TreeWAS – Variant ID: rs813379

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S02 Fracture of skull and facial bones	0.000	0.930	0.070
S02.2 Fracture of nasal bones	0.000	0.931	0.069
S02.20 Fracture of nasal bones (closed)	0.000	0.931	0.069
S02.4 Fracture of malar and maxillary bones	0.000	0.932	0.068
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.933	0.067
S00-S09 Injuries to the head	0.000	0.936	0.064
S01 Open wound of head	0.000	0.937	0.063
S05 Injury of eye and orbit	0.000	0.942	0.058
S01.5 Open wound of lip and oral cavity	0.000	0.945	0.055
S01.8 Open wound of other parts of head	0.000	0.945	0.055
S02.8 Fractures of other skull and facial bones	0.000	0.945	0.055
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.947	0.053
S02.5 Fracture of tooth	0.000	0.947	0.053
S01.9 Open wound of head, part unspecified	0.000	0.948	0.052
S02.7 Multiple fractures involving skull and facial bones	0.000	0.948	0.052
S01.4 Open wound of cheek and temporomandibular area	0.000	0.948	0.052
S02.6 Fracture of mandible	0.000	0.949	0.051
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.949	0.050
S01.1 Open wound of eyelid and periocular area	0.000	0.950	0.050
S02.3 Fracture of orbital floor	0.000	0.950	0.050
S02.1 Fracture of base of skull	0.000	0.951	0.049
S02.21 Fracture of nasal bones (open)	0.000	0.952	0.048
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.000	0.952	0.048
S01.0 Open wound of scalp	0.000	0.953	0.047
S05.8 Other injuries of eye and orbit	0.000	0.953	0.047
S04 Injury of cranial nerves	0.000	0.953	0.046
S06 Intracranial injury	0.000	0.954	0.046
S07 Crushing injury of head	0.000	0.954	0.046
S05.5 Penetrating wound of eyeball with foreign body	0.000	0.954	0.045
S05.4 Penetrating wound of orbit with or without foreign body	0.000	0.955	0.045
S01.3 Open wound of ear	0.000	0.955	0.045
S08 Traumatic amputation of part of head	0.000	0.955	0.045
S02.0 Fracture of vault of skull	0.000	0.956	0.044
S00 Superficial injury of head	0.000	0.956	0.044
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.956	0.043
S01.2 Open wound of nose	0.000	0.957	0.043
S05.6 Penetrating wound of eyeball without foreign body	0.000	0.957	0.043
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.000	0.957	0.043
S05.1 Contusion of eyeball and orbital tissues	0.000	0.957	0.043
S09 Other and unspecified injuries of head	0.000	0.958	0.042
S03 Dislocation, sprain and strain of joints and ligaments of head	0.000	0.958	0.042
S05.7 Avulsion of eye	0.000	0.958	0.042
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.959	0.041
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.000	0.959	0.041
S05.9 Injury of eye and orbit, part unspecified	0.000	0.959	0.040
S02.50 Fracture of tooth (closed)	0.000	0.960	0.040
S02.81 Fractures of other skull and facial bones (open)	0.000	0.960	0.039
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.961	0.039
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.962	0.038
S02.51 Fracture of tooth (open)	0.000	0.962	0.038
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.962	0.037
S02.60 Fracture of mandible (closed)	0.000	0.963	0.037
S06.2 Diffuse brain injury	0.000	0.963	0.037
S02.61 Fracture of mandible (open)	0.000	0.963	0.037
S02.31 Fracture of orbital floor (open)	0.000	0.964	0.036
S01.7 Multiple open wounds of head	0.000	0.964	0.035
S00.8 Superficial injury of other parts of head	0.000	0.965	0.035
S06.1 Traumatic cerebral oedema	0.000	0.965	0.035
S02.10 Fracture of base of skull (closed)	0.000	0.965	0.035
S02.30 Fracture of orbital floor (closed)	0.000	0.965	0.035
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.965	0.035
S00.7 Multiple superficial injuries of head	0.000	0.965	0.035
S00.4 Superficial injury of ear	0.000	0.965	0.035
S00.0 Superficial injury of scalp	0.000	0.965	0.035
S06.9 Intracranial injury, unspecified	0.000	0.966	0.034
S04.5 Injury of facial nerve	0.000	0.966	0.034
S04.9 Injury of unspecified cranial nerve	0.000	0.966	0.033
S04.8 Injury of other cranial nerves	0.000	0.966	0.033
S04.7 Injury of accessory nerve	0.000	0.966	0.033
S04.6 Injury of acoustic nerve	0.000	0.966	0.033
S04.4 Injury of abducent nerve	0.000	0.966	0.033
S04.3 Injury of trigeminal nerve	0.000	0.966	0.033
S04.2 Injury of trochlear nerve	0.000	0.966	0.033
S04.1 Injury of oculomotor nerve	0.000	0.966	0.033
S04.0 Injury of optic nerve and pathways	0.000	0.966	0.033
S06.3 Focal brain injury	0.000	0.966	0.033
S06.4 Epidural haemorrhage	0.000	0.966	0.033
S06.7 Intracranial injury with prolonged coma	0.000	0.966	0.033
S07.9 Crushing injury of head, part unspecified	0.000	0.967	0.033
S07.8 Crushing injury of other parts of head	0.000	0.967	0.033
S07.1 Crushing injury of skull	0.000	0.967	0.033
S07.0 Crushing injury of face	0.000	0.967	0.033
S02.11 Fracture of base of skull (open)	0.000	0.967	0.033
S08.9 Traumatic amputation of unspecified part of head	0.000	0.968	0.032
S08.8 Traumatic amputation of other parts of head	0.000	0.968	0.032
S08.0 Avulsion of scalp	0.000	0.968	0.032
S00.5 Superficial injury of lip and oral cavity	0.000	0.968	0.032
S09.2 Traumatic rupture of ear drum	0.000	0.968	0.031
S08.1 Traumatic amputation of ear	0.000	0.969	0.031
S06.8 Other intracranial injuries	0.000	0.969	0.031
S02.01 Fracture of vault of skull (open)	0.000	0.969	0.030
S09.1 Injury of muscle and tendon of head	0.000	0.969	0.031
S06.0 Concussion	0.000	0.969	0.030
S09.0 Injury of blood vessels of head, not elsewhere classified	0.000	0.969	0.030
S09.8 Other specified injuries of head	0.000	0.969	0.030
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.000	0.970	0.030
S03.4 Sprain and strain of jaw	0.000	0.970	0.030
S03.3 Dislocation of other and unspecified parts of head	0.000	0.970	0.030
S03.0 Dislocation of jaw	0.000	0.970	0.030
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.970	0.030
S06.5 Traumatic subdural haemorrhage	0.000	0.970	0.030
S09.7 Multiple injuries of head	0.000	0.970	0.030
S03.1 Dislocation of septal cartilage of nose	0.000	0.971	0.029
S00.1 Contusion of eyelid and periocular area	0.000	0.972	0.028
S03.2 Dislocation of tooth	0.000	0.972	0.028
S00.3 Superficial injury of nose	0.000	0.972	0.028
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.973	0.027
S09.9 Unspecified injury of head	0.000	0.973	0.027
S00.2 Other superficial injuries of eyelid and periocular area	0.000	0.973	0.027
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.973	0.027
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.973	0.026
S02.00 Fracture of vault of skull (closed)	0.000	0.973	0.026
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.974	0.026
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.974	0.025
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.975	0.025
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.975	0.025
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.976	0.024
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.976	0.024
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.976	0.024
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.976	0.024
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.976	0.024
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.976	0.024
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.978	0.022
S06.01 Concussion (with open intracranial wound)	0.000	0.978	0.022
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.978	0.022
S00.9 Superficial injury of head, part unspecified	0.000	0.980	0.020
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.980	0.019
S06.00 Concussion (without open intracranial wound)	0.000	0.981	0.019
N13.3 Other and unspecified hydronephrosis	0.019	0.981	0.000
N13 Obstructive and reflux uropathy	0.018	0.982	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.982	0.018
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.017	0.983	0.000
N13.4 Hydroureter	0.017	0.983	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.016	0.984	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.015	0.985	0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.015	0.985	0.000
N13.8 Other obstructive and reflux uropathy	0.015	0.985	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.014	0.986	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.013	0.987	0.000
N13.6 Pyonephrosis	0.013	0.987	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.012	0.987	0.000
E27 Other disorders of adrenal gland	0.010	0.990	0.000
E20-E35 Disorders of other endocrine glands	0.010	0.990	0.000
E11.9 Without complications	0.009	0.991	0.000
E22 Hyperfunction of pituitary gland	0.009	0.991	0.000
E87.6 Hypokalaemia	0.009	0.991	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.009	0.991	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.009	0.991	0.000
E27.1 Primary adrenocortical insufficiency	0.008	0.992	0.000
E27.9 Disorder of adrenal gland, unspecified	0.008	0.992	0.000
E27.2 Addisonian crisis	0.008	0.992	0.000
E24 Cushing's syndrome	0.008	0.992	0.000
E11 Non-insulin-dependent diabetes mellitus	0.008	0.992	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.008	0.992	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.008	0.992	0.000
E26 Hyperaldosteronism	0.008	0.992	0.000
E29 Testicular dysfunction	0.008	0.992	0.000
E28 Ovarian dysfunction	0.008	0.992	0.000
K26 Duodenal ulcer	0.008	0.992	0.000
E20 Hypoparathyroidism	0.007	0.992	0.000
E87.5 Hyperkalaemia	0.008	0.992	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.007	0.992	0.000
E23 Hypofunction and other disorders of pituitary gland	0.007	0.993	0.000
E32 Diseases of thymus	0.007	0.993	0.000
E31 Polyglandular dysfunction	0.007	0.993	0.000
E27.5 Adrenomedullary hyperfunction	0.007	0.993	0.000
E27.0 Other adrenocortical overactivity	0.007	0.993	0.000
M54.59 Low back pain (Site unspecified)	0.007	0.993	0.000
E22.0 Acromegaly and pituitary gigantism	0.007	0.993	0.000
E87.0 Hyperosmolality and hypernatraemia	0.007	0.993	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.007	0.993	0.000
E30 Disorders of puberty, not elsewhere classified	0.007	0.993	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.007	0.993	0.000
E10-E14 Diabetes mellitus	0.007	0.993	0.000
E87.3 Alkalosis	0.007	0.993	0.000
E87.2 Acidosis	0.007	0.993	0.000
E11.2 With renal complications	0.007	0.993	0.000
E22.1 Hyperprolactinaemia	0.007	0.993	0.000
C67 Malignant neoplasm of bladder	0.007	0.993	0.000
E22.8 Other hyperfunction of pituitary gland	0.007	0.993	0.000
E27.8 Other specified disorders of adrenal gland	0.007	0.993	0.000
E11.6 With other specified complications	0.007	0.993	0.000
R60.0 Localised oedema	0.000	0.993	0.007
E28.2 Polycystic ovarian syndrome	0.007	0.993	0.000
K26.4 Chronic or unspecified with haemorrhage	0.007	0.993	0.000
E25 Adrenogenital disorders	0.006	0.993	0.000
C67.2 Lateral wall of bladder	0.007	0.993	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.006	0.993	0.000
E26.0 Primary hyperaldosteronism	0.006	0.993	0.000
E04 Other non-toxic goitre	0.007	0.993	0.000
E29.1 Testicular hypofunction	0.006	0.994	0.000
E87.4 Mixed disorder of acid-base balance	0.006	0.994	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.006	0.994	0.000
E24.9 Cushing's syndrome, unspecified	0.006	0.994	0.000
E04.9 Non-toxic goitre, unspecified	0.006	0.994	0.000
C67.9 Bladder, unspecified	0.006	0.994	0.000
E24.2 Drug-induced Cushing's syndrome	0.006	0.994	0.000
E20.9 Hypoparathyroidism, unspecified	0.006	0.994	0.000
E24.0 Pituitary-dependent Cushing's disease	0.006	0.994	0.000
E23.6 Other disorders of pituitary gland	0.006	0.994	0.000
E24.8 Other Cushing's syndrome	0.006	0.994	0.000
E00-E07 Disorders of thyroid gland	0.006	0.994	0.000
E11.0 With coma	0.006	0.994	0.000
E04.1 Non-toxic single thyroid nodule	0.006	0.994	0.000
K26.7 Chronic without haemorrhage or perforation	0.006	0.994	0.000
E34 Other endocrine disorders	0.006	0.994	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.006	0.994	0.000
E24.3 Ectopic ACTH syndrome	0.006	0.994	0.000
E24.1 Nelson's syndrome	0.006	0.994	0.000
E11.3 With ophthalmic complications	0.006	0.994	0.000
K26.3 Acute without haemorrhage or perforation	0.006	0.994	0.000
N20.1 Calculus of ureter	0.006	0.994	0.000
K26.2 Acute with both haemorrhage and perforation	0.006	0.994	0.000
E26.9 Hyperaldosteronism, unspecified	0.006	0.994	0.000
C67.3 Anterior wall of bladder	0.006	0.994	0.000
E26.8 Other hyperaldosteronism	0.006	0.994	0.000
E26.1 Secondary hyperaldosteronism	0.006	0.994	0.000
C67.4 Posterior wall of bladder	0.006	0.994	0.000
E11.8 With unspecified complications	0.006	0.994	0.000
E20.8 Other hypoparathyroidism	0.006	0.994	0.000
E29.8 Other testicular dysfunction	0.006	0.994	0.000
E29.0 Testicular hyperfunction	0.006	0.994	0.000
E28.9 Ovarian dysfunction, unspecified	0.006	0.994	0.000
E28.8 Other ovarian dysfunction	0.006	0.994	0.000
E28.1 Androgen excess	0.006	0.994	0.000
E28.0 Oestrogen excess	0.006	0.994	0.000
E29.9 Testicular dysfunction, unspecified	0.006	0.994	0.000
C67.1 Dome of bladder	0.006	0.994	0.000
E07 Other disorders of thyroid	0.006	0.994	0.000
E20.0 Idiopathic hypoparathyroidism	0.005	0.994	0.000
E31.0 Autoimmune polyglandular failure	0.005	0.994	0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.006	0.994	0.000
E23.1 Drug-induced hypopituitarism	0.005	0.994	0.000
E32.9 Disease of thymus, unspecified	0.005	0.994	0.000
E32.8 Other diseases of thymus	0.005	0.994	0.000
E14 Unspecified diabetes mellitus	0.006	0.994	0.000
E23.0 Hypopituitarism	0.005	0.994	0.000
E50-E64 Other nutritional deficiencies	0.006	0.994	0.000
E23.7 Disorder of pituitary gland, unspecified	0.005	0.994	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.005	0.994	0.000
E32.1 Abscess of thymus	0.005	0.994	0.000
E32.0 Persistent hyperplasia of thymus	0.005	0.994	0.000
E11.5 With peripheral circulatory complications	0.005	0.994	0.000
E23.2 Diabetes insipidus	0.005	0.994	0.000
E31.9 Polyglandular dysfunction, unspecified	0.005	0.994	0.000
E31.8 Other polyglandular dysfunction	0.005	0.994	0.000
E31.1 Polyglandular hyperfunction	0.005	0.994	0.000
E14.9 Without complications	0.005	0.995	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.005	0.995	0.000
E04.0 Non-toxic diffuse goitre	0.005	0.995	0.000
E11.7 With multiple complications	0.005	0.995	0.000
K26.5 Chronic or unspecified with perforation	0.005	0.995	0.000
E11.4 With neurological complications	0.005	0.995	0.000
E20.1 Pseudohypoparathyroidism	0.005	0.995	0.000
E30.9 Disorder of puberty, unspecified	0.005	0.995	0.000
E30.8 Other disorders of puberty	0.005	0.995	0.000
E30.1 Precocious puberty	0.005	0.995	0.000
E30.0 Delayed puberty	0.005	0.995	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.005	0.995	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.005	0.995	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.005	0.995	0.000
K26.1 Acute with perforation	0.005	0.995	0.000
E07.9 Disorder of thyroid, unspecified	0.005	0.995	0.000
E12 Malnutrition-related diabetes mellitus	0.005	0.995	0.000
C67.5 Bladder neck	0.005	0.995	0.000
C67.8 Overlapping lesion of bladder	0.005	0.995	0.000
E11.1 With ketoacidosis	0.005	0.995	0.000
C67.0 Trigone of bladder	0.005	0.995	0.000
E28.3 Primary ovarian failure	0.005	0.995	0.000
C67.7 Urachus	0.005	0.995	0.000
C67.6 Ureteric orifice	0.005	0.995	0.000
N10-N16 Renal tubulo-interstitial diseases	0.005	0.995	0.000
E25.9 Adrenogenital disorder, unspecified	0.005	0.995	0.000
E25.8 Other adrenogenital disorders	0.005	0.995	0.000
E87.7 Fluid overload	0.005	0.995	0.000
E04.8 Other specified non-toxic goitre	0.005	0.995	0.000
E13 Other specified diabetes mellitus	0.005	0.995	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.005	0.995	0.000
E34.8 Other specified endocrine disorders	0.004	0.995	0.000
E65-E68 Obesity and other hyperalimentation	0.005	0.995	0.000
E53 Deficiency of other B group vitamins	0.005	0.995	0.000
E34.3 Short stature, not elsewhere classified	0.004	0.995	0.000
E40-E46 Malnutrition	0.005	0.995	0.000
K26.0 Acute with haemorrhage	0.004	0.995	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.005	0.995	0.000
E00 Congenital iodine-deficiency syndrome	0.005	0.995	0.000
E34.5 Androgen resistance syndrome	0.004	0.995	0.000
E34.4 Constitutional tall stature	0.004	0.995	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.004	0.995	0.000
E34.1 Other hypersecretion of intestinal hormones	0.004	0.995	0.000
E70-E90 Metabolic disorders	0.005	0.995	0.000
Z29.1 Prophylactic immunotherapy	0.005	0.995	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.004	0.995	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.004	0.995	0.000
E07.8 Other specified disorders of thyroid	0.004	0.995	0.000
E56 Other vitamin deficiencies	0.004	0.996	0.000
E14.0 With coma	0.004	0.996	0.000
E34.0 Carcinoid syndrome	0.004	0.996	0.000
E54 Ascorbic acid deficiency	0.004	0.996	0.000
E14.2 Withrenal complications	0.004	0.996	0.000
M54.5 Low back pain	0.004	0.996	0.000
E07.1 Dyshormogenetic goitre	0.004	0.996	0.000
E07.0 Hypersecretion of calcitonin	0.004	0.996	0.000
E58 Dietary calcium deficiency	0.004	0.996	0.000
E14.7 With multiple complications	0.004	0.996	0.000
E16 Other disorders of pancreatic internal secretion	0.004	0.996	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.004	0.996	0.000
E50 Vitamin A deficiency	0.004	0.996	0.000
E60 Dietary zinc deficiency	0.004	0.996	0.000
E59 Dietary selenium deficiency	0.004	0.996	0.000
E52 Niacin deficiency [pellagra]	0.004	0.996	0.000
E14.5 With peripheral circulatory complications	0.004	0.996	0.000
E61 Deficiency of other nutrient elements	0.004	0.996	0.000
E63 Other nutritional deficiencies	0.004	0.996	0.000
E14.4 With neurological complications	0.004	0.996	0.000
E51 Thiamine deficiency	0.004	0.996	0.000
E15 Nondiabetic hypoglycaemic coma	0.004	0.996	0.000
E14.8 With unspecified complications	0.004	0.996	0.000
E14.1 With ketoacidosis	0.004	0.996	0.000
E12.9 Without complications	0.004	0.996	0.000
E12.8 With unspecified complications	0.004	0.996	0.000
E12.7 With multiple complications	0.004	0.996	0.000
E12.6 With other specified complications	0.004	0.996	0.000
E12.5 With peripheral circulatory complications	0.004	0.996	0.000
E12.4 With neurological complications	0.004	0.996	0.000
E12.3 With ophthalmic complications	0.004	0.996	0.000
E12.2 With renal complications	0.004	0.996	0.000
E12.1 With ketoacidosis	0.004	0.996	0.000
E12.0 With coma	0.004	0.996	0.000
E65 Localised adiposity	0.004	0.996	0.000
Z29.2 Other prophylactic chemotherapy	0.004	0.996	0.000
E14.6 With other specified complications	0.004	0.996	0.000
E53.9 Vitamin B deficiency, unspecified	0.004	0.996	0.000
E06 Thyroiditis	0.004	0.996	0.000
E53.8 Deficiency of other specified B group vitamins	0.004	0.996	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.004	0.996	0.000
E10 Insulin-dependent diabetes mellitus	0.004	0.996	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.004	0.996	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.004	0.996	0.000
N10 Acute tubulo-interstitial nephritis	0.004	0.996	0.000
E04.2 Non-toxic multinodular goitre	0.004	0.996	0.000
E13.8 With unspecified complications	0.004	0.996	0.000
E13.7 With multiple complications	0.004	0.996	0.000
E13.6 With other specified complications	0.004	0.996	0.000
E13.5 With peripheral circulatory complications	0.004	0.996	0.000
E13.4 With neurological complications	0.004	0.996	0.000
E13.2 With renal complications	0.004	0.996	0.000
E13.1 With ketoacidosis	0.004	0.996	0.000
E13.0 With coma	0.004	0.996	0.000
Z29 Need for other prophylactic measures	0.004	0.996	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.004	0.996	0.000
Z80.4 Family history of malignant neoplasm of genital organs	0.004	0.996	0.000
E67 Other hyperalimentation	0.004	0.996	0.000
E68 Sequelae of hyperalimentation	0.004	0.996	0.000
E13.9 Without complications	0.004	0.996	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.004	0.996	0.000
E53.1 Pyridoxine deficiency	0.004	0.996	0.000
E53.0 Riboflavin deficiency	0.004	0.996	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.003	0.996	0.000
E45 Retarded development following protein-energy malnutrition	0.003	0.996	0.000
E43 Unspecified severe protein-energy malnutrition	0.003	0.996	0.000
E42 Marasmic kwashiorkor	0.003	0.996	0.000
E41 Nutritional marasmus	0.003	0.996	0.000
E40 Kwashiorkor	0.003	0.996	0.000
E55 Vitamin D deficiency	0.003	0.996	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.003	0.996	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.003	0.996	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.003	0.996	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.003	0.996	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.003	0.996	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.003	0.996	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.003	0.996	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.003	0.996	0.000
E77 Disorders of glycoprotein metabolism	0.004	0.996	0.000
E56.1 Deficiency of vitamin K	0.003	0.996	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.003	0.996	0.000
N11 Chronic tubulo-interstitial nephritis	0.003	0.996	0.000
E70 Disorders of aromatic amino-acid metabolism	0.003	0.996	0.000
E14.3 With ophthalmic complications	0.003	0.996	0.000
E76 Disorders of glycosaminoglycan metabolism	0.003	0.996	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.003	0.996	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.003	0.996	0.000
E13.3 With ophthalmic complications	0.003	0.996	0.000
E72 Other disorders of amino-acid metabolism	0.003	0.996	0.000
N15 Other renal tubulo-interstitial diseases	0.003	0.996	0.000
M54.52 Low back pain-Cervical	0.003	0.996	0.000
E84 Cystic fibrosis	0.003	0.996	0.000
M54.54 Low back pain-Thoracic	0.003	0.997	0.000
E89.3 Postprocedural hypopituitarism	0.003	0.997	0.000
Z83.7 Family history of diseases of the digestive system	0.000	0.997	0.003
M54.56 Low back pain (Lumbar region)	0.003	0.997	0.000
E56.9 Vitamin deficiency, unspecified	0.003	0.997	0.000
E56.8 Deficiency of other vitamins	0.003	0.997	0.000
E56.0 Deficiency of vitamin E	0.003	0.997	0.000
E79 Disorders of purine and pyrimidine metabolism	0.003	0.997	0.000
E73 Lactose intolerance	0.003	0.997	0.000
M54.55 Low back pain (Thoracolumbar region)	0.003	0.997	0.000
M79.66 Pain in limb (Lower leg)	0.003	0.997	0.000
E10.6 With other specified complications	0.003	0.997	0.000
E21.2 Other hyperparathyroidism	0.003	0.997	0.000
E03 Other hypothyroidism	0.003	0.997	0.000
M54.53 Low back pain-Cervicothoracic	0.003	0.997	0.000
M54.51 Low back pain-Occipit-atl-axl	0.003	0.997	0.000
Z29.0 Isolation	0.003	0.997	0.000
E74 Other disorders of carbohydrate metabolism	0.003	0.997	0.000
E50.9 Vitamin A deficiency, unspecified	0.003	0.997	0.000
E50.8 Other manifestations of vitamin A deficiency	0.003	0.997	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.003	0.997	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.003	0.997	0.000
E50.5 Vitamin A deficiency with night blindness	0.003	0.997	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.003	0.997	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.003	0.997	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.003	0.997	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.003	0.997	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.003	0.997	0.000
E61.2 Magnesium deficiency	0.003	0.997	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.003	0.997	0.000
E64.8 Sequelae of other nutritional deficiencies	0.003	0.997	0.000
E64.3 Sequelae of rickets	0.003	0.997	0.000
E64.2 Sequelae of vitamin C deficiency	0.003	0.997	0.000
E64.1 Sequelae of vitamin A deficiency	0.003	0.997	0.000
E64.0 Sequelae of protein-energy malnutrition	0.003	0.997	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.003	0.997	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.003	0.997	0.000
E16.4 Abnormal secretion of gastrin	0.003	0.997	0.000
E16.3 Increased secretion of glucagon	0.003	0.997	0.000
E34.9 Endocrine disorder, unspecified	0.003	0.997	0.001
E61.9 Deficiency of nutrient element, unspecified	0.003	0.997	0.000
E61.8 Deficiency of other specified nutrient elements	0.003	0.997	0.000
E61.7 Deficiency of multiple nutrient elements	0.003	0.997	0.000
E61.6 Vanadium deficiency	0.003	0.997	0.000
E61.5 Molybdenum deficiency	0.003	0.997	0.000
E61.4 Chromium deficiency	0.003	0.997	0.000
E61.3 Manganese deficiency	0.003	0.997	0.000
E61.0 Copper deficiency	0.003	0.997	0.000
E63.8 Other specified nutritional deficiencies	0.003	0.997	0.000
E63.1 Imbalance of constituents of food intake	0.003	0.997	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.003	0.997	0.000
E88 Other metabolic disorders	0.003	0.997	0.000
E51.9 Thiamine deficiency, unspecified	0.003	0.997	0.000
E51.8 Other manifestations of thiamine deficiency	0.003	0.997	0.000
E51.1 Beriberi	0.003	0.997	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.003	0.997	0.000
E63.9 Nutritional deficiency, unspecified	0.003	0.997	0.000
E61.1 Iron deficiency	0.003	0.997	0.000
E16.1 Other hypoglycaemia	0.003	0.997	0.000
E51.2 Wernicke's encephalopathy	0.003	0.997	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.003	0.997	0.000
E10.3 With ophthalmic complications	0.003	0.997	0.000
E06.5 Other chronic thyroiditis	0.003	0.997	0.000
E10.4 With neurological complications	0.003	0.997	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.003	0.997	0.000
E21.4 Other specified disorders of parathyroid gland	0.003	0.997	0.000
K31.8 Other specified diseases of stomach and duodenum	0.000	0.997	0.003
M54.9 Dorsalgia, unspecified	0.003	0.997	0.000
C64-C68 Malignant neoplasms of urinary tract	0.003	0.997	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
E10.5 With peripheral circulatory complications	0.003	0.997	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.003	0.997	0.000
E89.4 Postprocedural ovarian failure	0.003	0.997	0.000
M54.50 Low back pain (Multiple sites in spine)	0.003	0.997	0.000
E06.4 Drug-induced thyroiditis	0.003	0.997	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.003	0.997	0.000
E06.0 Acute thyroiditis	0.003	0.997	0.000
E16.2 Hypoglycaemia, unspecified	0.003	0.997	0.000
E89.5 Postprocedural testicular hypofunction	0.003	0.997	0.000
E06.1 Subacute thyroiditis	0.003	0.997	0.000
E10.2 With renal complications	0.003	0.997	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.003	0.997	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.003	0.997	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.003	0.997	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.003	0.997	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.003	0.997	0.000
E06.9 Thyroiditis, unspecified	0.003	0.997	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.003	0.997	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.003	0.997	0.000
N14.3 Nephropathy induced by heavy metals	0.003	0.997	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.003	0.997	0.000
N14.0 Analgesic nephropathy	0.003	0.997	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.003	0.997	0.000
E89.1 Postprocedural hypoinsulinaemia	0.003	0.997	0.000
E46 Unspecified protein-energy malnutrition	0.003	0.997	0.000
M54.57 Low back pain (Lumbosacral region)	0.003	0.997	0.000
E10.0 With coma	0.003	0.997	0.000
E21.3 Hyperparathyroidism, unspecified	0.003	0.997	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.003	0.997	0.000
Z29.9 Prophylactic measure, unspecified	0.003	0.997	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.003	0.997	0.000
E89.2 Postprocedural hypoparathyroidism	0.003	0.997	0.000
E10.7 With multiple complications	0.003	0.997	0.000
C66 Malignant neoplasm of ureter	0.003	0.997	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.003	0.997	0.000
E67.8 Other specified hyperalimentation	0.003	0.997	0.000
E67.3 Hypervitaminosis D	0.003	0.997	0.000
E67.2 Megavitamin-B6 syndrome	0.003	0.997	0.000
E67.1 Hypercarotenaemia	0.003	0.997	0.000
E67.0 Hypervitaminosis A	0.003	0.997	0.000
E77.8 Other disorders of glycoprotein metabolism	0.003	0.997	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.003	0.997	0.000
M54 Dorsalgia	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations