TreeWAS – Variant ID: rs10480

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
I60-I69 Cerebrovascular diseases	0.999	0.001
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002
Chapter IX Diseases of the circulatory system	0.997	0.003
Chapter X Diseases of the respiratory system	0.996	0.004
S00-S09 Injuries to the head	0.995	0.005
Chapter VI Diseases of the nervous system	0.995	0.005
J80-J84 Other respiratory diseases principally affecting the interstitium	0.985	0.015
S09 Other and unspecified injuries of head	0.983	0.017
I63 Cerebral infarction	0.982	0.018
Chapter XI Diseases of the digestive system	0.982	0.018
I67 Other cerebrovascular diseases	0.976	0.024
M50-M54 Other dorsopathies	0.972	0.028
S09.9 Unspecified injury of head	0.972	0.028
I69 Sequelae of cerebrovascular disease	0.969	0.031
M54 Dorsalgia	0.967	0.033
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.965	0.035
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.961	0.039
M20-M25 Other joint disorders	0.960	0.040
Chapter XX External causes of morbidity and mortality	0.960	0.040
K90-K93 Other diseases of the digestive system	0.960	0.040
K70-K77 Diseases of liver	0.956	0.044
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.952	0.048
J30-J39 Other diseases of upper respiratory tract	0.951	0.049
G90-G99 Other disorders of the nervous system	0.950	0.050
I63.9 Cerebral infarction, unspecified	0.945	0.055
M54.9 Dorsalgia, unspecified	0.942	0.058
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.939	0.061
J84 Other interstitial pulmonary diseases	0.936	0.064
K70 Alcoholic liver disease	0.935	0.065
K92 Other diseases of digestive system	0.930	0.070
M05-M14 Inflammatory polyarthropathies	0.928	0.072
M22 Disorders of patella	0.927	0.073
M54.99 Dorsalgia, unspecified (Site unspecified)	0.919	0.081
Chapter I Certain infectious and parasitic diseases	0.917	0.083
Chapter IV Endocrine, nutritional and metabolic diseases	0.916	0.084
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.911	0.089
G40-G47 Episodic and paroxysmal disorders	0.911	0.089
I67.9 Cerebrovascular disease, unspecified	0.904	0.096
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.899	0.101
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.896	0.104
G80-G83 Cerebral palsy and other paralytic syndromes	0.894	0.106
I61 Intracerebral haemorrhage	0.888	0.112
M22.4 Chondromalacia patellae	0.887	0.113
Chapter II Neoplasms	0.887	0.113
M23 Internal derangement of knee	0.885	0.115
M54.5 Low back pain	0.884	0.116
Chapter XII Diseases of the skin and subcutaneous tissue	0.884	0.116
K92.2 Gastro-intestinal haemorrhage, unspecified	0.883	0.117
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.881	0.119
D70-D77 Other diseases of blood and blood-forming organs	0.878	0.122
M86-M90 Other osteopathies	0.877	0.123
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.875	0.125
J32 Chronic sinusitis	0.875	0.125
J34 Other disorders of nose and nasal sinuses	0.874	0.126
C79 Secondary malignant neoplasm of other sites	0.874	0.126
G30-G32 Other degenerative diseases of the nervous system	0.872	0.127
J84.9 Interstitial pulmonary disease, unspecified	0.872	0.128
J33 Nasal polyp	0.870	0.130
G91 Hydrocephalus	0.865	0.135
M06 Other rheumatoid arthritis	0.864	0.136
I67.2 Cerebral atherosclerosis	0.860	0.140
J81 Pulmonary oedema	0.860	0.140
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.856	0.144
M54.56 Low back pain (Lumbar region)	0.855	0.145
K92.0 Haematemesis	0.855	0.145
S70-S79 Injuries to the hip and thigh	0.854	0.146
J80 Adult respiratory distress syndrome	0.852	0.148
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.851	0.149
J95-J99 Other diseases of the respiratory system	0.850	0.150
Chapter V Mental and behavioural disorders	0.843	0.157
M23.8 Other internal derangements of knee	0.841	0.159
Q80-Q89 Other congenital malformations	0.839	0.161
L80-L99 Other disorders of the skin and subcutaneous tissue	0.839	0.161
M54.2 Cervicalgia	0.837	0.163
E70-E90 Metabolic disorders	0.836	0.164
K70.4 Alcoholic hepatic failure	0.836	0.164
L20-L30 Dermatitis and eczema	0.835	0.165
S10-S19 Injuries to the neck	0.835	0.165
K90 Intestinal malabsorption	0.834	0.166
A30-A49 Other bacterial diseases	0.834	0.166
I69.3 Sequelae of cerebral infarction	0.834	0.166
T84.0 Mechanical complication of internal joint prosthesis	0.834	0.166
K70.3 Alcoholic cirrhosis of liver	0.831	0.169
I65.2 Occlusion and stenosis of carotid artery	0.828	0.172
G47 Sleep disorders	0.827	0.173
I67.8 Other specified cerebrovascular diseases	0.827	0.173
D00-D09 In situ neoplasms	0.825	0.175
K65-K67 Diseases of peritoneum	0.825	0.175
S01 Open wound of head	0.824	0.176
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.821	0.179
W00-W19 Falls	0.818	0.182
Q60-Q64 Congenital malformations of the urinary system	0.816	0.184
M80-M85 Disorders of bone density and structure	0.814	0.186
M06.9 Rheumatoid arthritis, unspecified	0.814	0.186
G81 Hemiplegia	0.813	0.187
K70.1 Alcoholic hepatitis	0.812	0.188
M34 Systemic sclerosis	0.812	0.188
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.809	0.191
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.809	0.191
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.809	0.191
K50-K52 Noninfective enteritis and colitis	0.809	0.191
T90 Sequelae of injuries of head	0.807	0.193
Y60-Y69 Misadventures to patients during surgical and medical care	0.806	0.194
I69.0 Sequelae of subarachnoid haemorrhage	0.806	0.194
S06 Intracranial injury	0.806	0.194
J34.8 Other specified disorders of nose and nasal sinuses	0.805	0.195
K76 Other diseases of liver	0.803	0.197
B95-B98 Bacterial, viral and other infectious agents	0.800	0.200
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.800	0.200
Chapter VIII Diseases of the ear and mastoid process	0.799	0.201
S02 Fracture of skull and facial bones	0.798	0.202
G95 Other diseases of spinal cord	0.795	0.205
W20-W49 Exposure to inanimate mechanical forces	0.795	0.205
I95-I99 Other and unspecified disorders of the circulatory system	0.795	0.205
M60-M63 Disorders of muscles	0.793	0.207
M22.8 Other disorders of patella	0.793	0.207
T84.1 Mechanical complication of internal fixation device of bones of limb	0.791	0.209
G91.9 Hydrocephalus, unspecified	0.790	0.210
M91-M94 Chondropathies	0.790	0.210
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.789	0.211
I70-I79 Diseases of arteries, arterioles and capillaries	0.788	0.212
T84.2 Mechanical complication of internal fixation device of other bones	0.788	0.212
J09-J18 Influenza and pneumonia	0.786	0.214
I64 Stroke, not specified as haemorrhage or infarction	0.786	0.214
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.784	0.216
D80-D89 Certain disorders involving the immune mechanism	0.783	0.217
S00 Superficial injury of head	0.782	0.218
J40-J47 Chronic lower respiratory diseases	0.782	0.218
Y86 Sequelae of other accidents	0.781	0.219
K40-K46 Hernia	0.779	0.221
J82 Pulmonary eosinophilia, not elsewhere classified	0.778	0.221
G90 Disorders of autonomic nervous system	0.778	0.222
J60-J70 Lung diseases due to external agents	0.778	0.222
L27 Dermatitis due to substances taken internally	0.777	0.223
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.774	0.226
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.771	0.229
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.770	0.230
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.770	0.230
S09.8 Other specified injuries of head	0.767	0.233
L89 Decubitus ulcer	0.767	0.233
T85 Complications of other internal prosthetic devices, implants and grafts	0.766	0.234
M54.6 Pain in thoracic spine	0.766	0.234
D70 Agranulocytosis	0.766	0.234
S05 Injury of eye and orbit	0.765	0.235
T91 Sequelae of injuries of neck and trunk	0.765	0.235
M53 Other dorsopathies, not elsewhere classified	0.764	0.236
J33.0 Polyp of nasal cavity	0.761	0.239
A41 Other septicaemia	0.759	0.241
G47.3 Sleep apnoea	0.757	0.243
J37 Chronic laryngitis and laryngotracheitis	0.756	0.243
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.756	0.244
D75 Other diseases of blood and blood-forming organs	0.754	0.246
J84.8 Other specified interstitial pulmonary diseases	0.752	0.248
E80 Disorders of porphyrin and bilirubin metabolism	0.752	0.248
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.751	0.249
S80-S89 Injuries to the knee and lower leg	0.751	0.249
J32.9 Chronic sinusitis, unspecified	0.750	0.250
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.749	0.251
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.747	0.253
V80-V89 Other land transport accidents	0.746	0.254
M54.22 Cervicalgia (Cervical region)	0.743	0.257
Chapter XXII Codes for special purposes	0.742	0.258
J32.2 Chronic ethmoidal sinusitis	0.742	0.258
I61.9 Intracerebral haemorrhage, unspecified	0.741	0.258
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.741	0.259
C79.8 Secondary malignant neoplasm of other specified sites	0.741	0.259
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.739	0.261
Q50-Q56 Congenital malformations of genital organs	0.739	0.261
B99-B99 Other infectious diseases	0.738	0.262
M21 Other acquired deformities of limbs	0.736	0.263
L27.0 Generalised skin eruption due to drugs and medicaments	0.735	0.265
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.735	0.265
M11 Other crystal arthropathies	0.735	0.265
I60 Subarachnoid haemorrhage	0.733	0.267
G31.9 Degenerative disease of nervous system, unspecified	0.733	0.267
H90-H95 Other disorders of ear	0.733	0.267
S01.8 Open wound of other parts of head	0.733	0.267
I63.8 Other cerebral infarction	0.731	0.269
D60-D64 Aplastic and other anaemias	0.729	0.271
E00-E07 Disorders of thyroid gland	0.728	0.272
T86 Failure and rejection of transplanted organs and tissues	0.727	0.272
M35 Other systemic involvement of connective tissue	0.727	0.273
Q20-Q28 Congenital malformations of the circulatory system	0.726	0.274
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.726	0.274
M86 Osteomyelitis	0.723	0.277
F00-F09 Organic, including symptomatic, mental disorders	0.723	0.277
M54.55 Low back pain (Thoracolumbar region)	0.723	0.277
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.723	0.277
T15-T19 Effects of foreign body entering through natural orifice	0.721	0.278
J84.1 Other interstitial pulmonary diseases with fibrosis	0.721	0.279
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.721	0.279
Q61 Cystic kidney disease	0.721	0.279
D50-D53 Nutritional anaemias	0.721	0.279
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.720	0.280
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.719	0.281
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.719	0.281
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.718	0.282
K43 Ventral hernia	0.718	0.282
G00-G09 Inflammatory diseases of the central nervous system	0.717	0.283
G81.9 Hemiplegia, unspecified	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I68 Cerebrovascular disorders in diseases classified elsewhere	0.716	0.284
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.716	0.284
M00-M03 Infectious arthropathies	0.716	0.284
T33-T35 Frostbite	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
J40 Bronchitis, not specified as acute or chronic	0.716	0.284
K72 Hepatic failure, not elsewhere classified	0.715	0.284
I00-I02 Acute rheumatic fever	0.715	0.285
J33.8 Other polyp of sinus	0.714	0.286
S08 Traumatic amputation of part of head	0.714	0.286
S07 Crushing injury of head	0.714	0.286
S04 Injury of cranial nerves	0.714	0.286
S03 Dislocation, sprain and strain of joints and ligaments of head	0.714	0.286
M90 Osteopathies in diseases classified elsewhere	0.712	0.288
G70-G73 Diseases of myoneural junction and muscle	0.711	0.289
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.710	0.290
K04 Diseases of pulp and periapical tissues	0.710	0.290
J44 Other chronic obstructive pulmonary disease	0.709	0.291
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.709	0.291
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.709	0.291
T79-T79 Certain early complications of trauma	0.709	0.291
L92 Granulomatous disorders of skin and subcutaneous tissue	0.708	0.292
M07 Psoriatic and enteropathic arthropathies	0.708	0.292
S79 Other and unspecified injuries of hip and thigh	0.708	0.292
M24 Other specific joint derangements	0.708	0.292
K70.9 Alcoholic liver disease, unspecified	0.707	0.292
M65-M68 Disorders of synovium and tendon	0.707	0.293
I67.1 Cerebral aneurysm, nonruptured	0.707	0.293
J34.0 Abscess, furuncle and carbuncle of nose	0.706	0.294
S09.7 Multiple injuries of head	0.705	0.295
S09.2 Traumatic rupture of ear drum	0.705	0.295
S09.1 Injury of muscle and tendon of head	0.705	0.295
S09.0 Injury of blood vessels of head, not elsewhere classified	0.705	0.295
Q00-Q07 Congenital malformations of the nervous system	0.704	0.296
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.704	0.296
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.704	0.296
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.704	0.296
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.704	0.296
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.704	0.296
T94 Sequelae of injuries involving multiple and unspecified body regions	0.703	0.297
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.702	0.297
T92 Sequelae of injuries of upper limb	0.702	0.298
C79.7 Secondary malignant neoplasm of adrenal gland	0.702	0.298
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.701	0.299
K52 Other non-infective gastro-enteritis and colitis	0.701	0.299
E87 Other disorders of fluid, electrolyte and acid-base balance	0.700	0.300
I67.7 Cerebral arteritis, not elsewhere classified	0.700	0.300
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.700	0.300
I67.5 Moyamoya disease	0.700	0.300
I67.4 Hypertensive encephalopathy	0.700	0.300
I67.3 Progressive vascular leukoencephalopathy	0.700	0.300
I67.0 Dissection of cerebral arteries, nonruptured	0.700	0.300
G35-G37 Demyelinating diseases of the central nervous system	0.699	0.301
L91 Hypertrophic disorders of skin	0.699	0.301
D55-D59 Haemolytic anaemias	0.697	0.302
T66-T78 Other and unspecified effects of external causes	0.697	0.303
G41 Status epilepticus	0.697	0.303
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.696	0.304
J99 Respiratory disorders in diseases classified elsewhere	0.696	0.304
T84.3 Mechanical complication of other bone devices, implants and grafts	0.696	0.304
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.695	0.305
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.695	0.305
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.695	0.305
I69.1 Sequelae of intracerebral haemorrhage	0.695	0.305
M54.8 Other dorsalgia	0.693	0.307
M54.0 Panniculitis affecting regions of neck and back	0.693	0.307
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.693	0.307
L90 Atrophic disorders of skin	0.693	0.307
W18 Other fall on same level	0.693	0.307
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.692	0.308
D37-D48 Neoplasms of uncertain or unknown behaviour	0.692	0.308
G31.2 Degeneration of nervous system due to alcohol	0.691	0.309
E80.4 Gilbert's syndrome	0.691	0.309
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.691	0.309
K92.1 Melaena	0.691	0.309
E87.6 Hypokalaemia	0.690	0.310
C77.0 Lymph nodes of head, face and neck	0.690	0.310
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.689	0.311
Q35-Q37 Cleft lip and cleft palate	0.689	0.311
Q30-Q34 Congenital malformations of the respiratory system	0.689	0.311
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.689	0.311
M33 Dermatopolymyositis	0.689	0.311
M32 Systemic lupus erythematosus	0.689	0.311
M30 Polyarteritis nodosa and related conditions	0.689	0.311
G45 Transient cerebral ischaemic attacks and related syndromes	0.689	0.311
Y35-Y36 Legal intervention and operations of war	0.688	0.311
Y10-Y34 Event of undetermined intent	0.688	0.311
Y00-Y09 Assault	0.688	0.311
X85-X99 Assault	0.688	0.311
X58-X59 Accidental exposure to other and unspecified factors	0.688	0.311
X50-X57 Overexertion, travel and privation	0.688	0.311
X30-X39 Exposure to forces of nature	0.688	0.311
X20-X29 Contact with venomous animals and plants	0.688	0.311
X10-X19 Contact with heat and hot substances	0.688	0.311
X00-X09 Exposure to smoke, fire and flames	0.688	0.311
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.688	0.311
W75-W84 Other accidental threats to breathing	0.688	0.311
W65-W74 Accidental drowning and submersion	0.688	0.311
W50-W64 Exposure to animate mechanical forces	0.688	0.311
V98-V99 Other and unspecified transport accidents	0.688	0.311
V95-V97 Air and space transport accidents	0.688	0.311
V90-V94 Water transport accidents	0.688	0.311
V70-V79 Bus occupant injured in transport accident	0.688	0.311
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.688	0.311
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.688	0.311
V40-V49 Car occupant injured in transport accident	0.688	0.311
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.688	0.311
V01-V09 Pedestrian injured in transport accident	0.688	0.311
K93 Disorders of other digestive organs in diseases classified elsewhere	0.688	0.311
J39 Other diseases of upper respiratory tract	0.688	0.312
M87 Osteonecrosis	0.686	0.314
E10-E14 Diabetes mellitus	0.686	0.314
J15 Bacterial pneumonia, not elsewhere classified	0.686	0.314
K77 Liver disorders in diseases classified elsewhere	0.685	0.314
K73 Chronic hepatitis, not elsewhere classified	0.685	0.314
K71 Toxic liver disease	0.685	0.314
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.685	0.315
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.685	0.315
K65 Peritonitis	0.684	0.316
S00.8 Superficial injury of other parts of head	0.684	0.316
T87 Complications peculiar to reattachment and amputation	0.682	0.318
T80 Complications following infusion, transfusion and therapeutic injection	0.682	0.318
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.682	0.318
J30 Vasomotor and allergic rhinitis	0.681	0.319
G94 Other disorders of brain in diseases classified elsewhere	0.681	0.319
G98 Other disorders of nervous system, not elsewhere classified	0.681	0.319
G92 Toxic encephalopathy	0.681	0.319
J98 Other respiratory disorders	0.681	0.319
K08 Other disorders of teeth and supporting structures	0.681	0.319
R41 Other symptoms and signs involving cognitive functions and awareness	0.681	0.319
H91 Other hearing loss	0.681	0.319
K90.0 Coeliac disease	0.680	0.320
F05 Delirium, not induced by alcohol and other psychoactive substances	0.680	0.320
A80-A89 Viral infections of the central nervous system	0.679	0.321
D04 Carcinoma in situ of skin	0.679	0.321
L30 Other dermatitis	0.679	0.321
C79.6 Secondary malignant neoplasm of ovary	0.679	0.321
D07 Carcinoma in situ of other and unspecified genital organs	0.679	0.321
I78 Diseases of capillaries	0.678	0.322
D69 Purpura and other haemorrhagic conditions	0.678	0.322
J32.0 Chronic maxillary sinusitis	0.678	0.322
G44 Other headache syndromes	0.677	0.323
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.677	0.323
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.676	0.324
C80 Malignant neoplasm without specification of site	0.676	0.324
G43 Migraine	0.676	0.324
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.675	0.324
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.675	0.324
M54.94 Dorsalgia, unspecified (Thoracic region)	0.675	0.324
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.675	0.324
M54.92 Dorsalgia, unspecified (Cervical region)	0.675	0.324
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.675	0.324
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.675	0.324
G97.8 Other postprocedural disorders of nervous system	0.674	0.326
G81.1 Spastic hemiplegia	0.674	0.326
D73 Diseases of spleen	0.674	0.326
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.673	0.327
D06 Carcinoma in situ of cervix uteri	0.673	0.327
M34.1 CR(E)ST syndrome	0.672	0.327
G82 Paraplegia and tetraplegia	0.672	0.328
J84.0 Alveolar and parietoalveolar conditions	0.671	0.329
K70.2 Alcoholic fibrosis and sclerosis of liver	0.670	0.330
K70.0 Alcoholic fatty liver	0.670	0.330
M84 Disorders of continuity of bone	0.670	0.330
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.670	0.330
L89.1 Stage II decubitus ulcer	0.670	0.330
K10 Other diseases of jaws	0.669	0.331
K43.9 Ventral hernia without obstruction or gangrene	0.669	0.331
I73 Other peripheral vascular diseases	0.669	0.331
M54.3 Sciatica	0.668	0.332
E20-E35 Disorders of other endocrine glands	0.668	0.332
K74 Fibrosis and cirrhosis of liver	0.668	0.332
S01.2 Open wound of nose	0.668	0.332
W22 Striking against or struck by other objects	0.667	0.332
K92.8 Other specified diseases of digestive system	0.667	0.333
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.667	0.333
G91.1 Obstructive hydrocephalus	0.667	0.333
J33.9 Nasal polyp, unspecified	0.666	0.334
G95.9 Disease of spinal cord, unspecified	0.666	0.334
J35 Chronic diseases of tonsils and adenoids	0.666	0.334
M15-M19 Arthrosis	0.666	0.334
M14 Arthropathies in other diseases classified elsewhere	0.665	0.335
M12 Other specific arthropathies	0.665	0.335
M09 Juvenile arthritis in diseases classified elsewhere	0.665	0.335
M08 Juvenile arthritis	0.665	0.335
S90-S99 Injuries to the ankle and foot	0.665	0.335
A49 Bacterial infection of unspecified site	0.665	0.335
Q85 Phakomatoses, not elsewhere classified	0.665	0.335
M22.1 Recurrent subluxation of patella	0.664	0.335
M22.9 Disorder of patella, unspecified	0.664	0.335
M22.3 Other derangements of patella	0.664	0.335
M22.0 Recurrent dislocation of patella	0.664	0.335
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.663	0.337
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.663	0.337
S02.6 Fracture of mandible	0.662	0.338
X40-X49 Accidental poisoning by and exposure to noxious substances	0.660	0.340
G62 Other polyneuropathies	0.659	0.341
G93 Other disorders of brain	0.658	0.342
F40-F48 Neurotic, stress-related and somatoform disorders	0.658	0.342
V20-V29 Motorcycle rider injured in transport accident	0.658	0.342
K00 Disorders of tooth development and eruption	0.658	0.342
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.657	0.342
B90-B94 Sequelae of infectious and parasitic diseases	0.657	0.343
B85-B89 Pediculosis, acariasis and other infestations	0.657	0.343
B65-B83 Helminthiases	0.657	0.343
B50-B64 Protozoal diseases	0.657	0.343
B20-B24 Human immunodeficiency virus [HIV] disease	0.657	0.343
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.657	0.343
A75-A79 Rickettsioses	0.657	0.343
A70-A74 Other diseases caused by chlamydiae	0.657	0.343
A65-A69 Other spirochaetal diseases	0.657	0.343
A20-A28 Certain zoonotic bacterial diseases	0.657	0.343
A15-A19 Tuberculosis	0.657	0.343
F52 Sexual dysfunction, not caused by organic disorder or disease	0.657	0.343
Q61.0 Congenital single renal cyst	0.657	0.343
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.657	0.343
E86 Volume depletion	0.657	0.343
S72 Fracture of femur	0.656	0.343
Q38-Q45 Other congenital malformations of the digestive system	0.656	0.344
Q89 Other congenital malformations, not elsewhere classified	0.656	0.344
G90.0 Idiopathic peripheral autonomic neuropathy	0.655	0.345
M80 Osteoporosis with pathological fracture	0.655	0.345
M13 Other arthritis	0.654	0.346
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.654	0.346
M54.4 Lumbago with sciatica	0.654	0.346
T98 Sequelae of other and unspecified effects of external causes	0.653	0.346
T95 Sequelae of burns, corrosions and frostbite	0.653	0.346
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.653	0.346
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.653	0.346
G46 Vascular syndromes of brain in cerebrovascular diseases	0.653	0.347
W19 Unspecified fall	0.653	0.347
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.652	0.348
B25-B34 Other viral diseases	0.652	0.348
K04.5 Chronic apical periodontitis	0.652	0.348
L29 Pruritus	0.651	0.349
Q82 Other congenital malformations of skin	0.651	0.349
T90.5 Sequelae of intracranial injury	0.650	0.350
M23.5 Chronic instability of knee	0.649	0.350
A41.8 Other specified septicaemia	0.649	0.351
T90.9 Sequelae of unspecified injury of head	0.649	0.351
F05.9 Delirium, unspecified	0.649	0.351
C51-C58 Malignant neoplasms of female genital organs	0.649	0.351
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.648	0.352
X60-X84 Intentional self-harm	0.648	0.352
T90.2 Sequelae of fracture of skull and facial bones	0.648	0.352
Y43 Primarily systemic agents	0.648	0.352
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.646	0.354
M62 Other disorders of muscle	0.646	0.354
M54.50 Low back pain (Multiple sites in spine)	0.646	0.354
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.646	0.354
M54.96 Dorsalgia, unspecified (Lumbar region)	0.645	0.355
M06.0 Seronegative rheumatoid arthritis	0.645	0.355
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.645	0.355
I65.8 Occlusion and stenosis of other precerebral artery	0.645	0.355
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.645	0.355
I65.1 Occlusion and stenosis of basilar artery	0.645	0.355
I65.0 Occlusion and stenosis of vertebral artery	0.645	0.355
M40-M43 Deforming dorsopathies	0.644	0.355
H91.9 Hearing loss, unspecified	0.643	0.357
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.643	0.357
S70 Superficial injury of hip and thigh	0.643	0.357
D03 Melanoma in situ	0.643	0.357
J34.3 Hypertrophy of nasal turbinates	0.643	0.357
R44 Other symptoms and signs involving general sensations and perceptions	0.643	0.357
E40-E46 Malnutrition	0.642	0.357
S40-S49 Injuries to the shoulder and upper arm	0.642	0.358
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.642	0.358
M93 Other osteochondropathies	0.641	0.359
G80 Infantile cerebral palsy	0.641	0.359
K76.0 Fatty (change of) liver, not elsewhere classified	0.641	0.359
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.640	0.360
K09 Cysts of oral region, not elsewhere classified	0.639	0.360
K76.7 Hepatorenal syndrome	0.639	0.361
K66 Other disorders of peritoneum	0.638	0.362
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.638	0.362
K12 Stomatitis and related lesions	0.637	0.363
G96 Other disorders of central nervous system	0.637	0.363
I61.8 Other intracerebral haemorrhage	0.637	0.363
I61.6 Intracerebral haemorrhage, multiple localised	0.637	0.363
I61.5 Intracerebral haemorrhage, intraventricular	0.637	0.363
I61.4 Intracerebral haemorrhage in cerebellum	0.637	0.363
I61.3 Intracerebral haemorrhage in brain stem	0.637	0.363
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.637	0.363
K90.9 Intestinal malabsorption, unspecified	0.636	0.364
A50-A64 Infections with a predominantly sexual mode of transmission	0.636	0.364
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.636	0.364
C40-C41 Malignant neoplasms of bone and articular cartilage	0.636	0.364
M34.9 Systemic sclerosis, unspecified	0.636	0.364
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.636	0.364
S19 Other and unspecified injuries of neck	0.635	0.365
J69 Pneumonitis due to solids and liquids	0.635	0.365
B15-B19 Viral hepatitis	0.635	0.365
M23.9 Internal derangement of knee, unspecified	0.635	0.365
M23.6 Other spontaneous disruption of ligament(s) of knee	0.635	0.365
M23.1 Discoid meniscus (congenital)	0.635	0.365

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations