TreeWAS – Variant ID: rs78835444

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
M50-M54 Other dorsopathies	1.000	0.000
M54 Dorsalgia	1.000	0.000
Chapter VIII Diseases of the ear and mastoid process	0.999	0.001
M45-M49 Spondylopathies	0.998	0.002
M47 Spondylosis	0.993	0.007
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.993	0.007
M54.3 Sciatica	0.991	0.009
M54.5 Low back pain	0.983	0.017
H65-H75 Diseases of middle ear and mastoid	0.981	0.019
M54.39 Sciatica (Site unspecified)	0.979	0.021
M54.9 Dorsalgia, unspecified	0.972	0.028
H60-H62 Diseases of external ear	0.970	0.030
M54.59 Low back pain (Site unspecified)	0.968	0.032
H72 Perforation of tympanic membrane	0.968	0.032
M47.8 Other spondylosis	0.963	0.037
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.963	0.037
S80-S89 Injuries to the knee and lower leg	0.957	0.043
H72.9 Perforation of tympanic membrane, unspecified	0.956	0.044
H60 Otitis externa	0.956	0.044
T85 Complications of other internal prosthetic devices, implants and grafts	0.956	0.044
M54.99 Dorsalgia, unspecified (Site unspecified)	0.955	0.045
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.955	0.045
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.949	0.051
Chapter VII Diseases of the eye and adnexa	0.930	0.070
C18 Malignant neoplasm of colon	0.929	0.071
C15-C26 Malignant neoplasms of digestive organs	0.928	0.072
Chapter II Neoplasms	0.928	0.072
H90-H95 Other disorders of ear	0.923	0.077
H30-H36 Disorders of choroid and retina	0.922	0.078
M47.9 Spondylosis, unspecified	0.916	0.084
Chapter IV Endocrine, nutritional and metabolic diseases	0.916	0.084
S82 Fracture of lower leg, including ankle	0.915	0.085
M47.86 Other spondylosis (Lumbar region)	0.913	0.087
C18.9 Colon, unspecified	0.909	0.091
H33 Retinal detachments and breaks	0.907	0.093
T20-T25 Burns and corrosions of external body surface, specified by site	0.907	0.093
T66-T78 Other and unspecified effects of external causes	0.907	0.093
C18.0 Caecum	0.905	0.095
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.902	0.098
H90 Conductive and sensorineural hearing loss	0.898	0.102
H60.9 Otitis externa, unspecified	0.896	0.104
E20-E35 Disorders of other endocrine glands	0.893	0.107
S50-S59 Injuries to the elbow and forearm	0.890	0.110
T88 Other complications of surgical and medical care, not elsewhere classified	0.888	0.112
M47.2 Other spondylosis with radiculopathy	0.887	0.113
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.884	0.116
S10-S19 Injuries to the neck	0.881	0.119
M86-M90 Other osteopathies	0.879	0.121
M51 Other intervertebral disk disorders	0.876	0.124
M54.36 Sciatica (Lumbar region)	0.872	0.128
H35 Other retinal disorders	0.866	0.134
M46 Other inflammatory spondylopathies	0.865	0.135
D00-D09 In situ neoplasms	0.861	0.139
S82.2 Fracture of shaft of tibia	0.861	0.139
C20 Malignant neoplasm of rectum	0.860	0.140
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.859	0.141
T78 Adverse effects, not elsewhere classified	0.859	0.141
M47.99 Spondylosis, unspecified (Site unspecified)	0.859	0.141
H60.3 Other infective otitis externa	0.859	0.141
H33.0 Retinal detachment with retinal break	0.857	0.143
C18.6 Descending colon	0.857	0.143
H90.2 Conductive hearing loss, unspecified	0.855	0.145
H33.3 Retinal breaks without detachment	0.854	0.146
M47.87 Other spondylosis (Lumbosacral region)	0.849	0.151
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.848	0.152
S90-S99 Injuries to the ankle and foot	0.846	0.154
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.844	0.156
S30 Superficial injury of abdomen, lower back and pelvis	0.843	0.157
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.841	0.159
H66 Suppurative and unspecified otitis media	0.839	0.161
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.838	0.162
M70-M79 Other soft tissue disorders	0.836	0.164
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.835	0.165
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.834	0.166
Chapter XX External causes of morbidity and mortality	0.831	0.169
H18 Other disorders of cornea	0.828	0.172
T85.2 Mechanical complication of intraocular lens	0.828	0.172
Q38-Q45 Other congenital malformations of the digestive system	0.827	0.173
T88.4 Failed or difficult intubation	0.826	0.174
T79-T79 Certain early complications of trauma	0.823	0.177
S52 Fracture of forearm	0.820	0.180
M51.8 Other specified intervertebral disk disorders	0.819	0.181
M47.80 Other spondylosis (Multiple sites in spine)	0.817	0.183
S82.6 Fracture of lateral malleolus	0.815	0.185
S70-S79 Injuries to the hip and thigh	0.813	0.187
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.813	0.187
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.813	0.187
T80 Complications following infusion, transfusion and therapeutic injection	0.812	0.188
H35.8 Other specified retinal disorders	0.809	0.191
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.806	0.194
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)	0.805	0.195
S32 Fracture of lumbar spine and pelvis	0.803	0.197
M45 Ankylosing spondylitis	0.802	0.197
E10-E14 Diabetes mellitus	0.798	0.202
M47.84 Other spondylosis (Thoracic region)	0.796	0.204
H72.0 Central perforation of tympanic membrane	0.793	0.207
T87 Complications peculiar to reattachment and amputation	0.792	0.208
Q00-Q07 Congenital malformations of the nervous system	0.792	0.208
S81 Open wound of lower leg	0.790	0.210
Q20-Q28 Congenital malformations of the circulatory system	0.789	0.211
M40-M43 Deforming dorsopathies	0.789	0.211
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.788	0.212
M54.50 Low back pain (Multiple sites in spine)	0.787	0.213
H16 Keratitis	0.786	0.214
M79 Other soft tissue disorders, not elsewhere classified	0.785	0.215
T20 Burn and corrosion of head and neck	0.783	0.217
C51-C58 Malignant neoplasms of female genital organs	0.782	0.218
M86 Osteomyelitis	0.782	0.218
M54.57 Low back pain (Lumbosacral region)	0.782	0.218
M49 Spondylopathies in diseases classified elsewhere	0.782	0.218
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.781	0.219
S31 Open wound of abdomen, lower back and pelvis	0.779	0.221
S12 Fracture of neck	0.777	0.223
S82.21 Fracture of shaft of tibia (open)	0.773	0.227
T78.2 Anaphylactic shock, unspecified	0.771	0.229
H60.5 Acute otitis externa, non-infective	0.769	0.231
M46.9 Inflammatory spondylopathy, unspecified	0.769	0.231
M80-M85 Disorders of bone density and structure	0.769	0.231
E21.3 Hyperparathyroidism, unspecified	0.769	0.231
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.769	0.231
M60-M63 Disorders of muscles	0.767	0.233
H60.1 Cellulitis of external ear	0.767	0.233
H66.9 Otitis media, unspecified	0.763	0.237
M91-M94 Chondropathies	0.759	0.241
M48 Other spondylopathies	0.758	0.242
S82.20 Fracture of shaft of tibia (closed)	0.755	0.245
H74 Other disorders of middle ear and mastoid	0.755	0.245
C23 Malignant neoplasm of gallbladder	0.754	0.246
C17 Malignant neoplasm of small intestine	0.754	0.246
S82.0 Fracture of patella	0.751	0.249
Q80-Q89 Other congenital malformations	0.750	0.250
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.750	0.250
T83.0 Mechanical complication of urinary (indwelling) catheter	0.747	0.253
E28 Ovarian dysfunction	0.747	0.253
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.747	0.253
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.746	0.254
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.745	0.255
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.744	0.255
E34 Other endocrine disorders	0.744	0.256
S82.60 Fracture of lateral malleolus (closed)	0.744	0.256
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.743	0.257
S52.0 Fracture of upper end of ulna	0.741	0.259
T15-T19 Effects of foreign body entering through natural orifice	0.739	0.261
T36-T50 Poisoning by drugs, medicaments and biological substances	0.737	0.263
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.736	0.264
H18.9 Disorder of cornea, unspecified	0.735	0.265
M54.55 Low back pain (Thoracolumbar region)	0.735	0.265
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.730	0.270
D09 Carcinoma in situ of other and unspecified sites	0.730	0.270
E29 Testicular dysfunction	0.729	0.271
S80 Superficial injury of lower leg	0.729	0.271
S90 Superficial injury of ankle and foot	0.729	0.271
W20-W49 Exposure to inanimate mechanical forces	0.729	0.271
S52.1 Fracture of upper end of radius	0.728	0.272
M47.96 Spondylosis, unspecified (Lumbar region)	0.728	0.272
H35.4 Peripheral retinal degeneration	0.727	0.273
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.727	0.273
S20-S29 Injuries to the thorax	0.726	0.273
W00-W19 Falls	0.726	0.274
C55 Malignant neoplasm of uterus, part unspecified	0.726	0.274
Q50-Q56 Congenital malformations of genital organs	0.725	0.275
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.724	0.276
C18.7 Sigmoid colon	0.723	0.277
D37-D48 Neoplasms of uncertain or unknown behaviour	0.722	0.278
M54.1 Radiculopathy	0.722	0.278
T21 Burn and corrosion of trunk	0.721	0.279
D06 Carcinoma in situ of cervix uteri	0.720	0.280
T14 Injury of unspecified body region	0.720	0.280
M53 Other dorsopathies, not elsewhere classified	0.720	0.280
S14 Injury of nerves and spinal cord at neck level	0.720	0.280
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M54.8 Other dorsalgia	0.717	0.283
M54.0 Panniculitis affecting regions of neck and back	0.717	0.283
M79.0 Rheumatism, unspecified	0.712	0.288
S82.7 Multiple fractures of lower leg	0.712	0.288
M47.0 Anterior spinal and vertebral artery compression syndromes	0.712	0.288
M54.38 Sciatica (Sacral and sacrococcygeal region)	0.711	0.289
M54.35 Sciatica (Thoracolumbar region)	0.711	0.289
M54.34 Sciatica-Thoracic	0.711	0.289
M54.33 Sciatica-Cervicothoracic	0.711	0.289
M54.32 Sciatica-Cervical	0.711	0.289
M54.31 Sciatica-Occipit-atl-axl	0.711	0.289
M54.30 Sciatica (Multiple sites in spine)	0.711	0.289
M00-M03 Infectious arthropathies	0.708	0.291
T78.0 Anaphylactic shock due to adverse food reaction	0.708	0.292
C18.4 Transverse colon	0.708	0.292
T78.1 Other adverse food reactions, not elsewhere classified	0.707	0.293
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.705	0.295
M54.54 Low back pain-Thoracic	0.705	0.295
M54.53 Low back pain-Cervicothoracic	0.705	0.295
M54.52 Low back pain-Cervical	0.705	0.295
M54.51 Low back pain-Occipit-atl-axl	0.705	0.295
T23 Burn and corrosion of wrist and hand	0.704	0.296
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.704	0.296
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.703	0.296
H70 Mastoiditis and related conditions	0.703	0.296
H68 Eustachian salpingitis and obstruction	0.703	0.296
H67 Otitis media in diseases classified elsewhere	0.703	0.296
T83.1 Mechanical complication of other urinary devices and implants	0.702	0.298
M86.9 Osteomyelitis, unspecified	0.701	0.299
E14 Unspecified diabetes mellitus	0.698	0.302
H33.5 Other retinal detachments	0.698	0.302
M54.94 Dorsalgia, unspecified (Thoracic region)	0.698	0.302
M84 Disorders of continuity of bone	0.698	0.302
H18.6 Keratoconus	0.698	0.302
D05 Carcinoma in situ of breast	0.697	0.302
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.697	0.303
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.697	0.303
M54.92 Dorsalgia, unspecified (Cervical region)	0.697	0.303
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.697	0.303
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.697	0.303
T79 Certain early complications of trauma, not elsewhere classified	0.697	0.303
M89 Other disorders of bone	0.697	0.303
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.696	0.303
H62 Disorders of external ear in diseases classified elsewhere	0.695	0.304
S86 Injury of muscle and tendon at lower leg level	0.694	0.305
H72.2 Other marginal perforations of tympanic membrane	0.694	0.306
H72.1 Attic perforation of tympanic membrane	0.694	0.306
E23 Hypofunction and other disorders of pituitary gland	0.691	0.309
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.691	0.309
M47.85 Other spondylosis (Thoracolumbar region)	0.691	0.309
M47.83 Other spondylosis (Cervicothoracic region)	0.691	0.309
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.691	0.309
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.691	0.309
Q35-Q37 Cleft lip and cleft palate	0.691	0.309
Q30-Q34 Congenital malformations of the respiratory system	0.691	0.309
T90 Sequelae of injuries of head	0.689	0.311
M54.37 Sciatica (Lumbosacral region)	0.688	0.312
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.687	0.313
T88.7 Unspecified adverse effect of drug or medicament	0.686	0.314
S88 Traumatic amputation of lower leg	0.686	0.314
S87 Crushing injury of lower leg	0.686	0.314
S85 Injury of blood vessels at lower leg level	0.686	0.314
S84 Injury of nerves at lower leg level	0.686	0.314
H31 Other disorders of choroid	0.686	0.314
H60.8 Other otitis externa	0.685	0.315
H60.4 Cholesteatoma of external ear	0.685	0.315
H60.2 Malignant otitis externa	0.685	0.315
H60.0 Abscess of external ear	0.685	0.315
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.685	0.315
M51.9 Intervertebral disk disorder, unspecified	0.685	0.315
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.685	0.315
E21.0 Primary hyperparathyroidism	0.685	0.315
Q24 Other congenital malformations of heart	0.684	0.316
H35.6 Retinal haemorrhage	0.684	0.316
E24 Cushing's syndrome	0.684	0.316
H71 Cholesteatoma of middle ear	0.684	0.316
C60-C63 Malignant neoplasms of male genital organs	0.682	0.318
T82.4 Mechanical complication of vascular dialysis catheter	0.682	0.318
M54.6 Pain in thoracic spine	0.682	0.318
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.681	0.319
S37 Injury of urinary and pelvic organs	0.681	0.319
S36 Injury of intra-abdominal organs	0.681	0.319
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.681	0.319
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.681	0.319
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.681	0.319
H35.9 Retinal disorder, unspecified	0.679	0.321
H73 Other disorders of tympanic membrane	0.678	0.321
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.678	0.322
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.678	0.322
T85.4 Mechanical complication of breast prosthesis and implant	0.678	0.322
H33.4 Traction detachment of retina	0.675	0.325
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.675	0.325
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.674	0.326
C01 Malignant neoplasm of base of tongue	0.674	0.326
Chapter XIV Diseases of the genitourinary system	0.672	0.328
D02 Carcinoma in situ of middle ear and respiratory system	0.671	0.329
D01 Carcinoma in situ of other and unspecified digestive organs	0.670	0.330
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.670	0.330
T78.3 Angioneurotic oedema	0.670	0.330
M79.5 Residual foreign body in soft tissue	0.670	0.330
M65-M68 Disorders of synovium and tendon	0.670	0.330
H33.1 Retinoschisis and retinal cysts	0.669	0.331
H35.7 Separation of retinal layers	0.669	0.331
H21 Other disorders of iris and ciliary body	0.669	0.331
H16.0 Corneal ulcer	0.668	0.332
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.668	0.332
N13 Obstructive and reflux uropathy	0.667	0.333
T31 Burns classified according to extent of body surface involved	0.667	0.333
C18.8 Overlapping lesion of colon	0.666	0.334
N10-N16 Renal tubulo-interstitial diseases	0.666	0.334
C40-C41 Malignant neoplasms of bone and articular cartilage	0.665	0.335
M79.09 Rheumatism, unspecified (Site unspecified)	0.664	0.336
T20.2 Burn of second degree of head and neck	0.664	0.336
M47.89 Other spondylosis (Site unspecified)	0.663	0.337
S52.10 Fracture of upper end of radius (closed)	0.663	0.337
S96 Injury of muscle and tendon at ankle and foot level	0.663	0.337
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.662	0.338
H94 Other disorders of ear in diseases classified elsewhere	0.662	0.338
S59 Other and unspecified injuries of forearm	0.661	0.339
S51 Open wound of forearm	0.661	0.339
C16 Malignant neoplasm of stomach	0.661	0.339
H32 Chorioretinal disorders in diseases classified elsewhere	0.661	0.339
H30 Chorioretinal inflammation	0.661	0.339
X60-X84 Intentional self-harm	0.660	0.340
E00-E07 Disorders of thyroid gland	0.660	0.340
S12.2 Fracture of other specified cervical vertebra	0.660	0.340
S30.0 Contusion of lower back and pelvis	0.657	0.343
Q60-Q64 Congenital malformations of the urinary system	0.657	0.343
M47.95 Spondylosis, unspecified (Thoracolumbar region)	0.657	0.343
M47.94 Spondylosis, unspecified (Thoracic region)	0.657	0.343
M47.93 Spondylosis, unspecified (Cervicothoracic region)	0.657	0.343
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)	0.657	0.343
S31.0 Open wound of lower back and pelvis	0.656	0.343
S52.00 Fracture of upper end of ulna (closed)	0.657	0.343
S70 Superficial injury of hip and thigh	0.656	0.344
S82.9 Fracture of lower leg, part unspecified	0.656	0.344
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.654	0.346
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.653	0.347
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.653	0.347
H25-H28 Disorders of lens	0.651	0.349
Q38 Other congenital malformations of tongue, mouth and pharynx	0.651	0.349
N70-N77 Inflammatory diseases of female pelvic organs	0.651	0.349
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.651	0.349
T25 Burn and corrosion of ankle and foot	0.650	0.350
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.650	0.350
T75 Effects of other external causes	0.650	0.350
T74 Maltreatment syndromes	0.650	0.350
T73 Effects of other deprivation	0.650	0.350
T70 Effects of air pressure and water pressure	0.650	0.350
T69 Other effects of reduced temperature	0.650	0.350
T67 Effects of heat and light	0.650	0.350
T71 Asphyxiation	0.650	0.350
T66 Unspecified effects of radiation	0.650	0.350
S32.7 Multiple fractures of lumbar spine and pelvis	0.649	0.351
H53-H54 Visual disturbances and blindness	0.649	0.351
Q07 Other congenital malformations of nervous system	0.648	0.352
E65-E68 Obesity and other hyperalimentation	0.648	0.352
C18.1 Appendix	0.646	0.354
S79 Other and unspecified injuries of hip and thigh	0.645	0.355
M79.6 Pain in limb	0.645	0.355
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.644	0.356
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.644	0.356
T87.4 Infection of amputation stump	0.644	0.356
M90 Osteopathies in diseases classified elsewhere	0.643	0.357
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.643	0.357
X40-X49 Accidental poisoning by and exposure to noxious substances	0.643	0.357
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.643	0.357
S90.9 Superficial injury of ankle and foot, unspecified	0.642	0.358
M47.97 Spondylosis, unspecified (Lumbosacral region)	0.642	0.358
S82.5 Fracture of medial malleolus	0.641	0.359
M54.2 Cervicalgia	0.641	0.359
S91 Open wound of ankle and foot	0.641	0.359
E35 Disorders of endocrine glands in diseases classified elsewhere	0.640	0.360
E32 Diseases of thymus	0.640	0.360
E31 Polyglandular dysfunction	0.640	0.360
E30 Disorders of puberty, not elsewhere classified	0.640	0.360
E25 Adrenogenital disorders	0.640	0.360
E20 Hypoparathyroidism	0.640	0.360
M47.1 Other spondylosis with myelopathy	0.639	0.361
S10 Superficial injury of neck	0.639	0.361
T14.0 Superficial injury of unspecified body region	0.639	0.361
S58 Traumatic amputation of forearm	0.638	0.362
S57 Crushing injury of forearm	0.638	0.362
S56 Injury of muscle and tendon at forearm level	0.638	0.362
S55 Injury of blood vessels at forearm level	0.638	0.362
S54 Injury of nerves at forearm level	0.638	0.362
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.638	0.362
H18.1 Bullous keratopathy	0.638	0.362
D03 Melanoma in situ	0.638	0.362
T88.9 Complication of surgical and medical care, unspecified	0.636	0.363
T88.5 Other complications of anaesthesia	0.636	0.363
T88.3 Malignant hyperthermia due to anaesthesis	0.636	0.363
T88.2 Shock due to anaesthesia	0.636	0.363
T88.1 Other complications following immunisation, not elsewhere classified	0.636	0.363
T88.0 Infection following immunisation	0.636	0.363
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.636	0.364
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.636	0.364
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.636	0.364
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.636	0.364
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.636	0.364
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.636	0.364
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.636	0.364
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.636	0.364
D09.0 Bladder	0.636	0.364
D07 Carcinoma in situ of other and unspecified genital organs	0.635	0.365
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.634	0.366
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.634	0.366
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.634	0.366
H15 Disorders of sclera	0.634	0.366
E13 Other specified diabetes mellitus	0.634	0.366
H90.0 Conductive hearing loss, bilateral	0.633	0.367
M71 Other bursopathies	0.633	0.367
S82.00 Fracture of patella (closed)	0.633	0.367
H69 Other disorders of Eustachian tube	0.633	0.367
H72.8 Other perforations of tympanic membrane	0.633	0.367
S81.0 Open wound of knee	0.632	0.368
S17 Crushing injury of neck	0.631	0.368
S15 Injury of blood vessels at neck level	0.631	0.368
S11 Open wound of neck	0.631	0.368
S18 Traumatic amputation at neck level	0.631	0.368
S16 Injury of muscle and tendon at neck level	0.631	0.368
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.631	0.369
S32.5 Fracture of pubis	0.629	0.371
S81.9 Open wound of lower leg, part unspecified	0.629	0.371
H35.2 Other proliferative retinopathy	0.629	0.371
T82.1 Mechanical complication of cardiac electronic device	0.628	0.371
M51.3 Other specified intervertebral disk degeneration	0.628	0.372
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.628	0.372
M51.4 Schmorl's nodes	0.628	0.372
Q43 Other congenital malformations of intestine	0.628	0.372
S32.4 Fracture of acetabulum	0.628	0.372
X58-X59 Accidental exposure to other and unspecified factors	0.628	0.372
V40-V49 Car occupant injured in transport accident	0.628	0.372
E11 Non-insulin-dependent diabetes mellitus	0.627	0.373
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.627	0.373
M49.5 Collapsed vertebra in diseases classified elsewhere	0.627	0.373
M45.X2 Ankylosing spondylitis (Cervical region)	0.626	0.374
E28.2 Polycystic ovarian syndrome	0.625	0.375
Y00-Y09 Assault	0.625	0.375
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.623	0.377
C62 Malignant neoplasm of testis	0.622	0.378
C18.5 Splenic flexure	0.622	0.378
M54.17 Radiculopathy (Lumbosacral region)	0.622	0.378
T82.0 Mechanical complication of heart valve prosthesis	0.621	0.379
S52.3 Fracture of shaft of radius	0.621	0.379
H35.1 Retinopathy of prematurity	0.621	0.379
H16.2 Keratoconjunctivitis	0.620	0.380
E26 Hyperaldosteronism	0.620	0.380
M46.8 Other specified inflammatory spondylopathies	0.620	0.380
M46.5 Other infective spondylopathies	0.620	0.380
M46.4 Discitis, unspecified	0.620	0.380
M46.3 Infection of intervertebral disk (pyogenic)	0.620	0.380
M46.2 Osteomyelitis of vertebra	0.620	0.380
M46.1 Sacro-iliitis, not elsewhere classified	0.620	0.380
M46.0 Spinal enthesopathy	0.620	0.380
