TreeWAS – Variant ID: rs79257513

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
M20-M25 Other joint disorders	1.000	0.000
M23 Internal derangement of knee	1.000	0.000
M23.2 Derangement of meniscus due to old tear or injury	1.000	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.999	0.001
N10-N16 Renal tubulo-interstitial diseases	0.998	0.002
N13 Obstructive and reflux uropathy	0.998	0.002
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.998	0.002
Chapter XIV Diseases of the genitourinary system	0.998	0.002
# Top node	0.997	0.003
N30-N39 Other diseases of urinary system	0.997	0.003
M25 Other joint disorders, not elsewhere classified	0.994	0.006
N32 Other disorders of bladder	0.993	0.007
M24 Other specific joint derangements	0.992	0.008
Chapter VI Diseases of the nervous system	0.987	0.013
N13.3 Other and unspecified hydronephrosis	0.985	0.015
M25.7 Osteophyte	0.984	0.016
N32.8 Other specified disorders of bladder	0.980	0.020
Chapter I Certain infectious and parasitic diseases	0.973	0.027
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.973	0.027
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.969	0.031
M24.1 Other articular cartilage disorders	0.966	0.034
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.960	0.040
N13.8 Other obstructive and reflux uropathy	0.956	0.044
M25.76 Osteophyte (Lower leg)	0.955	0.045
G80-G83 Cerebral palsy and other paralytic syndromes	0.935	0.065
N30 Cystitis	0.932	0.068
B95-B98 Bacterial, viral and other infectious agents	0.932	0.068
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.932	0.068
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.931	0.069
G20-G26 Extrapyramidal and movement disorders	0.931	0.069
M24.16 Other articular cartilage disorders (Lower leg)	0.927	0.073
M15-M19 Arthrosis	0.924	0.076
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.922	0.078
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.911	0.088
M24.0 Loose body in joint	0.911	0.089
N30.2 Other chronic cystitis	0.904	0.096
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.894	0.106
M25.4 Effusion of joint	0.887	0.113
N32.9 Bladder disorder, unspecified	0.881	0.119
N13.5 Kinking and stricture of ureter without hydronephrosis	0.881	0.119
G30-G32 Other degenerative diseases of the nervous system	0.877	0.123
M16 Coxarthrosis [arthrosis of hip]	0.872	0.128
M19 Other arthrosis	0.863	0.137
M86-M90 Other osteopathies	0.862	0.138
G24 Dystonia	0.859	0.141
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.859	0.141
T15-T19 Effects of foreign body entering through natural orifice	0.859	0.141
G80 Infantile cerebral palsy	0.857	0.143
M60-M63 Disorders of muscles	0.851	0.149
A00-A09 Intestinal infectious diseases	0.849	0.151
G90-G99 Other disorders of the nervous system	0.849	0.151
G20 Parkinson's disease	0.849	0.151
N32.3 Diverticulum of bladder	0.846	0.154
M23.3 Other meniscus derangements	0.840	0.160
Q20-Q28 Congenital malformations of the circulatory system	0.839	0.161
M25.75 Osteophyte (Pelvic region and thigh)	0.838	0.162
Q38-Q45 Other congenital malformations of the digestive system	0.838	0.162
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.833	0.167
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.832	0.168
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.830	0.170
M25.6 Stiffness of joint, not elsewhere classified	0.829	0.171
Chapter XV Pregnancy, childbirth and the puerperium	0.826	0.174
M16.9 Coxarthrosis, unspecified	0.824	0.176
M25.77 Osteophyte (Ankle and foot)	0.823	0.177
S60-S69 Injuries to the wrist and hand	0.823	0.177
S90-S99 Injuries to the ankle and foot	0.821	0.179
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.820	0.180
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.812	0.188
M25.8 Other specified joint disorders	0.812	0.188
B35-B49 Mycoses	0.812	0.188
M24.07 Loose body in joint (Ankle and foot)	0.810	0.190
G83 Other paralytic syndromes	0.807	0.193
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.806	0.194
T18 Foreign body in alimentary tract	0.802	0.198
Chapter XXII Codes for special purposes	0.802	0.198
M23.5 Chronic instability of knee	0.801	0.199
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.800	0.200
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.799	0.201
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.799	0.201
Q00-Q07 Congenital malformations of the nervous system	0.796	0.204
M23.8 Other internal derangements of knee	0.796	0.204
N32.0 Bladder-neck obstruction	0.795	0.205
M23.0 Cystic meniscus	0.794	0.206
M91-M94 Chondropathies	0.786	0.214
G82 Paraplegia and tetraplegia	0.785	0.215
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.783	0.217
M19.0 Primary arthrosis of other joints	0.783	0.217
G70-G73 Diseases of myoneural junction and muscle	0.783	0.217
G91 Hydrocephalus	0.782	0.218
N31.8 Other neuromuscular dysfunction of bladder	0.779	0.221
G24.9 Dystonia, unspecified	0.776	0.224
M24.13 Other articular cartilage disorders (Forearm)	0.776	0.224
M25.78 Osteophyte (Other)	0.776	0.224
M21 Other acquired deformities of limbs	0.776	0.224
N35 Urethral stricture	0.775	0.225
M24.2 Disorder of ligament	0.774	0.226
M45-M49 Spondylopathies	0.772	0.228
N34 Urethritis and urethral syndrome	0.771	0.228
M16.7 Other secondary coxarthrosis	0.771	0.229
G80.9 Infantile cerebral palsy, unspecified	0.771	0.229
N13.4 Hydroureter	0.771	0.229
O20-O29 Other maternal disorders predominantly related to pregnancy	0.769	0.231
Q50-Q56 Congenital malformations of genital organs	0.768	0.231
O94-O99 Other obstetric conditions, not elsewhere classified	0.767	0.233
G00-G09 Inflammatory diseases of the central nervous system	0.766	0.234
T18.1 Foreign body in oesophagus	0.761	0.239
M25.46 Effusion of joint (Lower leg)	0.761	0.239
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.759	0.241
M22 Disorders of patella	0.755	0.245
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.754	0.246
N99-N99 Other disorders of the genitourinary system	0.754	0.246
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.754	0.246
M23.6 Other spontaneous disruption of ligament(s) of knee	0.753	0.247
N25-N29 Other disorders of kidney and ureter	0.751	0.249
M25.74 Osteophyte (Hand)	0.751	0.249
M30 Polyarteritis nodosa and related conditions	0.747	0.253
M62 Other disorders of muscle	0.746	0.254
M19.9 Arthrosis, unspecified	0.746	0.254
Chapter XX External causes of morbidity and mortality	0.745	0.255
B50-B64 Protozoal diseases	0.743	0.257
M80-M85 Disorders of bone density and structure	0.741	0.258
M23.9 Internal derangement of knee, unspecified	0.741	0.259
M89 Other disorders of bone	0.740	0.260
M24.02 Loose body in joint (Upper arm)	0.740	0.260
M25.0 Haemarthrosis	0.739	0.260
M24.4 Recurrent dislocation and subluxation of joint	0.738	0.262
M25.47 Effusion of joint (Ankle and foot)	0.736	0.264
G35-G37 Demyelinating diseases of the central nervous system	0.735	0.265
B15-B19 Viral hepatitis	0.735	0.265
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.735	0.265
M25.71 Osteophyte (Shoulder region)	0.731	0.269
M25.3 Other instability of joint	0.731	0.269
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.726	0.274
Q38 Other congenital malformations of tongue, mouth and pharynx	0.726	0.274
B97 Viral agents as the cause of diseases classified to other chapters	0.726	0.274
B35 Dermatophytosis	0.725	0.275
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.724	0.276
T20-T25 Burns and corrosions of external body surface, specified by site	0.724	0.276
N11 Chronic tubulo-interstitial nephritis	0.722	0.277
N30.8 Other cystitis	0.721	0.279
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.721	0.279
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.719	0.281
Q76 Congenital malformations of spine and bony thorax	0.717	0.283
S66 Injury of muscle and tendon at wrist and hand level	0.717	0.283
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283
M33 Dermatopolymyositis	0.717	0.283
M32 Systemic lupus erythematosus	0.717	0.283
M23.1 Discoid meniscus (congenital)	0.717	0.283
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.717	0.283
G30 Alzheimer's disease	0.716	0.283
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.716	0.284
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.716	0.284
N15 Other renal tubulo-interstitial diseases	0.716	0.284
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.716	0.284
N13.7 Vesicoureteral-reflux-associated uropathy	0.715	0.284
T90 Sequelae of injuries of head	0.716	0.284
Chapter XVI Certain conditions originating in the perinatal period	0.715	0.285
N37 Urethral disorders in diseases classified elsewhere	0.715	0.285
N33 Bladder disorders in diseases classified elsewhere	0.715	0.285
T91 Sequelae of injuries of neck and trunk	0.714	0.286
G50-G59 Nerve, nerve root and plexus disorders	0.714	0.286
M25.2 Flail joint	0.713	0.287
M25.1 Fistula of joint	0.713	0.287
N32.4 Rupture of bladder, nontraumatic	0.712	0.288
N32.2 Vesical fistula, not elsewhere classified	0.712	0.288
T79-T79 Certain early complications of trauma	0.711	0.288
M24.9 Joint derangement, unspecified	0.711	0.289
M24.7 Protrusio acetabuli	0.711	0.289
M24.6 Ankylosis of joint	0.711	0.289
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.711	0.289
O85-O92 Complications predominantly related to the puerperium	0.710	0.290
G24.8 Other dystonia	0.710	0.290
N13.6 Pyonephrosis	0.706	0.293
M25.79 Osteophyte (Site unspecified)	0.706	0.294
M25.73 Osteophyte (Forearm)	0.706	0.294
M25.70 Osteophyte (Multiple sites)	0.706	0.294
G91.9 Hydrocephalus, unspecified	0.706	0.294
M24.8 Other specific joint derangements, not elsewhere classified	0.705	0.295
A08 Viral and other specified intestinal infections	0.704	0.296
N40-N51 Diseases of male genital organs	0.703	0.297
M88 Paget's disease of bone [osteitis deformans]	0.702	0.297
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.702	0.298
G80.1 Spastic diplegia	0.700	0.300
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.698	0.302
B85-B89 Pediculosis, acariasis and other infestations	0.698	0.302
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.698	0.302
A75-A79 Rickettsioses	0.698	0.302
A70-A74 Other diseases caused by chlamydiae	0.698	0.302
A65-A69 Other spirochaetal diseases	0.698	0.302
A20-A28 Certain zoonotic bacterial diseases	0.698	0.302
A15-A19 Tuberculosis	0.698	0.302
A04 Other bacterial intestinal infections	0.696	0.304
Q27 Other congenital malformations of peripheral vascular system	0.696	0.304
G93 Other disorders of brain	0.695	0.304
S10-S19 Injuries to the neck	0.695	0.305
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.695	0.305
Q35-Q37 Cleft lip and cleft palate	0.695	0.305
Q30-Q34 Congenital malformations of the respiratory system	0.695	0.305
M23.4 Loose body in knee	0.694	0.305
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.693	0.307
M24.19 Other articular cartilage disorders (Site unspecified)	0.693	0.307
M24.18 Other articular cartilage disorders (Other)	0.693	0.307
M24.14 Other articular cartilage disorders (Hand)	0.693	0.307
M24.12 Other articular cartilage disorders (Upper arm)	0.693	0.307
M24.10 Other articular cartilage disorders (Multiple sites)	0.693	0.307
N30.9 Cystitis, unspecified	0.691	0.309
S68 Traumatic amputation of wrist and hand	0.691	0.309
W20-W49 Exposure to inanimate mechanical forces	0.691	0.309
N36 Other disorders of urethra	0.691	0.309
M00-M03 Infectious arthropathies	0.690	0.309
S91 Open wound of ankle and foot	0.690	0.310
T94 Sequelae of injuries involving multiple and unspecified body regions	0.690	0.310
M24.01 Loose body in joint (Shoulder region)	0.690	0.310
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.689	0.311
S61 Open wound of wrist and hand	0.688	0.312
M24.5 Contracture of joint	0.686	0.314
M19.02 Primary arthrosis of other joints (Upper arm)	0.683	0.317
B00 Herpesviral [herpes simplex] infections	0.682	0.318
M16.5 Other posttraumatic coxarthrosis	0.681	0.319
T00-T07 Injuries involving multiple body regions	0.680	0.319
O26 Maternal care for other conditions predominantly related to pregnancy	0.680	0.320
G82.5 Tetraplegia, unspecified	0.679	0.321
N40 Hyperplasia of prostate	0.679	0.321
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.678	0.322
N35.8 Other urethral stricture	0.676	0.324
S40-S49 Injuries to the shoulder and upper arm	0.675	0.325
Chapter II Neoplasms	0.672	0.328
N30.1 Interstitial cystitis (chronic)	0.671	0.328
G56 Mononeuropathies of upper limb	0.671	0.329
M62.8 Other specified disorders of muscle	0.671	0.329
A30-A49 Other bacterial diseases	0.669	0.331
N30.4 Irradiation cystitis	0.668	0.332
T33-T35 Frostbite	0.668	0.332
T26-T28 Burns and corrosions confined to eye and internal organs	0.668	0.332
M24.17 Other articular cartilage disorders (Ankle and foot)	0.668	0.332
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.668	0.332
G23 Other degenerative diseases of basal ganglia	0.667	0.332
G21 Secondary Parkinsonism	0.667	0.332
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.667	0.332
G22 Parkinsonism in diseases classified elsewhere	0.667	0.332
M25.87 Other specified joint disorders (Ankle and foot)	0.666	0.334
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.664	0.336
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.664	0.336
M15 Polyarthrosis	0.663	0.337
Q23 Congenital malformations of aortic and mitral valves	0.662	0.338
B65-B83 Helminthiases	0.661	0.339
N10 Acute tubulo-interstitial nephritis	0.661	0.339
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.661	0.339
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.661	0.339
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.661	0.339
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.659	0.341
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.658	0.342
M34 Systemic sclerosis	0.657	0.343
M46 Other inflammatory spondylopathies	0.657	0.343
M24.21 Disorder of ligament (Shoulder region)	0.657	0.343
M35 Other systemic involvement of connective tissue	0.656	0.344
M19.01 Primary arthrosis of other joints (Shoulder region)	0.656	0.344
A80-A89 Viral infections of the central nervous system	0.655	0.345
B25-B34 Other viral diseases	0.654	0.346
O20 Haemorrhage in early pregnancy	0.654	0.346
M24.09 Loose body in joint (Site unspecified)	0.653	0.347
M24.08 Loose body in joint (Other)	0.653	0.347
M24.06 Loose body in joint-Lower leg	0.653	0.347
M24.05 Loose body in joint (Pelvic region and thigh)	0.653	0.347
M24.04 Loose body in joint (Hand)	0.653	0.347
M24.03 Loose body in joint (Forearm)	0.653	0.347
M24.00 Loose body in joint (Multiple sites)	0.653	0.347
B90-B94 Sequelae of infectious and parasitic diseases	0.653	0.347
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.653	0.347
Q60-Q64 Congenital malformations of the urinary system	0.652	0.348
B35.3 Tinea pedis	0.652	0.348
S32 Fracture of lumbar spine and pelvis	0.652	0.348
G70 Myasthenia gravis and other myoneural disorders	0.650	0.350
N13.9 Obstructive and reflux uropathy, unspecified	0.650	0.350
M19.92 Arthrosis, unspecified (Upper arm)	0.650	0.350
N30.0 Acute cystitis	0.649	0.351
G96 Other disorders of central nervous system	0.647	0.353
G83.4 Cauda equina syndrome	0.646	0.354
Q38.7 Pharyngeal pouch	0.646	0.354
C64-C68 Malignant neoplasms of urinary tract	0.645	0.355
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.645	0.355
B20-B24 Human immunodeficiency virus [HIV] disease	0.645	0.355
Q05 Spina bifida	0.643	0.356
M19.91 Arthrosis, unspecified (Shoulder region)	0.642	0.358
G31.9 Degenerative disease of nervous system, unspecified	0.641	0.359
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.641	0.359
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.640	0.360
C67 Malignant neoplasm of bladder	0.639	0.361
M49 Spondylopathies in diseases classified elsewhere	0.637	0.363
T17 Foreign body in respiratory tract	0.637	0.363
A02 Other Salmonella infections	0.637	0.363
M25.49 Effusion of joint (Site unspecified)	0.636	0.364
M25.48 Effusion of joint (Other)	0.636	0.364
M25.45 Effusion of joint (Pelvic region and thigh)	0.636	0.364
M25.44 Effusion of joint (Hand)	0.636	0.364
M25.43 Effusion of joint (Forearm)	0.636	0.364
M25.42 Effusion of joint (Upper arm)	0.636	0.364
M25.41 Effusion of joint (Shoulder region)	0.636	0.364
M25.40 Effusion of joint (Multiple sites)	0.636	0.364
M19.2 Other secondary arthrosis	0.635	0.365
B99-B99 Other infectious diseases	0.634	0.366
Q80-Q89 Other congenital malformations	0.634	0.366
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.633	0.367
M19.93 Arthrosis, unspecified (Forearm)	0.632	0.368
C67.9 Bladder, unspecified	0.632	0.368
D00-D09 In situ neoplasms	0.631	0.369
G56.0 Carpal tunnel syndrome	0.631	0.369
M25.9 Joint disorder, unspecified	0.630	0.370
G83.9 Paralytic syndrome, unspecified	0.630	0.370
M92 Other juvenile osteochondrosis	0.630	0.370
M85 Other disorders of bone density and structure	0.629	0.371
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.629	0.371
Q43 Other congenital malformations of intestine	0.627	0.372
S65 Injury of blood vessels at wrist and hand level	0.627	0.373
M16.6 Other secondary coxarthrosis, bilateral	0.625	0.375
M16.4 Posttraumatic coxarthrosis, bilateral	0.625	0.375
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.625	0.375
S67 Crushing injury of wrist and hand	0.625	0.375
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.624	0.376
B02 Zoster [herpes zoster]	0.624	0.376
U51 Admission status on psychiatric patients	0.624	0.376
M90 Osteopathies in diseases classified elsewhere	0.623	0.377
M40-M43 Deforming dorsopathies	0.622	0.378
Q21 Congenital malformations of cardiac septa	0.622	0.378
O26.9 Pregnancy-related condition, unspecified	0.620	0.380
M21.4 Flat foot [pes planus] (acquired)	0.619	0.380
Q28 Other congenital malformations of circulatory system	0.619	0.381
A50-A64 Infections with a predominantly sexual mode of transmission	0.619	0.381
S90 Superficial injury of ankle and foot	0.619	0.381
M19.8 Other specified arthrosis	0.619	0.381
S30 Superficial injury of abdomen, lower back and pelvis	0.619	0.381
G83.2 Monoplegia of upper limb	0.618	0.382
S64 Injury of nerves at wrist and hand level	0.618	0.382
N42 Other disorders of prostate	0.617	0.383
S00-S09 Injuries to the head	0.617	0.383
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.617	0.383
M19.97 Arthrosis, unspecified (Ankle and foot)	0.617	0.383
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.616	0.384
G24.5 Blepharospasm	0.616	0.384
G24.4 Idiopathic orofacial dystonia	0.616	0.384
G24.3 Spasmodic torticollis	0.616	0.384
G24.2 Idiopathic nonfamilial dystonia	0.616	0.384
G24.1 Idiopathic familial dystonia	0.616	0.384
G24.0 Drug-induced dystonia	0.616	0.384
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.616	0.384
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.616	0.384
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.616	0.384
M25.72 Osteophyte (Upper arm)	0.616	0.384
T19 Foreign body in genito-urinary tract	0.616	0.384
T15 Foreign body on external eye	0.616	0.384
T16 Foreign body in ear	0.616	0.384
M21.0 Valgus deformity, not elsewhere classified	0.616	0.384
M24.11 Other articular cartilage disorders (Shoulder region)	0.616	0.384
G80.8 Other infantile cerebral palsy	0.615	0.385
G80.4 Ataxic cerebral palsy	0.615	0.385
G80.3 Dyskinetic cerebral palsy	0.615	0.385
G80.2 Infantile hemiplegia	0.615	0.385
G80.0 Spastic cerebral palsy	0.615	0.385
O21 Excessive vomiting in pregnancy	0.615	0.385
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.614	0.386
Q07 Other congenital malformations of nervous system	0.614	0.386
S61.9 Open wound of wrist and hand, part unspecified	0.613	0.387
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.613	0.387
M89.8 Other specified disorders of bone	0.612	0.388
T66-T78 Other and unspecified effects of external causes	0.612	0.388
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.611	0.389
M63 Disorders of muscle in diseases classified elsewhere	0.610	0.390
M61 Calcification and ossification of muscle	0.610	0.390
M60 Myositis	0.610	0.390
B01 Varicella [chickenpox]	0.610	0.390
N34.2 Other urethritis	0.610	0.390
G91.1 Obstructive hydrocephalus	0.609	0.391
M80 Osteoporosis with pathological fracture	0.609	0.391
A07 Other protozoal intestinal diseases	0.609	0.391
A06 Amoebiasis	0.609	0.391
A05 Other bacterial foodborne intoxications	0.609	0.391
A03 Shigellosis	0.609	0.391
A01 Typhoid and paratyphoid fevers	0.609	0.391
A00 Cholera	0.609	0.391
G94 Other disorders of brain in diseases classified elsewhere	0.609	0.391
G98 Other disorders of nervous system, not elsewhere classified	0.609	0.391
G92 Toxic encephalopathy	0.609	0.391
S92 Fracture of foot, except ankle	0.608	0.391
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.608	0.392
M65-M68 Disorders of synovium and tendon	0.608	0.392
A04.8 Other specified bacterial intestinal infections	0.607	0.393
T36-T50 Poisoning by drugs, medicaments and biological substances	0.606	0.394
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.606	0.394
S37 Injury of urinary and pelvic organs	0.606	0.394
G83.8 Other specified paralytic syndromes	0.605	0.395
S09 Other and unspecified injuries of head	0.605	0.395
M89.5 Osteolysis	0.605	0.395
N32.1 Vesicointestinal fistula	0.605	0.395
G91.2 Normal-pressure hydrocephalus	0.605	0.395
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.604	0.396
T90.4 Sequelae of injury of eye and orbit	0.604	0.396
M19.03 Primary arthrosis of other joints (Forearm)	0.602	0.397
M93 Other osteochondropathies	0.602	0.398
M23.37 Other meniscus derangements-Capsular lig	0.602	0.398
G31.8 Other specified degenerative diseases of nervous system	0.602	0.398
Q26 Congenital malformations of great veins	0.602	0.398
Q25 Congenital malformations of great arteries	0.602	0.398
Q22 Congenital malformations of pulmonary and tricuspid valves	0.602	0.398
Q20 Congenital malformations of cardiac chambers and connexions	0.602	0.398
G30.9 Alzheimer's disease, unspecified	0.602	0.398
B44 Aspergillosis	0.601	0.398
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.601	0.399
O24 Diabetes mellitus in pregnancy	0.601	0.399
Q45 Other congenital malformations of digestive system	0.601	0.399
Q42 Congenital absence, atresia and stenosis of large intestine	0.601	0.399
Q41 Congenital absence, atresia and stenosis of small intestine	0.601	0.399
Q40 Other congenital malformations of upper alimentary tract	0.601	0.399
Q39 Congenital malformations of oesophagus	0.601	0.399
Q76.0 Spina bifida occulta	0.601	0.399
S69 Other and unspecified injuries of wrist and hand	0.600	0.400
Y00-Y09 Assault	0.598	0.402
G00 Bacterial meningitis, not elsewhere classified	0.597	0.403
Q24 Other congenital malformations of heart	0.597	0.403
Q66 Congenital deformities of feet	0.597	0.403
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.597	0.403
D07 Carcinoma in situ of other and unspecified genital organs	0.597	0.403
M86 Osteomyelitis	0.596	0.404
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.596	0.404
T95 Sequelae of burns, corrosions and frostbite	0.596	0.404
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.596	0.404
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.596	0.404
T98 Sequelae of other and unspecified effects of external causes	0.596	0.404
O90 Complications of the puerperium, not elsewhere classified	0.596	0.404
W25 Contact with sharp glass	0.596	0.404
M25.86 Other specified joint disorders (Lower leg)	0.595	0.405
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.594	0.406
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.594	0.406
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.594	0.406
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.594	0.406
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.594	0.406
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.594	0.406
M31 Other necrotising vasculopathies	0.593	0.406
S99 Other and unspecified injuries of ankle and foot	0.593	0.407
S09.9 Unspecified injury of head	0.593	0.407
Q27.3 Peripheral arteriovenous malformation	0.592	0.408
G93.0 Cerebral cysts	0.592	0.408
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.591	0.409
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.591	0.409
G82.2 Paraplegia, unspecified	0.591	0.409
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.590	0.410
M22.4 Chondromalacia patellae	0.590	0.410
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.589	0.411
S98 Traumatic amputation of ankle and foot	0.589	0.411
S97 Crushing injury of ankle and foot	0.589	0.411
S96 Injury of muscle and tendon at ankle and foot level	0.589	0.411
S95 Injury of blood vessels at ankle and foot level	0.589	0.411
S94 Injury of nerves at ankle and foot level	0.589	0.411
M88.9 Paget's disease of bone, unspecified	0.588	0.412
Q78 Other osteochondrodysplasias	0.588	0.412
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.588	0.412
Q75 Other congenital malformations of skull and face bones	0.588	0.412
Q74 Other congenital malformations of limb(s)	0.588	0.412
Q73 Reduction defects of unspecified limb	0.588	0.412
Q72 Reduction defects of lower limb	0.588	0.412
Q71 Reduction defects of upper limb	0.588	0.412
Q70 Syndactyly	0.588	0.412
Q69 Polydactyly	0.588	0.412
Q68 Other congenital musculoskeletal deformities	0.588	0.412
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.588	0.412
Q65 Congenital deformities of hip	0.588	0.412
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.588	0.412
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.588	0.412
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.588	0.412
T94.1 Sequelae of injuries, not specified by body region	0.588	0.412
S36 Injury of intra-abdominal organs	0.587	0.413
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.587	0.413
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.586	0.414
N41 Inflammatory diseases of prostate	0.585	0.415
T90.2 Sequelae of fracture of skull and facial bones	0.585	0.415
T91.3 Sequelae of injury of spinal cord	0.584	0.416
M25.36 Other instability of joint (Lower leg)	0.584	0.416
T91.1 Sequelae of fracture of spine	0.583	0.417
B06 Rubella [German measles]	0.582	0.417
B05 Measles	0.582	0.417
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.582	0.417
B04 Monkeypox	0.582	0.417
B03 Smallpox	0.582	0.417
M25.89 Other specified joint disorders (Site unspecified)	0.582	0.418
M25.88 Other specified joint disorders (Other)	0.582	0.418
M25.83 Other specified joint disorders (Forearm)	0.582	0.418
M25.82 Other specified joint disorders (Upper arm)	0.582	0.418
M25.80 Other specified joint disorders (Multiple sites)	0.582	0.418
B48 Other mycoses, not elsewhere classified	0.582	0.418
B47 Mycetoma	0.582	0.418
B46 Zygomycosis	0.582	0.418
B45 Cryptococcosis	0.582	0.418
B43 Chromomycosis and phaeomycotic abscess	0.582	0.418
B42 Sporotrichosis	0.582	0.418
B41 Paracoccidioidomycosis	0.582	0.418
B40 Blastomycosis	0.582	0.418
B39 Histoplasmosis	0.582	0.418
B38 Coccidioidomycosis	0.582	0.418
B36 Other superficial mycoses	0.582	0.418
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.582	0.418
W22 Striking against or struck by other objects	0.582	0.418

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations