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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs9451906
log Bayes Factor = 28.3252
Chromosome 6   position 65,240,905  (GRCh37) Explore rs9451906 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.999 0.001 0.000
E78.0 Pure hypercholesterolaemia
0.999 0.001 0.000
O60-O75 Complications of labour and delivery
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.998 0.002 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.997 0.003 0.000
I25.2 Old myocardial infarction
0.997 0.003 0.000
E10-E14 Diabetes mellitus
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.994 0.006 0.000
I21 Acute myocardial infarction
0.990 0.010 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.990 0.010 0.000
N17-N19 Renal failure
0.987 0.013 0.000
E83 Disorders of mineral metabolism
0.987 0.013 0.000
I20 Angina pectoris
0.987 0.013 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.986 0.014 0.000
Chapter V Mental and behavioural disorders
0.986 0.014 0.000
I21.9 Acute myocardial infarction, unspecified
0.984 0.016 0.000
E11 Non-insulin-dependent diabetes mellitus
0.984 0.016 0.000
N10-N16 Renal tubulo-interstitial diseases
0.981 0.019 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.971 0.029 0.000
R07.4 Chest pain, unspecified
0.971 0.029 0.000
R07 Pain in throat and chest
0.970 0.030 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.969 0.031 0.000
F30-F39 Mood [affective] disorders
0.969 0.031 0.000
N20-N23 Urolithiasis
0.968 0.032 0.000
E83.5 Disorders of calcium metabolism
0.968 0.032 0.000
E11.9 Without complications
0.967 0.033 0.000
I20.9 Angina pectoris, unspecified
0.965 0.035 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.964 0.036 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.961 0.039 0.000
N20 Calculus of kidney and ureter
0.951 0.049 0.000
E10 Insulin-dependent diabetes mellitus
0.951 0.049 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.950 0.050 0.000
N18 Chronic renal failure
0.949 0.051 0.000
N13 Obstructive and reflux uropathy
0.948 0.052 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.943 0.057 0.000
N20.1 Calculus of ureter
0.943 0.057 0.000
Z50 Care involving use of rehabilitation procedures
0.942 0.058 0.000
Chapter I Certain infectious and parasitic diseases
0.941 0.059 0.000
I25.1 Atherosclerotic heart disease
0.939 0.061 0.000
I60-I69 Cerebrovascular diseases
0.935 0.065 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.931 0.069 0.000
F31 Bipolar affective disorder
0.924 0.076 0.000
M50-M54 Other dorsopathies
0.919 0.081 0.000
N17 Acute renal failure
0.916 0.084 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.916 0.084 0.000
Z45 Adjustment and management of implanted device
0.909 0.091 0.000
N00-N08 Glomerular diseases
0.902 0.098 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.902 0.098 0.000
Z50.1 Other physical therapy
0.901 0.099 0.000
N18.9 Chronic renal failure, unspecified
0.900 0.100 0.000
I95 Hypotension
0.900 0.100 0.000
M80-M85 Disorders of bone density and structure
0.897 0.103 0.000
O72 Postpartum haemorrhage
0.894 0.106 0.000
I30-I52 Other forms of heart disease
0.892 0.108 0.000
S60-S69 Injuries to the wrist and hand
0.892 0.108 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.891 0.109 0.000
E10.9 Without complications
0.890 0.110 0.000
O63 Long labour
0.890 0.110 0.000
Chapter VII Diseases of the eye and adnexa
0.883 0.117 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.881 0.119 0.000
F33 Recurrent depressive disorder
0.880 0.120 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.878 0.122 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.877 0.123 0.000
I20.0 Unstable angina
0.877 0.123 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.875 0.125 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.875 0.125 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.871 0.129 0.000
O70 Perineal laceration during delivery
0.871 0.129 0.000
I73 Other peripheral vascular diseases
0.869 0.131 0.000
I22 Subsequent myocardial infarction
0.867 0.133 0.000
N17.9 Acute renal failure, unspecified
0.865 0.135 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.865 0.135 0.000
E83.4 Disorders of magnesium metabolism
0.864 0.136 0.000
R07.3 Other chest pain
0.863 0.137 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.861 0.139 0.000
Z36 Antenatal screening
0.861 0.139 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.859 0.141 0.000
F31.9 Bipolar affective disorder, unspecified
0.858 0.142 0.000
I67 Other cerebrovascular diseases
0.857 0.143 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.856 0.144 0.000
I95.9 Hypotension, unspecified
0.855 0.145 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.852 0.148 0.000
S80-S89 Injuries to the knee and lower leg
0.850 0.150 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.849 0.151 0.000
Z45.8 Adjustment and management of other implanted devices
0.846 0.154 0.000
A30-A49 Other bacterial diseases
0.843 0.157 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.840 0.159 0.000
Z34 Supervision of normal pregnancy
0.840 0.160 0.000
R01 Cardiac murmurs and other cardiac sounds
0.838 0.162 0.000
M54 Dorsalgia
0.836 0.164 0.000
N18.4 Chronic kidney disease, stage 4
0.831 0.169 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.831 0.169 0.000
E11.3 With ophthalmic complications
0.831 0.169 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.830 0.170 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.829 0.171 0.000
I26 Pulmonary embolism
0.828 0.172 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.828 0.172 0.000
Z95.1 Presence of aortocoronary bypass graft
0.827 0.173 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.826 0.174 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.825 0.175 0.000
M15-M19 Arthrosis
0.825 0.175 0.000
Z39 Postpartum care and examination
0.819 0.181 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.818 0.182 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.816 0.184 0.000
S40-S49 Injuries to the shoulder and upper arm
0.813 0.187 0.000
I63 Cerebral infarction
0.813 0.187 0.000
S00-S09 Injuries to the head
0.812 0.188 0.000
N03 Chronic nephritic syndrome
0.809 0.191 0.000
O70.0 First degree perineal laceration during delivery
0.808 0.192 0.000
I73.9 Peripheral vascular disease, unspecified
0.806 0.194 0.000
O00-O08 Pregnancy with abortive outcome
0.801 0.199 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.801 0.199 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.799 0.201 0.000
O72.1 Other immediate postpartum haemorrhage
0.799 0.201 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.798 0.202 0.000
M05-M14 Inflammatory polyarthropathies
0.798 0.202 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.797 0.203 0.000
M80 Osteoporosis with pathological fracture
0.797 0.203 0.000
I49 Other cardiac arrhythmias
0.791 0.209 0.000
O66 Other obstructed labour
0.791 0.209 0.000
O62 Abnormalities of forces of labour
0.786 0.214 0.000
Chapter VI Diseases of the nervous system
0.785 0.215 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.784 0.216 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.783 0.217 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.782 0.218 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.782 0.218 0.000
I67.9 Cerebrovascular disease, unspecified
0.781 0.219 0.000
E20-E35 Disorders of other endocrine glands
0.780 0.219 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.777 0.222 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.777 0.223 0.000
S10-S19 Injuries to the neck
0.776 0.224 0.000
M45-M49 Spondylopathies
0.776 0.224 0.000
Z60 Problems related to social environment
0.775 0.224 0.000
I25.5 Ischaemic cardiomyopathy
0.775 0.225 0.000
F33.9 Recurrent depressive disorder, unspecified
0.774 0.226 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.773 0.227 0.000
Z36.8 Other antenatal screening
0.772 0.228 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.771 0.229 0.000
S70-S79 Injuries to the hip and thigh
0.771 0.229 0.000
Z37 Outcome of delivery
0.770 0.230 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.769 0.231 0.000
O63.0 Prolonged first stage (of labour)
0.767 0.233 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.766 0.234 0.000
O16 Unspecified maternal hypertension
0.766 0.234 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.765 0.235 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.765 0.235 0.000
M50 Cervical disk disorders
0.764 0.236 0.000
M86-M90 Other osteopathies
0.763 0.237 0.000
F99-F99 Unspecified mental disorder
0.761 0.239 0.000
N19 Unspecified renal failure
0.760 0.240 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.758 0.242 0.000
E40-E46 Malnutrition
0.757 0.243 0.000
M17 Gonarthrosis [arthrosis of knee]
0.757 0.243 0.000
I47 Paroxysmal tachycardia
0.754 0.246 0.000
H30-H36 Disorders of choroid and retina
0.753 0.247 0.000
I80 Phlebitis and thrombophlebitis
0.753 0.247 0.000
Chapter XXII Codes for special purposes
0.752 0.247 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.752 0.248 0.000
F60-F69 Disorders of adult personality and behaviour
0.751 0.249 0.000
I38 Endocarditis, valve unspecified
0.750 0.250 0.000
A80-A89 Viral infections of the central nervous system
0.750 0.250 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.750 0.250 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.750 0.250 0.000
Z52 Donors of organs and tissues
0.749 0.250 0.000
Z32 Pregnancy examination and test
0.749 0.251 0.000
E10.4 With neurological complications
0.747 0.252 0.000
R01.1 Cardiac murmur, unspecified
0.745 0.255 0.000
M40-M43 Deforming dorsopathies
0.744 0.256 0.000
I20.1 Angina pectoris with documented spasm
0.743 0.256 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.743 0.257 0.000
N03.9 Unspecified
0.742 0.258 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.741 0.259 0.000
M65-M68 Disorders of synovium and tendon
0.740 0.260 0.000
N13.4 Hydroureter
0.738 0.261 0.000
E50-E64 Other nutritional deficiencies
0.738 0.262 0.000
F32 Depressive episode
0.738 0.262 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.737 0.263 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.736 0.263 0.000
A41 Other septicaemia
0.736 0.264 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.735 0.265 0.000
E14 Unspecified diabetes mellitus
0.735 0.265 0.000
S20-S29 Injuries to the thorax
0.734 0.266 0.000
Z02 Examination and encounter for administrative purposes
0.734 0.266 0.000
O63.1 Prolonged second stage (of labour)
0.732 0.268 0.000
Z54 Convalescence
0.731 0.268 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.730 0.270 0.000
B95-B98 Bacterial, viral and other infectious agents
0.730 0.270 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.728 0.272 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.728 0.272 0.000
H55-H59 Other disorders of eye and adnexa
0.728 0.272 0.000
N99-N99 Other disorders of the genitourinary system
0.728 0.272 0.000
S90-S99 Injuries to the ankle and foot
0.728 0.272 0.000
I45 Other conduction disorders
0.728 0.272 0.000
I69 Sequelae of cerebrovascular disease
0.727 0.272 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.727 0.273 0.000
E89.0 Postprocedural hypothyroidism
0.726 0.274 0.000
M54.2 Cervicalgia
0.726 0.274 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.725 0.275 0.000
Z50.8 Care involving use of rehabilitation procedures
0.725 0.275 0.000
E10.3 With ophthalmic complications
0.724 0.276 0.000
N20.2 Calculus of kidney with calculus of ureter
0.724 0.276 0.000
Z34.8 Supervision of other normal pregnancy
0.723 0.277 0.000
E10.1 With ketoacidosis
0.722 0.278 0.000
Z50.2 Alcohol rehabilitation
0.721 0.279 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.721 0.279 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.721 0.279 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.721 0.279 0.000
M84 Disorders of continuity of bone
0.720 0.280 0.000
Chapter XI Diseases of the digestive system
0.719 0.281 0.000
E11.2 With renal complications
0.719 0.281 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.719 0.281 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.719 0.281 0.000
O42 Premature rupture of membranes
0.718 0.282 0.000
I77 Other disorders of arteries and arterioles
0.718 0.282 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E88 Other metabolic disorders
0.717 0.283 0.000
E85 Amyloidosis
0.717 0.283 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E74 Other disorders of carbohydrate metabolism
0.717 0.283 0.000
E73 Lactose intolerance
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
A00-A09 Intestinal infectious diseases
0.717 0.283 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.716 0.284 0.000
E78.8 Other disorders of lipoprotein metabolism
0.716 0.284 0.000
E78.6 Lipoprotein deficiency
0.716 0.284 0.000
E78.4 Other hyperlipidaemia
0.716 0.284 0.000
E78.3 Hyperchylomicronaemia
0.716 0.284 0.000
E78.2 Mixed hyperlipidaemia
0.716 0.284 0.000
E78.1 Pure hyperglyceridaemia
0.716 0.284 0.000
O74 Complications of anaesthesia during labour and delivery
0.716 0.284 0.000
O73 Retained placenta and membranes, without haemorrhage
0.716 0.284 0.000
O71 Other obstetric trauma
0.716 0.284 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.716 0.284 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.716 0.284 0.000
O61 Failed induction of labour
0.716 0.284 0.000
O60 Preterm delivery
0.716 0.284 0.000
E13 Other specified diabetes mellitus
0.715 0.285 0.000
E12 Malnutrition-related diabetes mellitus
0.715 0.285 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.714 0.286 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.714 0.286 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.714 0.286 0.000
Z35 Supervision of high-risk pregnancy
0.713 0.287 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.713 0.287 0.000
T79-T79 Certain early complications of trauma
0.713 0.287 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
T66-T78 Other and unspecified effects of external causes
0.713 0.287 0.000
B35-B49 Mycoses
0.711 0.289 0.000
O04 Medical abortion
0.711 0.289 0.000
I05-I09 Chronic rheumatic heart diseases
0.710 0.289 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.710 0.290 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.710 0.290 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.710 0.290 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.710 0.290 0.000
M91-M94 Chondropathies
0.710 0.290 0.000
M60-M63 Disorders of muscles
0.710 0.290 0.000
M00-M03 Infectious arthropathies
0.710 0.290 0.000
N18.3 Chronic kidney disease, stage 3
0.710 0.290 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.708 0.292 0.000
E83.8 Other disorders of mineral metabolism
0.708 0.292 0.000
E83.3 Disorders of phosphorus metabolism
0.708 0.292 0.000
E83.2 Disorders of zinc metabolism
0.708 0.292 0.000
E83.0 Disorders of copper metabolism
0.708 0.292 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.707 0.293 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.707 0.293 0.000
F80-F89 Disorders of psychological development
0.707 0.293 0.000
F70-F79 Mental retardation
0.707 0.293 0.000
E11.4 With neurological complications
0.706 0.294 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.706 0.294 0.000
Z39.0 Care and examination immediately after delivery
0.706 0.294 0.000
E11.8 With unspecified complications
0.706 0.294 0.000
E11.7 With multiple complications
0.706 0.294 0.000
E11.6 With other specified complications
0.706 0.294 0.000
E11.1 With ketoacidosis
0.706 0.294 0.000
E11.0 With coma
0.706 0.294 0.000
S61 Open wound of wrist and hand
0.706 0.294 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.705 0.295 0.000
I62 Other nontraumatic intracranial haemorrhage
0.705 0.295 0.000
I95.2 Hypotension due to drugs
0.705 0.295 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.704 0.296 0.000
B25-B34 Other viral diseases
0.704 0.296 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.703 0.297 0.000
N15 Other renal tubulo-interstitial diseases
0.703 0.297 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.703 0.297 0.000
N11 Chronic tubulo-interstitial nephritis
0.703 0.297 0.000
N10 Acute tubulo-interstitial nephritis
0.703 0.297 0.000
I49.9 Cardiac arrhythmia, unspecified
0.702 0.298 0.000
O48 Prolonged pregnancy
0.701 0.299 0.000
Z60.2 Living alone
0.700 0.300 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.699 0.301 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.698 0.302 0.000
R23 Other skin changes
0.698 0.302 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.697 0.302 0.000
E11.5 With peripheral circulatory complications
0.697 0.303 0.000
I73.0 Raynaud's syndrome
0.697 0.303 0.000
R05 Cough
0.697 0.303 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.696 0.303 0.000
I86 Varicose veins of other sites
0.696 0.304 0.000
Chapter XX External causes of morbidity and mortality
0.696 0.304 0.000
R07.1 Chest pain on breathing
0.695 0.304 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.695 0.305 0.000
F38 Other mood [affective] disorders
0.695 0.305 0.000
F34 Persistent mood [affective] disorders
0.695 0.305 0.000
F30 Manic episode
0.695 0.305 0.000
F39 Unspecified mood [affective] disorder
0.695 0.305 0.000
S62 Fracture at wrist and hand level
0.694 0.306 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.694 0.306 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.694 0.306 0.000
I81 Portal vein thrombosis
0.694 0.306 0.000
R06 Abnormalities of breathing
0.693 0.307 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.693 0.307 0.000
Z33 Pregnant state, incidental
0.692 0.307 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.691 0.309 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.691 0.309 0.000
N02 Recurrent and persistent haematuria
0.690 0.309 0.000
O80-O84 Delivery
0.690 0.309 0.000
Z38 Liveborn infants according to place of birth
0.689 0.311 0.000
Z31 Procreative management
0.689 0.311 0.000
S42 Fracture of shoulder and upper arm
0.689 0.311 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.688 0.312 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.688 0.312 0.000
I67.8 Other specified cerebrovascular diseases
0.687 0.313 0.000
O43 Placental disorders
0.687 0.313 0.000
I71 Aortic aneurysm and dissection
0.687 0.313 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.686 0.314 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.686 0.314 0.000
A49 Bacterial infection of unspecified site
0.685 0.315 0.000
M53 Other dorsopathies, not elsewhere classified
0.684 0.315 0.000
M06 Other rheumatoid arthritis
0.684 0.316 0.000
Z89 Acquired absence of limb
0.683 0.317 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.683 0.317 0.000
M54.5 Low back pain
0.683 0.317 0.000
Z57 Occupational exposure to risk-factors
0.683 0.317 0.000
S83.2 Tear of meniscus, current
0.682 0.318 0.000
N20.9 Urinary calculus, unspecified
0.682 0.318 0.000
M16 Coxarthrosis [arthrosis of hip]
0.682 0.318 0.000
E10.8 With unspecified complications
0.682 0.318 0.000
E10.7 With multiple complications
0.682 0.318 0.000
E10.6 With other specified complications
0.682 0.318 0.000
E10.5 With peripheral circulatory complications
0.682 0.318 0.000
E10.2 With renal complications
0.682 0.318 0.000
E10.0 With coma
0.682 0.318 0.000
M54.4 Lumbago with sciatica
0.681 0.319 0.000
Z49 Care involving dialysis
0.681 0.319 0.000
Z44 Fitting and adjustment of external prosthetic device
0.681 0.319 0.000
I61 Intracerebral haemorrhage
0.681 0.319 0.000
L40-L45 Papulosquamous disorders
0.681 0.319 0.000
N18.8 Other chronic renal failure
0.680 0.320 0.000
N18.2 Chronic kidney disease, stage 2
0.680 0.320 0.000
N18.1 Chronic kidney disease, stage 1
0.680 0.320 0.000
N13.8 Other obstructive and reflux uropathy
0.679 0.321 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.679 0.321 0.000
N13.6 Pyonephrosis
0.679 0.321 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.679 0.321 0.000
N13.3 Other and unspecified hydronephrosis
0.679 0.321 0.000
Chapter II Neoplasms
0.679 0.321 0.000
Z41 Procedures for purposes other than remedying health state
0.679 0.321 0.000
N23 Unspecified renal colic
0.678 0.322 0.000
S89 Other and unspecified injuries of lower leg
0.678 0.322 0.000
M85 Other disorders of bone density and structure
0.677 0.323 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.676 0.324 0.000
I99 Other and unspecified disorders of circulatory system
0.676 0.324 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.676 0.324 0.000
I24 Other acute ischaemic heart diseases
0.675 0.324 0.000
Z50.6 Orthoptic training
0.675 0.325 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.675 0.325 0.000
Z50.3 Drug rehabilitation
0.675 0.325 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.675 0.325 0.000
E83.1 Disorders of iron metabolism
0.675 0.325 0.000
B99-B99 Other infectious diseases
0.675 0.325 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.675 0.325 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.675 0.325 0.000
B65-B83 Helminthiases
0.675 0.325 0.000
B50-B64 Protozoal diseases
0.675 0.325 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.675 0.325 0.000
B15-B19 Viral hepatitis
0.675 0.325 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.675 0.325 0.000
A75-A79 Rickettsioses
0.675 0.325 0.000
A70-A74 Other diseases caused by chlamydiae
0.675 0.325 0.000
A65-A69 Other spirochaetal diseases
0.675 0.325 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.675 0.325 0.000
A20-A28 Certain zoonotic bacterial diseases
0.675 0.325 0.000
A15-A19 Tuberculosis
0.675 0.325 0.000
Z96 Presence of other functional implants
0.673 0.327 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.673 0.327 0.000
I78 Diseases of capillaries
0.672 0.328 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.672 0.328 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.671 0.329 0.000
M17.9 Gonarthrosis, unspecified
0.671 0.329 0.000
K22 Other diseases of oesophagus
0.671 0.329 0.000
S69 Other and unspecified injuries of wrist and hand
0.670 0.329 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.670 0.330 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.670 0.330 0.000
Chapter VIII Diseases of the ear and mastoid process
0.670 0.330 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.669 0.330 0.000
Z02.8 Other examinations for administrative purposes
0.669 0.331 0.000
I46 Cardiac arrest
0.669 0.331 0.000
I95.1 Orthostatic hypotension
0.668 0.332 0.000
M20-M25 Other joint disorders
0.668 0.332 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.667 0.333 0.000
I72 Other aneurysm
0.667 0.333 0.000
I70 Atherosclerosis
0.667 0.333 0.000
Z50.0 Cardiac rehabilitation
0.667 0.333 0.000
I47.1 Supraventricular tachycardia
0.667 0.333 0.000
L50-L54 Urticaria and erythema
0.667 0.333 0.000
H35 Other retinal disorders
0.664 0.336 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.664 0.336 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.664 0.336 0.000
Z50.5 Speech therapy
0.664 0.336 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.664 0.336 0.000
Z45.2 Adjustment and management of vascular access device
0.663 0.337 0.000
F31.8 Other bipolar affective disorders
0.662 0.337 0.000
F31.7 Bipolar affective disorder, currently in remission
0.662 0.337 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.662 0.337 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.662 0.337 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.662 0.337 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.662 0.337 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.662 0.337 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.662 0.337 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.662 0.338 0.000
R26 Abnormalities of gait and mobility
0.662 0.338 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.661 0.339 0.000
S64 Injury of nerves at wrist and hand level
0.661 0.339 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.661 0.339 0.000
S01 Open wound of head
0.661 0.339 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.660 0.340 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.658 0.342 0.000
N17.8 Other acute renal failure
0.657 0.343 0.000
N17.2 Acute renal failure with medullary necrosis
0.657 0.343 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.657 0.343 0.000
N17.0 Acute renal failure with tubular necrosis
0.657 0.343 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.657 0.343 0.000
O97 Death from sequelae of direct obstetric causes
0.657 0.343 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.657 0.343 0.000
O95 Obstetric death of unspecified cause
0.657 0.343 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.657 0.343 0.000
R07.0 Pain in throat
0.657 0.343 0.000
I35 Nonrheumatic aortic valve disorders
0.657 0.343 0.000
I51 Complications and ill-defined descriptions of heart disease
0.654 0.346 0.000
I10-I15 Hypertensive diseases
0.653 0.347 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.652 0.348 0.000
Z45.3 Adjustment and management of implanted hearing device
0.652 0.348 0.000
Z45.1 Adjustment and management of infusion pump
0.652 0.348 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.651 0.349 0.000
K31 Other diseases of stomach and duodenum
0.649 0.351 0.000
E29 Testicular dysfunction
0.649 0.351 0.000
M54.22 Cervicalgia (Cervical region)
0.647 0.353 0.000
N21 Calculus of lower urinary tract
0.647 0.353 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.647 0.353 0.000
N06 Isolated proteinuria with specified morphological lesion
0.647 0.353 0.000
N05 Unspecified nephritic syndrome
0.647 0.353 0.000
N04 Nephrotic syndrome
0.647 0.353 0.000
N01 Rapidly progressive nephritic syndrome
0.647 0.353 0.000
N00 Acute nephritic syndrome
0.647 0.353 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.647 0.353 0.000
O04.9 Complete or unspecified, without complication
0.646 0.354 0.000
Z13 Special screening examination for other diseases and disorders
0.646 0.354 0.000
I95.8 Other hypotension
0.645 0.355 0.000
I95.0 Idiopathic hypotension
0.645 0.355 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.644 0.356 0.000
M83 Adult osteomalacia
0.643 0.357 0.000
M82 Osteoporosis in diseases classified elsewhere
0.643 0.357 0.000
Z94 Transplanted organ and tissue status
0.643 0.357 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.643 0.357 0.000
Z37.0 Single live birth
0.642 0.358 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.642 0.358 0.000
I33 Acute and subacute endocarditis
0.642 0.358 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.641 0.358 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.641 0.359 0.000
I74 Arterial embolism and thrombosis
0.641 0.359 0.000
O72.3 Postpartum coagulation defects
0.641 0.359 0.000
O72.0 Third-stage haemorrhage
0.641 0.359 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.640 0.360 0.000
E78.5 Hyperlipidaemia, unspecified
0.640 0.360 0.000
I52 Other heart disorders in diseases classified elsewhere
0.639 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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