TreeWAS – Variant ID: rs79336044

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter IX Diseases of the circulatory system	1.000	0.000
# Top node	1.000	0.000
I30-I52 Other forms of heart disease	1.000	0.000
I20-I25 Ischaemic heart diseases	1.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.998	0.002
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.997	0.003
Chapter V Mental and behavioural disorders	0.996	0.004
I70-I79 Diseases of arteries, arterioles and capillaries	0.994	0.006
I25.1 Atherosclerotic heart disease	0.994	0.006
I71 Aortic aneurysm and dissection	0.980	0.020
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.980	0.020
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.977	0.023
I35 Nonrheumatic aortic valve disorders	0.976	0.024
S60-S69 Injuries to the wrist and hand	0.973	0.027
F10 Mental and behavioural disorders due to use of alcohol	0.967	0.033
I50 Heart failure	0.966	0.034
I25.8 Other forms of chronic ischaemic heart disease	0.963	0.037
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.960	0.040
I44 Atrioventricular and left bundle-branch block	0.959	0.041
Chapter XX External causes of morbidity and mortality	0.958	0.042
T36-T50 Poisoning by drugs, medicaments and biological substances	0.953	0.047
I50.1 Left ventricular failure	0.949	0.051
O60-O75 Complications of labour and delivery	0.947	0.053
M05-M14 Inflammatory polyarthropathies	0.945	0.055
I44.7 Left bundle-branch block, unspecified	0.943	0.057
M80-M85 Disorders of bone density and structure	0.940	0.060
F40-F48 Neurotic, stress-related and somatoform disorders	0.932	0.068
Chapter VIII Diseases of the ear and mastoid process	0.929	0.071
I25.9 Chronic ischaemic heart disease, unspecified	0.929	0.071
F10.1 Harmful use	0.925	0.075
I35.0 Aortic (valve) stenosis	0.920	0.080
O80-O84 Delivery	0.918	0.082
I42 Cardiomyopathy	0.916	0.084
I21 Acute myocardial infarction	0.916	0.084
I72 Other aneurysm	0.909	0.091
M45-M49 Spondylopathies	0.907	0.093
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.907	0.093
S62 Fracture at wrist and hand level	0.896	0.104
M10 Gout	0.892	0.108
I31 Other diseases of pericardium	0.888	0.112
I46 Cardiac arrest	0.879	0.121
O80 Single spontaneous delivery	0.869	0.131
I05-I09 Chronic rheumatic heart diseases	0.868	0.132
F10.2 Dependence syndrome	0.868	0.132
I95-I99 Other and unspecified disorders of the circulatory system	0.864	0.136
M81 Osteoporosis without pathological fracture	0.863	0.137
I21.1 Acute transmural myocardial infarction of inferior wall	0.861	0.139
I25.2 Old myocardial infarction	0.859	0.141
M47 Spondylosis	0.859	0.141
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.858	0.142
M10.9 Gout, unspecified	0.855	0.145
I45 Other conduction disorders	0.855	0.145
S66 Injury of muscle and tendon at wrist and hand level	0.853	0.146
O69 Labour and delivery complicated by umbilical cord complications	0.852	0.148
Chapter VI Diseases of the nervous system	0.851	0.149
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.845	0.155
I20 Angina pectoris	0.842	0.158
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.839	0.161
F41 Other anxiety disorders	0.838	0.162
I31.9 Disease of pericardium, unspecified	0.837	0.163
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.837	0.163
I35.2 Aortic (valve) stenosis with insufficiency	0.835	0.165
I25.5 Ischaemic cardiomyopathy	0.835	0.165
M65-M68 Disorders of synovium and tendon	0.834	0.166
F40 Phobic anxiety disorders	0.833	0.167
O73 Retained placenta and membranes, without haemorrhage	0.832	0.168
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.825	0.174
M10.99 Gout, unspecified (Site unspecified)	0.823	0.177
I34 Nonrheumatic mitral valve disorders	0.821	0.179
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.820	0.180
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.818	0.182
Chapter II Neoplasms	0.815	0.185
H90-H95 Other disorders of ear	0.815	0.185
I50.9 Heart failure, unspecified	0.814	0.186
