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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs886425
log Bayes Factor = 133.047
Chromosome 6   position 30,781,301  (GRCh37) Explore rs886425 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
1.000 0.000 0.000
E05.9 Thyrotoxicosis, unspecified
1.000 0.000 0.000
E05.0 Thyrotoxicosis with diffuse goitre
1.000 0.000 0.000
E10.9 Without complications
1.000 0.000 0.000
E10.3 With ophthalmic complications
1.000 0.000 0.000
H36.0 Diabetic retinopathy
1.000 0.000 0.000
M35.0 Sicca syndrome [Sjogren]
1.000 0.000 0.000
E05 Thyrotoxicosis [hyperthyroidism]
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
R31 Unspecified haematuria
0.000 0.000 1.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
E00-E07 Disorders of thyroid gland
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
K70-K77 Diseases of liver
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
E16.2 Hypoglycaemia, unspecified
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
E03 Other hypothyroidism
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
E16 Other disorders of pancreatic internal secretion
1.000 0.000 0.000
E14 Unspecified diabetes mellitus
1.000 0.000 0.000
H36 Retinal disorders in diseases classified elsewhere
1.000 0.000 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
1.000 0.000 0.000
K75 Other inflammatory liver diseases
1.000 0.000 0.000
D60-D64 Aplastic and other anaemias
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
M35 Other systemic involvement of connective tissue
1.000 0.000 0.000
I73 Other peripheral vascular diseases
0.999 0.001 0.000
J40-J47 Chronic lower respiratory diseases
0.999 0.001 0.000
D80-D89 Certain disorders involving the immune mechanism
0.999 0.001 0.000
M20-M25 Other joint disorders
0.999 0.001 0.000
K75.4 Autoimmune hepatitis
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
D64 Other anaemias
0.998 0.002 0.000
E14.3 With ophthalmic complications
0.998 0.002 0.000
D64.9 Anaemia, unspecified
0.998 0.002 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.998 0.002 0.000
D50-D53 Nutritional anaemias
0.997 0.003 0.000
K74 Fibrosis and cirrhosis of liver
0.997 0.003 0.000
B35-B49 Mycoses
0.997 0.003 0.000
J44 Other chronic obstructive pulmonary disease
0.996 0.004 0.000
J45 Asthma
0.996 0.004 0.000
I74 Arterial embolism and thrombosis
0.996 0.004 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.996 0.004 0.000
I73.9 Peripheral vascular disease, unspecified
0.995 0.005 0.000
E10.1 With ketoacidosis
0.995 0.005 0.000
J45.9 Asthma, unspecified
0.995 0.005 0.000
D86 Sarcoidosis
0.994 0.006 0.000
E11.3 With ophthalmic complications
0.994 0.006 0.000
Chapter VI Diseases of the nervous system
0.992 0.008 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.992 0.008 0.000
B37 Candidiasis
0.992 0.008 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.992 0.008 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.992 0.008 0.000
N00-N08 Glomerular diseases
0.991 0.009 0.000
Chapter XIV Diseases of the genitourinary system
0.991 0.009 0.000
I77 Other disorders of arteries and arterioles
0.990 0.010 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.990 0.010 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.989 0.011 0.000
D50 Iron deficiency anaemia
0.989 0.011 0.000
N17-N19 Renal failure
0.989 0.011 0.000
N18 Chronic renal failure
0.989 0.011 0.000
K72 Hepatic failure, not elsewhere classified
0.988 0.012 0.000
D86.9 Sarcoidosis, unspecified
0.988 0.012 0.000
Chapter XX External causes of morbidity and mortality
0.988 0.012 0.000
E10.2 With renal complications
0.988 0.012 0.000
I60-I69 Cerebrovascular diseases
0.987 0.013 0.000
K74.6 Other and unspecified cirrhosis of liver
0.986 0.014 0.000
E50-E64 Other nutritional deficiencies
0.985 0.015 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.985 0.015 0.000
B37.9 Candidiasis, unspecified
0.985 0.015 0.000
H43-H45 Disorders of vitreous body and globe
0.984 0.016 0.000
E20-E35 Disorders of other endocrine glands
0.984 0.016 0.000
G35 Multiple sclerosis
0.983 0.017 0.000
E11.9 Without complications
0.982 0.018 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.980 0.020 0.000
E27.1 Primary adrenocortical insufficiency
0.980 0.020 0.000
I63 Cerebral infarction
0.980 0.020 0.000
E27 Other disorders of adrenal gland
0.980 0.020 0.000
H34 Retinal vascular occlusions
0.980 0.020 0.000
Chapter XI Diseases of the digestive system
0.978 0.021 0.001
K75.8 Other specified inflammatory liver diseases
0.978 0.022 0.000
H43 Disorders of vitreous body
0.975 0.025 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.975 0.025 0.000
J33 Nasal polyp
0.974 0.026 0.000
I73.0 Raynaud's syndrome
0.974 0.026 0.000
J33.0 Polyp of nasal cavity
0.973 0.027 0.000
J30-J39 Other diseases of upper respiratory tract
0.972 0.028 0.000
I77.1 Stricture of artery
0.971 0.029 0.000
D50.9 Iron deficiency anaemia, unspecified
0.970 0.030 0.000
A30-A49 Other bacterial diseases
0.970 0.030 0.000
N40 Hyperplasia of prostate
0.000 0.030 0.970
H43.1 Vitreous haemorrhage
0.970 0.030 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.968 0.032 0.000
N18.0 End-stage renal disease
0.967 0.033 0.000
C83.3 Large cell (diffuse)
0.966 0.034 0.000
C15-C26 Malignant neoplasms of digestive organs
0.966 0.034 0.000
A41 Other septicaemia
0.963 0.037 0.000
R30-R39 Symptoms and signs involving the urinary system
0.000 0.038 0.962
L92 Granulomatous disorders of skin and subcutaneous tissue
0.962 0.038 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.962 0.038 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.961 0.039 0.000
D61 Other aplastic anaemias
0.960 0.040 0.000
N05 Unspecified nephritic syndrome
0.960 0.040 0.000
K72.0 Acute and subacute hepatic failure
0.958 0.042 0.000
H34.8 Other retinal vascular occlusions
0.958 0.042 0.000
B15-B19 Viral hepatitis
0.957 0.043 0.000
A41.9 Septicaemia, unspecified
0.957 0.043 0.000
C85.1 B-cell lymphoma, unspecified
0.957 0.043 0.000
E53 Deficiency of other B group vitamins
0.956 0.044 0.000
E06 Thyroiditis
0.955 0.045 0.000
E11.5 With peripheral circulatory complications
0.954 0.046 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.954 0.046 0.000
L10-L14 Bullous disorders
0.952 0.048 0.000
K73 Chronic hepatitis, not elsewhere classified
0.952 0.048 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.950 0.050 0.000
R39 Other symptoms and signs involving the urinary system
0.000 0.050 0.950
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.000 0.051 0.949
J84 Other interstitial pulmonary diseases
0.949 0.051 0.000
M20.1 Hallux valgus (acquired)
0.000 0.052 0.948
N18.3 Chronic kidney disease, stage 3
0.947 0.053 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.947 0.053 0.000
I77.6 Arteritis, unspecified
0.945 0.055 0.000
R30 Pain associated with micturition
0.000 0.059 0.941
E53.8 Deficiency of other specified B group vitamins
0.938 0.062 0.000
E70-E90 Metabolic disorders
0.938 0.062 0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue
0.938 0.062 0.000
N04 Nephrotic syndrome
0.938 0.062 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.936 0.064 0.000
E89.0 Postprocedural hypothyroidism
0.935 0.065 0.000
C16 Malignant neoplasm of stomach
0.935 0.065 0.000
B37.8 Candidiasis of other sites
0.935 0.065 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.931 0.069 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.931 0.069 0.000
C34 Malignant neoplasm of bronchus and lung
0.930 0.070 0.000
R30.0 Dysuria
0.000 0.073 0.927
E14.9 Without complications
0.926 0.074 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.920 0.080 0.000
C34.3 Lower lobe, bronchus or lung
0.920 0.080 0.000
E10.4 With neurological complications
0.917 0.083 0.000
L13 Other bullous disorders
0.917 0.083 0.000
L50-L54 Urticaria and erythema
0.915 0.085 0.000
K90-K93 Other diseases of the digestive system
0.914 0.086 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.913 0.087 0.000
W00-W19 Falls
0.913 0.087 0.000
M70-M79 Other soft tissue disorders
0.911 0.089 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.910 0.090 0.000
K72.9 Hepatic failure, unspecified
0.910 0.090 0.000
E06.3 Autoimmune thyroiditis
0.910 0.090 0.000
K90 Intestinal malabsorption
0.910 0.090 0.000
L94 Other localised connective tissue disorders
0.910 0.090 0.000
D61.9 Aplastic anaemia, unspecified
0.910 0.090 0.000
G30-G32 Other degenerative diseases of the nervous system
0.909 0.091 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.907 0.093 0.000
I62 Other nontraumatic intracranial haemorrhage
0.906 0.094 0.000
E11.1 With ketoacidosis
0.905 0.095 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.904 0.096 0.000
B44 Aspergillosis
0.903 0.097 0.000
C81 Hodgkin's disease
0.902 0.098 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.902 0.098 0.000
D51 Vitamin B12 deficiency anaemia
0.902 0.098 0.000
B25-B34 Other viral diseases
0.901 0.099 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.900 0.100 0.000
M72 Fibroblastic disorders
0.900 0.100 0.000
I63.8 Other cerebral infarction
0.900 0.100 0.000
K73.2 Chronic active hepatitis, not elsewhere classified
0.896 0.104 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.895 0.105 0.000
J46 Status asthmaticus
0.894 0.106 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.894 0.106 0.000
N18.9 Chronic renal failure, unspecified
0.894 0.106 0.000
L13.0 Dermatitis herpetiformis
0.892 0.108 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.891 0.109 0.000
K70 Alcoholic liver disease
0.891 0.109 0.000
B18 Chronic viral hepatitis
0.890 0.110 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.888 0.112 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.885 0.115 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.885 0.115 0.000
W19 Unspecified fall
0.885 0.115 0.000
D80 Immunodeficiency with predominantly antibody defects
0.884 0.116 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.884 0.116 0.000
N05.2 Diffuse membranous glomerulonephritis
0.883 0.117 0.000
D69 Purpura and other haemorrhagic conditions
0.883 0.117 0.000
K90.9 Intestinal malabsorption, unspecified
0.882 0.118 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.881 0.119 0.000
C92 Myeloid leukaemia
0.881 0.119 0.000
B02 Zoster [herpes zoster]
0.878 0.122 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.878 0.122 0.000
M34 Systemic sclerosis
0.878 0.122 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.875 0.125 0.000
C04 Malignant neoplasm of floor of mouth
0.875 0.125 0.000
N04.9 Unspecified
0.874 0.126 0.000
C91 Lymphoid leukaemia
0.872 0.128 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.867 0.133 0.000
V20-V29 Motorcycle rider injured in transport accident
0.867 0.133 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.867 0.133 0.000
K74.3 Primary biliary cirrhosis
0.867 0.133 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.867 0.133 0.000
D83 Common variable immunodeficiency
0.862 0.138 0.000
J33.8 Other polyp of sinus
0.862 0.138 0.000
B25 Cytomegaloviral disease
0.862 0.138 0.000
M35.3 Polymyalgia rheumatica
0.861 0.139 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.857 0.143 0.000
J37 Chronic laryngitis and laryngotracheitis
0.855 0.145 0.000
K76 Other diseases of liver
0.854 0.146 0.000
E14.8 With unspecified complications
0.853 0.147 0.000
E24 Cushing's syndrome
0.853 0.147 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.853 0.147 0.000
M86-M90 Other osteopathies
0.853 0.147 0.000
M24 Other specific joint derangements
0.852 0.148 0.000
G81 Hemiplegia
0.851 0.149 0.000
E10.5 With peripheral circulatory complications
0.850 0.150 0.000
I71 Aortic aneurysm and dissection
0.850 0.150 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.849 0.151 0.000
N18.8 Other chronic renal failure
0.849 0.151 0.000
E13 Other specified diabetes mellitus
0.845 0.155 0.000
H05 Disorders of orbit
0.843 0.157 0.000
J33.9 Nasal polyp, unspecified
0.843 0.157 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.842 0.158 0.000
I10-I15 Hypertensive diseases
0.842 0.158 0.000
N08.5 Glomerular disorders in systemic connective tissue disorders
0.840 0.160 0.000
M32 Systemic lupus erythematosus
0.840 0.160 0.000
D86.0 Sarcoidosis of lung
0.840 0.160 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.839 0.161 0.000
C16.9 Stomach, unspecified
0.839 0.161 0.000
H06.2 Dysthyroid exophthalmos
0.839 0.161 0.000
B18.2 Chronic viral hepatitis C
0.839 0.161 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.838 0.162 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.838 0.162 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.837 0.163 0.000
E55 Vitamin D deficiency
0.836 0.164 0.000
M60-M63 Disorders of muscles
0.834 0.166 0.000
E11.0 With coma
0.833 0.167 0.000
E14.2 Withrenal complications
0.831 0.169 0.000
G81.9 Hemiplegia, unspecified
0.830 0.170 0.000
L52 Erythema nodosum
0.829 0.171 0.000
H34.2 Other retinal artery occlusions
0.829 0.171 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.828 0.172 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.828 0.172 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.826 0.174 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.826 0.174 0.000
H30 Chorioretinal inflammation
0.825 0.175 0.000
D50.8 Other iron deficiency anaemias
0.824 0.176 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.824 0.176 0.000
G51 Facial nerve disorders
0.824 0.176 0.000
J39 Other diseases of upper respiratory tract
0.824 0.176 0.000
E10.8 With unspecified complications
0.822 0.178 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.821 0.179 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.821 0.179 0.000
C92.0 Acute myeloid leukaemia
0.821 0.179 0.000
I74.8 Embolism and thrombosis of other arteries
0.820 0.180 0.000
K74.5 Biliary cirrhosis, unspecified
0.820 0.180 0.000
C88 Malignant immunoproliferative diseases
0.819 0.181 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.819 0.181 0.000
B25.9 Cytomegaloviral disease, unspecified
0.815 0.185 0.000
E11.7 With multiple complications
0.815 0.185 0.000
I95 Hypotension
0.815 0.185 0.000
C25 Malignant neoplasm of pancreas
0.815 0.185 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.814 0.186 0.000
E14.1 With ketoacidosis
0.814 0.186 0.000
W19.2 School, other institution and public administrative area
0.812 0.188 0.000
X10-X19 Contact with heat and hot substances
0.810 0.190 0.000
W19.9 Unspecified place
0.810 0.190 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.809 0.191 0.000
M86 Osteomyelitis
0.808 0.192 0.000
B02.9 Zoster without complication
0.807 0.193 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.807 0.193 0.000
L92.0 Granuloma annulare
0.807 0.193 0.000
M20 Acquired deformities of fingers and toes
0.003 0.194 0.804
V01-V09 Pedestrian injured in transport accident
0.806 0.194 0.000
L53 Other erythematous conditions
0.806 0.194 0.000
K74.0 Hepatic fibrosis
0.805 0.195 0.000
H46 Optic neuritis
0.804 0.196 0.000
B16 Acute hepatitis B
0.803 0.197 0.000
I12 Hypertensive renal disease
0.803 0.197 0.000
N00 Acute nephritic syndrome
0.803 0.197 0.000
C16.8 Overlapping lesion of stomach
0.801 0.199 0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis
0.801 0.199 0.000
E10.7 With multiple complications
0.799 0.201 0.000
W05 Fall involving wheelchair
0.799 0.201 0.000
K76.6 Portal hypertension
0.799 0.201 0.000
K70.9 Alcoholic liver disease, unspecified
0.798 0.202 0.000
E51 Thiamine deficiency
0.797 0.203 0.000
C31 Malignant neoplasm of accessory sinuses
0.797 0.203 0.000
E10.0 With coma
0.797 0.203 0.000
H05.2 Exophthalmic conditions
0.796 0.204 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.795 0.205 0.000
D50.1 Sideropenic dysphagia
0.794 0.206 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.794 0.206 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.793 0.207 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.792 0.208 0.000
J95-J99 Other diseases of the respiratory system
0.791 0.209 0.000
N05.8 Other
0.790 0.210 0.000
C16.3 Pyloric antrum
0.790 0.210 0.000
E11.6 With other specified complications
0.790 0.210 0.000
E14.6 With other specified complications
0.789 0.211 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.789 0.211 0.000
V40-V49 Car occupant injured in transport accident
0.786 0.213 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.786 0.214 0.000
K73.9 Chronic hepatitis, unspecified
0.785 0.215 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.785 0.215 0.000
C18 Malignant neoplasm of colon
0.784 0.216 0.000
L94.2 Calcinosis cutis
0.782 0.218 0.000
D55-D59 Haemolytic anaemias
0.782 0.218 0.000
B01 Varicella [chickenpox]
0.782 0.218 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.781 0.219 0.000
B44.9 Aspergillosis, unspecified
0.781 0.219 0.000
M22 Disorders of patella
0.780 0.220 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.780 0.220 0.000
X20-X29 Contact with venomous animals and plants
0.780 0.220 0.000
Y42.7 Androgens and anabolic congeners
0.780 0.220 0.000
J41 Simple and mucopurulent chronic bronchitis
0.778 0.222 0.000
E10.6 With other specified complications
0.777 0.223 0.000
H43.2 Crystalline deposits in vitreous body
0.776 0.224 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.776 0.224 0.000
D70 Agranulocytosis
0.775 0.225 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.773 0.227 0.000
E03.8 Other specified hypothyroidism
0.773 0.227 0.000
I12.9 Hypertensive renal disease without renal failure
0.773 0.227 0.000
D69.4 Other primary thrombocytopenia
0.772 0.228 0.000
C10 Malignant neoplasm of oropharynx
0.772 0.228 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.772 0.228 0.000
Y52 Agents primarily affecting the cardiovascular system
0.771 0.229 0.000
N18.1 Chronic kidney disease, stage 1
0.771 0.229 0.000
J37.0 Chronic laryngitis
0.770 0.230 0.000
M35.7 Hypermobility syndrome
0.770 0.230 0.000
C23 Malignant neoplasm of gallbladder
0.770 0.230 0.000
K76.9 Liver disease, unspecified
0.770 0.230 0.000
N05.1 Focal and segmental glomerular lesions
0.768 0.232 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.768 0.232 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.768 0.232 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.768 0.232 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.767 0.233 0.000
C22.0 Liver cell carcinoma
0.767 0.233 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.767 0.233 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.766 0.234 0.000
B17 Other acute viral hepatitis
0.766 0.234 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.766 0.234 0.000
M20.5 Other deformities of toe(s) (acquired)
0.000 0.234 0.766
G70-G73 Diseases of myoneural junction and muscle
0.764 0.235 0.000
E31 Polyglandular dysfunction
0.764 0.236 0.000
B44.1 Other pulmonary aspergillosis
0.764 0.236 0.000
A65-A69 Other spirochaetal diseases
0.764 0.236 0.000
M34.1 CR(E)ST syndrome
0.764 0.236 0.000
D83.9 Common variable immunodeficiency, unspecified
0.764 0.236 0.000
G31.8 Other specified degenerative diseases of nervous system
0.764 0.236 0.000
L93 Lupus erythematosus
0.764 0.236 0.000
E06.9 Thyroiditis, unspecified
0.763 0.236 0.000
D53 Other nutritional anaemias
0.762 0.238 0.000
B37.2 Candidiasis of skin and nail
0.762 0.238 0.000
D86.3 Sarcoidosis of skin
0.761 0.239 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.759 0.241 0.000
D61.0 Constitutional aplastic anaemia
0.759 0.241 0.000
G50 Disorders of trigeminal nerve
0.758 0.242 0.000
G51.9 Disorder of facial nerve, unspecified
0.757 0.243 0.000
D69.6 Thrombocytopenia, unspecified
0.756 0.244 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.756 0.244 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.756 0.244 0.000
B35 Dermatophytosis
0.756 0.244 0.000
N18.4 Chronic kidney disease, stage 4
0.756 0.244 0.000
C83.0 Small cell (diffuse)
0.755 0.244 0.000
C02.9 Tongue, unspecified
0.755 0.245 0.000
I00-I02 Acute rheumatic fever
0.755 0.245 0.000
D80.1 Nonfamilial hypogammaglobulinaemia
0.754 0.246 0.000
G31.0 Circumscribed brain atrophy
0.754 0.246 0.000
C07 Malignant neoplasm of parotid gland
0.754 0.246 0.000
C22.9 Liver, unspecified
0.753 0.247 0.000
D61.1 Drug-induced aplastic anaemia
0.753 0.247 0.000
E07 Other disorders of thyroid
0.753 0.247 0.000
C04.0 Anterior floor of mouth
0.752 0.248 0.000
I74.5 Embolism and thrombosis of iliac artery
0.751 0.249 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.751 0.249 0.000
D69.5 Secondary thrombocytopenia
0.750 0.250 0.000
C04.9 Floor of mouth, unspecified
0.749 0.251 0.000
R30.1 Vesical tenesmus
0.000 0.251 0.749
V90-V94 Water transport accidents
0.749 0.251 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.748 0.252 0.000
J84.8 Other specified interstitial pulmonary diseases
0.748 0.252 0.000
D69.9 Haemorrhagic condition, unspecified
0.748 0.252 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.747 0.253 0.000
I69 Sequelae of cerebrovascular disease
0.746 0.253 0.000
C11 Malignant neoplasm of nasopharynx
0.746 0.254 0.000
N04.2 Diffuse membranous glomerulonephritis
0.746 0.254 0.000
I95.1 Orthostatic hypotension
0.746 0.254 0.000
C16.2 Body of stomach
0.746 0.254 0.000
G56 Mononeuropathies of upper limb
0.746 0.254 0.000
X00-X09 Exposure to smoke, fire and flames
0.745 0.255 0.000
C81.9 Hodgkin's disease, unspecified
0.745 0.255 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.744 0.256 0.000
A15-A19 Tuberculosis
0.743 0.257 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.743 0.257 0.000
C83.1 Small cleaved cell (diffuse)
0.742 0.258 0.000
E14.5 With peripheral circulatory complications
0.742 0.258 0.000
B37.0 Candidal stomatitis
0.741 0.259 0.000
C34.0 Main bronchus
0.741 0.259 0.000
K70.0 Alcoholic fatty liver
0.741 0.259 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.740 0.260 0.000
G56.0 Carpal tunnel syndrome
0.740 0.260 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.739 0.261 0.000
L83 Acanthosis nigricans
0.739 0.261 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.738 0.262 0.000
E20 Hypoparathyroidism
0.737 0.263 0.000
C91.1 Chronic lymphocytic leukaemia
0.736 0.264 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.736 0.264 0.000
I27 Other pulmonary heart diseases
0.736 0.264 0.000
N25-N29 Other disorders of kidney and ureter
0.734 0.266 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.734 0.266 0.000
E73 Lactose intolerance
0.734 0.266 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.733 0.267 0.000
W75-W84 Other accidental threats to breathing
0.732 0.268 0.000
M86.9 Osteomyelitis, unspecified
0.732 0.268 0.000
D69.2 Other nonthrombocytopenic purpura
0.732 0.268 0.000
M31 Other necrotising vasculopathies
0.732 0.268 0.000
M00-M03 Infectious arthropathies
0.732 0.268 0.000
H43.9 Disorder of vitreous body, unspecified
0.732 0.268 0.000
D64.8 Other specified anaemias
0.730 0.270 0.000
E58 Dietary calcium deficiency
0.730 0.270 0.000
Y66 Nonadministration of surgical and medical care
0.730 0.270 0.000
D52 Folate deficiency anaemia
0.730 0.270 0.000
I77.8 Other specified disorders of arteries and arterioles
0.729 0.271 0.000
E55.9 Vitamin D deficiency, unspecified
0.729 0.271 0.000
W13 Fall from, out of or through building or structure
0.727 0.273 0.000
C25.9 Pancreas, unspecified
0.727 0.273 0.000
I95.2 Hypotension due to drugs
0.727 0.273 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.726 0.274 0.000
C91.9 Lymphoid leukaemia, unspecified
0.726 0.274 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.726 0.274 0.000
M33 Dermatopolymyositis
0.725 0.274 0.000
Y48 Anaesthetics and therapeutic gases
0.725 0.275 0.000
C13 Malignant neoplasm of hypopharynx
0.724 0.276 0.000
M65-M68 Disorders of synovium and tendon
0.723 0.277 0.000
A41.2 Septicaemia due to unspecified staphylococcus
0.723 0.277 0.000
C81.2 Mixed cellularity
0.723 0.277 0.000
W20-W49 Exposure to inanimate mechanical forces
0.722 0.278 0.000
E88 Other metabolic disorders
0.722 0.278 0.000
D84 Other immunodeficiencies
0.722 0.278 0.000
B02.2 Zoster with other nervous system involvement
0.722 0.278 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.722 0.278 0.000
C93 Monocytic leukaemia
0.721 0.279 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.721 0.279 0.000
H43.8 Other disorders of vitreous body
0.721 0.279 0.000
C16.6 Greater curvature of stomach, unspecified
0.721 0.279 0.000
E24.2 Drug-induced Cushing's syndrome
0.720 0.279 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.720 0.280 0.000
N04.1 Focal and segmental glomerular lesions
0.719 0.281 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.719 0.281 0.000
K90.8 Other intestinal malabsorption
0.719 0.281 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.719 0.281 0.000
R35 Polyuria
0.000 0.282 0.718
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.718 0.282 0.000
Q50-Q56 Congenital malformations of genital organs
0.718 0.282 0.000
L94.0 Localised scleroderma [morphea]
0.718 0.282 0.000
C83.7 Burkitt's tumour
0.718 0.282 0.000
E05.5 Thyroid crisis or storm
0.717 0.283 0.000
E05.4 Thyrotoxicosis factitia
0.717 0.283 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.717 0.283 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.717 0.283 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.717 0.283 0.000
E00 Congenital iodine-deficiency syndrome
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
K77 Liver disorders in diseases classified elsewhere
0.717 0.283 0.000
K71 Toxic liver disease
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E03.5 Myxoedema coma
0.717 0.283 0.000
E03.4 Atrophy of thyroid (acquired)
0.717 0.283 0.000
E03.3 Postinfectious hypothyroidism
0.717 0.283 0.000
E03.1 Congenital hypothyroidism without goitre
0.717 0.283 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.717 0.283 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.717 0.283 0.000
E16.4 Abnormal secretion of gastrin
0.717 0.283 0.000
E16.3 Increased secretion of glucagon
0.717 0.283 0.000
E14.7 With multiple complications
0.717 0.283 0.000
E14.0 With coma
0.717 0.283 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.717 0.283 0.000
E15 Nondiabetic hypoglycaemic coma
0.717 0.283 0.000
K75.2 Nonspecific reactive hepatitis
0.717 0.283 0.000
K75.1 Phlebitis of portal vein
0.717 0.283 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
C94 Other leukaemias of specified cell type
0.717 0.283 0.000
C86 Other specified types of T/NK-cell lymphoma
0.717 0.283 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.717 0.283 0.000
M35.8 Other specified systemic involvement of connective tissue
0.717 0.283 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.717 0.283 0.000
M35.5 Multifocal fibrosclerosis
0.717 0.283 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.717 0.283 0.000
N17 Acute renal failure
0.717 0.283 0.000
L12 Pemphigoid
0.717 0.283 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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