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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80002115
log Bayes Factor = 18.6774
Chromosome 13   position 93,812,032  (GRCh37) Explore rs80002115 on Ensembl!
Variant rs80002115 is part of Cluster X0161

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Chapter I Certain infectious and parasitic diseases
0.999 0.001 0.000
H30-H36 Disorders of choroid and retina
0.999 0.001 0.000
H35 Other retinal disorders
0.995 0.005 0.000
Chapter X Diseases of the respiratory system
0.994 0.006 0.000
Chapter XI Diseases of the digestive system
0.994 0.006 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.988 0.012 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.984 0.016 0.000
H35.3 Degeneration of macula and posterior pole
0.983 0.017 0.000
N30-N39 Other diseases of urinary system
0.974 0.026 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.974 0.026 0.000
A30-A49 Other bacterial diseases
0.972 0.028 0.000
J20-J22 Other acute lower respiratory infections
0.970 0.030 0.000
M20-M25 Other joint disorders
0.965 0.035 0.000
K90-K93 Other diseases of the digestive system
0.962 0.038 0.000
Chapter VI Diseases of the nervous system
0.958 0.042 0.000
J90-J94 Other diseases of pleura
0.956 0.044 0.000
J22 Unspecified acute lower respiratory infection
0.954 0.046 0.000
B95-B98 Bacterial, viral and other infectious agents
0.953 0.047 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.952 0.048 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.950 0.050 0.000
R50-R69 General symptoms and signs
0.947 0.053 0.000
A41 Other septicaemia
0.946 0.054 0.000
M80-M85 Disorders of bone density and structure
0.946 0.054 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.945 0.055 0.000
N20-N23 Urolithiasis
0.943 0.057 0.000
M15-M19 Arthrosis
0.942 0.058 0.000
M70-M79 Other soft tissue disorders
0.938 0.062 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.934 0.066 0.000
K92 Other diseases of digestive system
0.934 0.066 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.928 0.072 0.000
J90 Pleural effusion, not elsewhere classified
0.920 0.080 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.916 0.084 0.000
N25-N29 Other disorders of kidney and ureter
0.915 0.085 0.000
B25-B34 Other viral diseases
0.914 0.086 0.000
R69 Unknown and unspecified causes of morbidity
0.909 0.091 0.000
M81 Osteoporosis without pathological fracture
0.908 0.092 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.908 0.092 0.000
T39.1 4-Aminophenol derivatives
0.903 0.097 0.000
R06 Abnormalities of breathing
0.903 0.097 0.000
S80-S89 Injuries to the knee and lower leg
0.901 0.099 0.000
N32 Other disorders of bladder
0.900 0.100 0.000
M23 Internal derangement of knee
0.898 0.102 0.000
N30 Cystitis
0.898 0.102 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.896 0.104 0.000
N20 Calculus of kidney and ureter
0.895 0.105 0.000
A41.9 Septicaemia, unspecified
0.894 0.106 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.894 0.106 0.000
G90-G99 Other disorders of the nervous system
0.889 0.111 0.000
H33 Retinal detachments and breaks
0.886 0.114 0.000
N80 Endometriosis
0.885 0.115 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.884 0.116 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.884 0.116 0.000
M81.9 Osteoporosis, unspecified
0.881 0.119 0.000
K50-K52 Noninfective enteritis and colitis
0.877 0.123 0.000
H36 Retinal disorders in diseases classified elsewhere
0.876 0.124 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.874 0.126 0.000
S70-S79 Injuries to the hip and thigh
0.873 0.127 0.000
J00-J06 Acute upper respiratory infections
0.869 0.131 0.000
K01 Embedded and impacted teeth
0.865 0.134 0.000
K92.1 Melaena
0.865 0.135 0.000
D50-D53 Nutritional anaemias
0.859 0.141 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.858 0.142 0.000
N20.0 Calculus of kidney
0.856 0.144 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.854 0.146 0.000
N99-N99 Other disorders of the genitourinary system
0.852 0.148 0.000
M19 Other arthrosis
0.850 0.150 0.000
M75 Shoulder lesions
0.847 0.153 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.846 0.154 0.000
M17 Gonarthrosis [arthrosis of knee]
0.843 0.157 0.000
M05-M14 Inflammatory polyarthropathies
0.843 0.157 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.843 0.157 0.000
H35.9 Retinal disorder, unspecified
0.842 0.158 0.000
H40-H42 Glaucoma
0.841 0.159 0.000
N30.9 Cystitis, unspecified
0.841 0.159 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.841 0.159 0.000
R06.0 Dyspnoea
0.841 0.159 0.000
H55-H59 Other disorders of eye and adnexa
0.841 0.159 0.000
M22 Disorders of patella
0.839 0.161 0.000
B35-B49 Mycoses
0.835 0.165 0.000
K08 Other disorders of teeth and supporting structures
0.835 0.165 0.000
N17-N19 Renal failure
0.832 0.168 0.000
B34 Viral infection of unspecified site
0.831 0.169 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.831 0.169 0.000
H35.8 Other specified retinal disorders
0.831 0.169 0.000
E10-E14 Diabetes mellitus
0.831 0.169 0.000
N95 Menopausal and other perimenopausal disorders
0.829 0.170 0.000
K51 Ulcerative colitis
0.829 0.171 0.000
N88 Other noninflammatory disorders of cervix uteri
0.826 0.174 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.825 0.175 0.000
Chapter IX Diseases of the circulatory system
0.823 0.177 0.000
N80.9 Endometriosis, unspecified
0.822 0.178 0.000
H33.3 Retinal breaks without detachment
0.821 0.179 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.821 0.179 0.000
K12 Stomatitis and related lesions
0.818 0.182 0.000
Chapter XX External causes of morbidity and mortality
0.817 0.183 0.000
K55-K64 Other diseases of intestines
0.813 0.187 0.000
N10-N16 Renal tubulo-interstitial diseases
0.812 0.188 0.000
R05 Cough
0.811 0.189 0.000
N35 Urethral stricture
0.808 0.192 0.000
G93 Other disorders of brain
0.808 0.192 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.808 0.192 0.000
R52 Pain, not elsewhere classified
0.805 0.195 0.000
B15-B19 Viral hepatitis
0.803 0.197 0.000
M50-M54 Other dorsopathies
0.802 0.198 0.000
N00-N08 Glomerular diseases
0.800 0.200 0.000
H35.6 Retinal haemorrhage
0.798 0.202 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.798 0.202 0.000
N89 Other noninflammatory disorders of vagina
0.797 0.203 0.000
R53 Malaise and fatigue
0.796 0.204 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.794 0.206 0.000
T40.2 Other opioids
0.794 0.206 0.000
H34 Retinal vascular occlusions
0.794 0.206 0.000
R09.1 Pleurisy
0.793 0.207 0.000
H10-H13 Disorders of conjunctiva
0.791 0.209 0.000
K35-K38 Diseases of appendix
0.791 0.209 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.790 0.210 0.000
K14 Diseases of tongue
0.789 0.211 0.000
K58 Irritable bowel syndrome
0.788 0.212 0.000
K01.1 Impacted teeth
0.788 0.212 0.000
S10-S19 Injuries to the neck
0.788 0.212 0.000
H36.0 Diabetic retinopathy
0.788 0.212 0.000
N73 Other female pelvic inflammatory diseases
0.788 0.212 0.000
K02 Dental caries
0.787 0.213 0.000
M24 Other specific joint derangements
0.787 0.213 0.000
K13 Other diseases of lip and oral mucosa
0.785 0.215 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.784 0.216 0.000
S72 Fracture of femur
0.782 0.218 0.000
M65-M68 Disorders of synovium and tendon
0.782 0.218 0.000
G40-G47 Episodic and paroxysmal disorders
0.781 0.219 0.000
R06.4 Hyperventilation
0.780 0.220 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.778 0.222 0.000
M18 Arthrosis of first carpometacarpal joint
0.778 0.222 0.000
R94 Abnormal results of function studies
0.776 0.224 0.000
K90 Intestinal malabsorption
0.776 0.224 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.775 0.225 0.000
A46 Erysipelas
0.774 0.226 0.000
K92.0 Haematemesis
0.773 0.227 0.000
B34.9 Viral infection, unspecified
0.772 0.228 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.772 0.228 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.771 0.229 0.000
M40-M43 Deforming dorsopathies
0.771 0.229 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.770 0.230 0.000
D80-D89 Certain disorders involving the immune mechanism
0.769 0.231 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.769 0.231 0.000
D50 Iron deficiency anaemia
0.766 0.234 0.000
N32.0 Bladder-neck obstruction
0.765 0.235 0.000
S82 Fracture of lower leg, including ankle
0.762 0.238 0.000
K07 Dentofacial anomalies [including malocclusion]
0.760 0.240 0.000
N28.8 Other specified disorders of kidney and ureter
0.760 0.240 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.760 0.240 0.000
K51.9 Ulcerative colitis, unspecified
0.760 0.240 0.000
N60-N64 Disorders of breast
0.759 0.241 0.000
S40-S49 Injuries to the shoulder and upper arm
0.759 0.241 0.000
N97 Female infertility
0.757 0.243 0.000
M77 Other enthesopathies
0.756 0.244 0.000
M75.4 Impingement syndrome of shoulder
0.755 0.245 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.754 0.246 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.754 0.246 0.000
N93 Other abnormal uterine and vaginal bleeding
0.753 0.247 0.000
M31 Other necrotising vasculopathies
0.753 0.247 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.750 0.250 0.000
M23.4 Loose body in knee
0.750 0.250 0.000
M17.0 Primary gonarthrosis, bilateral
0.750 0.250 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.748 0.252 0.000
G30-G32 Other degenerative diseases of the nervous system
0.747 0.252 0.000
T81 Complications of procedures, not elsewhere classified
0.747 0.253 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.746 0.254 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.745 0.255 0.000
S90-S99 Injuries to the ankle and foot
0.745 0.255 0.000
N32.9 Bladder disorder, unspecified
0.744 0.256 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.743 0.256 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.743 0.257 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.743 0.257 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.742 0.258 0.000
E65-E68 Obesity and other hyperalimentation
0.741 0.259 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.740 0.260 0.000
R06.8 Other and unspecified abnormalities of breathing
0.737 0.263 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.736 0.264 0.000
M86-M90 Other osteopathies
0.735 0.265 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.735 0.265 0.000
J93 Pneumothorax
0.734 0.266 0.000
M21 Other acquired deformities of limbs
0.734 0.266 0.000
J02 Acute pharyngitis
0.734 0.266 0.000
J60-J70 Lung diseases due to external agents
0.732 0.267 0.000
I05-I09 Chronic rheumatic heart diseases
0.732 0.268 0.000
H18 Other disorders of cornea
0.731 0.269 0.000
K65-K67 Diseases of peritoneum
0.730 0.270 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.730 0.270 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.730 0.270 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.729 0.271 0.000
H40 Glaucoma
0.728 0.272 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.727 0.273 0.000
T66-T78 Other and unspecified effects of external causes
0.727 0.273 0.000
M23.8 Other internal derangements of knee
0.727 0.273 0.000
G95 Other diseases of spinal cord
0.727 0.273 0.000
S50-S59 Injuries to the elbow and forearm
0.726 0.274 0.000
N32.3 Diverticulum of bladder
0.726 0.274 0.000
M23.3 Other meniscus derangements
0.726 0.274 0.000
R63 Symptoms and signs concerning food and fluid intake
0.726 0.274 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.726 0.274 0.000
K11 Diseases of salivary glands
0.724 0.275 0.000
R56 Convulsions, not elsewhere classified
0.724 0.276 0.000
M35 Other systemic involvement of connective tissue
0.723 0.277 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.723 0.277 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.723 0.277 0.000
I26 Pulmonary embolism
0.723 0.277 0.000
B25 Cytomegaloviral disease
0.722 0.278 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.721 0.279 0.000
N36 Other disorders of urethra
0.721 0.279 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.721 0.279 0.000
G40 Epilepsy
0.721 0.279 0.000
T40.4 Other synthetic narcotics
0.721 0.279 0.000
S81 Open wound of lower leg
0.721 0.279 0.000
N87 Dysplasia of cervix uteri
0.721 0.279 0.000
J95-J99 Other diseases of the respiratory system
0.721 0.279 0.000
L40-L45 Papulosquamous disorders
0.720 0.280 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.719 0.281 0.000
G20-G26 Extrapyramidal and movement disorders
0.719 0.281 0.000
B37 Candidiasis
0.718 0.282 0.000
J09-J18 Influenza and pneumonia
0.718 0.282 0.000
D51 Vitamin B12 deficiency anaemia
0.718 0.282 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.717 0.283 0.000
N28.1 Cyst of kidney, acquired
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.716 0.284 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.716 0.284 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.716 0.284 0.000
B65-B83 Helminthiases
0.716 0.284 0.000
B50-B64 Protozoal diseases
0.716 0.284 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.716 0.284 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.716 0.284 0.000
A80-A89 Viral infections of the central nervous system
0.716 0.284 0.000
A75-A79 Rickettsioses
0.716 0.284 0.000
A70-A74 Other diseases caused by chlamydiae
0.716 0.284 0.000
A65-A69 Other spirochaetal diseases
0.716 0.284 0.000
A20-A28 Certain zoonotic bacterial diseases
0.716 0.284 0.000
A15-A19 Tuberculosis
0.716 0.284 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.716 0.284 0.000
H31 Other disorders of choroid
0.716 0.284 0.000
H30 Chorioretinal inflammation
0.716 0.284 0.000
S00-S09 Injuries to the head
0.715 0.285 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.715 0.285 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.715 0.285 0.000
J84 Other interstitial pulmonary diseases
0.714 0.286 0.000
H35.7 Separation of retinal layers
0.713 0.286 0.000
H35.5 Hereditary retinal dystrophy
0.713 0.286 0.000
H35.4 Peripheral retinal degeneration
0.713 0.286 0.000
H35.2 Other proliferative retinopathy
0.713 0.286 0.000
H35.1 Retinopathy of prematurity
0.713 0.286 0.000
H35.0 Background retinopathy and retinal vascular changes
0.713 0.286 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.713 0.287 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.712 0.288 0.000
R60 Oedema, not elsewhere classified
0.710 0.290 0.000
Chapter VIII Diseases of the ear and mastoid process
0.709 0.291 0.000
N23 Unspecified renal colic
0.709 0.291 0.000
N88.2 Stricture and stenosis of cervix uteri
0.709 0.291 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.708 0.291 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.708 0.291 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.708 0.291 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.708 0.291 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.708 0.291 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.708 0.291 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.708 0.291 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.708 0.291 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.708 0.291 0.000
T36 Poisoning by systemic antibiotics
0.708 0.291 0.000
R09.0 Asphyxia
0.708 0.292 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.708 0.292 0.000
K70-K77 Diseases of liver
0.707 0.293 0.000
H43-H45 Disorders of vitreous body and globe
0.707 0.293 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.706 0.294 0.000
R50 Fever of unknown origin
0.706 0.294 0.000
M19.9 Arthrosis, unspecified
0.706 0.294 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.705 0.295 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.705 0.295 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.704 0.296 0.000
L60-L75 Disorders of skin appendages
0.704 0.296 0.000
R52.9 Pain, unspecified
0.704 0.296 0.000
N70 Salpingitis and oophoritis
0.703 0.296 0.000
Chapter V Mental and behavioural disorders
0.702 0.298 0.000
M72 Fibroblastic disorders
0.701 0.299 0.000
R00 Abnormalities of heart beat
0.701 0.299 0.000
E10 Insulin-dependent diabetes mellitus
0.699 0.301 0.000
J92 Pleural plaque
0.699 0.301 0.000
H33.0 Retinal detachment with retinal break
0.699 0.301 0.000
N37 Urethral disorders in diseases classified elsewhere
0.699 0.301 0.000
N34 Urethritis and urethral syndrome
0.699 0.301 0.000
N33 Bladder disorders in diseases classified elsewhere
0.699 0.301 0.000
E50-E64 Other nutritional deficiencies
0.699 0.301 0.000
G93.3 Postviral fatigue syndrome
0.699 0.301 0.000
K10 Other diseases of jaws
0.698 0.302 0.000
K09 Cysts of oral region, not elsewhere classified
0.698 0.302 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.698 0.302 0.000
K03 Other diseases of hard tissues of teeth
0.698 0.302 0.000
K00 Disorders of tooth development and eruption
0.698 0.302 0.000
N73.6 Female pelvic peritoneal adhesions
0.698 0.302 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.697 0.303 0.000
A48 Other bacterial diseases, not elsewhere classified
0.697 0.303 0.000
A44 Bartonellosis
0.697 0.303 0.000
A43 Nocardiosis
0.697 0.303 0.000
A42 Actinomycosis
0.697 0.303 0.000
A40 Streptococcal septicaemia
0.697 0.303 0.000
A39 Meningococcal infection
0.697 0.303 0.000
A37 Whooping cough
0.697 0.303 0.000
A36 Diphtheria
0.697 0.303 0.000
A32 Listeriosis
0.697 0.303 0.000
A31 Infection due to other mycobacteria
0.697 0.303 0.000
A30 Leprosy [Hansen's disease]
0.697 0.303 0.000
A38 Scarlet fever
0.697 0.303 0.000
A35 Other tetanus
0.697 0.303 0.000
A34 Obstetrical tetanus
0.697 0.303 0.000
A33 Tetanus neonatorum
0.697 0.303 0.000
M22.4 Chondromalacia patellae
0.697 0.303 0.000
M75.0 Adhesive capsulitis of shoulder
0.697 0.303 0.000
M25 Other joint disorders, not elsewhere classified
0.697 0.303 0.000
M19.0 Primary arthrosis of other joints
0.696 0.304 0.000
J21 Acute bronchiolitis
0.696 0.304 0.000
J20 Acute bronchitis
0.696 0.304 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.696 0.304 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.695 0.305 0.000
N30.3 Trigonitis
0.695 0.305 0.000
N80.2 Endometriosis of Fallopian tube
0.695 0.305 0.000
E20-E35 Disorders of other endocrine glands
0.693 0.307 0.000
N17 Acute renal failure
0.692 0.308 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.692 0.308 0.000
M34 Systemic sclerosis
0.692 0.308 0.000
M33 Dermatopolymyositis
0.692 0.308 0.000
M32 Systemic lupus erythematosus
0.692 0.308 0.000
M30 Polyarteritis nodosa and related conditions
0.692 0.308 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.691 0.309 0.000
K12.1 Other forms of stomatitis
0.691 0.309 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.690 0.310 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.690 0.310 0.000
A49 Bacterial infection of unspecified site
0.689 0.310 0.000
N21 Calculus of lower urinary tract
0.689 0.311 0.000
S72.1 Pertrochanteric fracture
0.689 0.311 0.000
N35.9 Urethral stricture, unspecified
0.689 0.311 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.688 0.312 0.000
N95.8 Other specified menopausal and perimenopausal disorders
0.688 0.312 0.000
N80.8 Other endometriosis
0.687 0.313 0.000
G70-G73 Diseases of myoneural junction and muscle
0.687 0.313 0.000
M75.3 Calcific tendinitis of shoulder
0.687 0.313 0.000
M07 Psoriatic and enteropathic arthropathies
0.687 0.313 0.000
M22.2 Patellofemoral disorders
0.686 0.314 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.685 0.315 0.000
J94 Other pleural conditions
0.685 0.315 0.000
J91 Pleural effusion in conditions classified elsewhere
0.685 0.315 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.684 0.316 0.000
N95.0 Postmenopausal bleeding
0.683 0.317 0.000
N98 Complications associated with artificial fertilisation
0.683 0.317 0.000
N91 Absent, scanty and rare menstruation
0.683 0.317 0.000
N82 Fistulae involving female genital tract
0.683 0.317 0.000
N96 Habitual aborter
0.683 0.317 0.000
H55 Nystagmus and other irregular eye movements
0.682 0.318 0.000
D50.9 Iron deficiency anaemia, unspecified
0.681 0.319 0.000
H53-H54 Visual disturbances and blindness
0.681 0.319 0.000
N89.5 Stricture and atresia of vagina
0.680 0.320 0.000
R04 Haemorrhage from respiratory passages
0.680 0.320 0.000
M45-M49 Spondylopathies
0.679 0.320 0.000
R68 Other general symptoms and signs
0.679 0.321 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.679 0.321 0.000
R62 Lack of expected normal physiological development
0.679 0.321 0.000
R57 Shock, not elsewhere classified
0.679 0.321 0.000
R64 Cachexia
0.679 0.321 0.000
R58 Haemorrhage, not elsewhere classified
0.679 0.321 0.000
A41.8 Other specified septicaemia
0.679 0.321 0.000
A41.4 Septicaemia due to anaerobes
0.679 0.321 0.000
A41.3 Septicaemia due to Haemophilus influenzae
0.679 0.321 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.679 0.321 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.679 0.321 0.000
M85 Other disorders of bone density and structure
0.678 0.321 0.000
M84 Disorders of continuity of bone
0.678 0.321 0.000
M83 Adult osteomalacia
0.678 0.321 0.000
M82 Osteoporosis in diseases classified elsewhere
0.678 0.321 0.000
N20.1 Calculus of ureter
0.678 0.322 0.000
M80 Osteoporosis with pathological fracture
0.678 0.322 0.000
N85.4 Malposition of uterus
0.677 0.323 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.677 0.323 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.677 0.323 0.000
T39.4 Antirheumatics, not elsewhere classified
0.677 0.323 0.000
T39.2 Pyrazolone derivatives
0.677 0.323 0.000
T39.0 Salicylates
0.677 0.323 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.676 0.324 0.000
M19.1 Posttraumatic arthrosis of other joints
0.676 0.324 0.000
M15 Polyarthrosis
0.676 0.324 0.000
G93.6 Cerebral oedema
0.675 0.325 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.674 0.326 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.674 0.326 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.673 0.327 0.000
H40.2 Primary angle-closure glaucoma
0.673 0.327 0.000
M76 Enthesopathies of lower limb, excluding foot
0.672 0.328 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.672 0.328 0.000
M71 Other bursopathies
0.672 0.328 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.672 0.328 0.000
M17.1 Other primary gonarthrosis
0.672 0.328 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.672 0.328 0.000
E11 Non-insulin-dependent diabetes mellitus
0.672 0.328 0.000
H57 Other disorders of eye and adnexa
0.670 0.330 0.000
L20-L30 Dermatitis and eczema
0.670 0.330 0.000
D55-D59 Haemolytic anaemias
0.669 0.330 0.000
K92.9 Disease of digestive system, unspecified
0.669 0.330 0.000
K92.8 Other specified diseases of digestive system
0.669 0.330 0.000
E14 Unspecified diabetes mellitus
0.669 0.331 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.668 0.332 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.668 0.332 0.000
X60-X84 Intentional self-harm
0.667 0.333 0.000
R94.5 Abnormal results of liver function studies
0.667 0.333 0.000
M13 Other arthritis
0.666 0.334 0.000
K50 Crohn's disease [regional enteritis]
0.666 0.334 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.665 0.335 0.000
K51.2 Ulcerative (chronic) proctitis
0.665 0.335 0.000
K08.3 Retained dental root
0.665 0.335 0.000
J80 Adult respiratory distress syndrome
0.664 0.336 0.000
N13 Obstructive and reflux uropathy
0.663 0.337 0.000
B18 Chronic viral hepatitis
0.663 0.337 0.000
M81.98 Osteoporosis, unspecified (Other)
0.662 0.338 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.662 0.338 0.000
T43.2 Other and unspecified antidepressants
0.662 0.338 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.661 0.339 0.000
N30.8 Other cystitis
0.661 0.339 0.000
N04 Nephrotic syndrome
0.660 0.340 0.000
E70-E90 Metabolic disorders
0.659 0.341 0.000
K60 Fissure and fistula of anal and rectal regions
0.659 0.341 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.659 0.341 0.000
N32.8 Other specified disorders of bladder
0.659 0.341 0.000
J03 Acute tonsillitis
0.657 0.343 0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified
0.656 0.343 0.000
E40-E46 Malnutrition
0.656 0.343 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.656 0.344 0.000
N27 Small kidney of unknown cause
0.656 0.344 0.000
N25 Disorders resulting from impaired renal tubular function
0.656 0.344 0.000
N26 Unspecified contracted kidney
0.656 0.344 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.656 0.344 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.655 0.345 0.000
B33 Other viral diseases, not elsewhere classified
0.655 0.345 0.000
B30 Viral conjunctivitis
0.655 0.345 0.000
B27 Infectious mononucleosis
0.655 0.345 0.000
B26 Mumps
0.655 0.345 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.655 0.345 0.000
N39 Other disorders of urinary system
0.654 0.346 0.000
K35 Acute appendicitis
0.654 0.346 0.000
K13.0 Diseases of lips
0.654 0.346 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.654 0.346 0.000
S82.0 Fracture of patella
0.653 0.347 0.000
K02.9 Dental caries, unspecified
0.653 0.347 0.000
J81 Pulmonary oedema
0.653 0.347 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.653 0.347 0.000
H25-H28 Disorders of lens
0.652 0.348 0.000
D86 Sarcoidosis
0.652 0.348 0.000
M81.8 Other osteoporosis
0.651 0.349 0.000
M81.6 Localised osteoporosis [Lequesne]
0.651 0.349 0.000
M81.5 Idiopathic osteoporosis
0.651 0.349 0.000
M81.4 Drug-induced osteoporosis
0.651 0.349 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.651 0.349 0.000
M81.2 Osteoporosis of disuse
0.651 0.349 0.000
M81.1 Postoophorectomy osteoporosis
0.651 0.349 0.000
M81.0 Postmenopausal osteoporosis
0.651 0.349 0.000
T87 Complications peculiar to reattachment and amputation
0.651 0.349 0.000
T86 Failure and rejection of transplanted organs and tissues
0.651 0.349 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.651 0.349 0.000
R00.0 Tachycardia, unspecified
0.651 0.349 0.000
M65 Synovitis and tenosynovitis
0.649 0.351 0.000
K14.0 Glossitis
0.649 0.351 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.649 0.351 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.648 0.352 0.000
R06.7 Sneezing
0.647 0.353 0.000
R06.6 Hiccough
0.647 0.353 0.000
R06.3 Periodic breathing
0.647 0.353 0.000
R06.2 Wheezing
0.647 0.353 0.000
R06.1 Stridor
0.647 0.353 0.000
S20-S29 Injuries to the thorax
0.646 0.353 0.000
H34.8 Other retinal vascular occlusions
0.646 0.353 0.000
D69 Purpura and other haemorrhagic conditions
0.646 0.354 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.646 0.354 0.000
S89 Other and unspecified injuries of lower leg
0.646 0.354 0.000
S88 Traumatic amputation of lower leg
0.646 0.354 0.000
S87 Crushing injury of lower leg
0.646 0.354 0.000
S86 Injury of muscle and tendon at lower leg level
0.646 0.354 0.000
S85 Injury of blood vessels at lower leg level
0.646 0.354 0.000
S84 Injury of nerves at lower leg level
0.646 0.354 0.000
S80 Superficial injury of lower leg
0.646 0.354 0.000
M51 Other intervertebral disk disorders
0.646 0.354 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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