TreeWAS – Variant ID: rs817300

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.9 Chronic ischaemic heart disease, unspecified	0.207	0.793	0.000
I25 Chronic ischaemic heart disease	0.203	0.797	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.202	0.798	0.000
I25.4 Coronary artery aneurysm	0.169	0.831	0.000
I25.5 Ischaemic cardiomyopathy	0.166	0.834	0.000
I25.3 Aneurysm of heart	0.165	0.835	0.000
I25.2 Old myocardial infarction	0.159	0.841	0.000
I25.6 Silent myocardial ischaemia	0.146	0.854	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.137	0.863	0.000
I20-I25 Ischaemic heart diseases	0.124	0.876	0.000
I20 Angina pectoris	0.115	0.885	0.000
I20.9 Angina pectoris, unspecified	0.113	0.887	0.000
I20.1 Angina pectoris with documented spasm	0.097	0.903	0.000
I23 Certain current complications following acute myocardial infarction	0.095	0.905	0.000
I21 Acute myocardial infarction	0.095	0.905	0.000
I22 Subsequent myocardial infarction	0.090	0.910	0.000
I21.9 Acute myocardial infarction, unspecified	0.086	0.914	0.000
I23.8 Other current complications following acute myocardial infarction	0.073	0.927	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.071	0.929	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.071	0.929	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.070	0.930	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.068	0.932	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.068	0.932	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.068	0.932	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.068	0.932	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.068	0.932	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.068	0.932	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.068	0.932	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.068	0.932	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.068	0.932	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.065	0.935	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.065	0.935	0.000
I20.8 Other forms of angina pectoris	0.065	0.935	0.000
I22.8 Subsequent myocardial infarction of other sites	0.058	0.942	0.000
I21.4 Acute subendocardial myocardial infarction	0.051	0.949	0.000
I25.1 Atherosclerotic heart disease	0.049	0.951	0.000
I24 Other acute ischaemic heart diseases	0.046	0.954	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.044	0.956	0.000
I20.0 Unstable angina	0.035	0.965	0.000
I24.1 Dressler's syndrome	0.033	0.966	0.000
I24.8 Other forms of acute ischaemic heart disease	0.031	0.969	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.022	0.977	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.020	0.980	0.000
N13.3 Other and unspecified hydronephrosis	0.010	0.990	0.000
Q38.7 Pharyngeal pouch	0.009	0.991	0.000
N80.1 Endometriosis of ovary	0.009	0.991	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.008	0.992	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.008	0.992	0.000
N13 Obstructive and reflux uropathy	0.008	0.992	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.008	0.992	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.008	0.992	0.000
N80 Endometriosis	0.007	0.993	0.000
Q43 Other congenital malformations of intestine	0.007	0.993	0.000
N10-N16 Renal tubulo-interstitial diseases	0.007	0.993	0.000
N80.4 Endometriosis of rectovaginal septum and vagina	0.007	0.993	0.000
Q43.0 Meckel's diverticulum	0.007	0.993	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.007	0.993	0.000
Q60-Q64 Congenital malformations of the urinary system	0.007	0.993	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.993	0.007
N80.8 Other endometriosis	0.007	0.993	0.000
N13.4 Hydroureter	0.006	0.994	0.000
N80.5 Endometriosis of intestine	0.006	0.994	0.000
Q63 Other congenital malformations of kidney	0.006	0.994	0.000
Q00-Q07 Congenital malformations of the nervous system	0.006	0.994	0.000
Q38.8 Other congenital malformations of pharynx	0.006	0.994	0.000
Q38.6 Other congenital malformations of mouth	0.006	0.994	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.006	0.994	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.006	0.994	0.000
Q38.3 Other congenital malformations of tongue	0.006	0.994	0.000
Q38.2 Macroglossia	0.006	0.994	0.000
Q38.1 Ankyloglossia	0.006	0.994	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.006	0.994	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.006	0.994	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.006	0.994	0.000
N80.9 Endometriosis, unspecified	0.006	0.994	0.000
Q50-Q56 Congenital malformations of genital organs	0.006	0.994	0.000
N13.8 Other obstructive and reflux uropathy	0.006	0.994	0.000
Q45 Other congenital malformations of digestive system	0.006	0.994	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.006	0.994	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.006	0.994	0.000
Q40 Other congenital malformations of upper alimentary tract	0.006	0.994	0.000
Q39 Congenital malformations of oesophagus	0.006	0.994	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.994	0.006
N10 Acute tubulo-interstitial nephritis	0.006	0.994	0.000
N11 Chronic tubulo-interstitial nephritis	0.006	0.994	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.006	0.994	0.000
N80.3 Endometriosis of pelvic peritoneum	0.006	0.994	0.000
Q61 Cystic kidney disease	0.006	0.994	0.000
Q63.0 Accessory kidney	0.006	0.994	0.000
Q43.8 Other specified congenital malformations of intestine	0.005	0.994	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.005	0.994	0.000
Q51 Congenital malformations of uterus and cervix	0.005	0.994	0.000
N80.6 Endometriosis in cutaneous scar	0.005	0.994	0.000
Q43.7 Persistent cloaca	0.005	0.994	0.000
Q43.6 Congenital fistula of rectum and anus	0.005	0.994	0.000
Q43.5 Ectopic anus	0.005	0.994	0.000
Q43.4 Duplication of intestine	0.005	0.994	0.000
Q43.3 Congenital malformations of intestinal fixation	0.005	0.994	0.000
Q43.2 Other congenital functional disorders of colon	0.005	0.994	0.000
Q43.1 Hirschsprung's disease	0.005	0.994	0.000
Q80-Q89 Other congenital malformations	0.005	0.994	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.005	0.994	0.000
Q05 Spina bifida	0.005	0.994	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.005	0.995	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.005	0.995	0.000
N15 Other renal tubulo-interstitial diseases	0.005	0.995	0.000
Q51.3 Bicornate uterus	0.005	0.995	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.005	0.995	0.000
Q04 Other congenital malformations of brain	0.005	0.995	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.005	0.995	0.000
Q54 Hypospadias	0.005	0.995	0.000
N80.2 Endometriosis of Fallopian tube	0.005	0.995	0.000
R00.1 Bradycardia, unspecified	0.005	0.995	0.000
Q07 Other congenital malformations of nervous system	0.005	0.995	0.000
Q35-Q37 Cleft lip and cleft palate	0.005	0.995	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.005	0.995	0.000
N11.1 Chronic obstructive pyelonephritis	0.005	0.995	0.000
N13.6 Pyonephrosis	0.005	0.995	0.000
Q64 Other congenital malformations of urinary system	0.005	0.995	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.005	0.995	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.005	0.995	0.000
N80.0 Endometriosis of uterus	0.005	0.995	0.000
Q05.9 Spina bifida, unspecified	0.005	0.995	0.000
O36.8 Maternal care for other specified foetal problems	0.005	0.995	0.000
R29.6 Tendency to fall, not elsewhere classified	0.005	0.995	0.000
N28.8 Other specified disorders of kidney and ureter	0.005	0.995	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.005	0.995	0.000
Q63.8 Other specified congenital malformations of kidney	0.005	0.995	0.000
Q63.3 Hyperplastic and giant kidney	0.005	0.995	0.000
Q63.2 Ectopic kidney	0.005	0.995	0.000
Q06 Other congenital malformations of spinal cord	0.005	0.995	0.000
Q03 Congenital hydrocephalus	0.005	0.995	0.000
Q01 Encephalocele	0.005	0.995	0.000
Q00 Anencephaly and similar malformations	0.005	0.995	0.000
Q02 Microcephaly	0.005	0.995	0.000
Q61.2 Polycystic kidney, adult type	0.005	0.995	0.000
Q83 Congenital malformations of breast	0.005	0.995	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.004	0.995	0.000
Q55 Other congenital malformations of male genital organs	0.004	0.995	0.000
Q52 Other congenital malformations of female genitalia	0.004	0.995	0.000
Q53 Undescended testicle	0.004	0.995	0.000
Q85 Phakomatoses, not elsewhere classified	0.004	0.995	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.004	0.995	0.000
Q39.8 Other congenital malformations of oesophagus	0.004	0.995	0.000
Q39.6 Diverticulum of oesophagus	0.004	0.995	0.000
Q39.5 Congenital dilatation of oesophagus	0.004	0.995	0.000
Q39.4 Oesophageal web	0.004	0.995	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.004	0.995	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.004	0.995	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.004	0.995	0.000
Q39.0 Atresia of oesophagus without fistula	0.004	0.995	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.004	0.995	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.004	0.995	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.004	0.995	0.000
Q40.2 Other specified congenital malformations of stomach	0.004	0.995	0.000
Q40.1 Congenital hiatus hernia	0.004	0.995	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.004	0.995	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.004	0.995	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.004	0.995	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.004	0.995	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.004	0.995	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.004	0.995	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.004	0.995	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.004	0.995	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.004	0.995	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.004	0.995	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.004	0.995	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.004	0.995	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.004	0.995	0.000
Q45.8 Other specified congenital malformations of digestive system	0.004	0.995	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.004	0.995	0.000
Q45.2 Congenital pancreatic cyst	0.004	0.995	0.000
Q45.1 Annular pancreas	0.004	0.995	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.004	0.995	0.000
Q54.0 Hypospadias, balanic	0.004	0.995	0.000
Q61.5 Medullary cystic kidney	0.004	0.995	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.004	0.995	0.000
Q04.6 Congenital cerebral cysts	0.004	0.995	0.000
Q61.0 Congenital single renal cyst	0.004	0.996	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.004	0.996	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.004	0.996	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.004	0.996	0.000
Q44.7 Other congenital malformations of liver	0.004	0.996	0.000
Q44.5 Other congenital malformations of bile ducts	0.004	0.996	0.000
Q44.4 Choledochal cyst	0.004	0.996	0.000
Q44.3 Congenital stenosis and stricture of bile ducts	0.004	0.996	0.000
Q44.2 Atresia of bile ducts	0.004	0.996	0.000
Q44.1 Other congenital malformations of gallbladder	0.004	0.996	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.004	0.996	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.004	0.996	0.000
Q61.9 Cystic kidney disease, unspecified	0.004	0.996	0.000
Q61.8 Other cystic kidney diseases	0.004	0.996	0.000
Q61.4 Renal dysplasia	0.004	0.996	0.000
Q61.1 Polycystic kidney, infantile type	0.004	0.996	0.000
M50.3 Other cervical disk degeneration	0.000	0.996	0.004
N14.4 Toxic nephropathy, not elsewhere classified	0.004	0.996	0.000
N14.3 Nephropathy induced by heavy metals	0.004	0.996	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.004	0.996	0.000
N14.0 Analgesic nephropathy	0.004	0.996	0.000
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.004	0.996	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.004	0.996	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.004	0.996	0.000
Q51.6 Embryonic cyst of cervix	0.004	0.996	0.000
Q51.5 Agenesis and aplasia of cervix	0.004	0.996	0.000
Q51.4 Unicornate uterus	0.004	0.996	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.004	0.996	0.000
Q51.0 Agenesis and aplasia of uterus	0.004	0.996	0.000
Q07.0 Arnold-Chiari syndrome	0.004	0.996	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.004	0.996	0.000
Q84 Other congenital malformations of integument	0.004	0.996	0.000
Q81 Epidermolysis bullosa	0.004	0.996	0.000
Q80 Congenital ichthyosis	0.004	0.996	0.000
Q51.2 Other doubling of uterus	0.004	0.996	0.000
Q89 Other congenital malformations, not elsewhere classified	0.004	0.996	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.004	0.996	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.004	0.996	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.004	0.996	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.004	0.996	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.004	0.996	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.004	0.996	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.004	0.996	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.004	0.996	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.004	0.996	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.004	0.996	0.000
Q60.0 Renal agenesis, unilateral	0.004	0.996	0.000
K22.8 Other specified diseases of oesophagus	0.004	0.996	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.004	0.996	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.004	0.996	0.000
N15.1 Renal and perinephric abscess	0.004	0.996	0.000
N15.0 Balkan nephropathy	0.004	0.996	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.004	0.996	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.004	0.996	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.004	0.996	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.004	0.996	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.004	0.996	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.004	0.996	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
Q44.6 Cystic disease of liver	0.004	0.996	0.000
Q61.3 Polycystic kidney, unspecified	0.004	0.996	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.004	0.996	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.004	0.996	0.000
Q96 Turner's syndrome	0.004	0.996	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.004	0.996	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.004	0.996	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.004	0.996	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.004	0.996	0.000
Q90 Down's syndrome	0.004	0.996	0.000
Q54.9 Hypospadias, unspecified	0.004	0.996	0.000
D86.0 Sarcoidosis of lung	0.004	0.996	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.004	0.996	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.004	0.996	0.000
Q12 Congenital lens malformations	0.004	0.996	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.996	0.004
Q04.9 Congenital malformation of brain, unspecified	0.004	0.996	0.000
Q04.8 Other specified congenital malformations of brain	0.004	0.996	0.000
Q04.5 Megalencephaly	0.004	0.996	0.000
Q04.4 Septo-optic dysplasia	0.004	0.996	0.000
Q04.3 Other reduction deformities of brain	0.004	0.996	0.000
Q04.2 Holoprosencephaly	0.004	0.996	0.000
Q04.1 Arhinencephaly	0.004	0.996	0.000
Q04.0 Congenital malformations of corpus callosum	0.004	0.996	0.000
Q60.6 Potter's syndrome	0.004	0.996	0.000
Q60.5 Renal hypoplasia, unspecified	0.004	0.996	0.000
Q60.4 Renal hypoplasia, bilateral	0.004	0.996	0.000
Q60.3 Renal hypoplasia, unilateral	0.004	0.996	0.000
Q60.2 Renal agenesis, unspecified	0.004	0.996	0.000
Q60.1 Renal agenesis, bilateral	0.004	0.996	0.000
Q54.8 Other hypospadias	0.004	0.996	0.000
Q54.4 Congenital chordee	0.004	0.996	0.000
Q54.3 Hypospadias, perineal	0.004	0.996	0.000
Q54.2 Hypospadias, penoscrotal	0.004	0.996	0.000
Q54.1 Hypospadias, penile	0.004	0.996	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.004	0.996	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.004	0.996	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.004	0.996	0.000
Q07.9 Congenital malformation of nervous system, unspecified	0.004	0.996	0.000
Q07.8 Other specified congenital malformations of nervous system	0.004	0.996	0.000
Q34 Other congenital malformations of respiratory system	0.004	0.996	0.000
Q33 Congenital malformations of lung	0.004	0.996	0.000
Q32 Congenital malformations of trachea and bronchus	0.004	0.996	0.000
Q31 Congenital malformations of larynx	0.004	0.996	0.000
Q30 Congenital malformations of nose	0.004	0.996	0.000
Q37 Cleft palate with cleft lip	0.004	0.996	0.000
Q36 Cleft lip	0.004	0.996	0.000
Q35 Cleft palate	0.004	0.996	0.000
Q62.8 Other congenital malformations of ureter	0.004	0.996	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.004	0.996	0.000
Q62.6 Malposition of ureter	0.004	0.996	0.000
Q62.5 Duplication of ureter	0.004	0.996	0.000
Q62.4 Agenesis of ureter	0.004	0.996	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.004	0.996	0.000
Q62.2 Congenital megaloureter	0.004	0.996	0.000
Q62.1 Atresia and stenosis of ureter	0.004	0.996	0.000
Q62.0 Congenital hydronephrosis	0.004	0.996	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.004	0.996	0.000
Q64.8 Other specified congenital malformations of urinary system	0.004	0.996	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.004	0.996	0.000
Q64.6 Congenital diverticulum of bladder	0.004	0.996	0.000
Q64.5 Congenital absence of bladder and urethra	0.004	0.996	0.000
Q64.4 Malformation of urachus	0.004	0.996	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.004	0.996	0.000
Q64.2 Congenital posterior urethral valves	0.004	0.996	0.000
Q64.1 Exstrophy of urinary bladder	0.004	0.996	0.000
Q64.0 Epispadias	0.004	0.996	0.000
Q83.1 Accessory breast	0.004	0.996	0.000
Q17 Other congenital malformations of ear	0.004	0.996	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.004	0.996	0.000
Q15 Other congenital malformations of eye	0.004	0.996	0.000
Q14 Congenital malformations of posterior segment of eye	0.004	0.996	0.000
Q13 Congenital malformations of anterior segment of eye	0.004	0.996	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.004	0.996	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.004	0.996	0.000
Q83.8 Other congenital malformations of breast	0.004	0.996	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.003	0.996	0.000
Q82 Other congenital malformations of skin	0.004	0.996	0.000
Q00.2 Iniencephaly	0.003	0.996	0.000
Q00.1 Craniorachischisis	0.003	0.996	0.000
Q00.0 Anencephaly	0.003	0.996	0.000
Q01.9 Encephalocele, unspecified	0.003	0.996	0.000
Q01.8 Encephalocele of other sites	0.003	0.996	0.000
Q01.2 Occipital encephalocele	0.003	0.996	0.000
Q01.1 Nasofrontal encephalocele	0.003	0.996	0.000
Q01.0 Frontal encephalocele	0.003	0.996	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.003	0.996	0.000
Q03.8 Other congenital hydrocephalus	0.003	0.996	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.003	0.996	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.003	0.996	0.000
Q06.9 Congenital malformation of spinal cord, unspecified	0.003	0.996	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.003	0.996	0.000
Q06.4 Hydromyelia	0.003	0.996	0.000
Q06.3 Other congenital cauda equina malformations	0.003	0.996	0.000
Q06.2 Diastematomyelia	0.003	0.996	0.000
Q06.1 Hypoplasia and dysplasia of spinal cord	0.003	0.996	0.000
Q06.0 Amyelia	0.003	0.996	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.004	0.996	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.003	0.996	0.000
Q83.9 Congenital malformation of breast, unspecified	0.003	0.996	0.000
Q83.3 Accessory nipple	0.003	0.996	0.000
Q83.2 Absent nipple	0.003	0.996	0.000
Q83.0 Congenital absence of breast with absent nipple	0.003	0.996	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.003	0.996	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.003	0.996	0.000
Q52.7 Other congenital malformations of vulva	0.003	0.996	0.000
Q52.6 Congenital malformation of clitoris	0.003	0.996	0.000
Q52.5 Fusion of labia	0.003	0.996	0.000
Q52.4 Other congenital malformations of vagina	0.003	0.996	0.000
Q52.3 Imperforate hymen	0.003	0.996	0.000
Q52.2 Congenital rectovaginal fistula	0.003	0.996	0.000
Q52.1 Doubling of vagina	0.003	0.996	0.000
Q52.0 Congenital absence of vagina	0.003	0.996	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.003	0.996	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.003	0.996	0.000
Q55.6 Other congenital malformations of penis	0.003	0.996	0.000
Q55.5 Congenital absence and aplasia of penis	0.003	0.996	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.003	0.996	0.000
Q55.3 Atresia of vas deferens	0.003	0.996	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.003	0.996	0.000
Q55.1 Hypoplasia of testis and scrotum	0.003	0.996	0.000
Q55.0 Absence and aplasia of testis	0.003	0.996	0.000
Q56.4 Indeterminate sex, unspecified	0.003	0.996	0.000
Q56.3 Pseudohermaphroditism, unspecified	0.003	0.996	0.000
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.003	0.996	0.000
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.003	0.996	0.000
Q56.0 Hermaphroditism, not elsewhere classified	0.003	0.996	0.000
B02 Zoster [herpes zoster]	0.004	0.996	0.000
Q53.9 Undescended testicle, unspecified	0.003	0.996	0.000
Q53.2 Undescended testicle, bilateral	0.003	0.996	0.000
Q53.0 Ectopic testis	0.003	0.996	0.000
B00 Herpesviral [herpes simplex] infections	0.004	0.996	0.000
Q25 Congenital malformations of great arteries	0.003	0.996	0.000
B02.9 Zoster without complication	0.004	0.996	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.000	0.996	0.004
Q53.1 Undescended testicle, unilateral	0.003	0.996	0.000
Q85.9 Phakomatosis, unspecified	0.003	0.996	0.000
Q85.1 Tuberous sclerosis	0.003	0.996	0.000
Q87.4 Marfan's syndrome	0.003	0.996	0.000
B00.1 Herpesviral vesicular dermatitis	0.003	0.997	0.000
Q18 Other congenital malformations of face and neck	0.003	0.997	0.000
B00.9 Herpesviral infection, unspecified	0.003	0.997	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.997	0.003
B02.2 Zoster with other nervous system involvement	0.003	0.997	0.000
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.003	0.997	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.003	0.997	0.000
Q98.7 Male with sex chromosome mosaicism	0.003	0.997	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.003	0.997	0.000
Q98.5 Karyotype 47,XYY	0.003	0.997	0.000
Q98.3 Other male with 46,XX karyotype	0.003	0.997	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.003	0.997	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.003	0.997	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.003	0.997	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.003	0.997	0.000
Q12.0 Congenital cataract	0.003	0.997	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.003	0.997	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.003	0.997	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.003	0.997	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.003	0.997	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.003	0.997	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.003	0.997	0.000
Q80.9 Congenital ichthyosis, unspecified	0.003	0.997	0.000
Q80.8 Other congenital ichthyosis	0.003	0.997	0.000
Q80.4 Harlequin foetus	0.003	0.997	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.003	0.997	0.000
Q80.2 Lamellar ichthyosis	0.003	0.997	0.000
Q80.1 X-linked ichthyosis	0.003	0.997	0.000
Q80.0 Ichthyosis vulgaris	0.003	0.997	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.003	0.997	0.000
Q81.8 Other epidermolysis bullosa	0.003	0.997	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.003	0.997	0.000
Q81.1 Epidermolysis bullosa letalis	0.003	0.997	0.000
Q81.0 Epidermolysis bullosa simplex	0.003	0.997	0.000
Q84.9 Congenital malformation of integument, unspecified	0.003	0.997	0.000
Q84.8 Other specified congenital malformations of integument	0.003	0.997	0.000
Q84.6 Other congenital malformations of nails	0.003	0.997	0.000
Q84.5 Enlarged and hypertrophic nails	0.003	0.997	0.000
Q84.4 Congenital leukonychia	0.003	0.997	0.000
Q84.3 Anonychia	0.003	0.997	0.000
Q84.2 Other congenital malformations of hair	0.003	0.997	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.003	0.997	0.000
Q84.0 Congenital alopecia	0.003	0.997	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.003	0.997	0.000
Q86.2 Dysmorphism due to warfarin	0.003	0.997	0.000
Q86.1 Foetal hydantoin syndrome	0.003	0.997	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.003	0.997	0.000
O36 Maternal care for other known or suspected foetal problems	0.003	0.997	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.003	0.997	0.000
Q89.9 Congenital malformation, unspecified	0.003	0.997	0.000
Q89.8 Other specified congenital malformations	0.003	0.997	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.003	0.997	0.000
Q89.4 Conjoined twins	0.003	0.997	0.000
Q89.3 Situs inversus	0.003	0.997	0.000
Q89.1 Congenital malformations of adrenal gland	0.003	0.997	0.000
Q89.0 Congenital malformations of spleen	0.003	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
Q24 Other congenital malformations of heart	0.003	0.997	0.000
Q89.2 Congenital malformations of other endocrine glands	0.003	0.997	0.000
Q90.9 Down's syndrome, unspecified	0.003	0.997	0.000
Q90.2 Trisomy 21, translocation	0.003	0.997	0.000
Q90.1 Trisomy 21, mosaicism (mitotic nondisjunction)	0.003	0.997	0.000
Q90.0 Trisomy 21, meiotic nondisjunction	0.003	0.997	0.000
Q91.7 Patau's syndrome, unspecified	0.003	0.997	0.000
Q91.6 Trisomy 13, translocation	0.003	0.997	0.000
Q91.5 Trisomy 13, mosaicism (mitotic nondisjunction)	0.003	0.997	0.000
Q91.4 Trisomy 13, meiotic nondisjunction	0.003	0.997	0.000
Q91.3 Edwards' syndrome, unspecified	0.003	0.997	0.000
Q91.2 Trisomy 18, translocation	0.003	0.997	0.000
Q91.1 Trisomy 18, mosaicism (mitotic nondisjunction)	0.003	0.997	0.000
Q91.0 Trisomy 18, meiotic nondisjunction	0.003	0.997	0.000
Q92.9 Trisomy and partial trisomy of autosomes, unspecified	0.003	0.997	0.000
Q92.8 Other specified trisomies and partial trisomies of autosomes	0.003	0.997	0.000
Q92.7 Triploidy and polyploidy	0.003	0.997	0.000
Q92.6 Extra marker chromosomes	0.003	0.997	0.000
Q92.5 Duplications with other complex rearrangements	0.003	0.997	0.000
Q92.4 Duplications seen only at prometaphase	0.003	0.997	0.000
Q92.3 Minor partial trisomy	0.003	0.997	0.000
Q92.2 Major partial trisomy	0.003	0.997	0.000
Q92.1 Whole chromosome trisomy, mosaicism (mitotic nondisjunction)	0.003	0.997	0.000
Q92.0 Whole chromosome trisomy, meiotic nondisjunction	0.003	0.997	0.000
Q93.9 Deletion from autosomes, unspecified	0.003	0.997	0.000
Q93.8 Other deletions from the autosomes	0.003	0.997	0.000
Q93.7 Deletions with other complex rearrangements	0.003	0.997	0.000
Q93.6 Deletions seen only at prometaphase	0.003	0.997	0.000
Q93.5 Other deletions of part of a chromosome	0.003	0.997	0.000
Q93.4 Deletion of short arm of chromosome 5	0.003	0.997	0.000
Q93.3 Deletion of short arm of chromosome 4	0.003	0.997	0.000
Q93.2 Chromosome replaced with ring or dicentric	0.003	0.997	0.000
Q93.1 Whole chromosome monosomy, mosaicism (mitotic nondisjunction)	0.003	0.997	0.000
Q93.0 Whole chromosome monosomy, meiotic nondisjunction	0.003	0.997	0.000
Q95.9 Balanced rearrangement and structural marker, unspecified	0.003	0.997	0.000
Q95.8 Other balanced rearrangements and structural markers	0.003	0.997	0.000
Q95.5 Individuals with autosomal fragile site	0.003	0.997	0.000
Q95.4 Individuals with marker heterochromatin	0.003	0.997	0.000
Q95.3 Balanced sex/autosomal rearrangement in abnormal individual	0.003	0.997	0.000
Q95.2 Balanced autosomal rearrangement in abnormal individual	0.003	0.997	0.000
Q95.1 Chromosome inversion in normal individual	0.003	0.997	0.000
Q95.0 Balanced translocation and insertion in normal individual	0.003	0.997	0.000
Q96.9 Turner's syndrome, unspecified	0.003	0.997	0.000
Q96.8 Other variants of Turner's syndrome	0.003	0.997	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.003	0.997	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.003	0.997	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.003	0.997	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.003	0.997	0.000
Q96.0 Karyotype 45,X	0.003	0.997	0.000
Q97.9 Sex chromosome abnormality, female phenotype, unspecified	0.003	0.997	0.000
Q97.8 Other specified sex chromosome abnormalities, female phenotype	0.003	0.997	0.000
Q97.3 Female with 46,XY karyotype	0.003	0.997	0.000
Q97.2 Mosaicism, lines with various numbers of X chromosomes	0.003	0.997	0.000
Q97.1 Female with more than three X chromosomes	0.003	0.997	0.000
Q97.0 Karyotype 47,XXX	0.003	0.997	0.000
Q99.9 Chromosomal abnormality, unspecified	0.003	0.997	0.000
Q99.8 Other specified chromosome abnormalities	0.003	0.997	0.000
Q99.2 Fragile X chromosome	0.003	0.997	0.000
Q99.1 46,XX true hermaphrodite	0.003	0.997	0.000
Q99.0 Chimera 46,XX/46,XY	0.003	0.997	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.003	0.997	0.000
Q26 Congenital malformations of great veins	0.003	0.997	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.003	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.003	0.997	0.000
Q12.9 Congenital lens malformation, unspecified	0.003	0.997	0.000
Q12.8 Other congenital lens malformations	0.003	0.997	0.000
Q12.4 Spherophakia	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations