TreeWAS – Variant ID: rs10275663

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XXI Factors influencing health status and contact with health services	0.999	0.001
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.992	0.008
Chapter XI Diseases of the digestive system	0.989	0.011
K55-K64 Other diseases of intestines	0.978	0.022
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.959	0.041
Chapter XX External causes of morbidity and mortality	0.950	0.050
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.948	0.052
K57 Diverticular disease of intestine	0.939	0.061
Z40-Z54 Persons encountering health services for specific procedures and health care	0.938	0.062
K57.3 Diverticular disease of large intestine without perforation or abscess	0.916	0.084
Chapter II Neoplasms	0.916	0.084
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.911	0.089
Z88.0 Personal history of allergy to penicillin	0.908	0.092
Chapter XIV Diseases of the genitourinary system	0.904	0.096
K62 Other diseases of anus and rectum	0.904	0.096
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.883	0.117
Chapter X Diseases of the respiratory system	0.879	0.121
Z00-Z13 Persons encountering health services for examination and investigation	0.868	0.132
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.867	0.133
Z90 Acquired absence of organs, not elsewhere classified	0.863	0.137
Chapter I Certain infectious and parasitic diseases	0.862	0.138
Z86 Personal history of certain other diseases	0.857	0.143
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.848	0.152
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.830	0.170
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.823	0.176
Chapter IX Diseases of the circulatory system	0.823	0.177
R30-R39 Symptoms and signs involving the urinary system	0.821	0.179
D10-D36 Benign neoplasms	0.818	0.182
Z96 Presence of other functional implants	0.808	0.192
K65-K67 Diseases of peritoneum	0.807	0.193
Chapter VI Diseases of the nervous system	0.805	0.195
Z50 Care involving use of rehabilitation procedures	0.804	0.196
K62.8 Other specified diseases of anus and rectum	0.803	0.197
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.799	0.201
Y83.1 Surgical operation with implant of artificial internal device	0.788	0.212
Chapter V Mental and behavioural disorders	0.779	0.221
Z87 Personal history of other diseases and conditions	0.779	0.221
Z88.1 Personal history of allergy to other antibiotic agents	0.777	0.223
Z53 Persons encountering health services for specifie procedures, not carried out	0.777	0.223
K20-K31 Diseases of oesophagus, stomach and duodenum	0.774	0.226
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.774	0.226
Y83.8 Other surgical procedures	0.770	0.230
K59 Other functional intestinal disorders	0.763	0.237
Z92 Personal history of medical treatment	0.758	0.242
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.757	0.243
Chapter XII Diseases of the skin and subcutaneous tissue	0.755	0.245
Z90.7 Acquired absence of genital organ(s)	0.754	0.246
Chapter VIII Diseases of the ear and mastoid process	0.754	0.246
Z86.4 Personal history of psychoactive substance abuse	0.753	0.247
Z45 Adjustment and management of implanted device	0.751	0.249
B95-B98 Bacterial, viral and other infectious agents	0.747	0.253
K62.5 Haemorrhage of anus and rectum	0.746	0.254
N30-N39 Other diseases of urinary system	0.744	0.256
J09-J18 Influenza and pneumonia	0.744	0.256
K63 Other diseases of intestine	0.740	0.260
K90-K93 Other diseases of the digestive system	0.739	0.261
N20-N23 Urolithiasis	0.735	0.265
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.734	0.266
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.733	0.267
N80-N98 Noninflammatory disorders of female genital tract	0.727	0.273
I30-I52 Other forms of heart disease	0.726	0.274
Z95 Presence of cardiac and vascular implants and grafts	0.723	0.277
Z70-Z76 Persons encountering health services in other circumstances	0.722	0.278
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.721	0.279
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.719	0.280
Y83.2 Surgical operation with anastomosis, bypass or graft	0.718	0.282
Z80 Family history of malignant neoplasm	0.718	0.282
Chapter XXII Codes for special purposes	0.717	0.283
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.717	0.283
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.716	0.284
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.711	0.289
Z98 Other postsurgical states	0.711	0.289
Z97 Presence of other devices	0.711	0.289
Z94 Transplanted organ and tissue status	0.711	0.289
Z93 Artificial opening status	0.711	0.289
Z91 Personal history of risk-factors, not elsewhere classified	0.711	0.289
Z89 Acquired absence of limb	0.711	0.289
Z84 Family history of other conditions	0.711	0.289
Z83 Family history of other specific disorders	0.711	0.289
Z81 Family history of mental and behavioural disorders	0.711	0.289
K70-K77 Diseases of liver	0.709	0.291
K35-K38 Diseases of appendix	0.709	0.291
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.709	0.291
Z50.1 Other physical therapy	0.708	0.292
Z88.6 Personal history of allergy to analgesic agent	0.708	0.292
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.707	0.293
Chapter XV Pregnancy, childbirth and the puerperium	0.706	0.294
Y83.6 Removal of other organ (partial) (total)	0.706	0.294
N17-N19 Renal failure	0.705	0.295
W00-W19 Falls	0.705	0.295
Z85 Personal history of malignant neoplasm	0.703	0.297
J90-J94 Other diseases of pleura	0.701	0.299
K64 Haemorrhoids and perianal venous thrombosis	0.701	0.299
K61 Abscess of anal and rectal regions	0.701	0.299
K60 Fissure and fistula of anal and rectal regions	0.701	0.299
K56 Paralytic ileus and intestinal obstruction without hernia	0.701	0.299
K55 Vascular disorders of intestine	0.701	0.299
R15 Faecal incontinence	0.700	0.300
Z47 Other orthopaedic follow-up care	0.699	0.301
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.698	0.301
Chapter IV Endocrine, nutritional and metabolic diseases	0.698	0.302
Z51 Other medical care	0.696	0.304
Z46 Fitting and adjustment of other devices	0.696	0.304
T81 Complications of procedures, not elsewhere classified	0.695	0.305
Z53.8 Procedure not carried out for other reasons	0.695	0.305
C64-C68 Malignant neoplasms of urinary tract	0.694	0.306
R95-R99 Ill-defined and unknown causes of mortality	0.688	0.312
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.688	0.312
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.688	0.312
R47-R49 Symptoms and signs involving speech and voice	0.688	0.312
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.688	0.312
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.688	0.312
Z12 Special screening examination for neoplasms	0.686	0.314
K62.1 Rectal polyp	0.684	0.316
R19 Other symptoms and signs involving the digestive system and abdomen	0.683	0.317
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.681	0.319
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.681	0.319
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.681	0.319
Y60-Y69 Misadventures to patients during surgical and medical care	0.681	0.319
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.681	0.319
Y35-Y36 Legal intervention and operations of war	0.681	0.319
Y10-Y34 Event of undetermined intent	0.681	0.319
Y00-Y09 Assault	0.681	0.319
X85-X99 Assault	0.681	0.319
X60-X84 Intentional self-harm	0.681	0.319
X58-X59 Accidental exposure to other and unspecified factors	0.681	0.319
X50-X57 Overexertion, travel and privation	0.681	0.319
X40-X49 Accidental poisoning by and exposure to noxious substances	0.681	0.319
X30-X39 Exposure to forces of nature	0.681	0.319
X20-X29 Contact with venomous animals and plants	0.681	0.319
X10-X19 Contact with heat and hot substances	0.681	0.319
X00-X09 Exposure to smoke, fire and flames	0.681	0.319
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.681	0.319
W75-W84 Other accidental threats to breathing	0.681	0.319
W65-W74 Accidental drowning and submersion	0.681	0.319
W50-W64 Exposure to animate mechanical forces	0.681	0.319
W20-W49 Exposure to inanimate mechanical forces	0.681	0.319
V98-V99 Other and unspecified transport accidents	0.681	0.319
V95-V97 Air and space transport accidents	0.681	0.319
V90-V94 Water transport accidents	0.681	0.319
V80-V89 Other land transport accidents	0.681	0.319
V70-V79 Bus occupant injured in transport accident	0.681	0.319
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.681	0.319
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.681	0.319
V40-V49 Car occupant injured in transport accident	0.681	0.319
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.681	0.319
V20-V29 Motorcycle rider injured in transport accident	0.681	0.319
V10-V19 Pedal cyclist injured in transport accident	0.681	0.319
V01-V09 Pedestrian injured in transport accident	0.681	0.319
R10 Abdominal and pelvic pain	0.680	0.320
J40-J47 Chronic lower respiratory diseases	0.680	0.320
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.680	0.320
Z88.7 Personal history of allergy to serum and vaccine	0.680	0.320
Z88.5 Personal history of allergy to narcotic agent	0.680	0.320
Z88.4 Personal history of allergy to anaesthetic agent	0.680	0.320
Z88.3 Personal history of allergy to other anti-infective agents	0.680	0.320
Z88.2 Personal history of allergy to sulphonamides	0.680	0.320
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.680	0.320
R33 Retention of urine	0.677	0.323
R07 Pain in throat and chest	0.677	0.323
K66 Other disorders of peritoneum	0.676	0.324
D24 Benign neoplasm of breast	0.675	0.325
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.673	0.326
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.673	0.326
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.673	0.326
K57.2 Diverticular disease of large intestine with perforation and abscess	0.673	0.326
K57.1 Diverticular disease of small intestine without perforation or abscess	0.673	0.326
K57.0 Diverticular disease of small intestine with perforation and abscess	0.673	0.326
Z54 Convalescence	0.673	0.327
Z52 Donors of organs and tissues	0.673	0.327
Z49 Care involving dialysis	0.673	0.327
Z48 Other surgical follow-up care	0.673	0.327
Z44 Fitting and adjustment of external prosthetic device	0.673	0.327
Z43 Attention to artificial openings	0.673	0.327
Z42 Follow-up care involving plastic surgery	0.673	0.327
Z41 Procedures for purposes other than remedying health state	0.673	0.327
Z40 Prophylactic surgery	0.673	0.327
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.671	0.329
K22 Other diseases of oesophagus	0.669	0.331
Z86.0 Personal history of other neoplasms	0.668	0.332
K58 Irritable bowel syndrome	0.667	0.333
R04 Haemorrhage from respiratory passages	0.663	0.337
C43-C44 Melanoma and other malignant neoplasms of skin	0.663	0.337
R31 Unspecified haematuria	0.662	0.338
Z87.1 Personal history of diseases of the digestive system	0.658	0.342
D37-D48 Neoplasms of uncertain or unknown behaviour	0.656	0.343
D00-D09 In situ neoplasms	0.656	0.343
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.656	0.343
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.656	0.343
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.656	0.343
C51-C58 Malignant neoplasms of female genital organs	0.656	0.343
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.656	0.343
C40-C41 Malignant neoplasms of bone and articular cartilage	0.656	0.343
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.656	0.343
C15-C26 Malignant neoplasms of digestive organs	0.656	0.343
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.656	0.343
Z90.4 Acquired absence of other parts of digestive tract	0.656	0.344
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.653	0.347
A00-A09 Intestinal infectious diseases	0.652	0.348
M15-M19 Arthrosis	0.650	0.350
N99-N99 Other disorders of the genitourinary system	0.648	0.352
N70-N77 Inflammatory diseases of female pelvic organs	0.648	0.352
N60-N64 Disorders of breast	0.648	0.352
N25-N29 Other disorders of kidney and ureter	0.648	0.352
N10-N16 Renal tubulo-interstitial diseases	0.648	0.352
N00-N08 Glomerular diseases	0.648	0.352
K62.9 Disease of anus and rectum, unspecified	0.648	0.352
K62.7 Radiation proctitis	0.648	0.352
K62.6 Ulcer of anus and rectum	0.648	0.352
K62.4 Stenosis of anus and rectum	0.648	0.352
K62.3 Rectal prolapse	0.648	0.352
K62.2 Anal prolapse	0.648	0.352
K62.0 Anal polyp	0.648	0.352
Z86.7 Personal history of diseases of the circulatory system	0.648	0.352
R12 Heartburn	0.647	0.353
J18 Pneumonia, organism unspecified	0.647	0.353
Z96.0 Presence of urogenital implants	0.646	0.354
Z08 Follow-up examination after treatment for malignant neoplasm	0.645	0.355
Chapter VII Diseases of the eye and adnexa	0.644	0.355
M50-M54 Other dorsopathies	0.642	0.358
D50-D53 Nutritional anaemias	0.640	0.360
K21 Gastro-oesophageal reflux disease	0.638	0.362
C60-C63 Malignant neoplasms of male genital organs	0.638	0.362
R50-R69 General symptoms and signs	0.637	0.363
J30-J39 Other diseases of upper respiratory tract	0.637	0.363
G40-G47 Episodic and paroxysmal disorders	0.635	0.365
Y83.9 Surgical procedure, unspecified	0.633	0.367
Y83.5 Amputation of limb(s)	0.633	0.367
Y83.4 Other reconstructive surgery	0.633	0.367
Y83.3 Surgical operation with formation of external stoma	0.633	0.367
Y83.0 Surgical operation with transplant of whole organ	0.633	0.367
G35-G37 Demyelinating diseases of the central nervous system	0.631	0.369
J95-J99 Other diseases of the respiratory system	0.630	0.369
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.630	0.369
J80-J84 Other respiratory diseases principally affecting the interstitium	0.630	0.369
J60-J70 Lung diseases due to external agents	0.630	0.369
J00-J06 Acute upper respiratory infections	0.630	0.369
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.628	0.372
Z13 Special screening examination for other diseases and disorders	0.627	0.373
M05-M14 Inflammatory polyarthropathies	0.626	0.374
D22 Melanocytic naevi	0.626	0.374
K50-K52 Noninfective enteritis and colitis	0.626	0.374
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons	0.624	0.376
Z11 Special screening examination for infectious and parasitic diseases	0.622	0.377
Z10 Routine general health check-up of defined subpopulation	0.622	0.377
Z04 Examination and observation for other reasons	0.622	0.377
Z02 Examination and encounter for administrative purposes	0.622	0.377
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.622	0.377
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.622	0.377
Z96.6 Presence of orthopaedic joint implants	0.622	0.378
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.622	0.378
T79-T79 Certain early complications of trauma	0.622	0.378
T66-T78 Other and unspecified effects of external causes	0.622	0.378
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.622	0.378
T36-T50 Poisoning by drugs, medicaments and biological substances	0.622	0.378
T33-T35 Frostbite	0.622	0.378
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.622	0.378
T26-T28 Burns and corrosions confined to eye and internal organs	0.622	0.378
T20-T25 Burns and corrosions of external body surface, specified by site	0.622	0.378
T15-T19 Effects of foreign body entering through natural orifice	0.622	0.378
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.622	0.378
T00-T07 Injuries involving multiple body regions	0.622	0.378
S90-S99 Injuries to the ankle and foot	0.622	0.378
S80-S89 Injuries to the knee and lower leg	0.622	0.378
S70-S79 Injuries to the hip and thigh	0.622	0.378
S60-S69 Injuries to the wrist and hand	0.622	0.378
S40-S49 Injuries to the shoulder and upper arm	0.622	0.378
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.622	0.378
S20-S29 Injuries to the thorax	0.622	0.378
S10-S19 Injuries to the neck	0.622	0.378
S00-S09 Injuries to the head	0.622	0.378
Z90.8 Acquired absence of other organs	0.619	0.381
Z90.6 Acquired absence of other parts of urinary tract	0.619	0.381
Z90.5 Acquired absence of kidney	0.619	0.381
Z90.3 Acquired absence of part of stomach	0.619	0.381
Z90.2 Acquired absence of lung [part of]	0.619	0.381
Z90.1 Acquired absence of breast(s)	0.619	0.381
Z90.0 Acquired absence of part of head and neck	0.619	0.381
B99-B99 Other infectious diseases	0.618	0.382
B90-B94 Sequelae of infectious and parasitic diseases	0.618	0.382
B85-B89 Pediculosis, acariasis and other infestations	0.618	0.382
B65-B83 Helminthiases	0.618	0.382
B50-B64 Protozoal diseases	0.618	0.382
B35-B49 Mycoses	0.618	0.382
B25-B34 Other viral diseases	0.618	0.382
B20-B24 Human immunodeficiency virus [HIV] disease	0.618	0.382
B15-B19 Viral hepatitis	0.618	0.382
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.618	0.382
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.618	0.382
A80-A89 Viral infections of the central nervous system	0.618	0.382
A75-A79 Rickettsioses	0.618	0.382
A70-A74 Other diseases caused by chlamydiae	0.618	0.382
A65-A69 Other spirochaetal diseases	0.618	0.382
A50-A64 Infections with a predominantly sexual mode of transmission	0.618	0.382
A30-A49 Other bacterial diseases	0.618	0.382
A20-A28 Certain zoonotic bacterial diseases	0.618	0.382
A15-A19 Tuberculosis	0.618	0.382
S50-S59 Injuries to the elbow and forearm	0.617	0.383
N39 Other disorders of urinary system	0.617	0.383
Z45.0 Adjustment and management of cardiac pacemaker	0.617	0.383
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.617	0.383
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.615	0.385
I50 Heart failure	0.615	0.385
Z86.5 Personal history of other mental and behavioural disorders	0.614	0.386
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.614	0.386
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.614	0.386
Z86.1 Personal history of infectious and parasitic diseases	0.614	0.386
N20 Calculus of kidney and ureter	0.614	0.386
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.614	0.386
M45-M49 Spondylopathies	0.612	0.388
F30-F39 Mood [affective] disorders	0.611	0.388
K59.0 Constipation	0.610	0.390
Z03 Medical observation and evaluation for suspected diseases and conditions	0.609	0.391
K26 Duodenal ulcer	0.608	0.392
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.608	0.392
R18 Ascites	0.608	0.392
R17 Unspecified jaundice	0.608	0.392
R14 Flatulence and related conditions	0.608	0.392
M20-M25 Other joint disorders	0.606	0.393
Z09.8 Follow-up examination after other treatment for other conditions	0.605	0.395
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.602	0.398
I10-I15 Hypertensive diseases	0.602	0.398
R11 Nausea and vomiting	0.600	0.400
Z92.6 Personal history of chemotherapy for neoplastic disease	0.600	0.400
F40-F48 Neurotic, stress-related and somatoform disorders	0.598	0.402
N84 Polyp of female genital tract	0.598	0.402
R06 Abnormalities of breathing	0.598	0.402
J20-J22 Other acute lower respiratory infections	0.595	0.404
T81.4 Infection following a procedure, not elsewhere classified	0.595	0.405
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.595	0.405
M91-M94 Chondropathies	0.595	0.405
M86-M90 Other osteopathies	0.595	0.405
M65-M68 Disorders of synovium and tendon	0.595	0.405
M60-M63 Disorders of muscles	0.595	0.405
M40-M43 Deforming dorsopathies	0.595	0.405
M00-M03 Infectious arthropathies	0.595	0.405
N40-N51 Diseases of male genital organs	0.595	0.405
D60-D64 Aplastic and other anaemias	0.592	0.408
R00 Abnormalities of heart beat	0.592	0.408
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.590	0.409
R03 Abnormal blood-pressure reading, without diagnosis	0.590	0.409
R01 Cardiac murmurs and other cardiac sounds	0.590	0.409
R05 Cough	0.590	0.409
R02 Gangrene, not elsewhere classified	0.590	0.409
I95-I99 Other and unspecified disorders of the circulatory system	0.590	0.409
I70-I79 Diseases of arteries, arterioles and capillaries	0.590	0.409
I60-I69 Cerebrovascular diseases	0.590	0.409
I05-I09 Chronic rheumatic heart diseases	0.590	0.409
I00-I02 Acute rheumatic fever	0.590	0.409
K80 Cholelithiasis	0.590	0.410
R39 Other symptoms and signs involving the urinary system	0.589	0.411
R30 Pain associated with micturition	0.589	0.411
R36 Urethral discharge	0.589	0.411
R35 Polyuria	0.589	0.411
R34 Anuria and oliguria	0.589	0.411
R32 Unspecified urinary incontinence	0.589	0.411
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.589	0.411
M80-M85 Disorders of bone density and structure	0.588	0.412
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.588	0.412
Z85.4 Personal history of malignant neoplasm of genital organs	0.587	0.413
D25 Leiomyoma of uterus	0.586	0.414
D36 Benign neoplasm of other and unspecified sites	0.586	0.414
D35 Benign neoplasm of other and unspecified endocrine glands	0.586	0.414
D33 Benign neoplasm of brain and other parts of central nervous system	0.586	0.414
D32 Benign neoplasm of meninges	0.586	0.414
D31 Benign neoplasm of eye and adnexa	0.586	0.414
D30 Benign neoplasm of urinary organs	0.586	0.414
D29 Benign neoplasm of male genital organs	0.586	0.414
D28 Benign neoplasm of other and unspecified female genital organs	0.586	0.414
D26 Other benign neoplasms of uterus	0.586	0.414
D23 Other benign neoplasms of skin	0.586	0.414
D21 Other benign neoplasms of connective and other soft tissue	0.586	0.414
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.586	0.414
D19 Benign neoplasm of mesothelial tissue	0.586	0.414
D18 Haemangioma and lymphangioma, any site	0.586	0.414
D17 Benign lipomatous neoplasm	0.586	0.414
D16 Benign neoplasm of bone and articular cartilage	0.586	0.414
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.586	0.414
D14 Benign neoplasm of middle ear and respiratory system	0.586	0.414
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.586	0.414
D11 Benign neoplasm of major salivary glands	0.586	0.414
D10 Benign neoplasm of mouth and pharynx	0.586	0.414
D34 Benign neoplasm of thyroid gland	0.586	0.414
D27 Benign neoplasm of ovary	0.586	0.414
C50-C50 Malignant neoplasm of breast	0.585	0.415
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.584	0.416
K66.0 Peritoneal adhesions	0.582	0.418
Z09.0 Follow-up examination after surgery for other conditions	0.580	0.420
L20-L30 Dermatitis and eczema	0.580	0.420
Z96.9 Presence of functional implant, unspecified	0.579	0.421
Z96.8 Presence of other specified functional implants	0.579	0.421
Z96.7 Presence of other bone and tendon implants	0.579	0.421
Z96.5 Presence of tooth-root and mandibular implants	0.579	0.421
Z96.4 Presence of endocrine implants	0.579	0.421
Z96.3 Presence of artificial larynx	0.579	0.421
Z96.2 Presence of otological and audiological implants	0.579	0.421
Z96.1 Presence of intraocular lens	0.579	0.421
L00-L08 Infections of the skin and subcutaneous tissue	0.579	0.421
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.578	0.421
K65 Peritonitis	0.578	0.421
H90-H95 Other disorders of ear	0.577	0.423
G90-G99 Other disorders of the nervous system	0.577	0.423
G80-G83 Cerebral palsy and other paralytic syndromes	0.577	0.423
G70-G73 Diseases of myoneural junction and muscle	0.577	0.423
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.577	0.423
G30-G32 Other degenerative diseases of the nervous system	0.577	0.423
G20-G26 Extrapyramidal and movement disorders	0.577	0.423
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.577	0.423
G00-G09 Inflammatory diseases of the central nervous system	0.577	0.423
K40-K46 Hernia	0.577	0.423
J18.1 Lobar pneumonia, unspecified	0.577	0.423
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.577	0.423
Z50.8 Care involving use of rehabilitation procedures	0.577	0.423
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.577	0.423
Z50.6 Orthoptic training	0.577	0.423
Z50.5 Speech therapy	0.577	0.423
Z50.4 Psychotherapy, not elsewhere classified	0.577	0.423
Z50.3 Drug rehabilitation	0.577	0.423
Z50.2 Alcohol rehabilitation	0.577	0.423
Z50.0 Cardiac rehabilitation	0.577	0.423
D70-D77 Other diseases of blood and blood-forming organs	0.577	0.423
Z51.2 Other chemotherapy	0.576	0.424
M70-M79 Other soft tissue disorders	0.576	0.424
Z92.3 Personal history of irradiation	0.574	0.426
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.574	0.426
J90 Pleural effusion, not elsewhere classified	0.574	0.426
I34 Nonrheumatic mitral valve disorders	0.573	0.427
K22.1 Ulcer of oesophagus	0.573	0.427
D80-D89 Certain disorders involving the immune mechanism	0.573	0.427
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.573	0.427
D55-D59 Haemolytic anaemias	0.573	0.427
D12.4 Descending colon	0.570	0.430
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.570	0.430
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.569	0.431
K63.5 Polyp of colon	0.569	0.431
N92 Excessive, frequent and irregular menstruation	0.566	0.433
R19.4 Change in bowel habit	0.565	0.435
R10.3 Pain localised to other parts of lower abdomen	0.563	0.437
Z92.1 Personal history of long-term (current) use of anticoagulants	0.561	0.439
N18 Chronic renal failure	0.560	0.440
K92 Other diseases of digestive system	0.560	0.440
G50-G59 Nerve, nerve root and plexus disorders	0.559	0.441
F99-F99 Unspecified mental disorder	0.558	0.441
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.558	0.441
F80-F89 Disorders of psychological development	0.558	0.441
F70-F79 Mental retardation	0.558	0.441
F60-F69 Disorders of adult personality and behaviour	0.558	0.441
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.558	0.441
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.558	0.441
F00-F09 Organic, including symptomatic, mental disorders	0.558	0.441
Z87.8 Personal history of other specified conditions	0.558	0.442
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.558	0.442
Z87.6 Personal history of certain conditions arising in the perinatal period	0.558	0.442
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.558	0.442
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.558	0.442
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.558	0.442
Z87.0 Personal history of diseases of the respiratory system	0.558	0.442
Z95.0 Presence of cardiac pacemaker	0.557	0.443
Z53.9 Procedure not carried out, unspecified reason	0.557	0.443
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure	0.557	0.443
Z95.8 Presence of other cardiac and vascular implants and grafts	0.555	0.445
K28 Gastrojejunal ulcer	0.555	0.445
K27 Peptic ulcer, site unspecified	0.555	0.445
K25 Gastric ulcer	0.555	0.445
K23 Disorders of oesophagus in diseases classified elsewhere	0.555	0.445
Z12.1 Special screening examination for neoplasm of intestinal tract	0.555	0.445
T88 Other complications of surgical and medical care, not elsewhere classified	0.555	0.445
T87 Complications peculiar to reattachment and amputation	0.555	0.445
T86 Failure and rejection of transplanted organs and tissues	0.555	0.445
T85 Complications of other internal prosthetic devices, implants and grafts	0.555	0.445
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.555	0.445
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.555	0.445
T80 Complications following infusion, transfusion and therapeutic injection	0.555	0.445
I44 Atrioventricular and left bundle-branch block	0.554	0.446
I20-I25 Ischaemic heart diseases	0.554	0.446
R91 Abnormal findings on diagnostic imaging of lung	0.551	0.449
N35 Urethral stricture	0.551	0.449
R07.4 Chest pain, unspecified	0.548	0.452
K59.9 Functional intestinal disorder, unspecified	0.547	0.452
K59.8 Other specified functional intestinal disorders	0.547	0.452
K59.4 Anal spasm	0.547	0.452
K59.3 Megacolon, not elsewhere classified	0.547	0.452
K59.2 Neurogenic bowel, not elsewhere classified	0.547	0.452
K59.1 Functional diarrhoea	0.547	0.452
D12.2 Ascending colon	0.546	0.454
E65-E68 Obesity and other hyperalimentation	0.544	0.455
Z92.9 Personal history of medical treatment, unspecified	0.544	0.456
Z92.8 Personal history of other medical treatment	0.544	0.456
Z92.5 Personal history of rehabilitation measures	0.544	0.456
Z92.4 Personal history of major surgery, not elsewhere classified	0.544	0.456
Z92.0 Personal history of contraception	0.544	0.456
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.542	0.457
K86 Other diseases of pancreas	0.542	0.457
K85 Acute pancreatitis	0.542	0.457
K83 Other diseases of biliary tract	0.542	0.457
K82 Other diseases of gallbladder	0.542	0.457
K81 Cholecystitis	0.542	0.457

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations