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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80008789
log Bayes Factor = 15.187
Chromosome 10   position 17,042,603  (GRCh37) Explore rs80008789 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.998 0.002 0.000
R50-R69 General symptoms and signs
0.998 0.002 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.995 0.005 0.000
Chapter II Neoplasms
0.995 0.005 0.000
J90-J94 Other diseases of pleura
0.988 0.012 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.987 0.013 0.000
R10.1 Pain localised to upper abdomen
0.987 0.013 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.987 0.013 0.000
R10 Abdominal and pelvic pain
0.985 0.015 0.000
R59 Enlarged lymph nodes
0.982 0.018 0.000
I73 Other peripheral vascular diseases
0.981 0.019 0.000
M20-M25 Other joint disorders
0.980 0.020 0.000
N17-N19 Renal failure
0.977 0.023 0.000
J40-J47 Chronic lower respiratory diseases
0.975 0.025 0.000
C15-C26 Malignant neoplasms of digestive organs
0.975 0.025 0.000
M05-M14 Inflammatory polyarthropathies
0.970 0.030 0.000
R11 Nausea and vomiting
0.970 0.030 0.000
Chapter XI Diseases of the digestive system
0.966 0.034 0.000
M23 Internal derangement of knee
0.963 0.037 0.000
J09-J18 Influenza and pneumonia
0.960 0.040 0.000
R59.0 Localised enlarged lymph nodes
0.960 0.040 0.000
I73.9 Peripheral vascular disease, unspecified
0.953 0.047 0.000
R53 Malaise and fatigue
0.951 0.049 0.000
I74 Arterial embolism and thrombosis
0.944 0.056 0.000
K70-K77 Diseases of liver
0.944 0.056 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.939 0.061 0.000
J92 Pleural plaque
0.939 0.061 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.938 0.062 0.000
Chapter VIII Diseases of the ear and mastoid process
0.936 0.064 0.000
N18 Chronic renal failure
0.935 0.065 0.000
J18 Pneumonia, organism unspecified
0.935 0.065 0.000
N84 Polyp of female genital tract
0.933 0.067 0.000
K55-K64 Other diseases of intestines
0.933 0.067 0.000
J43 Emphysema
0.924 0.076 0.000
M06 Other rheumatoid arthritis
0.923 0.077 0.000
J18.1 Lobar pneumonia, unspecified
0.920 0.080 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.909 0.091 0.000
J44 Other chronic obstructive pulmonary disease
0.909 0.091 0.000
N89 Other noninflammatory disorders of vagina
0.907 0.093 0.000
I77 Other disorders of arteries and arterioles
0.905 0.095 0.000
K76 Other diseases of liver
0.904 0.096 0.000
N19 Unspecified renal failure
0.904 0.096 0.000
M23.3 Other meniscus derangements
0.902 0.098 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.897 0.103 0.000
N18.9 Chronic renal failure, unspecified
0.897 0.103 0.000
J95-J99 Other diseases of the respiratory system
0.896 0.104 0.000
N92 Excessive, frequent and irregular menstruation
0.893 0.107 0.000
N84.1 Polyp of cervix uteri
0.892 0.108 0.000
M06.9 Rheumatoid arthritis, unspecified
0.890 0.110 0.000
J43.9 Emphysema, unspecified
0.887 0.113 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.886 0.114 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.886 0.114 0.000
K57 Diverticular disease of intestine
0.886 0.114 0.000
I05-I09 Chronic rheumatic heart diseases
0.886 0.114 0.000
R68 Other general symptoms and signs
0.886 0.114 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.884 0.116 0.000
H65-H75 Diseases of middle ear and mastoid
0.883 0.117 0.000
R79 Other abnormal findings of blood chemistry
0.882 0.118 0.000
M80-M85 Disorders of bone density and structure
0.878 0.122 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.877 0.123 0.000
J92.9 Pleural plaque without asbestos
0.876 0.124 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.876 0.124 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.875 0.125 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.864 0.136 0.000
C18 Malignant neoplasm of colon
0.862 0.138 0.000
I73.0 Raynaud's syndrome
0.861 0.139 0.000
K76.8 Other specified diseases of liver
0.860 0.140 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.858 0.142 0.000
R59.1 Generalised enlarged lymph nodes
0.857 0.143 0.000
N00-N08 Glomerular diseases
0.856 0.144 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.854 0.146 0.000
R51 Headache
0.853 0.147 0.000
I95 Hypotension
0.852 0.148 0.000
N81 Female genital prolapse
0.851 0.149 0.000
M22 Disorders of patella
0.851 0.149 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.849 0.151 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.847 0.153 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.847 0.153 0.000
S80-S89 Injuries to the knee and lower leg
0.842 0.158 0.000
I72 Other aneurysm
0.842 0.158 0.000
J93 Pneumothorax
0.842 0.158 0.000
R50 Fever of unknown origin
0.837 0.163 0.000
I10-I15 Hypertensive diseases
0.837 0.163 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.837 0.163 0.000
C51-C58 Malignant neoplasms of female genital organs
0.836 0.164 0.000
Chapter XXII Codes for special purposes
0.835 0.165 0.000
N10-N16 Renal tubulo-interstitial diseases
0.834 0.166 0.000
M24 Other specific joint derangements
0.832 0.168 0.000
C25 Malignant neoplasm of pancreas
0.832 0.168 0.000
J98 Other respiratory disorders
0.831 0.169 0.000
K62 Other diseases of anus and rectum
0.830 0.170 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.829 0.171 0.000
R61 Hyperhidrosis
0.825 0.175 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.821 0.179 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.821 0.179 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.820 0.180 0.000
M86-M90 Other osteopathies
0.818 0.182 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.814 0.186 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.814 0.186 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.814 0.186 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.814 0.186 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.813 0.187 0.000
J60-J70 Lung diseases due to external agents
0.811 0.189 0.000
Chapter VI Diseases of the nervous system
0.809 0.191 0.000
N95 Menopausal and other perimenopausal disorders
0.806 0.194 0.000
R68.8 Other specified general symptoms and signs
0.805 0.195 0.000
J90 Pleural effusion, not elsewhere classified
0.805 0.195 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.804 0.196 0.000
J91 Pleural effusion in conditions classified elsewhere
0.802 0.198 0.000
M65-M68 Disorders of synovium and tendon
0.799 0.201 0.000
J40 Bronchitis, not specified as acute or chronic
0.799 0.201 0.000
Chapter I Certain infectious and parasitic diseases
0.798 0.202 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.794 0.206 0.000
I12 Hypertensive renal disease
0.794 0.206 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.792 0.208 0.000
I95.9 Hypotension, unspecified
0.792 0.208 0.000
N92.3 Ovulation bleeding
0.792 0.208 0.000
N85.1 Endometrial adenomatous hyperplasia
0.790 0.210 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.789 0.211 0.000
M40-M43 Deforming dorsopathies
0.788 0.212 0.000
J94 Other pleural conditions
0.788 0.212 0.000
R52 Pain, not elsewhere classified
0.788 0.212 0.000
C64-C68 Malignant neoplasms of urinary tract
0.787 0.213 0.000
J92.0 Pleural plaque with presence of asbestos
0.787 0.213 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.785 0.215 0.000
G20-G26 Extrapyramidal and movement disorders
0.784 0.216 0.000
J98.1 Pulmonary collapse
0.783 0.217 0.000
R10.3 Pain localised to other parts of lower abdomen
0.783 0.217 0.000
T66-T78 Other and unspecified effects of external causes
0.783 0.217 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.781 0.219 0.000
N18.0 End-stage renal disease
0.781 0.219 0.000
M23.4 Loose body in knee
0.780 0.220 0.000
I08 Multiple valve diseases
0.779 0.221 0.000
H73 Other disorders of tympanic membrane
0.779 0.221 0.000
C60-C63 Malignant neoplasms of male genital organs
0.778 0.222 0.000
K74 Fibrosis and cirrhosis of liver
0.778 0.222 0.000
N85.0 Endometrial glandular hyperplasia
0.777 0.223 0.000
N89.5 Stricture and atresia of vagina
0.777 0.223 0.000
M10 Gout
0.777 0.223 0.000
C34 Malignant neoplasm of bronchus and lung
0.776 0.223 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.775 0.225 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.775 0.225 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.773 0.227 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.771 0.229 0.000
N03 Chronic nephritic syndrome
0.770 0.230 0.000
K76.9 Liver disease, unspecified
0.770 0.230 0.000
M31 Other necrotising vasculopathies
0.770 0.230 0.000
H72 Perforation of tympanic membrane
0.770 0.230 0.000
M13 Other arthritis
0.769 0.231 0.000
I99 Other and unspecified disorders of circulatory system
0.768 0.232 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.767 0.233 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.767 0.233 0.000
I74.5 Embolism and thrombosis of iliac artery
0.767 0.233 0.000
N97 Female infertility
0.766 0.234 0.000
R10.0 Acute abdomen
0.765 0.235 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.763 0.237 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.762 0.238 0.000
T79-T79 Certain early complications of trauma
0.761 0.239 0.000
N89.6 Tight hymenal ring
0.760 0.240 0.000
I12.0 Hypertensive renal disease with renal failure
0.760 0.240 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.759 0.241 0.000
C20 Malignant neoplasm of rectum
0.758 0.242 0.000
R12 Heartburn
0.758 0.242 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.756 0.244 0.000
I84 Haemorrhoids
0.756 0.244 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.755 0.245 0.000
M80 Osteoporosis with pathological fracture
0.755 0.245 0.000
H80-H83 Diseases of inner ear
0.751 0.248 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.750 0.250 0.000
S60-S69 Injuries to the wrist and hand
0.749 0.251 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.748 0.252 0.000
N40-N51 Diseases of male genital organs
0.748 0.252 0.000
K70 Alcoholic liver disease
0.746 0.254 0.000
O80-O84 Delivery
0.746 0.254 0.000
S00-S09 Injuries to the head
0.745 0.255 0.000
I77.1 Stricture of artery
0.745 0.255 0.000
M22.4 Chondromalacia patellae
0.743 0.257 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.743 0.257 0.000
R18 Ascites
0.742 0.258 0.000
I77.6 Arteritis, unspecified
0.742 0.258 0.000
K90-K93 Other diseases of the digestive system
0.739 0.261 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.739 0.261 0.000
I84.2 Internal haemorrhoids without complication
0.737 0.263 0.000
C18.5 Splenic flexure
0.735 0.265 0.000
R60 Oedema, not elsewhere classified
0.735 0.265 0.000
N18.5 Chronic kidney disease, stage 5
0.735 0.265 0.000
M45-M49 Spondylopathies
0.734 0.266 0.000
N13 Obstructive and reflux uropathy
0.733 0.266 0.000
M34 Systemic sclerosis
0.733 0.267 0.000
R63 Symptoms and signs concerning food and fluid intake
0.733 0.267 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.733 0.267 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.732 0.268 0.000
I70 Atherosclerosis
0.731 0.268 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.729 0.271 0.000
I80 Phlebitis and thrombophlebitis
0.728 0.272 0.000
C34.1 Upper lobe, bronchus or lung
0.728 0.272 0.000
G20 Parkinson's disease
0.728 0.272 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.728 0.272 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.727 0.273 0.000
T87 Complications peculiar to reattachment and amputation
0.727 0.273 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.727 0.273 0.000
J93.9 Pneumothorax, unspecified
0.727 0.273 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.724 0.276 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.724 0.276 0.000
M11 Other crystal arthropathies
0.723 0.277 0.000
N94.6 Dysmenorrhoea, unspecified
0.722 0.278 0.000
K65-K67 Diseases of peritoneum
0.721 0.279 0.000
K62.1 Rectal polyp
0.720 0.280 0.000
K60 Fissure and fistula of anal and rectal regions
0.719 0.281 0.000
C54 Malignant neoplasm of corpus uteri
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
N81.1 Cystocele
0.716 0.284 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.716 0.284 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.716 0.284 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.716 0.284 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.715 0.284 0.000
R62 Lack of expected normal physiological development
0.715 0.284 0.000
R57 Shock, not elsewhere classified
0.715 0.284 0.000
R64 Cachexia
0.715 0.284 0.000
R58 Haemorrhage, not elsewhere classified
0.715 0.284 0.000
N98 Complications associated with artificial fertilisation
0.713 0.286 0.000
N91 Absent, scanty and rare menstruation
0.713 0.286 0.000
N82 Fistulae involving female genital tract
0.713 0.286 0.000
N96 Habitual aborter
0.713 0.286 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.713 0.287 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.713 0.287 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.713 0.287 0.000
C18.7 Sigmoid colon
0.713 0.287 0.000
M23.8 Other internal derangements of knee
0.711 0.289 0.000
M05 Seropositive rheumatoid arthritis
0.710 0.290 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.710 0.290 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.709 0.290 0.000
N03.9 Unspecified
0.709 0.291 0.000
S82 Fracture of lower leg, including ankle
0.709 0.291 0.000
I85 Oesophageal varices
0.708 0.292 0.000
T33-T35 Frostbite
0.707 0.292 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.707 0.292 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.707 0.292 0.000
T00-T07 Injuries involving multiple body regions
0.707 0.292 0.000
S10-S19 Injuries to the neck
0.707 0.292 0.000
S90-S99 Injuries to the ankle and foot
0.707 0.293 0.000
S70-S79 Injuries to the hip and thigh
0.707 0.293 0.000
N81.5 Vaginal enterocele
0.707 0.293 0.000
N18.2 Chronic kidney disease, stage 2
0.707 0.293 0.000
K76.6 Portal hypertension
0.706 0.294 0.000
K75 Other inflammatory liver diseases
0.706 0.294 0.000
C15 Malignant neoplasm of oesophagus
0.706 0.294 0.000
N81.8 Other female genital prolapse
0.705 0.295 0.000
H73.8 Other specified disorders of tympanic membrane
0.704 0.296 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.703 0.297 0.000
I73.8 Other specified peripheral vascular diseases
0.703 0.297 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.703 0.297 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.703 0.297 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.703 0.297 0.000
M33 Dermatopolymyositis
0.703 0.297 0.000
M32 Systemic lupus erythematosus
0.703 0.297 0.000
M30 Polyarteritis nodosa and related conditions
0.703 0.297 0.000
T86 Failure and rejection of transplanted organs and tissues
0.702 0.298 0.000
R61.9 Hyperhidrosis, unspecified
0.702 0.298 0.000
R74 Abnormal serum enzyme levels
0.701 0.299 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.700 0.300 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.700 0.300 0.000
C32 Malignant neoplasm of larynx
0.700 0.300 0.000
J41 Simple and mucopurulent chronic bronchitis
0.699 0.301 0.000
G25 Other extrapyramidal and movement disorders
0.699 0.301 0.000
I86 Varicose veins of other sites
0.699 0.301 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.699 0.301 0.000
C21 Malignant neoplasm of anus and anal canal
0.699 0.301 0.000
C17 Malignant neoplasm of small intestine
0.699 0.301 0.000
C23 Malignant neoplasm of gallbladder
0.699 0.301 0.000
C26.0 Intestinal tract, part unspecified
0.699 0.301 0.000
D00-D09 In situ neoplasms
0.698 0.302 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.697 0.303 0.000
M70-M79 Other soft tissue disorders
0.697 0.303 0.000
M65 Synovitis and tenosynovitis
0.696 0.304 0.000
M14 Arthropathies in other diseases classified elsewhere
0.695 0.304 0.000
M12 Other specific arthropathies
0.695 0.304 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.695 0.304 0.000
M08 Juvenile arthritis
0.695 0.304 0.000
M07 Psoriatic and enteropathic arthropathies
0.695 0.304 0.000
R73 Elevated blood glucose level
0.695 0.305 0.000
I07 Rheumatic tricuspid valve diseases
0.695 0.305 0.000
N92.4 Excessive bleeding in the premenopausal period
0.695 0.305 0.000
N86 Erosion and ectropion of cervix uteri
0.694 0.306 0.000
R21 Rash and other nonspecific skin eruption
0.694 0.306 0.000
C80 Malignant neoplasm without specification of site
0.694 0.306 0.000
C18.6 Descending colon
0.693 0.306 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.693 0.307 0.000
M23.9 Internal derangement of knee, unspecified
0.691 0.309 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.691 0.309 0.000
M23.5 Chronic instability of knee
0.691 0.309 0.000
M23.1 Discoid meniscus (congenital)
0.691 0.309 0.000
M23.0 Cystic meniscus
0.691 0.309 0.000
O85-O92 Complications predominantly related to the puerperium
0.690 0.310 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.689 0.311 0.000
I78 Diseases of capillaries
0.689 0.311 0.000
J17 Pneumonia in diseases classified elsewhere
0.688 0.311 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.688 0.311 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.688 0.311 0.000
J12 Viral pneumonia, not elsewhere classified
0.688 0.311 0.000
J11 Influenza, virus not identified
0.688 0.311 0.000
J10 Influenza due to identified influenza virus
0.688 0.311 0.000
J14 Pneumonia due to Haemophilus influenzae
0.688 0.311 0.000
J09 Influenza due to certain identified influenza virus
0.688 0.311 0.000
N85.2 Hypertrophy of uterus
0.688 0.311 0.000
R23 Other skin changes
0.688 0.312 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.688 0.312 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.688 0.312 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.688 0.312 0.000
K55 Vascular disorders of intestine
0.687 0.313 0.000
S02 Fracture of skull and facial bones
0.686 0.313 0.000
K59 Other functional intestinal disorders
0.686 0.314 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.685 0.315 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.685 0.315 0.000
Chapter V Mental and behavioural disorders
0.685 0.315 0.000
N84.2 Polyp of vagina
0.684 0.316 0.000
M21 Other acquired deformities of limbs
0.683 0.317 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.682 0.318 0.000
K61 Abscess of anal and rectal regions
0.681 0.318 0.000
N90.5 Atrophy of vulva
0.681 0.319 0.000
C25.9 Pancreas, unspecified
0.681 0.319 0.000
T85.2 Mechanical complication of intraocular lens
0.681 0.319 0.000
I72.0 Aneurysm of carotid artery
0.681 0.319 0.000
S20-S29 Injuries to the thorax
0.681 0.319 0.000
C18.4 Transverse colon
0.679 0.321 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.679 0.321 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.678 0.322 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.678 0.322 0.000
N50 Other disorders of male genital organs
0.678 0.322 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.677 0.323 0.000
I74.8 Embolism and thrombosis of other arteries
0.677 0.323 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.677 0.323 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.677 0.323 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.677 0.323 0.000
K77 Liver disorders in diseases classified elsewhere
0.676 0.323 0.000
K73 Chronic hepatitis, not elsewhere classified
0.676 0.323 0.000
K71 Toxic liver disease
0.676 0.323 0.000
H65 Nonsuppurative otitis media
0.677 0.323 0.000
I72.4 Aneurysm of artery of lower extremity
0.675 0.325 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.673 0.327 0.000
R77 Other abnormalities of plasma proteins
0.673 0.327 0.000
R76 Other abnormal immunological findings in serum
0.673 0.327 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.673 0.327 0.000
R71 Abnormality of red blood cells
0.673 0.327 0.000
K72 Hepatic failure, not elsewhere classified
0.673 0.327 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.673 0.327 0.000
O80 Single spontaneous delivery
0.672 0.328 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.671 0.328 0.000
M81 Osteoporosis without pathological fracture
0.671 0.328 0.000
N95.0 Postmenopausal bleeding
0.671 0.329 0.000
C25.0 Head of pancreas
0.671 0.329 0.000
N18.8 Other chronic renal failure
0.671 0.329 0.000
N18.1 Chronic kidney disease, stage 1
0.671 0.329 0.000
J18.8 Other pneumonia, organism unspecified
0.670 0.330 0.000
J18.2 Hypostatic pneumonia, unspecified
0.670 0.330 0.000
N84.9 Polyp of female genital tract, unspecified
0.669 0.331 0.000
N84.8 Polyp of other parts of female genital tract
0.669 0.331 0.000
N84.3 Polyp of vulva
0.669 0.331 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.669 0.331 0.000
N94.3 Premenstrual tension syndrome
0.668 0.332 0.000
N90.4 Leukoplakia of vulva
0.667 0.333 0.000
H71 Cholesteatoma of middle ear
0.666 0.334 0.000
R20 Disturbances of skin sensation
0.666 0.334 0.000
O00-O08 Pregnancy with abortive outcome
0.665 0.335 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.665 0.335 0.000
N88 Other noninflammatory disorders of cervix uteri
0.665 0.335 0.000
K92 Other diseases of digestive system
0.665 0.335 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.663 0.337 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.663 0.337 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.663 0.337 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.663 0.337 0.000
R59.9 Enlarged lymph nodes, unspecified
0.662 0.337 0.000
C22.9 Liver, unspecified
0.662 0.338 0.000
J43.8 Other emphysema
0.662 0.338 0.000
J43.2 Centrilobular emphysema
0.662 0.338 0.000
J43.1 Panlobular emphysema
0.662 0.338 0.000
J43.0 MacLeod's syndrome
0.662 0.338 0.000
R22.1 Localised swelling, mass and lump, neck
0.662 0.338 0.000
R56 Convulsions, not elsewhere classified
0.662 0.338 0.000
M06.8 Other specified rheumatoid arthritis
0.662 0.338 0.000
M06.4 Inflammatory polyarthropathy
0.662 0.338 0.000
M06.3 Rheumatoid nodule
0.662 0.338 0.000
M06.2 Rheumatoid bursitis
0.662 0.338 0.000
M06.1 Adult-onset Still's disease
0.662 0.338 0.000
M06.0 Seronegative rheumatoid arthritis
0.662 0.338 0.000
M41 Scoliosis
0.662 0.338 0.000
R94 Abnormal results of function studies
0.661 0.339 0.000
K62.7 Radiation proctitis
0.661 0.339 0.000
M24.1 Other articular cartilage disorders
0.660 0.340 0.000
C22.0 Liver cell carcinoma
0.660 0.340 0.000
J45 Asthma
0.659 0.341 0.000
R54 Senility
0.658 0.342 0.000
M24.0 Loose body in joint
0.657 0.343 0.000
R50.0 Fever with chills
0.657 0.343 0.000
N99-N99 Other disorders of the genitourinary system
0.656 0.343 0.000
K05 Gingivitis and periodontal diseases
0.656 0.344 0.000
H90-H95 Other disorders of ear
0.656 0.344 0.000
I87 Other disorders of veins
0.656 0.344 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.656 0.344 0.000
C79 Secondary malignant neoplasm of other sites
0.656 0.344 0.000
R52.1 Chronic intractable pain
0.656 0.344 0.000
R50.9 Fever, unspecified
0.656 0.344 0.000
J69 Pneumonitis due to solids and liquids
0.654 0.346 0.000
M85 Other disorders of bone density and structure
0.653 0.346 0.000
I95.1 Orthostatic hypotension
0.653 0.347 0.000
M90 Osteopathies in diseases classified elsewhere
0.653 0.347 0.000
N72 Inflammatory disease of cervix uteri
0.651 0.349 0.000
N89.9 Noninflammatory disorder of vagina, unspecified
0.650 0.350 0.000
N89.7 Haematocolpos
0.650 0.350 0.000
N89.4 Leukoplakia of vagina
0.650 0.350 0.000
N89.3 Dysplasia of vagina, unspecified
0.650 0.350 0.000
N89.2 Severe vaginal dysplasia, not elsewhere classified
0.650 0.350 0.000
N89.1 Moderate vaginal dysplasia
0.650 0.350 0.000
N89.0 Mild vaginal dysplasia
0.650 0.350 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.650 0.350 0.000
T39.1 4-Aminophenol derivatives
0.649 0.351 0.000
I77.8 Other specified disorders of arteries and arterioles
0.649 0.351 0.000
I77.5 Necrosis of artery
0.649 0.351 0.000
I77.4 Coeliac artery compression syndrome
0.649 0.351 0.000
I77.3 Arterial fibromuscular dysplasia
0.649 0.351 0.000
I77.2 Rupture of artery
0.649 0.351 0.000
I77.0 Arteriovenous fistula, acquired
0.649 0.351 0.000
M23.49 Loose body in knee-Unspec lig/men
0.649 0.351 0.000
N70 Salpingitis and oophoritis
0.649 0.351 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.648 0.352 0.000
K76.7 Hepatorenal syndrome
0.648 0.352 0.000
K76.5 Hepatic veno-occlusive disease
0.648 0.352 0.000
K76.4 Peliosis hepatis
0.648 0.352 0.000
K76.3 Infarction of liver
0.648 0.352 0.000
K76.2 Central haemorrhagic necrosis of liver
0.648 0.352 0.000
K76.1 Chronic passive congestion of liver
0.648 0.352 0.000
T51 Toxic effect of alcohol
0.648 0.352 0.000
J42 Unspecified chronic bronchitis
0.647 0.353 0.000
M23.37 Other meniscus derangements-Capsular lig
0.647 0.353 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.647 0.353 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.647 0.353 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.647 0.353 0.000
M22.8 Other disorders of patella
0.646 0.353 0.000
S40-S49 Injuries to the shoulder and upper arm
0.646 0.354 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.646 0.354 0.000
C88 Malignant immunoproliferative diseases
0.646 0.354 0.000
M84 Disorders of continuity of bone
0.644 0.356 0.000
J94.8 Other specified pleural conditions
0.644 0.356 0.000
T40.2 Other opioids
0.644 0.356 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.644 0.356 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.643 0.357 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.643 0.357 0.000
J96 Respiratory failure, not elsewhere classified
0.643 0.357 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.642 0.357 0.000
C62 Malignant neoplasm of testis
0.642 0.357 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.642 0.358 0.000
B99-B99 Other infectious diseases
0.641 0.359 0.000
K04 Diseases of pulp and periapical tissues
0.641 0.359 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.641 0.359 0.000
R50.8 Other specified fever
0.641 0.359 0.000
N92.5 Other specified irregular menstruation
0.640 0.360 0.000
N92.2 Excessive menstruation at puberty
0.640 0.360 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.640 0.360 0.000
M35 Other systemic involvement of connective tissue
0.639 0.360 0.000
M10.9 Gout, unspecified
0.639 0.361 0.000
Chapter XX External causes of morbidity and mortality
0.639 0.361 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.638 0.362 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.638 0.362 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.638 0.362 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.638 0.362 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.638 0.362 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.638 0.362 0.000
S81 Open wound of lower leg
0.638 0.362 0.000
Q50-Q56 Congenital malformations of genital organs
0.638 0.362 0.000
J18.9 Pneumonia, unspecified
0.637 0.363 0.000
T78 Adverse effects, not elsewhere classified
0.636 0.364 0.000
N85.7 Haematometra
0.636 0.364 0.000
N85.6 Intra-uterine synechiae
0.636 0.364 0.000
N85.5 Inversion of uterus
0.636 0.364 0.000
N85.3 Subinvolution of uterus
0.636 0.364 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.636 0.364 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.635 0.364 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.635 0.364 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.635 0.364 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.635 0.364 0.000
I88 Nonspecific lymphadenitis
0.635 0.364 0.000
I81 Portal vein thrombosis
0.635 0.364 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.635 0.365 0.000
I09 Other rheumatic heart diseases
0.635 0.365 0.000
I06 Rheumatic aortic valve diseases
0.635 0.365 0.000
I05 Rheumatic mitral valve diseases
0.635 0.365 0.000
R68.3 Clubbing of fingers
0.635 0.365 0.000
R68.2 Dry mouth, unspecified
0.635 0.365 0.000
R68.1 Nonspecific symptoms peculiar to infancy
0.635 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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