TreeWAS – Variant ID: rs9686661

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11.9 Without complications	0.476	0.524	0.000
E11 Non-insulin-dependent diabetes mellitus	0.467	0.533	0.000
E11.3 With ophthalmic complications	0.457	0.543	0.000
E10-E14 Diabetes mellitus	0.402	0.598	0.000
E14 Unspecified diabetes mellitus	0.390	0.610	0.000
E14.9 Without complications	0.386	0.614	0.000
E11.8 With unspecified complications	0.381	0.619	0.000
E11.2 With renal complications	0.345	0.655	0.000
E11.5 With peripheral circulatory complications	0.339	0.661	0.000
E11.7 With multiple complications	0.335	0.665	0.000
E11.6 With other specified complications	0.333	0.667	0.000
E13 Other specified diabetes mellitus	0.326	0.674	0.000
E14.6 With other specified complications	0.309	0.691	0.000
E11.0 With coma	0.300	0.699	0.000
E14.1 With ketoacidosis	0.290	0.709	0.000
E12 Malnutrition-related diabetes mellitus	0.288	0.712	0.000
E11.4 With neurological complications	0.288	0.712	0.000
E14.7 With multiple complications	0.279	0.720	0.000
E14.0 With coma	0.279	0.720	0.000
E14.8 With unspecified complications	0.274	0.726	0.000
E11.1 With ketoacidosis	0.273	0.727	0.000
E13.9 Without complications	0.272	0.728	0.000
E14.5 With peripheral circulatory complications	0.272	0.728	0.000
E14.2 Withrenal complications	0.270	0.729	0.000
E14.4 With neurological complications	0.266	0.734	0.000
E13.8 With unspecified complications	0.234	0.766	0.000
E13.7 With multiple complications	0.234	0.766	0.000
E13.6 With other specified complications	0.234	0.766	0.000
E13.5 With peripheral circulatory complications	0.234	0.766	0.000
E13.4 With neurological complications	0.234	0.766	0.000
E13.3 With ophthalmic complications	0.234	0.766	0.000
E13.2 With renal complications	0.234	0.766	0.000
E13.1 With ketoacidosis	0.234	0.766	0.000
E13.0 With coma	0.234	0.766	0.000
E10 Insulin-dependent diabetes mellitus	0.221	0.779	0.000
E12.9 Without complications	0.207	0.793	0.000
E12.8 With unspecified complications	0.207	0.793	0.000
E12.7 With multiple complications	0.207	0.793	0.000
E12.6 With other specified complications	0.207	0.793	0.000
E12.5 With peripheral circulatory complications	0.207	0.793	0.000
E12.4 With neurological complications	0.207	0.793	0.000
E12.3 With ophthalmic complications	0.207	0.793	0.000
E12.2 With renal complications	0.207	0.793	0.000
E12.1 With ketoacidosis	0.207	0.793	0.000
E12.0 With coma	0.207	0.793	0.000
E10.9 Without complications	0.187	0.813	0.000
E14.3 With ophthalmic complications	0.184	0.816	0.000
E10.1 With ketoacidosis	0.174	0.826	0.000
E10.6 With other specified complications	0.161	0.839	0.000
E10.7 With multiple complications	0.159	0.841	0.000
E10.3 With ophthalmic complications	0.158	0.842	0.000
E10.5 With peripheral circulatory complications	0.147	0.853	0.000
E10.0 With coma	0.146	0.854	0.000
E10.8 With unspecified complications	0.137	0.862	0.000
E10.2 With renal complications	0.129	0.871	0.000
E10.4 With neurological complications	0.109	0.891	0.000
I10 Essential (primary) hypertension	0.074	0.926	0.000
H26.9 Cataract, unspecified	0.000	0.927	0.073
I25.1 Atherosclerotic heart disease	0.064	0.936	0.000
E78.0 Pure hypercholesterolaemia	0.062	0.938	0.000
I25 Chronic ischaemic heart disease	0.061	0.939	0.000
I25.5 Ischaemic cardiomyopathy	0.060	0.940	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.055	0.945	0.000
I25.4 Coronary artery aneurysm	0.052	0.948	0.000
I25.3 Aneurysm of heart	0.048	0.952	0.000
I20.9 Angina pectoris, unspecified	0.045	0.955	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.045	0.955	0.000
I20-I25 Ischaemic heart diseases	0.045	0.955	0.000
I25.6 Silent myocardial ischaemia	0.044	0.956	0.000
I20 Angina pectoris	0.043	0.957	0.000
E78.5 Hyperlipidaemia, unspecified	0.041	0.959	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.037	0.963	0.000
I21 Acute myocardial infarction	0.036	0.964	0.000
H26 Other cataract	0.000	0.964	0.036
I21.4 Acute subendocardial myocardial infarction	0.036	0.964	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.035	0.965	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.034	0.966	0.000
E78.2 Mixed hyperlipidaemia	0.034	0.966	0.000
I20.1 Angina pectoris with documented spasm	0.033	0.967	0.000
E78.8 Other disorders of lipoprotein metabolism	0.033	0.967	0.000
E78.6 Lipoprotein deficiency	0.033	0.967	0.000
E78.3 Hyperchylomicronaemia	0.032	0.967	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.032	0.968	0.000
I24 Other acute ischaemic heart diseases	0.032	0.968	0.000
I23 Certain current complications following acute myocardial infarction	0.032	0.968	0.000
H26.2 Complicated cataract	0.000	0.969	0.031
H26.1 Traumatic cataract	0.000	0.969	0.031
I24.8 Other forms of acute ischaemic heart disease	0.031	0.969	0.000
I20.0 Unstable angina	0.027	0.973	0.000
E78.1 Pure hyperglyceridaemia	0.026	0.973	0.000
H26.3 Drug-induced cataract	0.000	0.974	0.026
I21.X Presumed acute myicardial infaction (unconfirmed)	0.026	0.974	0.000
I10-I15 Hypertensive diseases	0.026	0.974	0.000
E78.4 Other hyperlipidaemia	0.026	0.974	0.000
H26.0 Infantile, juvenile and presenile cataract	0.000	0.975	0.024
I21.3 Acute transmural myocardial infarction of unspecified site	0.024	0.976	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.023	0.977	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.023	0.977	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.023	0.977	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.023	0.977	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.023	0.977	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.023	0.977	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.023	0.977	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.022	0.978	0.000
I23.8 Other current complications following acute myocardial infarction	0.022	0.978	0.000
H26.8 Other specified cataract	0.000	0.978	0.022
E70-E90 Metabolic disorders	0.022	0.978	0.000
I24.1 Dressler's syndrome	0.021	0.978	0.000
C80.9 Malignant neoplasm, unspecified	0.021	0.979	0.000
I15 Secondary hypertension	0.021	0.979	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.020	0.980	0.000
H26.4 After-cataract	0.000	0.980	0.020
I13 Hypertensive heart and renal disease	0.019	0.981	0.000
I20.8 Other forms of angina pectoris	0.019	0.981	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.018	0.982	0.000
I15.9 Seconday hypertension, unspecified	0.018	0.982	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.017	0.983	0.000
I22 Subsequent myocardial infarction	0.017	0.983	0.000
I21.9 Acute myocardial infarction, unspecified	0.017	0.983	0.000
E73 Lactose intolerance	0.016	0.983	0.000
E89.3 Postprocedural hypopituitarism	0.016	0.984	0.000
I12 Hypertensive renal disease	0.016	0.984	0.000
E83 Disorders of mineral metabolism	0.016	0.984	0.000
E84 Cystic fibrosis	0.016	0.984	0.000
E79 Disorders of purine and pyrimidine metabolism	0.016	0.984	0.000
E77 Disorders of glycoprotein metabolism	0.016	0.984	0.000
E76 Disorders of glycosaminoglycan metabolism	0.016	0.984	0.000
E72 Other disorders of amino-acid metabolism	0.016	0.984	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.016	0.984	0.000
E70 Disorders of aromatic amino-acid metabolism	0.016	0.984	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.016	0.984	0.000
E89.4 Postprocedural ovarian failure	0.015	0.984	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.015	0.984	0.000
E40-E46 Malnutrition	0.015	0.985	0.000
I15.8 Other secondary hypertension	0.015	0.985	0.000
I15.2 Hypertension secondary to endocrine disorders	0.015	0.985	0.000
I15.0 Renovascular hypertension	0.015	0.985	0.000
E83.1 Disorders of iron metabolism	0.015	0.985	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.014	0.985	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.014	0.986	0.000
E89.2 Postprocedural hypoparathyroidism	0.014	0.986	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.014	0.986	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.014	0.986	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.014	0.986	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.014	0.986	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.014	0.986	0.000
I15.1 Hypertension secondary to other renal disorders	0.014	0.986	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.014	0.986	0.000
E75.5 Other lipid storage disorders	0.013	0.986	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.013	0.987	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.013	0.987	0.000
E89.5 Postprocedural testicular hypofunction	0.013	0.987	0.000
E89.1 Postprocedural hypoinsulinaemia	0.013	0.987	0.000
E74 Other disorders of carbohydrate metabolism	0.013	0.987	0.000
I12.9 Hypertensive renal disease without renal failure	0.013	0.987	0.000
C80 Malignant neoplasm without specification of site	0.013	0.987	0.000
I11 Hypertensive heart disease	0.013	0.987	0.000
E88 Other metabolic disorders	0.013	0.987	0.000
E73.9 Lactose intolerance, unspecified	0.013	0.987	0.000
H73.8 Other specified disorders of tympanic membrane	0.000	0.987	0.013
I25.2 Old myocardial infarction	0.013	0.987	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.012	0.988	0.000
E75.6 Lipid storage disorder, unspecified	0.012	0.988	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.012	0.988	0.000
E75.3 Sphingolipidosis, unspecified	0.012	0.988	0.000
E75.2 Other sphingolipidosis	0.012	0.988	0.000
E75.1 Other gangliosidosis	0.012	0.988	0.000
E75.0 GM2 gangliosidosis	0.012	0.988	0.000
E73.8 Other lactose intolerance	0.012	0.988	0.000
E73.1 Secondary lactase deficiency	0.012	0.988	0.000
E73.0 Congenital lactase deficiency	0.012	0.988	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.012	0.988	0.000
E83.5 Disorders of calcium metabolism	0.012	0.988	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.012	0.988	0.000
E83.8 Other disorders of mineral metabolism	0.012	0.988	0.000
E83.2 Disorders of zinc metabolism	0.012	0.988	0.000
E83.0 Disorders of copper metabolism	0.012	0.988	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.988	0.012
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.011	0.988	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.011	0.988	0.000
E70.3 Albinism	0.011	0.988	0.000
E70.2 Disorders of tyrosine metabolism	0.011	0.988	0.000
E70.1 Other hyperphenylalaninaemias	0.011	0.988	0.000
E70.0 Classical phenylketonuria	0.011	0.988	0.000
E71.3 Disorders of fatty-acid metabolism	0.011	0.988	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.011	0.988	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.011	0.988	0.000
E71.0 Maple-syrup-urine disease	0.011	0.988	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.011	0.988	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.011	0.988	0.000
E72.5 Disorders of glycine metabolism	0.011	0.988	0.000
E72.4 Disorders of ornithine metabolism	0.011	0.988	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.011	0.988	0.000
E72.2 Disorders of urea cycle metabolism	0.011	0.988	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.011	0.988	0.000
E72.0 Disorders of amino-acid transport	0.011	0.988	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.011	0.988	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.011	0.988	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.011	0.988	0.000
E76.2 Other mucopolysaccharidoses	0.011	0.988	0.000
E76.1 Mucopolysaccharidosis, type II	0.011	0.988	0.000
E76.0 Mucopolysaccharidosis, type I	0.011	0.988	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.011	0.988	0.000
E77.8 Other disorders of glycoprotein metabolism	0.011	0.988	0.000
E77.1 Defects in glycoprotein degradation	0.011	0.988	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.011	0.988	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.011	0.988	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.011	0.988	0.000
E79.1 Lesch-Nyhan syndrome	0.011	0.988	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.011	0.988	0.000
E84.9 Cystic fibrosis, unspecified	0.011	0.988	0.000
E84.8 Cystic fibrosis with other manifestations	0.011	0.988	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.011	0.988	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.011	0.988	0.000
R91 Abnormal findings on diagnostic imaging of lung	0.000	0.988	0.012
E44 Protein-energy malnutrition of moderate and mild degree	0.011	0.989	0.000
E45 Retarded development following protein-energy malnutrition	0.011	0.989	0.000
E43 Unspecified severe protein-energy malnutrition	0.011	0.989	0.000
E42 Marasmic kwashiorkor	0.011	0.989	0.000
E41 Nutritional marasmus	0.011	0.989	0.000
E40 Kwashiorkor	0.011	0.989	0.000
I22.8 Subsequent myocardial infarction of other sites	0.011	0.989	0.000
E83.3 Disorders of phosphorus metabolism	0.011	0.989	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.010	0.990	0.000
E80.5 Crigler-Najjar syndrome	0.010	0.990	0.000
E80.3 Defects of catalase and peroxydase	0.010	0.990	0.000
E80.2 Other porphyria	0.010	0.990	0.000
E80.1 Porphyria cutanea tarda	0.010	0.990	0.000
E80.0 Hereditary erythropoietic porphyria	0.010	0.990	0.000
E50-E64 Other nutritional deficiencies	0.010	0.990	0.000
E88.9 Metabolic disorder, unspecified	0.010	0.990	0.000
E15 Nondiabetic hypoglycaemic coma	0.010	0.990	0.000
E88.8 Other specified metabolic disorders	0.010	0.990	0.000
E80.6 Other disorders of bilirubin metabolism	0.010	0.990	0.000
S01.0 Open wound of scalp	0.010	0.990	0.000
E46 Unspecified protein-energy malnutrition	0.010	0.990	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.010	0.990	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.010	0.990	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.010	0.990	0.000
E74.2 Disorders of galactose metabolism	0.010	0.990	0.000
E74.1 Disorders of fructose metabolism	0.010	0.990	0.000
E74.0 Glycogen storage disease	0.010	0.990	0.000
V23.4 Driver injured in traffic accident	0.010	0.990	0.000
E88.3 Tumour lysis syndrome	0.009	0.990	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.009	0.990	0.000
E85 Amyloidosis	0.009	0.990	0.000
F31 Bipolar affective disorder	0.000	0.991	0.009
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.991	0.009
H73 Other disorders of tympanic membrane	0.000	0.991	0.009
E80.4 Gilbert's syndrome	0.009	0.991	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.991	0.009
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.991	0.009
I22.1 Subsequent myocardial infarction of inferior wall	0.008	0.991	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.008	0.992	0.000
E44.1 Mild protein-energy malnutrition	0.008	0.992	0.000
E44.0 Moderate protein-energy malnutrition	0.008	0.992	0.000
E88.2 Lipomatosis, not elsewhere classified	0.008	0.992	0.000
E51 Thiamine deficiency	0.008	0.992	0.000
E16 Other disorders of pancreatic internal secretion	0.008	0.992	0.000
Chapter IX Diseases of the circulatory system	0.008	0.992	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.992	0.008
F31.9 Bipolar affective disorder, unspecified	0.000	0.992	0.008
E89.0 Postprocedural hypothyroidism	0.008	0.992	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.008	0.992	0.000
E63 Other nutritional deficiencies	0.008	0.992	0.000
E56 Other vitamin deficiencies	0.008	0.992	0.000
E50 Vitamin A deficiency	0.008	0.992	0.000
E60 Dietary zinc deficiency	0.008	0.992	0.000
E59 Dietary selenium deficiency	0.008	0.992	0.000
E58 Dietary calcium deficiency	0.008	0.992	0.000
E54 Ascorbic acid deficiency	0.008	0.992	0.000
E52 Niacin deficiency [pellagra]	0.008	0.992	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.992	0.008
S01.1 Open wound of eyelid and periocular area	0.008	0.992	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.007	0.993	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.993	0.007
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.993	0.007
S01.4 Open wound of cheek and temporomandibular area	0.007	0.993	0.000
S01 Open wound of head	0.007	0.993	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.007	0.993	0.000
E85.8 Other amyloidosis	0.007	0.993	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.007	0.993	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.007	0.993	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.007	0.993	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.993	0.007
E20-E35 Disorders of other endocrine glands	0.007	0.993	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.000	0.993	0.007
S01.5 Open wound of lip and oral cavity	0.007	0.993	0.000
H73.0 Acute myringitis	0.000	0.993	0.007
F31.8 Other bipolar affective disorders	0.000	0.993	0.007
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.993	0.007
I05-I09 Chronic rheumatic heart diseases	0.007	0.993	0.000
E83.4 Disorders of magnesium metabolism	0.007	0.993	0.000
I05.9 Mitral valve disease, unspecified	0.007	0.993	0.000
E51.2 Wernicke's encephalopathy	0.006	0.993	0.000
E61 Deficiency of other nutrient elements	0.006	0.994	0.000
E65-E68 Obesity and other hyperalimentation	0.006	0.994	0.000
I05 Rheumatic mitral valve diseases	0.006	0.994	0.000
H65-H75 Diseases of middle ear and mastoid	0.000	0.994	0.006
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.006	0.994	0.000
E85.3 Secondary systemic amyloidosis	0.006	0.994	0.000
E20 Hypoparathyroidism	0.006	0.994	0.000
E53 Deficiency of other B group vitamins	0.006	0.994	0.000
E16.1 Other hypoglycaemia	0.006	0.994	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.006	0.994	0.000
E51.9 Thiamine deficiency, unspecified	0.006	0.994	0.000
E51.8 Other manifestations of thiamine deficiency	0.006	0.994	0.000
E51.1 Beriberi	0.006	0.994	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.006	0.994	0.000
H73.1 Chronic myringitis	0.000	0.994	0.006
H74 Other disorders of middle ear and mastoid	0.000	0.994	0.006
E16.9 Disorder of pancreatic internal secretion, unspecified	0.006	0.994	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.006	0.994	0.000
E16.4 Abnormal secretion of gastrin	0.006	0.994	0.000
E16.3 Increased secretion of glucagon	0.006	0.994	0.000
I00-I02 Acute rheumatic fever	0.006	0.994	0.000
S01.7 Multiple open wounds of head	0.006	0.994	0.000
E20.9 Hypoparathyroidism, unspecified	0.006	0.994	0.000
E50.9 Vitamin A deficiency, unspecified	0.006	0.994	0.000
E50.8 Other manifestations of vitamin A deficiency	0.006	0.994	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.006	0.994	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.006	0.994	0.000
E50.5 Vitamin A deficiency with night blindness	0.006	0.994	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.006	0.994	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.006	0.994	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.006	0.994	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.006	0.994	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.006	0.994	0.000
E56.9 Vitamin deficiency, unspecified	0.006	0.994	0.000
E56.8 Deficiency of other vitamins	0.006	0.994	0.000
E56.1 Deficiency of vitamin K	0.006	0.994	0.000
E56.0 Deficiency of vitamin E	0.006	0.994	0.000
E63.9 Nutritional deficiency, unspecified	0.006	0.994	0.000
E63.8 Other specified nutritional deficiencies	0.006	0.994	0.000
E63.1 Imbalance of constituents of food intake	0.006	0.994	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.006	0.994	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.006	0.994	0.000
E64.8 Sequelae of other nutritional deficiencies	0.006	0.994	0.000
E64.3 Sequelae of rickets	0.006	0.994	0.000
E64.2 Sequelae of vitamin C deficiency	0.006	0.994	0.000
E64.1 Sequelae of vitamin A deficiency	0.006	0.994	0.000
E64.0 Sequelae of protein-energy malnutrition	0.006	0.994	0.000
N87.1 Moderate cervical dysplasia	0.000	0.994	0.006
S72.1 Pertrochanteric fracture	0.000	0.994	0.006
I07 Rheumatic tricuspid valve diseases	0.006	0.994	0.000
H66.9 Otitis media, unspecified	0.000	0.994	0.006
H71 Cholesteatoma of middle ear	0.000	0.994	0.006
E85.9 Amyloidosis, unspecified	0.005	0.994	0.000
E25 Adrenogenital disorders	0.005	0.994	0.000
E53.9 Vitamin B deficiency, unspecified	0.005	0.995	0.000
E85.4 Organ-limited amyloidosis	0.005	0.995	0.000
E34 Other endocrine disorders	0.005	0.995	0.000
E26 Hyperaldosteronism	0.005	0.995	0.000
H66 Suppurative and unspecified otitis media	0.000	0.995	0.005
I09 Other rheumatic heart diseases	0.005	0.995	0.000
I34.1 Mitral (valve) prolapse	0.000	0.995	0.005
E35 Disorders of endocrine glands in diseases classified elsewhere	0.005	0.995	0.000
E32 Diseases of thymus	0.005	0.995	0.000
E31 Polyglandular dysfunction	0.005	0.995	0.000
E30 Disorders of puberty, not elsewhere classified	0.005	0.995	0.000
I05.2 Mitral stenosis with insufficiency	0.005	0.995	0.000
E23 Hypofunction and other disorders of pituitary gland	0.005	0.995	0.000
E55 Vitamin D deficiency	0.005	0.995	0.000
E22 Hyperfunction of pituitary gland	0.005	0.995	0.000
I07.1 Tricuspid insufficiency	0.005	0.995	0.000
E24 Cushing's syndrome	0.005	0.995	0.000
E34.9 Endocrine disorder, unspecified	0.005	0.995	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.005	0.995	0.000
H74.0 Tympanosclerosis	0.000	0.995	0.005
F20.9 Schizophrenia, unspecified	0.005	0.995	0.000
H69 Other disorders of Eustachian tube	0.000	0.995	0.005
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.995	0.005
H74.1 Adhesive middle ear disease	0.000	0.995	0.005
I06 Rheumatic aortic valve diseases	0.005	0.995	0.000
E61.9 Deficiency of nutrient element, unspecified	0.005	0.995	0.000
E61.8 Deficiency of other specified nutrient elements	0.005	0.995	0.000
E61.7 Deficiency of multiple nutrient elements	0.005	0.995	0.000
E61.6 Vanadium deficiency	0.005	0.995	0.000
E61.5 Molybdenum deficiency	0.005	0.995	0.000
E61.4 Chromium deficiency	0.005	0.995	0.000
E61.3 Manganese deficiency	0.005	0.995	0.000
E61.0 Copper deficiency	0.005	0.995	0.000
I05.8 Other mitral valve diseases	0.005	0.995	0.000
E67 Other hyperalimentation	0.005	0.995	0.000
E68 Sequelae of hyperalimentation	0.005	0.995	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.995	0.005
I12.0 Hypertensive renal disease with renal failure	0.005	0.995	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.995	0.005
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.995	0.005
H68 Eustachian salpingitis and obstruction	0.000	0.995	0.005
H67 Otitis media in diseases classified elsewhere	0.000	0.995	0.005
E53.1 Pyridoxine deficiency	0.005	0.995	0.000
E53.0 Riboflavin deficiency	0.005	0.995	0.000
E20.8 Other hypoparathyroidism	0.005	0.995	0.000
E20.1 Pseudohypoparathyroidism	0.005	0.995	0.000
E20.0 Idiopathic hypoparathyroidism	0.005	0.995	0.000
E16.2 Hypoglycaemia, unspecified	0.005	0.995	0.000
J95.8 Other postprocedural respiratory disorders	0.000	0.995	0.005
E23.7 Disorder of pituitary gland, unspecified	0.005	0.995	0.000
I05.1 Rheumatic mitral insufficiency	0.005	0.995	0.000
V23.9 Unspecified motorcycle rider injured in traffic accident	0.004	0.995	0.000
V23.5 Passenger injured in traffic accident	0.004	0.995	0.000
V23.3 Person injured while boarding or alighting	0.004	0.995	0.000
V23.2 Unspecified motorcycle rider injured in nontraffic accident	0.004	0.995	0.000
V23.1 Passenger injured in nontraffic accident	0.004	0.995	0.000
V23.0 Driver injured in nontraffic accident	0.004	0.995	0.000
H74.4 Polyp of middle ear	0.000	0.995	0.005
H69.9 Eustachian tube disorder, unspecified	0.000	0.995	0.005
E61.2 Magnesium deficiency	0.004	0.995	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.004	0.995	0.000
I02 Rheumatic chorea	0.004	0.995	0.000
I01 Rheumatic fever with heart involvement	0.004	0.995	0.000
I00 Rheumatic fever without mention of heart involvement	0.004	0.995	0.000
E22.0 Acromegaly and pituitary gigantism	0.004	0.995	0.000
E00-E07 Disorders of thyroid gland	0.005	0.995	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.004	0.996	0.000
H70 Mastoiditis and related conditions	0.000	0.996	0.004
H92.1 Otorrhoea	0.000	0.996	0.004
S72.11 Pertrochanteric fracture (open)	0.000	0.996	0.004
I07.9 Tricuspid valve disease, unspecified	0.004	0.996	0.000
I07.8 Other tricuspid valve diseases	0.004	0.996	0.000
I07.2 Tricuspid stenosis with insufficiency	0.004	0.996	0.000
I07.0 Tricuspid stenosis	0.004	0.996	0.000
I09.9 Rheumatic heart disease, unspecified	0.004	0.996	0.000
E24.0 Pituitary-dependent Cushing's disease	0.004	0.996	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.004	0.996	0.000
E26.0 Primary hyperaldosteronism	0.004	0.996	0.000
E23.2 Diabetes insipidus	0.004	0.996	0.000
I05.0 Mitral stenosis	0.004	0.996	0.000
E25.9 Adrenogenital disorder, unspecified	0.004	0.996	0.000
E25.8 Other adrenogenital disorders	0.004	0.996	0.000
R61.9 Hyperhidrosis, unspecified	0.004	0.996	0.000
E26.9 Hyperaldosteronism, unspecified	0.004	0.996	0.000
E26.8 Other hyperaldosteronism	0.004	0.996	0.000
E26.1 Secondary hyperaldosteronism	0.004	0.996	0.000
E22.1 Hyperprolactinaemia	0.004	0.996	0.000
E34.5 Androgen resistance syndrome	0.004	0.996	0.000
E34.4 Constitutional tall stature	0.004	0.996	0.000
E34.3 Short stature, not elsewhere classified	0.004	0.996	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.004	0.996	0.000
E34.1 Other hypersecretion of intestinal hormones	0.004	0.996	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.996	0.004
E61.1 Iron deficiency	0.004	0.996	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.996	0.004
I09.8 Other specified rheumatic heart diseases	0.004	0.996	0.000
I09.2 Chronic rheumatic pericarditis	0.004	0.996	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.004	0.996	0.000
I09.0 Rheumatic myocarditis	0.004	0.996	0.000
S01.3 Open wound of ear	0.004	0.996	0.000
E29 Testicular dysfunction	0.004	0.996	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.004	0.996	0.000
E23.1 Drug-induced hypopituitarism	0.004	0.996	0.000
E24.2 Drug-induced Cushing's syndrome	0.004	0.996	0.000
E30.9 Disorder of puberty, unspecified	0.004	0.996	0.000
E30.8 Other disorders of puberty	0.004	0.996	0.000
E30.1 Precocious puberty	0.004	0.996	0.000
E30.0 Delayed puberty	0.004	0.996	0.000
E31.9 Polyglandular dysfunction, unspecified	0.004	0.996	0.000
E31.8 Other polyglandular dysfunction	0.004	0.996	0.000
E31.1 Polyglandular hyperfunction	0.004	0.996	0.000
E31.0 Autoimmune polyglandular failure	0.004	0.996	0.000
E32.9 Disease of thymus, unspecified	0.004	0.996	0.000
E32.8 Other diseases of thymus	0.004	0.996	0.000
E32.1 Abscess of thymus	0.004	0.996	0.000
E32.0 Persistent hyperplasia of thymus	0.004	0.996	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.004	0.996	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.004	0.996	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.004	0.996	0.000
E55.0 Rickets, active	0.004	0.996	0.000
E23.6 Other disorders of pituitary gland	0.004	0.996	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.004	0.996	0.000
E22.8 Other hyperfunction of pituitary gland	0.004	0.996	0.000
E24.8 Other Cushing's syndrome	0.004	0.996	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.004	0.996	0.000
E24.3 Ectopic ACTH syndrome	0.004	0.996	0.000
E24.1 Nelson's syndrome	0.004	0.996	0.000
H72 Perforation of tympanic membrane	0.000	0.996	0.004
H69.0 Patulous Eustachian tube	0.000	0.996	0.004
I06.9 Rheumatic aortic valve disease, unspecified	0.004	0.996	0.000
I06.8 Other rheumatic aortic valve diseases	0.004	0.996	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.004	0.996	0.000
I06.1 Rheumatic aortic insufficiency	0.004	0.996	0.000
E67.8 Other specified hyperalimentation	0.004	0.996	0.000
E67.3 Hypervitaminosis D	0.004	0.996	0.000
E67.2 Megavitamin-B6 syndrome	0.004	0.996	0.000
E67.1 Hypercarotenaemia	0.004	0.996	0.000
E67.0 Hypervitaminosis A	0.004	0.996	0.000
S92.40 Fracture of great toe (closed)	0.004	0.996	0.000
B37.8 Candidiasis of other sites	0.000	0.996	0.004
H66.0 Acute suppurative otitis media	0.000	0.996	0.004
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.996	0.004
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.996	0.004
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.996	0.004
H68.1 Obstruction of Eustachian tube	0.000	0.996	0.004
H68.0 Eustachian salpingitis	0.000	0.996	0.004
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.996	0.004
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.996	0.004
E34.8 Other specified endocrine disorders	0.004	0.996	0.000
I06.0 Rheumatic aortic stenosis	0.004	0.996	0.000
H66.4 Suppurative otitis media, unspecified	0.000	0.996	0.004

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations