TreeWAS – Variant ID: rs79508250

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.999	0.001
# Top node	0.997	0.003
T39.1 4-Aminophenol derivatives	0.996	0.004
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.985	0.015
Chapter XX External causes of morbidity and mortality	0.980	0.020
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.964	0.036
Chapter II Neoplasms	0.962	0.038
C15-C26 Malignant neoplasms of digestive organs	0.956	0.044
D37-D48 Neoplasms of uncertain or unknown behaviour	0.954	0.046
C18 Malignant neoplasm of colon	0.952	0.048
S80-S89 Injuries to the knee and lower leg	0.950	0.050
Chapter XV Pregnancy, childbirth and the puerperium	0.945	0.055
Chapter IX Diseases of the circulatory system	0.944	0.056
I95-I99 Other and unspecified disorders of the circulatory system	0.935	0.065
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.934	0.066
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.933	0.067
I95 Hypotension	0.932	0.068
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.930	0.070
O80-O84 Delivery	0.928	0.072
T51 Toxic effect of alcohol	0.928	0.072
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.927	0.073
I95.1 Orthostatic hypotension	0.926	0.074
T43.2 Other and unspecified antidepressants	0.925	0.075
S90-S99 Injuries to the ankle and foot	0.924	0.076
O80 Single spontaneous delivery	0.920	0.080
O80.9 Single spontaneous delivery, unspecified	0.914	0.086
D46 Myelodysplastic syndromes	0.911	0.089
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.910	0.090
T51.0 Ethanol	0.909	0.091
Chapter VIII Diseases of the ear and mastoid process	0.903	0.097
S82 Fracture of lower leg, including ankle	0.900	0.100
I05-I09 Chronic rheumatic heart diseases	0.900	0.100
Y60-Y69 Misadventures to patients during surgical and medical care	0.897	0.103
Chapter XXII Codes for special purposes	0.895	0.105
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.892	0.108
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.890	0.110
Chapter VI Diseases of the nervous system	0.884	0.116
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.882	0.118
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.882	0.118
C18.0 Caecum	0.881	0.119
D46.9 Myelodysplastic syndrome, unspecified	0.880	0.120
S82.2 Fracture of shaft of tibia	0.875	0.125
G20-G26 Extrapyramidal and movement disorders	0.874	0.126
T15-T19 Effects of foreign body entering through natural orifice	0.873	0.127
C18.9 Colon, unspecified	0.870	0.130
T43.5 Other and unspecified antipsychotics and neuroleptics	0.869	0.131
I07 Rheumatic tricuspid valve diseases	0.862	0.138
T43.0 Tricyclic and tetracyclic antidepressants	0.859	0.141
S10-S19 Injuries to the neck	0.856	0.144
G20 Parkinson's disease	0.854	0.146
I95.9 Hypotension, unspecified	0.853	0.147
T40.2 Other opioids	0.852	0.148
H65-H75 Diseases of middle ear and mastoid	0.848	0.152
S92 Fracture of foot, except ankle	0.840	0.160
C20 Malignant neoplasm of rectum	0.838	0.162
S82.20 Fracture of shaft of tibia (closed)	0.838	0.162
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.838	0.162
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.837	0.163
I07.1 Tricuspid insufficiency	0.835	0.165
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.827	0.173
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.820	0.180
O85-O92 Complications predominantly related to the puerperium	0.820	0.180
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.819	0.181
S82.6 Fracture of lateral malleolus	0.819	0.181
H71 Cholesteatoma of middle ear	0.818	0.182
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.818	0.182
W20-W49 Exposure to inanimate mechanical forces	0.818	0.182
O16 Unspecified maternal hypertension	0.815	0.185
C02 Malignant neoplasm of other and unspecified parts of tongue	0.814	0.186
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.814	0.186
Y52 Agents primarily affecting the cardiovascular system	0.813	0.187
S50-S59 Injuries to the elbow and forearm	0.811	0.189
S90 Superficial injury of ankle and foot	0.810	0.190
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.807	0.193
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.806	0.194
V70-V79 Bus occupant injured in transport accident	0.806	0.194
C23 Malignant neoplasm of gallbladder	0.801	0.199
D37.0 Lip, oral cavity and pharynx	0.800	0.199
S81 Open wound of lower leg	0.799	0.201
Q50-Q56 Congenital malformations of genital organs	0.796	0.204
G25 Other extrapyramidal and movement disorders	0.796	0.204
Y60.0 During surgical operation	0.794	0.206
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.794	0.206
D60-D64 Aplastic and other anaemias	0.794	0.206
X60-X84 Intentional self-harm	0.793	0.207
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.792	0.208
D37.7 Other digestive organs	0.792	0.208
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.791	0.208
C18.3 Hepatic flexure	0.791	0.209
X40-X49 Accidental poisoning by and exposure to noxious substances	0.791	0.209
T14 Injury of unspecified body region	0.790	0.209
C18.5 Splenic flexure	0.788	0.212
C18.4 Transverse colon	0.785	0.215
C18.8 Overlapping lesion of colon	0.785	0.215
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.784	0.216
C18.1 Appendix	0.782	0.218
O80.8 Other single spontaneous delivery	0.782	0.218
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.780	0.220
G00-G09 Inflammatory diseases of the central nervous system	0.779	0.221
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.779	0.221
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.778	0.222
T58 Toxic effect of carbon monoxide	0.775	0.225
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.773	0.227
S70-S79 Injuries to the hip and thigh	0.769	0.231
D37.4 Colon	0.769	0.231
T36 Poisoning by systemic antibiotics	0.763	0.237
S82.60 Fracture of lateral malleolus (closed)	0.761	0.239
T56 Toxic effect of metals	0.760	0.239
H80-H83 Diseases of inner ear	0.759	0.241
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.759	0.241
T43.6 Psychostimulants with abuse potential	0.759	0.241
Y44 Agents primarily affecting blood constituents	0.759	0.241
I27 Other pulmonary heart diseases	0.758	0.242
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.758	0.242
W50-W64 Exposure to animate mechanical forces	0.757	0.243
S82.21 Fracture of shaft of tibia (open)	0.756	0.244
S12 Fracture of neck	0.755	0.245
Chapter I Certain infectious and parasitic diseases	0.755	0.245
U51 Admission status on psychiatric patients	0.754	0.246
C02.1 Border of tongue	0.754	0.246
H73 Other disorders of tympanic membrane	0.751	0.249
Chapter V Mental and behavioural disorders	0.742	0.258
T43.4 Butyrophenone and thioxanthene neuroleptics	0.741	0.258
T18 Foreign body in alimentary tract	0.740	0.260
Y57 Other and unspecified drugs and medicaments	0.737	0.263
X58-X59 Accidental exposure to other and unspecified factors	0.736	0.264
G30-G32 Other degenerative diseases of the nervous system	0.733	0.267
T20-T25 Burns and corrosions of external body surface, specified by site	0.732	0.268
V01-V09 Pedestrian injured in transport accident	0.732	0.268
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.731	0.269
T00-T07 Injuries involving multiple body regions	0.731	0.269
O12.0 Gestational oedema	0.731	0.269
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.730	0.270
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.730	0.270
S90.9 Superficial injury of ankle and foot, unspecified	0.729	0.271
T40.6 Other and unspecified narcotics	0.729	0.271
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.729	0.271
S92.3 Fracture of metatarsal bone	0.728	0.272
V20-V29 Motorcycle rider injured in transport accident	0.728	0.272
F30-F39 Mood [affective] disorders	0.726	0.274
X10-X19 Contact with heat and hot substances	0.725	0.275
