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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80204783
log Bayes Factor = 12.4343
Chromosome 4   position 9,894,371  (GRCh37) Explore rs80204783 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
C15-C26 Malignant neoplasms of digestive organs
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
O36 Maternal care for other known or suspected foetal problems
0.998 0.002 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.997 0.003 0.000
O36.8 Maternal care for other specified foetal problems
0.995 0.005 0.000
R50-R69 General symptoms and signs
0.994 0.006 0.000
Chapter VIII Diseases of the ear and mastoid process
0.991 0.009 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.991 0.009 0.000
H65-H75 Diseases of middle ear and mastoid
0.989 0.011 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.988 0.012 0.000
M70-M79 Other soft tissue disorders
0.988 0.012 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.987 0.013 0.000
M79.8 Other specified soft tissue disorders
0.985 0.015 0.000
R51 Headache
0.982 0.018 0.000
C15 Malignant neoplasm of oesophagus
0.979 0.021 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.976 0.024 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.976 0.024 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.971 0.029 0.000
Chapter XI Diseases of the digestive system
0.968 0.032 0.000
Chapter V Mental and behavioural disorders
0.968 0.032 0.000
K92 Other diseases of digestive system
0.967 0.033 0.000
K90-K93 Other diseases of the digestive system
0.967 0.033 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.966 0.034 0.000
Chapter VI Diseases of the nervous system
0.964 0.036 0.000
K92.1 Melaena
0.963 0.037 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.958 0.042 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.955 0.045 0.000
F30-F39 Mood [affective] disorders
0.948 0.052 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.941 0.059 0.000
C18 Malignant neoplasm of colon
0.937 0.063 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.937 0.063 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.933 0.067 0.000
G20-G26 Extrapyramidal and movement disorders
0.928 0.072 0.000
H71 Cholesteatoma of middle ear
0.926 0.074 0.000
C15.9 Oesophagus, unspecified
0.924 0.076 0.000
R25 Abnormal involuntary movements
0.919 0.081 0.000
Chapter XXI Factors influencing health status and contact with health services
0.915 0.085 0.000
O43 Placental disorders
0.909 0.091 0.000
Z80 Family history of malignant neoplasm
0.908 0.092 0.000
R52 Pain, not elsewhere classified
0.908 0.092 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.907 0.093 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.907 0.093 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.905 0.095 0.000
M05-M14 Inflammatory polyarthropathies
0.903 0.097 0.000
C85.1 B-cell lymphoma, unspecified
0.902 0.098 0.000
C15.5 Lower third of oesophagus
0.899 0.101 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.897 0.103 0.000
R63 Symptoms and signs concerning food and fluid intake
0.897 0.103 0.000
C77.2 Intra-abdominal lymph nodes
0.894 0.106 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.894 0.106 0.000
R21 Rash and other nonspecific skin eruption
0.893 0.107 0.000
M10 Gout
0.892 0.108 0.000
H65 Nonsuppurative otitis media
0.892 0.108 0.000
M86-M90 Other osteopathies
0.890 0.110 0.000
C18.7 Sigmoid colon
0.887 0.113 0.000
Chapter I Certain infectious and parasitic diseases
0.887 0.113 0.000
H69 Other disorders of Eustachian tube
0.886 0.114 0.000
M10.9 Gout, unspecified
0.885 0.115 0.000
M10.99 Gout, unspecified (Site unspecified)
0.877 0.123 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.876 0.124 0.000
R29.6 Tendency to fall, not elsewhere classified
0.871 0.129 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.869 0.131 0.000
R63.0 Anorexia
0.866 0.134 0.000
M79.6 Pain in limb
0.863 0.137 0.000
Z98 Other postsurgical states
0.862 0.138 0.000
C78.0 Secondary malignant neoplasm of lung
0.861 0.139 0.000
M80-M85 Disorders of bone density and structure
0.857 0.143 0.000
G25 Other extrapyramidal and movement disorders
0.857 0.143 0.000
O36.5 Maternal care for poor foetal growth
0.855 0.145 0.000
F31 Bipolar affective disorder
0.855 0.145 0.000
F32 Depressive episode
0.855 0.145 0.000
R71 Abnormality of red blood cells
0.852 0.148 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.851 0.149 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.851 0.149 0.000
O20 Haemorrhage in early pregnancy
0.847 0.153 0.000
C78.2 Secondary malignant neoplasm of pleura
0.846 0.154 0.000
K55-K64 Other diseases of intestines
0.840 0.160 0.000
B95-B98 Bacterial, viral and other infectious agents
0.840 0.160 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.840 0.160 0.000
M45-M49 Spondylopathies
0.840 0.160 0.000
H66 Suppurative and unspecified otitis media
0.838 0.161 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.838 0.162 0.000
O43.8 Other placental disorders
0.837 0.163 0.000
C18.6 Descending colon
0.835 0.165 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.833 0.167 0.000
G20 Parkinson's disease
0.833 0.167 0.000
Z83 Family history of other specific disorders
0.833 0.167 0.000
M65-M68 Disorders of synovium and tendon
0.832 0.167 0.000
K92.9 Disease of digestive system, unspecified
0.832 0.168 0.000
C77.9 Lymph node, unspecified
0.831 0.169 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.829 0.171 0.000
O42 Premature rupture of membranes
0.827 0.173 0.000
K59 Other functional intestinal disorders
0.827 0.173 0.000
R53 Malaise and fatigue
0.827 0.173 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.823 0.177 0.000
O46.9 Antepartum haemorrhage, unspecified
0.819 0.181 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.817 0.183 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.816 0.184 0.000
H65.3 Chronic mucoid otitis media
0.814 0.186 0.000
C77.5 Intrapelvic lymph nodes
0.814 0.186 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.812 0.188 0.000
R73 Elevated blood glucose level
0.811 0.189 0.000
M79.0 Rheumatism, unspecified
0.809 0.191 0.000
C51-C58 Malignant neoplasms of female genital organs
0.809 0.191 0.000
O36.9 Maternal care for foetal problem, unspecified
0.809 0.191 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.808 0.192 0.000
K70-K77 Diseases of liver
0.807 0.193 0.000
H74 Other disorders of middle ear and mastoid
0.807 0.193 0.000
D00-D09 In situ neoplasms
0.807 0.193 0.000
K59.0 Constipation
0.805 0.195 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.804 0.196 0.000
G90-G99 Other disorders of the nervous system
0.803 0.197 0.000
F31.9 Bipolar affective disorder, unspecified
0.802 0.198 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.801 0.199 0.000
R79 Other abnormal findings of blood chemistry
0.800 0.200 0.000
M60-M63 Disorders of muscles
0.798 0.201 0.000
R52.1 Chronic intractable pain
0.796 0.204 0.000
C77.1 Intrathoracic lymph nodes
0.796 0.204 0.000
O41 Other disorders of amniotic fluid and membranes
0.795 0.205 0.000
R55 Syncope and collapse
0.793 0.207 0.000
R25.1 Tremor, unspecified
0.791 0.209 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.791 0.209 0.000
C88 Malignant immunoproliferative diseases
0.790 0.209 0.000
O23 Infections of genito-urinary tract in pregnancy
0.790 0.209 0.000
Z98.0 Intestinal bypass and anastomosis status
0.789 0.211 0.000
Chapter XXII Codes for special purposes
0.789 0.211 0.000
R25.3 Fasciculation
0.788 0.212 0.000
Z97 Presence of other devices
0.788 0.212 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.787 0.213 0.000
M89 Other disorders of bone
0.786 0.214 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.784 0.216 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.784 0.216 0.000
M00-M03 Infectious arthropathies
0.783 0.217 0.000
R57 Shock, not elsewhere classified
0.783 0.217 0.000
C50-C50 Malignant neoplasm of breast
0.783 0.217 0.000
K65-K67 Diseases of peritoneum
0.783 0.217 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.779 0.221 0.000
F99-F99 Unspecified mental disorder
0.779 0.221 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.777 0.223 0.000
M67 Other disorders of synovium and tendon
0.776 0.224 0.000
O28 Abnormal findings on antenatal screening of mother
0.775 0.225 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.774 0.226 0.000
R52.9 Pain, unspecified
0.774 0.226 0.000
Z85 Personal history of malignant neoplasm
0.773 0.227 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.771 0.229 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.768 0.232 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.768 0.232 0.000
H73 Other disorders of tympanic membrane
0.767 0.233 0.000
K70 Alcoholic liver disease
0.766 0.234 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.765 0.235 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.765 0.235 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.764 0.236 0.000
O24 Diabetes mellitus in pregnancy
0.764 0.236 0.000
C20 Malignant neoplasm of rectum
0.764 0.236 0.000
Z83.7 Family history of diseases of the digestive system
0.761 0.239 0.000
H69.9 Eustachian tube disorder, unspecified
0.760 0.240 0.000
F34 Persistent mood [affective] disorders
0.759 0.241 0.000
R59 Enlarged lymph nodes
0.758 0.242 0.000
C77.4 Inguinal and lower limb lymph nodes
0.758 0.242 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.757 0.243 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.757 0.243 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.756 0.244 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.755 0.244 0.000
R20 Disturbances of skin sensation
0.755 0.245 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.755 0.245 0.000
O44 Placenta praevia
0.754 0.246 0.000
O42.9 Premature rupture of membranes, unspecified
0.753 0.247 0.000
M71 Other bursopathies
0.747 0.253 0.000
O40 Polyhydramnios
0.746 0.253 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.746 0.254 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.745 0.255 0.000
K63 Other diseases of intestine
0.744 0.256 0.000
M46 Other inflammatory spondylopathies
0.744 0.256 0.000
C56 Malignant neoplasm of ovary
0.743 0.257 0.000
F30 Manic episode
0.743 0.257 0.000
M10.96 Gout, unspecified (Lower leg)
0.743 0.257 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.742 0.257 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.742 0.258 0.000
C91 Lymphoid leukaemia
0.741 0.259 0.000
R23 Other skin changes
0.741 0.259 0.000
H69.8 Other specified disorders of Eustachian tube
0.740 0.259 0.000
M91-M94 Chondropathies
0.740 0.260 0.000
Z80.3 Family history of malignant neoplasm of breast
0.739 0.261 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.739 0.261 0.000
M50-M54 Other dorsopathies
0.738 0.262 0.000
R25.2 Cramp and spasm
0.738 0.262 0.000
C15.4 Middle third of oesophagus
0.737 0.263 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.737 0.263 0.000
F33 Recurrent depressive disorder
0.736 0.264 0.000
H66.9 Otitis media, unspecified
0.736 0.264 0.000
C18.2 Ascending colon
0.736 0.264 0.000
C17 Malignant neoplasm of small intestine
0.735 0.265 0.000
O85-O92 Complications predominantly related to the puerperium
0.733 0.266 0.000
M84 Disorders of continuity of bone
0.733 0.267 0.000
H72 Perforation of tympanic membrane
0.732 0.268 0.000
G70-G73 Diseases of myoneural junction and muscle
0.732 0.268 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.731 0.269 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.731 0.269 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.729 0.271 0.000
C71 Malignant neoplasm of brain
0.728 0.272 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.728 0.272 0.000
C25 Malignant neoplasm of pancreas
0.727 0.273 0.000
K59.8 Other specified functional intestinal disorders
0.725 0.275 0.000
Q60-Q64 Congenital malformations of the urinary system
0.722 0.278 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.722 0.278 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.720 0.280 0.000
O36.6 Maternal care for excessive foetal growth
0.719 0.281 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.718 0.282 0.000
O80-O84 Delivery
0.718 0.282 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.718 0.282 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.717 0.283 0.000
O45 Premature separation of placenta [abruptio placentae]
0.717 0.283 0.000
O33 Maternal care for known or suspected disproportion
0.717 0.283 0.000
O31 Complications specific to multiple gestation
0.717 0.283 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.716 0.284 0.000
C23 Malignant neoplasm of gallbladder
0.716 0.284 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.716 0.284 0.000
O36.4 Maternal care for intra-uterine death
0.716 0.284 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.716 0.284 0.000
O36.2 Maternal care for hydrops foetalis
0.716 0.284 0.000
O36.1 Maternal care for other isoimmunisation
0.716 0.284 0.000
M79.66 Pain in limb (Lower leg)
0.716 0.284 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.715 0.285 0.000
O30 Multiple gestation
0.714 0.285 0.000
C16 Malignant neoplasm of stomach
0.714 0.286 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.713 0.287 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.713 0.287 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.713 0.287 0.000
R62 Lack of expected normal physiological development
0.713 0.287 0.000
R64 Cachexia
0.713 0.287 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.712 0.288 0.000
Z83.6 Family history of diseases of the respiratory system
0.711 0.289 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.711 0.289 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.710 0.290 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.710 0.290 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.709 0.291 0.000
H70 Mastoiditis and related conditions
0.709 0.291 0.000
H68 Eustachian salpingitis and obstruction
0.709 0.291 0.000
H67 Otitis media in diseases classified elsewhere
0.709 0.291 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.709 0.291 0.000
C95 Leukaemia of unspecified cell type
0.709 0.291 0.000
C94 Other leukaemias of specified cell type
0.709 0.291 0.000
C93 Monocytic leukaemia
0.709 0.291 0.000
C86 Other specified types of T/NK-cell lymphoma
0.709 0.291 0.000
M76 Enthesopathies of lower limb, excluding foot
0.708 0.291 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.708 0.291 0.000
M79.9 Soft tissue disorder, unspecified
0.708 0.292 0.000
M79.3 Panniculitis, unspecified
0.708 0.292 0.000
M79.2 Neuralgia and neuritis, unspecified
0.708 0.292 0.000
K63.2 Fistula of intestine
0.707 0.293 0.000
M79.88 Other specified soft tissue disorders (Other)
0.706 0.293 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.706 0.293 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.706 0.293 0.000
R73.9 Hyperglycaemia, unspecified
0.707 0.293 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.706 0.294 0.000
G25.0 Essential tremor
0.706 0.294 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.705 0.295 0.000
Z98.8 Other specified postsurgical states
0.704 0.296 0.000
Z89 Acquired absence of limb
0.704 0.296 0.000
M79.60 Pain in limb (Multiple sites)
0.702 0.298 0.000
C15.8 Overlapping lesion of oesophagus
0.702 0.298 0.000
C15.3 Upper third of oesophagus
0.702 0.298 0.000
C15.2 Abdominal part of oesophagus
0.702 0.298 0.000
C15.1 Thoracic part of oesophagus
0.702 0.298 0.000
C15.0 Cervical part of oesophagus
0.702 0.298 0.000
O46.8 Other antepartum haemorrhage
0.702 0.298 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.702 0.298 0.000
M79.63 Pain in limb (Forearm)
0.701 0.299 0.000
A30-A49 Other bacterial diseases
0.700 0.300 0.000
M87 Osteonecrosis
0.699 0.301 0.000
R68 Other general symptoms and signs
0.698 0.301 0.000
Chapter XX External causes of morbidity and mortality
0.698 0.302 0.000
R63.3 Feeding difficulties and mismanagement
0.697 0.303 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.697 0.303 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.696 0.304 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.696 0.304 0.000
R27 Other lack of coordination
0.695 0.305 0.000
Q80-Q89 Other congenital malformations
0.695 0.305 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.695 0.305 0.000
Q00-Q07 Congenital malformations of the nervous system
0.694 0.306 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.694 0.306 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.694 0.306 0.000
F70-F79 Mental retardation
0.694 0.306 0.000
K92.8 Other specified diseases of digestive system
0.694 0.306 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.693 0.307 0.000
M79.5 Residual foreign body in soft tissue
0.692 0.307 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.692 0.308 0.000
C85.0 Lymphosarcoma
0.692 0.308 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.691 0.309 0.000
M79.67 Pain in limb (Ankle and foot)
0.691 0.309 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.689 0.311 0.000
Z86 Personal history of certain other diseases
0.689 0.311 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.688 0.311 0.000
C18.9 Colon, unspecified
0.688 0.312 0.000
H65.4 Other chronic nonsuppurative otitis media
0.687 0.313 0.000
G40-G47 Episodic and paroxysmal disorders
0.687 0.313 0.000
A65-A69 Other spirochaetal diseases
0.685 0.315 0.000
O29 Complications of anaesthesia during pregnancy
0.684 0.315 0.000
O22 Venous complications in pregnancy
0.684 0.315 0.000
O25 Malnutrition in pregnancy
0.684 0.315 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.684 0.316 0.000
M20-M25 Other joint disorders
0.684 0.316 0.000
G30-G32 Other degenerative diseases of the nervous system
0.682 0.318 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.682 0.318 0.000
S70-S79 Injuries to the hip and thigh
0.682 0.318 0.000
Z98.1 Arthrodesis status
0.682 0.318 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.681 0.319 0.000
Z86.0 Personal history of other neoplasms
0.681 0.319 0.000
F38 Other mood [affective] disorders
0.680 0.320 0.000
F39 Unspecified mood [affective] disorder
0.680 0.320 0.000
R60 Oedema, not elsewhere classified
0.680 0.320 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.679 0.321 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.679 0.321 0.000
C18.1 Appendix
0.677 0.322 0.000
R61 Hyperhidrosis
0.677 0.323 0.000
H90-H95 Other disorders of ear
0.677 0.323 0.000
O43.1 Malformation of placenta
0.676 0.324 0.000
O20.0 Threatened abortion
0.676 0.324 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.675 0.325 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.675 0.325 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.675 0.325 0.000
R77 Other abnormalities of plasma proteins
0.675 0.325 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.675 0.325 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.675 0.325 0.000
R63.5 Abnormal weight gain
0.675 0.325 0.000
H80-H83 Diseases of inner ear
0.674 0.326 0.000
R52.2 Other chronic pain
0.674 0.326 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.674 0.326 0.000
G93 Other disorders of brain
0.673 0.327 0.000
K70.3 Alcoholic cirrhosis of liver
0.673 0.327 0.000
C18.8 Overlapping lesion of colon
0.672 0.328 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.672 0.328 0.000
M82 Osteoporosis in diseases classified elsewhere
0.669 0.330 0.000
M89.8 Other specified disorders of bone
0.669 0.331 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.669 0.331 0.000
R29.4 Clicking hip
0.669 0.331 0.000
R29.3 Abnormal posture
0.669 0.331 0.000
R29.2 Abnormal reflex
0.669 0.331 0.000
R29.1 Meningismus
0.669 0.331 0.000
R29.0 Tetany
0.669 0.331 0.000
G24 Dystonia
0.668 0.331 0.000
C21 Malignant neoplasm of anus and anal canal
0.668 0.332 0.000
M67.0 Short Achilles tendon (acquired)
0.667 0.333 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.667 0.333 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.666 0.333 0.000
F32.1 Moderate depressive episode
0.666 0.334 0.000
G23 Other degenerative diseases of basal ganglia
0.666 0.334 0.000
G21 Secondary Parkinsonism
0.666 0.334 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.666 0.334 0.000
G22 Parkinsonism in diseases classified elsewhere
0.666 0.334 0.000
K63.1 Perforation of intestine (nontraumatic)
0.665 0.335 0.000
M90 Osteopathies in diseases classified elsewhere
0.665 0.335 0.000
R54 Senility
0.665 0.335 0.000
M79.1 Myalgia
0.665 0.335 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.665 0.335 0.000
R79.0 Abnormal level of blood mineral
0.664 0.336 0.000
C80 Malignant neoplasm without specification of site
0.663 0.336 0.000
K05 Gingivitis and periodontal diseases
0.663 0.337 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.663 0.337 0.000
M88 Paget's disease of bone [osteitis deformans]
0.663 0.337 0.000
M85 Other disorders of bone density and structure
0.661 0.339 0.000
K10 Other diseases of jaws
0.660 0.339 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.660 0.340 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.659 0.341 0.000
C81 Hodgkin's disease
0.659 0.341 0.000
R25.0 Abnormal head movements
0.659 0.341 0.000
R58 Haemorrhage, not elsewhere classified
0.659 0.341 0.000
M67.1 Other contracture of tendon (sheath)
0.659 0.341 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.658 0.342 0.000
C77.8 Lymph nodes of multiple regions
0.658 0.342 0.000
K66 Other disorders of peritoneum
0.657 0.343 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.657 0.343 0.000
M72 Fibroblastic disorders
0.657 0.343 0.000
R76 Other abnormal immunological findings in serum
0.657 0.343 0.000
M47 Spondylosis
0.656 0.344 0.000
K08 Other disorders of teeth and supporting structures
0.655 0.345 0.000
M62 Other disorders of muscle
0.654 0.345 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.654 0.346 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.654 0.346 0.000
M40-M43 Deforming dorsopathies
0.653 0.347 0.000
O43.9 Placental disorder, unspecified
0.651 0.348 0.000
O43.2 Morbidly adherent placenta
0.651 0.348 0.000
O43.0 Placental transfusion syndromes
0.651 0.348 0.000
Z80.6 Family history of leukaemia
0.651 0.349 0.000
K13 Other diseases of lip and oral mucosa
0.651 0.349 0.000
Z84 Family history of other conditions
0.650 0.349 0.000
Z81 Family history of mental and behavioural disorders
0.650 0.349 0.000
M80 Osteoporosis with pathological fracture
0.650 0.350 0.000
R59.0 Localised enlarged lymph nodes
0.650 0.350 0.000
C84.4 Peripheral T-cell lymphoma
0.649 0.351 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.649 0.351 0.000
O46.0 Antepartum haemorrhage with coagulation defect
0.648 0.351 0.000
H65.2 Chronic serous otitis media
0.648 0.352 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.648 0.352 0.000
K56.7 Ileus, unspecified
0.648 0.352 0.000
M14 Arthropathies in other diseases classified elsewhere
0.647 0.352 0.000
M12 Other specific arthropathies
0.647 0.352 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.647 0.352 0.000
M08 Juvenile arthritis
0.647 0.352 0.000
Q50-Q56 Congenital malformations of genital organs
0.647 0.353 0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother
0.647 0.353 0.000
M79.7 Fibromyalgia
0.645 0.355 0.000
M05 Seropositive rheumatoid arthritis
0.645 0.355 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.644 0.356 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.644 0.356 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.644 0.356 0.000
F99 Mental disorder, not otherwise specified
0.643 0.356 0.000
M89.9 Disorder of bone, unspecified
0.643 0.357 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.643 0.357 0.000
R63.2 Polyphagia
0.643 0.357 0.000
F80-F89 Disorders of psychological development
0.643 0.357 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.641 0.359 0.000
Q35-Q37 Cleft lip and cleft palate
0.641 0.359 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.641 0.359 0.000
Z91.5 Personal history of self-harm
0.641 0.359 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.640 0.360 0.000
K11 Diseases of salivary glands
0.640 0.360 0.000
M10.4 Other secondary gout
0.640 0.360 0.000
M10.3 Gout due to impairment of renal function
0.640 0.360 0.000
M10.2 Drug-induced gout
0.640 0.360 0.000
M10.1 Lead-induced gout
0.640 0.360 0.000
M10.0 Idiopathic gout
0.640 0.360 0.000
H65.1 Other acute nonsuppurative otitis media
0.640 0.360 0.000
H65.0 Acute serous otitis media
0.640 0.360 0.000
K70.4 Alcoholic hepatic failure
0.639 0.361 0.000
K59.9 Functional intestinal disorder, unspecified
0.639 0.361 0.000
M11 Other crystal arthropathies
0.638 0.362 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.638 0.362 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.638 0.362 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.636 0.364 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.636 0.364 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.636 0.364 0.000
B65-B83 Helminthiases
0.636 0.364 0.000
B50-B64 Protozoal diseases
0.636 0.364 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.636 0.364 0.000
A75-A79 Rickettsioses
0.636 0.364 0.000
A70-A74 Other diseases caused by chlamydiae
0.636 0.364 0.000
A20-A28 Certain zoonotic bacterial diseases
0.636 0.364 0.000
A15-A19 Tuberculosis
0.636 0.364 0.000
H69.0 Patulous Eustachian tube
0.635 0.364 0.000
C26.0 Intestinal tract, part unspecified
0.635 0.365 0.000
M10.98 Gout, unspecified (Other)
0.634 0.366 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.634 0.366 0.000
M10.94 Gout, unspecified (Hand)
0.634 0.366 0.000
M10.93 Gout, unspecified (Forearm)
0.634 0.366 0.000
M10.92 Gout, unspecified (Upper arm)
0.634 0.366 0.000
M10.91 Gout, unspecified (Shoulder region)
0.634 0.366 0.000
M10.90 Gout, unspecified (Multiple sites)
0.634 0.366 0.000
Z83.3 Family history of diabetes mellitus
0.633 0.367 0.000
H74.0 Tympanosclerosis
0.633 0.367 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.633 0.367 0.000
R57.2 Septic shock
0.632 0.368 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.631 0.369 0.000
M84.0 Malunion of fracture
0.631 0.369 0.000
C07 Malignant neoplasm of parotid gland
0.631 0.369 0.000
K70.9 Alcoholic liver disease, unspecified
0.630 0.370 0.000
O26.8 Other specified pregnancy-related conditions
0.630 0.370 0.000
M00 Pyogenic arthritis
0.628 0.371 0.000
F32.0 Mild depressive episode
0.628 0.372 0.000
C50 Malignant neoplasm of breast
0.628 0.372 0.000
O24.4 Diabetes mellitus arising in pregnancy
0.627 0.373 0.000
M47.9 Spondylosis, unspecified
0.626 0.374 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.625 0.375 0.000
M35 Other systemic involvement of connective tissue
0.625 0.375 0.000
O23.5 Infections of the genital tract in pregnancy
0.624 0.376 0.000
A80-A89 Viral infections of the central nervous system
0.624 0.376 0.000
Z97.4 Presence of external hearing-aid
0.623 0.377 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.623 0.377 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.623 0.377 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.623 0.377 0.000
G00 Bacterial meningitis, not elsewhere classified
0.623 0.377 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.623 0.377 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.623 0.377 0.000
D05 Carcinoma in situ of breast
0.623 0.377 0.000
F34.1 Dysthymia
0.623 0.377 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.622 0.378 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.622 0.378 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.622 0.378 0.000
O47 False labour
0.621 0.379 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.621 0.379 0.000
S10-S19 Injuries to the neck
0.619 0.381 0.000
M79.68 Pain in limb (Other)
0.619 0.381 0.000
M79.61 Pain in limb (Shoulder region)
0.619 0.381 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.619 0.381 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.618 0.382 0.000
C71.3 Parietal lobe
0.618 0.382 0.000
M24 Other specific joint derangements
0.616 0.384 0.000
B99-B99 Other infectious diseases
0.615 0.385 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.615 0.385 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.615 0.385 0.000
M83 Adult osteomalacia
0.615 0.385 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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