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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79581221
log Bayes Factor = 9.13228
Chromosome 5   position 81,379,394  (GRCh37) Explore rs79581221 on Ensembl!
Variant rs79581221 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.994 0.006 0.000
O60-O75 Complications of labour and delivery
0.994 0.006 0.000
I20-I25 Ischaemic heart diseases
0.992 0.008 0.000
Chapter I Certain infectious and parasitic diseases
0.991 0.009 0.000
Chapter VI Diseases of the nervous system
0.991 0.009 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.988 0.012 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.987 0.013 0.000
I30-I52 Other forms of heart disease
0.981 0.019 0.000
M20-M25 Other joint disorders
0.981 0.019 0.000
E70-E90 Metabolic disorders
0.978 0.022 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.976 0.024 0.000
A00-A09 Intestinal infectious diseases
0.975 0.025 0.000
I25 Chronic ischaemic heart disease
0.973 0.027 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.970 0.030 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.967 0.033 0.000
I50 Heart failure
0.965 0.035 0.000
I60-I69 Cerebrovascular diseases
0.961 0.039 0.000
M20 Acquired deformities of fingers and toes
0.947 0.053 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.946 0.054 0.000
Chapter X Diseases of the respiratory system
0.928 0.072 0.000
I69 Sequelae of cerebrovascular disease
0.926 0.074 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.922 0.078 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.917 0.083 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.916 0.084 0.000
I71 Aortic aneurysm and dissection
0.916 0.084 0.000
I24 Other acute ischaemic heart diseases
0.911 0.089 0.000
M80-M85 Disorders of bone density and structure
0.909 0.091 0.000
I50.1 Left ventricular failure
0.904 0.096 0.000
E86 Volume depletion
0.896 0.104 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.894 0.106 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.891 0.109 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.888 0.112 0.000
M25 Other joint disorders, not elsewhere classified
0.887 0.113 0.000
I25.1 Atherosclerotic heart disease
0.876 0.124 0.000
I77 Other disorders of arteries and arterioles
0.873 0.127 0.000
I50.0 Congestive heart failure
0.868 0.132 0.000
I42 Cardiomyopathy
0.867 0.133 0.000
E10-E14 Diabetes mellitus
0.867 0.133 0.000
E83 Disorders of mineral metabolism
0.865 0.135 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.865 0.135 0.000
S20-S29 Injuries to the thorax
0.856 0.144 0.000
I44 Atrioventricular and left bundle-branch block
0.856 0.144 0.000
I74 Arterial embolism and thrombosis
0.855 0.145 0.000
G57 Mononeuropathies of lower limb
0.851 0.149 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.850 0.150 0.000
O63 Long labour
0.847 0.152 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.847 0.153 0.000
B95-B98 Bacterial, viral and other infectious agents
0.846 0.154 0.000
Chapter VII Diseases of the eye and adnexa
0.837 0.163 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.837 0.163 0.000
O62 Abnormalities of forces of labour
0.836 0.164 0.000
G56 Mononeuropathies of upper limb
0.834 0.166 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.831 0.169 0.000
I22 Subsequent myocardial infarction
0.830 0.170 0.000
M05-M14 Inflammatory polyarthropathies
0.830 0.170 0.000
M20.5 Other deformities of toe(s) (acquired)
0.829 0.171 0.000
J00-J06 Acute upper respiratory infections
0.827 0.173 0.000
G81 Hemiplegia
0.824 0.176 0.000
I73 Other peripheral vascular diseases
0.822 0.178 0.000
E20-E35 Disorders of other endocrine glands
0.816 0.184 0.000
I69.3 Sequelae of cerebral infarction
0.816 0.184 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.814 0.186 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.814 0.186 0.000
J09-J18 Influenza and pneumonia
0.813 0.187 0.000
M81 Osteoporosis without pathological fracture
0.813 0.187 0.000
J40-J47 Chronic lower respiratory diseases
0.812 0.188 0.000
I50.9 Heart failure, unspecified
0.812 0.188 0.000
M35 Other systemic involvement of connective tissue
0.811 0.189 0.000
E87.5 Hyperkalaemia
0.811 0.189 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.810 0.190 0.000
B65-B83 Helminthiases
0.810 0.190 0.000
M20.1 Hallux valgus (acquired)
0.806 0.194 0.000
I24.8 Other forms of acute ischaemic heart disease
0.804 0.196 0.000
O61 Failed induction of labour
0.803 0.197 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.801 0.199 0.000
E11 Non-insulin-dependent diabetes mellitus
0.797 0.203 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.797 0.203 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.795 0.205 0.000
E65-E68 Obesity and other hyperalimentation
0.795 0.205 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.790 0.210 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.789 0.211 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.788 0.212 0.000
J95-J99 Other diseases of the respiratory system
0.786 0.214 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.786 0.214 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.785 0.215 0.000
G57.6 Lesion of plantar nerve
0.784 0.216 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.783 0.217 0.000
I67 Other cerebrovascular diseases
0.782 0.218 0.000
J44 Other chronic obstructive pulmonary disease
0.777 0.223 0.000
E50-E64 Other nutritional deficiencies
0.775 0.225 0.000
G81.9 Hemiplegia, unspecified
0.775 0.225 0.000
M23 Internal derangement of knee
0.774 0.226 0.000
O16 Unspecified maternal hypertension
0.774 0.226 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.773 0.227 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.772 0.228 0.000
G56.2 Lesion of ulnar nerve
0.772 0.228 0.000
O70 Perineal laceration during delivery
0.768 0.232 0.000
I30 Acute pericarditis
0.767 0.233 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.766 0.234 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.764 0.236 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.763 0.237 0.000
S90-S99 Injuries to the ankle and foot
0.762 0.237 0.000
G30-G32 Other degenerative diseases of the nervous system
0.762 0.238 0.000
M25.5 Pain in joint
0.761 0.239 0.000
G20-G26 Extrapyramidal and movement disorders
0.760 0.240 0.000
S80-S89 Injuries to the knee and lower leg
0.759 0.240 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.758 0.242 0.000
O72 Postpartum haemorrhage
0.756 0.244 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.756 0.244 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.756 0.244 0.000
I95 Hypotension
0.755 0.245 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.752 0.248 0.000
I73.9 Peripheral vascular disease, unspecified
0.751 0.249 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.747 0.253 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.746 0.254 0.000
R42 Dizziness and giddiness
0.746 0.254 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.745 0.255 0.000
M81.9 Osteoporosis, unspecified
0.744 0.256 0.000
E87.7 Fluid overload
0.743 0.257 0.000
I77.1 Stricture of artery
0.743 0.257 0.000
S70-S79 Injuries to the hip and thigh
0.742 0.258 0.000
I46 Cardiac arrest
0.740 0.260 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.739 0.261 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.738 0.262 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.737 0.263 0.000
Chapter XXII Codes for special purposes
0.736 0.264 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.734 0.266 0.000
E83.4 Disorders of magnesium metabolism
0.733 0.267 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.732 0.268 0.000
M86-M90 Other osteopathies
0.732 0.268 0.000
S00-S09 Injuries to the head
0.732 0.268 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.731 0.269 0.000
J18 Pneumonia, organism unspecified
0.731 0.269 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.731 0.269 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.730 0.270 0.000
M20.2 Hallux rigidus
0.729 0.271 0.000
S40-S49 Injuries to the shoulder and upper arm
0.728 0.272 0.000
M21 Other acquired deformities of limbs
0.727 0.273 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.727 0.273 0.000
G62 Other polyneuropathies
0.726 0.274 0.000
M20.0 Deformity of finger(s)
0.726 0.274 0.000
M80 Osteoporosis with pathological fracture
0.725 0.275 0.000
O63.1 Prolonged second stage (of labour)
0.725 0.275 0.000
M22 Disorders of patella
0.724 0.276 0.000
O62.2 Other uterine inertia
0.723 0.277 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.723 0.277 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.722 0.278 0.000
I35 Nonrheumatic aortic valve disorders
0.722 0.278 0.000
E83.3 Disorders of phosphorus metabolism
0.721 0.279 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.720 0.280 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.720 0.280 0.000
I60 Subarachnoid haemorrhage
0.719 0.281 0.000
O80-O84 Delivery
0.719 0.281 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I62 Other nontraumatic intracranial haemorrhage
0.717 0.283 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.716 0.284 0.000
O85-O92 Complications predominantly related to the puerperium
0.715 0.285 0.000
S50-S59 Injuries to the elbow and forearm
0.715 0.285 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.714 0.286 0.000
M25.8 Other specified joint disorders
0.713 0.287 0.000
E40-E46 Malnutrition
0.713 0.287 0.000
O74 Complications of anaesthesia during labour and delivery
0.712 0.287 0.000
O73 Retained placenta and membranes, without haemorrhage
0.712 0.287 0.000
O71 Other obstetric trauma
0.712 0.287 0.000
O66 Other obstructed labour
0.712 0.287 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.712 0.287 0.000
O60 Preterm delivery
0.712 0.287 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.712 0.288 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.711 0.288 0.000
I20 Angina pectoris
0.712 0.288 0.000
I23 Certain current complications following acute myocardial infarction
0.711 0.289 0.000
B99-B99 Other infectious diseases
0.710 0.290 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.710 0.290 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.710 0.290 0.000
B50-B64 Protozoal diseases
0.710 0.290 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.710 0.290 0.000
B15-B19 Viral hepatitis
0.710 0.290 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.710 0.290 0.000
A80-A89 Viral infections of the central nervous system
0.710 0.290 0.000
A75-A79 Rickettsioses
0.710 0.290 0.000
A70-A74 Other diseases caused by chlamydiae
0.710 0.290 0.000
A65-A69 Other spirochaetal diseases
0.710 0.290 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.710 0.290 0.000
A20-A28 Certain zoonotic bacterial diseases
0.710 0.290 0.000
A15-A19 Tuberculosis
0.710 0.290 0.000
G70-G73 Diseases of myoneural junction and muscle
0.710 0.290 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.710 0.290 0.000
E87.0 Hyperosmolality and hypernatraemia
0.710 0.290 0.000
I45 Other conduction disorders
0.710 0.290 0.000
E11.9 Without complications
0.710 0.290 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.708 0.292 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.708 0.292 0.000
I78 Diseases of capillaries
0.708 0.292 0.000
I72 Other aneurysm
0.708 0.292 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.708 0.292 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.708 0.292 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.708 0.292 0.000
M91-M94 Chondropathies
0.708 0.292 0.000
M60-M63 Disorders of muscles
0.708 0.292 0.000
M00-M03 Infectious arthropathies
0.708 0.292 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.708 0.292 0.000
T79-T79 Certain early complications of trauma
0.707 0.293 0.000
J18.9 Pneumonia, unspecified
0.706 0.294 0.000
I52 Other heart disorders in diseases classified elsewhere
0.703 0.296 0.000
I48 Atrial fibrillation and flutter
0.703 0.296 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.703 0.296 0.000
I41 Myocarditis in diseases classified elsewhere
0.703 0.296 0.000
I40 Acute myocarditis
0.703 0.296 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.703 0.296 0.000
I37 Pulmonary valve disorders
0.703 0.296 0.000
I36 Nonrheumatic tricuspid valve disorders
0.703 0.296 0.000
I33 Acute and subacute endocarditis
0.703 0.296 0.000
I32 Pericarditis in diseases classified elsewhere
0.703 0.296 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.703 0.297 0.000
M34 Systemic sclerosis
0.703 0.297 0.000
M33 Dermatopolymyositis
0.703 0.297 0.000
M32 Systemic lupus erythematosus
0.703 0.297 0.000
M31 Other necrotising vasculopathies
0.703 0.297 0.000
M30 Polyarteritis nodosa and related conditions
0.703 0.297 0.000
E85 Amyloidosis
0.701 0.299 0.000
E84 Cystic fibrosis
0.701 0.299 0.000
E79 Disorders of purine and pyrimidine metabolism
0.701 0.299 0.000
E77 Disorders of glycoprotein metabolism
0.701 0.299 0.000
E76 Disorders of glycosaminoglycan metabolism
0.701 0.299 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.701 0.299 0.000
E74 Other disorders of carbohydrate metabolism
0.701 0.299 0.000
E73 Lactose intolerance
0.701 0.299 0.000
E72 Other disorders of amino-acid metabolism
0.701 0.299 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.701 0.299 0.000
E70 Disorders of aromatic amino-acid metabolism
0.701 0.299 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.701 0.299 0.000
M84 Disorders of continuity of bone
0.701 0.299 0.000
I05-I09 Chronic rheumatic heart diseases
0.701 0.299 0.000
T33-T35 Frostbite
0.700 0.300 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.700 0.300 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.700 0.300 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.700 0.300 0.000
T00-T07 Injuries involving multiple body regions
0.700 0.300 0.000
S10-S19 Injuries to the neck
0.700 0.300 0.000
E88 Other metabolic disorders
0.699 0.300 0.000
A07 Other protozoal intestinal diseases
0.699 0.301 0.000
A06 Amoebiasis
0.699 0.301 0.000
A05 Other bacterial foodborne intoxications
0.699 0.301 0.000
A03 Shigellosis
0.699 0.301 0.000
A02 Other Salmonella infections
0.699 0.301 0.000
A01 Typhoid and paratyphoid fevers
0.699 0.301 0.000
A00 Cholera
0.699 0.301 0.000
I25.6 Silent myocardial ischaemia
0.698 0.302 0.000
I25.5 Ischaemic cardiomyopathy
0.698 0.302 0.000
I25.4 Coronary artery aneurysm
0.698 0.302 0.000
I25.3 Aneurysm of heart
0.698 0.302 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.698 0.302 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.696 0.304 0.000
I44.7 Left bundle-branch block, unspecified
0.696 0.304 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.694 0.306 0.000
I42.9 Cardiomyopathy, unspecified
0.694 0.306 0.000
I31 Other diseases of pericardium
0.693 0.307 0.000
I70 Atherosclerosis
0.692 0.308 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.692 0.308 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.691 0.309 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.691 0.309 0.000
S80 Superficial injury of lower leg
0.691 0.309 0.000
I99 Other and unspecified disorders of circulatory system
0.691 0.309 0.000
M40-M43 Deforming dorsopathies
0.689 0.311 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.689 0.311 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.689 0.311 0.000
M24 Other specific joint derangements
0.689 0.311 0.000
A30-A49 Other bacterial diseases
0.688 0.312 0.000
S60-S69 Injuries to the wrist and hand
0.687 0.312 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.687 0.313 0.000
I95.1 Orthostatic hypotension
0.687 0.313 0.000
M25.7 Osteophyte
0.687 0.313 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.685 0.315 0.000
Chapter XX External causes of morbidity and mortality
0.684 0.316 0.000
J98 Other respiratory disorders
0.684 0.316 0.000
E83.5 Disorders of calcium metabolism
0.684 0.316 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.683 0.317 0.000
M20.4 Other hammer toe(s) (acquired)
0.683 0.317 0.000
O70.1 Second degree perineal laceration during delivery
0.683 0.317 0.000
Chapter V Mental and behavioural disorders
0.682 0.318 0.000
B80 Enterobiasis
0.681 0.319 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.680 0.320 0.000
M13 Other arthritis
0.680 0.320 0.000
M20.3 Other deformity of hallux (acquired)
0.679 0.321 0.000
I42.0 Dilated cardiomyopathy
0.679 0.321 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.678 0.322 0.000
G58 Other mononeuropathies
0.678 0.322 0.000
G54 Nerve root and plexus disorders
0.678 0.322 0.000
G52 Disorders of other cranial nerves
0.678 0.322 0.000
I44.0 Atrioventricular block, first degree
0.678 0.322 0.000
H04 Disorders of lachrymal system
0.677 0.323 0.000
J00 Acute nasopharyngitis [common cold]
0.676 0.324 0.000
T66-T78 Other and unspecified effects of external causes
0.675 0.325 0.000
M35.0 Sicca syndrome [Sjogren]
0.675 0.325 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.674 0.326 0.000
J43 Emphysema
0.674 0.326 0.000
I38 Endocarditis, valve unspecified
0.672 0.328 0.000
M07 Psoriatic and enteropathic arthropathies
0.672 0.328 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.671 0.329 0.000
M14 Arthropathies in other diseases classified elsewhere
0.670 0.330 0.000
M25.57 Pain in joint (Ankle and foot)
0.669 0.331 0.000
E22 Hyperfunction of pituitary gland
0.669 0.331 0.000
I74.5 Embolism and thrombosis of iliac artery
0.667 0.332 0.000
M25.51 Pain in joint (Shoulder region)
0.667 0.333 0.000
O61.0 Failed medical induction of labour
0.666 0.334 0.000
M65-M68 Disorders of synovium and tendon
0.666 0.334 0.000
I42.2 Other hypertrophic cardiomyopathy
0.665 0.335 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.665 0.335 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.664 0.336 0.000
J60-J70 Lung diseases due to external agents
0.664 0.336 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.664 0.336 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.664 0.336 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.664 0.336 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.664 0.336 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.663 0.337 0.000
I44.2 Atrioventricular block, complete
0.663 0.337 0.000
R45 Symptoms and signs involving emotional state
0.663 0.337 0.000
E87.2 Acidosis
0.662 0.338 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.661 0.339 0.000
E87.4 Mixed disorder of acid-base balance
0.661 0.339 0.000
E87.3 Alkalosis
0.661 0.339 0.000
S20 Superficial injury of thorax
0.660 0.340 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.658 0.341 0.000
H10-H13 Disorders of conjunctiva
0.658 0.342 0.000
I67.9 Cerebrovascular disease, unspecified
0.658 0.342 0.000
I25.2 Old myocardial infarction
0.658 0.342 0.000
M23.3 Other meniscus derangements
0.658 0.342 0.000
H02 Other disorders of eyelid
0.658 0.342 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.657 0.343 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.657 0.343 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.657 0.343 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.657 0.343 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.657 0.343 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.657 0.343 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.657 0.343 0.000
I71.0 Dissection of aorta [any part]
0.657 0.343 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.656 0.344 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.654 0.346 0.000
I61 Intracerebral haemorrhage
0.654 0.346 0.000
I24.1 Dressler's syndrome
0.653 0.347 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.652 0.348 0.000
M85 Other disorders of bone density and structure
0.652 0.348 0.000
M83 Adult osteomalacia
0.652 0.348 0.000
M82 Osteoporosis in diseases classified elsewhere
0.652 0.348 0.000
E66 Obesity
0.652 0.348 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.649 0.351 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.649 0.351 0.000
G53.0 Postzoster neuralgia
0.648 0.352 0.000
E11.5 With peripheral circulatory complications
0.647 0.353 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.647 0.353 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.645 0.355 0.000
O67.9 Intrapartum haemorrhage, unspecified
0.644 0.355 0.000
B35-B49 Mycoses
0.643 0.356 0.000
O63.0 Prolonged first stage (of labour)
0.642 0.358 0.000
G35 Multiple sclerosis
0.642 0.358 0.000
G83 Other paralytic syndromes
0.641 0.359 0.000
G82 Paraplegia and tetraplegia
0.641 0.359 0.000
G80 Infantile cerebral palsy
0.641 0.359 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.640 0.360 0.000
G62.9 Polyneuropathy, unspecified
0.639 0.361 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.639 0.361 0.000
O15 Eclampsia
0.639 0.361 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.639 0.361 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.639 0.361 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.639 0.361 0.000
G90-G99 Other disorders of the nervous system
0.638 0.362 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.638 0.362 0.000
G50 Disorders of trigeminal nerve
0.638 0.362 0.000
E29 Testicular dysfunction
0.638 0.362 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.638 0.362 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.637 0.363 0.000
M25.9 Joint disorder, unspecified
0.636 0.364 0.000
M25.3 Other instability of joint
0.636 0.364 0.000
M25.2 Flail joint
0.636 0.364 0.000
M25.1 Fistula of joint
0.636 0.364 0.000
M25.0 Haemarthrosis
0.636 0.364 0.000
M45-M49 Spondylopathies
0.636 0.364 0.000
T17 Foreign body in respiratory tract
0.635 0.365 0.000
E11.2 With renal complications
0.634 0.366 0.000
S22.4 Multiple fractures of ribs
0.632 0.368 0.000
B02 Zoster [herpes zoster]
0.632 0.368 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.632 0.368 0.000
O72.0 Third-stage haemorrhage
0.628 0.372 0.000
I77.6 Arteritis, unspecified
0.627 0.373 0.000
H50 Other strabismus
0.626 0.374 0.000
I77.8 Other specified disorders of arteries and arterioles
0.626 0.374 0.000
I77.5 Necrosis of artery
0.626 0.374 0.000
I77.4 Coeliac artery compression syndrome
0.626 0.374 0.000
I77.3 Arterial fibromuscular dysplasia
0.626 0.374 0.000
I77.2 Rupture of artery
0.626 0.374 0.000
I77.0 Arteriovenous fistula, acquired
0.626 0.374 0.000
I44.1 Atrioventricular block, second degree
0.625 0.375 0.000
I20.8 Other forms of angina pectoris
0.625 0.375 0.000
S27 Injury of other and unspecified intrathoracic organs
0.625 0.375 0.000
H55-H59 Other disorders of eye and adnexa
0.625 0.375 0.000
I63 Cerebral infarction
0.624 0.376 0.000
M25.53 Pain in joint (Forearm)
0.623 0.377 0.000
J02 Acute pharyngitis
0.622 0.378 0.000
I42.8 Other cardiomyopathies
0.622 0.378 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.622 0.378 0.000
I42.6 Alcoholic cardiomyopathy
0.622 0.378 0.000
I42.5 Other restrictive cardiomyopathy
0.622 0.378 0.000
I42.4 Endocardial fibroelastosis
0.622 0.378 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.622 0.378 0.000
E13 Other specified diabetes mellitus
0.621 0.378 0.000
E12 Malnutrition-related diabetes mellitus
0.621 0.378 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.620 0.379 0.000
E83.8 Other disorders of mineral metabolism
0.620 0.379 0.000
E83.2 Disorders of zinc metabolism
0.620 0.379 0.000
E83.0 Disorders of copper metabolism
0.620 0.379 0.000
T86 Failure and rejection of transplanted organs and tissues
0.620 0.380 0.000
I49 Other cardiac arrhythmias
0.620 0.380 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.620 0.380 0.000
I95.2 Hypotension due to drugs
0.619 0.381 0.000
E10 Insulin-dependent diabetes mellitus
0.618 0.382 0.000
H05 Disorders of orbit
0.616 0.383 0.000
H53-H54 Visual disturbances and blindness
0.615 0.385 0.000
J84 Other interstitial pulmonary diseases
0.615 0.385 0.000
G51 Facial nerve disorders
0.614 0.385 0.000
S29 Other and unspecified injuries of thorax
0.614 0.386 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.614 0.386 0.000
S26 Injury of heart
0.614 0.386 0.000
S25 Injury of blood vessels of thorax
0.614 0.386 0.000
S24 Injury of nerves and spinal cord at thorax level
0.614 0.386 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.614 0.386 0.000
S21 Open wound of thorax
0.614 0.386 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.614 0.386 0.000
I44.6 Other and unspecified fascicular block
0.614 0.386 0.000
I44.5 Left posterior fascicular block
0.614 0.386 0.000
I44.4 Left anterior fascicular block
0.614 0.386 0.000
I44.3 Other and unspecified atrioventricular block
0.614 0.386 0.000
I30.9 Acute pericarditis, unspecified
0.614 0.386 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.613 0.387 0.000
I74.8 Embolism and thrombosis of other arteries
0.613 0.387 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.613 0.387 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.613 0.387 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.613 0.387 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.613 0.387 0.000
B25-B34 Other viral diseases
0.611 0.389 0.000
E55 Vitamin D deficiency
0.611 0.389 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.610 0.390 0.000
G57.8 Other mononeuropathies of lower limb
0.610 0.390 0.000
G57.5 Tarsal tunnel syndrome
0.610 0.390 0.000
G57.4 Lesion of medial popliteal nerve
0.610 0.390 0.000
G57.3 Lesion of lateral popliteal nerve
0.610 0.390 0.000
G57.2 Lesion of femoral nerve
0.610 0.390 0.000
G57.1 Meralgia paraesthetica
0.610 0.390 0.000
G57.0 Lesion of sciatic nerve
0.610 0.390 0.000
O75.9 Complication of labour and delivery, unspecified
0.609 0.391 0.000
O75.8 Other specified complications of labour and delivery
0.609 0.391 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.609 0.391 0.000
O75.4 Other complications of obstetric surgery and procedures
0.609 0.391 0.000
O75.3 Other infection during labour
0.609 0.391 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.609 0.391 0.000
O75.1 Shock during or following labour and delivery
0.609 0.391 0.000
O75.0 Maternal distress during labour and delivery
0.609 0.391 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.608 0.392 0.000
G37 Other demyelinating diseases of central nervous system
0.608 0.392 0.000
O63.9 Long labour, unspecified
0.608 0.392 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.608 0.392 0.000
G61 Inflammatory polyneuropathy
0.608 0.392 0.000
G60 Hereditary and idiopathic neuropathy
0.608 0.392 0.000
G64 Other disorders of peripheral nervous system
0.608 0.392 0.000
S01 Open wound of head
0.607 0.393 0.000
I67.8 Other specified cerebrovascular diseases
0.607 0.393 0.000
E23 Hypofunction and other disorders of pituitary gland
0.607 0.393 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.607 0.393 0.000
G25 Other extrapyramidal and movement disorders
0.606 0.394 0.000
E87.6 Hypokalaemia
0.606 0.394 0.000
M35.3 Polymyalgia rheumatica
0.606 0.394 0.000
J03 Acute tonsillitis
0.606 0.394 0.000
J98.1 Pulmonary collapse
0.605 0.395 0.000
O42 Premature rupture of membranes
0.603 0.397 0.000
A08 Viral and other specified intestinal infections
0.602 0.397 0.000
B07 Viral warts
0.602 0.398 0.000
Q50-Q56 Congenital malformations of genital organs
0.601 0.399 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.600 0.400 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.600 0.400 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.600 0.400 0.000
O62.9 Abnormality of forces of labour, unspecified
0.599 0.400 0.000
O62.8 Other abnormalities of forces of labour
0.599 0.400 0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions
0.599 0.400 0.000
O62.3 Precipitate labour
0.599 0.400 0.000
O62.1 Secondary uterine inertia
0.599 0.400 0.000
O62.0 Primary inadequate contractions
0.599 0.400 0.000
M11 Other crystal arthropathies
0.599 0.400 0.000
M05 Seropositive rheumatoid arthritis
0.599 0.401 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.598 0.402 0.000
G56.8 Other mononeuropathies of upper limb
0.598 0.402 0.000
G56.4 Causalgia
0.598 0.402 0.000
G56.3 Lesion of radial nerve
0.598 0.402 0.000
G56.1 Other lesions of median nerve
0.598 0.402 0.000
E11.4 With neurological complications
0.598 0.402 0.000
Q60-Q64 Congenital malformations of the urinary system
0.596 0.404 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.596 0.404 0.000
O97 Death from sequelae of direct obstetric causes
0.596 0.404 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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