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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs8102280
log Bayes Factor = 30.7378
Chromosome 19   position 19,455,750  (GRCh37) Explore rs8102280 on Ensembl!
Variant rs8102280 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.999 0.001 0.000
K55-K64 Other diseases of intestines
0.998 0.002 0.000
I20 Angina pectoris
0.997 0.003 0.000
Chapter II Neoplasms
0.996 0.004 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.995 0.005 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.995 0.005 0.000
E78.0 Pure hypercholesterolaemia
0.994 0.006 0.000
Chapter V Mental and behavioural disorders
0.993 0.007 0.000
K29 Gastritis and duodenitis
0.992 0.008 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.992 0.008 0.000
K21 Gastro-oesophageal reflux disease
0.984 0.016 0.000
I20.0 Unstable angina
0.983 0.017 0.000
K90-K93 Other diseases of the digestive system
0.982 0.018 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.981 0.019 0.000
I20.9 Angina pectoris, unspecified
0.981 0.019 0.000
Chapter VII Diseases of the eye and adnexa
0.977 0.023 0.000
K90 Intestinal malabsorption
0.975 0.025 0.000
E10-E14 Diabetes mellitus
0.973 0.027 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.972 0.028 0.000
Chapter VI Diseases of the nervous system
0.971 0.029 0.000
K57 Diverticular disease of intestine
0.971 0.029 0.000
K90.0 Coeliac disease
0.970 0.030 0.000
M20-M25 Other joint disorders
0.970 0.030 0.000
R12 Heartburn
0.970 0.030 0.000
Chapter VIII Diseases of the ear and mastoid process
0.966 0.034 0.000
R50-R69 General symptoms and signs
0.966 0.034 0.000
D10-D36 Benign neoplasms
0.963 0.037 0.000
R13 Dysphagia
0.961 0.039 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.956 0.044 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.955 0.045 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.954 0.046 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.951 0.049 0.000
M25 Other joint disorders, not elsewhere classified
0.949 0.051 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.949 0.051 0.000
I60-I69 Cerebrovascular diseases
0.944 0.056 0.000
K29.7 Gastritis, unspecified
0.940 0.060 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.938 0.062 0.000
R20 Disturbances of skin sensation
0.936 0.064 0.000
E78.5 Hyperlipidaemia, unspecified
0.934 0.066 0.000
I25 Chronic ischaemic heart disease
0.931 0.069 0.000
E11 Non-insulin-dependent diabetes mellitus
0.931 0.069 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.928 0.072 0.000
G40-G47 Episodic and paroxysmal disorders
0.927 0.073 0.000
K62 Other diseases of anus and rectum
0.924 0.076 0.000
S00-S09 Injuries to the head
0.922 0.078 0.000
H30-H36 Disorders of choroid and retina
0.921 0.079 0.000
Z51 Other medical care
0.921 0.079 0.000
Z02 Examination and encounter for administrative purposes
0.919 0.081 0.000
R56 Convulsions, not elsewhere classified
0.918 0.082 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.917 0.083 0.000
S60-S69 Injuries to the wrist and hand
0.917 0.083 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.910 0.090 0.000
I10-I15 Hypertensive diseases
0.909 0.091 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.907 0.093 0.000
R30-R39 Symptoms and signs involving the urinary system
0.906 0.094 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.905 0.095 0.000
C64-C68 Malignant neoplasms of urinary tract
0.905 0.095 0.000
K29.6 Other gastritis
0.902 0.098 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.902 0.098 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.902 0.098 0.000
K62.5 Haemorrhage of anus and rectum
0.902 0.098 0.000
K31 Other diseases of stomach and duodenum
0.898 0.102 0.000
E11.9 Without complications
0.898 0.102 0.000
Chapter I Certain infectious and parasitic diseases
0.898 0.102 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.891 0.109 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.891 0.109 0.000
R56.8 Other and unspecified convulsions
0.884 0.116 0.000
R53 Malaise and fatigue
0.881 0.119 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.881 0.119 0.000
H25-H28 Disorders of lens
0.877 0.123 0.000
R31 Unspecified haematuria
0.875 0.125 0.000
M25.5 Pain in joint
0.873 0.127 0.000
I69 Sequelae of cerebrovascular disease
0.872 0.128 0.000
Chapter X Diseases of the respiratory system
0.871 0.129 0.000
H90-H95 Other disorders of ear
0.871 0.129 0.000
E10 Insulin-dependent diabetes mellitus