H65-H75 Diseases of middle ear and mastoid	0.812	0.188
I42.0 Dilated cardiomyopathy	0.812	0.188
I51 Complications and ill-defined descriptions of heart disease	0.811	0.189
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.806	0.194
Z95 Presence of cardiac and vascular implants and grafts	0.805	0.195
I21.0 Acute transmural myocardial infarction of anterior wall	0.804	0.196
Chapter XXI Factors influencing health status and contact with health services	0.803	0.197
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.803	0.197
X40-X49 Accidental poisoning by and exposure to noxious substances	0.801	0.199
I25.0 Atherosclerotic cardiovascular disease, so described	0.800	0.200
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.797	0.203
I46.0 Cardiac arrest with successful resuscitation	0.796	0.204
M81.9 Osteoporosis, unspecified	0.795	0.205
M47.8 Other spondylosis	0.795	0.205
C79 Secondary malignant neoplasm of other sites	0.793	0.207
S64 Injury of nerves at wrist and hand level	0.792	0.208
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.791	0.209
M05 Seropositive rheumatoid arthritis	0.788	0.212
Z95.8 Presence of other cardiac and vascular implants and grafts	0.787	0.213
Z92 Personal history of medical treatment	0.786	0.214
V10-V19 Pedal cyclist injured in transport accident	0.786	0.214
Z95.5 Presence of coronary angioplasty implant and graft	0.786	0.214
M85 Other disorders of bone density and structure	0.785	0.215
H92 Otalgia and effusion of ear	0.783	0.217
Z92.2 Personal history of long-term (current) use of other medicaments	0.781	0.219
I74 Arterial embolism and thrombosis	0.780	0.220
I71.0 Dissection of aorta [any part]	0.780	0.220
O80.0 Spontaneous vertex delivery	0.779	0.221
O46 Antepartum haemorrhage, not elsewhere classified	0.777	0.223
S10-S19 Injuries to the neck	0.776	0.224
I20.0 Unstable angina	0.775	0.225
M06 Other rheumatoid arthritis	0.774	0.226
I71.3 Abdominal aortic aneurysm, ruptured	0.774	0.226
I08 Multiple valve diseases	0.773	0.227
I25.3 Aneurysm of heart	0.773	0.227
O80.9 Single spontaneous delivery, unspecified	0.772	0.228
O20-O29 Other maternal disorders predominantly related to pregnancy	0.772	0.228
S20-S29 Injuries to the thorax	0.772	0.228
I72.3 Aneurysm of iliac artery	0.771	0.229
I35.1 Aortic (valve) insufficiency	0.770	0.230
T15-T19 Effects of foreign body entering through natural orifice	0.769	0.231
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.768	0.232
I77 Other disorders of arteries and arterioles	0.767	0.233
G90-G99 Other disorders of the nervous system	0.767	0.233
F10.3 Withdrawal state	0.767	0.233
F10.0 Acute intoxication	0.767	0.233
C79.8 Secondary malignant neoplasm of other specified sites	0.765	0.235
G50-G59 Nerve, nerve root and plexus disorders	0.764	0.236
Z95.1 Presence of aortocoronary bypass graft	0.764	0.236
F00-F09 Organic, including symptomatic, mental disorders	0.764	0.236
M47.86 Other spondylosis (Lumbar region)	0.763	0.237
F40.2 Specific (isolated) phobias	0.762	0.238
I72.4 Aneurysm of artery of lower extremity	0.762	0.238
O69.2 Labour and delivery complicated by other cord entanglement	0.761	0.239
H92.0 Otalgia	0.761	0.239
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.760	0.240
T42.4 Benzodiazepines	0.760	0.240
I35.9 Aortic valve disorder, unspecified	0.760	0.240
O42 Premature rupture of membranes	0.760	0.240
X60-X84 Intentional self-harm	0.759	0.241
I36 Nonrheumatic tricuspid valve disorders	0.758	0.242
I37 Pulmonary valve disorders	0.757	0.243
F12 Mental and behavioural disorders due to use of cannabinoids	0.755	0.244
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.754	0.246
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.751	0.249
M60-M63 Disorders of muscles	0.751	0.249
M47.2 Other spondylosis with radiculopathy	0.751	0.249
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.750	0.250
O73.0 Retained placenta, without haemorrhage	0.750	0.250
O68 Labour and delivery complicated by foetal stress [distress]	0.749	0.251
Chapter XXII Codes for special purposes	0.749	0.251
S62.8 Fracture of other and unspecified parts of wrist and hand	0.748	0.252
F80-F89 Disorders of psychological development	0.745	0.255
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.745	0.255
O61 Failed induction of labour	0.744	0.256
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.744	0.256
X20-X29 Contact with venomous animals and plants	0.742	0.258
M80 Osteoporosis with pathological fracture	0.741	0.259
F60-F69 Disorders of adult personality and behaviour	0.740	0.260
S60 Superficial injury of wrist and hand	0.740	0.260
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.737	0.263
W50-W64 Exposure to animate mechanical forces	0.736	0.264
S90-S99 Injuries to the ankle and foot	0.736	0.264
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.734	0.266
O00-O08 Pregnancy with abortive outcome	0.734	0.266
S62.6 Fracture of other finger	0.732	0.268
O35 Maternal care for known or suspected foetal abnormality and damage	0.731	0.269
W00-W19 Falls	0.730	0.269
O36 Maternal care for other known or suspected foetal problems	0.730	0.270
F41.2 Mixed anxiety and depressive disorder	0.730	0.270
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.729	0.271
F10.4 Withdrawal state with delirium	0.728	0.271
O62 Abnormalities of forces of labour	0.728	0.272
I45.6 Preexcitation syndrome	0.728	0.272
S61 Open wound of wrist and hand	0.728	0.272
I42.9 Cardiomyopathy, unspecified	0.728	0.272
S68 Traumatic amputation of wrist and hand	0.726	0.274
I70 Atherosclerosis	0.725	0.275
I47 Paroxysmal tachycardia	0.725	0.275
Z99.1 Dependence on respirator	0.724	0.276
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.723	0.277
H66 Suppurative and unspecified otitis media	0.722	0.278
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.722	0.278
I22 Subsequent myocardial infarction	0.721	0.279
M11 Other crystal arthropathies	0.721	0.279
I78 Diseases of capillaries	0.720	0.280
F99-F99 Unspecified mental disorder	0.720	0.280
S62.3 Fracture of other metacarpal bone	0.719	0.281
M84 Disorders of continuity of bone	0.719	0.281
O94-O99 Other obstetric conditions, not elsewhere classified	0.718	0.282
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.718	0.282
Z92.1 Personal history of long-term (current) use of anticoagulants	0.717	0.283
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283
I48 Atrial fibrillation and flutter	0.717	0.283
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283
I41 Myocarditis in diseases classified elsewhere	0.717	0.283
I40 Acute myocarditis	0.717	0.283
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283
I32 Pericarditis in diseases classified elsewhere	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I23 Certain current complications following acute myocardial infarction	0.717	0.283
I25.6 Silent myocardial ischaemia	0.717	0.283
I25.4 Coronary artery aneurysm	0.717	0.283
O85-O92 Complications predominantly related to the puerperium	0.715	0.285
T33-T35 Frostbite	0.715	0.285
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.285
T20-T25 Burns and corrosions of external body surface, specified by site	0.715	0.285
T00-T07 Injuries involving multiple body regions	0.715	0.285
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.714	0.286
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.714	0.286
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.714	0.286
F70-F79 Mental retardation	0.714	0.286
G20-G26 Extrapyramidal and movement disorders	0.713	0.287
I51.7 Cardiomegaly	0.713	0.287
I95 Hypotension	0.713	0.287
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.713	0.287
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.713	0.287
I72.8 Aneurysm of other specified arteries	0.711	0.289
C51-C58 Malignant neoplasms of female genital organs	0.710	0.290
O43 Placental disorders	0.708	0.292
C43-C44 Melanoma and other malignant neoplasms of skin	0.706	0.294
Q20-Q28 Congenital malformations of the circulatory system	0.705	0.295
O41 Other disorders of amniotic fluid and membranes	0.705	0.295
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.705	0.295
T79-T79 Certain early complications of trauma	0.704	0.296
M07 Psoriatic and enteropathic arthropathies	0.704	0.296
I30 Acute pericarditis	0.703	0.297
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.703	0.297
I71.8 Aortic aneurysm of unspecified site, ruptured	0.702	0.297
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.702	0.297
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.702	0.297
I71.1 Thoracic aortic aneurysm, ruptured	0.702	0.297
M00-M03 Infectious arthropathies	0.702	0.298
I38 Endocarditis, valve unspecified	0.701	0.299
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.701	0.299
F18 Mental and behavioural disorders due to use of volatile solvents	0.701	0.299
F16 Mental and behavioural disorders due to use of hallucinogens	0.701	0.299
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.701	0.299
F14 Mental and behavioural disorders due to use of cocaine	0.701	0.299
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.701	0.299
F11 Mental and behavioural disorders due to use of opioids	0.701	0.299
G57 Mononeuropathies of lower limb	0.700	0.300
H80-H83 Diseases of inner ear	0.700	0.300
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.698	0.302
S67 Crushing injury of wrist and hand	0.698	0.302
S65 Injury of blood vessels at wrist and hand level	0.698	0.302
T51 Toxic effect of alcohol	0.696	0.303
M91-M94 Chondropathies	0.696	0.304
I35.8 Other aortic valve disorders	0.696	0.304
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.696	0.304
I42.1 Obstructive hypertrophic cardiomyopathy	0.695	0.305
F30-F39 Mood [affective] disorders	0.695	0.305
F10.9 Unspecified mental and behavioural disorder	0.693	0.306
F10.8 Other mental and behavioural disorders	0.693	0.306
F10.7 Residual and late-onset psychotic disorder	0.693	0.306
F10.6 Amnesic syndrome	0.693	0.306
F10.5 Psychotic disorder	0.693	0.306
I34.0 Mitral (valve) insufficiency	0.694	0.306
W20-W49 Exposure to inanimate mechanical forces	0.693	0.307
O64 Obstructed labour due to malposition and malpresentation of foetus	0.692	0.307
Y52 Agents primarily affecting the cardiovascular system	0.692	0.308
T66-T78 Other and unspecified effects of external causes	0.692	0.308
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.690	0.310
M65 Synovitis and tenosynovitis	0.689	0.311
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.689	0.311
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.689	0.311
O72 Postpartum haemorrhage	0.688	0.312
I44.6 Other and unspecified fascicular block	0.688	0.312
I44.5 Left posterior fascicular block	0.688	0.312
I44.4 Left anterior fascicular block	0.688	0.312
I44.3 Other and unspecified atrioventricular block	0.688	0.312
T85 Complications of other internal prosthetic devices, implants and grafts	0.687	0.313
Y35-Y36 Legal intervention and operations of war	0.687	0.313
Y10-Y34 Event of undetermined intent	0.687	0.313
Y00-Y09 Assault	0.687	0.313
X85-X99 Assault	0.687	0.313
X58-X59 Accidental exposure to other and unspecified factors	0.687	0.313
X50-X57 Overexertion, travel and privation	0.687	0.313
X30-X39 Exposure to forces of nature	0.687	0.313
X10-X19 Contact with heat and hot substances	0.687	0.313
X00-X09 Exposure to smoke, fire and flames	0.687	0.313
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.687	0.313
W75-W84 Other accidental threats to breathing	0.687	0.313
W65-W74 Accidental drowning and submersion	0.687	0.313
V98-V99 Other and unspecified transport accidents	0.687	0.313
V95-V97 Air and space transport accidents	0.687	0.313
V90-V94 Water transport accidents	0.687	0.313
V70-V79 Bus occupant injured in transport accident	0.687	0.313
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.687	0.313
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.687	0.313
V40-V49 Car occupant injured in transport accident	0.687	0.313
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.687	0.313
V01-V09 Pedestrian injured in transport accident	0.687	0.313
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.686	0.314
I44.2 Atrioventricular block, complete	0.685	0.315
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.684	0.315
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.683	0.316
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.683	0.316
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.683	0.316
T46 Poisoning by agents primarily affecting the cardiovascular system	0.683	0.316
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.683	0.316
T41 Poisoning by anaesthetics and therapeutic gases	0.683	0.316
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.683	0.316
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.683	0.316
T36 Poisoning by systemic antibiotics	0.683	0.316
O46.9 Antepartum haemorrhage, unspecified	0.683	0.317
I45.2 Bifascicular block	0.683	0.317
T43.3 Phenothiazine antipsychotics and neuroleptics	0.683	0.317
O40 Polyhydramnios	0.682	0.318
V80-V89 Other land transport accidents	0.681	0.318
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.681	0.319
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.680	0.320
S70-S79 Injuries to the hip and thigh	0.680	0.320
O74 Complications of anaesthesia during labour and delivery	0.679	0.321
O71 Other obstetric trauma	0.679	0.321
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.679	0.321
O65 Obstructed labour due to maternal pelvic abnormality	0.679	0.321
O60 Preterm delivery	0.679	0.321
I42.2 Other hypertrophic cardiomyopathy	0.678	0.322
M14 Arthropathies in other diseases classified elsewhere	0.677	0.323
M12 Other specific arthropathies	0.677	0.323
M09 Juvenile arthritis in diseases classified elsewhere	0.677	0.323
M08 Juvenile arthritis	0.677	0.323
M81.98 Osteoporosis, unspecified (Other)	0.676	0.324
M05.9 Seropositive rheumatoid arthritis, unspecified	0.676	0.324
Y51 Drugs primarily affecting the autonomic nervous system	0.674	0.326
I21.2 Acute transmural myocardial infarction of other sites	0.674	0.326
M83 Adult osteomalacia	0.674	0.326
M82 Osteoporosis in diseases classified elsewhere	0.674	0.326
S62.5 Fracture of thumb	0.674	0.326
S50-S59 Injuries to the elbow and forearm	0.672	0.328
M48 Other spondylopathies	0.670	0.330
I33 Acute and subacute endocarditis	0.670	0.330
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.670	0.330
S64.0 Injury of ulnar nerve at wrist and hand level	0.668	0.332
T91 Sequelae of injuries of neck and trunk	0.668	0.332
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.668	0.332
F48 Other neurotic disorders	0.668	0.332
F44 Dissociative [conversion] disorders	0.668	0.332
F42 Obsessive-compulsive disorder	0.668	0.332
O63 Long labour	0.668	0.332
I08.0 Disorders of both mitral and aortic valves	0.668	0.332
T43.2 Other and unspecified antidepressants	0.666	0.334
I05 Rheumatic mitral valve diseases	0.666	0.334
Z70-Z76 Persons encountering health services in other circumstances	0.664	0.336
I60-I69 Cerebrovascular diseases	0.664	0.336
M81.4 Drug-induced osteoporosis	0.663	0.336
V18 Pedal cyclist injured in noncollision transport accident	0.663	0.337
S69 Other and unspecified injuries of wrist and hand	0.662	0.338
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.662	0.338
G99 Other disorders of nervous system in diseases classified elsewhere	0.661	0.338
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.660	0.340
M85.8 Other specified disorders of bone density and structure	0.659	0.341
O84 Multiple delivery	0.658	0.342
O83 Other assisted single delivery	0.658	0.342
O81 Single delivery by forceps and vacuum extractor	0.658	0.342
I42.8 Other cardiomyopathies	0.657	0.343
I42.7 Cardiomyopathy due to drugs and other external agents	0.657	0.343
I42.6 Alcoholic cardiomyopathy	0.657	0.343
I42.5 Other restrictive cardiomyopathy	0.657	0.343
I42.4 Endocardial fibroelastosis	0.657	0.343
I42.3 Endomyocardial (eosinophilic) disease	0.657	0.343
M66 Spontaneous rupture of synovium and tendon	0.657	0.343
I21.X Presumed acute myicardial infaction (unconfirmed)	0.657	0.343
I21.3 Acute transmural myocardial infarction of unspecified site	0.657	0.343
S62.2 Fracture of first metacarpal bone	0.655	0.345
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.655	0.345
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.654	0.346
I44.0 Atrioventricular block, first degree	0.653	0.347
G00-G09 Inflammatory diseases of the central nervous system	0.653	0.347
I21.4 Acute subendocardial myocardial infarction	0.652	0.348
I72.9 Aneurysm of unspecified site	0.652	0.348
I72.6 Aneurysm and dissection of vertebral artery	0.652	0.348
I72.5 Aneurysm and dissection of other precerebral arteries	0.652	0.348
I72.2 Aneurysm of renal artery	0.652	0.348
I72.1 Aneurysm of artery of upper extremity	0.652	0.348
I72.0 Aneurysm of carotid artery	0.652	0.348
C79.9 Secondary malignant neoplasm, unspecified site	0.651	0.349
V20-V29 Motorcycle rider injured in transport accident	0.651	0.349
I98 Other disorders of circulatory system in diseases classified elsewhere	0.651	0.349
M49 Spondylopathies in diseases classified elsewhere	0.650	0.350
O45 Premature separation of placenta [abruptio placentae]	0.650	0.350
O44 Placenta praevia	0.650	0.350
O33 Maternal care for known or suspected disproportion	0.650	0.350
O31 Complications specific to multiple gestation	0.650	0.350
O36.5 Maternal care for poor foetal growth	0.647	0.353
O32 Maternal care for known or suspected malpresentation of foetus	0.647	0.353
O69.8 Labour and delivery complicated by other cord complications	0.646	0.353
Z98 Other postsurgical states	0.646	0.354
M06.3 Rheumatoid nodule	0.646	0.354
Z92.0 Personal history of contraception	0.646	0.354
I51.0 Cardiac septal defect, acquired	0.643	0.357
T59 Toxic effect of other gases, fumes and vapours	0.643	0.357
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.643	0.357
F41.9 Anxiety disorder, unspecified	0.643	0.357
O69.1 Labour and delivery complicated by cord around neck, with compression	0.643	0.357
O66 Other obstructed labour	0.642	0.358
S62.7 Multiple fractures of fingers	0.642	0.358
S62.4 Multiple fractures of metacarpal bones	0.642	0.358
S62.1 Fracture of other carpal bone(s)	0.642	0.358
S62.0 Fracture of navicular [scaphoid] bone of hand	0.642	0.358
G95 Other diseases of spinal cord	0.642	0.358
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.642	0.358
G24 Dystonia	0.641	0.359
G51 Facial nerve disorders	0.640	0.359
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.640	0.360
M10.4 Other secondary gout	0.640	0.360
M10.3 Gout due to impairment of renal function	0.640	0.360
M10.2 Drug-induced gout	0.640	0.360
M10.1 Lead-induced gout	0.640	0.360
M10.0 Idiopathic gout	0.640	0.360
Z99.3 Dependence on wheelchair	0.640	0.360
M46 Other inflammatory spondylopathies	0.638	0.362
M86-M90 Other osteopathies	0.637	0.363
I31.8 Other specified diseases of pericardium	0.636	0.363
I31.2 Haemopericardium, not elsewhere classified	0.636	0.363
I31.1 Chronic constrictive pericarditis	0.636	0.363
I31.0 Chronic adhesive pericarditis	0.636	0.363
C43 Malignant melanoma of skin	0.636	0.364
M81.90 Osteoporosis, unspecified (Multiple sites)	0.636	0.364
M10.97 Gout, unspecified (Ankle and foot)	0.636	0.364
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.635	0.365
D69 Purpura and other haemorrhagic conditions	0.635	0.365
Q80-Q89 Other congenital malformations	0.634	0.366
F03 Unspecified dementia	0.633	0.367
O42.9 Premature rupture of membranes, unspecified	0.633	0.367
M10.96 Gout, unspecified (Lower leg)	0.632	0.367
H60-H62 Diseases of external ear	0.632	0.368
H74 Other disorders of middle ear and mastoid	0.632	0.368
I10-I15 Hypertensive diseases	0.631	0.369
S62.60 Fracture of other finger (closed)	0.631	0.369
S22 Fracture of rib(s), sternum and thoracic spine	0.631	0.369
I46.1 Sudden cardiac death, so described	0.630	0.370
F45 Somatoform disorders	0.628	0.372
F43 Reaction to severe stress, and adjustment disorders	0.628	0.372
H66.9 Otitis media, unspecified	0.628	0.372
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.627	0.373
S64.3 Injury of digital nerve of thumb	0.627	0.373
M47.89 Other spondylosis (Site unspecified)	0.625	0.375
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.625	0.375
I45.5 Other specified heart block	0.625	0.375
G54 Nerve root and plexus disorders	0.625	0.375
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.624	0.375
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.623	0.377
O80.8 Other single spontaneous delivery	0.623	0.377
O80.1 Spontaneous breech delivery	0.623	0.377
I09 Other rheumatic heart diseases	0.622	0.377
I06 Rheumatic aortic valve diseases	0.622	0.377
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.620	0.379
O30 Multiple gestation	0.620	0.379
Z95.4 Presence of other heart-valve replacement	0.620	0.379
Q50-Q56 Congenital malformations of genital organs	0.620	0.380
M45 Ankylosing spondylitis	0.620	0.380
D69.6 Thrombocytopenia, unspecified	0.620	0.380
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.620	0.380
I46.9 Cardiac arrest, unspecified	0.619	0.381
I99 Other and unspecified disorders of circulatory system	0.619	0.381
O82 Single delivery by Caesarean section	0.619	0.381
M81.8 Other osteoporosis	0.619	0.381
M81.6 Localised osteoporosis [Lequesne]	0.619	0.381
M81.5 Idiopathic osteoporosis	0.619	0.381
M81.3 Postsurgical malabsorption osteoporosis	0.619	0.381
M81.2 Osteoporosis of disuse	0.619	0.381
M81.1 Postoophorectomy osteoporosis	0.619	0.381
M81.0 Postmenopausal osteoporosis	0.619	0.381
O23 Infections of genito-urinary tract in pregnancy	0.618	0.382
I95.1 Orthostatic hypotension	0.618	0.382
Z92.4 Personal history of major surgery, not elsewhere classified	0.618	0.382
S19 Other and unspecified injuries of neck	0.617	0.383
H71 Cholesteatoma of middle ear	0.617	0.383
I47.2 Ventricular tachycardia	0.617	0.383
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.617	0.383
G91 Hydrocephalus	0.616	0.384
S40-S49 Injuries to the shoulder and upper arm	0.616	0.384
H69 Other disorders of Eustachian tube	0.616	0.384
M47.1 Other spondylosis with myelopathy	0.616	0.384
M47.0 Anterior spinal and vertebral artery compression syndromes	0.616	0.384
O75 Other complications of labour and delivery, not elsewhere classified	0.615	0.385
O15 Eclampsia	0.615	0.385
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.615	0.385
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.615	0.385
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.615	0.385
Q38-Q45 Other congenital malformations of the digestive system	0.615	0.385
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.613	0.387
M10.98 Gout, unspecified (Other)	0.613	0.387
M10.95 Gout, unspecified (Pelvic region and thigh)	0.613	0.387
M10.94 Gout, unspecified (Hand)	0.613	0.387
M10.93 Gout, unspecified (Forearm)	0.613	0.387
M10.92 Gout, unspecified (Upper arm)	0.613	0.387
M10.91 Gout, unspecified (Shoulder region)	0.613	0.387
M10.90 Gout, unspecified (Multiple sites)	0.613	0.387
I45.8 Other specified conduction disorders	0.613	0.387
I45.4 Nonspecific intraventricular block	0.613	0.387
I45.3 Trifascicular block	0.613	0.387
I45.0 Right fascicular block	0.613	0.387
M40-M43 Deforming dorsopathies	0.613	0.387
C77.4 Inguinal and lower limb lymph nodes	0.612	0.388
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.612	0.388
S66.8 Injury of other muscles and tendons at wrist and hand level	0.612	0.388
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.612	0.388
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.612	0.388
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.612	0.388
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.612	0.388
I20.9 Angina pectoris, unspecified	0.612	0.388

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations