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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10415889
log Bayes Factor = 20.2782
Chromosome 19   position 17,544,165  (GRCh37) Explore rs10415889 on Ensembl!
Variant rs10415889 is part of Cluster X0093

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.996 0.004 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.993 0.007 0.000
Chapter XIV Diseases of the genitourinary system
0.989 0.011 0.000
Chapter VII Diseases of the eye and adnexa
0.988 0.012 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.984 0.016 0.000
I25.2 Old myocardial infarction
0.984 0.016 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.984 0.016 0.000
M05-M14 Inflammatory polyarthropathies
0.979 0.021 0.000
S00-S09 Injuries to the head
0.979 0.021 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.977 0.023 0.000
I30-I52 Other forms of heart disease
0.975 0.025 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.972 0.028 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.972 0.028 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.971 0.029 0.000
Chapter XX External causes of morbidity and mortality
0.971 0.029 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.968 0.032 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.966 0.034 0.000
F30-F39 Mood [affective] disorders
0.963 0.037 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.961 0.039 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.961 0.039 0.000
N25-N29 Other disorders of kidney and ureter
0.955 0.045 0.000
H25-H28 Disorders of lens
0.951 0.049 0.000
S01 Open wound of head
0.949 0.051 0.000
N30-N39 Other diseases of urinary system
0.949 0.051 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.948 0.052 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.948 0.052 0.000
E65-E68 Obesity and other hyperalimentation
0.946 0.054 0.000
Chapter VIII Diseases of the ear and mastoid process
0.945 0.055 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.943 0.057 0.000
M06 Other rheumatoid arthritis
0.932 0.068 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.931 0.069 0.000
M70-M79 Other soft tissue disorders
0.931 0.069 0.000
E66 Obesity
0.928 0.072 0.000
J95-J99 Other diseases of the respiratory system
0.927 0.073 0.000
H26 Other cataract
0.926 0.074 0.000
L03 Cellulitis
0.925 0.075 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.925 0.075 0.000
I34 Nonrheumatic mitral valve disorders
0.920 0.080 0.000
J09-J18 Influenza and pneumonia
0.919 0.081 0.000
E66.9 Obesity, unspecified
0.919 0.081 0.000
I60-I69 Cerebrovascular diseases
0.915 0.085 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.913 0.087 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.912 0.088 0.000
M50-M54 Other dorsopathies
0.912 0.088 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.909 0.091 0.000
H26.9 Cataract, unspecified
0.907 0.093 0.000
N32 Other disorders of bladder
0.906 0.094 0.000
J86 Pyothorax
0.903 0.097 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.902 0.098 0.000
N40-N51 Diseases of male genital organs
0.902 0.098 0.000
L03.1 Cellulitis of other parts of limb
0.899 0.101 0.000
M20-M25 Other joint disorders
0.899 0.101 0.000
N28.1 Cyst of kidney, acquired
0.898 0.102 0.000
M06.9 Rheumatoid arthritis, unspecified
0.898 0.102 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.897 0.103 0.000
I49 Other cardiac arrhythmias
0.896 0.104 0.000
F31 Bipolar affective disorder
0.890 0.110 0.000
I44 Atrioventricular and left bundle-branch block
0.886 0.114 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.886 0.114 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.884 0.116 0.000
J42 Unspecified chronic bronchitis
0.881 0.119 0.000
M80-M85 Disorders of bone density and structure
0.878 0.122 0.000
W20-W49 Exposure to inanimate mechanical forces
0.877 0.123 0.000
J86.9 Pyothorax without fistula
0.874 0.126 0.000
S90-S99 Injuries to the ankle and foot
0.869 0.131 0.000
M79.8 Other specified soft tissue disorders
0.868 0.132 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.866 0.134 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.863 0.137 0.000
S80-S89 Injuries to the knee and lower leg
0.863 0.137 0.000
Q60-Q64 Congenital malformations of the urinary system
0.860 0.140 0.000
Chapter I Certain infectious and parasitic diseases
0.860 0.140 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.859 0.141 0.000
I25.5 Ischaemic cardiomyopathy
0.858 0.142 0.000
M54 Dorsalgia
0.857 0.143 0.000
S01.9 Open wound of head, part unspecified
0.856 0.144 0.000
E70-E90 Metabolic disorders
0.855 0.145 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.855 0.145 0.000
J98 Other respiratory disorders
0.854 0.146 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.853 0.147 0.000
I24 Other acute ischaemic heart diseases
0.853 0.147 0.000
H65-H75 Diseases of middle ear and mastoid
0.851 0.149 0.000
I34.0 Mitral (valve) insufficiency
0.851 0.149 0.000
L85 Other epidermal thickening
0.851 0.149 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.849 0.151 0.000
S01.2 Open wound of nose
0.847 0.153 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.847 0.153 0.000
N35 Urethral stricture
0.847 0.153 0.000
I73 Other peripheral vascular diseases
0.846 0.154 0.000
H80-H83 Diseases of inner ear
0.843 0.157 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.843 0.157 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.839 0.161 0.000
I45 Other conduction disorders
0.838 0.162 0.000
M23 Internal derangement of knee
0.836 0.164 0.000
I20 Angina pectoris
0.836 0.164 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.830 0.170 0.000
F33 Recurrent depressive disorder
0.828 0.172 0.000
F40 Phobic anxiety disorders
0.825 0.175 0.000
S01.1 Open wound of eyelid and periocular area
0.824 0.176 0.000
F60-F69 Disorders of adult personality and behaviour
0.823 0.177 0.000
J18 Pneumonia, organism unspecified
0.821 0.179 0.000
N45 Orchitis and epididymitis
0.820 0.180 0.000
L08 Other local infections of skin and subcutaneous tissue
0.819 0.181 0.000
L89 Decubitus ulcer
0.819 0.181 0.000
M54.5 Low back pain
0.818 0.182 0.000
T82.1 Mechanical complication of cardiac electronic device
0.817 0.183 0.000
L40-L45 Papulosquamous disorders
0.817 0.183 0.000
I73.9 Peripheral vascular disease, unspecified
0.817 0.183 0.000
S09 Other and unspecified injuries of head
0.816 0.184 0.000
M40-M43 Deforming dorsopathies
0.815 0.185 0.000
N50 Other disorders of male genital organs
0.814 0.186 0.000
M05 Seropositive rheumatoid arthritis
0.813 0.187 0.000
N17-N19 Renal failure
0.813 0.187 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.810 0.190 0.000
N32.9 Bladder disorder, unspecified
0.809 0.191 0.000
J43 Emphysema
0.807 0.193 0.000
M11 Other crystal arthropathies
0.806 0.194 0.000
B95-B98 Bacterial, viral and other infectious agents
0.804 0.196 0.000
M79.6 Pain in limb
0.802 0.198 0.000
F10.2 Dependence syndrome
0.802 0.198 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.801 0.199 0.000
I44.2 Atrioventricular block, complete
0.798 0.202 0.000
E50-E64 Other nutritional deficiencies
0.795 0.204 0.000
I67 Other cerebrovascular diseases
0.793 0.207 0.000
F10.0 Acute intoxication
0.793 0.207 0.000
H30-H36 Disorders of choroid and retina
0.790 0.210 0.000
S50-S59 Injuries to the elbow and forearm
0.789 0.211 0.000
I20.0 Unstable angina
0.788 0.212 0.000
J18.1 Lobar pneumonia, unspecified
0.787 0.213 0.000
L03.3 Cellulitis of trunk
0.787 0.213 0.000
M23.3 Other meniscus derangements
0.786 0.214 0.000
N39 Other disorders of urinary system
0.785 0.215 0.000
I46 Cardiac arrest
0.785 0.215 0.000
F43 Reaction to severe stress, and adjustment disorders
0.783 0.216 0.000
Q61 Cystic kidney disease
0.783 0.217 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.782 0.218 0.000
F10.3 Withdrawal state
0.780 0.220 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.780 0.220 0.000
E20-E35 Disorders of other endocrine glands
0.779 0.221 0.000
S40-S49 Injuries to the shoulder and upper arm
0.779 0.221 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.777 0.223 0.000
I77 Other disorders of arteries and arterioles
0.776 0.224 0.000
F17.1 Harmful use
0.775 0.225 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.775 0.225 0.000
Chapter VI Diseases of the nervous system
0.775 0.225 0.000
N35.9 Urethral stricture, unspecified
0.774 0.226 0.000
T82.3 Mechanical complication of other vascular grafts
0.773 0.227 0.000
F40.2 Specific (isolated) phobias
0.773 0.227 0.000
W44 Foreign body entering into or through eye or natural orifice
0.773 0.227 0.000
W00-W19 Falls
0.773 0.227 0.000
Chapter XXII Codes for special purposes
0.772 0.228 0.000
M84 Disorders of continuity of bone
0.771 0.229 0.000
X60-X84 Intentional self-harm
0.770 0.230 0.000
I37 Pulmonary valve disorders
0.770 0.230 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.770 0.230 0.000
N32.3 Diverticulum of bladder
0.770 0.230 0.000
V80-V89 Other land transport accidents
0.769 0.231 0.000
I34.1 Mitral (valve) prolapse
0.768 0.232 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.767 0.233 0.000
L81 Other disorders of pigmentation
0.766 0.234 0.000
F32 Depressive episode
0.766 0.234 0.000
J98.4 Other disorders of lung
0.764 0.236 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.763 0.237 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.763 0.237 0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess
0.762 0.238 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.762 0.238 0.000
I63 Cerebral infarction
0.760 0.240 0.000
M13 Other arthritis
0.760 0.240 0.000
S00 Superficial injury of head
0.760 0.240 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.760 0.240 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.759 0.241 0.000
S01.7 Multiple open wounds of head
0.759 0.241 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.758 0.241 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.758 0.242 0.000
I60 Subarachnoid haemorrhage
0.757 0.243 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.755 0.245 0.000
I49.9 Cardiac arrhythmia, unspecified
0.755 0.245 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.754 0.245 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.753 0.247 0.000
S80 Superficial injury of lower leg
0.753 0.247 0.000
I70 Atherosclerosis
0.752 0.248 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.752 0.248 0.000
N28.0 Ischaemia and infarction of kidney
0.752 0.248 0.000
L85.9 Epidermal thickening, unspecified
0.751 0.249 0.000
V20-V29 Motorcycle rider injured in transport accident
0.750 0.250 0.000
J60-J70 Lung diseases due to external agents
0.750 0.250 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.749 0.251 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.749 0.251 0.000
H60-H62 Diseases of external ear
0.748 0.252 0.000
F99-F99 Unspecified mental disorder
0.747 0.253 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.747 0.253 0.000
T90 Sequelae of injuries of head
0.746 0.254 0.000
J46 Status asthmaticus
0.746 0.254 0.000
M79.67 Pain in limb (Ankle and foot)
0.745 0.255 0.000
I38 Endocarditis, valve unspecified
0.744 0.256 0.000
Y85 Sequelae of transport accidents
0.742 0.257 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.742 0.258 0.000
Q00-Q07 Congenital malformations of the nervous system
0.740 0.260 0.000
N26 Unspecified contracted kidney
0.739 0.260 0.000
I67.9 Cerebrovascular disease, unspecified
0.739 0.261 0.000
I49.3 Ventricular premature depolarisation
0.739 0.261 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.739 0.261 0.000
T18 Foreign body in alimentary tract
0.738 0.262 0.000
N41 Inflammatory diseases of prostate
0.738 0.262 0.000
I25.3 Aneurysm of heart
0.738 0.262 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.738 0.262 0.000
F17.2 Dependence syndrome
0.737 0.263 0.000
T79-T79 Certain early complications of trauma
0.737 0.263 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.736 0.264 0.000
L03.2 Cellulitis of face
0.735 0.264 0.000
B35-B49 Mycoses
0.735 0.265 0.000
M91-M94 Chondropathies
0.735 0.265 0.000
I44.0 Atrioventricular block, first degree
0.735 0.265 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.735 0.265 0.000
N60-N64 Disorders of breast
0.734 0.266 0.000
H02 Other disorders of eyelid
0.734 0.266 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.734 0.266 0.000
L93 Lupus erythematosus
0.733 0.266 0.000
J00-J06 Acute upper respiratory infections
0.733 0.267 0.000
Q80-Q89 Other congenital malformations
0.733 0.267 0.000
H53-H54 Visual disturbances and blindness
0.732 0.268 0.000
T66-T78 Other and unspecified effects of external causes
0.731 0.269 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.731 0.269 0.000
F31.9 Bipolar affective disorder, unspecified
0.731 0.269 0.000
I49.8 Other specified cardiac arrhythmias
0.730 0.270 0.000
H83 Other diseases of inner ear
0.730 0.270 0.000
H04 Disorders of lachrymal system
0.730 0.270 0.000
H26.1 Traumatic cataract
0.730 0.270 0.000
E78.5 Hyperlipidaemia, unspecified
0.730 0.270 0.000
N50.1 Vascular disorders of male genital organs
0.729 0.271 0.000
I42 Cardiomyopathy
0.729 0.271 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.727 0.273 0.000
S10-S19 Injuries to the neck
0.726 0.273 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.725 0.275 0.000
N48 Other disorders of penis
0.724 0.276 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.724 0.276 0.000
L05 Pilonidal cyst
0.723 0.277 0.000
N32.1 Vesicointestinal fistula
0.723 0.277 0.000
M54.50 Low back pain (Multiple sites in spine)
0.723 0.277 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.722 0.278 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.721 0.279 0.000
H26.2 Complicated cataract
0.720 0.280 0.000
H35 Other retinal disorders
0.719 0.281 0.000
M86-M90 Other osteopathies
0.719 0.281 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.718 0.282 0.000
J98.1 Pulmonary collapse
0.718 0.282 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F80-F89 Disorders of psychological development
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.716 0.284 0.000
L10-L14 Bullous disorders
0.714 0.286 0.000
N34 Urethritis and urethral syndrome
0.714 0.286 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.714 0.286 0.000
H20 Iridocyclitis
0.712 0.288 0.000
M50 Cervical disk disorders
0.712 0.288 0.000
S01.3 Open wound of ear
0.712 0.288 0.000
T87 Complications peculiar to reattachment and amputation
0.712 0.288 0.000
T86 Failure and rejection of transplanted organs and tissues
0.712 0.288 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.712 0.288 0.000
M10 Gout
0.709 0.291 0.000
M79.0 Rheumatism, unspecified
0.709 0.291 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.708 0.292 0.000
M65-M68 Disorders of synovium and tendon
0.707 0.292 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.707 0.293 0.000
Q50-Q56 Congenital malformations of genital organs
0.707 0.293 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.707 0.293 0.000
I62 Other nontraumatic intracranial haemorrhage
0.707 0.293 0.000
G90-G99 Other disorders of the nervous system
0.706 0.294 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.706 0.294 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.705 0.294 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.705 0.294 0.000
L94 Other localised connective tissue disorders
0.705 0.294 0.000
L87 Transepidermal elimination disorders
0.705 0.294 0.000
L88 Pyoderma gangrenosum
0.705 0.294 0.000
L86 Keratoderma in diseases classified elsewhere
0.705 0.294 0.000
L83 Acanthosis nigricans
0.705 0.294 0.000
L80 Vitiligo
0.705 0.294 0.000
S02 Fracture of skull and facial bones
0.705 0.295 0.000
I22 Subsequent myocardial infarction
0.703 0.297 0.000
M14 Arthropathies in other diseases classified elsewhere
0.702 0.298 0.000
M12 Other specific arthropathies
0.702 0.298 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.702 0.298 0.000
M08 Juvenile arthritis
0.702 0.298 0.000
S08 Traumatic amputation of part of head
0.702 0.298 0.000
S07 Crushing injury of head
0.702 0.298 0.000
S05 Injury of eye and orbit
0.702 0.298 0.000
S04 Injury of cranial nerves
0.702 0.298 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.702 0.298 0.000
H55-H59 Other disorders of eye and adnexa
0.701 0.299 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.701 0.299 0.000
I49.0 Ventricular fibrillation and flutter
0.700 0.300 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.700 0.300 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.700 0.300 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.700 0.300 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.700 0.300 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.700 0.300 0.000
I52 Other heart disorders in diseases classified elsewhere
0.699 0.301 0.000
I48 Atrial fibrillation and flutter
0.699 0.301 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.699 0.301 0.000
I41 Myocarditis in diseases classified elsewhere
0.699 0.301 0.000
I40 Acute myocarditis
0.699 0.301 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.699 0.301 0.000
I36 Nonrheumatic tricuspid valve disorders
0.699 0.301 0.000
I33 Acute and subacute endocarditis
0.699 0.301 0.000
I32 Pericarditis in diseases classified elsewhere
0.699 0.301 0.000
I30 Acute pericarditis
0.699 0.301 0.000
W44.0 Home
0.699 0.301 0.000
S09.9 Unspecified injury of head
0.699 0.301 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.698 0.302 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.698 0.302 0.000
F60 Specific personality disorders
0.697 0.302 0.000
H02.8 Other specified disorders of eyelid
0.697 0.303 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.697 0.303 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.697 0.303 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.697 0.303 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.697 0.303 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.697 0.303 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.697 0.303 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.697 0.303 0.000
F11 Mental and behavioural disorders due to use of opioids
0.697 0.303 0.000
E40-E46 Malnutrition
0.696 0.304 0.000
Y35-Y36 Legal intervention and operations of war
0.696 0.304 0.000
Y10-Y34 Event of undetermined intent
0.696 0.304 0.000
Y00-Y09 Assault
0.696 0.304 0.000
X85-X99 Assault
0.696 0.304 0.000
X50-X57 Overexertion, travel and privation
0.696 0.304 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.696 0.304 0.000
X30-X39 Exposure to forces of nature
0.696 0.304 0.000
X20-X29 Contact with venomous animals and plants
0.696 0.304 0.000
X10-X19 Contact with heat and hot substances
0.696 0.304 0.000
X00-X09 Exposure to smoke, fire and flames
0.696 0.304 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.696 0.304 0.000
W75-W84 Other accidental threats to breathing
0.696 0.304 0.000
W65-W74 Accidental drowning and submersion
0.696 0.304 0.000
W50-W64 Exposure to animate mechanical forces
0.696 0.304 0.000
V98-V99 Other and unspecified transport accidents
0.696 0.304 0.000
V95-V97 Air and space transport accidents
0.696 0.304 0.000
V90-V94 Water transport accidents
0.696 0.304 0.000
V70-V79 Bus occupant injured in transport accident
0.696 0.304 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.696 0.304 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.696 0.304 0.000
V40-V49 Car occupant injured in transport accident
0.696 0.304 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.696 0.304 0.000
V01-V09 Pedestrian injured in transport accident
0.696 0.304 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.696 0.304 0.000
W22 Striking against or struck by other objects
0.695 0.305 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.695 0.305 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.694 0.306 0.000
H10-H13 Disorders of conjunctiva
0.694 0.306 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.694 0.306 0.000
Q35-Q37 Cleft lip and cleft palate
0.694 0.306 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.694 0.306 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.694 0.306 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.694 0.306 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.694 0.306 0.000
M85 Other disorders of bone density and structure
0.693 0.307 0.000
S92 Fracture of foot, except ankle
0.692 0.308 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.691 0.309 0.000
M07 Psoriatic and enteropathic arthropathies
0.691 0.309 0.000
I61 Intracerebral haemorrhage
0.690 0.310 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.690 0.310 0.000
F38 Other mood [affective] disorders
0.690 0.310 0.000
F34 Persistent mood [affective] disorders
0.690 0.310 0.000
F30 Manic episode
0.690 0.310 0.000
F39 Unspecified mood [affective] disorder
0.690 0.310 0.000
H26.8 Other specified cataract
0.689 0.311 0.000
S01.8 Open wound of other parts of head
0.689 0.311 0.000
L04 Acute lymphadenitis
0.689 0.311 0.000
L01 Impetigo
0.689 0.311 0.000
L00 Staphylococcal scalded skin syndrome
0.689 0.311 0.000
N17 Acute renal failure
0.688 0.312 0.000
N32.0 Bladder-neck obstruction
0.687 0.313 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.686 0.314 0.000
H73 Other disorders of tympanic membrane
0.685 0.315 0.000
J10 Influenza due to identified influenza virus
0.685 0.315 0.000
N18 Chronic renal failure
0.685 0.315 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.685 0.315 0.000
N27 Small kidney of unknown cause
0.685 0.315 0.000
N25 Disorders resulting from impaired renal tubular function
0.685 0.315 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.685 0.315 0.000
H65 Nonsuppurative otitis media
0.684 0.316 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.683 0.317 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.683 0.317 0.000
S32 Fracture of lumbar spine and pelvis
0.683 0.317 0.000
H43-H45 Disorders of vitreous body and globe
0.683 0.317 0.000
M11.2 Other chondrocalcinosis
0.682 0.318 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.682 0.318 0.000
H27 Other disorders of lens
0.682 0.318 0.000
I69 Sequelae of cerebrovascular disease
0.682 0.318 0.000
L43 Lichen planus
0.681 0.319 0.000
H66 Suppurative and unspecified otitis media
0.681 0.319 0.000
I46.0 Cardiac arrest with successful resuscitation
0.681 0.319 0.000
J20-J22 Other acute lower respiratory infections
0.681 0.319 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.681 0.319 0.000
S01.4 Open wound of cheek and temporomandibular area
0.681 0.319 0.000
N37 Urethral disorders in diseases classified elsewhere
0.680 0.320 0.000
N33 Bladder disorders in diseases classified elsewhere
0.680 0.320 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.680 0.320 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.680 0.320 0.000
H00 Hordeolum and chalazion
0.680 0.320 0.000
E53 Deficiency of other B group vitamins
0.680 0.320 0.000
E88 Other metabolic disorders
0.679 0.321 0.000
E67 Other hyperalimentation
0.678 0.322 0.000
E68 Sequelae of hyperalimentation
0.678 0.322 0.000
E65 Localised adiposity
0.678 0.322 0.000
M22 Disorders of patella
0.677 0.323 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.677 0.323 0.000
Y85.0 Sequelae of motor-vehicle accident
0.677 0.323 0.000
M81 Osteoporosis without pathological fracture
0.677 0.323 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.677 0.323 0.000
J85 Abscess of lung and mediastinum
0.676 0.323 0.000
N39.4 Other specified urinary incontinence
0.675 0.325 0.000
M24 Other specific joint derangements
0.674 0.326 0.000
N36 Other disorders of urethra
0.674 0.326 0.000
Q61.2 Polycystic kidney, adult type
0.674 0.326 0.000
V10-V19 Pedal cyclist injured in transport accident
0.674 0.326 0.000
S90 Superficial injury of ankle and foot
0.673 0.327 0.000
S91 Open wound of ankle and foot
0.673 0.327 0.000
S80.8 Other superficial injuries of lower leg
0.673 0.327 0.000
D50-D53 Nutritional anaemias
0.673 0.327 0.000
Q43 Other congenital malformations of intestine
0.672 0.328 0.000
S06 Intracranial injury
0.672 0.328 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.671 0.329 0.000
M34 Systemic sclerosis
0.670 0.330 0.000
I45.6 Preexcitation syndrome
0.670 0.330 0.000
Q61.3 Polycystic kidney, unspecified
0.670 0.330 0.000
H80 Otosclerosis
0.670 0.330 0.000
Q44.6 Cystic disease of liver
0.669 0.331 0.000
J43.9 Emphysema, unspecified
0.669 0.331 0.000
I83 Varicose veins of lower extremities
0.669 0.331 0.000
N41.9 Inflammatory disease of prostate, unspecified
0.669 0.331 0.000
H25 Senile cataract
0.669 0.331 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.669 0.331 0.000
M06.8 Other specified rheumatoid arthritis
0.668 0.332 0.000
M06.4 Inflammatory polyarthropathy
0.668 0.332 0.000
M06.3 Rheumatoid nodule
0.668 0.332 0.000
M06.2 Rheumatoid bursitis
0.668 0.332 0.000
M06.1 Adult-onset Still's disease
0.668 0.332 0.000
M06.0 Seronegative rheumatoid arthritis
0.668 0.332 0.000
M76 Enthesopathies of lower limb, excluding foot
0.667 0.332 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.667 0.332 0.000
M71 Other bursopathies
0.667 0.332 0.000
N00-N08 Glomerular diseases
0.666 0.334 0.000
T91 Sequelae of injuries of neck and trunk
0.665 0.335 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.665 0.335 0.000
E66.1 Drug-induced obesity
0.665 0.335 0.000
E66.0 Obesity due to excess calories
0.665 0.335 0.000
F42 Obsessive-compulsive disorder
0.665 0.335 0.000
I49.1 Atrial premature depolarisation
0.665 0.335 0.000
J96 Respiratory failure, not elsewhere classified
0.664 0.335 0.000
H26.3 Drug-induced cataract
0.664 0.336 0.000
H26.0 Infantile, juvenile and presenile cataract
0.664 0.336 0.000
S99 Other and unspecified injuries of ankle and foot
0.664 0.336 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.663 0.337 0.000
I44.1 Atrioventricular block, second degree
0.663 0.337 0.000
I72 Other aneurysm
0.661 0.339 0.000
M21 Other acquired deformities of limbs
0.661 0.339 0.000
T18.1 Foreign body in oesophagus
0.660 0.340 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.659 0.340 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.660 0.340 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.659 0.341 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.659 0.341 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.659 0.341 0.000
J17 Pneumonia in diseases classified elsewhere
0.659 0.341 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.659 0.341 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.659 0.341 0.000
J12 Viral pneumonia, not elsewhere classified
0.659 0.341 0.000
J11 Influenza, virus not identified
0.659 0.341 0.000
J14 Pneumonia due to Haemophilus influenzae
0.659 0.341 0.000
J09 Influenza due to certain identified influenza virus
0.659 0.341 0.000
W29 Contact with other powered hand tools and household machinery
0.659 0.341 0.000
M43 Other deforming dorsopathies
0.659 0.341 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.659 0.341 0.000
I45.2 Bifascicular block
0.658 0.342 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.657 0.343 0.000
H21 Other disorders of iris and ciliary body
0.657 0.343 0.000
L03.8 Cellulitis of other sites
0.656 0.344 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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