TreeWAS – Variant ID: rs9818870

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I20-I25 Ischaemic heart diseases	1.000	0.000	0.000
I25 Chronic ischaemic heart disease	1.000	0.000	0.000
I25.1 Atherosclerotic heart disease	0.999	0.001	0.000
I20 Angina pectoris	0.999	0.001	0.000
I20.0 Unstable angina	0.998	0.002	0.000
I10 Essential (primary) hypertension	0.997	0.003	0.000
I10-I15 Hypertensive diseases	0.996	0.004	0.000
Chapter IX Diseases of the circulatory system	0.995	0.005	0.000
I22 Subsequent myocardial infarction	0.979	0.021	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.976	0.024	0.000
I70 Atherosclerosis	0.938	0.062	0.000
I72 Other aneurysm	0.934	0.066	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.928	0.072	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.911	0.089	0.000
I20.1 Angina pectoris with documented spasm	0.906	0.094	0.000
I72.8 Aneurysm of other specified arteries	0.890	0.110	0.000
I25.2 Old myocardial infarction	0.863	0.137	0.000
I11 Hypertensive heart disease	0.859	0.141	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.856	0.144	0.000
I60-I69 Cerebrovascular diseases	0.851	0.149	0.000
I69 Sequelae of cerebrovascular disease	0.849	0.151	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.846	0.154	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.843	0.157	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.834	0.166	0.000
I69.3 Sequelae of cerebral infarction	0.830	0.170	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.826	0.174	0.000
I77 Other disorders of arteries and arterioles	0.824	0.176	0.000
I21 Acute myocardial infarction	0.801	0.199	0.000
I72.4 Aneurysm of artery of lower extremity	0.774	0.226	0.000
I22.8 Subsequent myocardial infarction of other sites	0.772	0.228	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.752	0.247	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.731	0.269	0.000
I25.3 Aneurysm of heart	0.729	0.271	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.727	0.272	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.727	0.273	0.000
I00-I02 Acute rheumatic fever	0.727	0.273	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.720	0.280	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.719	0.281	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.719	0.281	0.000
I25.6 Silent myocardial ischaemia	0.717	0.283	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.716	0.284	0.000
I13 Hypertensive heart and renal disease	0.714	0.286	0.000
I21.9 Acute myocardial infarction, unspecified	0.712	0.288	0.000
I70.0 Atherosclerosis of aorta	0.712	0.288	0.000
I70.8 Atherosclerosis of other arteries	0.711	0.289	0.000
I72.2 Aneurysm of renal artery	0.709	0.291	0.000
I77.1 Stricture of artery	0.700	0.300	0.000
I15 Secondary hypertension	0.692	0.308	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.691	0.309	0.000
I72.3 Aneurysm of iliac artery	0.691	0.309	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.689	0.311	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.688	0.312	0.000
I24 Other acute ischaemic heart diseases	0.674	0.326	0.000
I70.9 Generalised and unspecified atherosclerosis	0.672	0.327	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.670	0.330	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.670	0.330	0.000
I72.1 Aneurysm of artery of upper extremity	0.670	0.330	0.000
I77.8 Other specified disorders of arteries and arterioles	0.664	0.336	0.000
I25.5 Ischaemic cardiomyopathy	0.662	0.338	0.000
I73 Other peripheral vascular diseases	0.658	0.342	0.000
I72.9 Aneurysm of unspecified site	0.657	0.343	0.000
I62 Other nontraumatic intracranial haemorrhage	0.648	0.352	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.648	0.352	0.000
I20.9 Angina pectoris, unspecified	0.644	0.356	0.000
I23 Certain current complications following acute myocardial infarction	0.631	0.369	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.631	0.369	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.620	0.380	0.000
I78 Diseases of capillaries	0.618	0.382	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.602	0.398	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.600	0.400	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.592	0.407	0.000
I79.1 Aortitis in diseases classified elsewhere	0.592	0.407	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.592	0.407	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.591	0.408	0.000
I77.5 Necrosis of artery	0.590	0.409	0.000
I77.4 Coeliac artery compression syndrome	0.590	0.409	0.000
I77.3 Arterial fibromuscular dysplasia	0.590	0.409	0.000
I77.2 Rupture of artery	0.590	0.409	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.587	0.413	0.000
I24.8 Other forms of acute ischaemic heart disease	0.586	0.414	0.000
I20.8 Other forms of angina pectoris	0.585	0.415	0.000
I61 Intracerebral haemorrhage	0.583	0.417	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.574	0.426	0.000
I77.6 Arteritis, unspecified	0.573	0.427	0.000
I70.1 Atherosclerosis of renal artery	0.571	0.429	0.000
I72.0 Aneurysm of carotid artery	0.570	0.430	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.562	0.438	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.561	0.439	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.549	0.451	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.548	0.452	0.000
I73.0 Raynaud's syndrome	0.546	0.454	0.000
I00 Rheumatic fever without mention of heart involvement	0.535	0.465	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.530	0.470	0.000
I77.0 Arteriovenous fistula, acquired	0.528	0.472	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.524	0.476	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.522	0.478	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.522	0.478	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.522	0.478	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.522	0.478	0.000
I02 Rheumatic chorea	0.521	0.478	0.000
I01 Rheumatic fever with heart involvement	0.521	0.478	0.000
I15.0 Renovascular hypertension	0.521	0.479	0.000
I12 Hypertensive renal disease	0.519	0.481	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.512	0.488	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.512	0.488	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.512	0.488	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.512	0.488	0.000
I28 Other diseases of pulmonary vessels	0.511	0.489	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.510	0.490	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.510	0.490	0.000
I25.4 Coronary artery aneurysm	0.498	0.502	0.001
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.497	0.503	0.000
I15.8 Other secondary hypertension	0.496	0.504	0.000
I15.2 Hypertension secondary to endocrine disorders	0.496	0.504	0.000
I73.8 Other specified peripheral vascular diseases	0.494	0.506	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.482	0.518	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.482	0.518	0.000
I63 Cerebral infarction	0.480	0.520	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.476	0.524	0.000
I15.1 Hypertension secondary to other renal disorders	0.475	0.525	0.000
E78.0 Pure hypercholesterolaemia	0.475	0.525	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.473	0.527	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.473	0.527	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.473	0.527	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.472	0.528	0.000
I15.9 Seconday hypertension, unspecified	0.466	0.534	0.000
I62.1 Nontraumatic extradural haemorrhage	0.465	0.535	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.460	0.540	0.000
I24.1 Dressler's syndrome	0.455	0.545	0.000
I68.0 Cerebral amyloid angiopathy	0.455	0.545	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.452	0.547	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.452	0.547	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.452	0.547	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.452	0.547	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.452	0.547	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.452	0.547	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.452	0.547	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.450	0.550	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.449	0.551	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.445	0.555	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.445	0.555	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.445	0.555	0.000
I78.9 Disease of capillaries, unspecified	0.443	0.557	0.000
I61.8 Other intracerebral haemorrhage	0.441	0.559	0.000
I27 Other pulmonary heart diseases	0.423	0.577	0.000
I28.8 Other specified diseases of pulmonary vessels	0.413	0.586	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.409	0.590	0.000
I78.8 Other diseases of capillaries	0.403	0.596	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.395	0.605	0.000
I12.9 Hypertensive renal disease without renal failure	0.387	0.612	0.000
I99 Other and unspecified disorders of circulatory system	0.387	0.613	0.000
I74 Arterial embolism and thrombosis	0.387	0.613	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.381	0.619	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.376	0.624	0.000
I26 Pulmonary embolism	0.375	0.625	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.374	0.626	0.000
I01.8 Other acute rheumatic heart disease	0.374	0.626	0.000
I01.2 Acute rheumatic myocarditis	0.374	0.626	0.000
I01.1 Acute rheumatic endocarditis	0.374	0.626	0.000
I01.0 Acute rheumatic pericarditis	0.374	0.626	0.000
I02.9 Rheumatic chorea without heart involvement	0.374	0.626	0.000
I02.0 Rheumatic chorea with heart involvement	0.374	0.626	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.369	0.630	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.368	0.631	0.000
I23.8 Other current complications following acute myocardial infarction	0.366	0.633	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.367	0.633	0.000
I28.1 Aneurysm of pulmonary artery	0.367	0.633	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.367	0.633	0.000
I63.9 Cerebral infarction, unspecified	0.364	0.636	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.356	0.644	0.000
I27.9 Pulmonary heart disease, unspecified	0.356	0.644	0.000
I21.4 Acute subendocardial myocardial infarction	0.355	0.645	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.351	0.649	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.346	0.654	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.344	0.656	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.344	0.656	0.000
I63.8 Other cerebral infarction	0.337	0.663	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.332	0.668	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.324	0.676	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.322	0.678	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.322	0.678	0.000
I65.1 Occlusion and stenosis of basilar artery	0.322	0.678	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.320	0.680	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.307	0.692	0.001
I27.1 Kyphoscoliotic heart disease	0.303	0.696	0.000
I27.8 Other specified pulmonary heart diseases	0.303	0.697	0.000
I71 Aortic aneurysm and dissection	0.298	0.702	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.291	0.709	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.290	0.710	0.000
I74.5 Embolism and thrombosis of iliac artery	0.287	0.713	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.282	0.718	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.280	0.720	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.278	0.722	0.000
I74.8 Embolism and thrombosis of other arteries	0.275	0.725	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.270	0.730	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.264	0.736	0.000
I97.2 Postmastectomy lymphoedema syndrome	0.259	0.740	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.256	0.743	0.001
I27.0 Primary pulmonary hypertension	0.256	0.744	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.244	0.755	0.000
I97.9 Postprocedural disorder of circulatory system, unspecified	0.238	0.762	0.000
I97.0 Postcardiotomy syndrome	0.238	0.762	0.000
I73.9 Peripheral vascular disease, unspecified	0.234	0.766	0.000
I78.1 Naevus, nonneoplastic	0.228	0.772	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.223	0.777	0.000
I65.2 Occlusion and stenosis of carotid artery	0.222	0.778	0.000
I27.2 Other secondary pulmonary hypertension	0.218	0.782	0.000
I97.1 Other functional disturbances following cardiac surgery	0.218	0.782	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.218	0.782	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.215	0.785	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.215	0.785	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.214	0.786	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.214	0.786	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.214	0.786	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.214	0.786	0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.202	0.798	0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.202	0.798	0.000
I98.0 Cardiovascular syphilis	0.202	0.798	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.196	0.804	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.186	0.814	0.000
I05-I09 Chronic rheumatic heart diseases	0.175	0.825	0.001
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.167	0.833	0.000
I71.0 Dissection of aorta [any part]	0.166	0.834	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.165	0.835	0.000
I60 Subarachnoid haemorrhage	0.164	0.836	0.001
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.154	0.845	0.001
I98.2 Oesophageal varices in diseases classified elsewhere	0.155	0.845	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.144	0.856	0.000
I12.0 Hypertensive renal disease with renal failure	0.139	0.861	0.000
I06 Rheumatic aortic valve diseases	0.133	0.867	0.001
I60.8 Other subarachnoid haemorrhage	0.123	0.877	0.001
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.122	0.878	0.001
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.117	0.882	0.001
I60.5 Subarachnoid haemorrhage from vertebral artery	0.117	0.882	0.001
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.117	0.882	0.001
I09 Other rheumatic heart diseases	0.117	0.882	0.001
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.110	0.889	0.001
I07 Rheumatic tricuspid valve diseases	0.109	0.891	0.001
I60.4 Subarachnoid haemorrhage from basilar artery	0.107	0.892	0.001
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.106	0.894	0.000
I06.1 Rheumatic aortic insufficiency	0.102	0.897	0.001
I06.9 Rheumatic aortic valve disease, unspecified	0.095	0.904	0.001
I06.8 Other rheumatic aortic valve diseases	0.095	0.904	0.001
I06.2 Rheumatic aortic stenosis with insufficiency	0.095	0.904	0.001
I06.0 Rheumatic aortic stenosis	0.095	0.904	0.001
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.095	0.904	0.001
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.091	0.908	0.001
E78.4 Other hyperlipidaemia	0.091	0.909	0.000
I95 Hypotension	0.087	0.913	0.000
E78.6 Lipoprotein deficiency	0.085	0.914	0.000
I09.8 Other specified rheumatic heart diseases	0.084	0.915	0.001
I09.2 Chronic rheumatic pericarditis	0.084	0.915	0.001
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.084	0.915	0.001
I09.0 Rheumatic myocarditis	0.084	0.915	0.001
I07.9 Tricuspid valve disease, unspecified	0.078	0.921	0.001
I07.8 Other tricuspid valve diseases	0.078	0.921	0.001
I07.2 Tricuspid stenosis with insufficiency	0.078	0.921	0.001
I07.0 Tricuspid stenosis	0.078	0.921	0.001
E78.3 Hyperchylomicronaemia	0.076	0.924	0.000
I09.9 Rheumatic heart disease, unspecified	0.075	0.924	0.001
I67 Other cerebrovascular diseases	0.073	0.926	0.000
I95.8 Other hypotension	0.070	0.930	0.000
E70-E90 Metabolic disorders	0.069	0.931	0.000
E78.2 Mixed hyperlipidaemia	0.069	0.931	0.000
E85 Amyloidosis	0.065	0.935	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.061	0.937	0.001
I07.1 Tricuspid insufficiency	0.062	0.938	0.000
E73 Lactose intolerance	0.062	0.938	0.000
E78.8 Other disorders of lipoprotein metabolism	0.061	0.939	0.000
E85.9 Amyloidosis, unspecified	0.059	0.941	0.000
Z95.1 Presence of aortocoronary bypass graft	0.059	0.941	0.000
I95.0 Idiopathic hypotension	0.058	0.942	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.057	0.943	0.000
E73.9 Lactose intolerance, unspecified	0.057	0.943	0.000
E88 Other metabolic disorders	0.056	0.944	0.000
E85.3 Secondary systemic amyloidosis	0.055	0.945	0.000
I95.2 Hypotension due to drugs	0.054	0.946	0.000
E84 Cystic fibrosis	0.054	0.946	0.000
E78.1 Pure hyperglyceridaemia	0.053	0.946	0.000
E74 Other disorders of carbohydrate metabolism	0.053	0.947	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.053	0.947	0.000
I67.5 Moyamoya disease	0.053	0.947	0.000
I67.4 Hypertensive encephalopathy	0.053	0.947	0.000
I67.3 Progressive vascular leukoencephalopathy	0.053	0.947	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.051	0.949	0.000
E79 Disorders of purine and pyrimidine metabolism	0.050	0.950	0.000
E77 Disorders of glycoprotein metabolism	0.050	0.950	0.000
E76 Disorders of glycosaminoglycan metabolism	0.050	0.950	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.050	0.950	0.000
E72 Other disorders of amino-acid metabolism	0.050	0.950	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.050	0.950	0.000
E70 Disorders of aromatic amino-acid metabolism	0.050	0.950	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.050	0.950	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.050	0.950	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.047	0.953	0.000
E85.8 Other amyloidosis	0.046	0.953	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.046	0.953	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.046	0.953	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.046	0.953	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.046	0.954	0.000
E83 Disorders of mineral metabolism	0.046	0.954	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.045	0.955	0.000
E73.8 Other lactose intolerance	0.044	0.955	0.000
E73.1 Secondary lactase deficiency	0.044	0.955	0.000
E73.0 Congenital lactase deficiency	0.044	0.955	0.000
E85.4 Organ-limited amyloidosis	0.044	0.956	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.044	0.956	0.000
E11.9 Without complications	0.043	0.957	0.000
E84.9 Cystic fibrosis, unspecified	0.042	0.957	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.042	0.958	0.000
E83.1 Disorders of iron metabolism	0.041	0.959	0.000
E88.9 Metabolic disorder, unspecified	0.041	0.959	0.000
E88.8 Other specified metabolic disorders	0.041	0.959	0.000
E88.3 Tumour lysis syndrome	0.041	0.959	0.000
I05 Rheumatic mitral valve diseases	0.039	0.959	0.002
E87.2 Acidosis	0.040	0.960	0.000
E84.8 Cystic fibrosis with other manifestations	0.039	0.961	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.039	0.961	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.039	0.961	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.038	0.962	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.038	0.962	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.038	0.962	0.000
E74.2 Disorders of galactose metabolism	0.038	0.962	0.000
E74.1 Disorders of fructose metabolism	0.038	0.962	0.000
E74.0 Glycogen storage disease	0.038	0.962	0.000
E88.2 Lipomatosis, not elsewhere classified	0.038	0.962	0.000
E87.3 Alkalosis	0.037	0.963	0.000
E80.6 Other disorders of bilirubin metabolism	0.037	0.963	0.000
E87.0 Hyperosmolality and hypernatraemia	0.037	0.963	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.036	0.964	0.000
I67.2 Cerebral atherosclerosis	0.036	0.964	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.036	0.964	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.036	0.964	0.000
E70.3 Albinism	0.036	0.964	0.000
E70.2 Disorders of tyrosine metabolism	0.036	0.964	0.000
E70.1 Other hyperphenylalaninaemias	0.036	0.964	0.000
E70.0 Classical phenylketonuria	0.036	0.964	0.000
E71.3 Disorders of fatty-acid metabolism	0.036	0.964	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.036	0.964	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.036	0.964	0.000
E71.0 Maple-syrup-urine disease	0.036	0.964	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.036	0.964	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.036	0.964	0.000
E72.5 Disorders of glycine metabolism	0.036	0.964	0.000
E72.4 Disorders of ornithine metabolism	0.036	0.964	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.036	0.964	0.000
E72.2 Disorders of urea cycle metabolism	0.036	0.964	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.036	0.964	0.000
E72.0 Disorders of amino-acid transport	0.036	0.964	0.000
E75.6 Lipid storage disorder, unspecified	0.036	0.964	0.000
E75.5 Other lipid storage disorders	0.036	0.964	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.036	0.964	0.000
E75.3 Sphingolipidosis, unspecified	0.036	0.964	0.000
E75.2 Other sphingolipidosis	0.036	0.964	0.000
E75.1 Other gangliosidosis	0.036	0.964	0.000
E75.0 GM2 gangliosidosis	0.036	0.964	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.036	0.964	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.036	0.964	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.036	0.964	0.000
E76.2 Other mucopolysaccharidoses	0.036	0.964	0.000
E76.1 Mucopolysaccharidosis, type II	0.036	0.964	0.000
E76.0 Mucopolysaccharidosis, type I	0.036	0.964	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.036	0.964	0.000
E77.8 Other disorders of glycoprotein metabolism	0.036	0.964	0.000
E77.1 Defects in glycoprotein degradation	0.036	0.964	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.036	0.964	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.036	0.964	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.036	0.964	0.000
E79.1 Lesch-Nyhan syndrome	0.036	0.964	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.036	0.964	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.035	0.965	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.032	0.967	0.001
E87.4 Mixed disorder of acid-base balance	0.033	0.967	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.033	0.967	0.000
E83.8 Other disorders of mineral metabolism	0.033	0.967	0.000
E83.2 Disorders of zinc metabolism	0.033	0.967	0.000
E83.0 Disorders of copper metabolism	0.033	0.967	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.032	0.967	0.000
E80.5 Crigler-Najjar syndrome	0.032	0.967	0.000
E80.3 Defects of catalase and peroxydase	0.032	0.967	0.000
E80.2 Other porphyria	0.032	0.967	0.000
E80.1 Porphyria cutanea tarda	0.032	0.967	0.000
E80.0 Hereditary erythropoietic porphyria	0.032	0.967	0.000
E83.4 Disorders of magnesium metabolism	0.032	0.968	0.000
E87.6 Hypokalaemia	0.032	0.968	0.000
E87.5 Hyperkalaemia	0.032	0.968	0.000
I05.8 Other mitral valve diseases	0.028	0.971	0.001
I67.9 Cerebrovascular disease, unspecified	0.029	0.971	0.000
E89.3 Postprocedural hypopituitarism	0.028	0.972	0.000
E89.2 Postprocedural hypoparathyroidism	0.027	0.973	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.026	0.974	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.026	0.974	0.000
E89.5 Postprocedural testicular hypofunction	0.026	0.974	0.000
E89.4 Postprocedural ovarian failure	0.026	0.974	0.000
E89.1 Postprocedural hypoinsulinaemia	0.026	0.974	0.000
I05.0 Mitral stenosis	0.025	0.974	0.001
E83.3 Disorders of phosphorus metabolism	0.026	0.974	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.026	0.974	0.000
I67.1 Cerebral aneurysm, nonruptured	0.023	0.977	0.000
I05.1 Rheumatic mitral insufficiency	0.020	0.978	0.002
I05.9 Mitral valve disease, unspecified	0.018	0.980	0.001
E80.4 Gilbert's syndrome	0.019	0.981	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.018	0.982	0.000
I95.1 Orthostatic hypotension	0.018	0.982	0.000
I05.2 Mitral stenosis with insufficiency	0.015	0.983	0.002
E83.5 Disorders of calcium metabolism	0.017	0.983	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.016	0.984	0.000
V10-V19 Pedal cyclist injured in transport accident	0.015	0.985	0.000
V19 Pedal cyclist injured in other and unspecified transport accidents	0.015	0.985	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.015	0.985	0.000
I08 Multiple valve diseases	0.014	0.985	0.001
V19.3 Pedal cyclist [any] injured in an unspecified nontraffic accident	0.015	0.985	0.000
E87.7 Fluid overload	0.014	0.986	0.000
V18.0 Driver injured in nontraffic accident	0.014	0.986	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.014	0.986	0.000
Chapter XX External causes of morbidity and mortality	0.013	0.987	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.013	0.987	0.000
Y52 Agents primarily affecting the cardiovascular system	0.013	0.987	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.013	0.987	0.000
C85.1 B-cell lymphoma, unspecified	0.000	0.987	0.013
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.987	0.013
V18.3 Person injured while boarding or alighting	0.012	0.987	0.000
Y95 Nosocomial condition	0.013	0.987	0.000
E86 Volume depletion	0.012	0.988	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.012	0.988	0.000
W00-W19 Falls	0.012	0.988	0.000
W50-W64 Exposure to animate mechanical forces	0.012	0.988	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.988	0.012
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.012	0.988	0.000
V19.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.012	0.988	0.000
Y59 Other and unspecified vaccines and biological substances	0.012	0.988	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.012	0.988	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.012	0.988	0.000
V18.9 Unspecified pedal cyclist injured in traffic accident	0.011	0.988	0.000
V18.4 Driver injured in traffic accident	0.011	0.988	0.000
V18.5 Passenger injured in traffic accident	0.011	0.988	0.000
V18.1 Passenger injured in nontraffic accident	0.011	0.988	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.011	0.989	0.000
V19.8 Pedal cyclist [any] injured in other specified transport accidents	0.011	0.989	0.000
Y45.8 Other analgesics and antipyretics	0.011	0.989	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.011	0.989	0.000
V16 Pedal cyclist injured in collision with other nonmotor vehicle	0.011	0.989	0.000
V15 Pedal cyclist injured in collision with railway train or railway vehicle	0.011	0.989	0.000
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus	0.011	0.989	0.000
V13 Pedal cyclist injured in collision with car, pick-up truck or van	0.011	0.989	0.000
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle	0.011	0.989	0.000
V10 Pedal cyclist injured in collision with pedestrian or animal	0.011	0.989	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.011	0.989	0.000
Y45.2 Propionic acid derivatives	0.011	0.989	0.000
V19.9 Pedal cyclist [any] injured in unspecified traffic accident	0.011	0.989	0.000
V19.6 Unspecified pedal cyclist injured in collision with other and unspecified motor vehicles in traffic accident	0.011	0.989	0.000
V19.2 Unspecified pedal cyclist injured in collision with other and unspecified motor vehicles in nontraffic accident	0.011	0.989	0.000
V19.5 Passenger injured in collision with other and unspecified motor vehicles in traffic accident	0.011	0.989	0.000
V19.1 Passenger injured in collision with other and unspecified motor vehicles in nontraffic accident	0.011	0.989	0.000
V19.0 Driver injured in collision with other and unspecified motor vehicles in nontraffic accident	0.011	0.989	0.000
C91 Lymphoid leukaemia	0.000	0.989	0.011
K50.9 Crohn's disease, unspecified	0.011	0.989	0.000
Y54.4 Loop [high-ceiling] diuretics	0.011	0.989	0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.011	0.989	0.000
X60-X84 Intentional self-harm	0.011	0.989	0.000
Z86.7 Personal history of diseases of the circulatory system	0.011	0.989	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.011	0.989	0.000
I08.9 Multiple valve disease, unspecified	0.010	0.989	0.001
W60 Contact with plant thorns and spines and sharp leaves	0.011	0.989	0.000
V11 Pedal cyclist injured in collision with other pedal cycle	0.010	0.989	0.000
C91.1 Chronic lymphocytic leukaemia	0.000	0.989	0.011
Y52.3 Coronary vasodilators, not elsewhere classified	0.011	0.989	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.011	0.989	0.000
Y45.5 4-Aminophenol derivatives	0.010	0.989	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.010	0.989	0.000
W05 Fall involving wheelchair	0.010	0.990	0.000
W75-W84 Other accidental threats to breathing	0.010	0.990	0.000
W17 Other fall from one level to another	0.010	0.990	0.000
Y54.8 Agents affecting uric acid metabolism	0.010	0.990	0.000
W06 Fall involving bed	0.010	0.990	0.000
Y00-Y09 Assault	0.010	0.990	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.990	0.010
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.010	0.990	0.000
W10 Fall on and from stairs and steps	0.010	0.990	0.000
V90-V94 Water transport accidents	0.010	0.990	0.000
V17 Pedal cyclist injured in collision with fixed or stationary object	0.010	0.990	0.000
V70-V79 Bus occupant injured in transport accident	0.010	0.990	0.000
Y56.3 Emollients, demulcents and protectants	0.010	0.990	0.000
Y58 Bacterial vaccines	0.010	0.990	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.010	0.990	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.010	0.990	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.010	0.990	0.000
C91.0 Acute lymphoblastic leukaemia	0.000	0.990	0.010
W57.0 Home	0.010	0.990	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.990	0.010
W11 Fall on and from ladder	0.010	0.990	0.000
Y59.0 Viral vaccines	0.010	0.990	0.000
I67.8 Other specified cerebrovascular diseases	0.010	0.990	0.000
X00-X09 Exposure to smoke, fire and flames	0.010	0.990	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.010	0.990	0.000
W13 Fall from, out of or through building or structure	0.010	0.990	0.000
V98-V99 Other and unspecified transport accidents	0.010	0.990	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.010	0.990	0.000
Y10-Y34 Event of undetermined intent	0.010	0.990	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.990	0.010

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations