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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10136659
log Bayes Factor = 14.3641
Chromosome 14   position 65,377,610  (GRCh37) Explore rs10136659 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
Chapter IX Diseases of the circulatory system
0.995 0.005 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.995 0.005 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.994 0.006 0.000
Z72 Problems related to lifestyle
0.992 0.008 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.992 0.008 0.000
Chapter XXI Factors influencing health status and contact with health services
0.991 0.009 0.000
Z72.0 Tobacco use
0.990 0.010 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.988 0.012 0.000
Chapter XX External causes of morbidity and mortality
0.987 0.013 0.000
I60-I69 Cerebrovascular diseases
0.986 0.014 0.000
R50-R69 General symptoms and signs
0.986 0.014 0.000
Chapter I Certain infectious and parasitic diseases
0.978 0.022 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.974 0.026 0.000
R50 Fever of unknown origin
0.971 0.029 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.970 0.030 0.000
C79 Secondary malignant neoplasm of other sites
0.966 0.034 0.000
F30-F39 Mood [affective] disorders
0.964 0.036 0.000
R50.9 Fever, unspecified
0.955 0.045 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.954 0.046 0.000
M70-M79 Other soft tissue disorders
0.950 0.050 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.948 0.052 0.000
S60-S69 Injuries to the wrist and hand
0.948 0.052 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.947 0.053 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.936 0.064 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.935 0.065 0.000
Z72.1 Alcohol use
0.934 0.066 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.931 0.069 0.000
F32 Depressive episode
0.926 0.074 0.000
I63 Cerebral infarction
0.924 0.076 0.000
Y57 Other and unspecified drugs and medicaments
0.919 0.081 0.000
R55 Syncope and collapse
0.918 0.082 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.918 0.082 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.913 0.087 0.000
D50-D53 Nutritional anaemias
0.911 0.089 0.000
A00-A09 Intestinal infectious diseases
0.910 0.090 0.000
R47-R49 Symptoms and signs involving speech and voice
0.907 0.093 0.000
Chapter XI Diseases of the digestive system
0.905 0.095 0.000
O60-O75 Complications of labour and delivery
0.902 0.098 0.000
I30-I52 Other forms of heart disease
0.901 0.099 0.000
M45-M49 Spondylopathies
0.899 0.101 0.000
F32.9 Depressive episode, unspecified
0.897 0.103 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.893 0.107 0.000
R51 Headache
0.888 0.112 0.000
C50-C50 Malignant neoplasm of breast
0.887 0.113 0.000
Y57.9 Drug or medicament, unspecified
0.883 0.117 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.882 0.118 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.874 0.126 0.000
A04 Other bacterial intestinal infections
0.872 0.128 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.869 0.131 0.000
Chapter XIV Diseases of the genitourinary system
0.868 0.132 0.000
K70-K77 Diseases of liver
0.863 0.137 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.860 0.140 0.000
S62 Fracture at wrist and hand level
0.860 0.140 0.000
R47 Speech disturbances, not elsewhere classified
0.857 0.143 0.000
D00-D09 In situ neoplasms
0.855 0.145 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.850 0.150 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.849 0.151 0.000
F10.2 Dependence syndrome
0.844 0.156 0.000
K65-K67 Diseases of peritoneum
0.842 0.158 0.000
Chapter VI Diseases of the nervous system
0.840 0.160 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.839 0.161 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.838 0.162 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.835 0.165 0.000
D10-D36 Benign neoplasms
0.835 0.165 0.000
Y43 Primarily systemic agents
0.833 0.167 0.000
I61 Intracerebral haemorrhage
0.830 0.170 0.000
I63.9 Cerebral infarction, unspecified
0.830 0.170 0.000
W00-W19 Falls
0.829 0.171 0.000
M79.8 Other specified soft tissue disorders
0.829 0.171 0.000
C51-C58 Malignant neoplasms of female genital organs
0.828 0.172 0.000
Chapter VIII Diseases of the ear and mastoid process
0.827 0.173 0.000
R68 Other general symptoms and signs
0.826 0.174 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.825 0.175 0.000
B35-B49 Mycoses
0.825 0.175 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.823 0.177 0.000
M80-M85 Disorders of bone density and structure
0.820 0.180 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.819 0.181 0.000
O70 Perineal laceration during delivery
0.818 0.182 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.817 0.183 0.000
I60 Subarachnoid haemorrhage
0.817 0.183 0.000
M79.6 Pain in limb
0.817 0.183 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.816 0.184 0.000
C64-C68 Malignant neoplasms of urinary tract
0.816 0.184 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.814 0.186 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.814 0.186 0.000
T66-T78 Other and unspecified effects of external causes
0.814 0.186 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.813 0.187 0.000
D50 Iron deficiency anaemia
0.813 0.187 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.811 0.189 0.000
R54 Senility
0.809 0.191 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.809 0.191 0.000
C50 Malignant neoplasm of breast
0.807 0.193 0.000
R42 Dizziness and giddiness
0.805 0.195 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.805 0.195 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.805 0.195 0.000
O72 Postpartum haemorrhage
0.801 0.199 0.000
I50 Heart failure
0.800 0.200 0.000
F10.1 Harmful use
0.799 0.201 0.000
O70.0 First degree perineal laceration during delivery
0.799 0.201 0.000
K66 Other disorders of peritoneum
0.799 0.201 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.798 0.202 0.000
M05-M14 Inflammatory polyarthropathies
0.797 0.203 0.000
K70 Alcoholic liver disease
0.794 0.206 0.000
B95-B98 Bacterial, viral and other infectious agents
0.794 0.206 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.794 0.206 0.000
L03 Cellulitis
0.793 0.207 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.792 0.208 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.791 0.209 0.000
R56 Convulsions, not elsewhere classified
0.790 0.210 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.789 0.211 0.000
I62 Other nontraumatic intracranial haemorrhage
0.788 0.212 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.787 0.213 0.000
X60-X84 Intentional self-harm
0.787 0.213 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.785 0.215 0.000
R94 Abnormal results of function studies
0.784 0.216 0.000
I35 Nonrheumatic aortic valve disorders
0.784 0.216 0.000
I05-I09 Chronic rheumatic heart diseases
0.784 0.216 0.000
I31 Other diseases of pericardium
0.782 0.218 0.000
M47 Spondylosis
0.782 0.218 0.000
S20-S29 Injuries to the thorax
0.782 0.218 0.000
T79-T79 Certain early complications of trauma
0.781 0.219 0.000
Z74 Problems related to care-provider dependency
0.781 0.219 0.000
N72 Inflammatory disease of cervix uteri
0.781 0.219 0.000
D51 Vitamin B12 deficiency anaemia
0.781 0.219 0.000
A30-A49 Other bacterial diseases
0.778 0.222 0.000
W20-W49 Exposure to inanimate mechanical forces
0.778 0.222 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.777 0.223 0.000
S65 Injury of blood vessels at wrist and hand level
0.777 0.223 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.777 0.223 0.000
R47.8 Other and unspecified speech disturbances
0.776 0.224 0.000
Z75 Problems related to medical facilities and other health care
0.776 0.224 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.775 0.225 0.000
D52 Folate deficiency anaemia
0.772 0.228 0.000
I65.2 Occlusion and stenosis of carotid artery
0.771 0.229 0.000
D23 Other benign neoplasms of skin
0.770 0.230 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.770 0.230 0.000
M86-M90 Other osteopathies
0.769 0.231 0.000
K66.0 Peritoneal adhesions
0.769 0.231 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.768 0.232 0.000
L03.1 Cellulitis of other parts of limb
0.765 0.235 0.000
L05 Pilonidal cyst
0.765 0.235 0.000
R50.0 Fever with chills
0.764 0.236 0.000
M75 Shoulder lesions
0.764 0.236 0.000
F31 Bipolar affective disorder
0.761 0.239 0.000
S10-S19 Injuries to the neck
0.759 0.241 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.759 0.241 0.000
O85-O92 Complications predominantly related to the puerperium
0.758 0.242 0.000
R57 Shock, not elsewhere classified
0.758 0.242 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.757 0.243 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.757 0.243 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.755 0.245 0.000
M91-M94 Chondropathies
0.755 0.245 0.000
C79.2 Secondary malignant neoplasm of skin
0.753 0.247 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.753 0.247 0.000
V10-V19 Pedal cyclist injured in transport accident
0.750 0.250 0.000
S62.6 Fracture of other finger
0.750 0.250 0.000
D24 Benign neoplasm of breast
0.749 0.251 0.000
K81 Cholecystitis
0.747 0.253 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.745 0.255 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.744 0.256 0.000
M46 Other inflammatory spondylopathies
0.742 0.258 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.741 0.259 0.000
N40-N51 Diseases of male genital organs
0.740 0.260 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.737 0.262 0.000
T92 Sequelae of injuries of upper limb
0.736 0.264 0.000
F99-F99 Unspecified mental disorder
0.736 0.264 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.736 0.264 0.000
Y43.3 Other antineoplastic drugs
0.735 0.265 0.000
Y52 Agents primarily affecting the cardiovascular system
0.734 0.266 0.000
S70-S79 Injuries to the hip and thigh
0.734 0.266 0.000
R50.8 Other specified fever
0.734 0.266 0.000
S60 Superficial injury of wrist and hand
0.732 0.268 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.732 0.268 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.731 0.269 0.000
D23.5 Skin of trunk
0.731 0.269 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.730 0.270 0.000
M75.0 Adhesive capsulitis of shoulder
0.730 0.270 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.730 0.270 0.000
I44 Atrioventricular and left bundle-branch block
0.730 0.270 0.000
K74 Fibrosis and cirrhosis of liver
0.729 0.271 0.000
F33 Recurrent depressive disorder
0.727 0.273 0.000
C50.4 Upper-outer quadrant of breast
0.727 0.273 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.724 0.275 0.000
Y44 Agents primarily affecting blood constituents
0.724 0.276 0.000
L08 Other local infections of skin and subcutaneous tissue
0.724 0.276 0.000
F42 Obsessive-compulsive disorder
0.724 0.276 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.723 0.277 0.000
G20-G26 Extrapyramidal and movement disorders
0.723 0.277 0.000
R61 Hyperhidrosis
0.722 0.278 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.721 0.279 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.721 0.279 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.721 0.279 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.720 0.280 0.000
M48 Other spondylopathies
0.719 0.281 0.000
A04.5 Campylobacter enteritis
0.719 0.281 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.718 0.281 0.000
I50.9 Heart failure, unspecified
0.718 0.282 0.000
S67 Crushing injury of wrist and hand
0.718 0.282 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R47.0 Dysphasia and aphasia
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.716 0.284 0.000
I67 Other cerebrovascular diseases
0.716 0.284 0.000
K50-K52 Noninfective enteritis and colitis
0.716 0.284 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F80-F89 Disorders of psychological development
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
F60-F69 Disorders of adult personality and behaviour
0.715 0.285 0.000
I00-I02 Acute rheumatic fever
0.714 0.286 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.713 0.287 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.713 0.287 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
S90-S99 Injuries to the ankle and foot
0.713 0.287 0.000
M77 Other enthesopathies
0.712 0.287 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.712 0.288 0.000
R68.8 Other specified general symptoms and signs
0.712 0.288 0.000
M65-M68 Disorders of synovium and tendon
0.711 0.289 0.000
I74 Arterial embolism and thrombosis
0.711 0.289 0.000
Z72.9 Problem related to lifestyle, unspecified
0.711 0.289 0.000
Z72.8 Other problems related to lifestyle
0.711 0.289 0.000
Z72.6 Gambling and betting
0.711 0.289 0.000
Z72.5 High-risk sexual behaviour
0.711 0.289 0.000
Z72.4 Inappropriate diet and eating habits
0.711 0.289 0.000
Z72.3 Lack of physical exercise
0.711 0.289 0.000
Z72.2 Drug use
0.711 0.289 0.000
Z76 Persons encountering health services in other circumstances
0.711 0.289 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.711 0.289 0.000
Chapter XXII Codes for special purposes
0.711 0.289 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.711 0.289 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.710 0.290 0.000
H90-H95 Other disorders of ear
0.710 0.290 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.709 0.290 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.708 0.292 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.708 0.292 0.000
Y35-Y36 Legal intervention and operations of war
0.708 0.292 0.000
Y10-Y34 Event of undetermined intent
0.708 0.292 0.000
Y00-Y09 Assault
0.708 0.292 0.000
X85-X99 Assault
0.708 0.292 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.708 0.292 0.000
X50-X57 Overexertion, travel and privation
0.708 0.292 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.708 0.292 0.000
X30-X39 Exposure to forces of nature
0.708 0.292 0.000
X20-X29 Contact with venomous animals and plants
0.708 0.292 0.000
X10-X19 Contact with heat and hot substances
0.708 0.292 0.000
X00-X09 Exposure to smoke, fire and flames
0.708 0.292 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.708 0.292 0.000
W75-W84 Other accidental threats to breathing
0.708 0.292 0.000
W65-W74 Accidental drowning and submersion
0.708 0.292 0.000
W50-W64 Exposure to animate mechanical forces
0.708 0.292 0.000
V98-V99 Other and unspecified transport accidents
0.708 0.292 0.000
V95-V97 Air and space transport accidents
0.708 0.292 0.000
V90-V94 Water transport accidents
0.708 0.292 0.000
V80-V89 Other land transport accidents
0.708 0.292 0.000
V70-V79 Bus occupant injured in transport accident
0.708 0.292 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.708 0.292 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.708 0.292 0.000
V40-V49 Car occupant injured in transport accident
0.708 0.292 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.708 0.292 0.000
V20-V29 Motorcycle rider injured in transport accident
0.708 0.292 0.000
V01-V09 Pedestrian injured in transport accident
0.708 0.292 0.000
T42.4 Benzodiazepines
0.707 0.293 0.000
I46 Cardiac arrest
0.707 0.293 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.707 0.293 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.707 0.293 0.000
F10.3 Withdrawal state
0.707 0.293 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.707 0.293 0.000
R62 Lack of expected normal physiological development
0.707 0.293 0.000
R64 Cachexia
0.707 0.293 0.000
R58 Haemorrhage, not elsewhere classified
0.707 0.293 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.707 0.293 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.706 0.294 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.705 0.295 0.000
B35 Dermatophytosis
0.704 0.296 0.000
M79.7 Fibromyalgia
0.704 0.296 0.000
I31.3 Pericardial effusion (noninflammatory)
0.703 0.297 0.000
O72.1 Other immediate postpartum haemorrhage
0.703 0.297 0.000
S50-S59 Injuries to the elbow and forearm
0.702 0.298 0.000
B99-B99 Other infectious diseases
0.701 0.299 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.701 0.299 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.701 0.299 0.000
B65-B83 Helminthiases
0.701 0.299 0.000
B50-B64 Protozoal diseases
0.701 0.299 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.701 0.299 0.000
B15-B19 Viral hepatitis
0.701 0.299 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.701 0.299 0.000
A80-A89 Viral infections of the central nervous system
0.701 0.299 0.000
A75-A79 Rickettsioses
0.701 0.299 0.000
A70-A74 Other diseases caused by chlamydiae
0.701 0.299 0.000
A65-A69 Other spirochaetal diseases
0.701 0.299 0.000
A20-A28 Certain zoonotic bacterial diseases
0.701 0.299 0.000
A15-A19 Tuberculosis
0.701 0.299 0.000
M06 Other rheumatoid arthritis
0.701 0.299 0.000
L20-L30 Dermatitis and eczema
0.700 0.300 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.700 0.300 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.700 0.300 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.699 0.301 0.000
M80 Osteoporosis with pathological fracture
0.699 0.301 0.000
M60-M63 Disorders of muscles
0.699 0.301 0.000
M00-M03 Infectious arthropathies
0.699 0.301 0.000
R53 Malaise and fatigue
0.699 0.301 0.000
M47.8 Other spondylosis
0.697 0.303 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.697 0.303 0.000
R94.5 Abnormal results of liver function studies
0.697 0.303 0.000
D11 Benign neoplasm of major salivary glands
0.697 0.303 0.000
R50.2 Drug-induced fever
0.696 0.304 0.000
R50.1 Persistent fever
0.696 0.304 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.696 0.304 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.696 0.304 0.000
Y59 Other and unspecified vaccines and biological substances
0.696 0.304 0.000
Y58 Bacterial vaccines
0.696 0.304 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.696 0.304 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.696 0.304 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.696 0.304 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.696 0.304 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.696 0.304 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.696 0.304 0.000
Y48 Anaesthetics and therapeutic gases
0.696 0.304 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.696 0.304 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.696 0.304 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.696 0.304 0.000
Y40 Systemic antibiotics
0.696 0.304 0.000
K70.3 Alcoholic cirrhosis of liver
0.695 0.305 0.000
O61 Failed induction of labour
0.695 0.305 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.695 0.305 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.694 0.306 0.000
N99-N99 Other disorders of the genitourinary system
0.693 0.307 0.000
C79.6 Secondary malignant neoplasm of ovary
0.692 0.308 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.692 0.308 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.692 0.308 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.692 0.308 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.691 0.309 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.691 0.309 0.000
F38 Other mood [affective] disorders
0.691 0.309 0.000
F34 Persistent mood [affective] disorders
0.691 0.309 0.000
F30 Manic episode
0.691 0.309 0.000
F39 Unspecified mood [affective] disorder
0.691 0.309 0.000
C77.4 Inguinal and lower limb lymph nodes
0.691 0.309 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.688 0.312 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.688 0.312 0.000
D06 Carcinoma in situ of cervix uteri
0.688 0.312 0.000
C80 Malignant neoplasm without specification of site
0.688 0.312 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.687 0.313 0.000
T40.2 Other opioids
0.687 0.313 0.000
M79.62 Pain in limb (Upper arm)
0.687 0.313 0.000
S62.2 Fracture of first metacarpal bone
0.686 0.314 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.686 0.314 0.000
W19 Unspecified fall
0.686 0.314 0.000
N50 Other disorders of male genital organs
0.686 0.314 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.684 0.316 0.000
C77.2 Intra-abdominal lymph nodes
0.684 0.316 0.000
T78 Adverse effects, not elsewhere classified
0.684 0.316 0.000
F22 Persistent delusional disorders
0.684 0.316 0.000
S64 Injury of nerves at wrist and hand level
0.684 0.316 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.684 0.316 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.684 0.316 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.684 0.316 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.684 0.316 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.684 0.316 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.684 0.316 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.684 0.316 0.000
F11 Mental and behavioural disorders due to use of opioids
0.684 0.316 0.000
T93 Sequelae of injuries of lower limb
0.684 0.316 0.000
I69 Sequelae of cerebrovascular disease
0.684 0.316 0.000
I27 Other pulmonary heart diseases
0.683 0.316 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.683 0.317 0.000
A04.8 Other specified bacterial intestinal infections
0.683 0.317 0.000
Z71.9 Counselling, unspecified
0.683 0.317 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.681 0.319 0.000
M76 Enthesopathies of lower limb, excluding foot
0.681 0.319 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.681 0.319 0.000
M71 Other bursopathies
0.681 0.319 0.000
K70.9 Alcoholic liver disease, unspecified
0.681 0.319 0.000
K80 Cholelithiasis
0.681 0.319 0.000
D55-D59 Haemolytic anaemias
0.680 0.320 0.000
S69 Other and unspecified injuries of wrist and hand
0.679 0.320 0.000
M72 Fibroblastic disorders
0.679 0.321 0.000
I42 Cardiomyopathy
0.678 0.322 0.000
C77.5 Intrapelvic lymph nodes
0.678 0.322 0.000
D46 Myelodysplastic syndromes
0.678 0.322 0.000
K12 Stomatitis and related lesions
0.677 0.323 0.000
L50-L54 Urticaria and erythema
0.674 0.326 0.000
D52.9 Folate deficiency anaemia, unspecified
0.673 0.327 0.000
I35.1 Aortic (valve) insufficiency
0.672 0.328 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.671 0.329 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.671 0.329 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.671 0.329 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.671 0.329 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.671 0.329 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.671 0.329 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.671 0.329 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.671 0.329 0.000
T36 Poisoning by systemic antibiotics
0.671 0.329 0.000
S61 Open wound of wrist and hand
0.671 0.329 0.000
D50.8 Other iron deficiency anaemias
0.671 0.329 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.671 0.329 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.670 0.330 0.000
I99 Other and unspecified disorders of circulatory system
0.669 0.331 0.000
F10.0 Acute intoxication
0.669 0.331 0.000
R47.1 Dysarthria and anarthria
0.669 0.331 0.000
S62.60 Fracture of other finger (closed)
0.669 0.331 0.000
S62.3 Fracture of other metacarpal bone
0.668 0.332 0.000
L10-L14 Bullous disorders
0.668 0.332 0.000
O48 Prolonged pregnancy
0.667 0.333 0.000
R20 Disturbances of skin sensation
0.667 0.333 0.000
D73 Diseases of spleen
0.666 0.334 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.666 0.334 0.000
C73 Malignant neoplasm of thyroid gland
0.666 0.334 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.666 0.334 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.665 0.335 0.000
F32.8 Other depressive episodes
0.664 0.336 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.664 0.336 0.000
F32.1 Moderate depressive episode
0.664 0.336 0.000
F32.0 Mild depressive episode
0.664 0.336 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.663 0.337 0.000
I63.8 Other cerebral infarction
0.662 0.337 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.662 0.337 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.662 0.337 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.662 0.337 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.662 0.337 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.662 0.337 0.000
C77.9 Lymph node, unspecified
0.661 0.339 0.000
Z73 Problems related to life-management difficulty
0.661 0.339 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.661 0.339 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.660 0.340 0.000
S68 Traumatic amputation of wrist and hand
0.659 0.340 0.000
Y57.8 Other drugs and medicaments
0.659 0.341 0.000
Y57.7 Vitamins, not elsewhere classified
0.659 0.341 0.000
Y57.6 Other diagnostic agents
0.659 0.341 0.000
Y57.5 X-ray contrast media
0.659 0.341 0.000
Y57.4 Pharmaceutical excipients
0.659 0.341 0.000
Y57.3 Alcohol deterrents
0.659 0.341 0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified
0.659 0.341 0.000
Y57.1 Lipotropic drugs
0.659 0.341 0.000
Y57.0 Appetite depressants [anorectics]
0.659 0.341 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.658 0.342 0.000
F10.9 Unspecified mental and behavioural disorder
0.658 0.342 0.000
F10.8 Other mental and behavioural disorders
0.658 0.342 0.000
F10.7 Residual and late-onset psychotic disorder
0.658 0.342 0.000
F10.6 Amnesic syndrome
0.658 0.342 0.000
F10.5 Psychotic disorder
0.658 0.342 0.000
F10.4 Withdrawal state with delirium
0.658 0.342 0.000
R23 Other skin changes
0.658 0.342 0.000
E70-E90 Metabolic disorders
0.658 0.342 0.000
R27 Other lack of coordination
0.657 0.343 0.000
H65-H75 Diseases of middle ear and mastoid
0.656 0.344 0.000
K81.1 Chronic cholecystitis
0.656 0.344 0.000
I33 Acute and subacute endocarditis
0.656 0.344 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.656 0.344 0.000
M79.67 Pain in limb (Ankle and foot)
0.656 0.344 0.000
D05 Carcinoma in situ of breast
0.656 0.344 0.000
B25-B34 Other viral diseases
0.655 0.345 0.000
I44.1 Atrioventricular block, second degree
0.655 0.345 0.000
M79.9 Soft tissue disorder, unspecified
0.654 0.345 0.000
M79.5 Residual foreign body in soft tissue
0.654 0.345 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.654 0.345 0.000
M79.3 Panniculitis, unspecified
0.654 0.345 0.000
M79.2 Neuralgia and neuritis, unspecified
0.654 0.345 0.000
M79.1 Myalgia
0.654 0.345 0.000
S65.1 Injury of radial artery at wrist and hand level
0.654 0.346 0.000
I78 Diseases of capillaries
0.654 0.346 0.000
I95 Hypotension
0.654 0.346 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.653 0.347 0.000
D53 Other nutritional anaemias
0.653 0.347 0.000
A07 Other protozoal intestinal diseases
0.652 0.348 0.000
A06 Amoebiasis
0.652 0.348 0.000
A05 Other bacterial foodborne intoxications
0.652 0.348 0.000
A03 Shigellosis
0.652 0.348 0.000
A02 Other Salmonella infections
0.652 0.348 0.000
A01 Typhoid and paratyphoid fevers
0.652 0.348 0.000
A00 Cholera
0.652 0.348 0.000
N25-N29 Other disorders of kidney and ureter
0.651 0.349 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.651 0.349 0.000
K72 Hepatic failure, not elsewhere classified
0.651 0.349 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.650 0.350 0.000
D80-D89 Certain disorders involving the immune mechanism
0.650 0.350 0.000
C78.2 Secondary malignant neoplasm of pleura
0.649 0.351 0.000
R56.8 Other and unspecified convulsions
0.649 0.351 0.000
A41 Other septicaemia
0.649 0.351 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.648 0.351 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.648 0.352 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.647 0.353 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.647 0.353 0.000
O74 Complications of anaesthesia during labour and delivery
0.646 0.353 0.000
O73 Retained placenta and membranes, without haemorrhage
0.646 0.353 0.000
O71 Other obstetric trauma
0.646 0.353 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.646 0.353 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.646 0.353 0.000
O66 Other obstructed labour
0.646 0.353 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.646 0.353 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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