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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs79990645
log Bayes Factor = 16.7731
Chromosome 1   position 42,924,003  (GRCh37) Explore rs79990645 on Ensembl!
Variant rs79990645 is part of Cluster X0049

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
K55-K64 Other diseases of intestines
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.998 0.002 0.000
E70-E90 Metabolic disorders
0.997 0.003 0.000
Chapter XIV Diseases of the genitourinary system
0.996 0.004 0.000
Chapter VII Diseases of the eye and adnexa
0.989 0.011 0.000
E10-E14 Diabetes mellitus
0.988 0.012 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.983 0.017 0.000
M20-M25 Other joint disorders
0.974 0.026 0.000
I25 Chronic ischaemic heart disease
0.971 0.029 0.000
N17-N19 Renal failure
0.971 0.029 0.000
M25 Other joint disorders, not elsewhere classified
0.968 0.032 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.966 0.034 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.966 0.034 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.965 0.035 0.000
E10 Insulin-dependent diabetes mellitus
0.964 0.036 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.963 0.037 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.962 0.038 0.000
K59 Other functional intestinal disorders
0.955 0.045 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.947 0.053 0.000
K60 Fissure and fistula of anal and rectal regions
0.946 0.054 0.000
K22 Other diseases of oesophagus
0.944 0.056 0.000
I20 Angina pectoris
0.944 0.056 0.000
N18 Chronic renal failure
0.943 0.057 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.942 0.058 0.000
M25.5 Pain in joint
0.940 0.060 0.000
N18.9 Chronic renal failure, unspecified
0.933 0.067 0.000
I30-I52 Other forms of heart disease
0.927 0.073 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.926 0.074 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.925 0.075 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.925 0.075 0.000
K59.0 Constipation
0.924 0.076 0.000
E10.9 Without complications
0.923 0.077 0.000
M50-M54 Other dorsopathies
0.923 0.077 0.000
K55 Vascular disorders of intestine
0.918 0.082 0.000
H00 Hordeolum and chalazion
0.918 0.082 0.000
K60.3 Anal fistula
0.917 0.083 0.000
K70-K77 Diseases of liver
0.916 0.084 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.915 0.085 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.915 0.085 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.915 0.085 0.000
Chapter I Certain infectious and parasitic diseases
0.914 0.086 0.000
R04 Haemorrhage from respiratory passages
0.912 0.088 0.000
R94 Abnormal results of function studies
0.910 0.090 0.000
E14 Unspecified diabetes mellitus
0.909 0.091 0.000
E87.7 Fluid overload
0.906 0.094 0.000
R02 Gangrene, not elsewhere classified
0.905 0.095 0.000
I35 Nonrheumatic aortic valve disorders
0.903 0.097 0.000
I24 Other acute ischaemic heart diseases
0.903 0.097 0.000
I71 Aortic aneurysm and dissection
0.895 0.105 0.000
I20.0 Unstable angina
0.891 0.109 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.888 0.112 0.000
K21 Gastro-oesophageal reflux disease
0.885 0.115 0.000
R04.0 Epistaxis
0.883 0.117 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.880 0.120 0.000
K22.1 Ulcer of oesophagus
0.878 0.122 0.000
I21 Acute myocardial infarction
0.876 0.124 0.000
H00.1 Chalazion
0.875 0.125 0.000
R94.5 Abnormal results of liver function studies
0.874 0.126 0.000
K63 Other diseases of intestine
0.872 0.128 0.000
I73 Other peripheral vascular diseases
0.864 0.136 0.000
N95 Menopausal and other perimenopausal disorders
0.858 0.142 0.000
M45-M49 Spondylopathies
0.858 0.142 0.000
M25.7 Osteophyte
0.854 0.146 0.000
M05-M14 Inflammatory polyarthropathies
0.854 0.146 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.853 0.147 0.000
K58 Irritable bowel syndrome
0.851 0.149 0.000
E78.0 Pure hypercholesterolaemia
0.848 0.152 0.000
E20-E35 Disorders of other endocrine glands
0.848 0.152 0.000
N60-N64 Disorders of breast
0.846 0.154 0.000
H53-H54 Visual disturbances and blindness
0.845 0.155 0.000
K62 Other diseases of anus and rectum
0.842 0.158 0.000
M25.51 Pain in joint (Shoulder region)
0.841 0.159 0.000
I21.9 Acute myocardial infarction, unspecified
0.841 0.159 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.840 0.160 0.000
N17 Acute renal failure
0.840 0.160 0.000
Chapter II Neoplasms
0.840 0.160 0.000
N81 Female genital prolapse
0.840 0.160 0.000
A00-A09 Intestinal infectious diseases
0.839 0.161 0.000
M25.56 Pain in joint (Lower leg)
0.839 0.161 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.838 0.162 0.000
E14.9 Without complications
0.838 0.162 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.837 0.163 0.000
K20 Oesophagitis
0.837 0.163 0.000
M51 Other intervertebral disk disorders
0.836 0.164 0.000
E83 Disorders of mineral metabolism
0.832 0.168 0.000
I25.1 Atherosclerotic heart disease
0.830 0.170 0.000
I49 Other cardiac arrhythmias
0.828 0.171 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.826 0.174 0.000
L40-L45 Papulosquamous disorders
0.823 0.177 0.000
N72 Inflammatory disease of cervix uteri
0.823 0.177 0.000
H02 Other disorders of eyelid
0.820 0.180 0.000
R09.1 Pleurisy
0.820 0.180 0.000
K55.0 Acute vascular disorders of intestine
0.819 0.181 0.000
Chapter XXI Factors influencing health status and contact with health services
0.815 0.185 0.000
K62.5 Haemorrhage of anus and rectum
0.815 0.185 0.000
K22.4 Dyskinesia of oesophagus
0.815 0.185 0.000
E78.5 Hyperlipidaemia, unspecified
0.814 0.186 0.000
M54 Dorsalgia
0.811 0.189 0.000
D50-D53 Nutritional anaemias
0.810 0.190 0.000
K12 Stomatitis and related lesions
0.809 0.191 0.000
H30-H36 Disorders of choroid and retina
0.808 0.192 0.000
N25-N29 Other disorders of kidney and ureter
0.808 0.192 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.807 0.193 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.807 0.193 0.000
K76 Other diseases of liver
0.806 0.194 0.000
M24 Other specific joint derangements
0.806 0.194 0.000
E50-E64 Other nutritional deficiencies
0.806 0.194 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.804 0.196 0.000
N81.1 Cystocele
0.803 0.197 0.000
M25.8 Other specified joint disorders
0.801 0.199 0.000
I35.1 Aortic (valve) insufficiency
0.799 0.201 0.000
R03.1 Nonspecific low blood-pressure reading
0.799 0.201 0.000
K08 Other disorders of teeth and supporting structures
0.798 0.202 0.000
E88 Other metabolic disorders
0.798 0.202 0.000
N10-N16 Renal tubulo-interstitial diseases
0.797 0.202 0.000
M40-M43 Deforming dorsopathies
0.797 0.203 0.000
I77 Other disorders of arteries and arterioles
0.797 0.203 0.000
I60-I69 Cerebrovascular diseases
0.797 0.203 0.000
R47-R49 Symptoms and signs involving speech and voice
0.794 0.206 0.000
I31 Other diseases of pericardium
0.794 0.206 0.000
E10.4 With neurological complications
0.793 0.207 0.000
R01 Cardiac murmurs and other cardiac sounds
0.791 0.209 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.790 0.210 0.000
Chapter VIII Diseases of the ear and mastoid process
0.790 0.210 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.788 0.212 0.000
N95.2 Postmenopausal atrophic vaginitis
0.786 0.214 0.000
I24.8 Other forms of acute ischaemic heart disease
0.785 0.215 0.000
Chapter XXII Codes for special purposes
0.785 0.215 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.781 0.219 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.780 0.220 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.778 0.222 0.000
L20-L30 Dermatitis and eczema
0.778 0.222 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.778 0.222 0.000
M25.57 Pain in joint (Ankle and foot)
0.777 0.223 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.776 0.224 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.775 0.225 0.000
K22.8 Other specified diseases of oesophagus
0.775 0.225 0.000
E87.0 Hyperosmolality and hypernatraemia
0.773 0.227 0.000
M25.3 Other instability of joint
0.773 0.227 0.000
M91-M94 Chondropathies
0.771 0.229 0.000
M25.76 Osteophyte (Lower leg)
0.771 0.229 0.000
E10.3 With ophthalmic complications
0.769 0.231 0.000
N87 Dysplasia of cervix uteri
0.767 0.233 0.000
E40-E46 Malnutrition
0.767 0.233 0.000
H55-H59 Other disorders of eye and adnexa
0.767 0.233 0.000
K55.2 Angiodysplasia of colon
0.766 0.234 0.000
E00-E07 Disorders of thyroid gland
0.766 0.234 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.765 0.235 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.764 0.236 0.000
N99-N99 Other disorders of the genitourinary system
0.764 0.236 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.760 0.240 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.759 0.241 0.000
M51.2 Other specified intervertebral disk displacement
0.758 0.242 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.758 0.242 0.000
M80-M85 Disorders of bone density and structure
0.756 0.243 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.756 0.244 0.000
R20 Disturbances of skin sensation
0.756 0.244 0.000
B35-B49 Mycoses
0.755 0.245 0.000
D00-D09 In situ neoplasms
0.755 0.245 0.000
H54 Blindness and low vision
0.755 0.245 0.000
H40-H42 Glaucoma
0.754 0.246 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.753 0.247 0.000
Chapter V Mental and behavioural disorders
0.753 0.247 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.753 0.247 0.000
L40 Psoriasis
0.753 0.247 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.752 0.248 0.000
L50-L54 Urticaria and erythema
0.750 0.250 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.749 0.251 0.000
Z50 Care involving use of rehabilitation procedures
0.749 0.251 0.000
N92 Excessive, frequent and irregular menstruation
0.748 0.252 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.747 0.253 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.747 0.253 0.000
N17.9 Acute renal failure, unspecified
0.746 0.254 0.000
I35.8 Other aortic valve disorders
0.742 0.258 0.000
I73.9 Peripheral vascular disease, unspecified
0.742 0.258 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.742 0.258 0.000
K22.7 Barrett's oesophagus
0.741 0.259 0.000
K25 Gastric ulcer
0.740 0.260 0.000
N30-N39 Other diseases of urinary system
0.738 0.262 0.000
I33 Acute and subacute endocarditis
0.737 0.263 0.000
K63.5 Polyp of colon
0.736 0.264 0.000
H02.8 Other specified disorders of eyelid
0.735 0.265 0.000
I35.0 Aortic (valve) stenosis
0.735 0.265 0.000
M86-M90 Other osteopathies
0.735 0.265 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.734 0.266 0.000
H01 Other inflammation of eyelid
0.733 0.267 0.000
K63.8 Other specified diseases of intestine
0.732 0.268 0.000
R09.2 Respiratory arrest
0.732 0.268 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.731 0.269 0.000
A08 Viral and other specified intestinal infections
0.731 0.269 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.731 0.269 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.730 0.270 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.728 0.272 0.000
M48 Other spondylopathies
0.728 0.272 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.727 0.273 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.727 0.273 0.000
K61 Abscess of anal and rectal regions
0.726 0.274 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.726 0.274 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.726 0.274 0.000
D50 Iron deficiency anaemia
0.723 0.277 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.723 0.277 0.000
K70 Alcoholic liver disease
0.722 0.278 0.000
E83.1 Disorders of iron metabolism
0.722 0.278 0.000
I20.8 Other forms of angina pectoris
0.721 0.278 0.000
I25.2 Old myocardial infarction
0.721 0.279 0.000
I22 Subsequent myocardial infarction
0.721 0.279 0.000
K22.9 Disease of oesophagus, unspecified
0.720 0.280 0.000
N60 Benign mammary dysplasia
0.720 0.280 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.719 0.281 0.000
E87.2 Acidosis
0.718 0.281 0.000
I73.0 Raynaud's syndrome
0.718 0.282 0.000
A30-A49 Other bacterial diseases
0.717 0.282 0.000
H10-H13 Disorders of conjunctiva
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I25.5 Ischaemic cardiomyopathy
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.716 0.284 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
E87.5 Hyperkalaemia
0.715 0.285 0.000
E85 Amyloidosis
0.715 0.285 0.000
E84 Cystic fibrosis
0.715 0.285 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.715 0.285 0.000
E79 Disorders of purine and pyrimidine metabolism
0.715 0.285 0.000
E77 Disorders of glycoprotein metabolism
0.715 0.285 0.000
E76 Disorders of glycosaminoglycan metabolism
0.715 0.285 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.715 0.285 0.000
E74 Other disorders of carbohydrate metabolism
0.715 0.285 0.000
E73 Lactose intolerance
0.715 0.285 0.000
E72 Other disorders of amino-acid metabolism
0.715 0.285 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.715 0.285 0.000
E70 Disorders of aromatic amino-acid metabolism
0.715 0.285 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.715 0.285 0.000
K76.9 Liver disease, unspecified
0.713 0.286 0.000
N89 Other noninflammatory disorders of vagina
0.712 0.288 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.712 0.288 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.709 0.291 0.000
M46 Other inflammatory spondylopathies
0.709 0.291 0.000
E13 Other specified diabetes mellitus
0.708 0.291 0.000
E12 Malnutrition-related diabetes mellitus
0.708 0.291 0.000
E86 Volume depletion
0.708 0.292 0.000
S40-S49 Injuries to the shoulder and upper arm
0.708 0.292 0.000
M21 Other acquired deformities of limbs
0.708 0.292 0.000
D70 Agranulocytosis
0.707 0.293 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.707 0.293 0.000
I70 Atherosclerosis
0.707 0.293 0.000
M54.5 Low back pain
0.707 0.293 0.000
K13 Other diseases of lip and oral mucosa
0.704 0.296 0.000
Z95.0 Presence of cardiac pacemaker
0.704 0.296 0.000
E14.3 With ophthalmic complications
0.703 0.297 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.703 0.297 0.000
L40.5 Arthropathic psoriasis
0.703 0.297 0.000
K14 Diseases of tongue
0.701 0.299 0.000
I20.1 Angina pectoris with documented spasm
0.701 0.299 0.000
I35.9 Aortic valve disorder, unspecified
0.701 0.299 0.000
K60.1 Chronic anal fissure
0.701 0.299 0.000
N18.0 End-stage renal disease
0.699 0.301 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.699 0.301 0.000
M34 Systemic sclerosis
0.699 0.301 0.000
M33 Dermatopolymyositis
0.699 0.301 0.000
M32 Systemic lupus erythematosus
0.699 0.301 0.000
M30 Polyarteritis nodosa and related conditions
0.699 0.301 0.000
E22 Hyperfunction of pituitary gland
0.698 0.302 0.000
Z85 Personal history of malignant neoplasm
0.698 0.302 0.000
E10.1 With ketoacidosis
0.697 0.303 0.000
H04 Disorders of lachrymal system
0.697 0.303 0.000
I25.6 Silent myocardial ischaemia
0.696 0.303 0.000
I25.4 Coronary artery aneurysm
0.696 0.303 0.000
I25.3 Aneurysm of heart
0.696 0.303 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.696 0.303 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.696 0.304 0.000
N97 Female infertility
0.695 0.305 0.000
N81.4 Uterovaginal prolapse, unspecified
0.695 0.305 0.000
M25.9 Joint disorder, unspecified
0.694 0.306 0.000
M25.2 Flail joint
0.694 0.306 0.000
M25.1 Fistula of joint
0.694 0.306 0.000
M25.0 Haemarthrosis
0.694 0.306 0.000
K27 Peptic ulcer, site unspecified
0.694 0.306 0.000
E65-E68 Obesity and other hyperalimentation
0.694 0.306 0.000
K75 Other inflammatory liver diseases
0.693 0.307 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.693 0.307 0.000
E87.4 Mixed disorder of acid-base balance
0.693 0.307 0.000
E87.3 Alkalosis
0.693 0.307 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.692 0.307 0.000
I72 Other aneurysm
0.692 0.307 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.692 0.308 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.692 0.308 0.000
K02 Dental caries
0.691 0.309 0.000
E10.8 With unspecified complications
0.691 0.309 0.000
E10.7 With multiple complications
0.691 0.309 0.000
E10.6 With other specified complications
0.691 0.309 0.000
E10.5 With peripheral circulatory complications
0.691 0.309 0.000
E10.2 With renal complications
0.691 0.309 0.000
E10.0 With coma
0.691 0.309 0.000
K28 Gastrojejunal ulcer
0.691 0.309 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.691 0.309 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.690 0.310 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.690 0.310 0.000
H05 Disorders of orbit
0.690 0.310 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.690 0.310 0.000
M06 Other rheumatoid arthritis
0.690 0.310 0.000
M11 Other crystal arthropathies
0.689 0.311 0.000
H43-H45 Disorders of vitreous body and globe
0.689 0.311 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.689 0.311 0.000
K26 Duodenal ulcer
0.689 0.311 0.000
I31.3 Pericardial effusion (noninflammatory)
0.686 0.313 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.686 0.314 0.000
K65-K67 Diseases of peritoneum
0.686 0.314 0.000
M70-M79 Other soft tissue disorders
0.686 0.314 0.000
M24.1 Other articular cartilage disorders
0.685 0.315 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.685 0.315 0.000
H65-H75 Diseases of middle ear and mastoid
0.685 0.315 0.000
K59.9 Functional intestinal disorder, unspecified
0.684 0.315 0.000
K59.8 Other specified functional intestinal disorders
0.684 0.315 0.000
K59.4 Anal spasm
0.684 0.315 0.000
K59.3 Megacolon, not elsewhere classified
0.684 0.315 0.000
K59.2 Neurogenic bowel, not elsewhere classified
0.684 0.315 0.000
K59.1 Functional diarrhoea
0.684 0.315 0.000
I20.9 Angina pectoris, unspecified
0.683 0.317 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.682 0.318 0.000
D60-D64 Aplastic and other anaemias
0.682 0.318 0.000
I95 Hypotension
0.682 0.318 0.000
M25.84 Other specified joint disorders (Hand)
0.682 0.318 0.000
H33 Retinal detachments and breaks
0.680 0.320 0.000
E78.8 Other disorders of lipoprotein metabolism
0.679 0.321 0.000
E78.6 Lipoprotein deficiency
0.679 0.321 0.000
E78.4 Other hyperlipidaemia
0.679 0.321 0.000
E78.3 Hyperchylomicronaemia
0.679 0.321 0.000
E78.2 Mixed hyperlipidaemia
0.679 0.321 0.000
E78.1 Pure hyperglyceridaemia
0.679 0.321 0.000
K72 Hepatic failure, not elsewhere classified
0.679 0.321 0.000
K60.5 Anorectal fistula
0.679 0.321 0.000
K60.4 Rectal fistula
0.679 0.321 0.000
K60.0 Acute anal fissure
0.679 0.321 0.000
M25.54 Pain in joint (Hand)
0.678 0.322 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.677 0.323 0.000
K22.5 Diverticulum of oesophagus, acquired
0.677 0.323 0.000
K22.3 Perforation of oesophagus
0.677 0.323 0.000
K22.0 Achalasia of cardia
0.677 0.323 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.676 0.324 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.676 0.324 0.000
N18.8 Other chronic renal failure
0.676 0.324 0.000
N18.2 Chronic kidney disease, stage 2
0.676 0.324 0.000
N18.1 Chronic kidney disease, stage 1
0.676 0.324 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.676 0.324 0.000
D55-D59 Haemolytic anaemias
0.675 0.325 0.000
M25.59 Pain in joint (Site unspecified)
0.674 0.326 0.000
M25.58 Pain in joint (Other)
0.674 0.326 0.000
M25.53 Pain in joint (Forearm)
0.674 0.326 0.000
M25.52 Pain in joint (Upper arm)
0.674 0.326 0.000
R42 Dizziness and giddiness
0.673 0.327 0.000
K74 Fibrosis and cirrhosis of liver
0.673 0.327 0.000
K12.1 Other forms of stomatitis
0.671 0.329 0.000
D50.8 Other iron deficiency anaemias
0.671 0.329 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.670 0.329 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.670 0.330 0.000
N18.4 Chronic kidney disease, stage 4
0.670 0.330 0.000
R45 Symptoms and signs involving emotional state
0.669 0.331 0.000
Z95.1 Presence of aortocoronary bypass graft
0.668 0.332 0.000
M20 Acquired deformities of fingers and toes
0.668 0.332 0.000
N26 Unspecified contracted kidney
0.668 0.332 0.000
D75 Other diseases of blood and blood-forming organs
0.667 0.332 0.000
K07 Dentofacial anomalies [including malocclusion]
0.667 0.333 0.000
K05 Gingivitis and periodontal diseases
0.667 0.333 0.000
I44 Atrioventricular and left bundle-branch block
0.666 0.334 0.000
N00-N08 Glomerular diseases
0.666 0.334 0.000
M22 Disorders of patella
0.665 0.335 0.000
H02.9 Disorder of eyelid, unspecified
0.665 0.335 0.000
D73 Diseases of spleen
0.665 0.335 0.000
B15-B19 Viral hepatitis
0.665 0.335 0.000
I52 Other heart disorders in diseases classified elsewhere
0.664 0.335 0.000
I48 Atrial fibrillation and flutter
0.664 0.335 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.664 0.335 0.000
I41 Myocarditis in diseases classified elsewhere
0.664 0.335 0.000
I40 Acute myocarditis
0.664 0.335 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.664 0.335 0.000
I37 Pulmonary valve disorders
0.664 0.335 0.000
I36 Nonrheumatic tricuspid valve disorders
0.664 0.335 0.000
I32 Pericarditis in diseases classified elsewhere
0.664 0.335 0.000
I30 Acute pericarditis
0.664 0.335 0.000
D05 Carcinoma in situ of breast
0.664 0.336 0.000
N86 Erosion and ectropion of cervix uteri
0.664 0.336 0.000
K04 Diseases of pulp and periapical tissues
0.664 0.336 0.000
Chapter XX External causes of morbidity and mortality
0.664 0.336 0.000
L10-L14 Bullous disorders
0.664 0.336 0.000
K10 Other diseases of jaws
0.663 0.336 0.000
K09 Cysts of oral region, not elsewhere classified
0.663 0.336 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.663 0.336 0.000
K03 Other diseases of hard tissues of teeth
0.663 0.336 0.000
K00 Disorders of tooth development and eruption
0.663 0.336 0.000
M31 Other necrotising vasculopathies
0.663 0.337 0.000
N98 Complications associated with artificial fertilisation
0.663 0.337 0.000
N91 Absent, scanty and rare menstruation
0.663 0.337 0.000
N82 Fistulae involving female genital tract
0.663 0.337 0.000
N96 Habitual aborter
0.663 0.337 0.000
N81.3 Complete uterovaginal prolapse
0.663 0.337 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.663 0.337 0.000
K22.2 Oesophageal obstruction
0.662 0.338 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.662 0.338 0.000
M53 Other dorsopathies, not elsewhere classified
0.662 0.338 0.000
D80-D89 Certain disorders involving the immune mechanism
0.661 0.339 0.000
Z95.4 Presence of other heart-valve replacement
0.661 0.339 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.661 0.339 0.000
I49.5 Sick sinus syndrome
0.660 0.340 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.659 0.341 0.000
K55.9 Vascular disorder of intestine, unspecified
0.658 0.342 0.000
K55.8 Other vascular disorders of intestine
0.658 0.342 0.000
K55.1 Chronic vascular disorders of intestine
0.658 0.342 0.000
L60-L75 Disorders of skin appendages
0.658 0.342 0.000
M25.50 Pain in joint (Multiple sites)
0.658 0.342 0.000
K11 Diseases of salivary glands
0.657 0.343 0.000
K77 Liver disorders in diseases classified elsewhere
0.657 0.343 0.000
K73 Chronic hepatitis, not elsewhere classified
0.657 0.343 0.000
K71 Toxic liver disease
0.657 0.343 0.000
R09.3 Abnormal sputum
0.656 0.344 0.000
R09.0 Asphyxia
0.656 0.344 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.656 0.344 0.000
B99-B99 Other infectious diseases
0.655 0.345 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.655 0.345 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.655 0.345 0.000
B65-B83 Helminthiases
0.655 0.345 0.000
B50-B64 Protozoal diseases
0.655 0.345 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.655 0.345 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.655 0.345 0.000
A80-A89 Viral infections of the central nervous system
0.655 0.345 0.000
A75-A79 Rickettsioses
0.655 0.345 0.000
A70-A74 Other diseases caused by chlamydiae
0.655 0.345 0.000
A65-A69 Other spirochaetal diseases
0.655 0.345 0.000
A20-A28 Certain zoonotic bacterial diseases
0.655 0.345 0.000
A15-A19 Tuberculosis
0.655 0.345 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.654 0.345 0.000
R47 Speech disturbances, not elsewhere classified
0.654 0.346 0.000
C64-C68 Malignant neoplasms of urinary tract
0.654 0.346 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.654 0.346 0.000
R04.9 Haemorrhage from respiratory passages, unspecified
0.654 0.346 0.000
R04.8 Haemorrhage from other sites in respiratory passages
0.654 0.346 0.000
R04.1 Haemorrhage from throat
0.654 0.346 0.000
M54.56 Low back pain (Lumbar region)
0.654 0.346 0.000
M65-M68 Disorders of synovium and tendon
0.654 0.346 0.000
R01.1 Cardiac murmur, unspecified
0.654 0.346 0.000
N30 Cystitis
0.653 0.346 0.000
R94.8 Abnormal results of function studies of other organs and systems
0.652 0.347 0.000
R94.7 Abnormal results of other endocrine function studies
0.652 0.347 0.000
R94.6 Abnormal results of thyroid function studies
0.652 0.347 0.000
R94.4 Abnormal results of kidney function studies
0.652 0.347 0.000
R94.2 Abnormal results of pulmonary function studies
0.652 0.347 0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses
0.652 0.347 0.000
R94.0 Abnormal results of function studies of central nervous system
0.652 0.347 0.000
E14.8 With unspecified complications
0.652 0.348 0.000
E14.7 With multiple complications
0.652 0.348 0.000
E14.6 With other specified complications
0.652 0.348 0.000
E14.5 With peripheral circulatory complications
0.652 0.348 0.000
E14.4 With neurological complications
0.652 0.348 0.000
E14.2 Withrenal complications
0.652 0.348 0.000
E14.1 With ketoacidosis
0.652 0.348 0.000
E14.0 With coma
0.652 0.348 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.652 0.348 0.000
M07 Psoriatic and enteropathic arthropathies
0.651 0.349 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.651 0.349 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.650 0.350 0.000
E11 Non-insulin-dependent diabetes mellitus
0.649 0.351 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.649 0.351 0.000
I49.3 Ventricular premature depolarisation
0.649 0.351 0.000
I49.9 Cardiac arrhythmia, unspecified
0.649 0.351 0.000
N70 Salpingitis and oophoritis
0.648 0.352 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.647 0.352 0.000
E53 Deficiency of other B group vitamins
0.647 0.353 0.000
M05 Seropositive rheumatoid arthritis
0.647 0.353 0.000
I24.1 Dressler's syndrome
0.647 0.353 0.000
I51 Complications and ill-defined descriptions of heart disease
0.646 0.354 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.646 0.354 0.000
M54.3 Sciatica
0.644 0.356 0.000
H36 Retinal disorders in diseases classified elsewhere
0.642 0.358 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.642 0.358 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.642 0.358 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.642 0.358 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.642 0.358 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.642 0.358 0.000
I71.0 Dissection of aorta [any part]
0.642 0.358 0.000
I38 Endocarditis, valve unspecified
0.641 0.358 0.000
Z50.5 Speech therapy
0.641 0.359 0.000
I77.6 Arteritis, unspecified
0.641 0.359 0.000
K63.9 Disease of intestine, unspecified
0.638 0.361 0.000
C43 Malignant melanoma of skin
0.638 0.361 0.000
L89 Decubitus ulcer
0.638 0.362 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.636 0.363 0.000
N76 Other inflammation of vagina and vulva
0.636 0.363 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.636 0.363 0.000
N71 Inflammatory disease of uterus, except cervix
0.636 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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