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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11108227
log Bayes Factor = 16.4201
Chromosome 12   position 96,134,001  (GRCh37) Explore rs11108227 on Ensembl!
Variant rs11108227 is part of Cluster X0214

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.998 0.002 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.997 0.003 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.996 0.004 0.000
Chapter VII Diseases of the eye and adnexa
0.996 0.004 0.000
Chapter VI Diseases of the nervous system
0.993 0.007 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.987 0.013 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.985 0.015 0.000
O60-O75 Complications of labour and delivery
0.982 0.018 0.000
Z47 Other orthopaedic follow-up care
0.980 0.020 0.000
Chapter V Mental and behavioural disorders
0.979 0.021 0.000
H30-H36 Disorders of choroid and retina
0.976 0.024 0.000
C50-C50 Malignant neoplasm of breast
0.972 0.028 0.000
W00-W19 Falls
0.972 0.028 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.970 0.030 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.968 0.032 0.000
Z85 Personal history of malignant neoplasm
0.968 0.032 0.000
Z42 Follow-up care involving plastic surgery
0.968 0.032 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.967 0.033 0.000
G90-G99 Other disorders of the nervous system
0.966 0.034 0.000
H35 Other retinal disorders
0.962 0.038 0.000
S60-S69 Injuries to the wrist and hand
0.957 0.043 0.000
C50 Malignant neoplasm of breast
0.954 0.046 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.954 0.046 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.951 0.049 0.000
O36 Maternal care for other known or suspected foetal problems
0.943 0.057 0.000
W19 Unspecified fall
0.940 0.060 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.940 0.060 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.932 0.068 0.000
Z98 Other postsurgical states
0.930 0.070 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.928 0.072 0.000
O70 Perineal laceration during delivery
0.923 0.077 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.922 0.078 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.918 0.082 0.000
Z48 Other surgical follow-up care
0.916 0.084 0.000
S00-S09 Injuries to the head
0.915 0.085 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.910 0.090 0.000
O47 False labour
0.909 0.091 0.000
C50.4 Upper-outer quadrant of breast
0.905 0.095 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.903 0.097 0.000
O63 Long labour
0.903 0.097 0.000
Y83.6 Removal of other organ (partial) (total)
0.903 0.097 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.902 0.098 0.000
W19.9 Unspecified place
0.902 0.098 0.000
Z98.1 Arthrodesis status
0.901 0.099 0.000
Z96 Presence of other functional implants
0.901 0.099 0.000
G93 Other disorders of brain
0.897 0.103 0.000
R26 Abnormalities of gait and mobility
0.895 0.105 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.892 0.108 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.891 0.109 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.888 0.112 0.000
H35.3 Degeneration of macula and posterior pole
0.887 0.113 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.879 0.121 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.875 0.125 0.000
S80-S89 Injuries to the knee and lower leg
0.874 0.126 0.000
H36 Retinal disorders in diseases classified elsewhere
0.870 0.130 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.867 0.133 0.000
W20-W49 Exposure to inanimate mechanical forces
0.866 0.134 0.000
Y83.4 Other reconstructive surgery
0.865 0.135 0.000
O42 Premature rupture of membranes
0.864 0.136 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.859 0.141 0.000
C44 Other malignant neoplasms of skin
0.856 0.144 0.000
O70.1 Second degree perineal laceration during delivery
0.856 0.144 0.000
O00-O08 Pregnancy with abortive outcome
0.851 0.149 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.851 0.149 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.849 0.151 0.000
H35.8 Other specified retinal disorders
0.845 0.155 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.844 0.156 0.000
S68 Traumatic amputation of wrist and hand
0.842 0.158 0.000
Z96.1 Presence of intraocular lens
0.839 0.161 0.000
Z48.9 Surgical follow-up care, unspecified
0.838 0.162 0.000
G20-G26 Extrapyramidal and movement disorders
0.836 0.164 0.000
O36.8 Maternal care for other specified foetal problems
0.835 0.165 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.834 0.166 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.833 0.167 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.833 0.167 0.000
O63.1 Prolonged second stage (of labour)
0.833 0.167 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.833 0.167 0.000
H40-H42 Glaucoma
0.832 0.167 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.832 0.168 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.831 0.169 0.000
D00-D09 In situ neoplasms
0.831 0.169 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.831 0.169 0.000
R15 Faecal incontinence
0.830 0.170 0.000
R25 Abnormal involuntary movements
0.828 0.172 0.000
Z45 Adjustment and management of implanted device
0.827 0.173 0.000
O47.9 False labour, unspecified
0.827 0.173 0.000
S70-S79 Injuries to the hip and thigh
0.825 0.175 0.000
G35 Multiple sclerosis
0.825 0.175 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.824 0.176 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.823 0.177 0.000
S61 Open wound of wrist and hand
0.820 0.180 0.000
C51-C58 Malignant neoplasms of female genital organs
0.819 0.181 0.000
F99-F99 Unspecified mental disorder
0.819 0.181 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.819 0.181 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.815 0.185 0.000
D10-D36 Benign neoplasms
0.815 0.185 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.814 0.186 0.000
R13 Dysphagia
0.814 0.186 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.813 0.187 0.000
F10.0 Acute intoxication
0.813 0.187 0.000
Z40 Prophylactic surgery
0.810 0.190 0.000
H25-H28 Disorders of lens
0.806 0.194 0.000
S50-S59 Injuries to the elbow and forearm
0.806 0.194 0.000
S90-S99 Injuries to the ankle and foot
0.805 0.195 0.000
O30 Multiple gestation
0.803 0.197 0.000
Y84.8 Other medical procedures
0.797 0.203 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.796 0.204 0.000
H36.0 Diabetic retinopathy
0.795 0.205 0.000
C44.7 Skin of lower limb, including hip
0.794 0.206 0.000
Z48.0 Attention to surgical dressings and sutures
0.794 0.206 0.000
G93.8 Other specified disorders of brain
0.794 0.206 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.794 0.206 0.000
O48 Prolonged pregnancy
0.794 0.206 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.793 0.207 0.000
O36.6 Maternal care for excessive foetal growth
0.793 0.207 0.000
Z71.8 Other specified counselling
0.793 0.207 0.000
Z93 Artificial opening status
0.792 0.208 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.792 0.208 0.000
H35.4 Peripheral retinal degeneration
0.792 0.208 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.786 0.214 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.785 0.215 0.000
Z89 Acquired absence of limb
0.781 0.219 0.000
C50.0 Nipple and areola
0.781 0.219 0.000
C50.2 Upper-inner quadrant of breast
0.781 0.219 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.780 0.220 0.000
F80-F89 Disorders of psychological development
0.780 0.220 0.000
S09 Other and unspecified injuries of head
0.777 0.223 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.776 0.223 0.000
G95 Other diseases of spinal cord
0.776 0.224 0.000
R12 Heartburn
0.776 0.224 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.775 0.225 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.774 0.226 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.773 0.227 0.000
Z43 Attention to artificial openings
0.770 0.230 0.000
Z97 Presence of other devices
0.770 0.230 0.000
Z50 Care involving use of rehabilitation procedures
0.769 0.231 0.000
H35.9 Retinal disorder, unspecified
0.769 0.231 0.000
F30-F39 Mood [affective] disorders
0.768 0.232 0.000
S01 Open wound of head
0.768 0.232 0.000
H43-H45 Disorders of vitreous body and globe
0.767 0.233 0.000
Y84.0 Cardiac catheterisation
0.766 0.234 0.000
R00 Abnormalities of heart beat
0.766 0.234 0.000
O42.9 Premature rupture of membranes, unspecified
0.764 0.236 0.000
G91 Hydrocephalus
0.764 0.236 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.764 0.236 0.000
H35.7 Separation of retinal layers
0.762 0.238 0.000
C50.8 Overlapping lesion of breast
0.762 0.238 0.000
Z85.6 Personal history of leukaemia
0.762 0.238 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.762 0.238 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.762 0.238 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.760 0.240 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.759 0.241 0.000
Z41 Procedures for purposes other than remedying health state
0.759 0.241 0.000
W19.2 School, other institution and public administrative area
0.759 0.241 0.000
S60 Superficial injury of wrist and hand
0.758 0.241 0.000
O73 Retained placenta and membranes, without haemorrhage
0.758 0.242 0.000
Chapter XXII Codes for special purposes
0.757 0.242 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.757 0.243 0.000
W08 Fall involving other furniture
0.756 0.244 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.755 0.245 0.000
O70.0 First degree perineal laceration during delivery
0.754 0.246 0.000
F10.2 Dependence syndrome
0.753 0.247 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.753 0.247 0.000
R14 Flatulence and related conditions
0.752 0.248 0.000
C50.5 Lower-outer quadrant of breast
0.752 0.248 0.000
Z96.8 Presence of other specified functional implants
0.752 0.248 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.751 0.248 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.751 0.249 0.000
H25 Senile cataract
0.749 0.251 0.000
H10-H13 Disorders of conjunctiva
0.748 0.251 0.000
G93.6 Cerebral oedema
0.748 0.252 0.000
G30-G32 Other degenerative diseases of the nervous system
0.748 0.252 0.000
W22 Striking against or struck by other objects
0.746 0.254 0.000
R00.2 Palpitations
0.745 0.255 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.744 0.256 0.000
D25 Leiomyoma of uterus
0.744 0.256 0.000
O36.9 Maternal care for foetal problem, unspecified
0.743 0.257 0.000
O46.9 Antepartum haemorrhage, unspecified
0.742 0.258 0.000
R29.6 Tendency to fall, not elsewhere classified
0.740 0.260 0.000
Y84.2 Radiological procedure and radiotherapy
0.739 0.261 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.738 0.262 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.737 0.263 0.000
Z45.2 Adjustment and management of vascular access device
0.736 0.264 0.000
W06 Fall involving bed
0.736 0.264 0.000
Y84.6 Urinary catheterisation
0.736 0.264 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.736 0.264 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.735 0.265 0.000
Y88 Sequelae of surgical and medical care as external cause
0.734 0.266 0.000
C44.3 Skin of other and unspecified parts of face
0.734 0.266 0.000
T79-T79 Certain early complications of trauma
0.733 0.267 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.732 0.268 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.731 0.269 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.731 0.269 0.000
F10.1 Harmful use
0.731 0.269 0.000
M50-M54 Other dorsopathies
0.729 0.271 0.000
G37 Other demyelinating diseases of central nervous system
0.729 0.271 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.728 0.272 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.728 0.272 0.000
X60-X84 Intentional self-harm
0.727 0.273 0.000
S20-S29 Injuries to the thorax
0.727 0.273 0.000
C92 Myeloid leukaemia
0.726 0.274 0.000
T66-T78 Other and unspecified effects of external causes
0.725 0.275 0.000
W10 Fall on and from stairs and steps
0.725 0.275 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.724 0.276 0.000
F10.3 Withdrawal state
0.724 0.276 0.000
G93.9 Disorder of brain, unspecified
0.724 0.276 0.000
O80-O84 Delivery
0.723 0.277 0.000
R25.1 Tremor, unspecified
0.720 0.280 0.000
Z96.6 Presence of orthopaedic joint implants
0.719 0.281 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.718 0.281 0.000
Z94 Transplanted organ and tissue status
0.718 0.282 0.000
Z37 Outcome of delivery
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V20-V29 Motorcycle rider injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.716 0.284 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
Z54 Convalescence
0.716 0.284 0.000
Z49 Care involving dialysis
0.716 0.284 0.000
Z44 Fitting and adjustment of external prosthetic device
0.716 0.284 0.000
H52 Disorders of refraction and accommodation
0.716 0.284 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.715 0.284 0.000
H40 Glaucoma
0.715 0.285 0.000
O45 Premature separation of placenta [abruptio placentae]
0.715 0.285 0.000
O44 Placenta praevia
0.715 0.285 0.000
O43 Placental disorders
0.715 0.285 0.000
O41 Other disorders of amniotic fluid and membranes
0.715 0.285 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.715 0.285 0.000
O33 Maternal care for known or suspected disproportion
0.715 0.285 0.000
O31 Complications specific to multiple gestation
0.715 0.285 0.000
O40 Polyhydramnios
0.715 0.285 0.000
H55-H59 Other disorders of eye and adnexa
0.714 0.286 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.714 0.286 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.713 0.287 0.000
G70-G73 Diseases of myoneural junction and muscle
0.712 0.288 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.712 0.288 0.000
C71 Malignant neoplasm of brain
0.712 0.288 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.712 0.288 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.711 0.289 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.708 0.292 0.000
Z52 Donors of organs and tissues
0.707 0.293 0.000
Y83.9 Surgical procedure, unspecified
0.706 0.294 0.000
Y83.5 Amputation of limb(s)
0.706 0.294 0.000
Y83.0 Surgical operation with transplant of whole organ
0.706 0.294 0.000
C50.9 Breast, unspecified
0.706 0.294 0.000
W19.4 Street and highway
0.706 0.294 0.000
O66 Other obstructed labour
0.705 0.295 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.705 0.295 0.000
O74 Complications of anaesthesia during labour and delivery
0.704 0.296 0.000
O71 Other obstetric trauma
0.704 0.296 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.704 0.296 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.704 0.296 0.000
O61 Failed induction of labour
0.704 0.296 0.000
O60 Preterm delivery
0.704 0.296 0.000
F99 Mental disorder, not otherwise specified
0.704 0.296 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.703 0.297 0.000
O63.9 Long labour, unspecified
0.703 0.297 0.000
Z47.9 Orthopaedic follow-up care, unspecified
0.703 0.297 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.702 0.298 0.000
F70-F79 Mental retardation
0.702 0.298 0.000
F60-F69 Disorders of adult personality and behaviour
0.702 0.298 0.000
O02 Other abnormal products of conception
0.702 0.298 0.000
Z47.8 Other specified orthopaedic follow-up care
0.701 0.299 0.000
H35.0 Background retinopathy and retinal vascular changes
0.701 0.299 0.000
S02 Fracture of skull and facial bones
0.701 0.299 0.000
S61.0 Open wound of finger(s) without damage to nail
0.700 0.300 0.000
R47-R49 Symptoms and signs involving speech and voice
0.700 0.300 0.000
M20-M25 Other joint disorders
0.700 0.300 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.700 0.300 0.000
H31 Other disorders of choroid
0.700 0.300 0.000
H30 Chorioretinal inflammation
0.700 0.300 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.699 0.300 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.699 0.301 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.699 0.301 0.000
O62 Abnormalities of forces of labour
0.698 0.302 0.000
W07 Fall involving chair
0.698 0.302 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.698 0.302 0.000
D25.9 Leiomyoma of uterus, unspecified
0.698 0.302 0.000
W18 Other fall on same level
0.697 0.303 0.000
W17 Other fall from one level to another
0.697 0.303 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.697 0.303 0.000
W15 Fall from cliff
0.697 0.303 0.000
W14 Fall from tree
0.697 0.303 0.000
W13 Fall from, out of or through building or structure
0.697 0.303 0.000
W12 Fall on and from scaffolding
0.697 0.303 0.000
W11 Fall on and from ladder
0.697 0.303 0.000
W09 Fall involving playground equipment
0.697 0.303 0.000
W05 Fall involving wheelchair
0.697 0.303 0.000
W04 Fall while being carried or supported by other persons
0.697 0.303 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.697 0.303 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.697 0.303 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.697 0.303 0.000
W00 Fall on same level involving ice and snow
0.697 0.303 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.697 0.303 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.696 0.304 0.000
Z84 Family history of other conditions
0.695 0.305 0.000
Z81 Family history of mental and behavioural disorders
0.695 0.305 0.000
Y86 Sequelae of other accidents
0.694 0.306 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.694 0.306 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.694 0.306 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.694 0.306 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.694 0.306 0.000
Z42.9 Follow-up care involving plastic surgery, unspecified
0.694 0.306 0.000
Z42.8 Follow-up care involving plastic surgery of other body part
0.694 0.306 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.694 0.306 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.694 0.306 0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk
0.694 0.306 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.694 0.306 0.000
O03 Spontaneous abortion
0.693 0.306 0.000
D04 Carcinoma in situ of skin
0.693 0.307 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.692 0.307 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.692 0.307 0.000
G96 Other disorders of central nervous system
0.692 0.307 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.692 0.307 0.000
G90 Disorders of autonomic nervous system
0.692 0.307 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.692 0.307 0.000
G92 Toxic encephalopathy
0.692 0.307 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.692 0.308 0.000
H50 Other strabismus
0.692 0.308 0.000
R27 Other lack of coordination
0.691 0.308 0.000
C83.3 Large cell (diffuse)
0.690 0.310 0.000
V10-V19 Pedal cyclist injured in transport accident
0.690 0.310 0.000
C44.5 Skin of trunk
0.690 0.310 0.000
G20 Parkinson's disease
0.690 0.310 0.000
H35.6 Retinal haemorrhage
0.690 0.310 0.000
H35.5 Hereditary retinal dystrophy
0.690 0.310 0.000
H35.2 Other proliferative retinopathy
0.690 0.310 0.000
H35.1 Retinopathy of prematurity
0.690 0.310 0.000
C44.0 Skin of lip
0.690 0.310 0.000
R00.1 Bradycardia, unspecified
0.689 0.311 0.000
S69 Other and unspecified injuries of wrist and hand
0.686 0.314 0.000
S67 Crushing injury of wrist and hand
0.686 0.314 0.000
S65 Injury of blood vessels at wrist and hand level
0.686 0.314 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.686 0.314 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.686 0.314 0.000
G57 Mononeuropathies of lower limb
0.685 0.315 0.000
C64-C68 Malignant neoplasms of urinary tract
0.684 0.315 0.000
Z33 Pregnant state, incidental
0.684 0.316 0.000
Z50.8 Care involving use of rehabilitation procedures
0.684 0.316 0.000
C50.6 Axillary tail of breast
0.684 0.316 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.684 0.316 0.000
S81 Open wound of lower leg
0.683 0.317 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.681 0.319 0.000
Z50.1 Other physical therapy
0.681 0.319 0.000
R26.3 Immobility
0.681 0.319 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.680 0.320 0.000
S09.9 Unspecified injury of head
0.679 0.321 0.000
Y85 Sequelae of transport accidents
0.679 0.321 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.679 0.321 0.000
Z98.0 Intestinal bypass and anastomosis status
0.677 0.323 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.677 0.323 0.000
Z73 Problems related to life-management difficulty
0.677 0.323 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.677 0.323 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.676 0.323 0.000
O36.4 Maternal care for intra-uterine death
0.676 0.323 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.676 0.323 0.000
O36.2 Maternal care for hydrops foetalis
0.676 0.323 0.000
O36.1 Maternal care for other isoimmunisation
0.676 0.323 0.000
F00 Dementia in Alzheimer's disease
0.676 0.324 0.000
C50.3 Lower-inner quadrant of breast
0.675 0.324 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.675 0.324 0.000
R76 Other abnormal immunological findings in serum
0.675 0.325 0.000
T90 Sequelae of injuries of head
0.675 0.325 0.000
W19.8 Other specified place
0.674 0.326 0.000
W19.5 Trade and service area
0.674 0.326 0.000
W19.0 Home
0.674 0.326 0.000
W19.7 Farm
0.674 0.326 0.000
W19.6 Industrial and construction area
0.674 0.326 0.000
W19.3 Sports and athletics area
0.674 0.326 0.000
W19.1 Residential institution
0.674 0.326 0.000
H16 Keratitis
0.673 0.327 0.000
Z35 Supervision of high-risk pregnancy
0.673 0.327 0.000
M70-M79 Other soft tissue disorders
0.672 0.328 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.672 0.328 0.000
F31 Bipolar affective disorder
0.672 0.328 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.671 0.329 0.000
C83.0 Small cell (diffuse)
0.670 0.330 0.000
S00 Superficial injury of head
0.670 0.330 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.668 0.332 0.000
Y84.9 Medical procedure, unspecified
0.668 0.332 0.000
Y84.7 Blood-sampling
0.668 0.332 0.000
Y84.5 Insertion of gastric or duodenal sound
0.668 0.332 0.000
Y84.4 Aspiration of fluid
0.668 0.332 0.000
Y84.3 Shock therapy
0.668 0.332 0.000
Y84.1 Kidney dialysis
0.668 0.332 0.000
S01.3 Open wound of ear
0.668 0.332 0.000
S62 Fracture at wrist and hand level
0.667 0.333 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.667 0.333 0.000
S82 Fracture of lower leg, including ankle
0.667 0.333 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.665 0.334 0.000
H25.1 Senile nuclear cataract
0.664 0.336 0.000
O30.0 Twin pregnancy
0.664 0.336 0.000
S70 Superficial injury of hip and thigh
0.664 0.336 0.000
D03 Melanoma in situ
0.663 0.337 0.000
H25.0 Senile incipient cataract
0.663 0.337 0.000
R50-R69 General symptoms and signs
0.662 0.338 0.000
O70.9 Perineal laceration during delivery, unspecified
0.661 0.338 0.000
O70.3 Fourth degree perineal laceration during delivery
0.661 0.338 0.000
O70.2 Third degree perineal laceration during delivery
0.661 0.338 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.661 0.339 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.661 0.339 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.661 0.339 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.661 0.339 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.661 0.339 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.661 0.339 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.661 0.339 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.661 0.339 0.000
T36 Poisoning by systemic antibiotics
0.661 0.339 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.661 0.339 0.000
W22.9 Unspecified place
0.660 0.340 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.660 0.340 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.659 0.341 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.659 0.341 0.000
Z93.1 Gastrostomy status
0.659 0.341 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.658 0.342 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.658 0.342 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.658 0.342 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.658 0.342 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.658 0.342 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.658 0.342 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.658 0.342 0.000
F11 Mental and behavioural disorders due to use of opioids
0.658 0.342 0.000
Z71.3 Dietary counselling and surveillance
0.658 0.342 0.000
S06 Intracranial injury
0.658 0.342 0.000
S64 Injury of nerves at wrist and hand level
0.657 0.343 0.000
C15-C26 Malignant neoplasms of digestive organs
0.657 0.343 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.657 0.343 0.000
S51 Open wound of forearm
0.656 0.343 0.000
S08 Traumatic amputation of part of head
0.656 0.344 0.000
S07 Crushing injury of head
0.656 0.344 0.000
S05 Injury of eye and orbit
0.656 0.344 0.000
S04 Injury of cranial nerves
0.656 0.344 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.656 0.344 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.656 0.344 0.000
G25 Other extrapyramidal and movement disorders
0.655 0.345 0.000
C56 Malignant neoplasm of ovary
0.655 0.345 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.654 0.346 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.653 0.347 0.000
G36 Other acute disseminated demyelination
0.652 0.348 0.000
O47.0 False labour before 37 completed weeks of gestation
0.652 0.348 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.651 0.349 0.000
S90 Superficial injury of ankle and foot
0.649 0.351 0.000
O72 Postpartum haemorrhage
0.649 0.351 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.648 0.352 0.000
C95 Leukaemia of unspecified cell type
0.648 0.352 0.000
C94 Other leukaemias of specified cell type
0.648 0.352 0.000
C93 Monocytic leukaemia
0.648 0.352 0.000
C88 Malignant immunoproliferative diseases
0.648 0.352 0.000
C86 Other specified types of T/NK-cell lymphoma
0.648 0.352 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.648 0.352 0.000
C81 Hodgkin's disease
0.648 0.352 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.648 0.352 0.000
R02 Gangrene, not elsewhere classified
0.647 0.353 0.000
E10-E14 Diabetes mellitus
0.646 0.354 0.000
Y83.3 Surgical operation with formation of external stoma
0.646 0.354 0.000
Z96.9 Presence of functional implant, unspecified
0.646 0.354 0.000
Z96.7 Presence of other bone and tendon implants
0.646 0.354 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.646 0.354 0.000
Z96.4 Presence of endocrine implants
0.646 0.354 0.000
Z96.3 Presence of artificial larynx
0.646 0.354 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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