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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs80301223
log Bayes Factor = 12.0195
Chromosome 8   position 119,648,160  (GRCh37) Explore rs80301223 on Ensembl!
Variant rs80301223 is part of Cluster X0019

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.999 0.001 0.000
K22 Other diseases of oesophagus
0.999 0.001 0.000
J44 Other chronic obstructive pulmonary disease
0.999 0.001 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.996 0.004 0.000
Chapter XI Diseases of the digestive system
0.996 0.004 0.000
K22.1 Ulcer of oesophagus
0.993 0.007 0.000
M70-M79 Other soft tissue disorders
0.984 0.016 0.000
O60-O75 Complications of labour and delivery
0.982 0.018 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.982 0.018 0.000
M80-M85 Disorders of bone density and structure
0.979 0.021 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.979 0.021 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.976 0.024 0.000
E65-E68 Obesity and other hyperalimentation
0.970 0.030 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.969 0.031 0.000
K22.9 Disease of oesophagus, unspecified
0.965 0.035 0.000
K22.2 Oesophageal obstruction
0.964 0.036 0.000
M75 Shoulder lesions
0.964 0.036 0.000
E66 Obesity
0.963 0.037 0.000
M20-M25 Other joint disorders
0.962 0.038 0.000
E66.8 Other obesity
0.956 0.044 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.953 0.047 0.000
Chapter XX External causes of morbidity and mortality
0.953 0.047 0.000
J00-J06 Acute upper respiratory infections
0.953 0.047 0.000
O63 Long labour
0.952 0.048 0.000
K20 Oesophagitis
0.946 0.054 0.000
M81 Osteoporosis without pathological fracture
0.941 0.059 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.941 0.059 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.940 0.060 0.000
M75.1 Rotator cuff syndrome
0.934 0.066 0.000
J95-J99 Other diseases of the respiratory system
0.930 0.070 0.000
K70-K77 Diseases of liver
0.924 0.076 0.000
M25 Other joint disorders, not elsewhere classified
0.922 0.078 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.919 0.081 0.000
K35-K38 Diseases of appendix
0.917 0.083 0.000
Chapter VI Diseases of the nervous system
0.916 0.084 0.000
J60-J70 Lung diseases due to external agents
0.916 0.084 0.000
J03 Acute tonsillitis
0.916 0.084 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.912 0.088 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.903 0.097 0.000
O00-O08 Pregnancy with abortive outcome
0.900 0.100 0.000
J09-J18 Influenza and pneumonia
0.898 0.102 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.895 0.105 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.894 0.106 0.000
J03.9 Acute tonsillitis, unspecified
0.889 0.111 0.000
M24 Other specific joint derangements
0.882 0.117 0.000
K35 Acute appendicitis
0.882 0.118 0.000
Chapter VIII Diseases of the ear and mastoid process
0.879 0.121 0.000
S70-S79 Injuries to the hip and thigh
0.876 0.124 0.000
O63.0 Prolonged first stage (of labour)
0.873 0.127 0.000
E00-E07 Disorders of thyroid gland
0.873 0.127 0.000
M81.9 Osteoporosis, unspecified
0.870 0.130 0.000
Chapter IX Diseases of the circulatory system
0.870 0.130 0.000
M25.5 Pain in joint
0.866 0.134 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.864 0.136 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.861 0.139 0.000
Chapter I Certain infectious and parasitic diseases
0.853 0.147 0.000
J30-J39 Other diseases of upper respiratory tract
0.851 0.149 0.000
I27 Other pulmonary heart diseases
0.849 0.151 0.000
K22.4 Dyskinesia of oesophagus
0.849 0.151 0.000
S90-S99 Injuries to the ankle and foot
0.848 0.152 0.000
K70 Alcoholic liver disease
0.846 0.154 0.000
O63.1 Prolonged second stage (of labour)
0.843 0.157 0.000
H65-H75 Diseases of middle ear and mastoid
0.842 0.158 0.000
M81.4 Drug-induced osteoporosis
0.840 0.160 0.000
J98 Other respiratory disorders
0.839 0.161 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.837 0.163 0.000
E04 Other non-toxic goitre
0.834 0.166 0.000
M25.51 Pain in joint (Shoulder region)
0.833 0.167 0.000
J18 Pneumonia, organism unspecified
0.830 0.170 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.826 0.174 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.825 0.175 0.000
M25.57 Pain in joint (Ankle and foot)
0.822 0.178 0.000
I27.0 Primary pulmonary hypertension
0.817 0.183 0.000
M75.3 Calcific tendinitis of shoulder
0.816 0.184 0.000
J43 Emphysema
0.814 0.186 0.000
O62 Abnormalities of forces of labour
0.814 0.186 0.000
M31 Other necrotising vasculopathies
0.812 0.188 0.000
J69 Pneumonitis due to solids and liquids
0.811 0.189 0.000
M50-M54 Other dorsopathies
0.811 0.189 0.000
M84 Disorders of continuity of bone
0.811 0.189 0.000
K22.8 Other specified diseases of oesophagus
0.804 0.196 0.000
G40-G47 Episodic and paroxysmal disorders
0.802 0.198 0.000
K22.0 Achalasia of cardia
0.802 0.198 0.000
E04.9 Non-toxic goitre, unspecified
0.802 0.198 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.800 0.200 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.800 0.200 0.000
M75.4 Impingement syndrome of shoulder
0.798 0.202 0.000
O72 Postpartum haemorrhage
0.795 0.205 0.000
Y95 Nosocomial condition
0.795 0.205 0.000
M75.5 Bursitis of shoulder
0.794 0.205 0.000
D68 Other coagulation defects
0.794 0.206 0.000
M25.8 Other specified joint disorders
0.792 0.208 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.792 0.208 0.000
K35.2 Acute appendicitis with generalized peritonitis
0.790 0.210 0.000
T92 Sequelae of injuries of upper limb
0.789 0.211 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.788 0.212 0.000
J45 Asthma
0.787 0.213 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.786 0.214 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.786 0.214 0.000
M72 Fibroblastic disorders
0.783 0.217 0.000
O66 Other obstructed labour
0.783 0.217 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.781 0.219 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.779 0.221 0.000
S80-S89 Injuries to the knee and lower leg
0.779 0.221 0.000
Q80-Q89 Other congenital malformations
0.778 0.222 0.000
W00-W19 Falls
0.777 0.223 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.777 0.223 0.000
M51 Other intervertebral disk disorders
0.777 0.223 0.000
K22.7 Barrett's oesophagus
0.777 0.223 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.775 0.225 0.000
E50-E64 Other nutritional deficiencies
0.775 0.225 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.775 0.225 0.000
J42 Unspecified chronic bronchitis
0.773 0.227 0.000
O63.9 Long labour, unspecified
0.773 0.227 0.000
H73 Other disorders of tympanic membrane
0.772 0.228 0.000
G57 Mononeuropathies of lower limb
0.771 0.229 0.000
E66.9 Obesity, unspecified
0.770 0.230 0.000
O00 Ectopic pregnancy
0.770 0.230 0.000
S72 Fracture of femur
0.770 0.230 0.000
M91-M94 Chondropathies
0.769 0.231 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.768 0.232 0.000
H74 Other disorders of middle ear and mastoid
0.767 0.233 0.000
M81.40 Drug-induced osteoporosis (Multiple sites)
0.767 0.233 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.766 0.234 0.000
Y00-Y09 Assault
0.765 0.235 0.000
M85 Other disorders of bone density and structure
0.764 0.236 0.000
O03 Spontaneous abortion
0.764 0.236 0.000
M75.9 Shoulder lesion, unspecified
0.763 0.237 0.000
O30 Multiple gestation
0.763 0.237 0.000
K27 Peptic ulcer, site unspecified
0.763 0.237 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.762 0.238 0.000
O34.1 Maternal care for tumour of corpus uteri
0.761 0.239 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.759 0.240 0.000
M20 Acquired deformities of fingers and toes
0.758 0.242 0.000
K25 Gastric ulcer
0.756 0.244 0.000
K31 Other diseases of stomach and duodenum
0.755 0.245 0.000
I26 Pulmonary embolism
0.755 0.245 0.000
K35.8 Acute appendicitis, other and unspecified
0.751 0.249 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.750 0.250 0.000
J18.9 Pneumonia, unspecified
0.750 0.250 0.000
M71 Other bursopathies
0.750 0.250 0.000
O34.4 Maternal care for other abnormalities of cervix
0.745 0.255 0.000
K74 Fibrosis and cirrhosis of liver
0.744 0.256 0.000
I27.2 Other secondary pulmonary hypertension
0.743 0.257 0.000
M40-M43 Deforming dorsopathies
0.742 0.258 0.000
M24.1 Other articular cartilage disorders
0.741 0.259 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.740 0.260 0.000
J98.1 Pulmonary collapse
0.740 0.260 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.739 0.261 0.000
G47 Sleep disorders
0.739 0.261 0.000
M82 Osteoporosis in diseases classified elsewhere
0.738 0.262 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.738 0.262 0.000
M60-M63 Disorders of muscles
0.737 0.263 0.000
J45.0 Predominantly allergic asthma
0.737 0.263 0.000
J69.0 Pneumonitis due to food and vomit
0.736 0.264 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.736 0.264 0.000
K75 Other inflammatory liver diseases
0.735 0.265 0.000
S70 Superficial injury of hip and thigh
0.734 0.266 0.000
M65-M68 Disorders of synovium and tendon
0.734 0.266 0.000
M21 Other acquired deformities of limbs
0.734 0.266 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.733 0.267 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.733 0.267 0.000
B35-B49 Mycoses
0.733 0.267 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.732 0.268 0.000
M24.0 Loose body in joint
0.731 0.269 0.000
M25.9 Joint disorder, unspecified
0.730 0.270 0.000
G30-G32 Other degenerative diseases of the nervous system
0.730 0.270 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.729 0.271 0.000
B25-B34 Other viral diseases
0.728 0.272 0.000
M80 Osteoporosis with pathological fracture
0.727 0.272 0.000
V80-V89 Other land transport accidents
0.726 0.274 0.000
O03.9 Complete or unspecified, without complication
0.726 0.274 0.000
K22.5 Diverticulum of oesophagus, acquired
0.725 0.275 0.000
S10-S19 Injuries to the neck
0.725 0.275 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.725 0.275 0.000
E07 Other disorders of thyroid
0.725 0.275 0.000
K50-K52 Noninfective enteritis and colitis
0.725 0.275 0.000
J01 Acute sinusitis
0.724 0.276 0.000
D73 Diseases of spleen
0.723 0.277 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.723 0.277 0.000
H73.8 Other specified disorders of tympanic membrane
0.722 0.278 0.000
I30-I52 Other forms of heart disease
0.721 0.279 0.000
J00 Acute nasopharyngitis [common cold]
0.720 0.280 0.000
K70.9 Alcoholic liver disease, unspecified
0.719 0.281 0.000
K26 Duodenal ulcer
0.718 0.282 0.000
T66-T78 Other and unspecified effects of external causes
0.717 0.283 0.000
S60-S69 Injuries to the wrist and hand
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.284 0.000
K35.3 Acute appendicitis with localized peritonitis
0.716 0.284 0.000
K22.3 Perforation of oesophagus
0.716 0.284 0.000
K72 Hepatic failure, not elsewhere classified
0.715 0.285 0.000
K70.0 Alcoholic fatty liver
0.715 0.285 0.000
K28 Gastrojejunal ulcer
0.714 0.286 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.714 0.286 0.000
S20-S29 Injuries to the thorax
0.714 0.286 0.000
O16 Unspecified maternal hypertension
0.714 0.286 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.714 0.286 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.713 0.287 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.712 0.287 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.711 0.289 0.000
D55-D59 Haemolytic anaemias
0.710 0.290 0.000
M25.0 Haemarthrosis
0.710 0.290 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.709 0.291 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.709 0.291 0.000
S92 Fracture of foot, except ankle
0.708 0.291 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.708 0.292 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.706 0.294 0.000
T93 Sequelae of injuries of lower limb
0.706 0.294 0.000
M76 Enthesopathies of lower limb, excluding foot
0.705 0.295 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.705 0.295 0.000
J40 Bronchitis, not specified as acute or chronic
0.705 0.295 0.000
O74 Complications of anaesthesia during labour and delivery
0.704 0.296 0.000
O71 Other obstetric trauma
0.704 0.296 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.704 0.296 0.000
O61 Failed induction of labour
0.704 0.296 0.000
O60 Preterm delivery
0.704 0.296 0.000
M83 Adult osteomalacia
0.702 0.298 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.701 0.299 0.000
T33-T35 Frostbite
0.700 0.300 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.700 0.300 0.000
T00-T07 Injuries involving multiple body regions
0.700 0.300 0.000
D68.8 Other specified coagulation defects
0.699 0.300 0.000
K70.3 Alcoholic cirrhosis of liver
0.699 0.301 0.000
K73 Chronic hepatitis, not elsewhere classified
0.699 0.301 0.000
S90 Superficial injury of ankle and foot
0.699 0.301 0.000
G57.6 Lesion of plantar nerve
0.698 0.302 0.000
W50-W64 Exposure to animate mechanical forces
0.697 0.302 0.000
X20-X29 Contact with venomous animals and plants
0.697 0.302 0.000
G47.3 Sleep apnoea
0.697 0.303 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.697 0.303 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.696 0.304 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.696 0.304 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.696 0.304 0.000
M51.9 Intervertebral disk disorder, unspecified
0.695 0.305 0.000
E67 Other hyperalimentation
0.695 0.305 0.000
E68 Sequelae of hyperalimentation
0.695 0.305 0.000
E65 Localised adiposity
0.695 0.305 0.000
D73.0 Hyposplenism
0.694 0.306 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.694 0.306 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.693 0.306 0.000
E04.0 Non-toxic diffuse goitre
0.693 0.307 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.693 0.307 0.000
M75.8 Other shoulder lesions
0.691 0.309 0.000
O62.2 Other uterine inertia
0.690 0.310 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.690 0.310 0.000
E66.1 Drug-induced obesity
0.690 0.310 0.000
E66.0 Obesity due to excess calories
0.690 0.310 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.690 0.310 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.690 0.310 0.000
M34 Systemic sclerosis
0.690 0.310 0.000
M33 Dermatopolymyositis
0.690 0.310 0.000
M32 Systemic lupus erythematosus
0.690 0.310 0.000
M30 Polyarteritis nodosa and related conditions
0.690 0.310 0.000
K50 Crohn's disease [regional enteritis]
0.690 0.310 0.000
K35.9 Acute appendicitis, unspecified
0.689 0.311 0.000
E70-E90 Metabolic disorders
0.688 0.312 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.687 0.313 0.000
Y40 Systemic antibiotics
0.687 0.313 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.686 0.314 0.000
D68.9 Coagulation defect, unspecified
0.686 0.314 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.686 0.314 0.000
O40 Polyhydramnios
0.685 0.314 0.000
O44 Placenta praevia
0.685 0.315 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.685 0.315 0.000
O45 Premature separation of placenta [abruptio placentae]
0.684 0.316 0.000
O43 Placental disorders
0.684 0.316 0.000
O33 Maternal care for known or suspected disproportion
0.684 0.316 0.000
O31 Complications specific to multiple gestation
0.684 0.316 0.000
Y35-Y36 Legal intervention and operations of war
0.683 0.317 0.000
Y10-Y34 Event of undetermined intent
0.683 0.317 0.000
X85-X99 Assault
0.683 0.317 0.000
X50-X57 Overexertion, travel and privation
0.683 0.317 0.000
X30-X39 Exposure to forces of nature
0.683 0.317 0.000
X10-X19 Contact with heat and hot substances
0.683 0.317 0.000
X00-X09 Exposure to smoke, fire and flames
0.683 0.317 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.683 0.317 0.000
W75-W84 Other accidental threats to breathing
0.683 0.317 0.000
W65-W74 Accidental drowning and submersion
0.683 0.317 0.000
V98-V99 Other and unspecified transport accidents
0.683 0.317 0.000
V95-V97 Air and space transport accidents
0.683 0.317 0.000
V90-V94 Water transport accidents
0.683 0.317 0.000
V70-V79 Bus occupant injured in transport accident
0.683 0.317 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.683 0.317 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.683 0.317 0.000
V40-V49 Car occupant injured in transport accident
0.683 0.317 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.683 0.317 0.000
V01-V09 Pedestrian injured in transport accident
0.683 0.317 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.683 0.317 0.000
J04 Acute laryngitis and tracheitis
0.683 0.317 0.000
M51.2 Other specified intervertebral disk displacement
0.683 0.317 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.683 0.317 0.000
J34 Other disorders of nose and nasal sinuses
0.683 0.317 0.000
O41 Other disorders of amniotic fluid and membranes
0.682 0.318 0.000
T90 Sequelae of injuries of head
0.681 0.319 0.000
I28 Other diseases of pulmonary vessels
0.680 0.319 0.000
B15-B19 Viral hepatitis
0.680 0.320 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.680 0.320 0.000
T63 Toxic effect of contact with venomous animals
0.680 0.320 0.000
M25.3 Other instability of joint
0.680 0.320 0.000
T79-T79 Certain early complications of trauma
0.679 0.321 0.000
H72 Perforation of tympanic membrane
0.678 0.322 0.000
J02 Acute pharyngitis
0.677 0.323 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.677 0.323 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.677 0.323 0.000
S72.1 Pertrochanteric fracture
0.677 0.323 0.000
E40-E46 Malnutrition
0.675 0.325 0.000
M81.8 Other osteoporosis
0.675 0.325 0.000
M81.6 Localised osteoporosis [Lequesne]
0.675 0.325 0.000
M81.5 Idiopathic osteoporosis
0.675 0.325 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.675 0.325 0.000
M81.2 Osteoporosis of disuse
0.675 0.325 0.000
M81.1 Postoophorectomy osteoporosis
0.675 0.325 0.000
M81.0 Postmenopausal osteoporosis
0.675 0.325 0.000
M31.3 Wegener's granulomatosis
0.674 0.325 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.674 0.326 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.674 0.326 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.674 0.326 0.000
O34.6 Maternal care for abnormality of vagina
0.674 0.326 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.674 0.326 0.000
O34.3 Maternal care for cervical incompetence
0.674 0.326 0.000
O34.0 Maternal care for congenital malformation of uterus
0.674 0.326 0.000
J18.8 Other pneumonia, organism unspecified
0.673 0.327 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.672 0.328 0.000
I27.9 Pulmonary heart disease, unspecified
0.672 0.328 0.000
J30 Vasomotor and allergic rhinitis
0.671 0.329 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.670 0.330 0.000
J18.0 Bronchopneumonia, unspecified
0.669 0.331 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.669 0.331 0.000
J96 Respiratory failure, not elsewhere classified
0.667 0.333 0.000
M51.8 Other specified intervertebral disk disorders
0.667 0.333 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.664 0.336 0.000
O32.2 Maternal care for transverse and oblique lie
0.663 0.336 0.000
M24.5 Contracture of joint
0.663 0.337 0.000
O21 Excessive vomiting in pregnancy
0.663 0.337 0.000
Q50-Q56 Congenital malformations of genital organs
0.663 0.337 0.000
K77 Liver disorders in diseases classified elsewhere
0.663 0.337 0.000
K71 Toxic liver disease
0.663 0.337 0.000
H70 Mastoiditis and related conditions
0.662 0.338 0.000
M25.2 Flail joint
0.661 0.339 0.000
M25.1 Fistula of joint
0.661 0.339 0.000
S00-S09 Injuries to the head
0.661 0.339 0.000
H74.1 Adhesive middle ear disease
0.660 0.339 0.000
M25.84 Other specified joint disorders (Hand)
0.660 0.340 0.000
K65-K67 Diseases of peritoneum
0.660 0.340 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.660 0.340 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.659 0.341 0.000
I20-I25 Ischaemic heart diseases
0.659 0.341 0.000
I42 Cardiomyopathy
0.658 0.342 0.000
J20-J22 Other acute lower respiratory infections
0.658 0.342 0.000
K38 Other diseases of appendix
0.657 0.342 0.000
S81 Open wound of lower leg
0.658 0.342 0.000
J43.2 Centrilobular emphysema
0.657 0.343 0.000
J70 Respiratory conditions due to other external agents
0.657 0.343 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.657 0.343 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.657 0.343 0.000
J66 Airway disease due to specific organic dust
0.657 0.343 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.657 0.343 0.000
J62 Pneumoconiosis due to dust containing silica
0.657 0.343 0.000
J65 Pneumoconiosis associated with tuberculosis
0.657 0.343 0.000
J64 Unspecified pneumoconiosis
0.657 0.343 0.000
J60 Coalworker's pneumoconiosis
0.657 0.343 0.000
M25.53 Pain in joint (Forearm)
0.657 0.343 0.000
J03.8 Acute tonsillitis due to other specified organisms
0.656 0.343 0.000
J03.0 Streptococcal tonsillitis
0.656 0.343 0.000
M35 Other systemic involvement of connective tissue
0.656 0.344 0.000
H74.4 Polyp of middle ear
0.655 0.345 0.000
Chapter VII Diseases of the eye and adnexa
0.655 0.345 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.655 0.345 0.000
O15 Eclampsia
0.654 0.346 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.654 0.346 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.654 0.346 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.654 0.346 0.000
X60-X84 Intentional self-harm
0.654 0.346 0.000
O80-O84 Delivery
0.654 0.346 0.000
G57.8 Other mononeuropathies of lower limb
0.654 0.346 0.000
O73 Retained placenta and membranes, without haemorrhage
0.653 0.347 0.000
G20-G26 Extrapyramidal and movement disorders
0.653 0.347 0.000
G57.0 Lesion of sciatic nerve
0.651 0.349 0.000
O04 Medical abortion
0.651 0.349 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.651 0.349 0.000
J14 Pneumonia due to Haemophilus influenzae
0.650 0.350 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.649 0.350 0.000
Q85 Phakomatoses, not elsewhere classified
0.648 0.352 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.648 0.352 0.000
E86 Volume depletion
0.648 0.352 0.000
X59 Exposure to unspecified factor
0.647 0.353 0.000
J95.0 Tracheostomy malfunction
0.647 0.353 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.646 0.354 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.645 0.355 0.000
O07 Failed attempted abortion
0.645 0.355 0.000
O06 Unspecified abortion
0.645 0.355 0.000
O05 Other abortion
0.645 0.355 0.000
O01 Hydatidiform mole
0.645 0.355 0.000
I05-I09 Chronic rheumatic heart diseases
0.645 0.355 0.000
O00.1 Tubal pregnancy
0.645 0.355 0.000
J17 Pneumonia in diseases classified elsewhere
0.644 0.356 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.644 0.356 0.000
J12 Viral pneumonia, not elsewhere classified
0.644 0.356 0.000
J09 Influenza due to certain identified influenza virus
0.644 0.356 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.644 0.356 0.000
J10 Influenza due to identified influenza virus
0.643 0.357 0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified
0.642 0.358 0.000
E04.1 Non-toxic single thyroid nodule
0.642 0.358 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.642 0.358 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.642 0.358 0.000
Q35-Q37 Cleft lip and cleft palate
0.642 0.358 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.642 0.358 0.000
J35 Chronic diseases of tonsils and adenoids
0.641 0.359 0.000
O75.0 Maternal distress during labour and delivery
0.641 0.359 0.000
T95 Sequelae of burns, corrosions and frostbite
0.641 0.359 0.000
T91 Sequelae of injuries of neck and trunk
0.641 0.359 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.641 0.359 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.641 0.359 0.000
O72.1 Other immediate postpartum haemorrhage
0.641 0.359 0.000
M45-M49 Spondylopathies
0.640 0.360 0.000
S50-S59 Injuries to the elbow and forearm
0.640 0.360 0.000
T98 Sequelae of other and unspecified effects of external causes
0.639 0.360 0.000
M70.6 Trochanteric bursitis
0.639 0.361 0.000
B65-B83 Helminthiases
0.639 0.361 0.000
J31.0 Chronic rhinitis
0.639 0.361 0.000
B34 Viral infection of unspecified site
0.639 0.361 0.000
H80-H83 Diseases of inner ear
0.638 0.362 0.000
O75.8 Other specified complications of labour and delivery
0.637 0.363 0.000
K74.0 Hepatic fibrosis
0.636 0.364 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.635 0.365 0.000
Chapter XXII Codes for special purposes
0.634 0.365 0.000
S72.0 Fracture of neck of femur
0.634 0.366 0.000
M20.3 Other deformity of hallux (acquired)
0.634 0.366 0.000
I45 Other conduction disorders
0.633 0.367 0.000
O02 Other abnormal products of conception
0.633 0.367 0.000
S70.9 Superficial injury of hip and thigh, unspecified
0.633 0.367 0.000
M24.9 Joint derangement, unspecified
0.633 0.367 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.633 0.367 0.000
M24.7 Protrusio acetabuli
0.633 0.367 0.000
M24.6 Ankylosis of joint
0.633 0.367 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.633 0.367 0.000
M24.2 Disorder of ligament
0.633 0.367 0.000
K75.8 Other specified inflammatory liver diseases
0.633 0.367 0.000
G41 Status epilepticus
0.632 0.368 0.000
V20-V29 Motorcycle rider injured in transport accident
0.632 0.368 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.631 0.369 0.000
K36 Other appendicitis
0.631 0.369 0.000
M31.6 Other giant cell arteritis
0.631 0.369 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.630 0.370 0.000
Y00 Assault by blunt object
0.630 0.370 0.000
S78 Traumatic amputation of hip and thigh
0.628 0.372 0.000
S77 Crushing injury of hip and thigh
0.628 0.372 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.628 0.372 0.000
S75 Injury of blood vessels at hip and thigh level
0.628 0.372 0.000
S74 Injury of nerves at hip and thigh level
0.628 0.372 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.628 0.372 0.000
S71 Open wound of hip and thigh
0.628 0.372 0.000
W18 Other fall on same level
0.628 0.372 0.000
G40 Epilepsy
0.628 0.372 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.627 0.373 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.627 0.373 0.000
O30.0 Twin pregnancy
0.627 0.373 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.626 0.374 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.626 0.374 0.000
E00 Congenital iodine-deficiency syndrome
0.626 0.374 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.626 0.374 0.000
W13 Fall from, out of or through building or structure
0.625 0.375 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.624 0.376 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.624 0.376 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.624 0.376 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.624 0.376 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.624 0.376 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.624 0.376 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.624 0.376 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.624 0.376 0.000
K50.1 Crohn's disease of large intestine
0.624 0.376 0.000
I00-I02 Acute rheumatic fever
0.624 0.376 0.000
T56 Toxic effect of metals
0.623 0.377 0.000
B99-B99 Other infectious diseases
0.623 0.377 0.000
I42.9 Cardiomyopathy, unspecified
0.623 0.377 0.000
W20-W49 Exposure to inanimate mechanical forces
0.622 0.378 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.622 0.378 0.000
K31.4 Gastric diverticulum
0.622 0.378 0.000
M71.3 Other bursal cyst
0.621 0.379 0.000
M25.58 Pain in joint (Other)
0.621 0.379 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.621 0.379 0.000
J47 Bronchiectasis
0.621 0.379 0.000
Q82 Other congenital malformations of skin
0.620 0.380 0.000
J43.9 Emphysema, unspecified
0.620 0.380 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.619 0.380 0.000
E55 Vitamin D deficiency
0.619 0.380 0.000
G82 Paraplegia and tetraplegia
0.619 0.380 0.000
E61 Deficiency of other nutrient elements
0.619 0.381 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.619 0.381 0.000
S40-S49 Injuries to the shoulder and upper arm
0.618 0.382 0.000
O48 Prolonged pregnancy
0.618 0.382 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.617 0.383 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.617 0.383 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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