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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs8127967
log Bayes Factor = 12.6191
Chromosome 21   position 21,763,036  (GRCh37) Explore rs8127967 on Ensembl!
Variant rs8127967 is part of Cluster X0154

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.998 0.002 0.000
M05-M14 Inflammatory polyarthropathies
0.996 0.004 0.000
Chapter VI Diseases of the nervous system
0.996 0.004 0.000
O60-O75 Complications of labour and delivery
0.993 0.007 0.000
M06 Other rheumatoid arthritis
0.991 0.009 0.000
M06.9 Rheumatoid arthritis, unspecified
0.988 0.012 0.000
O70 Perineal laceration during delivery
0.984 0.016 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.980 0.020 0.000
G40-G47 Episodic and paroxysmal disorders
0.979 0.021 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.975 0.025 0.000
M80-M85 Disorders of bone density and structure
0.975 0.025 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.973 0.027 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.967 0.033 0.000
Chapter XX External causes of morbidity and mortality
0.966 0.034 0.000
E00-E07 Disorders of thyroid gland
0.957 0.043 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.957 0.043 0.000
O80-O84 Delivery
0.956 0.044 0.000
Chapter XXI Factors influencing health status and contact with health services
0.955 0.045 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.955 0.045 0.000
Chapter X Diseases of the respiratory system
0.954 0.046 0.000
G30-G32 Other degenerative diseases of the nervous system
0.952 0.048 0.000
E04 Other non-toxic goitre
0.952 0.048 0.000
G40 Epilepsy
0.950 0.050 0.000
E20-E35 Disorders of other endocrine glands
0.948 0.052 0.000
E04.2 Non-toxic multinodular goitre
0.945 0.055 0.000
O70.1 Second degree perineal laceration during delivery
0.940 0.060 0.000
Chapter I Certain infectious and parasitic diseases
0.939 0.061 0.000
J00-J06 Acute upper respiratory infections
0.939 0.061 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.937 0.063 0.000
O36 Maternal care for other known or suspected foetal problems
0.931 0.069 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.928 0.072 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.927 0.073 0.000
M13 Other arthritis
0.927 0.073 0.000
G43 Migraine
0.923 0.077 0.000
G30 Alzheimer's disease
0.920 0.080 0.000
Z37 Outcome of delivery
0.919 0.081 0.000
Z36 Antenatal screening
0.914 0.086 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.910 0.090 0.000
J00 Acute nasopharyngitis [common cold]
0.906 0.094 0.000
M81 Osteoporosis without pathological fracture
0.900 0.100 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.900 0.100 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.898 0.102 0.000
M20-M25 Other joint disorders
0.897 0.103 0.000
Chapter VIII Diseases of the ear and mastoid process
0.894 0.106 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.893 0.107 0.000
Z37.0 Single live birth
0.886 0.114 0.000
E27 Other disorders of adrenal gland
0.886 0.114 0.000
G30.9 Alzheimer's disease, unspecified
0.884 0.116 0.000
O36.8 Maternal care for other specified foetal problems
0.880 0.120 0.000
Z35 Supervision of high-risk pregnancy
0.879 0.121 0.000
O46.9 Antepartum haemorrhage, unspecified
0.878 0.122 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.877 0.123 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.876 0.124 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.875 0.125 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.875 0.125 0.000
O48 Prolonged pregnancy
0.875 0.125 0.000
O70.2 Third degree perineal laceration during delivery
0.873 0.127 0.000
Z34 Supervision of normal pregnancy
0.873 0.127 0.000
Chapter VII Diseases of the eye and adnexa
0.872 0.128 0.000
O80 Single spontaneous delivery
0.871 0.129 0.000
O70.0 First degree perineal laceration during delivery
0.870 0.130 0.000
H30-H36 Disorders of choroid and retina
0.861 0.139 0.000
W00-W19 Falls
0.857 0.143 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.857 0.143 0.000
O82 Single delivery by Caesarean section
0.856 0.144 0.000
G43.9 Migraine, unspecified
0.854 0.146 0.000
G40.9 Epilepsy, unspecified
0.854 0.146 0.000
M13.9 Arthritis, unspecified
0.853 0.147 0.000
H35 Other retinal disorders
0.849 0.151 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.847 0.153 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.847 0.153 0.000
E04.1 Non-toxic single thyroid nodule
0.845 0.155 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.845 0.155 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.843 0.157 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.838 0.162 0.000
M40-M43 Deforming dorsopathies
0.838 0.162 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.837 0.163 0.000
Chapter V Mental and behavioural disorders
0.836 0.164 0.000
M80 Osteoporosis with pathological fracture
0.831 0.169 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.829 0.171 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.827 0.173 0.000
G62 Other polyneuropathies
0.827 0.173 0.000
M84 Disorders of continuity of bone
0.827 0.173 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.824 0.176 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.823 0.177 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.822 0.178 0.000
Chapter XXII Codes for special purposes
0.820 0.180 0.000
Z35.0 Supervision of pregnancy with history of infertility
0.819 0.181 0.000
M23 Internal derangement of knee
0.818 0.182 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.818 0.182 0.000
O42 Premature rupture of membranes
0.817 0.183 0.000
B35-B49 Mycoses
0.816 0.184 0.000
M45-M49 Spondylopathies
0.816 0.184 0.000
T79-T79 Certain early complications of trauma
0.816 0.184 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.815 0.185 0.000
B15-B19 Viral hepatitis
0.814 0.186 0.000
T42.4 Benzodiazepines
0.813 0.187 0.000
A00-A09 Intestinal infectious diseases
0.813 0.187 0.000
O72 Postpartum haemorrhage
0.813 0.187 0.000
X60-X84 Intentional self-harm
0.808 0.192 0.000
O36.9 Maternal care for foetal problem, unspecified
0.804 0.196 0.000
Chapter II Neoplasms
0.803 0.197 0.000
J90-J94 Other diseases of pleura
0.802 0.198 0.000
F30-F39 Mood [affective] disorders
0.801 0.199 0.000
J06.9 Acute upper respiratory infection, unspecified
0.798 0.202 0.000
O80.9 Single spontaneous delivery, unspecified
0.798 0.202 0.000
E27.1 Primary adrenocortical insufficiency
0.798 0.202 0.000
M21 Other acquired deformities of limbs
0.797 0.203 0.000
M86-M90 Other osteopathies
0.795 0.205 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.795 0.205 0.000
S70-S79 Injuries to the hip and thigh
0.793 0.207 0.000
H65-H75 Diseases of middle ear and mastoid
0.793 0.207 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.793 0.207 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.792 0.208 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.792 0.208 0.000
M91-M94 Chondropathies
0.792 0.208 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.791 0.209 0.000
M81.9 Osteoporosis, unspecified
0.791 0.209 0.000
H35.8 Other specified retinal disorders
0.788 0.212 0.000
W20-W49 Exposure to inanimate mechanical forces
0.787 0.213 0.000
C34 Malignant neoplasm of bronchus and lung
0.787 0.213 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.783 0.217 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.782 0.218 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.781 0.219 0.000
Z36.9 Antenatal screening, unspecified
0.781 0.219 0.000
T92 Sequelae of injuries of upper limb
0.780 0.220 0.000
C34.9 Bronchus or lung, unspecified
0.779 0.221 0.000
M60-M63 Disorders of muscles
0.777 0.223 0.000
G81 Hemiplegia
0.775 0.225 0.000
J09-J18 Influenza and pneumonia
0.775 0.225 0.000
O40 Polyhydramnios
0.774 0.226 0.000
M06.4 Inflammatory polyarthropathy
0.772 0.228 0.000
G43.1 Migraine with aura [classical migraine]
0.771 0.229 0.000
E24 Cushing's syndrome
0.771 0.229 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.769 0.230 0.000
O82.0 Delivery by elective Caesarean section
0.768 0.232 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.768 0.232 0.000
H60-H62 Diseases of external ear
0.767 0.233 0.000
O30 Multiple gestation
0.767 0.233 0.000
G62.8 Other specified polyneuropathies
0.766 0.234 0.000
O43 Placental disorders
0.766 0.234 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.764 0.236 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.764 0.236 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.764 0.236 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.762 0.238 0.000
S10-S19 Injuries to the neck
0.761 0.239 0.000
S40-S49 Injuries to the shoulder and upper arm
0.761 0.239 0.000
J60-J70 Lung diseases due to external agents
0.759 0.241 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.759 0.241 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.759 0.241 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.758 0.242 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.758 0.242 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.757 0.243 0.000
Z57 Occupational exposure to risk-factors
0.757 0.243 0.000
G30.0 Alzheimer's disease with early onset
0.756 0.244 0.000
A08 Viral and other specified intestinal infections
0.756 0.244 0.000
G41 Status epilepticus
0.753 0.247 0.000
O66 Other obstructed labour
0.752 0.248 0.000
O70.9 Perineal laceration during delivery, unspecified
0.752 0.248 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.752 0.248 0.000
O61 Failed induction of labour
0.750 0.250 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.750 0.250 0.000
M13.0 Polyarthritis, unspecified
0.750 0.250 0.000
T90 Sequelae of injuries of head
0.747 0.253 0.000
E34 Other endocrine disorders
0.746 0.253 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.746 0.254 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.746 0.254 0.000
H35.9 Retinal disorder, unspecified
0.746 0.254 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.745 0.255 0.000
Z34.8 Supervision of other normal pregnancy
0.744 0.255 0.000
Z60 Problems related to social environment
0.742 0.258 0.000
H53-H54 Visual disturbances and blindness
0.742 0.258 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.742 0.258 0.000
O72.0 Third-stage haemorrhage
0.740 0.260 0.000
Z37.1 Single stillbirth
0.740 0.260 0.000
O71 Other obstetric trauma
0.740 0.260 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.738 0.262 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.738 0.262 0.000
J01 Acute sinusitis
0.737 0.263 0.000
M22 Disorders of patella
0.735 0.265 0.000
M85 Other disorders of bone density and structure
0.734 0.266 0.000
V80-V89 Other land transport accidents
0.733 0.267 0.000
E20 Hypoparathyroidism
0.732 0.268 0.000
M23.8 Other internal derangements of knee
0.732 0.268 0.000
O44 Placenta praevia
0.731 0.269 0.000
M00-M03 Infectious arthropathies
0.731 0.269 0.000
E06 Thyroiditis
0.730 0.270 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.728 0.272 0.000
T43.2 Other and unspecified antidepressants
0.727 0.273 0.000
O63 Long labour
0.726 0.274 0.000
M81.4 Drug-induced osteoporosis
0.725 0.275 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.724 0.276 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.722 0.278 0.000
H55-H59 Other disorders of eye and adnexa
0.722 0.278 0.000
M81.2 Osteoporosis of disuse
0.721 0.279 0.000
H35.3 Degeneration of macula and posterior pole
0.721 0.279 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.720 0.280 0.000
W19 Unspecified fall
0.719 0.281 0.000
O20 Haemorrhage in early pregnancy
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G61 Inflammatory polyneuropathy
0.716 0.284 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.716 0.284 0.000
O45 Premature separation of placenta [abruptio placentae]
0.715 0.284 0.000
O33 Maternal care for known or suspected disproportion
0.715 0.284 0.000
O31 Complications specific to multiple gestation
0.715 0.284 0.000
M47 Spondylosis
0.715 0.285 0.000
F31 Bipolar affective disorder
0.715 0.285 0.000
M14 Arthropathies in other diseases classified elsewhere
0.714 0.286 0.000
M12 Other specific arthropathies
0.714 0.286 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.714 0.286 0.000
M08 Juvenile arthritis
0.714 0.286 0.000
A08.4 Viral intestinal infection, unspecified
0.714 0.286 0.000
O85-O92 Complications predominantly related to the puerperium
0.714 0.286 0.000
Z63 Other problems related to primary support group, including family circumstances
0.713 0.287 0.000
E07 Other disorders of thyroid
0.712 0.288 0.000
O74 Complications of anaesthesia during labour and delivery
0.712 0.288 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.712 0.288 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.712 0.288 0.000
O60 Preterm delivery
0.712 0.288 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.711 0.288 0.000
M06.8 Other specified rheumatoid arthritis
0.711 0.289 0.000
M06.3 Rheumatoid nodule
0.711 0.289 0.000
M06.2 Rheumatoid bursitis
0.711 0.289 0.000
M06.1 Adult-onset Still's disease
0.711 0.289 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.711 0.289 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.711 0.289 0.000
O21 Excessive vomiting in pregnancy
0.710 0.290 0.000
G44 Other headache syndromes
0.709 0.291 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.709 0.291 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.709 0.291 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.709 0.291 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.709 0.291 0.000
C15-C26 Malignant neoplasms of digestive organs
0.708 0.292 0.000
M70-M79 Other soft tissue disorders
0.706 0.294 0.000
J91 Pleural effusion in conditions classified elsewhere
0.706 0.294 0.000
O70.3 Fourth degree perineal laceration during delivery
0.706 0.294 0.000
M65-M68 Disorders of synovium and tendon
0.705 0.294 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.705 0.295 0.000
H65 Nonsuppurative otitis media
0.705 0.295 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.704 0.296 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.704 0.296 0.000
B18 Chronic viral hepatitis
0.704 0.296 0.000
T86 Failure and rejection of transplanted organs and tissues
0.704 0.296 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.703 0.297 0.000
G81.9 Hemiplegia, unspecified
0.703 0.297 0.000
T87 Complications peculiar to reattachment and amputation
0.702 0.297 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.702 0.297 0.000
W29 Contact with other powered hand tools and household machinery
0.702 0.298 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.702 0.298 0.000
E23 Hypofunction and other disorders of pituitary gland
0.701 0.299 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.699 0.301 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.699 0.301 0.000
M83 Adult osteomalacia
0.699 0.301 0.000
M82 Osteoporosis in diseases classified elsewhere
0.699 0.301 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.698 0.302 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.698 0.302 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.698 0.302 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.698 0.302 0.000
B37 Candidiasis
0.698 0.302 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.697 0.303 0.000
Z58 Problems related to physical environment
0.696 0.304 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.695 0.305 0.000
S90-S99 Injuries to the ankle and foot
0.694 0.306 0.000
Z35.8 Supervision of other high-risk pregnancies
0.694 0.306 0.000
W06 Fall involving bed
0.693 0.307 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.693 0.307 0.000
Y35-Y36 Legal intervention and operations of war
0.693 0.307 0.000
Y10-Y34 Event of undetermined intent
0.693 0.307 0.000
Y00-Y09 Assault
0.693 0.307 0.000
X85-X99 Assault
0.693 0.307 0.000
X50-X57 Overexertion, travel and privation
0.693 0.307 0.000
X30-X39 Exposure to forces of nature
0.693 0.307 0.000
X20-X29 Contact with venomous animals and plants
0.693 0.307 0.000
X10-X19 Contact with heat and hot substances
0.693 0.307 0.000
X00-X09 Exposure to smoke, fire and flames
0.693 0.307 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.693 0.307 0.000
W75-W84 Other accidental threats to breathing
0.693 0.307 0.000
W65-W74 Accidental drowning and submersion
0.693 0.307 0.000
W50-W64 Exposure to animate mechanical forces
0.693 0.307 0.000
V98-V99 Other and unspecified transport accidents
0.693 0.307 0.000
V95-V97 Air and space transport accidents
0.693 0.307 0.000
V90-V94 Water transport accidents
0.693 0.307 0.000
V70-V79 Bus occupant injured in transport accident
0.693 0.307 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.693 0.307 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.693 0.307 0.000
V40-V49 Car occupant injured in transport accident
0.693 0.307 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.693 0.307 0.000
V01-V09 Pedestrian injured in transport accident
0.693 0.307 0.000
A30-A49 Other bacterial diseases
0.693 0.307 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.692 0.308 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.692 0.308 0.000
G83 Other paralytic syndromes
0.691 0.309 0.000
G70-G73 Diseases of myoneural junction and muscle
0.690 0.309 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.690 0.310 0.000
V10-V19 Pedal cyclist injured in transport accident
0.689 0.311 0.000
F33 Recurrent depressive disorder
0.689 0.311 0.000
Z32 Pregnancy examination and test
0.689 0.311 0.000
H36 Retinal disorders in diseases classified elsewhere
0.688 0.312 0.000
A80-A89 Viral infections of the central nervous system
0.688 0.312 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.687 0.313 0.000
Z33 Pregnant state, incidental
0.687 0.313 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.686 0.314 0.000
E00 Congenital iodine-deficiency syndrome
0.686 0.314 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.686 0.314 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.686 0.314 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.686 0.314 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.686 0.314 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.686 0.314 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.686 0.314 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.686 0.314 0.000
T36 Poisoning by systemic antibiotics
0.686 0.314 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.686 0.314 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.686 0.314 0.000
O84 Multiple delivery
0.685 0.314 0.000
O83 Other assisted single delivery
0.685 0.314 0.000
O81 Single delivery by forceps and vacuum extractor
0.685 0.314 0.000
Z38 Liveborn infants according to place of birth
0.684 0.315 0.000
M41 Scoliosis
0.684 0.316 0.000
M35 Other systemic involvement of connective tissue
0.683 0.317 0.000
T51 Toxic effect of alcohol
0.683 0.317 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.683 0.317 0.000
E04.8 Other specified non-toxic goitre
0.683 0.317 0.000
E04.0 Non-toxic diffuse goitre
0.683 0.317 0.000
H33 Retinal detachments and breaks
0.682 0.318 0.000
G40.8 Other epilepsy
0.681 0.318 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.681 0.318 0.000
G40.5 Special epileptic syndromes
0.681 0.318 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.681 0.318 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.681 0.318 0.000
S50-S59 Injuries to the elbow and forearm
0.681 0.319 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.681 0.319 0.000
M05 Seropositive rheumatoid arthritis
0.680 0.320 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.680 0.320 0.000
E32 Diseases of thymus
0.680 0.320 0.000
E31 Polyglandular dysfunction
0.680 0.320 0.000
E30 Disorders of puberty, not elsewhere classified
0.680 0.320 0.000
E26 Hyperaldosteronism
0.680 0.320 0.000
E25 Adrenogenital disorders
0.680 0.320 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.680 0.320 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.679 0.320 0.000
H61 Other disorders of external ear
0.679 0.321 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.678 0.322 0.000
Q50-Q56 Congenital malformations of genital organs
0.677 0.322 0.000
C34.3 Lower lobe, bronchus or lung
0.677 0.323 0.000
E21.3 Hyperparathyroidism, unspecified
0.677 0.323 0.000
G62.0 Drug-induced polyneuropathy
0.677 0.323 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.676 0.324 0.000
S00-S09 Injuries to the head
0.675 0.325 0.000
B99-B99 Other infectious diseases
0.673 0.326 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.673 0.326 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.673 0.326 0.000
B65-B83 Helminthiases
0.673 0.326 0.000
B50-B64 Protozoal diseases
0.673 0.326 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.673 0.326 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.673 0.326 0.000
A75-A79 Rickettsioses
0.673 0.326 0.000
A70-A74 Other diseases caused by chlamydiae
0.673 0.326 0.000
A65-A69 Other spirochaetal diseases
0.673 0.326 0.000
A20-A28 Certain zoonotic bacterial diseases
0.673 0.326 0.000
A15-A19 Tuberculosis
0.673 0.326 0.000
O62 Abnormalities of forces of labour
0.673 0.327 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.673 0.327 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.673 0.327 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.673 0.327 0.000
O23 Infections of genito-urinary tract in pregnancy
0.673 0.327 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.672 0.328 0.000
M21.1 Varus deformity, not elsewhere classified
0.672 0.328 0.000
F32 Depressive episode
0.672 0.328 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.671 0.329 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.670 0.329 0.000
H65.3 Chronic mucoid otitis media
0.670 0.330 0.000
V20-V29 Motorcycle rider injured in transport accident
0.669 0.331 0.000
J04 Acute laryngitis and tracheitis
0.669 0.331 0.000
O36.6 Maternal care for excessive foetal growth
0.668 0.332 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.668 0.332 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.668 0.332 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.667 0.332 0.000
O36.4 Maternal care for intra-uterine death
0.667 0.332 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.667 0.332 0.000
O36.2 Maternal care for hydrops foetalis
0.667 0.332 0.000
O36.1 Maternal care for other isoimmunisation
0.667 0.332 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.666 0.334 0.000
O46.8 Other antepartum haemorrhage
0.665 0.335 0.000
O46.0 Antepartum haemorrhage with coagulation defect
0.665 0.335 0.000
M13.8 Other specified arthritis
0.664 0.335 0.000
M13.1 Monoarthritis, not elsewhere classified
0.664 0.335 0.000
T93 Sequelae of injuries of lower limb
0.664 0.336 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.663 0.336 0.000
E21.0 Primary hyperparathyroidism
0.664 0.336 0.000
O80.0 Spontaneous vertex delivery
0.664 0.336 0.000
Q60-Q64 Congenital malformations of the urinary system
0.663 0.337 0.000
H35.7 Separation of retinal layers
0.662 0.337 0.000
B49 Unspecified mycosis
0.662 0.338 0.000
G43.8 Other migraine
0.662 0.338 0.000
G43.3 Complicated migraine
0.662 0.338 0.000
G43.2 Status migrainosus
0.662 0.338 0.000
G43.0 Migraine without aura [common migraine]
0.662 0.338 0.000
T91 Sequelae of injuries of neck and trunk
0.662 0.338 0.000
E16 Other disorders of pancreatic internal secretion
0.661 0.339 0.000
O41 Other disorders of amniotic fluid and membranes
0.661 0.339 0.000
O42.9 Premature rupture of membranes, unspecified
0.660 0.340 0.000
G30.8 Other Alzheimer's disease
0.660 0.340 0.000
G30.1 Alzheimer's disease with late onset
0.660 0.340 0.000
O82.1 Delivery by emergency Caesarean section
0.659 0.341 0.000
Z37.9 Outcome of delivery unspecified
0.659 0.341 0.000
Z37.7 Other multiple births, all stillborn
0.659 0.341 0.000
Z37.6 Other multiple births, some liveborn
0.659 0.341 0.000
Z37.5 Other multiple births, all liveborn
0.659 0.341 0.000
Z37.4 Twins, both stillborn
0.659 0.341 0.000
Z37.3 Twins, one liveborn and one stillborn
0.659 0.341 0.000
M43 Other deforming dorsopathies
0.659 0.341 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.659 0.341 0.000
M10 Gout
0.658 0.342 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.658 0.342 0.000
M46 Other inflammatory spondylopathies
0.657 0.343 0.000
M47.2 Other spondylosis with radiculopathy
0.657 0.343 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.656 0.344 0.000
Z36.5 Antenatal screening for isoimmunisation
0.655 0.345 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.655 0.345 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.655 0.345 0.000
Z36.1 Antenatal screening for raised alphafetoprotein level
0.655 0.345 0.000
M24 Other specific joint derangements
0.655 0.345 0.000
M11 Other crystal arthropathies
0.655 0.345 0.000
C15 Malignant neoplasm of oesophagus
0.655 0.345 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.654 0.346 0.000
Y95 Nosocomial condition
0.654 0.346 0.000
M21.4 Flat foot [pes planus] (acquired)
0.653 0.347 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.653 0.347 0.000
H54 Blindness and low vision
0.653 0.347 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.653 0.347 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.652 0.347 0.000
T98 Sequelae of other and unspecified effects of external causes
0.652 0.348 0.000
T95 Sequelae of burns, corrosions and frostbite
0.652 0.348 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.652 0.348 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.652 0.348 0.000
T66-T78 Other and unspecified effects of external causes
0.652 0.348 0.000
E04.9 Non-toxic goitre, unspecified
0.652 0.348 0.000
S20-S29 Injuries to the thorax
0.652 0.348 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.652 0.348 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.651 0.349 0.000
H35.4 Peripheral retinal degeneration
0.651 0.349 0.000
J03 Acute tonsillitis
0.650 0.350 0.000
E22 Hyperfunction of pituitary gland
0.650 0.350 0.000
Z39 Postpartum care and examination
0.649 0.351 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.649 0.351 0.000
M07 Psoriatic and enteropathic arthropathies
0.649 0.351 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.649 0.351 0.000
J84 Other interstitial pulmonary diseases
0.647 0.353 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.647 0.353 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.646 0.354 0.000
G80 Infantile cerebral palsy
0.646 0.354 0.000
M81.8 Other osteoporosis
0.645 0.354 0.000
M81.6 Localised osteoporosis [Lequesne]
0.645 0.354 0.000
M81.5 Idiopathic osteoporosis
0.645 0.354 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.645 0.354 0.000
M81.1 Postoophorectomy osteoporosis
0.645 0.354 0.000
M81.0 Postmenopausal osteoporosis
0.645 0.354 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.645 0.354 0.000
G60 Hereditary and idiopathic neuropathy
0.645 0.355 0.000
G64 Other disorders of peripheral nervous system
0.645 0.355 0.000
E24.9 Cushing's syndrome, unspecified
0.645 0.355 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.644 0.356 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.643 0.356 0.000
O97 Death from sequelae of direct obstetric causes
0.643 0.356 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.643 0.356 0.000
O95 Obstetric death of unspecified cause
0.643 0.356 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.643 0.356 0.000
M94 Other disorders of cartilage
0.643 0.357 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.643 0.357 0.000
M33 Dermatopolymyositis
0.643 0.357 0.000
M32 Systemic lupus erythematosus
0.643 0.357 0.000
M30 Polyarteritis nodosa and related conditions
0.643 0.357 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.643 0.357 0.000
J94 Other pleural conditions
0.643 0.357 0.000
T88.5 Other complications of anaesthesia
0.643 0.357 0.000
W18 Other fall on same level
0.642 0.358 0.000
G90-G99 Other disorders of the nervous system
0.642 0.358 0.000
W29.9 Unspecified place
0.642 0.358 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.640 0.360 0.000
Z65 Problems related to other psychosocial circumstances
0.640 0.360 0.000
Z64 Problems related to certain psychosocial circumstances
0.640 0.360 0.000
Z62 Other problems related to upbringing
0.640 0.360 0.000
Z61 Problems related to negative life events in childhood
0.640 0.360 0.000
Z59 Problems related to housing and economic circumstances
0.640 0.360 0.000
Z56 Problems related to employment and unemployment
0.640 0.360 0.000
Z55 Problems related to education and literacy
0.640 0.360 0.000
G47 Sleep disorders
0.639 0.361 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.639 0.361 0.000
O20.0 Threatened abortion
0.638 0.362 0.000
O73 Retained placenta and membranes, without haemorrhage
0.638 0.362 0.000
W08 Fall involving other furniture
0.637 0.362 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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