TreeWAS – Variant ID: rs799979

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.999	0.001
Chapter IX Diseases of the circulatory system	0.999	0.001
R50-R69 General symptoms and signs	0.998	0.002
Chapter XX External causes of morbidity and mortality	0.996	0.004
Chapter XI Diseases of the digestive system	0.991	0.009
R55 Syncope and collapse	0.990	0.010
K50-K52 Noninfective enteritis and colitis	0.968	0.032
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.959	0.041
Chapter I Certain infectious and parasitic diseases	0.954	0.046
I30-I52 Other forms of heart disease	0.953	0.047
K50 Crohn's disease [regional enteritis]	0.945	0.055
I70-I79 Diseases of arteries, arterioles and capillaries	0.944	0.056
I60-I69 Cerebrovascular diseases	0.944	0.056
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.935	0.065
K70-K77 Diseases of liver	0.932	0.068
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.916	0.084
R69 Unknown and unspecified causes of morbidity	0.910	0.090
R53 Malaise and fatigue	0.907	0.093
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.906	0.094
R52 Pain, not elsewhere classified	0.899	0.101
K50.9 Crohn's disease, unspecified	0.899	0.101
B95-B98 Bacterial, viral and other infectious agents	0.897	0.103
I95-I99 Other and unspecified disorders of the circulatory system	0.894	0.106
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.893	0.107
I34 Nonrheumatic mitral valve disorders	0.893	0.107
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.892	0.108
T36-T50 Poisoning by drugs, medicaments and biological substances	0.886	0.114
K40-K46 Hernia	0.886	0.114
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.882	0.118
S70-S79 Injuries to the hip and thigh	0.875	0.125
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.874	0.126
Chapter VI Diseases of the nervous system	0.872	0.128
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.871	0.129
S80-S89 Injuries to the knee and lower leg	0.863	0.137
I20-I25 Ischaemic heart diseases	0.861	0.139
Chapter XIV Diseases of the genitourinary system	0.859	0.141
R93 Abnormal findings on diagnostic imaging of other body structures	0.857	0.143
I67 Other cerebrovascular diseases	0.856	0.144
I63 Cerebral infarction	0.852	0.148
S50-S59 Injuries to the elbow and forearm	0.849	0.151
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.847	0.153
R52.1 Chronic intractable pain	0.844	0.156
K76 Other diseases of liver	0.843	0.157
K43 Ventral hernia	0.843	0.157
R94 Abnormal results of function studies	0.841	0.159
T66-T78 Other and unspecified effects of external causes	0.838	0.162
K51 Ulcerative colitis	0.833	0.167
K65-K67 Diseases of peritoneum	0.828	0.172
M05-M14 Inflammatory polyarthropathies	0.828	0.172
I73 Other peripheral vascular diseases	0.826	0.174
R73 Elevated blood glucose level	0.824	0.175
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.824	0.176
Y42.7 Androgens and anabolic congeners	0.824	0.176
W20-W49 Exposure to inanimate mechanical forces	0.821	0.179
X20-X29 Contact with venomous animals and plants	0.819	0.181
S90-S99 Injuries to the ankle and foot	0.818	0.182
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.816	0.184
I34.0 Mitral (valve) insufficiency	0.816	0.184
Chapter II Neoplasms	0.815	0.185
K43.9 Ventral hernia without obstruction or gangrene	0.812	0.188
R61 Hyperhidrosis	0.808	0.192
K50.0 Crohn's disease of small intestine	0.804	0.196
I63.9 Cerebral infarction, unspecified	0.799	0.201
S60-S69 Injuries to the wrist and hand	0.798	0.202
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.795	0.205
I42 Cardiomyopathy	0.793	0.207
N80-N98 Noninflammatory disorders of female genital tract	0.793	0.207
M06 Other rheumatoid arthritis	0.792	0.208
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.786	0.214
I67.9 Cerebrovascular disease, unspecified	0.786	0.214
I45 Other conduction disorders	0.786	0.214
I99 Other and unspecified disorders of circulatory system	0.785	0.215
V10-V19 Pedal cyclist injured in transport accident	0.781	0.219
I74 Arterial embolism and thrombosis	0.778	0.222
K76.0 Fatty (change of) liver, not elsewhere classified	0.778	0.222
T51 Toxic effect of alcohol	0.777	0.223
I25 Chronic ischaemic heart disease	0.777	0.223
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.775	0.225
K50.1 Crohn's disease of large intestine	0.773	0.227
T63 Toxic effect of contact with venomous animals	0.772	0.228
R42 Dizziness and giddiness	0.771	0.229
I31 Other diseases of pericardium	0.769	0.231
A30-A49 Other bacterial diseases	0.768	0.232
A00-A09 Intestinal infectious diseases	0.768	0.232
K72 Hepatic failure, not elsewhere classified	0.768	0.232
M06.9 Rheumatoid arthritis, unspecified	0.767	0.233
Y52 Agents primarily affecting the cardiovascular system	0.767	0.233
X60-X84 Intentional self-harm	0.763	0.237
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.762	0.238
S20-S29 Injuries to the thorax	0.761	0.239
R63 Symptoms and signs concerning food and fluid intake	0.760	0.239
S82 Fracture of lower leg, including ankle	0.760	0.239
S72 Fracture of femur	0.758	0.242
R94.5 Abnormal results of liver function studies	0.757	0.243
I73.9 Peripheral vascular disease, unspecified	0.757	0.243
Y40 Systemic antibiotics	0.754	0.246
G50-G59 Nerve, nerve root and plexus disorders	0.753	0.247
I34.1 Mitral (valve) prolapse	0.751	0.249
I33 Acute and subacute endocarditis	0.750	0.250
I25.8 Other forms of chronic ischaemic heart disease	0.750	0.250
Chapter XV Pregnancy, childbirth and the puerperium	0.749	0.251
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.749	0.251
W00-W19 Falls	0.749	0.251
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.748	0.252
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.746	0.254
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.746	0.254
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.745	0.255
S40-S49 Injuries to the shoulder and upper arm	0.743	0.257
I70 Atherosclerosis	0.741	0.259
I60 Subarachnoid haemorrhage	0.741	0.259
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.739	0.260
N93 Other abnormal uterine and vaginal bleeding	0.737	0.263
Y83.4 Other reconstructive surgery	0.736	0.264
T79-T79 Certain early complications of trauma	0.734	0.265
S00-S09 Injuries to the head	0.732	0.268
Chapter X Diseases of the respiratory system	0.731	0.269
T15-T19 Effects of foreign body entering through natural orifice	0.729	0.271
N10-N16 Renal tubulo-interstitial diseases	0.728	0.272
B35-B49 Mycoses	0.727	0.273
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.727	0.273
I05-I09 Chronic rheumatic heart diseases	0.725	0.275
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.724	0.276
M45-M49 Spondylopathies	0.723	0.277
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.723	0.277
Chapter VII Diseases of the eye and adnexa	0.723	0.277
T78 Adverse effects, not elsewhere classified	0.722	0.278
R73.9 Hyperglycaemia, unspecified	0.720	0.279
N84 Polyp of female genital tract	0.720	0.280
N70-N77 Inflammatory diseases of female pelvic organs	0.720	0.280
R45 Symptoms and signs involving emotional state	0.719	0.280
K55-K64 Other diseases of intestines	0.719	0.281
I77 Other disorders of arteries and arterioles	0.718	0.281
K65 Peritonitis	0.717	0.283
Chapter XXII Codes for special purposes	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
R90 Abnormal findings on diagnostic imaging of central nervous system	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.716	0.283
I00-I02 Acute rheumatic fever	0.716	0.284
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.716	0.284
R68 Other general symptoms and signs	0.716	0.284
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.716	0.284
R62 Lack of expected normal physiological development	0.716	0.284
R57 Shock, not elsewhere classified	0.716	0.284
R64 Cachexia	0.716	0.284
R58 Haemorrhage, not elsewhere classified	0.716	0.284
K75 Other inflammatory liver diseases	0.715	0.285
C43-C44 Melanoma and other malignant neoplasms of skin	0.715	0.285
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.714	0.286
Y35-Y36 Legal intervention and operations of war	0.714	0.286
Y10-Y34 Event of undetermined intent	0.714	0.286
Y00-Y09 Assault	0.714	0.286
X85-X99 Assault	0.714	0.286
X58-X59 Accidental exposure to other and unspecified factors	0.714	0.286
X50-X57 Overexertion, travel and privation	0.714	0.286
X40-X49 Accidental poisoning by and exposure to noxious substances	0.714	0.286
X30-X39 Exposure to forces of nature	0.714	0.286
X10-X19 Contact with heat and hot substances	0.714	0.286
X00-X09 Exposure to smoke, fire and flames	0.714	0.286
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.714	0.286
W75-W84 Other accidental threats to breathing	0.714	0.286
W65-W74 Accidental drowning and submersion	0.714	0.286
W50-W64 Exposure to animate mechanical forces	0.714	0.286
V98-V99 Other and unspecified transport accidents	0.714	0.286
V95-V97 Air and space transport accidents	0.714	0.286
V90-V94 Water transport accidents	0.714	0.286
V80-V89 Other land transport accidents	0.714	0.286
V70-V79 Bus occupant injured in transport accident	0.714	0.286
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.714	0.286
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.714	0.286
V40-V49 Car occupant injured in transport accident	0.714	0.286
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.714	0.286
V20-V29 Motorcycle rider injured in transport accident	0.714	0.286
V01-V09 Pedestrian injured in transport accident	0.714	0.286
I78 Diseases of capillaries	0.713	0.287
D60-D64 Aplastic and other anaemias	0.712	0.288
R30-R39 Symptoms and signs involving the urinary system	0.711	0.289
R79 Other abnormal findings of blood chemistry	0.711	0.289
K40 Inguinal hernia	0.708	0.292
R54 Senility	0.707	0.293
I44 Atrioventricular and left bundle-branch block	0.705	0.295
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.705	0.295
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.704	0.296
I95 Hypotension	0.704	0.296
N17-N19 Renal failure	0.703	0.297
K74 Fibrosis and cirrhosis of liver	0.702	0.298
R76 Other abnormal immunological findings in serum	0.700	0.300
R44 Other symptoms and signs involving general sensations and perceptions	0.700	0.300
S52 Fracture of forearm	0.700	0.300
I62 Other nontraumatic intracranial haemorrhage	0.700	0.300
R59 Enlarged lymph nodes	0.698	0.302
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.695	0.305
K51.3 Ulcerative (chronic) rectosigmoiditis	0.694	0.306
X23 Contact with hornets, wasps and bees	0.692	0.308
I71 Aortic aneurysm and dissection	0.690	0.310
Y59 Other and unspecified vaccines and biological substances	0.687	0.313
Y58 Bacterial vaccines	0.687	0.313
Y57 Other and unspecified drugs and medicaments	0.687	0.313
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.687	0.313
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.687	0.313
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.687	0.313
Y53 Agents primarily affecting the gastro-intestinal system	0.687	0.313
Y51 Drugs primarily affecting the autonomic nervous system	0.687	0.313
Y50 Central nervous system stimulants, not elsewhere classified	0.687	0.313
Y49 Psychotropic drugs, not elsewhere classified	0.687	0.313
Y48 Anaesthetics and therapeutic gases	0.687	0.313
Y47 Sedatives, hypnotics and antianxiety drugs	0.687	0.313
Y46 Antiepileptics and anti-Parkinsonism drugs	0.687	0.313
Y44 Agents primarily affecting blood constituents	0.687	0.313
Y41 Other systemic anti-infectives and antiparasitics	0.687	0.313
S70 Superficial injury of hip and thigh	0.686	0.314
C60-C63 Malignant neoplasms of male genital organs	0.685	0.314
T51.0 Ethanol	0.685	0.314
B99-B99 Other infectious diseases	0.684	0.316
B90-B94 Sequelae of infectious and parasitic diseases	0.684	0.316
B85-B89 Pediculosis, acariasis and other infestations	0.684	0.316
B65-B83 Helminthiases	0.684	0.316
B50-B64 Protozoal diseases	0.684	0.316
B20-B24 Human immunodeficiency virus [HIV] disease	0.684	0.316
B15-B19 Viral hepatitis	0.684	0.316
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.684	0.316
A80-A89 Viral infections of the central nervous system	0.684	0.316
A75-A79 Rickettsioses	0.684	0.316
A70-A74 Other diseases caused by chlamydiae	0.684	0.316
A65-A69 Other spirochaetal diseases	0.684	0.316
A50-A64 Infections with a predominantly sexual mode of transmission	0.684	0.316
A20-A28 Certain zoonotic bacterial diseases	0.684	0.316
A15-A19 Tuberculosis	0.684	0.316
K90-K93 Other diseases of the digestive system	0.684	0.316
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.683	0.317
I52 Other heart disorders in diseases classified elsewhere	0.683	0.317
I48 Atrial fibrillation and flutter	0.683	0.317
I43 Cardiomyopathy in diseases classified elsewhere	0.683	0.317
I41 Myocarditis in diseases classified elsewhere	0.683	0.317
I40 Acute myocarditis	0.683	0.317
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.683	0.317
I37 Pulmonary valve disorders	0.683	0.317
I36 Nonrheumatic tricuspid valve disorders	0.683	0.317
I32 Pericarditis in diseases classified elsewhere	0.683	0.317
I30 Acute pericarditis	0.683	0.317
I38 Endocarditis, valve unspecified	0.683	0.317
G35-G37 Demyelinating diseases of the central nervous system	0.683	0.317
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters	0.681	0.319
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.681	0.319
R73.0 Abnormal glucose tolerance test	0.678	0.322
K50.8 Other Crohn's disease	0.678	0.322
Y43 Primarily systemic agents	0.678	0.322
I24 Other acute ischaemic heart diseases	0.677	0.323
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.677	0.323
I72 Other aneurysm	0.677	0.323
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.677	0.323
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.677	0.323
I68 Cerebrovascular disorders in diseases classified elsewhere	0.676	0.323
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.676	0.323
S51 Open wound of forearm	0.676	0.323
C64-C68 Malignant neoplasms of urinary tract	0.676	0.324
T63.4 Venom of other arthropods	0.676	0.324
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.675	0.325
I47 Paroxysmal tachycardia	0.675	0.325
I22 Subsequent myocardial infarction	0.675	0.325
Y60-Y69 Misadventures to patients during surgical and medical care	0.674	0.326
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.674	0.326
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.674	0.326
R40 Somnolence, stupor and coma	0.674	0.326
T86 Failure and rejection of transplanted organs and tissues	0.673	0.326
Y83.8 Other surgical procedures	0.673	0.327
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.673	0.327
I46 Cardiac arrest	0.673	0.327
S99 Other and unspecified injuries of ankle and foot	0.672	0.327
W29 Contact with other powered hand tools and household machinery	0.672	0.328
R61.9 Hyperhidrosis, unspecified	0.672	0.328
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.671	0.329
R92 Abnormal findings on diagnostic imaging of breast	0.670	0.330
T85 Complications of other internal prosthetic devices, implants and grafts	0.669	0.331
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.669	0.331
K77 Liver disorders in diseases classified elsewhere	0.668	0.331
K73 Chronic hepatitis, not elsewhere classified	0.668	0.331
K71 Toxic liver disease	0.668	0.331
T88 Other complications of surgical and medical care, not elsewhere classified	0.668	0.332
N99-N99 Other disorders of the genitourinary system	0.667	0.333
D37-D48 Neoplasms of uncertain or unknown behaviour	0.667	0.333
G20-G26 Extrapyramidal and movement disorders	0.666	0.334
I98 Other disorders of circulatory system in diseases classified elsewhere	0.665	0.335
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.664	0.336
N84.0 Polyp of corpus uteri	0.664	0.336
Y45.0 Opioids and related analgesics	0.663	0.337
N86 Erosion and ectropion of cervix uteri	0.663	0.337
S72.0 Fracture of neck of femur	0.661	0.338
J80-J84 Other respiratory diseases principally affecting the interstitium	0.661	0.339
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.660	0.340
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.658	0.342
M80-M85 Disorders of bone density and structure	0.658	0.342
K51.4 Pseudopolyposis of colon	0.657	0.343
R78 Findings of drugs and other substances, not normally found in blood	0.656	0.343
R77 Other abnormalities of plasma proteins	0.656	0.343
R74 Abnormal serum enzyme levels	0.656	0.343
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.656	0.343
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.656	0.343
R72 Abnormality of white blood cells, not elsewhere classified	0.656	0.343
R71 Abnormality of red blood cells	0.656	0.343
K70 Alcoholic liver disease	0.655	0.345
K35-K38 Diseases of appendix	0.655	0.345
Y83.1 Surgical operation with implant of artificial internal device	0.654	0.346
M86-M90 Other osteopathies	0.654	0.346
Y95 Nosocomial condition	0.651	0.349
R94.3 Abnormal results of cardiovascular function studies	0.651	0.349
T40.2 Other opioids	0.651	0.349
C44 Other malignant neoplasms of skin	0.650	0.350
S89 Other and unspecified injuries of lower leg	0.650	0.350
K46 Unspecified abdominal hernia	0.650	0.350
T65 Toxic effect of other and unspecified substances	0.649	0.350
T62 Toxic effect of other noxious substances eaten as food	0.649	0.350
T61 Toxic effect of noxious substances eaten as seafood	0.649	0.350
T60 Toxic effect of pesticides	0.649	0.350
T59 Toxic effect of other gases, fumes and vapours	0.649	0.350
T57 Toxic effect of other inorganic substances	0.649	0.350
T56 Toxic effect of metals	0.649	0.350
T54 Toxic effect of corrosive substances	0.649	0.350
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.649	0.350
T52 Toxic effect of organic solvents	0.649	0.350
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.649	0.350
T58 Toxic effect of carbon monoxide	0.649	0.350
T55 Toxic effect of soaps and detergents	0.649	0.350
I61 Intracerebral haemorrhage	0.649	0.351
Y42.5 Other oestrogens and progestogens	0.648	0.352
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.647	0.353
I67.1 Cerebral aneurysm, nonruptured	0.647	0.353
R56 Convulsions, not elsewhere classified	0.647	0.353
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.646	0.354
I64 Stroke, not specified as haemorrhage or infarction	0.646	0.354
Y83.0 Surgical operation with transplant of whole organ	0.645	0.355
R52.9 Pain, unspecified	0.645	0.355
R52.0 Acute pain	0.645	0.355
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.644	0.356
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.643	0.356
I49 Other cardiac arrhythmias	0.643	0.357
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.643	0.357
G51 Facial nerve disorders	0.642	0.358
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.641	0.359
R46 Symptoms and signs involving appearance and behaviour	0.640	0.359
R43 Disturbances of smell and taste	0.640	0.359
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.640	0.360
I34.8 Other nonrheumatic mitral valve disorders	0.640	0.360
I34.2 Nonrheumatic mitral (valve) stenosis	0.640	0.360
N25-N29 Other disorders of kidney and ureter	0.639	0.361
Chapter VIII Diseases of the ear and mastoid process	0.637	0.363
C51-C58 Malignant neoplasms of female genital organs	0.637	0.363
K76.8 Other specified diseases of liver	0.637	0.363
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.636	0.363
J40-J47 Chronic lower respiratory diseases	0.636	0.364
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.635	0.365
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.635	0.365
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.635	0.365
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.635	0.365
T46 Poisoning by agents primarily affecting the cardiovascular system	0.635	0.365
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.635	0.365
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.635	0.365
T41 Poisoning by anaesthetics and therapeutic gases	0.635	0.365
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.635	0.365
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.635	0.365
T36 Poisoning by systemic antibiotics	0.635	0.365
D80-D89 Certain disorders involving the immune mechanism	0.635	0.365
K45 Other abdominal hernia	0.635	0.365
A41 Other septicaemia	0.634	0.365
N93.0 Postcoital and contact bleeding	0.634	0.366
S64 Injury of nerves at wrist and hand level	0.634	0.366
I45.9 Conduction disorder, unspecified	0.634	0.366
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.634	0.366
M05 Seropositive rheumatoid arthritis	0.634	0.366
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.634	0.366
T39.1 4-Aminophenol derivatives	0.633	0.367
K76.6 Portal hypertension	0.633	0.367
Y42.9 Other and unspecified hormone antagonists	0.633	0.367
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.633	0.367
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.633	0.367
Y42.4 Oral contraceptives	0.633	0.367
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.633	0.367
Y42.2 Antithyroid drugs	0.633	0.367
Y42.1 Thyroid hormones and substitutes	0.633	0.367
Y42.0 Glucocorticoids and synthetic analogs	0.633	0.367
A08 Viral and other specified intestinal infections	0.630	0.370
D68 Other coagulation defects	0.630	0.370
K65.0 Acute peritonitis	0.630	0.370
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.629	0.371
M10 Gout	0.629	0.371
M65-M68 Disorders of synovium and tendon	0.628	0.372
S82.6 Fracture of lateral malleolus	0.628	0.372
S79 Other and unspecified injuries of hip and thigh	0.627	0.372
S78 Traumatic amputation of hip and thigh	0.627	0.372
S77 Crushing injury of hip and thigh	0.627	0.372
S76 Injury of muscle and tendon at hip and thigh level	0.627	0.372
S75 Injury of blood vessels at hip and thigh level	0.627	0.372
S74 Injury of nerves at hip and thigh level	0.627	0.372
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.627	0.372
S71 Open wound of hip and thigh	0.627	0.372
B97 Viral agents as the cause of diseases classified to other chapters	0.627	0.373
I50 Heart failure	0.627	0.373
V18 Pedal cyclist injured in noncollision transport accident	0.627	0.373
T87 Complications peculiar to reattachment and amputation	0.626	0.374
T80 Complications following infusion, transfusion and therapeutic injection	0.626	0.374
G90-G99 Other disorders of the nervous system	0.625	0.375
G70-G73 Diseases of myoneural junction and muscle	0.625	0.375
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.625	0.375
G00-G09 Inflammatory diseases of the central nervous system	0.625	0.375
W22 Striking against or struck by other objects	0.625	0.375
K72.0 Acute and subacute hepatic failure	0.625	0.375
S82.8 Fractures of other parts of lower leg	0.624	0.376
K63 Other diseases of intestine	0.624	0.376
H53-H54 Visual disturbances and blindness	0.624	0.376
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.624	0.376
M91-M94 Chondropathies	0.624	0.376
M60-M63 Disorders of muscles	0.624	0.376
M00-M03 Infectious arthropathies	0.624	0.376
M40-M43 Deforming dorsopathies	0.624	0.376
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.624	0.376
N18 Chronic renal failure	0.622	0.378
M47 Spondylosis	0.622	0.378
K41 Femoral hernia	0.622	0.378
B25-B34 Other viral diseases	0.621	0.379
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.621	0.379
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.621	0.379
G30-G32 Other degenerative diseases of the nervous system	0.621	0.379
I31.3 Pericardial effusion (noninflammatory)	0.620	0.380
I74.5 Embolism and thrombosis of iliac artery	0.620	0.380
I42.2 Other hypertrophic cardiomyopathy	0.620	0.380
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.619	0.381
S88 Traumatic amputation of lower leg	0.618	0.381
S87 Crushing injury of lower leg	0.618	0.381
S86 Injury of muscle and tendon at lower leg level	0.618	0.381
S85 Injury of blood vessels at lower leg level	0.618	0.381
S84 Injury of nerves at lower leg level	0.618	0.381
S81 Open wound of lower leg	0.618	0.381
Y40.8 Other systemic antibiotics	0.617	0.382
I42.0 Dilated cardiomyopathy	0.617	0.383
I23 Certain current complications following acute myocardial infarction	0.617	0.383
M70-M79 Other soft tissue disorders	0.616	0.384
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.615	0.385
R93.6 Abnormal findings on diagnostic imaging of limbs	0.615	0.385
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.615	0.385
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.615	0.385
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.614	0.386
K51.8 Other ulcerative colitis	0.614	0.386
I67.7 Cerebral arteritis, not elsewhere classified	0.614	0.386
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.614	0.386
I67.5 Moyamoya disease	0.614	0.386
I67.4 Hypertensive encephalopathy	0.614	0.386
I67.3 Progressive vascular leukoencephalopathy	0.614	0.386
I67.2 Cerebral atherosclerosis	0.614	0.386
I67.0 Dissection of cerebral arteries, nonruptured	0.614	0.386
K51.9 Ulcerative colitis, unspecified	0.613	0.387
S67 Crushing injury of wrist and hand	0.613	0.387
N75 Diseases of Bartholin's gland	0.612	0.387
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.611	0.388
S92 Fracture of foot, except ankle	0.611	0.389
I63.8 Other cerebral infarction	0.611	0.389
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.611	0.389
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.611	0.389
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.611	0.389
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.611	0.389
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.611	0.389
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.611	0.389
I45.1 Other and unspecified right bundle-branch block	0.610	0.390
Y83.6 Removal of other organ (partial) (total)	0.610	0.390
C44.5 Skin of trunk	0.610	0.390
G80-G83 Cerebral palsy and other paralytic syndromes	0.609	0.391
S59 Other and unspecified injuries of forearm	0.609	0.391
S58 Traumatic amputation of forearm	0.609	0.391
S57 Crushing injury of forearm	0.609	0.391
S56 Injury of muscle and tendon at forearm level	0.609	0.391
S55 Injury of blood vessels at forearm level	0.609	0.391
S54 Injury of nerves at forearm level	0.609	0.391
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.609	0.391
S50 Superficial injury of forearm	0.609	0.391
C64 Malignant neoplasm of kidney, except renal pelvis	0.609	0.391
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.608	0.392
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.608	0.392
D55-D59 Haemolytic anaemias	0.607	0.393
I67.8 Other specified cerebrovascular diseases	0.607	0.393
A09.9 Gastroenteritis and colitis of unspecified origin	0.607	0.393
R23 Other skin changes	0.606	0.394
T84.1 Mechanical complication of internal fixation device of bones of limb	0.606	0.394
G50 Disorders of trigeminal nerve	0.606	0.394
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.606	0.394
I33.0 Acute and subacute infective endocarditis	0.605	0.395
I42.9 Cardiomyopathy, unspecified	0.605	0.395
K76.7 Hepatorenal syndrome	0.604	0.395
K76.5 Hepatic veno-occlusive disease	0.604	0.395
K76.4 Peliosis hepatis	0.604	0.395
K76.3 Infarction of liver	0.604	0.395
K76.2 Central haemorrhagic necrosis of liver	0.604	0.395
K76.1 Chronic passive congestion of liver	0.604	0.395

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations