorders
0.882 0.118 0.000
K50 Crohn's disease [regional enteritis]
0.882 0.118 0.000
I30-I52 Other forms of heart disease
0.878 0.122 0.000
J90-J94 Other diseases of pleura
0.878 0.122 0.000
K46 Unspecified abdominal hernia
0.872 0.128 0.000
S01.0 Open wound of scalp
0.871 0.129 0.000
J20-J22 Other acute lower respiratory infections
0.870 0.130 0.000
I05-I09 Chronic rheumatic heart diseases
0.868 0.132 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.866 0.134 0.000
J95-J99 Other diseases of the respiratory system
0.865 0.135 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.864 0.136 0.000
I78 Diseases of capillaries
0.862 0.137 0.000
E10 Insulin-dependent diabetes mellitus
0.862 0.138 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.862 0.138 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.860 0.140 0.000
D50 Iron deficiency anaemia
0.860 0.140 0.000
S20-S29 Injuries to the thorax
0.859 0.141 0.000
K65-K67 Diseases of peritoneum
0.857 0.143 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.856 0.144 0.000
L03.9 Cellulitis, unspecified
0.856 0.144 0.000
K50.9 Crohn's disease, unspecified
0.853 0.147 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.853 0.147 0.000
D00-D09 In situ neoplasms
0.852 0.148 0.000
S00 Superficial injury of head
0.850 0.150 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.849 0.151 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.848 0.152 0.000
C18 Malignant neoplasm of colon
0.846 0.154 0.000
B34 Viral infection of unspecified site
0.844 0.156 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.844 0.156 0.000
A30-A49 Other bacterial diseases
0.843 0.157 0.000
E14 Unspecified diabetes mellitus
0.842 0.158 0.000
S06 Intracranial injury
0.842 0.158 0.000
K70-K77 Diseases of liver
0.837 0.163 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.833 0.167 0.000
S01.9 Open wound of head, part unspecified
0.830 0.170 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.830 0.170 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.829 0.171 0.000
S70-S79 Injuries to the hip and thigh
0.827 0.173 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.826 0.174 0.000
L40.5 Arthropathic psoriasis
0.825 0.175 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.824 0.176 0.000
R47-R49 Symptoms and signs involving speech and voice
0.824 0.176 0.000
K92.1 Melaena
0.823 0.177 0.000
S09 Other and unspecified injuries of head
0.822 0.178 0.000
I84 Haemorrhoids
0.818 0.182 0.000
S40 Superficial injury of shoulder and upper arm
0.817 0.183 0.000
M06.0 Seronegative rheumatoid arthritis
0.817 0.183 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.816 0.184 0.000
I71.0 Dissection of aorta [any part]
0.807 0.193 0.000
E11.9 Without complications
0.806 0.194 0.000
D50.9 Iron deficiency anaemia, unspecified
0.806 0.194 0.000
K55-K64 Other diseases of intestines
0.805 0.195 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.803 0.197 0.000
C71 Malignant neoplasm of brain
0.803 0.197 0.000
R30-R39 Symptoms and signs involving the urinary system
0.802 0.198 0.000
F10.3 Withdrawal state
0.802 0.198 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.801 0.199 0.000
S52 Fracture of forearm
0.800 0.200 0.000
L43 Lichen planus
0.800 0.200 0.000
D05 Carcinoma in situ of breast
0.799 0.201 0.000
B34.9 Viral infection, unspecified
0.799 0.201 0.000
K92.9 Disease of digestive system, unspecified
0.798 0.202 0.000
K11 Diseases of salivary glands
0.793 0.207 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.792 0.208 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.789 0.211 0.000
L03.3 Cellulitis of trunk
0.787 0.213 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.787 0.213 0.000
H53-H54 Visual disturbances and blindness
0.787 0.213 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.787 0.213 0.000
R35 Polyuria
0.787 0.213 0.000
E10.9 Without complications
0.786 0.214 0.000
K66 Other disorders of peritoneum
0.785 0.215 0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.784 0.216 0.000
H31 Other disorders of choroid
0.783 0.217 0.000
B35-B49 Mycoses
0.781 0.219 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.780 0.220 0.000
R49 Voice disturbances
0.780 0.220 0.000
F11 Mental and behavioural disorders due to use of opioids
0.779 0.221 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.779 0.221 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.778 0.222 0.000
L08 Other local infections of skin and subcutaneous tissue
0.778 0.222 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.777 0.223 0.000
I38 Endocarditis, valve unspecified
0.777 0.223 0.000
I77 Other disorders of arteries and arterioles
0.776 0.224 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.776 0.224 0.000
B65-B83 Helminthiases
0.775 0.224 0.000
K70 Alcoholic liver disease
0.775 0.225 0.000
S02 Fracture of skull and facial bones
0.774 0.226 0.000
S42 Fracture of shoulder and upper arm
0.774 0.226 0.000
E40-E46 Malnutrition
0.774 0.226 0.000
I50 Heart failure
0.774 0.226 0.000
J98 Other respiratory disorders
0.774 0.226 0.000
I84.4 External haemorrhoids with other complications
0.772 0.228 0.000
I78.1 Naevus, nonneoplastic
0.771 0.229 0.000
H35.4 Peripheral retinal degeneration
0.771 0.229 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.770 0.230 0.000
J22 Unspecified acute lower respiratory infection
0.768 0.232 0.000
C20 Malignant neoplasm of rectum
0.767 0.233 0.000
I82 Other venous embolism and thrombosis
0.766 0.234 0.000
I72 Other aneurysm
0.763 0.236 0.000
H35.7 Separation of retinal layers
0.763 0.237 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.763 0.237 0.000
C21 Malignant neoplasm of anus and anal canal
0.763 0.237 0.000
S40.0 Contusion of shoulder and upper arm
0.761 0.239 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.760 0.240 0.000
J92 Pleural plaque
0.760 0.240 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.759 0.241 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.757 0.243 0.000
W00-W19 Falls
0.757 0.243 0.000
J94 Other pleural conditions
0.754 0.246 0.000
S60-S69 Injuries to the wrist and hand
0.753 0.247 0.000
M45-M49 Spondylopathies
0.752 0.248 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.752 0.248 0.000
L40.0 Psoriasis vulgaris
0.752 0.248 0.000
I31 Other diseases of pericardium
0.751 0.249 0.000
I84.5 External haemorrhoids without complication
0.751 0.249 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.751 0.249 0.000
K04 Diseases of pulp and periapical tissues
0.750 0.250 0.000
H43-H45 Disorders of vitreous body and globe
0.750 0.250 0.000
L03.8 Cellulitis of other sites
0.749 0.250 0.000
R49.0 Dysphonia
0.749 0.251 0.000
C18.7 Sigmoid colon
0.748 0.252 0.000
S32 Fracture of lumbar spine and pelvis
0.748 0.252 0.000
K51 Ulcerative colitis
0.748 0.252 0.000
K42.0 Umbilical hernia with obstruction, without gangrene
0.746 0.254 0.000
W50-W64 Exposure to animate mechanical forces
0.745 0.255 0.000
A80-A89 Viral infections of the central nervous system
0.744 0.256 0.000
L40.9 Psoriasis, unspecified
0.743 0.256 0.000
J60-J70 Lung diseases due to external agents
0.743 0.257 0.000
I81 Portal vein thrombosis
0.742 0.258 0.000
A41 Other septicaemia
0.742 0.258 0.000
E14.9 Without complications
0.741 0.259 0.000
D50.8 Other iron deficiency anaemias
0.741 0.259 0.000
K09 Cysts of oral region, not elsewhere classified
0.741 0.259 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.740 0.260 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.740 0.260 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.740 0.260 0.000
K13 Other diseases of lip and oral mucosa
0.740 0.260 0.000
Y00-Y09 Assault
0.739 0.260 0.000
J46 Status asthmaticus
0.737 0.263 0.000
I50.0 Congestive heart failure
0.737 0.263 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.736 0.264 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.735 0.265 0.000
K60 Fissure and fistula of anal and rectal regions
0.735 0.265 0.000
M05 Seropositive rheumatoid arthritis
0.732 0.267 0.000
K11.5 Sialolithiasis
0.732 0.268 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.731 0.269 0.000
B15-B19 Viral hepatitis
0.730 0.269 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.729 0.271 0.000
K92.0 Haematemesis
0.728 0.272 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.728 0.272 0.000
S01.4 Open wound of cheek and temporomandibular area
0.727 0.273 0.000
S90-S99 Injuries to the ankle and foot
0.726 0.274 0.000
M14 Arthropathies in other diseases classified elsewhere
0.726 0.274 0.000
A00-A09 Intestinal infectious diseases
0.726 0.274 0.000
F20 Schizophrenia
0.726 0.274 0.000
Y40 Systemic antibiotics
0.725 0.275 0.000
J00-J06 Acute upper respiratory infections
0.724 0.276 0.000
S80-S89 Injuries to the knee and lower leg
0.724 0.276 0.000
S01.1 Open wound of eyelid and periocular area
0.724 0.276 0.000
S01.7 Multiple open wounds of head
0.723 0.276 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.723 0.277 0.000
F60-F69 Disorders of adult personality and behaviour
0.722 0.278 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.722 0.278 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.722 0.278 0.000
V10-V19 Pedal cyclist injured in transport accident
0.722 0.278 0.000
H52 Disorders of refraction and accommodation
0.722 0.278 0.000
H35.0 Background retinopathy and retinal vascular changes
0.720 0.279 0.000
I46 Cardiac arrest
0.720 0.280 0.000
K41 Femoral hernia
0.719 0.281 0.000
F99-F99 Unspecified mental disorder
0.719 0.281 0.000
H34 Retinal vascular occlusions
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.717 0.283 0.000
E67 Other hyperalimentation
0.716 0.283 0.000
E68 Sequelae of hyperalimentation
0.716 0.283 0.000
E65 Localised adiposity
0.716 0.283 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.716 0.284 0.000
E66.1 Drug-induced obesity
0.716 0.284 0.000
E66.0 Obesity due to excess calories
0.716 0.284 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.716 0.284 0.000
I95 Hypotension
0.716 0.284 0.000
H35.6 Retinal haemorrhage
0.715 0.285 0.000
E11.6 With other specified complications
0.715 0.285 0.000
B99-B99 Other infectious diseases
0.714 0.286 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.714 0.286 0.000
B50-B64 Protozoal diseases
0.714 0.286 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.714 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.714 0.286 0.000
A75-A79 Rickettsioses
0.714 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.714 0.286 0.000
A65-A69 Other spirochaetal diseases
0.714 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.714 0.286 0.000
A15-A19 Tuberculosis
0.714 0.286 0.000
T79-T79 Certain early complications of trauma
0.713 0.287 0.000
K45 Other abdominal hernia
0.713 0.287 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.712 0.288 0.000
S08 Traumatic amputation of part of head
0.711 0.289 0.000
S07 Crushing injury of head
0.711 0.289 0.000
S05 Injury of eye and orbit
0.711 0.289 0.000
S04 Injury of cranial nerves
0.711 0.289 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.711 0.289 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.711 0.289 0.000
J41 Simple and mucopurulent chronic bronchitis
0.710 0.290 0.000
M80-M85 Disorders of bone density and structure
0.710 0.290 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.710 0.290 0.000
S01.8 Open wound of other parts of head
0.708 0.292 0.000
C71.1 Frontal lobe
0.708 0.292 0.000
L50-L54 Urticaria and erythema
0.707 0.293 0.000
L10-L14 Bullous disorders
0.706 0.294 0.000
J45.8 Mixed asthma
0.705 0.295 0.000
J45.1 Nonallergic asthma
0.705 0.295 0.000
I07 Rheumatic tricuspid valve diseases
0.705 0.295 0.000
M06.3 Rheumatoid nodule
0.704 0.296 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.704 0.296 0.000
F80-F89 Disorders of psychological development
0.704 0.296 0.000
F70-F79 Mental retardation
0.704 0.296 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.704 0.296 0.000
H30 Chorioretinal inflammation
0.704 0.296 0.000
S52.6 Fracture of lower end of both ulna and radius
0.703 0.297 0.000
D52 Folate deficiency anaemia
0.702 0.298 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.702 0.298 0.000
Chapter VI Diseases of the nervous system
0.702 0.298 0.000
H35.9 Retinal disorder, unspecified
0.701 0.299 0.000
H35.5 Hereditary retinal dystrophy
0.701 0.299 0.000
H35.2 Other proliferative retinopathy
0.701 0.299 0.000
H35.1 Retinopathy of prematurity
0.701 0.299 0.000
E12 Malnutrition-related diabetes mellitus
0.701 0.299 0.000
K43.7 Other and unspecified ventral hernia with gangrene
0.701 0.299 0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.701 0.299 0.000
K43.5 Parastomal hernia without obstruction or gangrene
0.701 0.299 0.000
K43.4 Parastomal hernia with gangrene
0.701 0.299 0.000
K43.3 Parastomal hernia with obstruction, without gangrene
0.701 0.299 0.000
K43.2 Incisional hernia without obstruction or gangrene
0.701 0.299 0.000
K43.1 Ventral hernia with gangrene
0.701 0.299 0.000
K66.0 Peritoneal adhesions
0.701 0.299 0.000
Chapter XXII Codes for special purposes
0.701 0.299 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.700 0.300 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.700 0.300 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.700 0.300 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.700 0.300 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.700 0.300 0.000
D55-D59 Haemolytic anaemias
0.700 0.300 0.000
S09.9 Unspecified injury of head
0.700 0.300 0.000
E20-E35 Disorders of other endocrine glands
0.699 0.301 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.699 0.301 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.698 0.301 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.698 0.301 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.698 0.301 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.698 0.301 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.698 0.301 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.698 0.301 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.698 0.301 0.000
E13 Other specified diabetes mellitus
0.698 0.302 0.000
I30 Acute pericarditis
0.697 0.303 0.000
K50.1 Crohn's disease of large intestine
0.697 0.303 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.696 0.304 0.000
S27 Injury of other and unspecified intrathoracic organs
0.696 0.304 0.000
F10.9 Unspecified mental and behavioural disorder
0.696 0.304 0.000
F10.8 Other mental and behavioural disorders
0.696 0.304 0.000
F10.7 Residual and late-onset psychotic disorder
0.696 0.304 0.000
F10.6 Amnesic syndrome
0.696 0.304 0.000
F10.5 Psychotic disorder
0.696 0.304 0.000
F10.4 Withdrawal state with delirium
0.696 0.304 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.695 0.304 0.000
C45 Mesothelioma
0.694 0.306 0.000
I08 Multiple valve diseases
0.693 0.307 0.000
L43.9 Lichen planus, unspecified
0.692 0.308 0.000
K61 Abscess of anal and rectal regions
0.691 0.309 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.691 0.309 0.000
L20-L30 Dermatitis and eczema
0.691 0.309 0.000
V80-V89 Other land transport accidents
0.690 0.310 0.000
D51 Vitamin B12 deficiency anaemia
0.690 0.310 0.000
S52.0 Fracture of upper end of ulna
0.689 0.311 0.000
K92.8 Other specified diseases of digestive system
0.687 0.313 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.685 0.314 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.684 0.316 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.684 0.316 0.000
T31 Burns classified according to extent of body surface involved
0.684 0.316 0.000
J42 Unspecified chronic bronchitis
0.683 0.317 0.000
E11.2 With renal complications
0.683 0.317 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.683 0.317 0.000
C73 Malignant neoplasm of thyroid gland
0.682 0.318 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.682 0.318 0.000
L44 Other papulosquamous disorders
0.681 0.318 0.000
L41 Parapsoriasis
0.681 0.318 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.681 0.318 0.000
L42 Pityriasis rosea
0.681 0.318 0.000
C16 Malignant neoplasm of stomach
0.681 0.319 0.000
J90 Pleural effusion, not elsewhere classified
0.681 0.319 0.000
K70.4 Alcoholic hepatic failure
0.680 0.320 0.000
H10-H13 Disorders of conjunctiva
0.680 0.320 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.680 0.320 0.000
L04 Acute lymphadenitis
0.680 0.320 0.000
L01 Impetigo
0.680 0.320 0.000
L00 Staphylococcal scalded skin syndrome
0.680 0.320 0.000
R33 Retention of urine
0.679 0.321 0.000
J98.4 Other disorders of lung
0.679 0.321 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.678 0.321 0.000
K40 Inguinal hernia
0.678 0.322 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.677 0.323 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.677 0.323 0.000
L03.0 Cellulitis of finger and toe
0.677 0.323 0.000
I88 Nonspecific lymphadenitis
0.677 0.323 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.677 0.323 0.000
Y35-Y36 Legal intervention and operations of war
0.677 0.323 0.000
Y10-Y34 Event of undetermined intent
0.677 0.323 0.000
X85-X99 Assault
0.677 0.323 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.677 0.323 0.000
X50-X57 Overexertion, travel and privation
0.677 0.323 0.000
X30-X39 Exposure to forces of nature
0.677 0.323 0.000
X20-X29 Contact with venomous animals and plants
0.677 0.323 0.000
X10-X19 Contact with heat and hot substances
0.677 0.323 0.000
X00-X09 Exposure to smoke, fire and flames
0.677 0.323 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.677 0.323 0.000
W75-W84 Other accidental threats to breathing
0.677 0.323 0.000
W65-W74 Accidental drowning and submersion
0.677 0.323 0.000
V98-V99 Other and unspecified transport accidents
0.677 0.323 0.000
V95-V97 Air and space transport accidents
0.677 0.323 0.000
V90-V94 Water transport accidents
0.677 0.323 0.000
V70-V79 Bus occupant injured in transport accident
0.677 0.323 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.677 0.323 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.677 0.323 0.000
V40-V49 Car occupant injured in transport accident
0.677 0.323 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.677 0.323 0.000
V01-V09 Pedestrian injured in transport accident
0.677 0.323 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.677 0.323 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.676 0.324 0.000
I70 Atherosclerosis
0.675 0.324 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.675 0.325 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.675 0.325 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.674 0.326 0.000
S01.2 Open wound of nose
0.673 0.327 0.000
R47 Speech disturbances, not elsewhere classified
0.672 0.328 0.000
I05 Rheumatic mitral valve diseases
0.671 0.329 0.000
S00.9 Superficial injury of head, part unspecified
0.670 0.330 0.000
C15 Malignant neoplasm of oesophagus
0.669 0.330 0.000
I85 Oesophageal varices
0.669 0.330 0.000
E11.4 With neurological complications
0.669 0.331 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.669 0.331 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.669 0.331 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.669 0.331 0.000
M91-M94 Chondropathies
0.668 0.332 0.000
J92.9 Pleural plaque without asbestos
0.668 0.332 0.000
E11.3 With ophthalmic complications
0.668 0.332 0.000
H36 Retinal disorders in diseases classified elsewhere
0.667 0.333 0.000
H54 Blindness and low vision
0.667 0.333 0.000
C91 Lymphoid leukaemia
0.666 0.334 0.000
S72 Fracture of femur
0.666 0.334 0.000
L89 Decubitus ulcer
0.666 0.334 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.666 0.334 0.000
J94.8 Other specified pleural conditions
0.666 0.334 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.663 0.337 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.663 0.337 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.662 0.338 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.662 0.338 0.000
K42.1 Umbilical hernia with gangrene
0.662 0.338 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.661 0.339 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.661 0.339 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.661 0.339 0.000
C17 Malignant neoplasm of small intestine
0.661 0.339 0.000
C23 Malignant neoplasm of gallbladder
0.661 0.339 0.000
M11 Other crystal arthropathies
0.660 0.339 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.660 0.340 0.000
C71.2 Temporal lobe
0.659 0.341 0.000
M60-M63 Disorders of muscles
0.659 0.341 0.000
M00-M03 Infectious arthropathies
0.659 0.341 0.000
Y43 Primarily systemic agents
0.658 0.342 0.000
S20 Superficial injury of thorax
0.657 0.343 0.000
S51 Open wound of forearm
0.656 0.344 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.656 0.344 0.000
I87 Other disorders of veins
0.656 0.344 0.000
W20-W49 Exposure to inanimate mechanical forces
0.655 0.344 0.000
S06.0 Concussion
0.655 0.345 0.000
C18.9 Colon, unspecified
0.654 0.346 0.000
S06.5 Traumatic subdural haemorrhage
0.654 0.346 0.000
M12 Other specific arthropathies
0.654 0.346 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.654 0.346 0.000
M08 Juvenile arthritis
0.654 0.346 0.000
C69 Malignant neoplasm of eye and adnexa
0.653 0.347 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.653 0.347 0.000
S48 Traumatic amputation of shoulder and upper arm
0.653 0.347 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.653 0.347 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.653 0.347 0.000
S44 Injury of nerves at shoulder and upper arm level
0.653 0.347 0.000
S41 Open wound of shoulder and upper arm
0.653 0.347 0.000
S47 Crushing injury of shoulder and upper arm
0.653 0.347 0.000
S42.2 Fracture of upper end of humerus
0.653 0.347 0.000
C18.3 Hepatic flexure
0.652 0.348 0.000
M40-M43 Deforming dorsopathies
0.652 0.348 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.652 0.348 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.651 0.349 0.000
M06.8 Other specified rheumatoid arthritis
0.651 0.349 0.000
M06.4 Inflammatory polyarthropathy
0.651 0.349 0.000
M06.2 Rheumatoid bursitis
0.651 0.349 0.000
M06.1 Adult-onset Still's disease
0.651 0.349 0.000
J20 Acute bronchitis
0.651 0.349 0.000
B33 Other viral diseases, not elsewhere classified
0.650 0.349 0.000
B30 Viral conjunctivitis
0.650 0.349 0.000
B27 Infectious mononucleosis
0.650 0.349 0.000
B26 Mumps
0.650 0.349 0.000
B25 Cytomegaloviral disease
0.650 0.349 0.000
X60-X84 Intentional self-harm
0.650 0.350 0.000
L40.8 Other psoriasis
0.650 0.350 0.000
L40.4 Guttate psoriasis
0.650 0.350 0.000
L40.3 Pustulosis palmaris et plantaris
0.650 0.350 0.000
L40.2 Acrodermatitis continua
0.650 0.350 0.000
L40.1 Generalised pustular psoriasis
0.650 0.350 0.000
S00.1 Contusion of eyelid and periocular area
0.650 0.350 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.649 0.351 0.000
K60.3 Anal fistula
0.649 0.351 0.000
C21.0 Anus, unspecified
0.649 0.351 0.000
S71 Open wound of hip and thigh
0.648 0.351 0.000
K60.1 Chronic anal fissure
0.648 0.352 0.000
I34 Nonrheumatic mitral valve disorders
0.648 0.352 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.648 0.352 0.000
H55-H59 Other disorders of eye and adnexa
0.647 0.352 0.000
F20.9 Schizophrenia, unspecified
0.647 0.353 0.000
K66.8 Other specified disorders of peritoneum
0.647 0.353 0.000
E11.8 With unspecified complications
0.646 0.354 0.000
E11.7 With multiple complications
0.646 0.354 0.000
E11.1 With ketoacidosis
0.646 0.354 0.000
E11.0 With coma
0.646 0.354 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.646 0.354 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.646 0.354 0.000
K03 Other diseases of hard tissues of teeth
0.645 0.354 0.000
K00 Disorders of tooth development and eruption
0.645 0.354 0.000
M86-M90 Other osteopathies
0.645 0.355 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.645 0.355 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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