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.620	0.380
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.620	0.380
T90.9 Sequelae of unspecified injury of head	0.620	0.380
D06.9 Cervix, unspecified	0.619	0.381
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.618	0.382
W49 Exposure to other and unspecified inanimate mechanical forces	0.618	0.382
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.618	0.382
T20.0 Burn of unspecified degree of head and neck	0.617	0.382
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.617	0.383
C73 Malignant neoplasm of thyroid gland	0.617	0.383
M43 Other deforming dorsopathies	0.616	0.384
T78.9 Adverse effect, unspecified	0.616	0.384
T78.8 Other adverse effects, not elsewhere classified	0.616	0.384
S12.7 Multiple fractures of cervical spine	0.613	0.387
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.613	0.387
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.612	0.388
M51.2 Other specified intervertebral disk displacement	0.612	0.388
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.612	0.388
E29.1 Testicular hypofunction	0.612	0.388
H92 Otalgia and effusion of ear	0.612	0.388
W50-W64 Exposure to animate mechanical forces	0.611	0.388
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.611	0.389
M45.X9 Ankylosing spondylitis (Site unspecified)	0.610	0.390
S82.8 Fractures of other parts of lower leg	0.610	0.390
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.609	0.391
S82.4 Fracture of fibula alone	0.609	0.391
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.608	0.392
H18.8 Other specified disorders of cornea	0.608	0.392
H18.4 Corneal degeneration	0.608	0.392
E34.0 Carcinoid syndrome	0.608	0.392
M87 Osteonecrosis	0.608	0.392
M48.5 Collapsed vertebra, not elsewhere classified	0.607	0.393
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.607	0.393
C21 Malignant neoplasm of anus and anal canal	0.607	0.393
S98 Traumatic amputation of ankle and foot	0.607	0.393
S97 Crushing injury of ankle and foot	0.607	0.393
S95 Injury of blood vessels at ankle and foot level	0.607	0.393
S94 Injury of nerves at ankle and foot level	0.607	0.393
S32.3 Fracture of ilium	0.606	0.394
S40-S49 Injuries to the shoulder and upper arm	0.606	0.394
H16.9 Keratitis, unspecified	0.606	0.394
H35.0 Background retinopathy and retinal vascular changes	0.606	0.394
W05 Fall involving wheelchair	0.606	0.394
S89 Other and unspecified injuries of lower leg	0.605	0.395
S60-S69 Injuries to the wrist and hand	0.605	0.395
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.604	0.395
S30.2 Contusion of external genital organs	0.604	0.395
S14.1 Other and unspecified injuries of cervical spinal cord	0.604	0.396
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.604	0.396
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.604	0.396
S52.4 Fracture of shafts of both ulna and radius	0.604	0.396
E21.5 Disorder of parathyroid gland, unspecified	0.603	0.397
E21.4 Other specified disorders of parathyroid gland	0.603	0.397
E21.2 Other hyperparathyroidism	0.603	0.397
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.603	0.397
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.603	0.397
S52.01 Fracture of upper end of ulna (open)	0.602	0.398
H66.4 Suppurative otitis media, unspecified	0.601	0.399
H66.2 Chronic atticoantral suppurative otitis media	0.601	0.399
H66.1 Chronic tubotympanic suppurative otitis media	0.601	0.399
H66.0 Acute suppurative otitis media	0.601	0.399
Q05 Spina bifida	0.601	0.399
Y79 Orthopaedic devices associated with adverse incidents	0.601	0.399
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.601	0.399
E14.9 Without complications	0.601	0.399
Q24.9 Congenital malformation of the heart, unspecified	0.600	0.400
S52.2 Fracture of shaft of ulna	0.600	0.400
M62 Other disorders of muscle	0.600	0.400

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations