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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9267576
log Bayes Factor = 125.094
Chromosome 6   position 31,812,038  (GRCh37) Explore rs9267576 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E78.0 Pure hypercholesterolaemia
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
G35 Multiple sclerosis
1.000 0.000 0.000
I10 Essential (primary) hypertension
0.000 0.000 1.000
L40 Psoriasis
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
I10-I15 Hypertensive diseases
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
L40.9 Psoriasis, unspecified
0.000 0.000 1.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.000 1.000
Chapter IX Diseases of the circulatory system
0.000 0.000 1.000
E11.9 Without complications
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
G35-G37 Demyelinating diseases of the central nervous system
1.000 0.000 0.000
E03 Other hypothyroidism
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
L40.5 Arthropathic psoriasis
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
# Top node
0.000 0.000 1.000
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
M06 Other rheumatoid arthritis
0.000 0.000 1.000
M05-M14 Inflammatory polyarthropathies
0.000 0.001 0.999
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.001 0.999
H36.0 Diabetic retinopathy
0.000 0.001 0.999
G37 Other demyelinating diseases of central nervous system
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.002 0.998
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.002 0.998
H36 Retinal disorders in diseases classified elsewhere
0.000 0.002 0.998
L40-L45 Papulosquamous disorders
0.000 0.002 0.998
H30-H36 Disorders of choroid and retina
0.000 0.002 0.998
I20.9 Angina pectoris, unspecified
0.000 0.003 0.997
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.003 0.997
E10.4 With neurological complications
0.000 0.004 0.996
Chapter VII Diseases of the eye and adnexa
0.000 0.004 0.996
E14.9 Without complications
0.000 0.004 0.996
G37.9 Demyelinating disease of central nervous system, unspecified
0.996 0.004 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.005 0.995
E70-E90 Metabolic disorders
0.000 0.006 0.994
E16.2 Hypoglycaemia, unspecified
0.000 0.007 0.993
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.008 0.992
I22 Subsequent myocardial infarction
0.000 0.008 0.992
J45.9 Asthma, unspecified
0.000 0.011 0.989
L43 Lichen planus
0.000 0.011 0.989
Chapter VI Diseases of the nervous system
0.985 0.015 0.000
I25.1 Atherosclerotic heart disease
0.000 0.015 0.985
I20.0 Unstable angina
0.000 0.015 0.985
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.016 0.984
E14.3 With ophthalmic complications
0.000 0.016 0.984
H43-H45 Disorders of vitreous body and globe
0.000 0.017 0.983
G20-G26 Extrapyramidal and movement disorders
0.983 0.017 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.017 0.983
G20 Parkinson's disease
0.982 0.018 0.000
H43 Disorders of vitreous body
0.000 0.020 0.980
L43.9 Lichen planus, unspecified
0.000 0.021 0.979
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.031 0.969
M45-M49 Spondylopathies
0.000 0.035 0.965
M45 Ankylosing spondylitis
0.000 0.037 0.963
H43.8 Other disorders of vitreous body
0.000 0.037 0.963
I25.5 Ischaemic cardiomyopathy
0.000 0.038 0.962
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.040 0.960
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.041 0.959
M05 Seropositive rheumatoid arthritis
0.000 0.054 0.946
I12 Hypertensive renal disease
0.000 0.057 0.943
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.058 0.942
H35 Other retinal disorders
0.000 0.065 0.935
H43.3 Other vitreous opacities
0.000 0.071 0.929
I24 Other acute ischaemic heart diseases
0.000 0.075 0.925
E07 Other disorders of thyroid
0.000 0.078 0.922
E83 Disorders of mineral metabolism
0.900 0.079 0.021
E10.5 With peripheral circulatory complications
0.000 0.082 0.918
M70-M79 Other soft tissue disorders
0.000 0.085 0.915
E78.2 Mixed hyperlipidaemia
0.000 0.091 0.909
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.092 0.908
E11.1 With ketoacidosis
0.000 0.093 0.907
H35.8 Other specified retinal disorders
0.000 0.095 0.905
M07 Psoriatic and enteropathic arthropathies
0.000 0.098 0.902
I12.9 Hypertensive renal disease without renal failure
0.000 0.099 0.901
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.101 0.899
I15 Secondary hypertension
0.000 0.103 0.897
H34 Retinal vascular occlusions
0.000 0.107 0.893
G37.8 Other specified demyelinating diseases of central nervous system
0.891 0.109 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.115 0.885
I30-I52 Other forms of heart disease
0.000 0.118 0.882
I47 Paroxysmal tachycardia
0.000 0.119 0.881
I20.1 Angina pectoris with documented spasm
0.000 0.119 0.881
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.120 0.880
E10.2 With renal complications
0.000 0.121 0.879
G30-G32 Other degenerative diseases of the nervous system
0.874 0.126 0.000
I25.2 Old myocardial infarction
0.000 0.127 0.873
E13 Other specified diabetes mellitus
0.000 0.128 0.872
M75 Shoulder lesions
0.000 0.128 0.872
K90 Intestinal malabsorption
0.000 0.128 0.872
I47.1 Supraventricular tachycardia
0.000 0.136 0.864
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.137 0.863
E07.9 Disorder of thyroid, unspecified
0.000 0.138 0.862
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.142 0.858
M75.0 Adhesive capsulitis of shoulder
0.000 0.145 0.855
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.146 0.854
E11.3 With ophthalmic complications
0.000 0.147 0.853
E78.8 Other disorders of lipoprotein metabolism
0.000 0.149 0.851
M06.3 Rheumatoid nodule
0.000 0.155 0.845
E83.3 Disorders of phosphorus metabolism
0.837 0.158 0.005
G80-G83 Cerebral palsy and other paralytic syndromes
0.840 0.160 0.000
K90-K93 Other diseases of the digestive system
0.000 0.164 0.836
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.164 0.836
Chapter XI Diseases of the digestive system
0.000 0.166 0.834
M07.3 Other psoriatic arthropathies
0.000 0.167 0.833
K70-K77 Diseases of liver
0.000 0.172 0.828
K74 Fibrosis and cirrhosis of liver
0.000 0.176 0.824
I15.1 Hypertension secondary to other renal disorders
0.000 0.176 0.824
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.177 0.823
E74 Other disorders of carbohydrate metabolism
0.000 0.183 0.817
E11.2 With renal complications
0.000 0.184 0.816
K74.3 Primary biliary cirrhosis
0.000 0.188 0.812
M70 Soft tissue disorders related to use, overuse and pressure
0.000 0.189 0.811
I51 Complications and ill-defined descriptions of heart disease
0.000 0.189 0.811
I35 Nonrheumatic aortic valve disorders
0.000 0.189 0.811
L40.8 Other psoriasis
0.000 0.192 0.808
E11.0 With coma
0.000 0.192 0.808
E11.5 With peripheral circulatory complications
0.000 0.195 0.805
I35.0 Aortic (valve) stenosis
0.000 0.195 0.805
I51.8 Other ill-defined heart diseases
0.000 0.197 0.803
E83.5 Disorders of calcium metabolism
0.801 0.198 0.001
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.199 0.801
M77 Other enthesopathies
0.000 0.207 0.793
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.207 0.793
L43.8 Other lichen planus
0.000 0.211 0.789
I47.2 Ventricular tachycardia
0.000 0.211 0.789
M65-M68 Disorders of synovium and tendon
0.000 0.214 0.786
G30 Alzheimer's disease
0.784 0.216 0.000
E78.4 Other hyperlipidaemia
0.000 0.218 0.782
E13.9 Without complications
0.000 0.219 0.781
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.220 0.780
M11 Other crystal arthropathies
0.000 0.220 0.780
M75.2 Bicipital tendinitis
0.000 0.224 0.776
H43.9 Disorder of vitreous body, unspecified
0.000 0.225 0.775
E06 Thyroiditis
0.000 0.228 0.772
E78.1 Pure hyperglyceridaemia
0.000 0.232 0.767
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.234 0.766
J45 Asthma
0.000 0.239 0.761
M70.4 Prepatellar bursitis
0.000 0.240 0.760
H35.6 Retinal haemorrhage
0.000 0.242 0.758
H30 Chorioretinal inflammation
0.000 0.247 0.753
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.248 0.752
G25 Other extrapyramidal and movement disorders
0.751 0.249 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.251 0.749
K72 Hepatic failure, not elsewhere classified
0.000 0.253 0.747
G00-G09 Inflammatory diseases of the central nervous system
0.746 0.254 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.254 0.746
H34.2 Other retinal artery occlusions
0.000 0.255 0.745
M06.4 Inflammatory polyarthropathy
0.000 0.256 0.744
H34.8 Other retinal vascular occlusions
0.000 0.256 0.744
I23 Certain current complications following acute myocardial infarction
0.000 0.257 0.743
H35.2 Other proliferative retinopathy
0.000 0.258 0.742
I25.3 Aneurysm of heart
0.000 0.259 0.741
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.260 0.740
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.740 0.260 0.000
M77.1 Lateral epicondylitis
0.000 0.260 0.740
E05.9 Thyrotoxicosis, unspecified
0.000 0.261 0.739
I46 Cardiac arrest
0.000 0.263 0.737
H35.5 Hereditary retinal dystrophy
0.000 0.263 0.737
E40-E46 Malnutrition
0.000 0.265 0.734
E14.4 With neurological complications
0.000 0.266 0.734
H35.4 Peripheral retinal degeneration
0.000 0.268 0.732
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.273 0.727
I11 Hypertensive heart disease
0.000 0.273 0.727
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.274 0.726
M70.46 Prepatellar bursitis-Lower Leg
0.000 0.276 0.724
L40.0 Psoriasis vulgaris
0.000 0.277 0.723
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.278 0.722
M06.34 Rheumatoid nodule (Hand)
0.000 0.279 0.721
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.279 0.721
K74.5 Biliary cirrhosis, unspecified
0.000 0.279 0.721
G30.9 Alzheimer's disease, unspecified
0.717 0.283 0.000
E10.8 With unspecified complications
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
L40.4 Guttate psoriasis
0.000 0.283 0.717
L40.2 Acrodermatitis continua
0.000 0.283 0.717
L40.1 Generalised pustular psoriasis
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
I13 Hypertensive heart and renal disease
0.000 0.283 0.717
I00-I02 Acute rheumatic fever
0.000 0.283 0.717
E11.7 With multiple complications
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
G36 Other acute disseminated demyelination
0.717 0.283 0.000
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.717 0.283 0.000
E14.8 With unspecified complications
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.6 With other specified complications
0.000 0.283 0.717
E14.5 With peripheral circulatory complications
0.000 0.283 0.717
E14.2 Withrenal complications
0.000 0.283 0.717
E14.1 With ketoacidosis
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.283 0.717
M06.8 Other specified rheumatoid arthritis
0.000 0.283 0.717
M06.2 Rheumatoid bursitis
0.000 0.283 0.717
M06.1 Adult-onset Still's disease
0.000 0.283 0.717
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.283 0.716
M08 Juvenile arthritis
0.000 0.283 0.716
G37.5 Concentric sclerosis [Balo]
0.716 0.284 0.000
G37.4 Subacute necrotising myelitis
0.716 0.284 0.000
G37.2 Central pontine myelinolysis
0.716 0.284 0.000
G37.1 Central demyelination of corpus callosum
0.716 0.284 0.000
G37.0 Diffuse sclerosis
0.716 0.284 0.000
E78.6 Lipoprotein deficiency
0.000 0.284 0.716
E78.3 Hyperchylomicronaemia
0.000 0.284 0.716
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.284 0.716
L44 Other papulosquamous disorders
0.000 0.284 0.715
L41 Parapsoriasis
0.000 0.284 0.715
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.284 0.715
H32 Chorioretinal disorders in diseases classified elsewhere
0.000 0.285 0.715
E15 Nondiabetic hypoglycaemic coma
0.000 0.285 0.715
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.287 0.713
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.287 0.713
E16.4 Abnormal secretion of gastrin
0.000 0.287 0.713
E16.3 Increased secretion of glucagon
0.000 0.287 0.713
E16.1 Other hypoglycaemia
0.000 0.287 0.713
M65 Synovitis and tenosynovitis
0.000 0.287 0.713
E77 Disorders of glycoprotein metabolism
0.000 0.287 0.713
E76 Disorders of glycosaminoglycan metabolism
0.000 0.287 0.713
E72 Other disorders of amino-acid metabolism
0.000 0.287 0.713
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.287 0.713
E70 Disorders of aromatic amino-acid metabolism
0.000 0.287 0.713
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.287 0.713
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.288 0.712
M14 Arthropathies in other diseases classified elsewhere
0.000 0.291 0.709
L43.3 Subacute (active) lichen planus
0.000 0.291 0.709
L43.2 Lichenoid drug reaction
0.000 0.291 0.709
L43.1 Bullous lichen planus
0.000 0.291 0.709
L43.0 Hypertrophic lichen planus
0.000 0.291 0.709
E03.8 Other specified hypothyroidism
0.000 0.292 0.707
G83 Other paralytic syndromes
0.707 0.293 0.000
I45 Other conduction disorders
0.000 0.293 0.707
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.000 0.295 0.705
G23 Other degenerative diseases of basal ganglia
0.705 0.295 0.000
G21 Secondary Parkinsonism
0.705 0.295 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.705 0.295 0.000
G22 Parkinsonism in diseases classified elsewhere
0.705 0.295 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.000 0.297 0.703
H43.2 Crystalline deposits in vitreous body
0.000 0.298 0.702
H43.0 Vitreous prolapse
0.000 0.298 0.702
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.299 0.701
K74.6 Other and unspecified cirrhosis of liver
0.000 0.299 0.701
J40-J47 Chronic lower respiratory diseases
0.000 0.299 0.701
K73 Chronic hepatitis, not elsewhere classified
0.000 0.299 0.701
E11.6 With other specified complications
0.000 0.300 0.700
E79 Disorders of purine and pyrimidine metabolism
0.000 0.303 0.696
I25.4 Coronary artery aneurysm
0.000 0.303 0.696
H35.7 Separation of retinal layers
0.000 0.304 0.696
I05-I09 Chronic rheumatic heart diseases
0.000 0.305 0.695
Chapter X Diseases of the respiratory system
0.000 0.305 0.695
M75.3 Calcific tendinitis of shoulder
0.000 0.305 0.695
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.309 0.691
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.309 0.691
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.309 0.691
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.309 0.691
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.309 0.691
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.309 0.691
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.309 0.691
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.309 0.691
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.309 0.691
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.310 0.690
I12.0 Hypertensive renal disease with renal failure
0.000 0.312 0.688
M49 Spondylopathies in diseases classified elsewhere
0.000 0.315 0.685
M06.0 Seronegative rheumatoid arthritis
0.000 0.317 0.683
L42 Pityriasis rosea
0.000 0.318 0.682
E07.8 Other specified disorders of thyroid
0.000 0.319 0.681
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.321 0.678
M05.8 Other seropositive rheumatoid arthritis
0.000 0.321 0.678
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.321 0.678
M05.2 Rheumatoid vasculitis
0.000 0.321 0.678
M05.1 Rheumatoid lung disease
0.000 0.321 0.678
M05.0 Felty's syndrome
0.000 0.321 0.678
I47.0 Reentry ventricular arrhythmia
0.000 0.323 0.677
G81 Hemiplegia
0.676 0.324 0.000
H34.1 Central retinal artery occlusion
0.000 0.324 0.676
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.001 0.325 0.674
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.326 0.674
M12 Other specific arthropathies
0.000 0.329 0.671
H35.1 Retinopathy of prematurity
0.000 0.329 0.670
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.000 0.333 0.667
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.000 0.333 0.667
M46 Other inflammatory spondylopathies
0.000 0.337 0.663
I46.9 Cardiac arrest, unspecified
0.000 0.338 0.662
E07.1 Dyshormogenetic goitre
0.000 0.339 0.661
E07.0 Hypersecretion of calcitonin
0.000 0.339 0.661
E83.9 Disorder of mineral metabolism, unspecified
0.645 0.340 0.015
E83.8 Other disorders of mineral metabolism
0.645 0.340 0.015
E83.2 Disorders of zinc metabolism
0.645 0.340 0.015
E83.0 Disorders of copper metabolism
0.645 0.340 0.015
M75.4 Impingement syndrome of shoulder
0.000 0.342 0.658
M73 Soft tissue disorders in diseases classified elsewhere
0.000 0.344 0.656
K75 Other inflammatory liver diseases
0.000 0.346 0.654
L40.3 Pustulosis palmaris et plantaris
0.000 0.347 0.653
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.349 0.651
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.349 0.651
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.349 0.651
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.349 0.651
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.349 0.651
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.349 0.651
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.349 0.651
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.349 0.651
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.351 0.649
M07.6 Other enteropathic arthropathies
0.000 0.353 0.647
M07.5 Arthropathy in ulcerative colitis
0.000 0.353 0.647
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.353 0.647
M07.2 Psoriatic spondylitis
0.000 0.353 0.647
M07.1 Arthritis mutilans
0.000 0.353 0.647
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.353 0.647
E84 Cystic fibrosis
0.001 0.356 0.643
I15.9 Seconday hypertension, unspecified
0.000 0.357 0.643
I15.8 Other secondary hypertension
0.000 0.357 0.643
I15.2 Hypertension secondary to endocrine disorders
0.000 0.357 0.643
I15.0 Renovascular hypertension
0.000 0.357 0.643
K72.9 Hepatic failure, unspecified
0.000 0.357 0.643
H31 Other disorders of choroid
0.000 0.357 0.642
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.642 0.358 0.000
H34.9 Retinal vascular occlusion, unspecified
0.000 0.360 0.640
H34.0 Transient retinal artery occlusion
0.000 0.360 0.640
E11.8 With unspecified complications
0.000 0.360 0.640
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.361 0.639
I51.0 Cardiac septal defect, acquired
0.000 0.362 0.638
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.637 0.363 0.000
J86 Pyothorax
0.000 0.364 0.636
E06.3 Autoimmune thyroiditis
0.000 0.365 0.635
H40-H42 Glaucoma
0.000 0.365 0.635
M96.0 Pseudarthrosis after fusion or arthrodesis
0.000 0.365 0.635
I52 Other heart disorders in diseases classified elsewhere
0.000 0.367 0.632
I48 Atrial fibrillation and flutter
0.000 0.367 0.632
I41 Myocarditis in diseases classified elsewhere
0.000 0.367 0.632
I40 Acute myocarditis
0.000 0.367 0.632
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.367 0.632
I32 Pericarditis in diseases classified elsewhere
0.000 0.367 0.632
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.370 0.630
K72.0 Acute and subacute hepatic failure
0.000 0.371 0.629
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)
0.000 0.372 0.628
I45.1 Other and unspecified right bundle-branch block
0.000 0.373 0.627
E13.8 With unspecified complications
0.000 0.375 0.625
E13.7 With multiple complications
0.000 0.375 0.625
E13.6 With other specified complications
0.000 0.375 0.625
E13.5 With peripheral circulatory complications
0.000 0.375 0.625
E13.4 With neurological complications
0.000 0.375 0.625
E13.3 With ophthalmic complications
0.000 0.375 0.625
E13.2 With renal complications
0.000 0.375 0.625
E13.1 With ketoacidosis
0.000 0.375 0.625
E13.0 With coma
0.000 0.375 0.625
M75.8 Other shoulder lesions
0.000 0.375 0.625
K90.3 Pancreatic steatorrhoea
0.000 0.375 0.625
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.375 0.625
K90.1 Tropical sprue
0.000 0.375 0.625
G83.4 Cauda equina syndrome
0.623 0.377 0.000
M11.2 Other chondrocalcinosis
0.000 0.378 0.622
I51.6 Cardiovascular disease, unspecified
0.000 0.378 0.622
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.381 0.619
I45.2 Bifascicular block
0.000 0.382 0.618
H43.1 Vitreous haemorrhage
0.000 0.382 0.618
Q50-Q56 Congenital malformations of genital organs
0.000 0.384 0.616
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.385 0.615
G00 Bacterial meningitis, not elsewhere classified
0.615 0.385 0.000
M77.5 Other enthesopathy of foot
0.000 0.385 0.615
K50-K52 Noninfective enteritis and colitis
0.022 0.389 0.588
L10-L14 Bullous disorders
0.000 0.390 0.610
J46 Status asthmaticus
0.000 0.391 0.609
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.394 0.606
M06.38 Rheumatoid nodule (Other)
0.000 0.394 0.606
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.394 0.606
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.394 0.606
M06.33 Rheumatoid nodule (Forearm)
0.000 0.394 0.606
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.394 0.606
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.394 0.606
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.394 0.606
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.401 0.599
E05.5 Thyroid crisis or storm
0.000 0.401 0.599
E05.4 Thyrotoxicosis factitia
0.000 0.401 0.599
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.401 0.599
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.401 0.599
K90.9 Intestinal malabsorption, unspecified
0.000 0.401 0.599
G30.8 Other Alzheimer's disease
0.598 0.402 0.000
G82 Paraplegia and tetraplegia
0.598 0.402 0.000
M00-M03 Infectious arthropathies
0.000 0.402 0.598
M07.38 Other psoriatic arthropathies (Other)
0.000 0.403 0.597
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.403 0.597
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.403 0.597
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.403 0.597
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.403 0.597
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.403 0.597
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.403 0.597
K77 Liver disorders in diseases classified elsewhere
0.000 0.406 0.594
K71 Toxic liver disease
0.000 0.406 0.594
J86.9 Pyothorax without fistula
0.000 0.407 0.593
H35.9 Retinal disorder, unspecified
0.000 0.407 0.593
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.408 0.592
H47 Other disorders of optic [2nd] nerve and visual pathways
0.000 0.408 0.592
M70.7 Other bursitis of hip
0.000 0.409 0.591
K74.4 Secondary biliary cirrhosis
0.000 0.409 0.591
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.409 0.591
K74.1 Hepatic sclerosis
0.000 0.409 0.591
I22.8 Subsequent myocardial infarction of other sites
0.000 0.409 0.590
M91-M94 Chondropathies
0.000 0.411 0.589
M70.5 Other bursitis of knee
0.000 0.412 0.588
G40-G47 Episodic and paroxysmal disorders
0.587 0.413 0.000
I45.8 Other specified conduction disorders
0.000 0.414 0.586
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.414 0.586
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.414 0.586
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.414 0.586
E74.2 Disorders of galactose metabolism
0.000 0.414 0.586
E74.1 Disorders of fructose metabolism
0.000 0.414 0.586
E74.0 Glycogen storage disease
0.000 0.414 0.586
K90.8 Other intestinal malabsorption
0.000 0.415 0.584
K75.4 Autoimmune hepatitis
0.000 0.417 0.583
E89.3 Postprocedural hypopituitarism
0.000 0.417 0.582
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.000 0.418 0.582
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.000 0.418 0.582
M70.1 Bursitis of hand
0.000 0.418 0.582
M70.0 Chronic crepitant synovitis of hand and wrist
0.000 0.418 0.582
H35.0 Background retinopathy and retinal vascular changes
0.000 0.418 0.582
M60-M63 Disorders of muscles
0.000 0.418 0.581
I51.5 Myocardial degeneration
0.000 0.418 0.581
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.418 0.581
E88 Other metabolic disorders
0.001 0.420 0.579
G25.9 Extrapyramidal and movement disorder, unspecified
0.579 0.421 0.000
H30.9 Chorioretinal inflammation, unspecified
0.000 0.422 0.578
G11 Hereditary ataxia
0.576 0.423 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.576 0.424 0.000
G83.1 Monoplegia of lower limb
0.576 0.424 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.425 0.575
G80 Infantile cerebral palsy
0.574 0.426 0.000
G25.2 Other specified forms of tremor
0.573 0.427 0.000
I24.1 Dressler's syndrome
0.000 0.427 0.573
I30 Acute pericarditis
0.000 0.427 0.573
M77.0 Medial epicondylitis
0.000 0.427 0.572
I05 Rheumatic mitral valve diseases
0.000 0.429 0.571
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.429 0.571
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.429 0.571
M77.8 Other enthesopathies, not elsewhere classified
0.000 0.431 0.569
M77.3 Calcaneal spur
0.000 0.431 0.569
M77.2 Periarthritis of wrist
0.000 0.431 0.569
Q80-Q89 Other congenital malformations
0.000 0.432 0.568
G81.9 Hemiplegia, unspecified
0.564 0.436 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.000 0.437 0.563
G30.1 Alzheimer's disease with late onset
0.562 0.437 0.000
G24 Dystonia
0.562 0.437 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.562 0.438 0.000
I36 Nonrheumatic tricuspid valve disorders
0.000 0.438 0.562
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.438 0.562
I44 Atrioventricular and left bundle-branch block
0.000 0.439 0.561
K73.9 Chronic hepatitis, unspecified
0.000 0.439 0.561
E11.4 With neurological complications
0.000 0.439 0.561
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.559 0.440 0.000
M71 Other bursopathies
0.000 0.441 0.559
I23.8 Other current complications following acute myocardial infarction
0.000 0.441 0.559
M11.9 Crystal arthropathy, unspecified
0.000 0.441 0.559
M11.8 Other specified crystal arthropathies
0.000 0.441 0.559
M11.1 Familial chondrocalcinosis
0.000 0.441 0.559
M11.0 Hydroxyapatite deposition disease
0.000 0.441 0.559
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.441 0.559
Q60-Q64 Congenital malformations of the urinary system
0.000 0.442 0.558
E73 Lactose intolerance
0.001 0.443 0.556
E89.2 Postprocedural hypoparathyroidism
0.000 0.444 0.556
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.000 0.444 0.556
E06.5 Other chronic thyroiditis
0.000 0.446 0.554
E06.4 Drug-induced thyroiditis
0.000 0.446 0.554
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.446 0.554
E06.1 Subacute thyroiditis
0.000 0.446 0.554
E06.0 Acute thyroiditis
0.000 0.446 0.554
M70.3 Other bursitis of elbow
0.000 0.446 0.553
G82.1 Spastic paraplegia
0.551 0.449 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.551 0.449 0.000
M99 Biomechanical lesions, not elsewhere classified
0.000 0.450 0.549
G83.9 Paralytic syndrome, unspecified
0.547 0.453 0.000
J45.8 Mixed asthma
0.000 0.454 0.546
J45.1 Nonallergic asthma
0.000 0.454 0.546
M70.2 Olecranon bursitis
0.000 0.455 0.545
M70.49 Prepatellar bursitis-Site unspec
0.000 0.455 0.545
M70.48 Prepatellar bursitis-Other
0.000 0.455 0.545
M70.47 Prepatellar bursitis-Ankle/Foot
0.000 0.455 0.545
M70.45 Prepatellar bursitis-Pelvic/Thigh
0.000 0.455 0.545
M70.44 Prepatellar bursitis-Hand
0.000 0.455 0.545
M70.43 Prepatellar bursitis-Forearm
0.000 0.455 0.545
M70.42 Prepatellar bursitis-Upper arm
0.000 0.455 0.545
M70.41 Prepatellar bursitis-Shldr region
0.000 0.455 0.545
M70.40 Prepatellar bursitis-Mult sites
0.000 0.455 0.545

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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