0.871 0.129 0.000
R20.2 Paraesthesia of skin
0.869 0.131 0.000
R59 Enlarged lymph nodes
0.868 0.132 0.000
H35 Other retinal disorders
0.867 0.133 0.000
Z02.8 Other examinations for administrative purposes
0.865 0.135 0.000
E86 Volume depletion
0.864 0.136 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.863 0.137 0.000
K29.5 Chronic gastritis, unspecified
0.861 0.139 0.000
G90-G99 Other disorders of the nervous system
0.859 0.141 0.000
R21 Rash and other nonspecific skin eruption
0.856 0.144 0.000
Z13 Special screening examination for other diseases and disorders
0.854 0.146 0.000
I25.1 Atherosclerotic heart disease
0.853 0.147 0.000
M25.4 Effusion of joint
0.850 0.150 0.000
G40 Epilepsy
0.849 0.150 0.000
H65-H75 Diseases of middle ear and mastoid
0.848 0.152 0.000
Z51.2 Other chemotherapy
0.847 0.153 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.846 0.154 0.000
K55 Vascular disorders of intestine
0.846 0.154 0.000
M22 Disorders of patella
0.846 0.154 0.000
R63 Symptoms and signs concerning food and fluid intake
0.845 0.155 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.841 0.159 0.000
R47-R49 Symptoms and signs involving speech and voice
0.840 0.160 0.000
M65-M68 Disorders of synovium and tendon
0.839 0.161 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.837 0.163 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.837 0.163 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.836 0.164 0.000
M80-M85 Disorders of bone density and structure
0.836 0.164 0.000
H25 Senile cataract
0.835 0.165 0.000
K70-K77 Diseases of liver
0.834 0.166 0.000
K61 Abscess of anal and rectal regions
0.834 0.166 0.000
K20 Oesophagitis
0.833 0.167 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.833 0.167 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.833 0.167 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.832 0.168 0.000
M23 Internal derangement of knee
0.831 0.169 0.000
K25 Gastric ulcer
0.830 0.170 0.000
T66-T78 Other and unspecified effects of external causes
0.830 0.170 0.000
F10.0 Acute intoxication
0.828 0.172 0.000
D23 Other benign neoplasms of skin
0.828 0.172 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.828 0.172 0.000
I67 Other cerebrovascular diseases
0.827 0.173 0.000
E88 Other metabolic disorders
0.826 0.174 0.000
H43-H45 Disorders of vitreous body and globe
0.826 0.174 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.823 0.177 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.822 0.178 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.819 0.181 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.818 0.182 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.817 0.183 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.813 0.187 0.000
S00 Superficial injury of head
0.812 0.188 0.000
D27 Benign neoplasm of ovary
0.811 0.189 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.810 0.190 0.000
E87.7 Fluid overload
0.809 0.191 0.000
C79 Secondary malignant neoplasm of other sites
0.808 0.192 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.807 0.193 0.000
H25.1 Senile nuclear cataract
0.806 0.194 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.801 0.199 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.801 0.199 0.000
D18 Haemangioma and lymphangioma, any site
0.800 0.200 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.800 0.200 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.799 0.201 0.000
H80-H83 Diseases of inner ear
0.798 0.202 0.000
Z48 Other surgical follow-up care
0.798 0.202 0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen
0.798 0.202 0.000
K31.7 Polyp of stomach and duodenum
0.798 0.202 0.000
Z51.8 Other specified medical care
0.798 0.202 0.000
S40-S49 Injuries to the shoulder and upper arm
0.798 0.202 0.000
R59.0 Localised enlarged lymph nodes
0.798 0.202 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.797 0.203 0.000
F41 Other anxiety disorders
0.795 0.205 0.000
M40-M43 Deforming dorsopathies
0.795 0.205 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.794 0.205 0.000
F30-F39 Mood [affective] disorders
0.792 0.208 0.000
E00-E07 Disorders of thyroid gland
0.791 0.209 0.000
B35-B49 Mycoses
0.790 0.210 0.000
I69.3 Sequelae of cerebral infarction
0.790 0.210 0.000
C67 Malignant neoplasm of bladder
0.789 0.211 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.788 0.211 0.000
K63 Other diseases of intestine
0.789 0.211 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.787 0.213 0.000
S20-S29 Injuries to the thorax
0.787 0.213 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.786 0.214 0.000
E20-E35 Disorders of other endocrine glands
0.786 0.214 0.000
L20-L30 Dermatitis and eczema
0.785 0.215 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.785 0.215 0.000
H35.3 Degeneration of macula and posterior pole
0.785 0.215 0.000
I10 Essential (primary) hypertension
0.785 0.215 0.000
S01 Open wound of head
0.784 0.216 0.000
M45-M49 Spondylopathies
0.783 0.217 0.000
R52 Pain, not elsewhere classified
0.782 0.218 0.000
K29.3 Chronic superficial gastritis
0.780 0.220 0.000
H53-H54 Visual disturbances and blindness
0.780 0.220 0.000
E40-E46 Malnutrition
0.779 0.221 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.778 0.222 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.776 0.224 0.000
B95-B98 Bacterial, viral and other infectious agents
0.775 0.225 0.000
K40-K46 Hernia
0.775 0.225 0.000
I12 Hypertensive renal disease
0.773 0.227 0.000
G44 Other headache syndromes
0.773 0.227 0.000
Z13.9 Special screening examination, unspecified
0.773 0.227 0.000
S62 Fracture at wrist and hand level
0.767 0.233 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.766 0.234 0.000
F10.2 Dependence syndrome
0.766 0.234 0.000
G43 Migraine
0.765 0.235 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.765 0.235 0.000
M05-M14 Inflammatory polyarthropathies
0.765 0.235 0.000
E50-E64 Other nutritional deficiencies
0.764 0.236 0.000
M25.7 Osteophyte
0.763 0.237 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.762 0.238 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.761 0.238 0.000
D23.7 Skin of lower limb, including hip
0.761 0.239 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.760 0.239 0.000
H66 Suppurative and unspecified otitis media
0.760 0.240 0.000
H93 Other disorders of ear, not elsewhere classified
0.760 0.240 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.759 0.241 0.000
M70-M79 Other soft tissue disorders
0.759 0.241 0.000
M25.46 Effusion of joint (Lower leg)
0.758 0.242 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.758 0.242 0.000
E10.3 With ophthalmic complications
0.758 0.242 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.758 0.242 0.000
H36 Retinal disorders in diseases classified elsewhere
0.756 0.244 0.000
E83 Disorders of mineral metabolism
0.755 0.245 0.000
L60-L75 Disorders of skin appendages
0.755 0.245 0.000
C77.2 Intra-abdominal lymph nodes
0.754 0.246 0.000
R63.0 Anorexia
0.752 0.248 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.751 0.249 0.000
Chapter XIV Diseases of the genitourinary system
0.751 0.249 0.000
L40-L45 Papulosquamous disorders
0.750 0.250 0.000
R14 Flatulence and related conditions
0.750 0.250 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.750 0.250 0.000
J40-J47 Chronic lower respiratory diseases
0.749 0.251 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.749 0.251 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.748 0.252 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.748 0.252 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.747 0.253 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.747 0.253 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.747 0.253 0.000
Chapter XXII Codes for special purposes
0.746 0.254 0.000
I67.8 Other specified cerebrovascular diseases
0.746 0.254 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.745 0.255 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.744 0.256 0.000
I05-I09 Chronic rheumatic heart diseases
0.743 0.257 0.000
S50-S59 Injuries to the elbow and forearm
0.743 0.257 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.743 0.257 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.742 0.258 0.000
K27 Peptic ulcer, site unspecified
0.742 0.258 0.000
H10-H13 Disorders of conjunctiva
0.741 0.259 0.000
F10.4 Withdrawal state with delirium
0.741 0.259 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.740 0.260 0.000
R50 Fever of unknown origin
0.740 0.260 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.740 0.260 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.739 0.261 0.000
K29.1 Other acute gastritis
0.739 0.261 0.000
K60 Fissure and fistula of anal and rectal regions
0.737 0.262 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.736 0.264 0.000
H35.8 Other specified retinal disorders
0.735 0.265 0.000
M23.3 Other meniscus derangements
0.735 0.265 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.735 0.265 0.000
Z34 Supervision of normal pregnancy
0.734 0.266 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.734 0.266 0.000
K12 Stomatitis and related lesions
0.733 0.267 0.000
K26 Duodenal ulcer
0.732 0.267 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.732 0.268 0.000
S69 Other and unspecified injuries of wrist and hand
0.731 0.269 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.731 0.269 0.000
Z36 Antenatal screening
0.730 0.270 0.000
M86-M90 Other osteopathies
0.727 0.272 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.727 0.273 0.000
E87.6 Hypokalaemia
0.727 0.273 0.000
C80 Malignant neoplasm without specification of site
0.727 0.273 0.000
F43 Reaction to severe stress, and adjustment disorders
0.726 0.273 0.000
M25.53 Pain in joint (Forearm)
0.726 0.274 0.000
E87.5 Hyperkalaemia
0.726 0.274 0.000
R11 Nausea and vomiting
0.724 0.276 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.724 0.276 0.000
M25.51 Pain in joint (Shoulder region)
0.723 0.277 0.000
Z50 Care involving use of rehabilitation procedures
0.723 0.277 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.723 0.277 0.000
S90-S99 Injuries to the ankle and foot
0.723 0.277 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.723 0.277 0.000
K57.1 Diverticular disease of small intestine without perforation or abscess
0.722 0.278 0.000
Z30 Contraceptive management
0.722 0.278 0.000
R60 Oedema, not elsewhere classified
0.721 0.278 0.000
Z35 Supervision of high-risk pregnancy
0.721 0.279 0.000
K09 Cysts of oral region, not elsewhere classified
0.721 0.279 0.000
M65 Synovitis and tenosynovitis
0.721 0.279 0.000
K29.0 Acute haemorrhagic gastritis
0.720 0.279 0.000
K05 Gingivitis and periodontal diseases
0.720 0.280 0.000
K44 Diaphragmatic hernia
0.718 0.282 0.000
K02 Dental caries
0.718 0.282 0.000
H43 Disorders of vitreous body
0.717 0.283 0.000
Z95.2 Presence of prosthetic heart valve
0.717 0.283 0.000
R40 Somnolence, stupor and coma
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E85 Amyloidosis
0.717 0.283 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E74 Other disorders of carbohydrate metabolism
0.717 0.283 0.000
E73 Lactose intolerance
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
K28 Gastrojejunal ulcer
0.717 0.283 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.717 0.283 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.716 0.283 0.000
K65-K67 Diseases of peritoneum
0.716 0.284 0.000
K61.0 Anal abscess
0.716 0.284 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.716 0.284 0.000
Z51.5 Palliative care
0.716 0.284 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.716 0.284 0.000
E78.8 Other disorders of lipoprotein metabolism
0.716 0.284 0.000
E78.6 Lipoprotein deficiency
0.716 0.284 0.000
E78.4 Other hyperlipidaemia
0.716 0.284 0.000
E78.3 Hyperchylomicronaemia
0.716 0.284 0.000
E78.2 Mixed hyperlipidaemia
0.716 0.284 0.000
E78.1 Pure hyperglyceridaemia
0.716 0.284 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.715 0.285 0.000
I20.1 Angina pectoris with documented spasm
0.715 0.285 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.714 0.286 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.714 0.286 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.714 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.714 0.286 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.714 0.286 0.000
Z03.8 Observation for other suspected diseases and conditions
0.714 0.286 0.000
B37 Candidiasis
0.714 0.286 0.000
Z10 Routine general health check-up of defined subpopulation
0.713 0.287 0.000
D25 Leiomyoma of uterus
0.713 0.287 0.000
F99-F99 Unspecified mental disorder
0.712 0.288 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.288 0.000
F80-F89 Disorders of psychological development
0.712 0.288 0.000
F70-F79 Mental retardation
0.712 0.288 0.000
F60-F69 Disorders of adult personality and behaviour
0.712 0.288 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.712 0.288 0.000
Z33 Pregnant state, incidental
0.711 0.289 0.000
K29.9 Gastroduodenitis, unspecified
0.711 0.289 0.000
K29.4 Chronic atrophic gastritis
0.711 0.289 0.000
K29.2 Alcoholic gastritis
0.711 0.289 0.000
M91-M94 Chondropathies
0.711 0.289 0.000
M60-M63 Disorders of muscles
0.711 0.289 0.000
M00-M03 Infectious arthropathies
0.711 0.289 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.710 0.289 0.000
E10.9 Without complications
0.710 0.290 0.000
J00-J06 Acute upper respiratory infections
0.709 0.290 0.000
K55.2 Angiodysplasia of colon
0.709 0.290 0.000
T78 Adverse effects, not elsewhere classified
0.708 0.292 0.000
Z51.0 Radiotherapy session
0.708 0.292 0.000
R10 Abdominal and pelvic pain
0.707 0.293 0.000
R61 Hyperhidrosis
0.707 0.293 0.000
G30-G32 Other degenerative diseases of the nervous system
0.707 0.293 0.000
S61 Open wound of wrist and hand
0.707 0.293 0.000
M22.4 Chondromalacia patellae
0.707 0.293 0.000
S00.9 Superficial injury of head, part unspecified
0.705 0.294 0.000
C67.9 Bladder, unspecified
0.705 0.295 0.000
H60-H62 Diseases of external ear
0.705 0.295 0.000
Z22 Carrier of infectious disease
0.705 0.295 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.704 0.296 0.000
R23 Other skin changes
0.704 0.296 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.703 0.297 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.703 0.297 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.702 0.298 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.702 0.298 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.702 0.298 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.701 0.299 0.000
Z04 Examination and observation for other reasons
0.701 0.299 0.000
H55-H59 Other disorders of eye and adnexa
0.701 0.299 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.701 0.299 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.701 0.299 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.700 0.300 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.700 0.300 0.000
K90.9 Intestinal malabsorption, unspecified
0.699 0.301 0.000
K90.8 Other intestinal malabsorption
0.699 0.301 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.699 0.301 0.000
K90.3 Pancreatic steatorrhoea
0.699 0.301 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.699 0.301 0.000
K90.1 Tropical sprue
0.699 0.301 0.000
C51-C58 Malignant neoplasms of female genital organs
0.699 0.301 0.000
C77.8 Lymph nodes of multiple regions
0.699 0.301 0.000
K08 Other disorders of teeth and supporting structures
0.699 0.301 0.000
Z45 Adjustment and management of implanted device
0.699 0.301 0.000
E13 Other specified diabetes mellitus
0.697 0.303 0.000
E12 Malnutrition-related diabetes mellitus
0.697 0.303 0.000
J20-J22 Other acute lower respiratory infections
0.697 0.303 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.697 0.303 0.000
Z09.4 Follow-up examination after treatment of fracture
0.697 0.303 0.000
Z09.3 Follow-up examination after psychotherapy
0.697 0.303 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.697 0.303 0.000
D24 Benign neoplasm of breast
0.697 0.303 0.000
G70-G73 Diseases of myoneural junction and muscle
0.696 0.303 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.696 0.303 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.696 0.304 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.696 0.304 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.696 0.304 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.696 0.304 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.696 0.304 0.000
K22 Other diseases of oesophagus
0.696 0.304 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.696 0.304 0.000
M34 Systemic sclerosis
0.696 0.304 0.000
M33 Dermatopolymyositis
0.696 0.304 0.000
M32 Systemic lupus erythematosus
0.696 0.304 0.000
M30 Polyarteritis nodosa and related conditions
0.696 0.304 0.000
M21 Other acquired deformities of limbs
0.696 0.304 0.000
G93 Other disorders of brain
0.695 0.305 0.000
E11.3 With ophthalmic complications
0.695 0.305 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.694 0.306 0.000
M31 Other necrotising vasculopathies
0.693 0.307 0.000
I62 Other nontraumatic intracranial haemorrhage
0.693 0.307 0.000
R68 Other general symptoms and signs
0.693 0.307 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.693 0.307 0.000
R62 Lack of expected normal physiological development
0.693 0.307 0.000
R57 Shock, not elsewhere classified
0.693 0.307 0.000
R64 Cachexia
0.693 0.307 0.000
R58 Haemorrhage, not elsewhere classified
0.693 0.307 0.000
R54 Senility
0.693 0.307 0.000
M81 Osteoporosis without pathological fracture
0.693 0.307 0.000
M25.57 Pain in joint (Ankle and foot)
0.693 0.307 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.692 0.308 0.000
K04 Diseases of pulp and periapical tissues
0.692 0.308 0.000
M22.2 Patellofemoral disorders
0.692 0.308 0.000
K01 Embedded and impacted teeth
0.691 0.309 0.000
R17 Unspecified jaundice
0.691 0.309 0.000
D32 Benign neoplasm of meninges
0.691 0.309 0.000
D31 Benign neoplasm of eye and adnexa
0.691 0.309 0.000
D30 Benign neoplasm of urinary organs
0.691 0.309 0.000
D29 Benign neoplasm of male genital organs
0.691 0.309 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.691 0.309 0.000
D26 Other benign neoplasms of uterus
0.691 0.309 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.691 0.309 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.691 0.309 0.000
D19 Benign neoplasm of mesothelial tissue
0.691 0.309 0.000
D16 Benign neoplasm of bone and articular cartilage
0.691 0.309 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.691 0.309 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.691 0.309 0.000
D11 Benign neoplasm of major salivary glands
0.691 0.309 0.000
D10 Benign neoplasm of mouth and pharynx
0.691 0.309 0.000
D34 Benign neoplasm of thyroid gland
0.691 0.309 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.690 0.310 0.000
R49 Voice disturbances
0.690 0.310 0.000
S02 Fracture of skull and facial bones
0.689 0.311 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.688 0.312 0.000
F41.1 Generalised anxiety disorder
0.688 0.312 0.000
C78.7 Secondary malignant neoplasm of liver
0.687 0.313 0.000
K62.8 Other specified diseases of anus and rectum
0.687 0.313 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.687 0.313 0.000
H81 Disorders of vestibular function
0.686 0.314 0.000
F45 Somatoform disorders
0.686 0.314 0.000
Z95.1 Presence of aortocoronary bypass graft
0.686 0.314 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.685 0.315 0.000
F10.3 Withdrawal state
0.684 0.316 0.000
D18.0 Haemangioma, any site
0.683 0.317 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.683 0.317 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.682 0.318 0.000
K07 Dentofacial anomalies [including malocclusion]
0.682 0.318 0.000
K31.8 Other specified diseases of stomach and duodenum
0.682 0.318 0.000
Z54 Convalescence
0.682 0.318 0.000
Z52 Donors of organs and tissues
0.682 0.318 0.000
Z49 Care involving dialysis
0.682 0.318 0.000
Z44 Fitting and adjustment of external prosthetic device
0.682 0.318 0.000
I74 Arterial embolism and thrombosis
0.681 0.319 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.681 0.319 0.000
M25.9 Joint disorder, unspecified
0.681 0.319 0.000
M25.8 Other specified joint disorders
0.681 0.319 0.000
M25.3 Other instability of joint
0.681 0.319 0.000
M25.2 Flail joint
0.681 0.319 0.000
M25.1 Fistula of joint
0.681 0.319 0.000
M25.0 Haemarthrosis
0.681 0.319 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.681 0.319 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.681 0.319 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.681 0.319 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.681 0.319 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.681 0.319 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.681 0.319 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.681 0.319 0.000
F11 Mental and behavioural disorders due to use of opioids
0.681 0.319 0.000
K35-K38 Diseases of appendix
0.681 0.319 0.000
H25.8 Other senile cataract
0.681 0.319 0.000
H93.1 Tinnitus
0.680 0.319 0.000
K70 Alcoholic liver disease
0.680 0.320 0.000
H91 Other hearing loss
0.678 0.322 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.678 0.322 0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.677 0.323 0.000
D36 Benign neoplasm of other and unspecified sites
0.677 0.323 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.677 0.323 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.677 0.323 0.000
I95 Hypotension
0.676 0.324 0.000
F17.2 Dependence syndrome
0.676 0.324 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.676 0.324 0.000
K62.4 Stenosis of anus and rectum
0.674 0.325 0.000
G95 Other diseases of spinal cord
0.674 0.326 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.674 0.326 0.000
H90 Conductive and sensorineural hearing loss
0.674 0.326 0.000
B25-B34 Other viral diseases
0.674 0.326 0.000
I63 Cerebral infarction
0.674 0.326 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.674 0.326 0.000
K57.3 Diverticular disease of large intestine without perforation or abscess
0.672 0.328 0.000
C77.1 Intrathoracic lymph nodes
0.672 0.328 0.000
L29 Pruritus
0.672 0.328 0.000
R20.3 Hyperaesthesia
0.671 0.329 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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