D70-D77 Other diseases of blood and blood-forming organs	0.724	0.276
V80-V89 Other land transport accidents	0.722	0.278
D47.2 Monoclonal gammopathy	0.722	0.278
I10-I15 Hypertensive diseases	0.722	0.278
S20-S29 Injuries to the thorax	0.721	0.279
C25 Malignant neoplasm of pancreas	0.721	0.279
C12 Malignant neoplasm of pyriform sinus	0.721	0.279
C18.7 Sigmoid colon	0.720	0.280
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.719	0.281
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.717	0.283
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.717	0.283
T41 Poisoning by anaesthetics and therapeutic gases	0.717	0.283
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
Y00-Y09 Assault	0.717	0.283
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.716	0.284
T39.4 Antirheumatics, not elsewhere classified	0.716	0.284
T39.2 Pyrazolone derivatives	0.716	0.284
S80 Superficial injury of lower leg	0.715	0.284
Chapter XVI Certain conditions originating in the perinatal period	0.715	0.285
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.715	0.285
T46 Poisoning by agents primarily affecting the cardiovascular system	0.714	0.285
T39.0 Salicylates	0.713	0.287
C17 Malignant neoplasm of small intestine	0.713	0.287
T14.0 Superficial injury of unspecified body region	0.711	0.289
G25.0 Essential tremor	0.710	0.290
Y52.1 Calcium-channel blockers	0.709	0.291
I27.2 Other secondary pulmonary hypertension	0.708	0.292
T43.9 Psychotropic drug, unspecified	0.706	0.293
T43.8 Other psychotropic drugs, not elsewhere classified	0.706	0.293
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.706	0.293
C26 Malignant neoplasm of other and ill-defined digestive organs	0.706	0.294
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.705	0.295
D48.5 Skin	0.704	0.296
D62 Acute posthaemorrhagic anaemia	0.703	0.297
Q54 Hypospadias	0.703	0.297
Q80-Q89 Other congenital malformations	0.703	0.297
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.703	0.297
Y35-Y36 Legal intervention and operations of war	0.702	0.297
Y10-Y34 Event of undetermined intent	0.702	0.297
X85-X99 Assault	0.702	0.297
X50-X57 Overexertion, travel and privation	0.702	0.297
X30-X39 Exposure to forces of nature	0.702	0.297
X00-X09 Exposure to smoke, fire and flames	0.702	0.297
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.702	0.297
W75-W84 Other accidental threats to breathing	0.702	0.297
W65-W74 Accidental drowning and submersion	0.702	0.297
V98-V99 Other and unspecified transport accidents	0.702	0.297
V95-V97 Air and space transport accidents	0.702	0.297
V90-V94 Water transport accidents	0.702	0.297
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.702	0.297
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.702	0.297
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.702	0.297
F31 Bipolar affective disorder	0.700	0.300
Q38-Q45 Other congenital malformations of the digestive system	0.695	0.305
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.695	0.305
O86 Other puerperal infections	0.694	0.305
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.693	0.307
S96 Injury of muscle and tendon at ankle and foot level	0.693	0.307
C09 Malignant neoplasm of tonsil	0.693	0.307
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.692	0.308
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.691	0.308
I08 Multiple valve diseases	0.691	0.309
T65 Toxic effect of other and unspecified substances	0.691	0.309
T62 Toxic effect of other noxious substances eaten as food	0.691	0.309
T61 Toxic effect of noxious substances eaten as seafood	0.691	0.309
T60 Toxic effect of pesticides	0.691	0.309
T57 Toxic effect of other inorganic substances	0.691	0.309
T54 Toxic effect of corrosive substances	0.691	0.309
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.691	0.309
T52 Toxic effect of organic solvents	0.691	0.309
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.691	0.309
T55 Toxic effect of soaps and detergents	0.691	0.309
U51.1 Previously admitted to a psychiatric hospital of the provider	0.690	0.310
C40-C41 Malignant neoplasms of bone and articular cartilage	0.689	0.310
T40.4 Other synthetic narcotics	0.686	0.314
C21 Malignant neoplasm of anus and anal canal	0.685	0.314
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.685	0.315
T13 Other injuries of lower limb, level unspecified	0.685	0.315
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.684	0.316
Y46 Antiepileptics and anti-Parkinsonism drugs	0.684	0.316
H81 Disorders of vestibular function	0.684	0.316
D37.2 Small intestine	0.683	0.316
T16 Foreign body in ear	0.681	0.319
S88 Traumatic amputation of lower leg	0.681	0.319
S87 Crushing injury of lower leg	0.681	0.319
S85 Injury of blood vessels at lower leg level	0.681	0.319
S84 Injury of nerves at lower leg level	0.681	0.319
V78 Bus occupant injured in noncollision transport accident	0.681	0.319
S12.2 Fracture of other specified cervical vertebra	0.681	0.319
D37.9 Digestive organ, unspecified	0.679	0.321
Q00-Q07 Congenital malformations of the nervous system	0.679	0.321
H74 Other disorders of middle ear and mastoid	0.677	0.323
S82.0 Fracture of patella	0.677	0.323
I00-I02 Acute rheumatic fever	0.677	0.323
Chapter XII Diseases of the skin and subcutaneous tissue	0.677	0.323
S30 Superficial injury of abdomen, lower back and pelvis	0.676	0.324
B02 Zoster [herpes zoster]	0.675	0.325
T59 Toxic effect of other gases, fumes and vapours	0.675	0.325
Y51 Drugs primarily affecting the autonomic nervous system	0.674	0.326
G01 Meningitis in bacterial diseases classified elsewhere	0.674	0.326
I60-I69 Cerebrovascular diseases	0.673	0.327
W22 Striking against or struck by other objects	0.672	0.328
G70-G73 Diseases of myoneural junction and muscle	0.672	0.328
S82.3 Fracture of lower end of tibia	0.671	0.329
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.670	0.330
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.670	0.330
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.670	0.330
Q35-Q37 Cleft lip and cleft palate	0.670	0.330
Q30-Q34 Congenital malformations of the respiratory system	0.670	0.330
D63 Anaemia in chronic diseases classified elsewhere	0.669	0.331
I95.8 Other hypotension	0.668	0.332
I95.0 Idiopathic hypotension	0.668	0.332
D37.6 Liver, gallbladder and bile ducts	0.668	0.332
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.667	0.333
S56 Injury of muscle and tendon at forearm level	0.667	0.333
O15 Eclampsia	0.667	0.333
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.667	0.333
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.667	0.333
S14 Injury of nerves and spinal cord at neck level	0.667	0.333
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.666	0.334
S51 Open wound of forearm	0.665	0.335
O84 Multiple delivery	0.665	0.335
O83 Other assisted single delivery	0.665	0.335
T51.8 Other alcohols	0.665	0.335
T51.3 Fusel oil	0.665	0.335
T51.2 2-Propanol	0.665	0.335
T51.1 Methanol	0.665	0.335
H69 Other disorders of Eustachian tube	0.665	0.335
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.665	0.335
T40.8 Lysergide [LSD]	0.665	0.335
T40.7 Cannabis (derivatives)	0.665	0.335
T40.5 Cocaine	0.665	0.335
T40.3 Methadone	0.665	0.335
T40.1 Heroin	0.665	0.335
T40.0 Opium	0.665	0.335
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.664	0.336
B07 Viral warts	0.664	0.336
Y44.2 Anticoagulants	0.663	0.337
S98 Traumatic amputation of ankle and foot	0.662	0.338
S97 Crushing injury of ankle and foot	0.662	0.338
S95 Injury of blood vessels at ankle and foot level	0.662	0.338
S94 Injury of nerves at ankle and foot level	0.662	0.338
Y48 Anaesthetics and therapeutic gases	0.662	0.338
Q60-Q64 Congenital malformations of the urinary system	0.662	0.338
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.661	0.339
Y42.5 Other oestrogens and progestogens	0.660	0.340
O14.9 Preeclampsia, unspecified	0.660	0.340
O80.1 Spontaneous breech delivery	0.659	0.341
W23 Caught, crushed, jammed or pinched in or between objects	0.659	0.341
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.658	0.342
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.657	0.343
S81.8 Open wound of other parts of lower leg	0.656	0.344
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.655	0.345
T17 Foreign body in respiratory tract	0.654	0.346
S11 Open wound of neck	0.654	0.346
W25 Contact with sharp glass	0.653	0.347
S92.0 Fracture of calcaneus	0.653	0.347
D46.7 Other myelodysplastic syndromes	0.653	0.347
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.653	0.347
D46.5 Refractory anaemia with multi-lineage dysplasia	0.653	0.347
D46.4 Refractory anaemia, unspecified	0.653	0.347
D46.3 Refractory anaemia with excess of blasts with transformation	0.653	0.347
D46.2 Refractory anaemia with excess of blasts	0.653	0.347
D46.1 Refractory anaemia with sideroblasts	0.653	0.347
D46.0 Refractory anaemia without sideroblasts, so stated	0.653	0.347
S99 Other and unspecified injuries of ankle and foot	0.653	0.347
S92.4 Fracture of great toe	0.653	0.347
D55-D59 Haemolytic anaemias	0.653	0.347
D37.3 Appendix	0.653	0.347
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.652	0.348
C10 Malignant neoplasm of oropharynx	0.651	0.348
V40-V49 Car occupant injured in transport accident	0.651	0.349
C92 Myeloid leukaemia	0.651	0.349
D73 Diseases of spleen	0.651	0.349
Y49 Psychotropic drugs, not elsewhere classified	0.650	0.350
U81 Agent resistant to vancomycin and related antibiotics	0.650	0.350
S92.30 Fracture of metatarsal bone (closed)	0.648	0.352
X20-X29 Contact with venomous animals and plants	0.648	0.352
H81.1 Benign paroxysmal vertigo	0.648	0.352
L50-L54 Urticaria and erythema	0.647	0.353
T79-T79 Certain early complications of trauma	0.647	0.353
D61 Other aplastic anaemias	0.646	0.354
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.646	0.354
S82.9 Fracture of lower leg, part unspecified	0.645	0.354
S82.7 Multiple fractures of lower leg	0.645	0.354
C83 Diffuse non-Hodgkin's lymphoma	0.645	0.355
I09 Other rheumatic heart diseases	0.645	0.355
I06 Rheumatic aortic valve diseases	0.645	0.355
S89 Other and unspecified injuries of lower leg	0.645	0.355
D37.1 Stomach	0.645	0.355
T11 Other injuries of upper limb, level unspecified	0.645	0.355
O94-O99 Other obstetric conditions, not elsewhere classified	0.644	0.356
H73.8 Other specified disorders of tympanic membrane	0.644	0.356
S86 Injury of muscle and tendon at lower leg level	0.643	0.356
T47.1 Other antacids and anti-gastric-secretion drugs	0.643	0.357
I05 Rheumatic mitral valve diseases	0.643	0.357
Y95 Nosocomial condition	0.643	0.357
Y65 Other misadventures during surgical and medical care	0.643	0.357
Y64 Contaminated medical or biological substances	0.643	0.357
Y63 Failure in dosage during surgical and medical care	0.643	0.357
Y62 Failure of sterile precautions during surgical and medical care	0.643	0.357
Y61 Foreign object accidentally left in body during surgical and medical care	0.643	0.357
Y69 Unspecified misadventure during surgical and medical care	0.643	0.357
Y66 Nonadministration of surgical and medical care	0.643	0.357
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.641	0.359
Y59 Other and unspecified vaccines and biological substances	0.639	0.360
Y58 Bacterial vaccines	0.639	0.360
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.639	0.360
Y53 Agents primarily affecting the gastro-intestinal system	0.639	0.360
Y50 Central nervous system stimulants, not elsewhere classified	0.639	0.360
Y47 Sedatives, hypnotics and antianxiety drugs	0.639	0.360
B02.9 Zoster without complication	0.639	0.361
T09 Other injuries of spine and trunk, level unspecified	0.638	0.362
T12.X1 Fracture of lower limb, level unspecified (open)	0.638	0.362
T12.X0 Fracture of lower limb, level unspecified (closed)	0.638	0.362
T12 Fracture of lower limb, level unspecified	0.638	0.362
T10.X1 Fracture of upper limb, level unspecified (open)	0.638	0.362
T10.X0 Fracture of upper limb, level unspecified (closed)	0.638	0.362
T10 Fracture of upper limb, level unspecified	0.638	0.362
T08.X1 Fracture of spine, level unspecified (open)	0.638	0.362
T08.X0 Fracture of spine, level unspecified (closed)	0.638	0.362
T08 Fracture of spine, level unspecified	0.638	0.362
I61 Intracerebral haemorrhage	0.636	0.364
D44.0 Thyroid gland	0.636	0.364
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.635	0.365
F32 Depressive episode	0.635	0.365
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.635	0.365
S54 Injury of nerves at forearm level	0.635	0.365
S92.1 Fracture of talus	0.634	0.366
S21 Open wound of thorax	0.634	0.366
G25.3 Myoclonus	0.634	0.366
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.633	0.367
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.633	0.367
C13 Malignant neoplasm of hypopharynx	0.633	0.367
C11 Malignant neoplasm of nasopharynx	0.633	0.367
C08 Malignant neoplasm of other and unspecified major salivary glands	0.633	0.367
C06 Malignant neoplasm of other and unspecified parts of mouth	0.633	0.367
C05 Malignant neoplasm of palate	0.633	0.367
C03 Malignant neoplasm of gum	0.633	0.367
C00 Malignant neoplasm of lip	0.633	0.367
I15 Secondary hypertension	0.633	0.367
Y57.5 X-ray contrast media	0.632	0.368
C04 Malignant neoplasm of floor of mouth	0.631	0.369
U51.0 Not Previously admitted to a psyciatric hospital	0.631	0.369
O92 Other disorders of breast and lactation associated with childbirth	0.630	0.370
L53 Other erythematous conditions	0.630	0.370
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.630	0.370
B25-B34 Other viral diseases	0.629	0.371
S12.20 Fracture of other specified cervical vertebra (closed)	0.627	0.372
D48.0 Bone and articular cartilage	0.627	0.373
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.627	0.373
Y52.4 Angiotensin-converting-enzyme inhibitors	0.627	0.373
D47.4 Osteomyelofibrosis	0.627	0.373
C84 Peripheral and cutaneous T-cell lymphomas	0.627	0.373
G23 Other degenerative diseases of basal ganglia	0.626	0.373
G21 Secondary Parkinsonism	0.626	0.373
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.626	0.373
G22 Parkinsonism in diseases classified elsewhere	0.626	0.373
C43-C44 Melanoma and other malignant neoplasms of skin	0.626	0.374
C02.9 Tongue, unspecified	0.626	0.374
T19 Foreign body in genito-urinary tract	0.626	0.374
T15 Foreign body on external eye	0.626	0.374
O14.0 Moderate preeclampsia	0.625	0.375
T43.3 Phenothiazine antipsychotics and neuroleptics	0.624	0.375
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.623	0.377
D48.7 Other specified sites	0.623	0.377
D48.1 Connective and other soft tissue	0.622	0.378
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.622	0.378
Q17 Other congenital malformations of ear	0.621	0.379
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.621	0.379
S81.9 Open wound of lower leg, part unspecified	0.621	0.379
S82.5 Fracture of medial malleolus	0.620	0.380
O82 Single delivery by Caesarean section	0.619	0.381
Q65 Congenital deformities of hip	0.619	0.381
I07.9 Tricuspid valve disease, unspecified	0.618	0.382
I07.8 Other tricuspid valve diseases	0.618	0.382
I07.2 Tricuspid stenosis with insufficiency	0.618	0.382
I07.0 Tricuspid stenosis	0.618	0.382
L53.9 Erythematous condition, unspecified	0.616	0.384
I97.2 Postmastectomy lymphoedema syndrome	0.616	0.384
T45.5 Anticoagulants	0.616	0.384
T18.1 Foreign body in oesophagus	0.616	0.384
D72 Other disorders of white blood cells	0.616	0.384
Q54.0 Hypospadias, balanic	0.615	0.384
H73.9 Disorder of tympanic membrane, unspecified	0.615	0.385
T56.8 Other metals	0.615	0.385
G06 Intracranial and intraspinal abscess and granuloma	0.615	0.385
F31.9 Bipolar affective disorder, unspecified	0.615	0.385
Q20-Q28 Congenital malformations of the circulatory system	0.614	0.386
S17 Crushing injury of neck	0.613	0.386
S15 Injury of blood vessels at neck level	0.613	0.386
S18 Traumatic amputation at neck level	0.613	0.386
S16 Injury of muscle and tendon at neck level	0.613	0.386
X47 Accidental poisoning by and exposure to other gases and vapours	0.613	0.387
O90 Complications of the puerperium, not elsewhere classified	0.612	0.388
O81 Single delivery by forceps and vacuum extractor	0.612	0.388
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.611	0.389
G90-G99 Other disorders of the nervous system	0.611	0.389
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.610	0.390
D73.0 Hyposplenism	0.610	0.390
Q18 Other congenital malformations of face and neck	0.610	0.390
W20 Struck by thrown, projected or falling object	0.609	0.391
I61.9 Intracerebral haemorrhage, unspecified	0.609	0.391
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.608	0.392
H68 Eustachian salpingitis and obstruction	0.608	0.392
H67 Otitis media in diseases classified elsewhere	0.608	0.392
Z50 Care involving use of rehabilitation procedures	0.608	0.392
I12 Hypertensive renal disease	0.607	0.393
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.606	0.394
S70 Superficial injury of hip and thigh	0.605	0.394
O86.0 Infection of obstetric surgical wound	0.605	0.395
Z40-Z54 Persons encountering health services for specific procedures and health care	0.604	0.396
T63 Toxic effect of contact with venomous animals	0.602	0.397
S92.9 Fracture of foot, unspecified	0.602	0.398
S92.7 Multiple fractures of foot	0.602	0.398
S92.5 Fracture of other toe	0.602	0.398
S92.2 Fracture of other tarsal bone(s)	0.602	0.398
A15-A19 Tuberculosis	0.602	0.398
G31.9 Degenerative disease of nervous system, unspecified	0.602	0.398
I27.8 Other specified pulmonary heart diseases	0.601	0.399
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.601	0.399
C95 Leukaemia of unspecified cell type	0.601	0.399
C94 Other leukaemias of specified cell type	0.601	0.399
C93 Monocytic leukaemia	0.601	0.399
C86 Other specified types of T/NK-cell lymphoma	0.601	0.399
Chapter XXI Factors influencing health status and contact with health services	0.600	0.400
Y60.9 During unspecified surgical and medical care	0.600	0.400
Y60.8 During other surgical and medical care	0.600	0.400
Y60.7 During administration of enema	0.600	0.400
Y60.6 During aspiration, puncture and other catheterisation	0.600	0.400
Y60.5 During heart catheterisation	0.600	0.400
Y60.4 During endoscopic examination	0.600	0.400
Y60.3 During injection or immunisation	0.600	0.400
Y60.2 During kidney dialysis or other perfusion	0.600	0.400
Y60.1 During infusion or transfusion	0.600	0.400
C15 Malignant neoplasm of oesophagus	0.599	0.400
F60-F69 Disorders of adult personality and behaviour	0.599	0.401
H70 Mastoiditis and related conditions	0.599	0.401
Q66 Congenital deformities of feet	0.599	0.401
F31.7 Bipolar affective disorder, currently in remission	0.596	0.404
B99-B99 Other infectious diseases	0.596	0.404
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.596	0.404
G25.8 Other specified extrapyramidal and movement disorders	0.596	0.404
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.595	0.404
O87 Venous complications in the puerperium	0.595	0.405
Z51 Other medical care	0.595	0.405
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.594	0.406
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.593	0.407
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.593	0.407
T42.5 Mixed antiepileptics, not elsewhere classified	0.593	0.407
T42.3 Barbiturates	0.593	0.407
T42.2 Succinimides and oxazolidinediones	0.593	0.407
T42.1 Iminostilbenes	0.593	0.407
T42.0 Hydantoin derivatives	0.593	0.407
T36.0 Penicillins	0.593	0.407

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations