TreeWAS – Variant ID: rs9276826

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.000	1.000
K90 Intestinal malabsorption	0.000	0.000	1.000
Chapter XI Diseases of the digestive system	0.000	0.000	1.000
K90-K93 Other diseases of the digestive system	0.000	0.000	1.000
Chapter II Neoplasms	0.000	0.000	1.000
# Top node	0.000	0.000	1.000
E10 Insulin-dependent diabetes mellitus	0.000	0.000	1.000
E10-E14 Diabetes mellitus	0.000	0.001	0.999
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.001	0.999
E10.9 Without complications	0.000	0.001	0.999
D50-D53 Nutritional anaemias	0.000	0.001	0.999
C15-C26 Malignant neoplasms of digestive organs	0.000	0.002	0.998
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.002	0.998
D50 Iron deficiency anaemia	0.000	0.004	0.996
E20-E35 Disorders of other endocrine glands	0.000	0.005	0.995
D50.8 Other iron deficiency anaemias	0.000	0.009	0.991
K50-K52 Noninfective enteritis and colitis	0.000	0.010	0.990
K50 Crohn's disease [regional enteritis]	0.000	0.013	0.987
I21.9 Acute myocardial infarction, unspecified	0.982	0.018	0.000
E27 Other disorders of adrenal gland	0.000	0.023	0.977
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.029	0.971
D51 Vitamin B12 deficiency anaemia	0.000	0.031	0.969
C64-C68 Malignant neoplasms of urinary tract	0.000	0.032	0.968
K86 Other diseases of pancreas	0.000	0.033	0.967
C67 Malignant neoplasm of bladder	0.000	0.036	0.964
K50.9 Crohn's disease, unspecified	0.000	0.041	0.959
C18 Malignant neoplasm of colon	0.000	0.041	0.959
Chapter XXII Codes for special purposes	0.000	0.042	0.958
K55-K64 Other diseases of intestines	0.000	0.042	0.958
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.043	0.957
C79 Secondary malignant neoplasm of other sites	0.000	0.044	0.956
K56.6 Other and unspecified intestinal obstruction	0.000	0.051	0.949
E22 Hyperfunction of pituitary gland	0.000	0.053	0.947
C21 Malignant neoplasm of anus and anal canal	0.000	0.054	0.946
K50.0 Crohn's disease of small intestine	0.000	0.054	0.946
E10.1 With ketoacidosis	0.000	0.054	0.946
K56 Paralytic ileus and intestinal obstruction without hernia	0.000	0.056	0.944
K86.1 Other chronic pancreatitis	0.000	0.060	0.940
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.062	0.938
D50.9 Iron deficiency anaemia, unspecified	0.000	0.063	0.937
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.067	0.933
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.070	0.930
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.070	0.930
E27.1 Primary adrenocortical insufficiency	0.000	0.076	0.924
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.082	0.918
C67.2 Lateral wall of bladder	0.000	0.084	0.916
I21 Acute myocardial infarction	0.916	0.084	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.085	0.915
C67.9 Bladder, unspecified	0.000	0.085	0.915
K86.8 Other specified diseases of pancreas	0.000	0.090	0.910
C18.7 Sigmoid colon	0.000	0.091	0.909
C77.0 Lymph nodes of head, face and neck	0.000	0.093	0.907
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.000	0.093	0.907
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.097	0.903
E10.3 With ophthalmic complications	0.000	0.103	0.897
C34 Malignant neoplasm of bronchus and lung	0.000	0.105	0.895
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.106	0.894
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.112	0.888
C20 Malignant neoplasm of rectum	0.000	0.116	0.884
K50.8 Other Crohn's disease	0.000	0.120	0.880
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.124	0.876
E00-E07 Disorders of thyroid gland	0.000	0.125	0.875
C34.9 Bronchus or lung, unspecified	0.000	0.128	0.872
D86 Sarcoidosis	0.000	0.134	0.866
K83 Other diseases of biliary tract	0.000	0.134	0.866
K61 Abscess of anal and rectal regions	0.000	0.139	0.861
E03 Other hypothyroidism	0.000	0.139	0.861
K55 Vascular disorders of intestine	0.000	0.140	0.860
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.140	0.860
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.141	0.859
C77.4 Inguinal and lower limb lymph nodes	0.000	0.142	0.858
C18.6 Descending colon	0.000	0.142	0.858
C21.0 Anus, unspecified	0.000	0.144	0.856
E03.9 Hypothyroidism, unspecified	0.000	0.145	0.855
I21.2 Acute transmural myocardial infarction of other sites	0.854	0.146	0.000
C78.0 Secondary malignant neoplasm of lung	0.000	0.147	0.853
U89 Agent resistant to other and unspecified antibiotics	0.000	0.150	0.850
K62 Other diseases of anus and rectum	0.000	0.151	0.849
C79.6 Secondary malignant neoplasm of ovary	0.000	0.152	0.848
C51-C58 Malignant neoplasms of female genital organs	0.000	0.154	0.846
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.000	0.157	0.843
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.159	0.841
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.160	0.840
K65-K67 Diseases of peritoneum	0.000	0.160	0.840
I25.8 Other forms of chronic ischaemic heart disease	0.839	0.161	0.000
I20-I25 Ischaemic heart diseases	0.837	0.163	0.000
C21.1 Anal canal	0.000	0.164	0.836
I25 Chronic ischaemic heart disease	0.834	0.166	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.166	0.834
K90.9 Intestinal malabsorption, unspecified	0.000	0.171	0.829
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.173	0.827
E21.0 Primary hyperparathyroidism	0.000	0.174	0.826
E50-E64 Other nutritional deficiencies	0.000	0.177	0.823
C22.0 Liver cell carcinoma	0.000	0.177	0.823
K62.0 Anal polyp	0.000	0.177	0.823
K83.1 Obstruction of bile duct	0.000	0.177	0.823
C77.8 Lymph nodes of multiple regions	0.000	0.179	0.821
C67.6 Ureteric orifice	0.000	0.182	0.818
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.187	0.813
E22.0 Acromegaly and pituitary gigantism	0.000	0.189	0.811
C22.1 Intrahepatic bile duct carcinoma	0.000	0.189	0.811
U89.8 Agent resistant to other single specified antibiotic	0.000	0.191	0.809
E14 Unspecified diabetes mellitus	0.000	0.196	0.804
C80 Malignant neoplasm without specification of site	0.000	0.196	0.804
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.196	0.804
K55.2 Angiodysplasia of colon	0.000	0.204	0.796
E22.1 Hyperprolactinaemia	0.000	0.205	0.794
E27.8 Other specified disorders of adrenal gland	0.000	0.208	0.792
K61.0 Anal abscess	0.000	0.209	0.791
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.209	0.791
K52 Other non-infective gastro-enteritis and colitis	0.000	0.211	0.789
C18.2 Ascending colon	0.000	0.214	0.786
E53 Deficiency of other B group vitamins	0.000	0.215	0.785
D68 Other coagulation defects	0.000	0.215	0.785
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.222	0.778
C77.9 Lymph node, unspecified	0.000	0.224	0.776
E20 Hypoparathyroidism	0.000	0.229	0.770
C34.1 Upper lobe, bronchus or lung	0.000	0.232	0.768
C79.2 Secondary malignant neoplasm of skin	0.000	0.235	0.765
E40-E46 Malnutrition	0.000	0.238	0.762
C18.5 Splenic flexure	0.000	0.239	0.761
E10.8 With unspecified complications	0.000	0.242	0.758
E16 Other disorders of pancreatic internal secretion	0.000	0.242	0.758
E53.8 Deficiency of other specified B group vitamins	0.000	0.242	0.758
D86.9 Sarcoidosis, unspecified	0.000	0.247	0.753
K65 Peritonitis	0.000	0.249	0.751
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.250	0.750
E27.2 Addisonian crisis	0.000	0.255	0.745
C60-C63 Malignant neoplasms of male genital organs	0.000	0.257	0.743
C18.3 Hepatic flexure	0.000	0.257	0.742
D86.8 Sarcoidosis of other and combined sites	0.000	0.259	0.741
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.260	0.740
U88 Agent resistant to multiple antibiotics	0.000	0.261	0.739
C67.0 Trigone of bladder	0.000	0.261	0.739
C78.2 Secondary malignant neoplasm of pleura	0.000	0.261	0.739
E27.9 Disorder of adrenal gland, unspecified	0.000	0.268	0.732
U80 Agent resistant to penicillin and related antibiotics	0.000	0.269	0.731
C67.8 Overlapping lesion of bladder	0.000	0.269	0.731
C07 Malignant neoplasm of parotid gland	0.000	0.270	0.730
E10.6 With other specified complications	0.000	0.271	0.729
D52 Folate deficiency anaemia	0.000	0.276	0.724
K62.3 Rectal prolapse	0.000	0.276	0.724
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.276	0.724
C56 Malignant neoplasm of ovary	0.000	0.277	0.723
D86.0 Sarcoidosis of lung	0.000	0.277	0.723
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.280	0.719
K62.9 Disease of anus and rectum, unspecified	0.000	0.282	0.718
K90.3 Pancreatic steatorrhoea	0.000	0.283	0.717
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.283	0.717
K90.1 Tropical sprue	0.000	0.283	0.717
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.283	0.717
C40-C41 Malignant neoplasms of bone and articular cartilage	0.000	0.283	0.717
Chapter XVI Certain conditions originating in the perinatal period	0.000	0.283	0.717
E10.7 With multiple complications	0.000	0.283	0.717
E10.0 With coma	0.000	0.283	0.717
E12 Malnutrition-related diabetes mellitus	0.000	0.283	0.716
K83.0 Cholangitis	0.000	0.285	0.715
D50.1 Sideropenic dysphagia	0.000	0.286	0.714
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.286	0.714
E32 Diseases of thymus	0.000	0.286	0.714
E31 Polyglandular dysfunction	0.000	0.286	0.714
E30 Disorders of puberty, not elsewhere classified	0.000	0.286	0.714
E25 Adrenogenital disorders	0.000	0.286	0.714
E24 Cushing's syndrome	0.000	0.287	0.713
K55.9 Vascular disorder of intestine, unspecified	0.000	0.287	0.713
K62.6 Ulcer of anus and rectum	0.000	0.288	0.712
C67.3 Anterior wall of bladder	0.000	0.289	0.711
E14.9 Without complications	0.000	0.290	0.710
C44 Other malignant neoplasms of skin	0.709	0.291	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.291	0.709
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.293	0.707
C18.1 Appendix	0.000	0.293	0.707
C09 Malignant neoplasm of tonsil	0.000	0.293	0.707
C44.2 Skin of ear and external auricular canal	0.707	0.293	0.000
C67.4 Posterior wall of bladder	0.000	0.294	0.706
K86.3 Pseudocyst of pancreas	0.000	0.295	0.705
D66 Hereditary factor VIII deficiency	0.000	0.297	0.703
E16.2 Hypoglycaemia, unspecified	0.000	0.297	0.703
C23 Malignant neoplasm of gallbladder	0.000	0.298	0.702
E27.5 Adrenomedullary hyperfunction	0.000	0.299	0.700
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.299	0.700
E27.0 Other adrenocortical overactivity	0.000	0.299	0.700
E10.2 With renal complications	0.000	0.301	0.699
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.302	0.698
C18.0 Caecum	0.000	0.302	0.698
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.304	0.696
C66 Malignant neoplasm of ureter	0.000	0.305	0.695
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.305	0.695
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.305	0.695
D51.2 Transcobalamin II deficiency	0.000	0.305	0.695
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.305	0.695
C68 Malignant neoplasm of other and unspecified urinary organs	0.000	0.306	0.694
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.307	0.693
K65.9 Peritonitis, unspecified	0.000	0.308	0.692
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.308	0.692
K90.8 Other intestinal malabsorption	0.000	0.309	0.691
C67.7 Urachus	0.000	0.309	0.691
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.309	0.691
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.309	0.691
K85 Acute pancreatitis	0.000	0.310	0.689
C22.9 Liver, unspecified	0.000	0.311	0.689
K64 Haemorrhoids and perianal venous thrombosis	0.000	0.313	0.687
D68.0 Von Willebrand's disease	0.000	0.316	0.684
C01 Malignant neoplasm of base of tongue	0.000	0.318	0.682
D55-D59 Haemolytic anaemias	0.000	0.318	0.681
M81.9 Osteoporosis, unspecified	0.000	0.320	0.680
C17 Malignant neoplasm of small intestine	0.000	0.320	0.679
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.321	0.679
E22.8 Other hyperfunction of pituitary gland	0.000	0.321	0.679
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.321	0.678
C21.2 Cloacogenic zone	0.000	0.321	0.678
C51 Malignant neoplasm of vulva	0.000	0.321	0.679
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.323	0.677
C55 Malignant neoplasm of uterus, part unspecified	0.000	0.326	0.674
C77.2 Intra-abdominal lymph nodes	0.000	0.326	0.674
I25.3 Aneurysm of heart	0.673	0.326	0.000
I25.2 Old myocardial infarction	0.669	0.331	0.000
C22.7 Other specified carcinomas of liver	0.000	0.331	0.669
C22.4 Other sarcomas of liver	0.000	0.331	0.669
C22.3 Angiosarcoma of liver	0.000	0.331	0.669
C22.2 Hepatoblastoma	0.000	0.331	0.669
I21.0 Acute transmural myocardial infarction of anterior wall	0.668	0.332	0.000
C53 Malignant neoplasm of cervix uteri	0.000	0.332	0.668
E10.4 With neurological complications	0.000	0.332	0.668
U80.1 Methicillin resistant agent	0.000	0.332	0.668
C67.1 Dome of bladder	0.000	0.332	0.668
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.333	0.667
C31 Malignant neoplasm of accessory sinuses	0.000	0.333	0.667
C37 Malignant neoplasm of thymus	0.000	0.333	0.667
C33 Malignant neoplasm of trachea	0.000	0.333	0.667
C44.3 Skin of other and unspecified parts of face	0.663	0.337	0.000
K56.2 Volvulus	0.000	0.337	0.663
D53 Other nutritional anaemias	0.000	0.340	0.660
I21.X Presumed acute myicardial infaction (unconfirmed)	0.657	0.343	0.000
D83 Common variable immunodeficiency	0.000	0.344	0.656
D82 Immunodeficiency associated with other major defects	0.000	0.344	0.656
D81 Combined immunodeficiencies	0.000	0.344	0.656
C67.5 Bladder neck	0.000	0.346	0.654
C10 Malignant neoplasm of oropharynx	0.000	0.348	0.652
K56.3 Gallstone ileus	0.000	0.350	0.650
U84 Resistance to other antimicrobial drugs	0.000	0.350	0.650
U83 Resistance to other antibiotics	0.000	0.350	0.650
U82 Resistance to betalactam antibiotics	0.000	0.350	0.650
U85 Resistance to antineoplastic drugs	0.000	0.350	0.650
E26 Hyperaldosteronism	0.000	0.353	0.647
E13 Other specified diabetes mellitus	0.000	0.353	0.647
K91.4 Colostomy and enterostomy malfunction	0.000	0.353	0.647
E28 Ovarian dysfunction	0.000	0.353	0.647
C32 Malignant neoplasm of larynx	0.000	0.354	0.646
C44.0 Skin of lip	0.646	0.354	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.355	0.645
K61.1 Rectal abscess	0.000	0.358	0.642
C34.8 Overlapping lesion of bronchus and lung	0.000	0.358	0.642
M81 Osteoporosis without pathological fracture	0.001	0.358	0.641
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.000	0.359	0.640
D68.8 Other specified coagulation defects	0.000	0.360	0.640
K91.1 Postgastric surgery syndromes	0.000	0.361	0.639
C44.5 Skin of trunk	0.638	0.362	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.638	0.362	0.000
E29 Testicular dysfunction	0.000	0.362	0.637
E21.3 Hyperparathyroidism, unspecified	0.000	0.362	0.637
D37-D48 Neoplasms of uncertain or unknown behaviour	0.000	0.363	0.637
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.363	0.637
E21.4 Other specified disorders of parathyroid gland	0.000	0.363	0.637
E21.2 Other hyperparathyroidism	0.000	0.363	0.637
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.366	0.633
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.367	0.633
E34 Other endocrine disorders	0.000	0.369	0.631
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.369	0.631
C34.0 Main bronchus	0.000	0.371	0.629
K91.5 Postcholecystectomy syndrome	0.000	0.372	0.628
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.372	0.628
C18.8 Overlapping lesion of colon	0.000	0.372	0.628
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.373	0.627
E00 Congenital iodine-deficiency syndrome	0.000	0.373	0.627
E14.3 With ophthalmic complications	0.000	0.375	0.625
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.002	0.376	0.622
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.378	0.622
D86.3 Sarcoidosis of skin	0.000	0.379	0.621
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.379	0.621
C44.7 Skin of lower limb, including hip	0.621	0.379	0.000
K83.5 Biliary cyst	0.000	0.379	0.621
K83.4 Spasm of sphincter of Oddi	0.000	0.379	0.621
K83.3 Fistula of bile duct	0.000	0.379	0.621
K83.2 Perforation of bile duct	0.000	0.379	0.621
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.000	0.379	0.620
C16 Malignant neoplasm of stomach	0.000	0.380	0.620
M80-M85 Disorders of bone density and structure	0.002	0.380	0.618
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.381	0.619
K61.4 Intrasphincteric abscess	0.000	0.382	0.618
K61.2 Anorectal abscess	0.000	0.382	0.618
D86.1 Sarcoidosis of lymph nodes	0.000	0.383	0.617
E03.5 Myxoedema coma	0.000	0.383	0.617
E03.4 Atrophy of thyroid (acquired)	0.000	0.383	0.617
E03.3 Postinfectious hypothyroidism	0.000	0.383	0.617
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.383	0.617
E03.1 Congenital hypothyroidism without goitre	0.000	0.383	0.617
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.383	0.617
K55.8 Other vascular disorders of intestine	0.000	0.383	0.617
D67 Hereditary factor IX deficiency	0.000	0.383	0.617
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.383	0.617
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.384	0.616
E15 Nondiabetic hypoglycaemic coma	0.000	0.384	0.616
I23 Certain current complications following acute myocardial infarction	0.615	0.385	0.000
K91.3 Postoperative intestinal obstruction	0.000	0.387	0.613
D80 Immunodeficiency with predominantly antibody defects	0.000	0.387	0.612
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.390	0.610
C15 Malignant neoplasm of oesophagus	0.000	0.390	0.610
U89.9 Agent resistant to unspecified antibiotic	0.000	0.390	0.609
E20.9 Hypoparathyroidism, unspecified	0.000	0.391	0.609
C09.9 Tonsil, unspecified	0.000	0.391	0.609
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.391	0.609
I24 Other acute ischaemic heart diseases	0.609	0.391	0.000
K85.9 Acute pancreatitis, unspecified	0.000	0.392	0.608
D68.6 Other Thrombophilia	0.000	0.392	0.608
C58 Malignant neoplasm of placenta	0.000	0.393	0.607
K62.2 Anal prolapse	0.000	0.393	0.607
M81.98 Osteoporosis, unspecified (Other)	0.000	0.394	0.606
M50-M54 Other dorsopathies	0.000	0.394	0.606
K65.8 Other peritonitis	0.000	0.395	0.605
C13 Malignant neoplasm of hypopharynx	0.000	0.395	0.605
C08 Malignant neoplasm of other and unspecified major salivary glands	0.000	0.395	0.605
C04 Malignant neoplasm of floor of mouth	0.000	0.395	0.605
C00 Malignant neoplasm of lip	0.000	0.395	0.605
E23 Hypofunction and other disorders of pituitary gland	0.000	0.397	0.603
K62.7 Radiation proctitis	0.000	0.397	0.603
I25.5 Ischaemic cardiomyopathy	0.603	0.397	0.000
K50.1 Crohn's disease of large intestine	0.000	0.398	0.602
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.398	0.602
K52.3 Indeterminate colitis	0.000	0.398	0.602
C12 Malignant neoplasm of pyriform sinus	0.000	0.400	0.600
I25.6 Silent myocardial ischaemia	0.598	0.402	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.596	0.404	0.000
K55.0 Acute vascular disorders of intestine	0.000	0.404	0.596
K61.3 Ischiorectal abscess	0.000	0.405	0.595
M50 Cervical disk disorders	0.000	0.408	0.592
E46 Unspecified protein-energy malnutrition	0.000	0.408	0.592
I25.1 Atherosclerotic heart disease	0.591	0.409	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.409	0.591
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.409	0.590
E63 Other nutritional deficiencies	0.000	0.409	0.590
E56 Other vitamin deficiencies	0.000	0.409	0.590
E51 Thiamine deficiency	0.000	0.409	0.590
E50 Vitamin A deficiency	0.000	0.409	0.590
E60 Dietary zinc deficiency	0.000	0.409	0.590
E59 Dietary selenium deficiency	0.000	0.409	0.590
E54 Ascorbic acid deficiency	0.000	0.409	0.590
E52 Niacin deficiency [pellagra]	0.000	0.409	0.590
C05 Malignant neoplasm of palate	0.000	0.410	0.590
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.414	0.586
D84 Other immunodeficiencies	0.000	0.418	0.582
C62 Malignant neoplasm of testis	0.000	0.419	0.581
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.419	0.581
C43-C44 Melanoma and other malignant neoplasms of skin	0.379	0.419	0.202
E14.8 With unspecified complications	0.000	0.423	0.577
E14.7 With multiple complications	0.000	0.423	0.577
E14.6 With other specified complications	0.000	0.423	0.577
E14.5 With peripheral circulatory complications	0.000	0.423	0.577
E14.2 Withrenal complications	0.000	0.423	0.577
E14.0 With coma	0.000	0.423	0.577
U50 Level of care administered to neonates	0.000	0.424	0.576
U07 Emergency use of U07	0.000	0.424	0.576
U06 Emergency use of U06	0.000	0.424	0.576
U04 Severe acute respiratory syndrome [SARS]	0.000	0.424	0.576
U52 First in a series of a regular day/night admissions	0.000	0.424	0.576
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.426	0.574
C52 Malignant neoplasm of vagina	0.000	0.428	0.572
E06 Thyroiditis	0.000	0.428	0.572
C78.1 Secondary malignant neoplasm of mediastinum	0.000	0.430	0.569
E07 Other disorders of thyroid	0.000	0.435	0.565
D59 Acquired haemolytic anaemia	0.000	0.436	0.564
K56.0 Paralytic ileus	0.000	0.436	0.564
C11 Malignant neoplasm of nasopharynx	0.000	0.436	0.564
E53.1 Pyridoxine deficiency	0.000	0.437	0.563
E53.0 Riboflavin deficiency	0.000	0.437	0.563
D68.4 Acquired coagulation factor deficiency	0.000	0.437	0.563
D68.1 Hereditary factor XI deficiency	0.000	0.437	0.563
C06 Malignant neoplasm of other and unspecified parts of mouth	0.000	0.438	0.562
C03 Malignant neoplasm of gum	0.000	0.438	0.562
E53.9 Vitamin B deficiency, unspecified	0.000	0.438	0.562
K60 Fissure and fistula of anal and rectal regions	0.000	0.441	0.559
C51.9 Vulva, unspecified	0.000	0.442	0.558
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.000	0.442	0.558
D41.4 Bladder	0.000	0.443	0.557
D68.5 Primary Thrombophilia	0.000	0.444	0.556
M50.1 Cervical disk disorder with radiculopathy	0.000	0.445	0.555
C77.5 Intrapelvic lymph nodes	0.000	0.447	0.553
C34.2 Middle lobe, bronchus or lung	0.000	0.447	0.553
E20.8 Other hypoparathyroidism	0.000	0.447	0.552
E20.1 Pseudohypoparathyroidism	0.000	0.447	0.552
E20.0 Idiopathic hypoparathyroidism	0.000	0.447	0.552
K83.9 Disease of biliary tract, unspecified	0.000	0.448	0.552
K62.4 Stenosis of anus and rectum	0.000	0.450	0.550
C44.6 Skin of upper limb, including shoulder	0.549	0.451	0.000
M53 Other dorsopathies, not elsewhere classified	0.000	0.451	0.549
U81 Agent resistant to vancomycin and related antibiotics	0.000	0.451	0.549
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.452	0.548
C78.7 Secondary malignant neoplasm of liver	0.000	0.452	0.548
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.452	0.548
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.453	0.547
E45 Retarded development following protein-energy malnutrition	0.000	0.453	0.547
E43 Unspecified severe protein-energy malnutrition	0.000	0.453	0.547
E42 Marasmic kwashiorkor	0.000	0.453	0.547
E41 Nutritional marasmus	0.000	0.453	0.547
E40 Kwashiorkor	0.000	0.453	0.547
K86.9 Disease of pancreas, unspecified	0.000	0.454	0.546
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.457	0.543
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.457	0.543
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.457	0.543
E16.4 Abnormal secretion of gastrin	0.000	0.457	0.543
E16.3 Increased secretion of glucagon	0.000	0.457	0.543
I24.9 Acute ischaemic heart disease, unspecified	0.542	0.458	0.000
C44.1 Skin of eyelid, including canthus	0.541	0.459	0.000
C53.9 Cervix uteri, unspecified	0.000	0.459	0.541
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.460	0.540
M50.0 Cervical disk disorder with myelopathy	0.000	0.461	0.539
M45-M49 Spondylopathies	0.001	0.462	0.537
K86.2 Cyst of pancreas	0.000	0.466	0.534
I25.4 Coronary artery aneurysm	0.534	0.466	0.000
K56.4 Other impaction of intestine	0.000	0.467	0.533
C63 Malignant neoplasm of other and unspecified male genital organs	0.000	0.467	0.533
C60 Malignant neoplasm of penis	0.000	0.467	0.533
C57 Malignant neoplasm of other and unspecified female genital organs	0.000	0.467	0.532
M50.2 Other cervical disk displacement	0.000	0.468	0.532
E16.1 Other hypoglycaemia	0.000	0.468	0.532
C32.1 Supraglottis	0.000	0.468	0.532
K66 Other disorders of peritoneum	0.000	0.468	0.532
M48 Other spondylopathies	0.000	0.471	0.529
D52.9 Folate deficiency anaemia, unspecified	0.000	0.473	0.527
C80.9 Malignant neoplasm, unspecified	0.000	0.474	0.526
K63 Other diseases of intestine	0.000	0.475	0.525
D73 Diseases of spleen	0.000	0.477	0.523
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.000	0.478	0.521
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.479	0.521
C26.0 Intestinal tract, part unspecified	0.000	0.480	0.520
D52.8 Other folate deficiency anaemias	0.000	0.481	0.519
D52.1 Drug-induced folate deficiency anaemia	0.000	0.481	0.519
D52.0 Dietary folate deficiency anaemia	0.000	0.481	0.519
M48.0 Spinal stenosis	0.000	0.481	0.519
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.482	0.518
E61 Deficiency of other nutrient elements	0.000	0.482	0.518
C44.4 Skin of scalp and neck	0.518	0.482	0.000
K81 Cholecystitis	0.000	0.482	0.518
E03.8 Other specified hypothyroidism	0.000	0.482	0.517
C17.0 Duodenum	0.000	0.483	0.517
C26.9 Ill-defined sites within the digestive system	0.000	0.484	0.516
C26.8 Overlapping lesion of digestive system	0.000	0.484	0.516
C26.1 Spleen	0.000	0.484	0.516
D72 Other disorders of white blood cells	0.000	0.485	0.515
C10.9 Oropharynx, unspecified	0.000	0.485	0.514
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.486	0.514
K93.1 Megacolon in Chagas' disease	0.000	0.486	0.514
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.486	0.514
C42 hematopoietic and reticuloendothelial systems (ICD-O-3 specific)	0.000	0.486	0.514
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.000	0.486	0.514
C40 Malignant neoplasm of bone and articular cartilage of limbs	0.000	0.486	0.514
P90-P96 Other disorders originating in the perinatal period	0.000	0.486	0.514
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.000	0.486	0.514
P75-P78 Digestive system disorders of fetus and newborn	0.000	0.486	0.514
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.000	0.486	0.514
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.000	0.486	0.514
P35-P39 Infections specific to the perinatal period	0.000	0.486	0.514
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.000	0.486	0.514
P10-P15 Birth trauma	0.000	0.486	0.514
P05-P08 Disorders related to length of gestation and fetal growth	0.000	0.486	0.514
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.000	0.486	0.514
E12.9 Without complications	0.000	0.486	0.514
E12.8 With unspecified complications	0.000	0.486	0.514
E12.7 With multiple complications	0.000	0.486	0.514
E12.6 With other specified complications	0.000	0.486	0.514
E12.5 With peripheral circulatory complications	0.000	0.486	0.514
E12.4 With neurological complications	0.000	0.486	0.514
E12.3 With ophthalmic complications	0.000	0.486	0.514
E12.2 With renal complications	0.000	0.486	0.514
E12.1 With ketoacidosis	0.000	0.486	0.514
E12.0 With coma	0.000	0.486	0.514
E25.9 Adrenogenital disorder, unspecified	0.000	0.488	0.512
E25.8 Other adrenogenital disorders	0.000	0.488	0.512
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.488	0.512
E30.9 Disorder of puberty, unspecified	0.000	0.488	0.512
E30.8 Other disorders of puberty	0.000	0.488	0.512
E30.1 Precocious puberty	0.000	0.488	0.512
E30.0 Delayed puberty	0.000	0.488	0.512
E31.9 Polyglandular dysfunction, unspecified	0.000	0.488	0.512
E31.8 Other polyglandular dysfunction	0.000	0.488	0.512
E31.1 Polyglandular hyperfunction	0.000	0.488	0.512
E31.0 Autoimmune polyglandular failure	0.000	0.488	0.512
E32.9 Disease of thymus, unspecified	0.000	0.488	0.512
E32.8 Other diseases of thymus	0.000	0.488	0.512
E32.1 Abscess of thymus	0.000	0.488	0.512
E32.0 Persistent hyperplasia of thymus	0.000	0.488	0.512
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.488	0.512
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.488	0.512
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.488	0.512
E24.8 Other Cushing's syndrome	0.000	0.488	0.511
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.488	0.511
E24.3 Ectopic ACTH syndrome	0.000	0.488	0.511
E24.2 Drug-induced Cushing's syndrome	0.000	0.488	0.511
E24.1 Nelson's syndrome	0.000	0.488	0.511

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations