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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9444453
log Bayes Factor = 11.4696
Chromosome 6   position 87,599,030  (GRCh37) Explore rs9444453 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
S00-S09 Injuries to the head
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
I51 Complications and ill-defined descriptions of heart disease
0.998 0.002 0.000
W00-W19 Falls
0.997 0.003 0.000
Chapter XX External causes of morbidity and mortality
0.997 0.003 0.000
W19 Unspecified fall
0.996 0.004 0.000
I60-I69 Cerebrovascular diseases
0.995 0.005 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.993 0.007 0.000
W19.9 Unspecified place
0.992 0.008 0.000
I63 Cerebral infarction
0.991 0.009 0.000
F41 Other anxiety disorders
0.988 0.012 0.000
I51.7 Cardiomegaly
0.984 0.016 0.000
S01 Open wound of head
0.981 0.019 0.000
F41.2 Mixed anxiety and depressive disorder
0.981 0.019 0.000
I63.9 Cerebral infarction, unspecified
0.979 0.021 0.000
I47 Paroxysmal tachycardia
0.974 0.026 0.000
I45 Other conduction disorders
0.970 0.030 0.000
I49 Other cardiac arrhythmias
0.968 0.032 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.967 0.033 0.000
M20-M25 Other joint disorders
0.965 0.035 0.000
I51.8 Other ill-defined heart diseases
0.965 0.035 0.000
I45.1 Other and unspecified right bundle-branch block
0.960 0.040 0.000
Chapter VI Diseases of the nervous system
0.956 0.044 0.000
M23 Internal derangement of knee
0.952 0.048 0.000
S00 Superficial injury of head
0.950 0.050 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.945 0.055 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.945 0.055 0.000
M23.3 Other meniscus derangements
0.943 0.057 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.942 0.058 0.000
I44 Atrioventricular and left bundle-branch block
0.942 0.058 0.000
L60-L75 Disorders of skin appendages
0.936 0.064 0.000
M25 Other joint disorders, not elsewhere classified
0.936 0.064 0.000
S60-S69 Injuries to the wrist and hand
0.928 0.072 0.000
W19.2 School, other institution and public administrative area
0.920 0.080 0.000
I44.7 Left bundle-branch block, unspecified
0.918 0.082 0.000
I47.1 Supraventricular tachycardia
0.914 0.086 0.000
I69 Sequelae of cerebrovascular disease
0.914 0.086 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.914 0.086 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.892 0.108 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.888 0.112 0.000
S80-S89 Injuries to the knee and lower leg
0.884 0.116 0.000
G40-G47 Episodic and paroxysmal disorders
0.884 0.116 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.883 0.117 0.000
M25.7 Osteophyte
0.883 0.117 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.882 0.117 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.882 0.118 0.000
L60 Nail disorders
0.880 0.120 0.000
I49.0 Ventricular fibrillation and flutter
0.879 0.121 0.000
S06 Intracranial injury
0.867 0.133 0.000
S90-S99 Injuries to the ankle and foot
0.867 0.133 0.000
Chapter XXII Codes for special purposes
0.866 0.134 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.865 0.135 0.000
I47.2 Ventricular tachycardia
0.865 0.135 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.864 0.136 0.000
S01.3 Open wound of ear
0.859 0.141 0.000
G40 Epilepsy
0.857 0.143 0.000
S01.9 Open wound of head, part unspecified
0.854 0.146 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.852 0.148 0.000
G90-G99 Other disorders of the nervous system
0.849 0.151 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.848 0.152 0.000
I51.0 Cardiac septal defect, acquired
0.848 0.152 0.000
L60.0 Ingrowing nail
0.847 0.153 0.000
M40-M43 Deforming dorsopathies
0.846 0.154 0.000
I49.9 Cardiac arrhythmia, unspecified
0.846 0.154 0.000
I49.3 Ventricular premature depolarisation
0.845 0.155 0.000
F03 Unspecified dementia
0.844 0.156 0.000
S62 Fracture at wrist and hand level
0.842 0.158 0.000
S01.0 Open wound of scalp
0.842 0.158 0.000
W06 Fall involving bed
0.840 0.160 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.840 0.160 0.000
S00.8 Superficial injury of other parts of head
0.837 0.163 0.000
I60 Subarachnoid haemorrhage
0.837 0.163 0.000
M21 Other acquired deformities of limbs
0.835 0.165 0.000
Chapter I Certain infectious and parasitic diseases
0.830 0.170 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.827 0.173 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.823 0.177 0.000
Chapter VIII Diseases of the ear and mastoid process
0.821 0.179 0.000
O85-O92 Complications predominantly related to the puerperium
0.820 0.180 0.000
L72.0 Epidermal cyst
0.818 0.182 0.000
F43 Reaction to severe stress, and adjustment disorders
0.817 0.183 0.000
M33 Dermatopolymyositis
0.816 0.184 0.000
S01.5 Open wound of lip and oral cavity
0.815 0.185 0.000
I42 Cardiomyopathy
0.814 0.186 0.000
S50-S59 Injuries to the elbow and forearm
0.813 0.187 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.810 0.190 0.000
I49.4 Other and unspecified premature depolarisation
0.810 0.190 0.000
S00.9 Superficial injury of head, part unspecified
0.810 0.190 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.809 0.191 0.000
S01.8 Open wound of other parts of head
0.808 0.192 0.000
W15 Fall from cliff
0.806 0.194 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.806 0.194 0.000
M23.5 Chronic instability of knee
0.804 0.196 0.000
S05 Injury of eye and orbit
0.803 0.197 0.000
W07 Fall involving chair
0.803 0.197 0.000
G20-G26 Extrapyramidal and movement disorders
0.803 0.197 0.000
W19.4 Street and highway
0.802 0.198 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.801 0.199 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.801 0.199 0.000
M91-M94 Chondropathies
0.800 0.200 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.798 0.202 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.797 0.203 0.000
O40 Polyhydramnios
0.796 0.204 0.000
I44.2 Atrioventricular block, complete
0.795 0.205 0.000
S00.7 Multiple superficial injuries of head
0.792 0.208 0.000
B35-B49 Mycoses
0.792 0.208 0.000
S32 Fracture of lumbar spine and pelvis
0.785 0.215 0.000
S02 Fracture of skull and facial bones
0.785 0.215 0.000
M25.8 Other specified joint disorders
0.784 0.216 0.000
T91 Sequelae of injuries of neck and trunk
0.778 0.222 0.000
S92 Fracture of foot, except ankle
0.778 0.222 0.000
S64 Injury of nerves at wrist and hand level
0.777 0.223 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.777 0.223 0.000
M23.9 Internal derangement of knee, unspecified
0.776 0.224 0.000
V80-V89 Other land transport accidents
0.775 0.225 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.774 0.226 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.774 0.226 0.000
S81 Open wound of lower leg
0.774 0.226 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.773 0.227 0.000
T00-T07 Injuries involving multiple body regions
0.773 0.227 0.000
S10-S19 Injuries to the neck
0.773 0.227 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.773 0.227 0.000
L71 Rosacea
0.772 0.228 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.770 0.230 0.000
Q28 Other congenital malformations of circulatory system
0.766 0.234 0.000
G91 Hydrocephalus
0.764 0.236 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.763 0.237 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.763 0.237 0.000
S09 Other and unspecified injuries of head
0.763 0.237 0.000
T79-T79 Certain early complications of trauma
0.762 0.238 0.000
I63.8 Other cerebral infarction
0.761 0.239 0.000
S70-S79 Injuries to the hip and thigh
0.761 0.239 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.759 0.241 0.000
S01.2 Open wound of nose
0.759 0.241 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.758 0.242 0.000
I69.3 Sequelae of cerebral infarction
0.757 0.243 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.757 0.243 0.000
I61 Intracerebral haemorrhage
0.756 0.244 0.000
X10-X19 Contact with heat and hot substances
0.755 0.245 0.000
M25.74 Osteophyte (Hand)
0.754 0.246 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.754 0.246 0.000
F99-F99 Unspecified mental disorder
0.753 0.247 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.753 0.247 0.000
B37 Candidiasis
0.753 0.247 0.000
W19.3 Sports and athletics area
0.752 0.248 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.751 0.249 0.000
F40 Phobic anxiety disorders
0.750 0.250 0.000
O80-O84 Delivery
0.750 0.250 0.000
L82 Seborrhoeic keratosis
0.750 0.250 0.000
L73 Other follicular disorders
0.749 0.251 0.000
W13 Fall from, out of or through building or structure
0.748 0.251 0.000
S62.6 Fracture of other finger
0.748 0.252 0.000
M34 Systemic sclerosis
0.746 0.254 0.000
M23.4 Loose body in knee
0.743 0.257 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.743 0.257 0.000
W20-W49 Exposure to inanimate mechanical forces
0.743 0.257 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.743 0.257 0.000
S80 Superficial injury of lower leg
0.742 0.258 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.740 0.260 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.739 0.261 0.000
M25.3 Other instability of joint
0.737 0.263 0.000
F30-F39 Mood [affective] disorders
0.737 0.263 0.000
G43 Migraine
0.736 0.264 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.736 0.264 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.735 0.265 0.000
M31 Other necrotising vasculopathies
0.734 0.266 0.000
F41.1 Generalised anxiety disorder
0.732 0.267 0.000
G40.9 Epilepsy, unspecified
0.732 0.268 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.732 0.268 0.000
S00.3 Superficial injury of nose
0.731 0.269 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.730 0.270 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.729 0.271 0.000
O48 Prolonged pregnancy
0.729 0.271 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.729 0.271 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.728 0.272 0.000
W06.0 Home
0.728 0.272 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.727 0.273 0.000
M45-M49 Spondylopathies
0.727 0.273 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.726 0.273 0.000
O36 Maternal care for other known or suspected foetal problems
0.726 0.274 0.000
L89 Decubitus ulcer
0.725 0.275 0.000
M41 Scoliosis
0.725 0.275 0.000
Q60-Q64 Congenital malformations of the urinary system
0.723 0.277 0.000
I45.2 Bifascicular block
0.723 0.277 0.000
M25.5 Pain in joint
0.721 0.279 0.000
L91 Hypertrophic disorders of skin
0.720 0.280 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.719 0.281 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.719 0.281 0.000
I46 Cardiac arrest
0.717 0.282 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
S08 Traumatic amputation of part of head
0.716 0.283 0.000
S07 Crushing injury of head
0.716 0.283 0.000
S04 Injury of cranial nerves
0.716 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
I51.6 Cardiovascular disease, unspecified
0.716 0.284 0.000
I51.5 Myocardial degeneration
0.716 0.284 0.000
I51.4 Myocarditis, unspecified
0.716 0.284 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.716 0.284 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.716 0.284 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.716 0.284 0.000
W18 Other fall on same level
0.715 0.285 0.000
W17 Other fall from one level to another
0.715 0.285 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.715 0.285 0.000
W14 Fall from tree
0.715 0.285 0.000
W12 Fall on and from scaffolding
0.715 0.285 0.000
W11 Fall on and from ladder
0.715 0.285 0.000
W09 Fall involving playground equipment
0.715 0.285 0.000
W08 Fall involving other furniture
0.715 0.285 0.000
W05 Fall involving wheelchair
0.715 0.285 0.000
W04 Fall while being carried or supported by other persons
0.715 0.285 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.715 0.285 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.715 0.285 0.000
W00 Fall on same level involving ice and snow
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.715 0.285 0.000
W19.8 Other specified place
0.714 0.286 0.000
W19.5 Trade and service area
0.714 0.286 0.000
W19.0 Home
0.714 0.286 0.000
W19.7 Farm
0.714 0.286 0.000
W19.6 Industrial and construction area
0.714 0.286 0.000
W19.1 Residential institution
0.714 0.286 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.713 0.287 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.713 0.287 0.000
F48 Other neurotic disorders
0.712 0.288 0.000
F44 Dissociative [conversion] disorders
0.712 0.288 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.711 0.289 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.711 0.289 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.711 0.289 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.711 0.289 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.711 0.289 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.711 0.289 0.000
M25.71 Osteophyte (Shoulder region)
0.710 0.290 0.000
M24 Other specific joint derangements
0.710 0.290 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.710 0.290 0.000
H80-H83 Diseases of inner ear
0.710 0.290 0.000
H65-H75 Diseases of middle ear and mastoid
0.709 0.291 0.000
F41.8 Other specified anxiety disorders
0.708 0.292 0.000
F41.3 Other mixed anxiety disorders
0.708 0.292 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.707 0.293 0.000
I44.6 Other and unspecified fascicular block
0.706 0.294 0.000
M25.0 Haemarthrosis
0.706 0.294 0.000
F43.2 Adjustment disorders
0.705 0.295 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.703 0.297 0.000
S01.4 Open wound of cheek and temporomandibular area
0.702 0.298 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.701 0.299 0.000
Q80-Q89 Other congenital malformations
0.701 0.299 0.000
F60-F69 Disorders of adult personality and behaviour
0.700 0.299 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.700 0.300 0.000
I47.0 Reentry ventricular arrhythmia
0.699 0.301 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.698 0.302 0.000
V20-V29 Motorcycle rider injured in transport accident
0.697 0.302 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.697 0.303 0.000
I45.8 Other specified conduction disorders
0.695 0.304 0.000
I45.4 Nonspecific intraventricular block
0.695 0.304 0.000
I45.3 Trifascicular block
0.695 0.304 0.000
I45.0 Right fascicular block
0.695 0.304 0.000
G40.8 Other epilepsy
0.694 0.306 0.000
S92.3 Fracture of metatarsal bone
0.694 0.306 0.000
M25.57 Pain in joint (Ankle and foot)
0.694 0.306 0.000
I49.2 Junctional premature depolarisation
0.694 0.306 0.000
S81.8 Open wound of other parts of lower leg
0.692 0.307 0.000
M25.9 Joint disorder, unspecified
0.692 0.308 0.000
S32.0 Fracture of lumbar vertebra
0.692 0.308 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.692 0.308 0.000
M32 Systemic lupus erythematosus
0.692 0.308 0.000
M30 Polyarteritis nodosa and related conditions
0.692 0.308 0.000
B37.8 Candidiasis of other sites
0.691 0.309 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.690 0.310 0.000
Chapter VII Diseases of the eye and adnexa
0.688 0.312 0.000
Q00-Q07 Congenital malformations of the nervous system
0.687 0.313 0.000
I34 Nonrheumatic mitral valve disorders
0.686 0.314 0.000
T91.3 Sequelae of injury of spinal cord
0.684 0.316 0.000
G44 Other headache syndromes
0.684 0.316 0.000
S01.7 Multiple open wounds of head
0.684 0.316 0.000
F20 Schizophrenia
0.684 0.316 0.000
I44.3 Other and unspecified atrioventricular block
0.684 0.316 0.000
G91.9 Hydrocephalus, unspecified
0.683 0.317 0.000
M23.1 Discoid meniscus (congenital)
0.683 0.317 0.000
M23.0 Cystic meniscus
0.683 0.317 0.000
S67 Crushing injury of wrist and hand
0.682 0.318 0.000
I31 Other diseases of pericardium
0.682 0.318 0.000
Q27 Other congenital malformations of peripheral vascular system
0.682 0.318 0.000
S00.5 Superficial injury of lip and oral cavity
0.681 0.319 0.000
S00.4 Superficial injury of ear
0.681 0.319 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.681 0.319 0.000
M25.87 Other specified joint disorders (Ankle and foot)
0.679 0.321 0.000
L50-L54 Urticaria and erythema
0.679 0.321 0.000
O86 Other puerperal infections
0.679 0.321 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.679 0.321 0.000
L10-L14 Bullous disorders
0.678 0.322 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.676 0.324 0.000
M23.37 Other meniscus derangements-Capsular lig
0.676 0.324 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.676 0.324 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.675 0.324 0.000
Q35-Q37 Cleft lip and cleft palate
0.675 0.324 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.675 0.324 0.000
I44.5 Left posterior fascicular block
0.675 0.324 0.000
I44.4 Left anterior fascicular block
0.675 0.324 0.000
G30-G32 Other degenerative diseases of the nervous system
0.675 0.325 0.000
S64.4 Injury of digital nerve of other finger
0.675 0.325 0.000
Q28.0 Arteriovenous malformation of precerebral vessels
0.675 0.325 0.000
S69 Other and unspecified injuries of wrist and hand
0.675 0.325 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.674 0.326 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.674 0.326 0.000
O90 Complications of the puerperium, not elsewhere classified
0.673 0.327 0.000
M43 Other deforming dorsopathies
0.673 0.327 0.000
B37.9 Candidiasis, unspecified
0.672 0.328 0.000
L75 Apocrine sweat disorders
0.671 0.329 0.000
L74 Eccrine sweat disorders
0.671 0.329 0.000
L70 Acne
0.671 0.329 0.000
L68 Hypertrichosis
0.671 0.329 0.000
L67 Hair colour and hair shaft abnormalities
0.671 0.329 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.671 0.329 0.000
L65 Other nonscarring hair loss
0.671 0.329 0.000
L64 Androgenic alopecia
0.671 0.329 0.000
L63 Alopecia areata
0.671 0.329 0.000
L62 Nail disorders in diseases classified elsewhere
0.671 0.329 0.000
M25.2 Flail joint
0.671 0.329 0.000
M25.1 Fistula of joint
0.671 0.329 0.000
M33.2 Polymyositis
0.671 0.329 0.000
M00-M03 Infectious arthropathies
0.670 0.330 0.000
F42 Obsessive-compulsive disorder
0.670 0.330 0.000
W15.8 Other specified place
0.669 0.331 0.000
I30 Acute pericarditis
0.669 0.331 0.000
F80-F89 Disorders of psychological development
0.666 0.334 0.000
S62.4 Multiple fractures of metacarpal bones
0.666 0.334 0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.666 0.334 0.000
S00.1 Contusion of eyelid and periocular area
0.666 0.334 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.665 0.335 0.000
S65 Injury of blood vessels at wrist and hand level
0.665 0.335 0.000
G25 Other extrapyramidal and movement disorders
0.665 0.335 0.000
S51 Open wound of forearm
0.664 0.336 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.664 0.336 0.000
W07.0 Home
0.664 0.336 0.000
Q50-Q56 Congenital malformations of genital organs
0.663 0.337 0.000
L93 Lupus erythematosus
0.663 0.337 0.000
O43 Placental disorders
0.663 0.337 0.000
F52.2 Failure of genital response
0.663 0.337 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.662 0.337 0.000
S05.8 Other injuries of eye and orbit
0.662 0.338 0.000
X60-X84 Intentional self-harm
0.662 0.338 0.000
W10 Fall on and from stairs and steps
0.661 0.339 0.000
S80.8 Other superficial injuries of lower leg
0.661 0.339 0.000
S60 Superficial injury of wrist and hand
0.661 0.339 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.660 0.340 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.660 0.340 0.000
S03.2 Dislocation of tooth
0.658 0.342 0.000
I42.9 Cardiomyopathy, unspecified
0.658 0.342 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.656 0.344 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.655 0.344 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.655 0.345 0.000
F02 Dementia in other diseases classified elsewhere
0.655 0.345 0.000
F09 Unspecified organic or symptomatic mental disorder
0.655 0.345 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.655 0.345 0.000
F31 Bipolar affective disorder
0.653 0.347 0.000
H53-H54 Visual disturbances and blindness
0.652 0.348 0.000
L80 Vitiligo
0.651 0.349 0.000
L91.8 Other hypertrophic disorders of skin
0.651 0.349 0.000
M94 Other disorders of cartilage
0.651 0.349 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.650 0.350 0.000
M21.1 Varus deformity, not elsewhere classified
0.649 0.351 0.000
L83 Acanthosis nigricans
0.647 0.353 0.000
L94 Other localised connective tissue disorders
0.647 0.353 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.647 0.353 0.000
S06.4 Epidural haemorrhage
0.647 0.353 0.000
M33.1 Other dermatomyositis
0.646 0.354 0.000
I45.5 Other specified heart block
0.645 0.355 0.000
B65-B83 Helminthiases
0.645 0.355 0.000
F00 Dementia in Alzheimer's disease
0.644 0.356 0.000
I49.1 Atrial premature depolarisation
0.644 0.356 0.000
M25.76 Osteophyte (Lower leg)
0.644 0.356 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.644 0.356 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.644 0.356 0.000
I61.5 Intracerebral haemorrhage, intraventricular
0.644 0.356 0.000
M48 Other spondylopathies
0.643 0.357 0.000
I42.8 Other cardiomyopathies
0.643 0.357 0.000
B15-B19 Viral hepatitis
0.642 0.357 0.000
O44 Placenta praevia
0.642 0.358 0.000
I49.8 Other specified cardiac arrhythmias
0.641 0.359 0.000
S68 Traumatic amputation of wrist and hand
0.641 0.359 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.639 0.361 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.639 0.361 0.000
M41.9 Scoliosis, unspecified
0.638 0.362 0.000
F23 Acute and transient psychotic disorders
0.636 0.364 0.000
O36.8 Maternal care for other specified foetal problems
0.636 0.364 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.635 0.365 0.000
S88 Traumatic amputation of lower leg
0.634 0.366 0.000
S87 Crushing injury of lower leg
0.634 0.366 0.000
S86 Injury of muscle and tendon at lower leg level
0.634 0.366 0.000
S85 Injury of blood vessels at lower leg level
0.634 0.366 0.000
S84 Injury of nerves at lower leg level
0.634 0.366 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.634 0.366 0.000
S02.7 Multiple fractures involving skull and facial bones
0.634 0.366 0.000
S62.61 Fracture of other finger (open)
0.634 0.366 0.000
S92.30 Fracture of metatarsal bone (closed)
0.634 0.366 0.000
U80 Agent resistant to penicillin and related antibiotics
0.634 0.366 0.000
I62 Other nontraumatic intracranial haemorrhage
0.633 0.367 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.633 0.367 0.000
S37 Injury of urinary and pelvic organs
0.633 0.367 0.000
S36 Injury of intra-abdominal organs
0.633 0.367 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.633 0.367 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.633 0.367 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.633 0.367 0.000
S31 Open wound of abdomen, lower back and pelvis
0.633 0.367 0.000
M25.79 Osteophyte (Site unspecified)
0.633 0.367 0.000
M25.73 Osteophyte (Forearm)
0.633 0.367 0.000
M25.72 Osteophyte (Upper arm)
0.633 0.367 0.000
M25.70 Osteophyte (Multiple sites)
0.633 0.367 0.000
S00.0 Superficial injury of scalp
0.633 0.367 0.000
O45 Premature separation of placenta [abruptio placentae]
0.633 0.367 0.000
O33 Maternal care for known or suspected disproportion
0.633 0.367 0.000
O31 Complications specific to multiple gestation
0.633 0.367 0.000
T93 Sequelae of injuries of lower limb
0.632 0.367 0.000
M21.3 Wrist or foot drop (acquired)
0.632 0.368 0.000
L60.9 Nail disorder, unspecified
0.631 0.369 0.000
L60.5 Yellow nail syndrome
0.631 0.369 0.000
L60.4 Beau's lines
0.631 0.369 0.000
L60.3 Nail dystrophy
0.631 0.369 0.000
L60.2 Onychogryphosis
0.631 0.369 0.000
L60.1 Onycholysis
0.631 0.369 0.000
M21.6 Other acquired deformities of ankle and foot
0.630 0.370 0.000
M22 Disorders of patella
0.630 0.370 0.000
G41 Status epilepticus
0.629 0.370 0.000
O30 Multiple gestation
0.629 0.370 0.000
M21.2 Flexion deformity
0.629 0.371 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.629 0.371 0.000
M25.78 Osteophyte (Other)
0.629 0.371 0.000
S02.1 Fracture of base of skull
0.627 0.373 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.626 0.374 0.000
V10-V19 Pedal cyclist injured in transport accident
0.626 0.374 0.000
S32.00 Fracture of lumbar vertebra (closed)
0.625 0.375 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.624 0.376 0.000
S06.8 Other intracranial injuries
0.624 0.376 0.000
M86-M90 Other osteopathies
0.622 0.378 0.000
S62.60 Fracture of other finger (closed)
0.622 0.378 0.000
S06.9 Intracranial injury, unspecified
0.622 0.378 0.000
S06.7 Intracranial injury with prolonged coma
0.622 0.378 0.000
S06.3 Focal brain injury
0.622 0.378 0.000
S06.1 Traumatic cerebral oedema
0.622 0.378 0.000
S98 Traumatic amputation of ankle and foot
0.622 0.378 0.000
S97 Crushing injury of ankle and foot
0.622 0.378 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.622 0.378 0.000
S95 Injury of blood vessels at ankle and foot level
0.622 0.378 0.000
S94 Injury of nerves at ankle and foot level
0.622 0.378 0.000
G11 Hereditary ataxia
0.622 0.378 0.000
S92.4 Fracture of great toe
0.621 0.379 0.000
S02.8 Fractures of other skull and facial bones
0.621 0.379 0.000
Q21 Congenital malformations of cardiac septa
0.621 0.379 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.621 0.379 0.000
T23 Burn and corrosion of wrist and hand
0.620 0.379 0.000
S06.2 Diffuse brain injury
0.620 0.380 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.620 0.380 0.000
T98 Sequelae of other and unspecified effects of external causes
0.620 0.380 0.000
T95 Sequelae of burns, corrosions and frostbite
0.620 0.380 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.620 0.380 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.620 0.380 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.620 0.380 0.000
F06.7 Mild cognitive disorder
0.620 0.380 0.000
H55-H59 Other disorders of eye and adnexa
0.620 0.380 0.000
O23 Infections of genito-urinary tract in pregnancy
0.620 0.380 0.000
G70-G73 Diseases of myoneural junction and muscle
0.620 0.380 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.620 0.380 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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