TreeWAS – Variant ID: rs987237

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E11.9 Without complications	0.999	0.001	0.000
E11 Non-insulin-dependent diabetes mellitus	0.989	0.011	0.000
E10-E14 Diabetes mellitus	0.987	0.013	0.000
E66.9 Obesity, unspecified	0.972	0.028	0.000
E66 Obesity	0.968	0.032	0.000
E65-E68 Obesity and other hyperalimentation	0.964	0.036	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.959	0.041	0.000
E10 Insulin-dependent diabetes mellitus	0.949	0.051	0.000
E14 Unspecified diabetes mellitus	0.921	0.079	0.000
E10.3 With ophthalmic complications	0.911	0.089	0.000
E10.9 Without complications	0.900	0.100	0.000
E66.0 Obesity due to excess calories	0.865	0.135	0.000
E14.3 With ophthalmic complications	0.833	0.167	0.000
E65 Localised adiposity	0.823	0.177	0.000
E11.6 With other specified complications	0.810	0.190	0.000
E10.5 With peripheral circulatory complications	0.809	0.191	0.000
E11.1 With ketoacidosis	0.763	0.237	0.000
E11.2 With renal complications	0.759	0.241	0.000
E14.9 Without complications	0.749	0.251	0.000
E50-E64 Other nutritional deficiencies	0.720	0.280	0.000
E11.7 With multiple complications	0.709	0.291	0.000
E12 Malnutrition-related diabetes mellitus	0.708	0.292	0.000
E66.1 Drug-induced obesity	0.694	0.306	0.000
E11.8 With unspecified complications	0.694	0.306	0.000
E67 Other hyperalimentation	0.691	0.309	0.000
E68 Sequelae of hyperalimentation	0.691	0.309	0.000
I10 Essential (primary) hypertension	0.691	0.309	0.000
E14.2 Withrenal complications	0.684	0.315	0.000
E14.1 With ketoacidosis	0.684	0.316	0.000
E14.4 With neurological complications	0.682	0.318	0.000
E20-E35 Disorders of other endocrine glands	0.682	0.318	0.000
E10.7 With multiple complications	0.680	0.320	0.000
E10.6 With other specified complications	0.679	0.321	0.000
E11.4 With neurological complications	0.677	0.323	0.000
E14.6 With other specified complications	0.676	0.324	0.000
E10.2 With renal complications	0.674	0.326	0.000
E14.5 With peripheral circulatory complications	0.663	0.337	0.000
E14.7 With multiple complications	0.660	0.339	0.000
E14.0 With coma	0.660	0.339	0.000
E28 Ovarian dysfunction	0.658	0.342	0.000
E10.0 With coma	0.645	0.355	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.641	0.359	0.000
E40-E46 Malnutrition	0.637	0.363	0.000
E14.8 With unspecified complications	0.620	0.380	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.612	0.388	0.000
E28.3 Primary ovarian failure	0.606	0.394	0.000
E28.2 Polycystic ovarian syndrome	0.595	0.405	0.000
E13 Other specified diabetes mellitus	0.586	0.414	0.000
E26 Hyperaldosteronism	0.574	0.426	0.000
E58 Dietary calcium deficiency	0.560	0.439	0.000
E10.8 With unspecified complications	0.553	0.447	0.000
E24 Cushing's syndrome	0.540	0.460	0.000
E53 Deficiency of other B group vitamins	0.529	0.471	0.000
E66.8 Other obesity	0.518	0.482	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.516	0.484	0.000
E63 Other nutritional deficiencies	0.516	0.484	0.000
E56 Other vitamin deficiencies	0.516	0.484	0.000
E51 Thiamine deficiency	0.516	0.484	0.000
E50 Vitamin A deficiency	0.516	0.484	0.000
E60 Dietary zinc deficiency	0.516	0.484	0.000
E59 Dietary selenium deficiency	0.516	0.484	0.000
E54 Ascorbic acid deficiency	0.516	0.484	0.000
E52 Niacin deficiency [pellagra]	0.516	0.484	0.000
E61 Deficiency of other nutrient elements	0.512	0.488	0.000
E12.9 Without complications	0.507	0.492	0.000
E12.8 With unspecified complications	0.507	0.492	0.000
E12.7 With multiple complications	0.507	0.492	0.000
E12.6 With other specified complications	0.507	0.492	0.000
E12.5 With peripheral circulatory complications	0.507	0.492	0.000
E12.4 With neurological complications	0.507	0.492	0.000
E12.3 With ophthalmic complications	0.507	0.492	0.000
E12.2 With renal complications	0.507	0.492	0.000
E12.1 With ketoacidosis	0.507	0.492	0.000
E12.0 With coma	0.507	0.492	0.000
E67.8 Other specified hyperalimentation	0.496	0.504	0.000
E67.3 Hypervitaminosis D	0.496	0.504	0.000
E67.2 Megavitamin-B6 syndrome	0.496	0.504	0.000
E67.1 Hypercarotenaemia	0.496	0.504	0.000
E67.0 Hypervitaminosis A	0.496	0.504	0.000
E11.3 With ophthalmic complications	0.494	0.506	0.000
E22 Hyperfunction of pituitary gland	0.491	0.509	0.000
E55 Vitamin D deficiency	0.490	0.510	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.489	0.511	0.000
E32 Diseases of thymus	0.489	0.511	0.000
E31 Polyglandular dysfunction	0.489	0.511	0.000
E30 Disorders of puberty, not elsewhere classified	0.489	0.511	0.000
E25 Adrenogenital disorders	0.489	0.511	0.000
E28.9 Ovarian dysfunction, unspecified	0.472	0.528	0.000
E28.8 Other ovarian dysfunction	0.472	0.528	0.000
E28.1 Androgen excess	0.472	0.528	0.000
E28.0 Oestrogen excess	0.472	0.528	0.000
E26.9 Hyperaldosteronism, unspecified	0.465	0.535	0.000
E23 Hypofunction and other disorders of pituitary gland	0.465	0.535	0.000
E26.0 Primary hyperaldosteronism	0.459	0.541	0.000
E44 Protein-energy malnutrition of moderate and mild degree	0.457	0.543	0.000
E45 Retarded development following protein-energy malnutrition	0.457	0.543	0.000
E43 Unspecified severe protein-energy malnutrition	0.457	0.543	0.000
E42 Marasmic kwashiorkor	0.457	0.543	0.000
E41 Nutritional marasmus	0.457	0.543	0.000
E40 Kwashiorkor	0.457	0.543	0.000
E11.5 With peripheral circulatory complications	0.454	0.546	0.000
E24.9 Cushing's syndrome, unspecified	0.448	0.552	0.000
E34 Other endocrine disorders	0.446	0.554	0.000
E15 Nondiabetic hypoglycaemic coma	0.439	0.561	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.428	0.572	0.000
E20 Hypoparathyroidism	0.420	0.580	0.000
E13.8 With unspecified complications	0.420	0.580	0.000
E13.7 With multiple complications	0.420	0.580	0.000
E13.6 With other specified complications	0.420	0.580	0.000
E13.5 With peripheral circulatory complications	0.420	0.580	0.000
E13.4 With neurological complications	0.420	0.580	0.000
E13.3 With ophthalmic complications	0.420	0.580	0.000
E13.2 With renal complications	0.420	0.580	0.000
E13.1 With ketoacidosis	0.420	0.580	0.000
E13.0 With coma	0.420	0.580	0.000
E26.8 Other hyperaldosteronism	0.412	0.588	0.000
E26.1 Secondary hyperaldosteronism	0.412	0.588	0.000
E10.1 With ketoacidosis	0.407	0.593	0.000
E46 Unspecified protein-energy malnutrition	0.406	0.593	0.000
E61.2 Magnesium deficiency	0.397	0.603	0.000
E53.8 Deficiency of other specified B group vitamins	0.390	0.610	0.000
E24.8 Other Cushing's syndrome	0.387	0.613	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.387	0.613	0.000
E24.3 Ectopic ACTH syndrome	0.387	0.613	0.000
E24.2 Drug-induced Cushing's syndrome	0.387	0.613	0.000
E24.1 Nelson's syndrome	0.387	0.613	0.000
E53.9 Vitamin B deficiency, unspecified	0.383	0.617	0.000
E53.1 Pyridoxine deficiency	0.380	0.620	0.000
E53.0 Riboflavin deficiency	0.380	0.620	0.000
E24.0 Pituitary-dependent Cushing's disease	0.371	0.629	0.000
E50.9 Vitamin A deficiency, unspecified	0.370	0.630	0.000
E50.8 Other manifestations of vitamin A deficiency	0.370	0.630	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.370	0.630	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.370	0.630	0.000
E50.5 Vitamin A deficiency with night blindness	0.370	0.630	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.370	0.630	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.370	0.630	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.370	0.630	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.370	0.630	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.370	0.630	0.000
E51.9 Thiamine deficiency, unspecified	0.370	0.630	0.000
E51.8 Other manifestations of thiamine deficiency	0.370	0.630	0.000
E51.2 Wernicke's encephalopathy	0.370	0.630	0.000
E51.1 Beriberi	0.370	0.630	0.000
E56.9 Vitamin deficiency, unspecified	0.370	0.630	0.000
E56.8 Deficiency of other vitamins	0.370	0.630	0.000
E56.1 Deficiency of vitamin K	0.370	0.630	0.000
E56.0 Deficiency of vitamin E	0.370	0.630	0.000
E63.9 Nutritional deficiency, unspecified	0.370	0.630	0.000
E63.8 Other specified nutritional deficiencies	0.370	0.630	0.000
E63.1 Imbalance of constituents of food intake	0.370	0.630	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.370	0.630	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.370	0.630	0.000
E64.8 Sequelae of other nutritional deficiencies	0.370	0.630	0.000
E64.3 Sequelae of rickets	0.370	0.630	0.000
E64.2 Sequelae of vitamin C deficiency	0.370	0.630	0.000
E64.1 Sequelae of vitamin A deficiency	0.370	0.630	0.000
E64.0 Sequelae of protein-energy malnutrition	0.370	0.630	0.000
E23.2 Diabetes insipidus	0.368	0.632	0.000
E61.9 Deficiency of nutrient element, unspecified	0.367	0.633	0.000
E61.8 Deficiency of other specified nutrient elements	0.367	0.633	0.000
E61.7 Deficiency of multiple nutrient elements	0.367	0.633	0.000
E61.6 Vanadium deficiency	0.367	0.633	0.000
E61.5 Molybdenum deficiency	0.367	0.633	0.000
E61.4 Chromium deficiency	0.367	0.633	0.000
E61.3 Manganese deficiency	0.367	0.633	0.000
E61.0 Copper deficiency	0.367	0.633	0.000
E16 Other disorders of pancreatic internal secretion	0.363	0.637	0.000
E29 Testicular dysfunction	0.355	0.644	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.352	0.648	0.000
E22.8 Other hyperfunction of pituitary gland	0.352	0.648	0.000
E55.0 Rickets, active	0.351	0.649	0.000
E25.9 Adrenogenital disorder, unspecified	0.351	0.649	0.000
E25.8 Other adrenogenital disorders	0.351	0.649	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.351	0.649	0.000
E30.9 Disorder of puberty, unspecified	0.351	0.649	0.000
E30.8 Other disorders of puberty	0.351	0.649	0.000
E30.1 Precocious puberty	0.351	0.649	0.000
E30.0 Delayed puberty	0.351	0.649	0.000
E31.9 Polyglandular dysfunction, unspecified	0.351	0.649	0.000
E31.8 Other polyglandular dysfunction	0.351	0.649	0.000
E31.1 Polyglandular hyperfunction	0.351	0.649	0.000
E31.0 Autoimmune polyglandular failure	0.351	0.649	0.000
E32.9 Disease of thymus, unspecified	0.351	0.649	0.000
E32.8 Other diseases of thymus	0.351	0.649	0.000
E32.1 Abscess of thymus	0.351	0.649	0.000
E32.0 Persistent hyperplasia of thymus	0.351	0.649	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.351	0.649	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.351	0.649	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.351	0.649	0.000
E10.4 With neurological complications	0.347	0.653	0.001
E11.0 With coma	0.343	0.656	0.001
E23.6 Other disorders of pituitary gland	0.341	0.659	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.334	0.666	0.000
E23.1 Drug-induced hypopituitarism	0.334	0.666	0.000
E34.9 Endocrine disorder, unspecified	0.329	0.671	0.000
E44.1 Mild protein-energy malnutrition	0.328	0.672	0.000
E44.0 Moderate protein-energy malnutrition	0.328	0.672	0.000
E55.9 Vitamin D deficiency, unspecified	0.325	0.675	0.000
E61.1 Iron deficiency	0.323	0.676	0.000
E23.7 Disorder of pituitary gland, unspecified	0.320	0.680	0.000
E34.5 Androgen resistance syndrome	0.320	0.680	0.000
E34.4 Constitutional tall stature	0.320	0.680	0.000
E34.3 Short stature, not elsewhere classified	0.320	0.680	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.320	0.680	0.000
E34.1 Other hypersecretion of intestinal hormones	0.320	0.680	0.000
E34.0 Carcinoid syndrome	0.319	0.681	0.000
E22.0 Acromegaly and pituitary gigantism	0.303	0.697	0.000
E20.8 Other hypoparathyroidism	0.301	0.698	0.000
E20.1 Pseudohypoparathyroidism	0.301	0.698	0.000
E20.0 Idiopathic hypoparathyroidism	0.301	0.698	0.000
E13.9 Without complications	0.298	0.702	0.000
E22.1 Hyperprolactinaemia	0.268	0.732	0.000
E34.8 Other specified endocrine disorders	0.265	0.734	0.000
E23.0 Hypopituitarism	0.264	0.736	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.260	0.740	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.260	0.740	0.000
E16.4 Abnormal secretion of gastrin	0.260	0.740	0.000
E16.3 Increased secretion of glucagon	0.260	0.740	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.256	0.743	0.000
E29.9 Testicular dysfunction, unspecified	0.255	0.745	0.000
E29.8 Other testicular dysfunction	0.255	0.745	0.000
E29.0 Testicular hyperfunction	0.255	0.745	0.000
E16.1 Other hypoglycaemia	0.249	0.751	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.236	0.764	0.000
E16.2 Hypoglycaemia, unspecified	0.233	0.767	0.000
E20.9 Hypoparathyroidism, unspecified	0.232	0.767	0.000
I10-I15 Hypertensive diseases	0.188	0.812	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.185	0.814	0.000
E21.4 Other specified disorders of parathyroid gland	0.184	0.816	0.000
E21.2 Other hyperparathyroidism	0.184	0.816	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.160	0.839	0.000
E21.3 Hyperparathyroidism, unspecified	0.153	0.847	0.000
I13 Hypertensive heart and renal disease	0.135	0.865	0.000
E27 Other disorders of adrenal gland	0.130	0.869	0.001
I11 Hypertensive heart disease	0.130	0.870	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.125	0.875	0.000
E29.1 Testicular hypofunction	0.121	0.878	0.001
I25.2 Old myocardial infarction	0.110	0.890	0.000
I25 Chronic ischaemic heart disease	0.108	0.892	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.108	0.892	0.000
I15 Secondary hypertension	0.103	0.897	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.097	0.903	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.097	0.903	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.097	0.903	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.097	0.903	0.000
I12 Hypertensive renal disease	0.095	0.905	0.000
E27.5 Adrenomedullary hyperfunction	0.093	0.906	0.001
E27.0 Other adrenocortical overactivity	0.093	0.906	0.001
E21.0 Primary hyperparathyroidism	0.091	0.909	0.000
I20-I25 Ischaemic heart diseases	0.090	0.910	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.088	0.911	0.001
Z95.1 Presence of aortocoronary bypass graft	0.086	0.914	0.000
E27.8 Other specified disorders of adrenal gland	0.084	0.915	0.001
E27.9 Disorder of adrenal gland, unspecified	0.082	0.918	0.001
E27.2 Addisonian crisis	0.080	0.919	0.001
I20.9 Angina pectoris, unspecified	0.079	0.921	0.000
I25.6 Silent myocardial ischaemia	0.078	0.922	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.078	0.922	0.000
I22 Subsequent myocardial infarction	0.077	0.923	0.000
I20 Angina pectoris	0.075	0.925	0.000
I15.9 Seconday hypertension, unspecified	0.074	0.926	0.000
I15.8 Other secondary hypertension	0.074	0.926	0.000
I15.2 Hypertension secondary to endocrine disorders	0.074	0.926	0.000
I15.0 Renovascular hypertension	0.074	0.926	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.073	0.927	0.000
I12.9 Hypertensive renal disease without renal failure	0.072	0.928	0.000
E00-E07 Disorders of thyroid gland	0.071	0.929	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.070	0.929	0.001
I21 Acute myocardial infarction	0.069	0.931	0.000
Chapter IX Diseases of the circulatory system	0.069	0.931	0.000
I25.4 Coronary artery aneurysm	0.068	0.931	0.000
I25.3 Aneurysm of heart	0.066	0.934	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.064	0.936	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.063	0.936	0.000
I23 Certain current complications following acute myocardial infarction	0.063	0.937	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.060	0.940	0.000
I21.3 Acute transmural myocardial infarction of unspecified site	0.060	0.940	0.000
I25.5 Ischaemic cardiomyopathy	0.058	0.942	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.057	0.943	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.054	0.946	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.051	0.949	0.000
E00 Congenital iodine-deficiency syndrome	0.051	0.949	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.051	0.949	0.000
I21.X Presumed acute myicardial infaction (unconfirmed)	0.050	0.950	0.000
I00-I02 Acute rheumatic fever	0.050	0.950	0.000
I05-I09 Chronic rheumatic heart diseases	0.049	0.951	0.000
I21.4 Acute subendocardial myocardial infarction	0.048	0.952	0.000
I22.1 Subsequent myocardial infarction of inferior wall	0.048	0.952	0.000
I27 Other pulmonary heart diseases	0.046	0.954	0.000
I22.8 Subsequent myocardial infarction of other sites	0.046	0.954	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.045	0.955	0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.045	0.955	0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.045	0.955	0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.045	0.955	0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.045	0.955	0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.045	0.955	0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.045	0.955	0.000
I21.9 Acute myocardial infarction, unspecified	0.044	0.956	0.000
I27.0 Primary pulmonary hypertension	0.043	0.957	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.043	0.957	0.000
I23.8 Other current complications following acute myocardial infarction	0.043	0.957	0.000
I15.1 Hypertension secondary to other renal disorders	0.041	0.958	0.001
E05 Thyrotoxicosis [hyperthyroidism]	0.040	0.960	0.000
I28 Other diseases of pulmonary vessels	0.039	0.961	0.000
I08 Multiple valve diseases	0.038	0.962	0.000
I05 Rheumatic mitral valve diseases	0.037	0.963	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.037	0.963	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.037	0.963	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.037	0.963	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.037	0.963	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.037	0.963	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.037	0.963	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.037	0.963	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.037	0.963	0.000
E27.1 Primary adrenocortical insufficiency	0.035	0.963	0.001
I27.2 Other secondary pulmonary hypertension	0.036	0.964	0.000
I06 Rheumatic aortic valve diseases	0.036	0.964	0.000
I02 Rheumatic chorea	0.036	0.964	0.000
I01 Rheumatic fever with heart involvement	0.036	0.964	0.000
I00 Rheumatic fever without mention of heart involvement	0.036	0.964	0.000
I51.9 Heart disease, unspecified	0.034	0.966	0.000
E05.8 Other thyrotoxicosis	0.034	0.966	0.000
I27.1 Kyphoscoliotic heart disease	0.033	0.966	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.033	0.967	0.000
I24 Other acute ischaemic heart diseases	0.032	0.967	0.000
I26 Pulmonary embolism	0.032	0.968	0.000
E06 Thyroiditis	0.031	0.968	0.000
I05.1 Rheumatic mitral insufficiency	0.032	0.968	0.000
I27.8 Other specified pulmonary heart diseases	0.031	0.969	0.000
I09 Other rheumatic heart diseases	0.031	0.969	0.000
E07 Other disorders of thyroid	0.031	0.969	0.000
E03 Other hypothyroidism	0.031	0.969	0.000
I05.9 Mitral valve disease, unspecified	0.030	0.970	0.000
I20.0 Unstable angina	0.030	0.970	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.030	0.970	0.000
I07 Rheumatic tricuspid valve diseases	0.029	0.971	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.029	0.971	0.000
E05.5 Thyroid crisis or storm	0.029	0.971	0.000
E05.4 Thyrotoxicosis factitia	0.029	0.971	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.029	0.971	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.029	0.971	0.000
I28.8 Other specified diseases of pulmonary vessels	0.029	0.971	0.000
I08.9 Multiple valve disease, unspecified	0.029	0.971	0.000
I06.1 Rheumatic aortic insufficiency	0.028	0.971	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.028	0.972	0.000
I28.1 Aneurysm of pulmonary artery	0.028	0.972	0.000
I28.0 Arteriovenous fistula of pulmonary vessels	0.028	0.972	0.000
K26.4 Chronic or unspecified with haemorrhage	0.028	0.972	0.000
I05.8 Other mitral valve diseases	0.027	0.973	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.027	0.973	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.027	0.973	0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.027	0.973	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.026	0.974	0.000
I06.8 Other rheumatic aortic valve diseases	0.026	0.974	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.026	0.974	0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.000	0.974	0.026
I08.0 Disorders of both mitral and aortic valves	0.026	0.974	0.000
K26 Duodenal ulcer	0.026	0.974	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.026	0.974	0.000
I01.8 Other acute rheumatic heart disease	0.026	0.974	0.000
I01.2 Acute rheumatic myocarditis	0.026	0.974	0.000
I01.1 Acute rheumatic endocarditis	0.026	0.974	0.000
I01.0 Acute rheumatic pericarditis	0.026	0.974	0.000
I02.9 Rheumatic chorea without heart involvement	0.026	0.974	0.000
I02.0 Rheumatic chorea with heart involvement	0.026	0.974	0.000
I72 Other aneurysm	0.026	0.974	0.000
I27.9 Pulmonary heart disease, unspecified	0.025	0.975	0.000
I08.8 Other multiple valve diseases	0.025	0.975	0.000
I06.0 Rheumatic aortic stenosis	0.024	0.975	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.024	0.976	0.000
E05.9 Thyrotoxicosis, unspecified	0.024	0.976	0.000
Z48.0 Attention to surgical dressings and sutures	0.024	0.976	0.000
E03.1 Congenital hypothyroidism without goitre	0.024	0.976	0.000
I72.3 Aneurysm of iliac artery	0.024	0.976	0.000
K26.3 Acute without haemorrhage or perforation	0.024	0.976	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.023	0.977	0.000
I74 Arterial embolism and thrombosis	0.023	0.977	0.000
I05.0 Mitral stenosis	0.023	0.977	0.000
E06.5 Other chronic thyroiditis	0.022	0.977	0.000
E06.4 Drug-induced thyroiditis	0.022	0.977	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.022	0.977	0.000
E06.1 Subacute thyroiditis	0.022	0.977	0.000
E06.0 Acute thyroiditis	0.022	0.977	0.000
I25.1 Atherosclerotic heart disease	0.023	0.977	0.000
I09.8 Other specified rheumatic heart diseases	0.022	0.977	0.000
I09.2 Chronic rheumatic pericarditis	0.022	0.977	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.022	0.977	0.000
I09.0 Rheumatic myocarditis	0.022	0.977	0.000
I05.2 Mitral stenosis with insufficiency	0.022	0.977	0.000
K26.5 Chronic or unspecified with perforation	0.023	0.977	0.000
E07.1 Dyshormogenetic goitre	0.022	0.977	0.000
E07.0 Hypersecretion of calcitonin	0.022	0.977	0.000
E70-E90 Metabolic disorders	0.022	0.978	0.000
E03.5 Myxoedema coma	0.022	0.978	0.000
E03.4 Atrophy of thyroid (acquired)	0.022	0.978	0.000
E03.3 Postinfectious hypothyroidism	0.022	0.978	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.022	0.978	0.000
I72.2 Aneurysm of renal artery	0.022	0.978	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.022	0.978	0.000
I78 Diseases of capillaries	0.022	0.978	0.000
I70 Atherosclerosis	0.021	0.979	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.021	0.979	0.000
I07.9 Tricuspid valve disease, unspecified	0.021	0.979	0.000
I07.8 Other tricuspid valve diseases	0.021	0.979	0.000
I07.2 Tricuspid stenosis with insufficiency	0.021	0.979	0.000
I07.0 Tricuspid stenosis	0.021	0.979	0.000
I24.1 Dressler's syndrome	0.021	0.979	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.021	0.979	0.000
I20.1 Angina pectoris with documented spasm	0.020	0.979	0.001
E06.9 Thyroiditis, unspecified	0.020	0.979	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.021	0.979	0.000
E03.8 Other specified hypothyroidism	0.020	0.980	0.000
I72.0 Aneurysm of carotid artery	0.020	0.980	0.000
C71 Malignant neoplasm of brain	0.000	0.980	0.020
E04 Other non-toxic goitre	0.020	0.980	0.000
C71.9 Brain, unspecified	0.000	0.980	0.020
I46.9 Cardiac arrest, unspecified	0.020	0.980	0.000
K26.0 Acute with haemorrhage	0.020	0.980	0.000
K26.1 Acute with perforation	0.019	0.981	0.000
I20.8 Other forms of angina pectoris	0.019	0.981	0.000
K26.2 Acute with both haemorrhage and perforation	0.019	0.981	0.000
C71.2 Temporal lobe	0.000	0.981	0.019
I72.6 Aneurysm and dissection of vertebral artery	0.019	0.981	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.019	0.981	0.000
I72.1 Aneurysm of artery of upper extremity	0.019	0.981	0.000
I09.9 Rheumatic heart disease, unspecified	0.018	0.981	0.000
I72.8 Aneurysm of other specified arteries	0.019	0.981	0.000
I74.8 Embolism and thrombosis of other arteries	0.018	0.981	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.018	0.982	0.000
E74 Other disorders of carbohydrate metabolism	0.018	0.982	0.000
I72.9 Aneurysm of unspecified site	0.018	0.982	0.000
I12.0 Hypertensive renal disease with renal failure	0.018	0.982	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.018	0.982	0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.018	0.982	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.018	0.982	0.000
C71.3 Parietal lobe	0.000	0.982	0.018
C71.1 Frontal lobe	0.000	0.982	0.018
E07.8 Other specified disorders of thyroid	0.017	0.982	0.000
I78.9 Disease of capillaries, unspecified	0.017	0.982	0.000
I70.0 Atherosclerosis of aorta	0.017	0.983	0.000
I70.8 Atherosclerosis of other arteries	0.017	0.983	0.000
C71.0 Cerebrum, except lobes and ventricles	0.000	0.983	0.017
E80 Disorders of porphyrin and bilirubin metabolism	0.017	0.983	0.000
E85 Amyloidosis	0.017	0.983	0.000
Z95.2 Presence of prosthetic heart valve	0.016	0.984	0.000
I46 Cardiac arrest	0.016	0.984	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.016	0.984	0.000
E84 Cystic fibrosis	0.016	0.984	0.000
E79 Disorders of purine and pyrimidine metabolism	0.016	0.984	0.000
E77 Disorders of glycoprotein metabolism	0.016	0.984	0.000
E76 Disorders of glycosaminoglycan metabolism	0.016	0.984	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.016	0.984	0.000
E72 Other disorders of amino-acid metabolism	0.016	0.984	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.016	0.984	0.000
E70 Disorders of aromatic amino-acid metabolism	0.016	0.984	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.016	0.984	0.000
I51 Complications and ill-defined descriptions of heart disease	0.016	0.984	0.000
I30-I52 Other forms of heart disease	0.016	0.984	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.016	0.984	0.000
I78.8 Other diseases of capillaries	0.016	0.984	0.000
I70.9 Generalised and unspecified atherosclerosis	0.015	0.984	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.015	0.984	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.015	0.985	0.000
I70.1 Atherosclerosis of renal artery	0.015	0.985	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.015	0.985	0.000
I79.1 Aortitis in diseases classified elsewhere	0.015	0.985	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.015	0.985	0.000
I07.1 Tricuspid insufficiency	0.015	0.985	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.015	0.985	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.015	0.985	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.015	0.985	0.000
C71.7 Brain stem	0.000	0.985	0.015
C71.6 Cerebellum	0.000	0.985	0.015
C71.5 Cerebral ventricle	0.000	0.985	0.015
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.014	0.985	0.000
I73 Other peripheral vascular diseases	0.015	0.985	0.000
E04.8 Other specified non-toxic goitre	0.014	0.985	0.000
E73 Lactose intolerance	0.014	0.986	0.000
I78.1 Naevus, nonneoplastic	0.014	0.986	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.014	0.986	0.000
C71.8 Overlapping lesion of brain	0.000	0.986	0.014
C71.4 Occipital lobe	0.000	0.986	0.014
I70.80 Atherosclerosis of other arteries (without gangrene)	0.014	0.986	0.000
E80.6 Other disorders of bilirubin metabolism	0.014	0.986	0.000
Z95.4 Presence of other heart-valve replacement	0.014	0.986	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.000	0.986	0.014
I31 Other diseases of pericardium	0.014	0.986	0.000
E85.8 Other amyloidosis	0.014	0.986	0.000
I72.4 Aneurysm of artery of lower extremity	0.013	0.987	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.013	0.987	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.013	0.987	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.013	0.987	0.000
E74.2 Disorders of galactose metabolism	0.013	0.987	0.000
E74.1 Disorders of fructose metabolism	0.013	0.987	0.000
E74.0 Glycogen storage disease	0.013	0.987	0.000
E88 Other metabolic disorders	0.013	0.987	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.013	0.987	0.000
G43.1 Migraine with aura [classical migraine]	0.000	0.987	0.013
E83 Disorders of mineral metabolism	0.013	0.987	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations