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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80213544
log Bayes Factor = 10.5045
Chromosome 16   position 75,116,252  (GRCh37) Explore rs80213544 on Ensembl!
Variant rs80213544 is part of Cluster X0060

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.998 0.002 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.997 0.003 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.997 0.003 0.000
I25.2 Old myocardial infarction
0.995 0.005 0.000
G56 Mononeuropathies of upper limb
0.995 0.005 0.000
G56.0 Carpal tunnel syndrome
0.994 0.006 0.000
G40-G47 Episodic and paroxysmal disorders
0.993 0.007 0.000
G47 Sleep disorders
0.992 0.008 0.000
G47.3 Sleep apnoea
0.988 0.012 0.000
J30-J39 Other diseases of upper respiratory tract
0.986 0.014 0.000
Chapter X Diseases of the respiratory system
0.986 0.014 0.000
J34 Other disorders of nose and nasal sinuses
0.984 0.016 0.000
I21 Acute myocardial infarction
0.982 0.018 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.980 0.020 0.000
S80-S89 Injuries to the knee and lower leg
0.979 0.021 0.000
Chapter XX External causes of morbidity and mortality
0.979 0.021 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.977 0.023 0.000
I60-I69 Cerebrovascular diseases
0.976 0.024 0.000
I05-I09 Chronic rheumatic heart diseases
0.974 0.026 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.968 0.032 0.000
S82 Fracture of lower leg, including ankle
0.968 0.032 0.000
I71 Aortic aneurysm and dissection
0.963 0.037 0.000
Chapter VIII Diseases of the ear and mastoid process
0.961 0.039 0.000
I72 Other aneurysm
0.957 0.043 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.954 0.046 0.000
I08 Multiple valve diseases
0.954 0.046 0.000
I77 Other disorders of arteries and arterioles
0.943 0.057 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.940 0.060 0.000
I67 Other cerebrovascular diseases
0.939 0.061 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.937 0.063 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.930 0.070 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.928 0.072 0.000
I67.9 Cerebrovascular disease, unspecified
0.927 0.073 0.000
I69 Sequelae of cerebrovascular disease
0.920 0.080 0.000
Chapter V Mental and behavioural disorders
0.918 0.082 0.000
V40-V49 Car occupant injured in transport accident
0.913 0.087 0.000
S82.6 Fracture of lateral malleolus
0.911 0.089 0.000
H65-H75 Diseases of middle ear and mastoid
0.909 0.091 0.000
I10-I15 Hypertensive diseases
0.906 0.094 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.906 0.094 0.000
S82.3 Fracture of lower end of tibia
0.903 0.097 0.000
G30-G32 Other degenerative diseases of the nervous system
0.892 0.108 0.000
J34.3 Hypertrophy of nasal turbinates
0.890 0.110 0.000
G20-G26 Extrapyramidal and movement disorders
0.890 0.110 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.889 0.111 0.000
I72.4 Aneurysm of artery of lower extremity
0.887 0.113 0.000
S82.2 Fracture of shaft of tibia
0.885 0.115 0.000
G58 Other mononeuropathies
0.884 0.116 0.000
J09-J18 Influenza and pneumonia
0.881 0.119 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.880 0.120 0.000
G90-G99 Other disorders of the nervous system
0.876 0.124 0.000
J34.2 Deviated nasal septum
0.873 0.127 0.000
I10 Essential (primary) hypertension
0.873 0.127 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.872 0.128 0.000
S82.60 Fracture of lateral malleolus (closed)
0.870 0.130 0.000
I74 Arterial embolism and thrombosis
0.870 0.130 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.869 0.131 0.000
S10-S19 Injuries to the neck
0.865 0.135 0.000
S50-S59 Injuries to the elbow and forearm
0.860 0.140 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.859 0.141 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.855 0.145 0.000
J33 Nasal polyp
0.855 0.145 0.000
J32 Chronic sinusitis
0.854 0.146 0.000
V80-V89 Other land transport accidents
0.854 0.146 0.000
I61 Intracerebral haemorrhage
0.852 0.148 0.000
S82.30 Fracture of lower end of tibia (closed)
0.846 0.154 0.000
G56.8 Other mononeuropathies of upper limb
0.841 0.159 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.840 0.160 0.000
G56.1 Other lesions of median nerve
0.836 0.164 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.836 0.164 0.000
S80 Superficial injury of lower leg
0.832 0.168 0.000
G47.9 Sleep disorder, unspecified
0.828 0.172 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.826 0.174 0.000
G30 Alzheimer's disease
0.825 0.175 0.000
G82 Paraplegia and tetraplegia
0.825 0.175 0.000
G81 Hemiplegia
0.824 0.176 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.820 0.180 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.820 0.180 0.000
I72.3 Aneurysm of iliac artery
0.820 0.180 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.817 0.183 0.000
T21 Burn and corrosion of trunk
0.816 0.184 0.000
G25 Other extrapyramidal and movement disorders
0.813 0.187 0.000
X60-X84 Intentional self-harm
0.812 0.188 0.000
G41 Status epilepticus
0.811 0.189 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.811 0.189 0.000
H90-H95 Other disorders of ear
0.809 0.191 0.000
F01 Vascular dementia
0.808 0.192 0.000
I77.1 Stricture of artery
0.805 0.194 0.000
S50 Superficial injury of forearm
0.805 0.195 0.000
I05 Rheumatic mitral valve diseases
0.803 0.197 0.000
G91 Hydrocephalus
0.803 0.197 0.000
S83.2 Tear of meniscus, current
0.803 0.197 0.000
I70 Atherosclerosis
0.802 0.197 0.000
S82.21 Fracture of shaft of tibia (open)
0.802 0.198 0.000
J14 Pneumonia due to Haemophilus influenzae
0.797 0.203 0.000
I71.0 Dissection of aorta [any part]
0.796 0.204 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.794 0.206 0.000
J20-J22 Other acute lower respiratory infections
0.793 0.207 0.000
F00 Dementia in Alzheimer's disease
0.792 0.208 0.000
I77.8 Other specified disorders of arteries and arterioles
0.792 0.208 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.788 0.211 0.000
S70-S79 Injuries to the hip and thigh
0.784 0.216 0.000
F03 Unspecified dementia
0.784 0.216 0.000
S82.1 Fracture of upper end of tibia
0.783 0.217 0.000
J95-J99 Other diseases of the respiratory system
0.782 0.218 0.000
T66-T78 Other and unspecified effects of external causes
0.782 0.218 0.000
Chapter XXII Codes for special purposes
0.781 0.219 0.000
T23 Burn and corrosion of wrist and hand
0.778 0.222 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.777 0.223 0.000
H90 Conductive and sensorineural hearing loss
0.774 0.226 0.000
H66 Suppurative and unspecified otitis media
0.773 0.227 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.772 0.228 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.770 0.230 0.000
I69.3 Sequelae of cerebral infarction
0.769 0.231 0.000
V98-V99 Other and unspecified transport accidents
0.768 0.232 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.767 0.233 0.000
J39 Other diseases of upper respiratory tract
0.766 0.234 0.000
J37 Chronic laryngitis and laryngotracheitis
0.766 0.234 0.000
S83.7 Injury to multiple structures of knee
0.761 0.239 0.000
G30.9 Alzheimer's disease, unspecified
0.760 0.240 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.759 0.241 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.758 0.242 0.000
G58.8 Other specified mononeuropathies
0.757 0.243 0.000
H74 Other disorders of middle ear and mastoid
0.757 0.243 0.000
H70 Mastoiditis and related conditions
0.757 0.243 0.000
J33.9 Nasal polyp, unspecified
0.756 0.244 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.754 0.246 0.000
I24 Other acute ischaemic heart diseases
0.752 0.248 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.748 0.252 0.000
G47.8 Other sleep disorders
0.748 0.252 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.746 0.254 0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.744 0.256 0.000
J11 Influenza, virus not identified
0.744 0.256 0.000
G82.2 Paraplegia, unspecified
0.744 0.256 0.000
G81.9 Hemiplegia, unspecified
0.742 0.258 0.000
G80 Infantile cerebral palsy
0.741 0.259 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.740 0.260 0.000
H65 Nonsuppurative otitis media
0.740 0.260 0.000
S50.9 Superficial injury of forearm, unspecified
0.740 0.260 0.000
I23 Certain current complications following acute myocardial infarction
0.739 0.261 0.000
S89 Other and unspecified injuries of lower leg
0.739 0.261 0.000
F01.9 Vascular dementia, unspecified
0.739 0.261 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.738 0.262 0.000
W50-W64 Exposure to animate mechanical forces
0.738 0.262 0.000
G57 Mononeuropathies of lower limb
0.737 0.263 0.000
I08.0 Disorders of both mitral and aortic valves
0.736 0.264 0.000
G54 Nerve root and plexus disorders
0.735 0.265 0.000
J32.1 Chronic frontal sinusitis
0.734 0.266 0.000
G51 Facial nerve disorders
0.734 0.266 0.000
F02 Dementia in other diseases classified elsewhere
0.734 0.266 0.000
G20 Parkinson's disease
0.733 0.267 0.000
V48 Car occupant injured in noncollision transport accident
0.733 0.267 0.000
H73 Other disorders of tympanic membrane
0.733 0.267 0.000
F60-F69 Disorders of adult personality and behaviour
0.732 0.268 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.732 0.268 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.730 0.270 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.729 0.271 0.000
X20-X29 Contact with venomous animals and plants
0.729 0.271 0.000
I72.8 Aneurysm of other specified arteries
0.728 0.272 0.000
I74.5 Embolism and thrombosis of iliac artery
0.726 0.274 0.000
I77.0 Arteriovenous fistula, acquired
0.722 0.278 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.721 0.279 0.000
I08.8 Other multiple valve diseases
0.721 0.279 0.000
V44 Car occupant injured in collision with heavy transport vehicle or bus
0.718 0.282 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.718 0.282 0.000
G91.9 Hydrocephalus, unspecified
0.718 0.282 0.000
I25.5 Ischaemic cardiomyopathy
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
V10-V19 Pedal cyclist injured in transport accident
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.717 0.283 0.000
G96 Other disorders of central nervous system
0.716 0.284 0.000
Y48 Anaesthetics and therapeutic gases
0.715 0.285 0.000
G47.4 Narcolepsy and cataplexy
0.715 0.285 0.000
G52 Disorders of other cranial nerves
0.715 0.285 0.000
H60-H62 Diseases of external ear
0.714 0.286 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.714 0.286 0.000
G56.4 Causalgia
0.714 0.286 0.000
G56.3 Lesion of radial nerve
0.714 0.286 0.000
G25.0 Essential tremor
0.713 0.287 0.000
F99-F99 Unspecified mental disorder
0.713 0.287 0.000
V49.9 Car occupant [any] injured in unspecified traffic accident
0.713 0.287 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.712 0.288 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.712 0.288 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.712 0.288 0.000
G47.2 Disorders of the sleep-wake schedule
0.711 0.288 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
F70-F79 Mental retardation
0.709 0.291 0.000
Y52 Agents primarily affecting the cardiovascular system
0.708 0.292 0.000
H90.3 Sensorineural hearing loss, bilateral
0.707 0.293 0.000
T31 Burns classified according to extent of body surface involved
0.706 0.294 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.706 0.294 0.000
I24.8 Other forms of acute ischaemic heart disease
0.705 0.294 0.000
T20 Burn and corrosion of head and neck
0.705 0.295 0.000
J30 Vasomotor and allergic rhinitis
0.704 0.296 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.704 0.296 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.704 0.296 0.000
T33-T35 Frostbite
0.703 0.297 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.703 0.297 0.000
T00-T07 Injuries involving multiple body regions
0.703 0.297 0.000
S82.20 Fracture of shaft of tibia (closed)
0.702 0.298 0.000
S88 Traumatic amputation of lower leg
0.702 0.298 0.000
S87 Crushing injury of lower leg
0.702 0.298 0.000
S85 Injury of blood vessels at lower leg level
0.702 0.298 0.000
S84 Injury of nerves at lower leg level
0.702 0.298 0.000
Y35-Y36 Legal intervention and operations of war
0.702 0.298 0.000
Y10-Y34 Event of undetermined intent
0.702 0.298 0.000
Y00-Y09 Assault
0.702 0.298 0.000
X85-X99 Assault
0.702 0.298 0.000
X30-X39 Exposure to forces of nature
0.702 0.298 0.000
X00-X09 Exposure to smoke, fire and flames
0.702 0.298 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.702 0.298 0.000
W75-W84 Other accidental threats to breathing
0.702 0.298 0.000
W65-W74 Accidental drowning and submersion
0.702 0.298 0.000
V95-V97 Air and space transport accidents
0.702 0.298 0.000
V90-V94 Water transport accidents
0.702 0.298 0.000
V70-V79 Bus occupant injured in transport accident
0.702 0.298 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.702 0.298 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.702 0.298 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.702 0.298 0.000
V01-V09 Pedestrian injured in transport accident
0.702 0.298 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.700 0.300 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.700 0.300 0.000
S86 Injury of muscle and tendon at lower leg level
0.699 0.301 0.000
I09 Other rheumatic heart diseases
0.699 0.301 0.000
I06 Rheumatic aortic valve diseases
0.699 0.301 0.000
I20 Angina pectoris
0.698 0.302 0.000
H66.3 Other chronic suppurative otitis media
0.697 0.303 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.697 0.303 0.000
X10-X19 Contact with heat and hot substances
0.697 0.303 0.000
I77.6 Arteritis, unspecified
0.697 0.303 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.696 0.304 0.000
S19 Other and unspecified injuries of neck
0.696 0.304 0.000
G58.9 Mononeuropathy, unspecified
0.695 0.305 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.694 0.306 0.000
S82.9 Fracture of lower leg, part unspecified
0.694 0.306 0.000
S82.7 Multiple fractures of lower leg
0.694 0.306 0.000
S82.31 Fracture of lower end of tibia (open)
0.693 0.307 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.692 0.308 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.692 0.308 0.000
H90.5 Sensorineural hearing loss, unspecified
0.691 0.309 0.000
J38.7 Other diseases of larynx
0.691 0.309 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.690 0.309 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.690 0.309 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.690 0.309 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.690 0.309 0.000
H69 Other disorders of Eustachian tube
0.690 0.310 0.000
T21.2 Burn of second degree of trunk
0.690 0.310 0.000
V43 Car occupant injured in collision with car, pick-up truck or van
0.690 0.310 0.000
I05.0 Mitral stenosis
0.690 0.310 0.000
I72.0 Aneurysm of carotid artery
0.689 0.311 0.000
V20-V29 Motorcycle rider injured in transport accident
0.688 0.312 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.688 0.312 0.000
G25.3 Myoclonus
0.688 0.312 0.000
J38.3 Other diseases of vocal cords
0.687 0.313 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.687 0.313 0.000
I72.9 Aneurysm of unspecified site
0.686 0.314 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.686 0.314 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.686 0.314 0.000
I72.2 Aneurysm of renal artery
0.686 0.314 0.000
I72.1 Aneurysm of artery of upper extremity
0.686 0.314 0.000
I08.9 Multiple valve disease, unspecified
0.684 0.316 0.000
G43 Migraine
0.684 0.316 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.682 0.318 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.682 0.318 0.000
G41.9 Status epilepticus, unspecified
0.681 0.319 0.000
G50 Disorders of trigeminal nerve
0.679 0.321 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.677 0.323 0.000
I15 Secondary hypertension
0.677 0.323 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.677 0.323 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.677 0.323 0.000
I77.5 Necrosis of artery
0.676 0.323 0.000
I77.4 Coeliac artery compression syndrome
0.676 0.323 0.000
I77.3 Arterial fibromuscular dysplasia
0.676 0.323 0.000
I77.2 Rupture of artery
0.676 0.323 0.000
Y40 Systemic antibiotics
0.676 0.324 0.000
G82.4 Spastic tetraplegia
0.675 0.325 0.000
W20-W49 Exposure to inanimate mechanical forces
0.675 0.325 0.000
G61 Inflammatory polyneuropathy
0.674 0.325 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.673 0.327 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.673 0.327 0.000
I67.5 Moyamoya disease
0.673 0.327 0.000
I67.4 Hypertensive encephalopathy
0.673 0.327 0.000
I67.3 Progressive vascular leukoencephalopathy
0.673 0.327 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.673 0.327 0.000
F80-F89 Disorders of psychological development
0.673 0.327 0.000
H80-H83 Diseases of inner ear
0.673 0.327 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.672 0.328 0.000
S80.8 Other superficial injuries of lower leg
0.672 0.328 0.000
G58.7 Mononeuritis multiplex
0.672 0.328 0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.671 0.328 0.000
S83.3 Tear of articular cartilage of knee, current
0.671 0.328 0.000
S83.1 Dislocation of knee
0.671 0.328 0.000
S83.0 Dislocation of patella
0.671 0.328 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.671 0.329 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.671 0.329 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.671 0.329 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.671 0.329 0.000
Y85 Sequelae of transport accidents
0.670 0.329 0.000
Y59 Other and unspecified vaccines and biological substances
0.670 0.330 0.000
S10 Superficial injury of neck
0.668 0.332 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.668 0.332 0.000
T25 Burn and corrosion of ankle and foot
0.666 0.333 0.000
S82.5 Fracture of medial malleolus
0.664 0.336 0.000
G44 Other headache syndromes
0.664 0.336 0.000
Q80-Q89 Other congenital malformations
0.663 0.337 0.000
J32.4 Chronic pansinusitis
0.662 0.338 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.662 0.338 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.661 0.339 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.660 0.340 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.659 0.340 0.000
J38.6 Stenosis of larynx
0.658 0.341 0.000
V89.9 Person injured in unspecified vehicle accident
0.658 0.342 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.658 0.342 0.000
H65.4 Other chronic nonsuppurative otitis media
0.656 0.344 0.000
S56 Injury of muscle and tendon at forearm level
0.656 0.344 0.000
G30.0 Alzheimer's disease with early onset
0.656 0.344 0.000
J98 Other respiratory disorders
0.656 0.344 0.000
S80.0 Contusion of knee
0.656 0.344 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.655 0.345 0.000
V47 Car occupant injured in collision with fixed or stationary object
0.655 0.345 0.000
V46 Car occupant injured in collision with other nonmotor vehicle
0.655 0.345 0.000
V45 Car occupant injured in collision with railway train or railway vehicle
0.655 0.345 0.000
V42 Car occupant injured in collision with two- or three-wheeled motor vehicle
0.655 0.345 0.000
V41 Car occupant injured in collision with pedal cycle
0.655 0.345 0.000
V40 Car occupant injured in collision with pedestrian or animal
0.655 0.345 0.000
V80 Animal-rider or occupant of animal-drawn vehicle injured in transport accident
0.654 0.346 0.000
F05.9 Delirium, unspecified
0.654 0.346 0.000
S82.61 Fracture of lateral malleolus (open)
0.653 0.347 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.653 0.347 0.000
J38.2 Nodules of vocal cords
0.653 0.347 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.653 0.347 0.000
V49.5 Passenger injured in collision with other and unspecified motor vehicles in traffic accident
0.652 0.348 0.000
Y43 Primarily systemic agents
0.652 0.348 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.651 0.348 0.000
H68 Eustachian salpingitis and obstruction
0.651 0.348 0.000
H67 Otitis media in diseases classified elsewhere
0.651 0.348 0.000
I67.1 Cerebral aneurysm, nonruptured
0.651 0.349 0.000
J22 Unspecified acute lower respiratory infection
0.651 0.349 0.000
I13 Hypertensive heart and renal disease
0.650 0.350 0.000
I20.8 Other forms of angina pectoris
0.650 0.350 0.000
G70-G73 Diseases of myoneural junction and muscle
0.649 0.350 0.000
S50.8 Other superficial injuries of forearm
0.649 0.350 0.000
T66 Unspecified effects of radiation
0.649 0.351 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.649 0.351 0.000
F09 Unspecified organic or symptomatic mental disorder
0.649 0.351 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.649 0.351 0.000
I62 Other nontraumatic intracranial haemorrhage
0.648 0.352 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.647 0.353 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.645 0.355 0.000
J11.1 Influenza with other respiratory manifestations, virus not identified
0.645 0.355 0.000
J32.9 Chronic sinusitis, unspecified
0.643 0.357 0.000
J33.0 Polyp of nasal cavity
0.643 0.357 0.000
W00-W19 Falls
0.642 0.358 0.000
X50-X57 Overexertion, travel and privation
0.642 0.358 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.642 0.358 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.642 0.358 0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified
0.642 0.358 0.000
S54 Injury of nerves at forearm level
0.639 0.360 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.639 0.360 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.638 0.361 0.000
H70.8 Other mastoiditis and related conditions
0.638 0.361 0.000
G23 Other degenerative diseases of basal ganglia
0.638 0.362 0.000
G21 Secondary Parkinsonism
0.638 0.362 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.638 0.362 0.000
G22 Parkinsonism in diseases classified elsewhere
0.638 0.362 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.637 0.363 0.000
J32.0 Chronic maxillary sinusitis
0.636 0.364 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.634 0.366 0.000
G03 Meningitis due to other and unspecified causes
0.634 0.366 0.000
G58.0 Intercostal neuropathy
0.634 0.366 0.000
G83 Other paralytic syndromes
0.633 0.367 0.000
T21.0 Burn of unspecified degree of trunk
0.633 0.367 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.633 0.367 0.000
G00 Bacterial meningitis, not elsewhere classified
0.632 0.367 0.000
I61.8 Other intracerebral haemorrhage
0.632 0.367 0.000
S70 Superficial injury of hip and thigh
0.632 0.368 0.000
J17 Pneumonia in diseases classified elsewhere
0.632 0.368 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.632 0.368 0.000
J12 Viral pneumonia, not elsewhere classified
0.632 0.368 0.000
J09 Influenza due to certain identified influenza virus
0.632 0.368 0.000
S82.11 Fracture of upper end of tibia (open)
0.631 0.369 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.630 0.370 0.000
T21.3 Burn of third degree of trunk
0.629 0.371 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.628 0.372 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.628 0.372 0.000
G92 Toxic encephalopathy
0.628 0.372 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.628 0.372 0.000
G91.1 Obstructive hydrocephalus
0.628 0.372 0.000
T23.3 Burn of third degree of wrist and hand
0.627 0.373 0.000
I05.1 Rheumatic mitral insufficiency
0.627 0.373 0.000
S72 Fracture of femur
0.626 0.374 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.625 0.374 0.000
G60 Hereditary and idiopathic neuropathy
0.625 0.375 0.000
T31.0 Burns involving less than 10% of body surface
0.624 0.376 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.624 0.376 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.624 0.376 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.624 0.376 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.624 0.376 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.624 0.376 0.000
Y85.0 Sequelae of motor-vehicle accident
0.624 0.376 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.623 0.377 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.623 0.377 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.623 0.377 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.623 0.377 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.623 0.377 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.623 0.377 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.623 0.377 0.000
J10 Influenza due to identified influenza virus
0.623 0.377 0.000
G93 Other disorders of brain
0.622 0.378 0.000
G91.2 Normal-pressure hydrocephalus
0.622 0.378 0.000
J60-J70 Lung diseases due to external agents
0.621 0.378 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.621 0.378 0.000
S82.4 Fracture of fibula alone
0.621 0.379 0.000
S17 Crushing injury of neck
0.620 0.380 0.000
S15 Injury of blood vessels at neck level
0.620 0.380 0.000
S14 Injury of nerves and spinal cord at neck level
0.620 0.380 0.000
S11 Open wound of neck
0.620 0.380 0.000
S18 Traumatic amputation at neck level
0.620 0.380 0.000
S16 Injury of muscle and tendon at neck level
0.620 0.380 0.000
T23.2 Burn of second degree of wrist and hand
0.619 0.381 0.000
F40 Phobic anxiety disorders
0.619 0.381 0.000
G96.1 Disorders of meninges, not elsewhere classified
0.619 0.381 0.000
X45 Accidental poisoning by and exposure to alcohol
0.619 0.381 0.000
I61.4 Intracerebral haemorrhage in cerebellum
0.618 0.381 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.618 0.382 0.000
S59 Other and unspecified injuries of forearm
0.617 0.383 0.000
S58 Traumatic amputation of forearm
0.617 0.383 0.000
S57 Crushing injury of forearm
0.617 0.383 0.000
S55 Injury of blood vessels at forearm level
0.617 0.383 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.617 0.383 0.000
V99 Unspecified transport accident
0.617 0.383 0.000
Y44 Agents primarily affecting blood constituents
0.616 0.384 0.000
Y48.2 Other and unspecified general anaesthetics
0.615 0.385 0.000
Y40.9 Systemic antibiotic, unspecified
0.613 0.387 0.000
J39.9 Disease of upper respiratory tract, unspecified
0.613 0.387 0.000
Y58 Bacterial vaccines
0.613 0.387 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.613 0.387 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.613 0.387 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.613 0.387 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.613 0.387 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.613 0.387 0.000
S13.4 Sprain and strain of cervical spine
0.613 0.387 0.000
I74.8 Embolism and thrombosis of other arteries
0.613 0.387 0.000
J33.1 Polypoid sinus degeneration
0.613 0.387 0.000
J32.3 Chronic sphenoidal sinusitis
0.612 0.387 0.000
V88 Nontraffic accident of specified type but victim's mode of transport unknown
0.612 0.388 0.000
V87 Traffic accident of specified type but victim's mode of transport unknown
0.612 0.388 0.000
V86 Occupant of special all-terrain or other motor vehicle designed primarily for off-road use, injured in transport accident
0.612 0.388 0.000
V85 Occupant of special construction vehicle injured in transport accident
0.612 0.388 0.000
V84 Occupant of special vehicle mainly used in agriculture injured in transport accident
0.612 0.388 0.000
V83 Occupant of special vehicle mainly used on industrial premises injured in transport accident
0.612 0.388 0.000
V82 Occupant of streetcar injured in transport accident
0.612 0.388 0.000
V81 Occupant of railway train or railway vehicle injured in transport accident
0.612 0.388 0.000
I97.1 Other functional disturbances following cardiac surgery
0.612 0.388 0.000
G61.0 Guillain-Barre syndrome
0.611 0.388 0.000
J32.2 Chronic ethmoidal sinusitis
0.611 0.389 0.000
I61.6 Intracerebral haemorrhage, multiple localised
0.611 0.389 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.611 0.389 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.610 0.389 0.000
G57.1 Meralgia paraesthetica
0.610 0.390 0.000
F02.3 Dementia in Parkinson's disease
0.610 0.390 0.000
G90 Disorders of autonomic nervous system
0.610 0.390 0.000
F44 Dissociative [conversion] disorders
0.609 0.390 0.000
F64 Gender identity disorders
0.609 0.391 0.000
S40-S49 Injuries to the shoulder and upper arm
0.609 0.391 0.000
J37.0 Chronic laryngitis
0.608 0.391 0.000
S82.8 Fractures of other parts of lower leg
0.606 0.394 0.000
H74.3 Other acquired abnormalities of ear ossicles
0.605 0.395 0.000
J98.1 Pulmonary collapse
0.605 0.395 0.000
V48.4 Person injured while boarding or alighting
0.604 0.396 0.000
G80.1 Spastic diplegia
0.603 0.397 0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot
0.601 0.398 0.000
S50.0 Contusion of elbow
0.601 0.399 0.000
I70.0 Atherosclerosis of aorta
0.600 0.400 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.598 0.402 0.000
J39.8 Other specified diseases of upper respiratory tract
0.598 0.402 0.000
S80.7 Multiple superficial injuries of lower leg
0.597 0.403 0.000
Y57 Other and unspecified drugs and medicaments
0.597 0.403 0.000
G51.0 Bell's palsy
0.597 0.403 0.000
H91 Other hearing loss
0.596 0.404 0.000
J38.5 Laryngeal spasm
0.596 0.404 0.000
I25.3 Aneurysm of heart
0.596 0.404 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.594 0.406 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.594 0.406 0.000
Q82 Other congenital malformations of skin
0.594 0.406 0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck
0.593 0.407 0.000
G30.8 Other Alzheimer's disease
0.592 0.408 0.000
G30.1 Alzheimer's disease with late onset
0.592 0.408 0.000
G82.3 Flaccid tetraplegia
0.591 0.409 0.000
G82.0 Flaccid paraplegia
0.591 0.409 0.000
I11 Hypertensive heart disease
0.591 0.409 0.000
G81.1 Spastic hemiplegia
0.591 0.409 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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