TreeWAS – Variant ID: rs10998466

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	0.979	0.021	0.000
Chapter II Neoplasms	0.964	0.036	0.000
Chapter VII Diseases of the eye and adnexa	0.961	0.039	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.958	0.042	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.953	0.047	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.929	0.071	0.000
Chapter XI Diseases of the digestive system	0.921	0.079	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.913	0.087	0.000
Chapter XIV Diseases of the genitourinary system	0.910	0.090	0.000
O60-O75 Complications of labour and delivery	0.909	0.091	0.000
D10-D36 Benign neoplasms	0.909	0.091	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.909	0.091	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.907	0.093	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.902	0.098	0.000
C50-C50 Malignant neoplasm of breast	0.897	0.103	0.000
K86 Other diseases of pancreas	0.880	0.120	0.000
E00-E07 Disorders of thyroid gland	0.876	0.124	0.000
Chapter VIII Diseases of the ear and mastoid process	0.869	0.131	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.869	0.131	0.000
C51-C58 Malignant neoplasms of female genital organs	0.856	0.144	0.000
O00-O08 Pregnancy with abortive outcome	0.855	0.145	0.000
C50 Malignant neoplasm of breast	0.849	0.151	0.000
K13 Other diseases of lip and oral mucosa	0.845	0.155	0.000
Chapter V Mental and behavioural disorders	0.839	0.161	0.000
O70 Perineal laceration during delivery	0.838	0.161	0.000
K80 Cholelithiasis	0.836	0.164	0.000
D25 Leiomyoma of uterus	0.834	0.166	0.000
D17 Benign lipomatous neoplasm	0.833	0.167	0.000
N80-N98 Noninflammatory disorders of female genital tract	0.831	0.169	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.831	0.169	0.000
H04 Disorders of lachrymal system	0.830	0.170	0.000
S60-S69 Injuries to the wrist and hand	0.830	0.170	0.000
N60-N64 Disorders of breast	0.820	0.180	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.812	0.188	0.000
E04 Other non-toxic goitre	0.812	0.188	0.000
Chapter XX External causes of morbidity and mortality	0.812	0.188	0.000
N80 Endometriosis	0.811	0.189	0.000
K08 Other disorders of teeth and supporting structures	0.810	0.190	0.000
D00-D09 In situ neoplasms	0.810	0.190	0.000
D27 Benign neoplasm of ovary	0.798	0.202	0.000
K86.1 Other chronic pancreatitis	0.795	0.205	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.795	0.205	0.000
H25-H28 Disorders of lens	0.795	0.205	0.000
S80-S89 Injuries to the knee and lower leg	0.794	0.206	0.000
O02 Other abnormal products of conception	0.788	0.212	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.787	0.213	0.000
T42.4 Benzodiazepines	0.786	0.214	0.000
H53-H54 Visual disturbances and blindness	0.782	0.218	0.000
O70.0 First degree perineal laceration during delivery	0.779	0.221	0.000
K13.0 Diseases of lips	0.778	0.222	0.000
E04.2 Non-toxic multinodular goitre	0.769	0.231	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.767	0.233	0.000
H02 Other disorders of eyelid	0.767	0.233	0.000
F30-F39 Mood [affective] disorders	0.766	0.234	0.000
D34 Benign neoplasm of thyroid gland	0.765	0.234	0.000
K14 Diseases of tongue	0.760	0.240	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.759	0.241	0.000
O63 Long labour	0.757	0.243	0.000
N00-N08 Glomerular diseases	0.756	0.243	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.751	0.249	0.000
H04.2 Epiphora	0.751	0.249	0.000
K08.3 Retained dental root	0.751	0.249	0.000
K85 Acute pancreatitis	0.745	0.255	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.745	0.255	0.000
N17-N19 Renal failure	0.745	0.255	0.000
N80.9 Endometriosis, unspecified	0.742	0.258	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.742	0.258	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.742	0.258	0.000
O02.1 Missed abortion	0.740	0.260	0.000
K10 Other diseases of jaws	0.739	0.261	0.000
H25 Senile cataract	0.739	0.261	0.000
H55-H59 Other disorders of eye and adnexa	0.737	0.263	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.735	0.265	0.000
K07 Dentofacial anomalies [including malocclusion]	0.735	0.265	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.734	0.266	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.733	0.267	0.000
H65-H75 Diseases of middle ear and mastoid	0.733	0.267	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.730	0.269	0.000
K80.2 Calculus of gallbladder without cholecystitis	0.730	0.270	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.728	0.271	0.000
E10-E14 Diabetes mellitus	0.728	0.272	0.000
C56 Malignant neoplasm of ovary	0.728	0.272	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.727	0.273	0.000
D25.1 Intramural leiomyoma of uterus	0.726	0.274	0.000
C50.3 Lower-inner quadrant of breast	0.725	0.275	0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.723	0.277	0.000
K86.3 Pseudocyst of pancreas	0.722	0.278	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.720	0.280	0.000
N80.0 Endometriosis of uterus	0.720	0.280	0.000
C53 Malignant neoplasm of cervix uteri	0.719	0.281	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.715	0.285	0.000
T66-T78 Other and unspecified effects of external causes	0.714	0.286	0.000
N95 Menopausal and other perimenopausal disorders	0.714	0.286	0.000
N60 Benign mammary dysplasia	0.713	0.287	0.000
K86.8 Other specified diseases of pancreas	0.713	0.287	0.000
N87 Dysplasia of cervix uteri	0.712	0.288	0.000
N20-N23 Urolithiasis	0.711	0.289	0.000
H52 Disorders of refraction and accommodation	0.710	0.290	0.000
E16 Other disorders of pancreatic internal secretion	0.710	0.290	0.000
S70-S79 Injuries to the hip and thigh	0.709	0.291	0.000
Chapter XXII Codes for special purposes	0.709	0.291	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.707	0.293	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.707	0.293	0.000
H43-H45 Disorders of vitreous body and globe	0.705	0.294	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.704	0.296	0.000
N81 Female genital prolapse	0.703	0.297	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.702	0.298	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.702	0.298	0.000
C50.5 Lower-outer quadrant of breast	0.701	0.299	0.000
F32 Depressive episode	0.700	0.300	0.000
D10 Benign neoplasm of mouth and pharynx	0.700	0.300	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.698	0.302	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.697	0.303	0.000
C50.9 Breast, unspecified	0.696	0.304	0.000
C50.8 Overlapping lesion of breast	0.695	0.305	0.000
H90-H95 Other disorders of ear	0.695	0.305	0.000
H60-H62 Diseases of external ear	0.693	0.307	0.000
E03 Other hypothyroidism	0.692	0.308	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.691	0.309	0.000
S50-S59 Injuries to the elbow and forearm	0.691	0.309	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.691	0.309	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.691	0.309	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.691	0.309	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.691	0.309	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.691	0.309	0.000
C79 Secondary malignant neoplasm of other sites	0.690	0.310	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.690	0.310	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.689	0.311	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.689	0.311	0.000
H10-H13 Disorders of conjunctiva	0.689	0.311	0.000
T79-T79 Certain early complications of trauma	0.687	0.313	0.000
T33-T35 Frostbite	0.687	0.313	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.687	0.313	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.687	0.313	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.687	0.313	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.687	0.313	0.000
T00-T07 Injuries involving multiple body regions	0.687	0.313	0.000
S10-S19 Injuries to the neck	0.687	0.313	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.687	0.313	0.000
O72 Postpartum haemorrhage	0.686	0.314	0.000
S90-S99 Injuries to the ankle and foot	0.686	0.314	0.000
N64 Other disorders of breast	0.686	0.314	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.685	0.315	0.000
H25.0 Senile incipient cataract	0.685	0.315	0.000
O66 Other obstructed labour	0.685	0.315	0.000
O85-O92 Complications predominantly related to the puerperium	0.683	0.317	0.000
H25.8 Other senile cataract	0.681	0.319	0.000
D25.2 Subserosal leiomyoma of uterus	0.680	0.320	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.678	0.322	0.000
D25.0 Submucous leiomyoma of uterus	0.673	0.327	0.000
E07 Other disorders of thyroid	0.671	0.328	0.000
N99-N99 Other disorders of the genitourinary system	0.671	0.329	0.000
H30-H36 Disorders of choroid and retina	0.670	0.330	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.669	0.331	0.000
H04.1 Other disorders of lachrymal gland	0.669	0.331	0.000
S40-S49 Injuries to the shoulder and upper arm	0.667	0.333	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.666	0.333	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.666	0.334	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.666	0.334	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.666	0.334	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.666	0.334	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.666	0.334	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.666	0.334	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.666	0.334	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.666	0.334	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.666	0.334	0.000
T36 Poisoning by systemic antibiotics	0.666	0.334	0.000
H00 Hordeolum and chalazion	0.665	0.335	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.664	0.336	0.000
N62 Hypertrophy of breast	0.664	0.336	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.664	0.336	0.000
X60-X84 Intentional self-harm	0.663	0.337	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.663	0.337	0.000
K70-K77 Diseases of liver	0.662	0.338	0.000
K14.8 Other diseases of tongue	0.659	0.341	0.000
Chapter IX Diseases of the circulatory system	0.658	0.342	0.000
N18 Chronic renal failure	0.657	0.343	0.000
S20-S29 Injuries to the thorax	0.656	0.344	0.000
N94.6 Dysmenorrhoea, unspecified	0.656	0.344	0.000
H01 Other inflammation of eyelid	0.655	0.345	0.000
E40-E46 Malnutrition	0.655	0.345	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.654	0.346	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.654	0.346	0.000
H53 Visual disturbances	0.653	0.347	0.000
O74 Complications of anaesthesia during labour and delivery	0.652	0.348	0.000
O73 Retained placenta and membranes, without haemorrhage	0.652	0.348	0.000
O71 Other obstetric trauma	0.652	0.348	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.652	0.348	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.652	0.348	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.652	0.348	0.000
O62 Abnormalities of forces of labour	0.652	0.348	0.000
O61 Failed induction of labour	0.652	0.348	0.000
O60 Preterm delivery	0.652	0.348	0.000
S64 Injury of nerves at wrist and hand level	0.652	0.348	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.652	0.348	0.000
D31 Benign neoplasm of eye and adnexa	0.651	0.348	0.000
D30 Benign neoplasm of urinary organs	0.651	0.348	0.000
D29 Benign neoplasm of male genital organs	0.651	0.348	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.651	0.348	0.000
D26 Other benign neoplasms of uterus	0.651	0.348	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.651	0.348	0.000
D19 Benign neoplasm of mesothelial tissue	0.651	0.348	0.000
D16 Benign neoplasm of bone and articular cartilage	0.651	0.348	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.651	0.348	0.000
D11 Benign neoplasm of major salivary glands	0.651	0.348	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.651	0.349	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.650	0.350	0.000
H05 Disorders of orbit	0.650	0.350	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.650	0.350	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.650	0.350	0.000
E16.2 Hypoglycaemia, unspecified	0.649	0.351	0.000
E10 Insulin-dependent diabetes mellitus	0.649	0.351	0.000
K12 Stomatitis and related lesions	0.647	0.353	0.000
K09 Cysts of oral region, not elsewhere classified	0.647	0.353	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.647	0.353	0.000
K03 Other diseases of hard tissues of teeth	0.647	0.353	0.000
K00 Disorders of tooth development and eruption	0.647	0.353	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.646	0.354	0.000
N80.3 Endometriosis of pelvic peritoneum	0.645	0.355	0.000
N80.2 Endometriosis of Fallopian tube	0.644	0.356	0.000
O03 Spontaneous abortion	0.642	0.358	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.641	0.359	0.000
K83 Other diseases of biliary tract	0.638	0.362	0.000
O70.1 Second degree perineal laceration during delivery	0.637	0.363	0.000
C80 Malignant neoplasm without specification of site	0.635	0.364	0.000
N84 Polyp of female genital tract	0.635	0.365	0.000
F60-F69 Disorders of adult personality and behaviour	0.635	0.365	0.000
D32 Benign neoplasm of meninges	0.633	0.367	0.000
O48 Prolonged pregnancy	0.632	0.368	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.631	0.369	0.000
K86.9 Disease of pancreas, unspecified	0.631	0.369	0.000
K86.2 Cyst of pancreas	0.631	0.369	0.000
D18 Haemangioma and lymphangioma, any site	0.629	0.371	0.000
D03 Melanoma in situ	0.629	0.371	0.000
E06 Thyroiditis	0.628	0.372	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.628	0.372	0.000
E00 Congenital iodine-deficiency syndrome	0.628	0.372	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.628	0.372	0.000
K02 Dental caries	0.626	0.374	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.626	0.374	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.626	0.374	0.000
K11 Diseases of salivary glands	0.623	0.376	0.000
O63.1 Prolonged second stage (of labour)	0.623	0.377	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.623	0.377	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.623	0.377	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.623	0.377	0.000
T42.3 Barbiturates	0.623	0.377	0.000
T42.2 Succinimides and oxazolidinediones	0.623	0.377	0.000
T42.1 Iminostilbenes	0.623	0.377	0.000
T42.0 Hydantoin derivatives	0.623	0.377	0.000
K10.8 Other specified diseases of jaws	0.623	0.377	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.623	0.377	0.000
H02.0 Entropion and trichiasis of eyelid	0.622	0.378	0.000
S61 Open wound of wrist and hand	0.622	0.378	0.000
N23 Unspecified renal colic	0.622	0.378	0.000
C53.9 Cervix uteri, unspecified	0.621	0.379	0.000
N95.0 Postmenopausal bleeding	0.620	0.380	0.000
C50.2 Upper-inner quadrant of breast	0.619	0.381	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.618	0.381	0.000
F31 Bipolar affective disorder	0.616	0.384	0.000
N81.5 Vaginal enterocele	0.616	0.384	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.616	0.384	0.000
K07.6 Temporomandibular joint disorders	0.615	0.385	0.000
N87.1 Moderate cervical dysplasia	0.615	0.385	0.000
H52.1 Myopia	0.614	0.386	0.000
K65-K67 Diseases of peritoneum	0.614	0.386	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.614	0.386	0.000
C51 Malignant neoplasm of vulva	0.614	0.386	0.000
C58 Malignant neoplasm of placenta	0.614	0.386	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.614	0.386	0.000
C52 Malignant neoplasm of vagina	0.614	0.386	0.000
K80.4 Calculus of bile duct with cholecystitis	0.613	0.387	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.613	0.387	0.000
O07 Failed attempted abortion	0.613	0.387	0.000
O06 Unspecified abortion	0.613	0.387	0.000
O05 Other abortion	0.613	0.387	0.000
O01 Hydatidiform mole	0.613	0.387	0.000
O00 Ectopic pregnancy	0.613	0.387	0.000
E50-E64 Other nutritional deficiencies	0.613	0.387	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.613	0.387	0.000
D36 Benign neoplasm of other and unspecified sites	0.612	0.387	0.000
C77.3 Axillary and upper limb lymph nodes	0.611	0.389	0.000
H02.3 Blepharochalasis	0.610	0.390	0.000
E20-E35 Disorders of other endocrine glands	0.609	0.391	0.000
T45.0 Antiallergic and antiemetic drugs	0.609	0.391	0.000
C50.6 Axillary tail of breast	0.609	0.391	0.000
C50.1 Central portion of breast	0.609	0.391	0.000
C50.0 Nipple and areola	0.609	0.391	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.608	0.392	0.000
N25-N29 Other disorders of kidney and ureter	0.607	0.393	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.606	0.394	0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.606	0.394	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.606	0.394	0.000
K13.5 Oral submucous fibrosis	0.606	0.394	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.606	0.394	0.000
K13.3 Hairy leukoplakia	0.606	0.394	0.000
K13.1 Cheek and lip biting	0.606	0.394	0.000
N85 Other noninflammatory disorders of uterus, except cervix	0.605	0.395	0.000
C77.2 Intra-abdominal lymph nodes	0.605	0.395	0.000
S81 Open wound of lower leg	0.604	0.396	0.000
D09 Carcinoma in situ of other and unspecified sites	0.604	0.396	0.000
S62 Fracture at wrist and hand level	0.603	0.397	0.000
N81.2 Incomplete uterovaginal prolapse	0.603	0.397	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.602	0.398	0.000
F99-F99 Unspecified mental disorder	0.601	0.398	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.601	0.398	0.000
F80-F89 Disorders of psychological development	0.601	0.398	0.000
F70-F79 Mental retardation	0.601	0.398	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.601	0.398	0.000
O70.9 Perineal laceration during delivery, unspecified	0.601	0.399	0.000
O70.3 Fourth degree perineal laceration during delivery	0.601	0.399	0.000
O70.2 Third degree perineal laceration during delivery	0.601	0.399	0.000
S00-S09 Injuries to the head	0.601	0.399	0.000
F32.9 Depressive episode, unspecified	0.600	0.400	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.600	0.400	0.000
K80.3 Calculus of bile duct with cholangitis	0.600	0.400	0.000
K80.8 Other cholelithiasis	0.600	0.400	0.000
E04.9 Non-toxic goitre, unspecified	0.599	0.401	0.000
O42 Premature rupture of membranes	0.599	0.401	0.000
K85.1 Biliary acute pancreatitis	0.598	0.402	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.598	0.402	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.597	0.403	0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.597	0.403	0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.597	0.403	0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.597	0.403	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.597	0.403	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.597	0.403	0.000
H02.4 Ptosis of eyelid	0.596	0.404	0.000
H65 Nonsuppurative otitis media	0.596	0.404	0.000
N98 Complications associated with artificial fertilisation	0.596	0.404	0.000
N91 Absent, scanty and rare menstruation	0.596	0.404	0.000
N82 Fistulae involving female genital tract	0.596	0.404	0.000
N96 Habitual aborter	0.596	0.404	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.595	0.404	0.000
H40-H42 Glaucoma	0.595	0.404	0.000
C54 Malignant neoplasm of corpus uteri	0.595	0.405	0.000
H04.9 Disorder of lachrymal system, unspecified	0.595	0.405	0.000
H04.8 Other disorders of lachrymal system	0.595	0.405	0.000
H04.6 Other changes in lachrymal passages	0.595	0.405	0.000
H04.4 Chronic inflammation of lachrymal passages	0.595	0.405	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.595	0.405	0.000
H04.0 Dacryoadenitis	0.595	0.405	0.000
N10-N16 Renal tubulo-interstitial diseases	0.595	0.405	0.000
S69 Other and unspecified injuries of wrist and hand	0.595	0.405	0.000
S68 Traumatic amputation of wrist and hand	0.595	0.405	0.000
S67 Crushing injury of wrist and hand	0.595	0.405	0.000
S65 Injury of blood vessels at wrist and hand level	0.595	0.405	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.595	0.405	0.000
S60 Superficial injury of wrist and hand	0.595	0.405	0.000
K35-K38 Diseases of appendix	0.594	0.406	0.000
D06 Carcinoma in situ of cervix uteri	0.593	0.407	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.593	0.407	0.000
H02.9 Disorder of eyelid, unspecified	0.593	0.407	0.000
N18.3 Chronic kidney disease, stage 3	0.592	0.408	0.000
C15-C26 Malignant neoplasms of digestive organs	0.591	0.409	0.000
S80 Superficial injury of lower leg	0.589	0.411	0.000
H80-H83 Diseases of inner ear	0.589	0.411	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.589	0.411	0.000
K81 Cholecystitis	0.588	0.411	0.000
E10.9 Without complications	0.587	0.413	0.000
N03 Chronic nephritic syndrome	0.586	0.414	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.585	0.415	0.000
N60.1 Diffuse cystic mastopathy	0.585	0.415	0.000
O32.1 Maternal care for breech presentation	0.585	0.415	0.000
E05.9 Thyrotoxicosis, unspecified	0.584	0.416	0.000
F32.1 Moderate depressive episode	0.583	0.416	0.000
O63.9 Long labour, unspecified	0.583	0.417	0.000
K50-K52 Noninfective enteritis and colitis	0.583	0.417	0.000
H51 Other disorders of binocular movement	0.582	0.417	0.000
H49 Paralytic strabismus	0.582	0.417	0.000
E04.8 Other specified non-toxic goitre	0.582	0.418	0.000
E04.0 Non-toxic diffuse goitre	0.582	0.418	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.582	0.418	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.582	0.418	0.000
Y35-Y36 Legal intervention and operations of war	0.582	0.418	0.000
Y10-Y34 Event of undetermined intent	0.582	0.418	0.000
Y00-Y09 Assault	0.582	0.418	0.000
X85-X99 Assault	0.582	0.418	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.582	0.418	0.000
X50-X57 Overexertion, travel and privation	0.582	0.418	0.000
X30-X39 Exposure to forces of nature	0.582	0.418	0.000
X20-X29 Contact with venomous animals and plants	0.582	0.418	0.000
X10-X19 Contact with heat and hot substances	0.582	0.418	0.000
X00-X09 Exposure to smoke, fire and flames	0.582	0.418	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.582	0.418	0.000
W75-W84 Other accidental threats to breathing	0.582	0.418	0.000
W65-W74 Accidental drowning and submersion	0.582	0.418	0.000
W50-W64 Exposure to animate mechanical forces	0.582	0.418	0.000
W20-W49 Exposure to inanimate mechanical forces	0.582	0.418	0.000
V98-V99 Other and unspecified transport accidents	0.582	0.418	0.000
V95-V97 Air and space transport accidents	0.582	0.418	0.000
V90-V94 Water transport accidents	0.582	0.418	0.000
V80-V89 Other land transport accidents	0.582	0.418	0.000
V70-V79 Bus occupant injured in transport accident	0.582	0.418	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.582	0.418	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.582	0.418	0.000
V40-V49 Car occupant injured in transport accident	0.582	0.418	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.582	0.418	0.000
V20-V29 Motorcycle rider injured in transport accident	0.582	0.418	0.000
V10-V19 Pedal cyclist injured in transport accident	0.582	0.418	0.000
V01-V09 Pedestrian injured in transport accident	0.582	0.418	0.000
N80.8 Other endometriosis	0.582	0.418	0.000
N80.6 Endometriosis in cutaneous scar	0.582	0.418	0.000
N80.5 Endometriosis of intestine	0.582	0.418	0.000
N80.4 Endometriosis of rectovaginal septum and vagina	0.582	0.418	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.581	0.419	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.581	0.419	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.581	0.419	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.581	0.419	0.000
N80.1 Endometriosis of ovary	0.581	0.419	0.000
D04 Carcinoma in situ of skin	0.580	0.419	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.580	0.419	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.580	0.419	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.580	0.419	0.000
K05 Gingivitis and periodontal diseases	0.579	0.421	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.579	0.421	0.000
K85.9 Acute pancreatitis, unspecified	0.578	0.422	0.000
O36 Maternal care for other known or suspected foetal problems	0.577	0.423	0.000
H57 Other disorders of eye and adnexa	0.577	0.423	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.577	0.423	0.000
K40-K46 Hernia	0.576	0.424	0.000
H02.1 Ectropion of eyelid	0.575	0.425	0.000
D25.9 Leiomyoma of uterus, unspecified	0.574	0.426	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.574	0.426	0.000
T92 Sequelae of injuries of upper limb	0.573	0.427	0.000
N64.1 Fat necrosis of breast	0.573	0.427	0.000
H50 Other strabismus	0.572	0.427	0.000
C50.4 Upper-outer quadrant of breast	0.572	0.428	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.572	0.428	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.572	0.428	0.000
E15 Nondiabetic hypoglycaemic coma	0.570	0.430	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.570	0.430	0.000
H27 Other disorders of lens	0.570	0.430	0.000
O04 Medical abortion	0.570	0.430	0.000
S82 Fracture of lower leg, including ankle	0.569	0.431	0.000
S89 Other and unspecified injuries of lower leg	0.569	0.431	0.000
S88 Traumatic amputation of lower leg	0.569	0.431	0.000
S87 Crushing injury of lower leg	0.569	0.431	0.000
S86 Injury of muscle and tendon at lower leg level	0.569	0.431	0.000
S85 Injury of blood vessels at lower leg level	0.569	0.431	0.000
S84 Injury of nerves at lower leg level	0.569	0.431	0.000
C73 Malignant neoplasm of thyroid gland	0.568	0.432	0.000
N60.4 Mammary duct ectasia	0.568	0.432	0.000
D05 Carcinoma in situ of breast	0.568	0.432	0.000
H61 Other disorders of external ear	0.567	0.433	0.000
O02.9 Abnormal product of conception, unspecified	0.565	0.435	0.000
O02.8 Other specified abnormal products of conception	0.565	0.435	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.565	0.435	0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.564	0.436	0.000
O45 Premature separation of placenta [abruptio placentae]	0.564	0.436	0.000
O44 Placenta praevia	0.564	0.436	0.000
O43 Placental disorders	0.564	0.436	0.000
O41 Other disorders of amniotic fluid and membranes	0.564	0.436	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.564	0.436	0.000
O33 Maternal care for known or suspected disproportion	0.564	0.436	0.000
O31 Complications specific to multiple gestation	0.564	0.436	0.000
O30 Multiple gestation	0.564	0.436	0.000
O40 Polyhydramnios	0.564	0.436	0.000
T51 Toxic effect of alcohol	0.564	0.436	0.000
S56 Injury of muscle and tendon at forearm level	0.563	0.436	0.000
H72 Perforation of tympanic membrane	0.563	0.437	0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle	0.562	0.438	0.000
H54 Blindness and low vision	0.561	0.439	0.000
N97 Female infertility	0.560	0.440	0.000
O47 False labour	0.560	0.440	0.000
E03.9 Hypothyroidism, unspecified	0.560	0.440	0.000
N84.1 Polyp of cervix uteri	0.560	0.440	0.000
K74 Fibrosis and cirrhosis of liver	0.560	0.440	0.000
Q60-Q64 Congenital malformations of the urinary system	0.559	0.441	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.559	0.441	0.000
T93 Sequelae of injuries of lower limb	0.558	0.442	0.000
H52.3 Anisometropia and aniseikonia	0.557	0.443	0.000
H90 Conductive and sensorineural hearing loss	0.557	0.443	0.000
K82 Other diseases of gallbladder	0.556	0.443	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.556	0.444	0.000
O80-O84 Delivery	0.554	0.445	0.001
N89 Other noninflammatory disorders of vagina	0.554	0.445	0.000
D35.1 Parathyroid gland	0.554	0.446	0.000
K01 Embedded and impacted teeth	0.552	0.447	0.000
H73 Other disorders of tympanic membrane	0.552	0.448	0.000
H34 Retinal vascular occlusions	0.551	0.449	0.000
E04.1 Non-toxic single thyroid nodule	0.550	0.450	0.000
T43.9 Psychotropic drug, unspecified	0.550	0.450	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.550	0.450	0.000
T43.6 Psychostimulants with abuse potential	0.550	0.450	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.550	0.450	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.550	0.450	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.550	0.450	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.550	0.450	0.000
D10.3 Other and unspecified parts of mouth	0.550	0.450	0.000
H02.7 Other degenerative disorders of eyelid and periocular area	0.550	0.450	0.000
H02.6 Xanthelasma of eyelid	0.550	0.450	0.000
H02.5 Other disorders affecting eyelid function	0.550	0.450	0.000
H02.2 Lagophthalmos	0.550	0.450	0.000
F38 Other mood [affective] disorders	0.549	0.451	0.000
F34 Persistent mood [affective] disorders	0.549	0.451	0.000
F30 Manic episode	0.549	0.451	0.000
F39 Unspecified mood [affective] disorder	0.549	0.451	0.000
T40.2 Other opioids	0.548	0.452	0.000
W00-W19 Falls	0.547	0.452	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations